Steve Horvath

Title(s)Adjunct Instructor, Medicine
SchoolMedicine
vCardDownload vCard

    Collapse Bibliographic 
    Collapse publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
    Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Blood DNA Methylation Predicts Long-Term Risk of Dementia in Prospective Cohorts. medRxiv. 2026 Jul 13. Maihofer AX, Mackey CE, Robertson JA, Marioni RE, Nguyen S, McEvoy LK, LaCroix AZ, Espeland MA, Rapp SR, Resnick SM, Zhang B, Horvath S, Beckman K, Libermann TA, Russ TC, Cox SR, Harris SE, Pyrgioti M, Shadyab AH. PMID: 42523536; PMCID: PMC13405541.
      View in: PubMed   Mentions:
    2. Meta-analysis of DNA methylation aging signatures in 17 human tissues. Nat Aging. 2026 Jul; 6(7):1501-1515. Jacques M, Seale K, Voisin S, Lysenko A, Grolaux R, Jones-Freeman B, Lamon S, Abeysooriya M, Levinger I, Bauer C, Sharples AP, Heikkinen A, Sillanpaa E, Ollikainen M, Smith C, Broatch JR, Zarekookandeh N, Gillberg L, Blom I, Poganik JR, Moqri M, Gladyshev VN, Taper M, Malecki C, Lal S, Saurat N, Horvath S, Teschendorff A, Eynon N. PMID: 42362890; PMCID: PMC13375584.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    3. Global and regional DNA methylation patterns in heart failure: a case-control analysis. EBioMedicine. 2026 Jul; 129:106340. Krolevets M, Cate VT, Prochaska JH, Schulz A, Rapp S, Zeid S, Tenzer S, Andrade-Navarro MA, Lu A, Strauch K, Schuster AK, Beutel ME, Heinrich I, Weinmann-Menke J, Lackner KJ, Lurz P, Horvath S, Niehrs C, Wild PS. PMID: 42335675; PMCID: PMC13316289.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    4. Intermittent hypoxia induces reversible epigenetic age acceleration in old mice. NPJ Aging. 2026 Jun 23. Donega S, Lu AT, Haghani A, Horvath M, Yan Q, Baranzini M, Escote MT, Rossi M, Hernandez RJ, McDevitt RA, Fishbein KW, Horvath S, Ferrucci L. PMID: 42337297.
      View in: PubMed   Mentions:
    5. Delphi-derived Framework for Healthspan-Oriented Care: The Cardiometabolic Health Perspective. Aging Dis. 2026 Jun 04. Postula M, Kistkins S, Nowak-Szwed A, DeRosa S, Kaminski K, Erat A, Kletnieks U, Moser O, Bliznuks D, Stambler I, Sjundjukovs E, Rabinovici J, Scheibye-Knudsen M, Zhavoronkov A, Gladyshev VN, Horvath S, Vellas B, Kuchel GA, Sourij H, Bischof E, Pfeiffer AFH. PMID: 42295087.
      View in: PubMed   Mentions:    Fields:    
    6. Correction to: Searching for shared epigenetic clocks: evaluating ultra‑conserved markers in a de novo genome assembly of the albacore tuna. Geroscience. 2026 Jun; 48(3):5103-5104. Chevrier T, Bonhommeau S, Thompson M, Farley J, Del Vecchio G, Nieblas AE, Cowart DA, Chanut J, Nguy?n JI, Bernard S, Guiguen Y, Cabau C, Klopp C, Zoller JA, Horvath S, Brooke R, Lu AT, Pellegrini M. PMID: 42053912.
      View in: PubMed   Mentions:    Fields:    
    7. Association of epigenetic age acceleration with MRI biomarkers of aging and Alzheimer's disease neurodegeneration. Aging (Albany NY). 2026 Apr 07; 18(1):303-326. McEvoy LK, Zhang B, Nguyen S, Maihofer AX, Nievergelt CM, Casanova R, Horvath S, Lu AT, Davatzikos C, Erus G, Resnick SM, Espeland MA, Rapp S, Beckman K, Ferrucci L, LaCroix AZ, Shadyab AH. PMID: 41949889; PMCID: PMC13285947.
      View in: PubMed   Mentions:    Fields:    
    8. Toward actionable interventions in human aging (12th ARDD meeting, 2025). Aging (Albany NY). 2026 Apr 06; 18(1):282-302. Dekan A, Lore S, Yoon YE, Sjöholm A, Tyshkovskiy A, Terskikh A, Cuervo AM, Georgievskaya A, Heinz A, Seluanov A, Adams A, Tsai AP, Murray A, Brunet A, Harten AMV, Spier A, Shenhar B, Pedersen BK, Clasen B, Schumacher B, Kennedy BK, Suetta C, Volbracht C, Kuppe C, Cookson C, Ewald CY, Banila C, Cai D, Valenzano DR, Lamming DW, Rudnic E, Samra EB, Teeling E, Verdin E, Fang EF, Fagagna FDD, Galkin F, Zmudze G, Jasper H, Jang IH, Han JJ, Justice J, Hoeijmakers JHJ, Ramos JMP, Lemaitre JM, Aerssens J, Betts-LaCroix J, Newman JC, Belmonte JCI, Kawamura K, Schaal KM, Egerton K, Abdelmohsen K, Fortney K, Hartenstein L, Niedernhofer L, Katsimpardi L, Melton L, Knudsen LB, Ferrucci L, Sylow L, Demaria M, Schafer MJ, Guasch-Ferré M, Borch-Jensen M, Kholin M, Antonov M, Levitt M, Deleidi M, Merad M, Meldal M, Topors M, Venkatesan M, LeBrasseur NK, Anzinger N, Fedichev P, Kohlhaas P, Mullen PJ, Singhal P, Cabo R, Houtkooper RH, Montgomery R, Smith R, Rosenzweig-Lipson S, Jakimov S, Horvath S, Austad S, Rando TA, White T, Zuber T, Rozmaric T, Wyss-Coray T, Tammela T, Gladyshev VN, Sinatti VVC, Wang W, Harborne W, Liu X, Wang XL, Suh Y, Lee Y, Koch Z, Zhavoronkov A, Scheibye-Knudsen M, Bakula D. PMID: 41944812; PMCID: PMC13285953.
      View in: PubMed   Mentions:    Fields:    
    9. Quadriceps mitochondrial DNA quantity, quality, and gene expression after 2 years of calorie restriction: exploratory results from the CALERIE trial. Geroscience. 2026 Mar 26. Das JK, Zhang Y, Redman LM, Martin CK, Das SK, Racette SB, Herbst A, Liu N, Allison DB, McKenzie D, Aiken JM, Horvath S, Candia J, Banskota N, Ferrucci L, Kraus WE, Huffman KM, Wanagat J. PMID: 41886216.
      View in: PubMed   Mentions:    Fields:    
    10. Searching for shared epigenetic clocks: evaluating ultra-conserved markers in a de novo genome assembly of the albacore tuna. Geroscience. 2026 Jun; 48(3):3831-3845. Chevrier T, Bonhommeau S, Thompson M, Farley J, Del Vecchio G, Nieblas AE, Cowart DA, Nguy?n JI, Bernard S, Guiguen Y, Cabau C, Klopp C, Zoller JA, Horvath S, Brooke R, Lu AT, Pellegrini M, Chanut J. PMID: 41874768.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    11. Trajectories of physical function and biological aging in generally healthy older adults with and without incident invasive cancer over a three-year follow-up: findings from the DO-HEALTH study. NPJ Aging. 2026 Mar 23; 12(1). Rösler W, Kistler-Fischbacher M, Gängler S, Manz MG, Reto KW, Orav JE, Dawson-Hughes B, Ryan J, Belsky DW, Horvath S, Willett WC, Wieczorek M, Bischoff-Ferrari HA. PMID: 41872206; PMCID: PMC13396198.
      View in: PubMed   Mentions:
    12. Longitudinal changes in epigenetic clocks predict survival in the InCHIANTI cohort. Nat Aging. 2026 Mar; 6(3):534-540. Kuo PL, Moore AZ, Tanaka T, Belsky DW, Lu AT, Horvath S, Bandinelli S, Ferrucci L. PMID: 41826710; PMCID: PMC13004684.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    13. Vitamin C inhibits ACSL4 to alleviate ferro-aging in primates. Cell Metab. 2026 Apr 07; 38(4):673-693.e17. Liu L, Zheng Z, You W, Yang P, Wen Y, Qiao Y, Ma S, Zhang H, Zhang S, Xu G, Ma C, Tian A, Jiang M, Zhang T, Geng L, Li J, Sun X, Wang F, Xiong M, Yang Y, Lu X, Jiang X, Dong X, Zhang Z, Huang Y, Zhang B, Qiao Q, Sun S, Fan Y, Cai Y, Yan K, Zhang Y, Jing Y, Jing Y, Wang Q, Lei J, Tan A, Han Z, Reddy P, Haghani A, Rodriguez Esteban C, Zhang F, Liu Z, Liu N, Wang S, Horvath S, Yang J, Izpisua Belmonte JC, Zhang W, Qu J, Liu GH. PMID: 41819088.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimals
    14. Parental kinship influences global methylation and epigenetic age estimation in Peromyscus. Genetics. 2026 03 04; 232(3). Huynh-Dam KT, Jaeger C, Chatzistamou I, Horvath S, Kiaris H. PMID: 41466352; PMCID: PMC13017600.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    15. Epigenetic Clocks of Biological Aging and Risk of Incident Mild Cognitive Impairment and Dementia: The Women's Health Initiative Memory Study. Aging Cell. 2026 Mar; 25(3):e70424. Nguyen S, Lu AT, Horvath S, Espeland MA, Rapp SR, Maihofer AX, Nievergelt CM, LaCroix AZ, McEvoy LK, Resnick SM, Beckman K, Shadyab AH. PMID: 41721741; PMCID: PMC12928021.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    16. Sex-specific nonlinear DNA methylation aging trajectories reveal biomarkers of cancer risk and inflammation. Genome Biol. 2026 Feb 04; 27(1):2. Grolaux R, Jacques M, Jones-Freeman B, Horvath S, Teschendorff A, Eynon N. PMID: 41634811; PMCID: PMC12870970.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    17. Association of epigenetic age acceleration with MRI biomarkers of aging and Alzheimer's disease neurodegeneration. medRxiv. 2026 Jan 26. McEvoy LK, Zhang B, Nguyen S, Maihofer AX, Nievergelt CM, Casanova R, Horvath S, Lu AT, Davatzikos C, Erus G, Resnick SM, Espeland MA, Rapp SR, Beckman K, Ferrucci L, Lacroix AZ, Shadyab AH. PMID: 41646682; PMCID: PMC12870710.
      View in: PubMed   Mentions:
    18. Epigenetic insights of Olympic champions: nuclear and mitochondrial DNA methylation and regulators of aging. Geroscience. 2026 Jan 17. Teglas T, Torma F, Bori Z, Aczel D, Babszky G, Kawamura T, Higuchi M, Yaodong G, Lee M, Horvath S, Radak Z. PMID: 41547678.
      View in: PubMed   Mentions:    Fields:    
    19. Past, present and future perspectives on the science of aging. Nat Aging. 2026 Jan; 6(1):6-22. Ambrosio F, Artyomov MN, Austad SN, Barzilai N, Belmonte JCI, Belsky DW, Benayoun BA, Brunet A, Dönertas HM, Dubal DB, Fang EF, Feige JN, Fried LP, Furman D, Gao X, Gladyshev VN, Gorbunova V, Gorospe M, Han JJ, Hansson O, Hara E, Horvath S, Ip NY, Kuchel GA, Kaeberlein M, Lamming DW, Levy BR, Liu GH, Lee J, Moffitt TE, Minamino T, Partridge L, Raina P, Rando TA, Rowe JW, Schwartz M, Scott AJ, Sierra F, Sinclair DA, Teunissen CE, Vellas B, Verdin E, Walker KA, Webb AE, Wyss-Coray T, Xu M, Yu JT, Zhavoronkov A, Aman Y, Kriebs A, Ren Q, Walters H, Thuault S. PMID: 41566049.
      View in: PubMed   Mentions: 2     Fields:    
    20. Compatibility and comparative analysis of chronological and biological aging between the legacy 450K and the EPIC v2.0 arrays. Mech Ageing Dev. 2026 02; 229:112142. De Pourcq S, Kuo PL, Moore AZ, Bandinelli S, Horvath S, Ferrucci L, Santini V. PMID: 41354360.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    21. Epigenetic clocks and longitudinal plasma biomarkers of Alzheimer's disease. Alzheimers Dement. 2025 12; 21(12):e70983. Zhang B, McEvoy LK, Nguyen S, Espeland MA, Rapp SR, Horvath S, Lu AT, LaCroix AZ, Nievergelt CM, Maihofer AX, Resnick SM, Mielke MM, Beckman K, Li D, Silver B, Manson JE, Ferrucci L, Shadyab AH. PMID: 41399190; PMCID: PMC12706121.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    22. Towards global healthy longevity: report from the 1st World Longevity Summit in Kyotango, Japan. NPJ Aging. 2025 Nov 18; 11(1):89. Kitani T, Matoba S, Naito Y, Horvath S, Yoshimori T, Chan FKL, Matsuda T, Bandini S, Nakagami H, Morishita R, Nakayama Y, Yaku H. PMID: 41253835; PMCID: PMC12627732.
      View in: PubMed   Mentions:
    23. Dental Ageing Offers New Insights Into the First Epigenetic Clock for Common Dolphins (Delphinus delphis). Ecol Evol. 2025 Nov; 15(11):e72424. Hanninger EF, Peters KJ, Gerber L, Barratclough A, Betty EL, Palmer EI, Horvath S, Stockin KA. PMID: 41234816; PMCID: PMC12611323.
      View in: PubMed   Mentions:
    24. Open problems in ageing science: a roadmap for biogerontology. Geroscience. 2026 Jun; 48(3):3351-3360. Talay A, Belikov AV, To PKP, Alfatemi HH, Alon U, Deelen J, Ewald CY, Gems D, Gorbunova V, Gruber J, Hägg S, Hemming J, Horvath S, Kaya A, Lewis CJ, Maier AB, Marinova MB, Pawelec G, Peleg S, Rattan S, Scheibye-Knudsen M, Schmauck-Medina T, Saroyan V, Seluanov A, Stolzing A, Teeling E, Williams RW, White T, Unfried M, de Magalhães JP. PMID: 41205028; PMCID: PMC13356218.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimals
    25. Beyond the Genotype: A Multi-Omic Analysis of APOEe4's Role in Alzheimer's Disease. bioRxiv. 2025 Oct 16. Markov Y, Priyanka A, Xu L, Wang W, Thrush-Evensen K, Gonzalez J, Borrus D, Kasamoto J, Sehgal R, Zou G, Fraij J, Carlyle BC, Horvath S, Bennett DA, Zhao H, van Dyck CH, Lam TT, Levine ME, Higgins-Chen AT. PMID: 41279801; PMCID: PMC12632733.
      View in: PubMed   Mentions:
    26. Dental aging offers new insights to the first epigenetic clock for common dolphins (Delphinus delphis). bioRxiv. 2025 Oct 13. Hanninger EF, Peters KJ, Gerber L, Barratclough A, Betty EL, Palmer EI, Horvath S, Stockin KA. PMID: 40777509; PMCID: PMC12330489.
      View in: PubMed   Mentions:
    27. Epigenetic clocks of biological aging and risk of incident mild cognitive impairment and dementia: the Women's Health Initiative Memory Study. medRxiv. 2025 Oct 01. Nguyen S, Lu A, Horvath S, Espeland MA, Rapp SR, Maihofer AX, Nievergelt CM, LaCroix AZ, McEvoy LK, Resnick SM, Beckman K, Shadyab AH. PMID: 41256164; PMCID: PMC12622145.
      View in: PubMed   Mentions:
    28. Epigenetic Clock Analysis of Sex Chromosome Aneuploidies. Aging Cell. 2025 11; 24(11):e70243. Zhang J, Teoli J, Rey B, Vieira C, Lemaitre JF, Plotton I, Marais GAB, Horvath S. PMID: 41025454; PMCID: PMC12610412.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    29. Herbal terpenoids activate autophagy and mitophagy through modulation of bioenergetics and protect from metabolic stress, sarcopenia and epigenetic aging. Nat Aging. 2025 Oct; 5(10):2003-2021. Civiletto G, Brunetti D, Lizzo G, Muller K, Jacot GE, Daskalaki I, Sizzano F, Huh M, Di Meo I, Colombo MN, Sanchez-Garcia JL, Bétrisey BJ, Zollinger A, Lino P, Neal C, Egesipe AL, Richard J, Chimen M, Hermant A, Brinon B, Texari L, Metairon S, Qureshi MA, Patel DS, Vanapalli SA, Malavolta M, Gao AW, Lalou A, Provinciali M, Orlando F, Tiranti V, Brooke RT, Horvath S, Auwerx J, Feige JN, Gut P. PMID: 40993327; PMCID: PMC12532568.
      View in: PubMed   Mentions: 2     Fields:    Translation:Animals
    30. Extension of lifespan by epicatechin, halofuginone and mitoglitazone in male but not female genetically heterogeneous mice. Geroscience. 2026 Jun; 48(3):4139-4156. Strong R, Nelson JF, Bogue MA, Colca JR, Denzel M, Diaz V, Finck BN, Gladyshev VN, Horvath S, Jiang N, Keller T, Kletzien RF, Korstanje R, Kumar N, Leeuwenburgh C, Fernandez E, Galecki A, Ginsburg B, Han M, Kaczorowski C, Leiser S, Lopez-Cruzan M, Raj K, Reifsnyder PC, Rosenthal NA, Rosi S, Shindyapina A, Stacpoole P, Salmon AB, Tyshkovskiy A, Walter P, Whitman M, Miller RA, Harrison DE. PMID: 40973907; PMCID: PMC13355999.
      View in: PubMed   Mentions:    Fields:    Translation:Animals
    31. Regenerate to "Rejuvenate": Insights From Adult Resident Stem Cells of Aged Flatworms and Mice. Aging Cell. 2025 11; 24(11):e70236. Murach KA, Dungan CM, Chambers TL, Horvath S, Nandakumar J, Gladyshev VN, Pletcher SD, Dai X, Guo L. PMID: 40947308; PMCID: PMC12611277.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    32. Variations in Innate Immune Cell Subtypes Correlate with Epigenetic Clocks, Inflammaging and Health Outcomes. Adv Sci (Weinh). 2025 Nov; 12(43):e05922. Guo X, Robertson JA, Aparicio A, Seale K, Chen Q, Richmond A, Du Z, Sulaiman M, Zheng SC, Ballestar E, Cecil CA, Heijmans BT, Horvath S, Dwaraka VB, Lasky-Su J, Smith R, Marioni RE, Teschendorff AE. PMID: 40862296; PMCID: PMC12631840.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    33. Epigenetic clocks and longitudinal plasma biomarkers of Alzheimer's disease. medRxiv. 2025 Aug 14. Zhang B, McEvoy LK, Nguyen S, Espeland MA, Rapp SR, Horvath S, Lu A, LaCroix AZ, Nievergelt CM, Maihofer AX, Resnick SM, Mielke MM, Beckman K, Li D, Silver B, Manson JE, Ferrucci L, Shadyab AH. PMID: 40832399; PMCID: PMC12363716.
      View in: PubMed   Mentions:
    34. EnsembleAge: enhancing epigenetic age assessment with a multi-clock framework. Geroscience. 2026 04; 48(2):2873-2886. Haghani A, Lu AT, Yan Q, Belmonte JCI, Reddy P, Cheng V, Yang XW, Wang N, Mozhui K, Murach K, Ocampo A, Williams RW, Jucker M, Bergmann C, Poganik JR, Zhang B, Gladyshev VN, Horvath S. PMID: 40768061; PMCID: PMC12972178.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimals
    35. Epigenetic Age Monitoring in Professional Soccer Players for Tracking Recovery and the Effects of Strenuous Exercise. Aging Cell. 2025 10; 24(10):e70182. Brooke RT, Kocher T, Zauner R, Gordevicius J, Milciute M, Nowakowski M, Haser C, Blobel T, Sieland J, Langhoff D, Banzer W, Horvath S, Pfab F. PMID: 40726009; PMCID: PMC12507406.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCells
    36. Human clinical trial of plasmapheresis effects on biomarkers of aging (efficacy and safety trial). Sci Rep. 2025 Jul 01; 15(1):21059. Borsky P, Holmannova D, Parova H, Horvath S, Sramek P, Brooke RT, Milciute M, Gordevicius J, Fiala Z, Andrys C, Kremlacek J, Rehacek V, Baranova I, Matyasovska N, Borska L. PMID: 40592961; PMCID: PMC12218284.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    37. Biomarkers of Aging-NIA Joint Symposium 2024: New Insights Into Aging Biomarkers. Aging Cell. 2025 07; 24(7):e70124. Herzog C, Poganik JR, Barzilai N, Basisty N, Beerman I, Belsky DW, de Cabo R, Candia J, Faghri F, Horvath S, Maier AB, Perez V, Sen P, Moqri M, Gladyshev VN, Ferrucci L. PMID: 40525821; PMCID: PMC12266742.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    38. Senescence-resistant human mesenchymal progenitor cells counter aging in primates. Cell. 2025 Sep 04; 188(18):5039-5061.e35. Lei J, Xin Z, Liu N, Ning T, Jing Y, Qiao Y, He Z, Jiang M, Yang Y, Zhang Z, Zhao L, Li J, Lv D, Yan Y, Zhang H, Xiao L, Zhang B, Huang H, Sun S, Zheng F, Jiang X, Lu H, Dong X, Yue S, Ma C, Shuai J, Ji Z, Liu F, Ye Y, Yan K, Hu Q, Xu G, Zhao Q, Wu R, Cai Y, Fan Y, Jing Y, Wang Q, Reddy P, Lu X, Zheng Z, Liu B, Haghani A, Ma S, Suzuki K, Rodriguez Esteban C, Yang J, Song M, Horvath S, Zhang W, Li W, Xiang AP, Zhu L, Fu X, Zhao G, Belmonte JCI, Qu J, Wang S, Liu GH. PMID: 40516525.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansAnimalsCells
    39. Circannual breeding and methylation are impacted by the equinox in Peromyscus. BMC Biol. 2025 Jun 02; 23(1):149. Huynh-Dam KT, Jaeger C, Naderi A, Bayram MF, Crossland JP, Kaza V, Barlow S, Chatzistamou I, Long A, Horvath S, Kiaris H. PMID: 40457395; PMCID: PMC12131350.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    40. CMImpute: cross-species and tissue imputation of species-level DNA methylation samples across mammalian species. Genome Biol. 2025 May 20; 26(1):133. Maciejewski E, Horvath S, Ernst J. PMID: 40394556; PMCID: PMC12090574.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimalsCells
    41. DNAm age differences between infinium methylationEPICv1 vs EPICv2 in buffy coat, PBMC, and saliva samples. Commun Biol. 2025 Apr 23; 8(1):654. Tay JH, Chew YE, Wang W, Lim ZM, Guan L, Dorajoo R, Kennedy BK, Brooke R, Gordevicius J, Horvath S, Sandalova E, Maier AB. PMID: 40269264; PMCID: PMC12019316.
      View in: PubMed   Mentions: 10  Translation:HumansCells
    42. At the Nexus Between Epigenetics and Senescence: The Effects of Senolytic (BI01) Administration on DNA Methylation Clock Age and the Methylome in Aged and Regenerated Skeletal Muscle. Aging Cell. 2025 07; 24(7):e70068. Chambers TL, Wells J, Koopmans PJ, Morena F, Malik ZB, Greene NP, Filareto A, Franti M, Sini P, Weinstabl H, Brooke RT, Milciute M, Gordevicius J, Horvath S, Wen Y, Dungan CM, Murach KA. PMID: 40259517; PMCID: PMC12266783.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    43. Invigorating discovery and clinical translation of aging biomarkers. Nat Aging. 2025 Apr; 5(4):539-543. Jacques E, Herzog C, Ying K, Tomusiak A, Kasamoto J, Sehgal R, Paulson S, Reinhard J, Träuble J, Hastings WJ, Tyshkovskiy A, Hägg S, Earls JC, Behrens CE, Lasky-Su J, Zhou G, Morgen E, Tsang JS, Marioni RE, Ma XJ, Stolzing A, Glorioso C, Gootenberg JS, Abudayyeh OO, Argentieri MA, Mak RH, Cox LS, Brack AS, Lauc G, Furman D, Buenrostro JD, Schumacher B, Justice JN, Woods T, Gobel D, Perez VI, Sinclair DA, Maier AB, Barzilai N, Snyder MP, Wyss-Coray T, Horvath S, Ferrucci L, Poganik JR, Moqri M, Gladyshev VN. PMID: 40164770; PMCID: PMC12991831.
      View in: PubMed   Mentions: 1     Fields:    
    44. A torpor-like state in mice slows blood epigenetic aging and prolongs healthspan. Nat Aging. 2025 Mar; 5(3):437-449. Jayne L, Lavin-Peter A, Roessler J, Tyshkovskiy A, Antoszewski M, Ren E, Markovski A, Sun S, Yao H, Sankaran VG, Gladyshev VN, Brooke RT, Horvath S, Griffith EC, Hrvatin S. PMID: 40055478; PMCID: PMC11922754.
      View in: PubMed   Mentions: 8     Fields:    Translation:AnimalsCells
    45. What makes biological age epigenetic clocks tick. Nat Aging. 2025 Mar; 5(3):335-336. Moqri M, Poganik JR, Horvath S, Gladyshev VN. PMID: 39994479; PMCID: PMC12867034.
      View in: PubMed   Mentions: 7     Fields:    
    46. Perspectives on the essence and drivers of aging. Life Med. 2025 Apr; 4(2):lnaf006. Cohen HY, Gorbunova V, Horvath S, Kennedy BK, Li W, de Magalhães JP, Seluanov A, Song M, Suzuki K. PMID: 40567576; PMCID: PMC12187507.
      View in: PubMed   Mentions:
    47. Distinct mismatch-repair complex genes set neuronal CAG-repeat expansion rate to drive selective pathogenesis in HD mice. Cell. 2025 Mar 20; 188(6):1524-1544.e22. Wang N, Zhang S, Langfelder P, Ramanathan L, Gao F, Plascencia M, Vaca R, Gu X, Deng L, Dionisio LE, Vu H, Maciejewski E, Ernst J, Prasad BC, Vogt TF, Horvath S, Aaronson JS, Rosinski J, Yang XW. PMID: 39938516; PMCID: PMC11972609.
      View in: PubMed   Mentions: 21     Fields:    Translation:HumansAnimalsCells
    48. The role of protective genetic variants in modulating epigenetic aging. Geroscience. 2025 08; 47(4):5995-6004. Bejaoui Y, Srour L, Qannan A, Oshima J, Saad C, Horvath S, Mbarek H, El Hajj N. PMID: 39928272; PMCID: PMC12397041.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    49. Individual and additive effects of vitamin D, omega-3 and exercise on DNA methylation clocks of biological aging in older adults from the DO-HEALTH trial. Nat Aging. 2025 Mar; 5(3):376-385. Bischoff-Ferrari HA, Gängler S, Wieczorek M, Belsky DW, Ryan J, Kressig RW, Stähelin HB, Theiler R, Dawson-Hughes B, Rizzoli R, Vellas B, Rouch L, Guyonnet S, Egli A, Orav EJ, Willett W, Horvath S. PMID: 39900648; PMCID: PMC11922767.
      View in: PubMed   Mentions: 46     Fields:    Translation:HumansCells
    50. Enhancing epigenetic aging clocks in cetaceans: accurate age estimations in small endangered delphinids, killer whales, pilot whales, belugas, humpbacks, and bowhead whales. Sci Rep. 2025 02 03; 15(1):4048. Zoller JA, Lu AT, Haghani A, Horvath S, Robeck T. PMID: 39900928; PMCID: PMC11791194.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    51. Genome-wide CRISPR activation screening in senescent cells reveals SOX5 as a driver and therapeutic target of rejuvenation. Cell Stem Cell. 2025 Feb 06; 32(2):322-325. Jing Y, Jiang X, Ji Q, Wu Z, Wang W, Liu Z, Guillen-Garcia P, Esteban CR, Reddy P, Horvath S, Li J, Geng L, Hu Q, Wang S, Izpisua Belmonte JC, Ren J, Zhang W, Qu J, Liu GH. PMID: 39879990.
      View in: PubMed   Mentions: 2     Fields:    
    52. The androgen clock is an epigenetic predictor of long-term male hormone exposure. Proc Natl Acad Sci U S A. 2025 Jan 21; 122(3):e2420087121. Sugrue VJ, Prescott M, Glendining KA, Bond DM, Horvath S, Anderson GM, Garratt M, Campbell RE, Hore TA. PMID: 39805019; PMCID: PMC11760496.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    53. Epigenetic ageing clocks: statistical methods and emerging computational challenges. Nat Rev Genet. 2025 May; 26(5):350-368. Teschendorff AE, Horvath S. PMID: 39806006.
      View in: PubMed   Mentions: 66     Fields:    Translation:HumansAnimals
    54. The protein cargo of extracellular vesicles correlates with the epigenetic aging clock of exercise sensitive DNAmFitAge. Biogerontology. 2025 01 08; 26(1):35. György B, Szatmári R, Ditrói T, Torma F, Pálóczi K, Balbisi M, Visnovitz T, Koltai E, Nagy P, Buzás EI, Horvath S, Radák Z. PMID: 39775340; PMCID: PMC11711255.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
    55. Histone mark age of human tissues and cell types. Sci Adv. 2025 01 03; 11(1):eadk9373. de Lima Camillo LP, Asif MH, Horvath S, Larschan E, Singh R. PMID: 39742485; PMCID: PMC11691649.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansCells
    56. Loss of H3K9 trimethylation leads to premature aging. Res Sq. 2024 Dec 16. Mrabti C, Yang N, Desdín-Micó G, Alonso-Calleja A, Vílchez-Acosta A, Pico S, Parras A, Piao Y, Schoenfeldt L, Luo S, Haghani A, Brooke RT, Maza MDC, Branchina C, Bignon Y, Maroun CY, von Meyenn F, Naveiras O, Horvath S, Sen P, Ocampo A. PMID: 39764087; PMCID: PMC11702797.
      View in: PubMed   Mentions:
    57. Quantification of Epigenetic Aging in Public Health. Annu Rev Public Health. 2025 04; 46(1):91-110. Kusters CDJ, Horvath S. PMID: 39681336; PMCID: PMC12180540.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCellsPHPublic Health
    58. Slowed epigenetic aging in Olympic champions compared to non-champions. Geroscience. 2025 04; 47(2):2555-2565. Radák Z, Aczél D, Fejes I, Mozaffaritabar S, Pavlik G, Komka Z, Balogh L, Babszki Z, Babszki G, Koltai E, McGreevy KM, Gordevicius J, Horvath S, Kerepesi C. PMID: 39601999; PMCID: PMC11978583.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCells
    59. Corrigendum to Grandparents' educational attainment is associated with grandchildren's epigenetic-based age acceleration in the National Growth and Health Study [Soc. Sci. Med. 355 (2024) 117142]. Soc Sci Med. 2024 Nov; 361:117373. Surachman A, Hamlat E, Zannas AS, Horvath S, Laraia B, Epel E. PMID: 39361999.
      View in: PubMed   Mentions:    Fields:    
    60. AESurv: autoencoder survival analysis for accurate early prediction of coronary heart disease. Brief Bioinform. 2024 Sep 23; 25(6). Shen Y, Domingo-Relloso A, Kupsco A, Kioumourtzoglou MA, Tellez-Plaza M, Umans JG, Fretts AM, Zhang Y, Schnatz PF, Casanova R, Martin LW, Horvath S, Manson JE, Cole SA, Wu H, Whitsel EA, Baccarelli AA, Navas-Acien A, Gao F. PMID: 39323093; PMCID: PMC11424508.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    61. Challenges and recommendations for the translation of biomarkers of aging. Nat Aging. 2024 Oct; 4(10):1372-1383. Biomarkers of Aging Consortium, Herzog CMS, Goeminne LJE, Poganik JR, Barzilai N, Belsky DW, Betts-LaCroix J, Chen BH, Chen M, Cohen AA, Cummings SR, Fedichev PO, Ferrucci L, Fleming A, Fortney K, Furman D, Gorbunova V, Higgins-Chen A, Hood L, Horvath S, Justice JN, Kiel DP, Kuchel GA, Lasky-Su J, LeBrasseur NK, Maier AB, Schilling B, Sebastiano V, Slagboom PE, Snyder MP, Verdin E, Widschwendter M, Zhavoronkov A, Moqri M, Gladyshev VN. PMID: 39285015; PMCID: PMC12262637.
      View in: PubMed   Mentions: 35     Fields:    Translation:Humans
    62. Fundamental equations linking methylation dynamics to maximum lifespan in mammals. Nat Commun. 2024 09 16; 15(1):8093. Horvath S, Zhang J, Haghani A, Lu AT, Fei Z. PMID: 39285199; PMCID: PMC11405513.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimalsCells
    63. Metformin decelerates aging clock in male monkeys. Cell. 2024 Oct 31; 187(22):6358-6378.e29. Yang Y, Lu X, Liu N, Ma S, Zhang H, Zhang Z, Yang K, Jiang M, Zheng Z, Qiao Y, Hu Q, Huang Y, Zhang Y, Xiong M, Liu L, Jiang X, Reddy P, Dong X, Xu F, Wang Q, Zhao Q, Lei J, Sun S, Jing Y, Li J, Cai Y, Fan Y, Yan K, Jing Y, Haghani A, Xing M, Zhang X, Zhu G, Song W, Horvath S, Rodriguez Esteban C, Song M, Wang S, Zhao G, Li W, Izpisua Belmonte JC, Qu J, Zhang W, Liu GH. PMID: 39270656.
      View in: PubMed   Mentions: 92     Fields:    Translation:AnimalsCells
    64. Dissecting the impact of differentiation stage, replicative history, and cell type composition on epigenetic clocks. Stem Cell Reports. 2024 09 10; 19(9):1242-1254. Gorelov R, Weiner A, Huebner A, Yagi M, Haghani A, Brooke R, Horvath S, Hochedlinger K. PMID: 39178844; PMCID: PMC11411293.
      View in: PubMed   Mentions: 5     Fields:    Translation:AnimalsCells
    65. Digitising the ageing process with epigenetic clocks. Lancet. 2024 08 03; 404(10451):423. Horvath S, Topol EJ. PMID: 39097382.
      View in: PubMed   Mentions: 5     Fields:    
    66. A methylation risk score for chronic kidney disease: a HyperGEN study. Sci Rep. 2024 08 01; 14(1):17757. Jones AC, Patki A, Srinivasasainagendra V, Hidalgo BA, Tiwari HK, Limdi NA, Armstrong ND, Chaudhary NS, Minniefield B, Absher D, Arnett DK, Lange LA, Lange EM, Young BA, Diamantidis CJ, Rich SS, Mychaleckyj JC, Rotter JI, Taylor KD, Kramer HJ, Tracy RP, Durda P, Kasela S, Lappalinen T, Liu Y, Johnson WC, Van Den Berg DJ, Franceschini N, Liu S, Mouton CP, Bhatti P, Horvath S, Whitsel EA, Irvin MR. PMID: 39085340; PMCID: PMC11291488.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCells
    67. Epigenetic aging studies of pair bonding in prairie voles. Sci Rep. 2024 07 29; 14(1):17439. Sailer LL, Haghani A, Zoller JA, Li CZ, Ophir AG, Horvath S. PMID: 39075111; PMCID: PMC11286801.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    68. Methylome-proteome integration after late-life voluntary exercise training reveals regulation and target information for improved skeletal muscle health. J Physiol. 2025 01; 603(1):211-237. Chambers TL, Dimet-Wiley A, Keeble AR, Haghani A, Lo WJ, Kang G, Brooke R, Horvath S, Fry CS, Watowich SJ, Wen Y, Murach KA. PMID: 39058663; PMCID: PMC11702923.
      View in: PubMed   Mentions: 11     Fields:    Translation:AnimalsCells
    69. Discovering the direct relations between nutrients and epigenetic ageing. J Nutr Health Aging. 2024 09; 28(9):100324. Grootswagers P, Bach D, Biemans Y, Behrouzi P, Horvath S, Kramer CS, Liu S, Manson JE, Shadyab AH, Stewart JD, Whitsel E, Yang B, de Groot L. PMID: 39067141; PMCID: PMC12880071.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    70. Loss of H3K9 trimethylation leads to premature aging. bioRxiv. 2024 Jul 24. Mrabti C, Yang N, Desdín-Micó G, Alonso-Calleja A, Vílchez-Acosta A, Pico S, Parras A, Piao Y, Schoenfeldt L, Luo S, Haghani A, Brooke R, Del Carmen Maza M, Branchina C, Maroun CY, von Meyenn F, Naveiras O, Horvath S, Sen P, Ocampo A. PMID: 39091811; PMCID: PMC11291141.
      View in: PubMed   Mentions: 6  
    71. Cognitive rejuvenation in old rats by hippocampal OSKM gene therapy. Geroscience. 2025 02; 47(1):809-823. Horvath S, Lacunza E, Mallat MC, Portiansky EL, Gallardo MD, Brooke RT, Chiavellini P, Pasquini DC, Girard M, Lehmann M, Yan Q, Lu AT, Haghani A, Gordevicius J, Abba M, Goya RG. PMID: 39037528; PMCID: PMC11872836.
      View in: PubMed   Mentions: 7     Fields:    Translation:AnimalsCells
    72. PRC2-AgeIndex as a universal biomarker of aging and rejuvenation. Nat Commun. 2024 07 16; 15(1):5956. Moqri M, Cipriano A, Simpson DJ, Rasouli S, Murty T, de Jong TA, Nachun D, de Sena Brandine G, Ying K, Tarkhov A, Aberg KA, van den Oord E, Zhou W, Smith A, Mackall C, Gladyshev VN, Horvath S, Snyder MP, Sebastiano V. PMID: 39009581; PMCID: PMC11250797.
      View in: PubMed   Mentions: 40     Fields:    Translation:HumansAnimalsCells
    73. Msh3 and Pms1 Set Neuronal CAG-repeat Migration Rate to Drive Selective Striatal and Cortical Pathogenesis in HD Mice. bioRxiv. 2024 Jul 15. Wang N, Zhang S, Langfelder P, Ramanathan L, Plascencia M, Gao F, Vaca R, Gu X, Deng L, Dionisio LE, Prasad BC, Vogt T, Horvath S, Aaronson JS, Rosinski J, Yang XW. PMID: 39026894; PMCID: PMC11257559.
      View in: PubMed   Mentions:
    74. Grandparents' educational attainment is associated with grandchildren's epigenetic-based age acceleration in the National Growth and Health Study. Soc Sci Med. 2024 08; 355:117142. Surachman A, Hamlat E, Zannas AS, Horvath S, Laraia B, Epel E. PMID: 39106784; PMCID: PMC11703522.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    75. Co-analysis of methylation platforms for signatures of biological aging in the domestic dog reveals previously unexplored confounding factors. Aging (Albany NY). 2024 07 09; 16(13):10724-10748. Armero AS, Buckley RM, Mboning L, Spatola GJ, Horvath S, Pellegrini M, Ostrander EA. PMID: 38985449; PMCID: PMC11272130.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    76. Epigenetic age acceleration is a distinctive trait of epithelioid sarcoma with potential therapeutic implications. Geroscience. 2024 10; 46(5):5203-5209. Haefliger S, Chervova O, Davies C, Loh C, Tirabosco R, Amary F, Pillay N, Horvath S, Beck S, Flanagan AM, Lyskjær I. PMID: 38879847; PMCID: PMC11336154.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    77. Associations of Epigenetic Age Estimators With Cognitive Function Trajectories in the Women's Health Initiative Memory Study. Neurology. 2024 07 09; 103(1):e209534. Nguyen S, McEvoy LK, Espeland MA, Whitsel EA, Lu A, Horvath S, Manson JE, Rapp SR, Shadyab AH. PMID: 38857479; PMCID: PMC11226313.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    78. Epigenetic predictors of species maximum life span and other life-history traits in mammals. Sci Adv. 2024 06 07; 10(23):eadm7273. Li CZ, Haghani A, Yan Q, Lu AT, Zhang J, Fei Z, Ernst J, Yang XW, Gladyshev VN, Robeck TR, Chavez AS, Cook JA, Dunnum JL, Raj K, Seluanov A, Gorbunova V, Horvath S. PMID: 38848365; PMCID: PMC11160467.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansAnimalsCells
    79. A case-control study: epigenetic age acceleration in psoriasis. Arch Dermatol Res. 2024 Jun 07; 316(7):340. Macit B, Ragi SD, Moseley I, Molino J, McGeary JE, Horvath S, Qureshi A, Reginato AM, Cho E. PMID: 38847964.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
    80. Relationships of depression and antidepressant use with epigenetic age acceleration and all-cause mortality among postmenopausal women. Aging (Albany NY). 2024 05 27; 16(10):8446-8471. Beydoun MA, Beydoun HA, Ashe J, Georgescu MF, Horvath S, Lu A, Zannas AS, Shadyab AH, Jung SY, Wassertheil-Smoller S, Casanova R, Zonderman AB, Brunner RL. PMID: 38809417; PMCID: PMC11164525.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCells
    81. Effects of highly active antiretroviral therapy initiation on epigenomic DNA methylation in persons living with HIV. Front Bioinform. 2024; 4:1357889. Zhang J, Sehl ME, Shih R, Breen EC, Li F, Lu AT, Bream JH, Duggal P, Martinson J, Wolinsky SM, Martinez-Maza O, Ramirez CM, Horvath S, Jamieson BD. PMID: 38855142; PMCID: PMC11157437.
      View in: PubMed   Mentions: 3  
    82. Decreased but persistent epigenetic age acceleration is associated with changes in T-cell subsets after initiation of highly active antiretroviral therapy in persons living with HIV. Front Bioinform. 2024; 4:1356509. Sehl ME, Breen EC, Shih R, Li F, Zhang J, Langfelder P, Horvath S, Bream JH, Duggal P, Martinson J, Wolinsky SM, Martinez-Maza O, Ramirez CM, Jamieson BD. PMID: 38855141; PMCID: PMC11157435.
      View in: PubMed   Mentions: 1  
    83. Identifying the relation between food groups and biological ageing: a data-driven approach. Age Ageing. 2024 05 11; 53(Suppl 2):ii20-ii29. Biemans Y, Bach D, Behrouzi P, Horvath S, Kramer CS, Liu S, Manson JE, Shadyab AH, Stewart J, Whitsel EA, Yang B, de Groot L, Grootswagers P. PMID: 38745494; PMCID: PMC11094402.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCells
    84. MammalMethylClock R package: software for DNA methylation-based epigenetic clocks in mammals. Bioinformatics. 2024 05 02; 40(5). Zoller J, Horvath S. PMID: 38656974; PMCID: PMC11091737.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansAnimalsCells
    85. Young Plasma Rejuvenates Blood DNA Methylation Profile, Extends Mean Lifespan, and Improves Physical Appearance in Old Rats. J Gerontol A Biol Sci Med Sci. 2024 05 01; 79(5). Chiavellini P, Lehmann M, Gallardo MD, Mallat MC, Pasquini DC, Zoller JA, Gordevicius J, Girard M, Lacunza E, Herenu CB, Horvath S, Goya RG. PMID: 38430547; PMCID: PMC11020299.
      View in: PubMed   Mentions: 5     Fields:    Translation:AnimalsCells
    86. Atherosclerotic Plaque Epigenetic Age Acceleration Predicts a Poor Prognosis and Is Associated With Endothelial-to-Mesenchymal Transition in Humans. Arterioscler Thromb Vasc Biol. 2024 06; 44(6):1419-1431. Diez Benavente E, Hartman RJG, Sakkers TR, Wesseling M, Sloots Y, Slenders L, Boltjes A, Mol BM, de Borst GJ, de Kleijn DPV, Prange KHM, de Winther MPJ, Kuiper J, Civelek M, van der Laan SW, Horvath S, Onland-Moret NC, Mokry M, Pasterkamp G, den Ruijter HM. PMID: 38634280.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCells
    87. Meta-analysis of epigenetic aging in schizophrenia reveals multifaceted relationships with age, sex, illness duration, and polygenic risk. Clin Epigenetics. 2024 Apr 08; 16(1):53. Ori APS, Olde Loohuis LM, Guintivano J, Hannon E, Dempster E, St Clair D, Bass NJ, McQuillin A, Mill J, Sullivan PF, Kahn RS, Horvath S, Ophoff RA. PMID: 38589929; PMCID: PMC11003125.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansCells
    88. Correction to: Higher testosterone and testosterone/estradiol ratio in men are associated with decreased Pheno‑/GrimAge and DNA‑methylation based PAI1. Geroscience. 2024 Apr; 46(2):2791-2792. Kusters CDJ, Paul KC, Lu AT, Ferrucci L, Ritz BR, Binder AM, Horvath S. PMID: 37921956; PMCID: PMC10828359.
      View in: PubMed   Mentions:    Fields:    
    89. A torpor-like state (TLS) in mice slows blood epigenetic aging and prolongs healthspan. bioRxiv. 2024 Mar 25. Jayne L, Lavin-Peter A, Roessler J, Tyshkovskiy A, Antoszewski M, Ren E, Markovski A, Sun S, Yao H, Sankaran VG, Gladyshev VN, Brooke RT, Horvath S, Griffith EC, Hrvatin S. PMID: 38585858; PMCID: PMC10996477.
      View in: PubMed   Mentions:
    90. Intervention with metabolites emulating endogenous cell transitions accelerates muscle regeneration in young and aged mice. Cell Rep Med. 2024 Mar 19; 5(3):101449. Hernandez-Benitez R, Wang C, Shi L, Ouchi Y, Zhong C, Hishida T, Liao HK, Magill EA, Memczak S, Soligalla RD, Fresia C, Hatanaka F, Lamas V, Guillen I, Sahu S, Yamamoto M, Shao Y, Aguirre-Vazquez A, Nuñez Delicado E, Guillen P, Rodriguez Esteban C, Qu J, Reddy P, Horvath S, Liu GH, Magistretti P, Izpisua Belmonte JC. PMID: 38508141; PMCID: PMC10983034.
      View in: PubMed   Mentions: 5     Fields:    Translation:AnimalsCells
    91. Epigenetic aging of human blood cells is influenced by the age of the host body. Aging Cell. 2024 05; 23(5):e14112. Holland P, Istre M, Ali MM, Gedde-Dahl T, Buechner J, Wildhagen M, Brunvoll SH, Horvath S, Matsuyama S, Dahl JA, Stölzel F, Søraas A. PMID: 38439206; PMCID: PMC11113269.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCells
    92. Liver-derived plasminogen mediates muscle stem cell expansion during caloric restriction through the plasminogen receptor Plg-RKT. Cell Rep. 2024 03 26; 43(3):113881. Bareja A, Lee DE, Ho T, Waitt G, McKay LH, Hannou SA, Orenduff MC, McGreevy KM, Binder A, Ryan CP, Soderblom EJ, Belsky DW, Ferrucci L, Das JK, Banskota N, Kraus VB, Huebner JL, Kraus WE, Huffman KM, Baht GS, Horvath S, Parmer RJ, Miles LA, White JP. PMID: 38442019; PMCID: PMC11075744.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimals
    93. Alterations of the gut microbiome are associated with epigenetic age acceleration and physical fitness. Aging Cell. 2024 04; 23(4):e14101. Torma F, Kerepesi C, Jókai M, Babszki G, Koltai E, Ligeti B, Kalcsevszki R, McGreevy KM, Horvath S, Radák Z. PMID: 38414315; PMCID: PMC11019127.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansCells
    94. Validation of biomarkers of aging. Nat Med. 2024 02; 30(2):360-372. Moqri M, Herzog C, Poganik JR, Ying K, Justice JN, Belsky DW, Higgins-Chen AT, Chen BH, Cohen AA, Fuellen G, Hägg S, Marioni RE, Widschwendter M, Fortney K, Fedichev PO, Zhavoronkov A, Barzilai N, Lasky-Su J, Kiel DP, Kennedy BK, Cummings S, Slagboom PE, Verdin E, Maier AB, Sebastiano V, Snyder MP, Gladyshev VN, Horvath S, Ferrucci L. PMID: 38355974; PMCID: PMC11090477.
      View in: PubMed   Mentions: 154     Fields:    
    95. Initiation phase cellular reprogramming ameliorates DNA damage in the ERCC1 mouse model of premature aging. Front Aging. 2023; 4:1323194. Paine PT, Rechsteiner C, Morandini F, Desdín-Micó G, Mrabti C, Parras A, Haghani A, Brooke R, Horvath S, Seluanov A, Gorbunova V, Ocampo A. PMID: 38322248; PMCID: PMC10844398.
      View in: PubMed   Mentions: 5  
    96. Causality-enriched epigenetic age uncouples damage and adaptation. Nat Aging. 2024 Feb; 4(2):231-246. Ying K, Liu H, Tarkhov AE, Sadler MC, Lu AT, Moqri M, Horvath S, Kutalik Z, Shen X, Gladyshev VN. PMID: 38243142; PMCID: PMC11070280.
      View in: PubMed   Mentions: 100     Fields:    Translation:Cells
    97. Diet Quality and Epigenetic Aging in the Women's Health Initiative. J Acad Nutr Diet. 2024 Nov; 124(11):1419-1430.e3. Reynolds LM, Houston DK, Skiba MB, Whitsel EA, Stewart JD, Li Y, Zannas AS, Assimes TL, Horvath S, Bhatti P, Baccarelli AA, Tooze JA, Vitolins MZ. PMID: 38215906; PMCID: PMC11236955.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansCells
    98. DNA repair-deficient premature aging models display accelerated epigenetic age. Aging Cell. 2024 02; 23(2):e14058. Perez K, Parras A, Picó S, Rechsteiner C, Haghani A, Brooke R, Mrabti C, Schoenfeldt L, Horvath S, Ocampo A. PMID: 38140713; PMCID: PMC10861193.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansAnimalsCells
    99. The Association of Epigenetic Age Acceleration and Multimorbidity at Age 90 in the Women's Health Initiative. J Gerontol A Biol Sci Med Sci. 2023 12 01; 78(12):2274-2281. Jain P, Binder A, Chen B, Parada H, Gallo LC, Alcaraz J, Horvath S, Bhatti P, Whitsel EA, Jordahl K, Baccarelli AA, Hou L, Stewart JD, Li Y, LaMonte MJ, Manson JE, LaCroix AZ. PMID: 36107798; PMCID: PMC10692424.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansCells
    100. Pleiotropic influence of DNA methylation QTLs on physiological and ageing traits. Epigenetics. 2023 12; 18(1):2252631. Mozhui K, Kim H, Villani F, Haghani A, Sen S, Horvath S. PMID: 37691384; PMCID: PMC10496549.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimalsCells
    101. Cross-species and tissue imputation of species-level DNA methylation samples across mammalian species. bioRxiv. 2023 Nov 27. Maciejewski E, Horvath S, Ernst J. PMID: 38076978; PMCID: PMC10705269.
      View in: PubMed   Mentions:
    102. In vivo reprogramming leads to premature death linked to hepatic and intestinal failure. Nat Aging. 2023 12; 3(12):1509-1520. Parras A, Vílchez-Acosta A, Desdín-Micó G, Picó S, Mrabti C, Montenegro-Borbolla E, Maroun CY, Haghani A, Brooke R, Del Carmen Maza M, Rechsteiner C, Battiston F, Branchina C, Perez K, Horvath S, Bertelli C, Sempoux C, Ocampo A. PMID: 38012287.
      View in: PubMed   Mentions: 22     Fields:    Translation:Animals
    103. Author Correction: Universal DNA methylation age across mammalian tissues. Nat Aging. 2023 Nov; 3(11):1462. Lu AT, Fei Z, Haghani A, Robeck TR, Zoller JA, Li CZ, Lowe R, Yan Q, Zhang J, Vu H, Ablaeva J, Acosta-Rodriguez VA, Adams DM, Almunia J, Aloysius A, Ardehali R, Arneson A, Baker CS, Banks G, Belov K, Bennett NC, Black P, Blumstein DT, Bors EK, Breeze CE, Brooke RT, Brown JL, Carter GG, Caulton A, Cavin JM, Chakrabarti L, Chatzistamou I, Chen H, Cheng K, Chiavellini P, Choi OW, Clarke SM, Cooper LN, Cossette ML, Day J, DeYoung J, DiRocco S, Dold C, Ehmke EE, Emmons CK, Emmrich S, Erbay E, Erlacher-Reid C, Faulkes CG, Ferguson SH, Finno CJ, Flower JE, Gaillard JM, Garde E, Gerber L, Gladyshev VN, Gorbunova V, Goya RG, Grant MJ, Green CB, Hales EN, Hanson MB, Hart DW, Haulena M, Herrick K, Hogan AN, Hogg CJ, Hore TA, Huang T, Izpisua Belmonte JC, Jasinska AJ, Jones G, Jourdain E, Kashpur O, Katcher H, Katsumata E, Kaza V, Kiaris H, Kobor MS, Kordowitzki P, Koski WR, Krützen M, Kwon SB, Larison B, Lee SG, Lehmann M, Lemaitre JF, Levine AJ, Li C, Li X, Lim AR, Lin DTS, Lindemann DM, Little TJ, Macoretta N, Maddox D, Matkin CO, Mattison JA, McClure M, Mergl J, Meudt JJ, Montano GA, Mozhui K, Munshi-South J, Naderi A, Nagy M, Narayan P, Nathanielsz PW, Nguyen NB, Niehrs C, O'Brien JK, O'Tierney Ginn P, Odom DT, Ophir AG, Osborn S, Ostrander EA, Parsons KM, Paul KC, Pellegrini M, Peters KJ, Pedersen AB, Petersen JL, Pietersen DW, Pinho GM, Plassais J, Poganik JR, Prado NA, Reddy P, Rey B, Ritz BR, Robbins J, Rodriguez M, Russell J, Rydkina E, Sailer LL, Salmon AB, Sanghavi A, Schachtschneider KM, Schmitt D, Schmitt T, Schomacher L, Schook LB, Sears KE, Seifert AW, Seluanov A, Shafer ABA, Shanmuganayagam D, Shindyapina AV, Simmons M, Singh K, Sinha I, Slone J, Snell RG, Soltanmaohammadi E, Spangler ML, Spriggs MC, Staggs L, Stedman N, Steinman KJ, Stewart DT, Sugrue VJ, Szladovits B, Takahashi JS, Takasugi M, Teeling EC, Thompson MJ, Van Bonn B, Vernes SC, Villar D, Vinters HV, Wallingford MC, Wang N, Wayne RK, Wilkinson GS, Williams CK, Williams RW, Yang XW, Yao M, Young BG, Zhang B, Zhang Z, Zhao P, Zhao Y, Zhou W, Zimmermann J, Ernst J, Raj K, Horvath S. PMID: 37674040; PMCID: PMC10645586.
      View in: PubMed   Mentions: 4     Fields:    
    104. Reversal of biological age in multiple rat organs by young porcine plasma fraction. Geroscience. 2024 02; 46(1):367-394. Horvath S, Singh K, Raj K, Khairnar SI, Sanghavi A, Shrivastava A, Zoller JA, Li CZ, Herenu CB, Canatelli-Mallat M, Lehmann M, Habazin S, Novokmet M, Vuckovic F, Solberg Woods LC, Martinez AG, Wang T, Chiavellini P, Levine AJ, Chen H, Brooke RT, Gordevicius J, Lauc G, Goya RG, Katcher HL. PMID: 37875652; PMCID: PMC10828479.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansAnimals
    105. Correction: Castration delays epigenetic aging and feminizes DNA methylation at androgen-regulated loci. Elife. 2023 Oct 13; 12. Sugrue VJ, Zoller JA, Narayan P, Lu AT, Ortega-Recalde OJ, Grant MJ, Bawden CS, Rudiger SR, Haghani A, Bond DM, Hore RR, Garratt M, Sears KE, Wang N, Yang XW, Snell RG, Hore TA, Horvath S. PMID: 37831065; PMCID: PMC10575626.
      View in: PubMed   Mentions: 1     Fields:    
    106. Genome-wide CRISPR activation screening in senescent cells reveals SOX5 as a driver and therapeutic target of rejuvenation. Cell Stem Cell. 2023 11 02; 30(11):1452-1471.e10. Jing Y, Jiang X, Ji Q, Wu Z, Wang W, Liu Z, Guillen-Garcia P, Esteban CR, Reddy P, Horvath S, Li J, Geng L, Hu Q, Wang S, Belmonte JCI, Ren J, Zhang W, Qu J, Liu GH. PMID: 37832549.
      View in: PubMed   Mentions: 39     Fields:    Translation:HumansAnimalsCells
    107. Using epigenetic clocks to investigate changes in the age structure of critically endangered Māui dolphins. Ecol Evol. 2023 Oct; 13(10):e10562. Hernandez KM, O'Neill KB, Bors EK, Steel D, Zoller JA, Constantine R, Horvath S, Baker CS. PMID: 37780090; PMCID: PMC10534197.
      View in: PubMed   Mentions: 4  
    108. Epigenomic signature of accelerated ageing in progeroid Cockayne syndrome. Aging Cell. 2023 10; 22(10):e13959. Crochemore C, Chica C, Garagnani P, Lattanzi G, Horvath S, Sarasin A, Franceschi C, Bacalini MG, Ricchetti M. PMID: 37688320; PMCID: PMC10577576.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
    109. Biomarkers of aging for the identification and evaluation of longevity interventions. Cell. 2023 08 31; 186(18):3758-3775. Moqri M, Herzog C, Poganik JR, Biomarkers of Aging Consortium, Justice J, Belsky DW, Higgins-Chen A, Moskalev A, Fuellen G, Cohen AA, Bautmans I, Widschwendter M, Ding J, Fleming A, Mannick J, Han JJ, Zhavoronkov A, Barzilai N, Kaeberlein M, Cummings S, Kennedy BK, Ferrucci L, Horvath S, Verdin E, Maier AB, Snyder MP, Sebastiano V, Gladyshev VN. PMID: 37657418; PMCID: PMC11088934.
      View in: PubMed   Mentions: 327     Fields:    Translation:Humans
    110. Bloom syndrome patients and mice display accelerated epigenetic aging. Aging Cell. 2023 10; 22(10):e13964. Lee J, Zhang J, Flanagan M, Martinez JA, Cunniff C, Kucine N, Lu AT, Haghani A, Gordevicius J, Horvath S, Chang VY. PMID: 37594403; PMCID: PMC10577546.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansAnimalsCells
    111. Associations between cardiorespiratory fitness and lifestyle-related factors with DNA methylation-based ageing clocks in older men: WASEDA'S Health Study. Aging Cell. 2024 01; 23(1):e13960. Kawamura T, Radak Z, Tabata H, Akiyama H, Nakamura N, Kawakami R, Ito T, Usui C, Jokai M, Torma F, Kim HK, Miyachi M, Torii S, Suzuki K, Ishii K, Sakamoto S, Oka K, Higuchi M, Muraoka I, McGreevy KM, Horvath S, Tanisawa K. PMID: 37584423; PMCID: PMC10776125.
      View in: PubMed   Mentions: 23     Fields:    Translation:HumansCells
    112. DNA methylation networks underlying mammalian traits. Science. 2023 08 11; 381(6658):eabq5693. Haghani A, Li CZ, Robeck TR, Zhang J, Lu AT, Ablaeva J, Acosta-Rodríguez VA, Adams DM, Alagaili AN, Almunia J, Aloysius A, Amor NMS, Ardehali R, Arneson A, Baker CS, Banks G, Belov K, Bennett NC, Black P, Blumstein DT, Bors EK, Breeze CE, Brooke RT, Brown JL, Carter G, Caulton A, Cavin JM, Chakrabarti L, Chatzistamou I, Chavez AS, Chen H, Cheng K, Chiavellini P, Choi OW, Clarke S, Cook JA, Cooper LN, Cossette ML, Day J, DeYoung J, Dirocco S, Dold C, Dunnum JL, Ehmke EE, Emmons CK, Emmrich S, Erbay E, Erlacher-Reid C, Faulkes CG, Fei Z, Ferguson SH, Finno CJ, Flower JE, Gaillard JM, Garde E, Gerber L, Gladyshev VN, Goya RG, Grant MJ, Green CB, Hanson MB, Hart DW, Haulena M, Herrick K, Hogan AN, Hogg CJ, Hore TA, Huang T, Izpisua Belmonte JC, Jasinska AJ, Jones G, Jourdain E, Kashpur O, Katcher H, Katsumata E, Kaza V, Kiaris H, Kobor MS, Kordowitzki P, Koski WR, Krützen M, Kwon SB, Larison B, Lee SG, Lehmann M, Lemaître JF, Levine AJ, Li X, Li C, Lim AR, Lin DTS, Lindemann DM, Liphardt SW, Little TJ, Macoretta N, Maddox D, Matkin CO, Mattison JA, McClure M, Mergl J, Meudt JJ, Montano GA, Mozhui K, Munshi-South J, Murphy WJ, Naderi A, Nagy M, Narayan P, Nathanielsz PW, Nguyen NB, Niehrs C, Nyamsuren B, O'Brien JK, Ginn PO, Odom DT, Ophir AG, Osborn S, Ostrander EA, Parsons KM, Paul KC, Pedersen AB, Pellegrini M, Peters KJ, Petersen JL, Pietersen DW, Pinho GM, Plassais J, Poganik JR, Prado NA, Reddy P, Rey B, Ritz BR, Robbins J, Rodriguez M, Russell J, Rydkina E, Sailer LL, Salmon AB, Sanghavi A, Schachtschneider KM, Schmitt D, Schmitt T, Schomacher L, Schook LB, Sears KE, Seifert AW, Shafer ABA, Shindyapina AV, Simmons M, Singh K, Sinha I, Slone J, Snell RG, Soltanmohammadi E, Spangler ML, Spriggs M, Staggs L, Stedman N, Steinman KJ, Stewart DT, Sugrue VJ, Szladovits B, Takahashi JS, Takasugi M, Teeling EC, Thompson MJ, Van Bonn B, Vernes SC, Villar D, Vinters HV, Vu H, Wallingford MC, Wang N, Wilkinson GS, Williams RW, Yan Q, Yao M, Young BG, Zhang B, Zhang Z, Zhao Y, Zhao P, Zhou W, Zoller JA, Ernst J, Seluanov A, Gorbunova V, Yang XW, Raj K, Horvath S. PMID: 37561875; PMCID: PMC11180965.
      View in: PubMed   Mentions: 74     Fields:    Translation:HumansAnimalsCells
    113. Universal DNA methylation age across mammalian tissues. Nat Aging. 2023 09; 3(9):1144-1166. Lu AT, Fei Z, Haghani A, Robeck TR, Zoller JA, Li CZ, Lowe R, Yan Q, Zhang J, Vu H, Ablaeva J, Acosta-Rodriguez VA, Adams DM, Almunia J, Aloysius A, Ardehali R, Arneson A, Baker CS, Banks G, Belov K, Bennett NC, Black P, Blumstein DT, Bors EK, Breeze CE, Brooke RT, Brown JL, Carter GG, Caulton A, Cavin JM, Chakrabarti L, Chatzistamou I, Chen H, Cheng K, Chiavellini P, Choi OW, Clarke SM, Cooper LN, Cossette ML, Day J, DeYoung J, DiRocco S, Dold C, Ehmke EE, Emmons CK, Emmrich S, Erbay E, Erlacher-Reid C, Faulkes CG, Ferguson SH, Finno CJ, Flower JE, Gaillard JM, Garde E, Gerber L, Gladyshev VN, Gorbunova V, Goya RG, Grant MJ, Green CB, Hales EN, Hanson MB, Hart DW, Haulena M, Herrick K, Hogan AN, Hogg CJ, Hore TA, Huang T, Izpisua Belmonte JC, Jasinska AJ, Jones G, Jourdain E, Kashpur O, Katcher H, Katsumata E, Kaza V, Kiaris H, Kobor MS, Kordowitzki P, Koski WR, Krützen M, Kwon SB, Larison B, Lee SG, Lehmann M, Lemaitre JF, Levine AJ, Li C, Li X, Lim AR, Lin DTS, Lindemann DM, Little TJ, Macoretta N, Maddox D, Matkin CO, Mattison JA, McClure M, Mergl J, Meudt JJ, Montano GA, Mozhui K, Munshi-South J, Naderi A, Nagy M, Narayan P, Nathanielsz PW, Nguyen NB, Niehrs C, O'Brien JK, O'Tierney Ginn P, Odom DT, Ophir AG, Osborn S, Ostrander EA, Parsons KM, Paul KC, Pellegrini M, Peters KJ, Pedersen AB, Petersen JL, Pietersen DW, Pinho GM, Plassais J, Poganik JR, Prado NA, Reddy P, Rey B, Ritz BR, Robbins J, Rodriguez M, Russell J, Rydkina E, Sailer LL, Salmon AB, Sanghavi A, Schachtschneider KM, Schmitt D, Schmitt T, Schomacher L, Schook LB, Sears KE, Seifert AW, Seluanov A, Shafer ABA, Shanmuganayagam D, Shindyapina AV, Simmons M, Singh K, Sinha I, Slone J, Snell RG, Soltanmaohammadi E, Spangler ML, Spriggs MC, Staggs L, Stedman N, Steinman KJ, Stewart DT, Sugrue VJ, Szladovits B, Takahashi JS, Takasugi M, Teeling EC, Thompson MJ, Van Bonn B, Vernes SC, Villar D, Vinters HV, Wallingford MC, Wang N, Wayne RK, Wilkinson GS, Williams CK, Williams RW, Yang XW, Yao M, Young BG, Zhang B, Zhang Z, Zhao P, Zhao Y, Zhou W, Zimmermann J, Ernst J, Raj K, Horvath S. PMID: 37563227; PMCID: PMC10501909.
      View in: PubMed   Mentions: 227     Fields:    Translation:HumansAnimalsCells
    114. Reversal of Biological Age in Multiple Rat Organs by Young Porcine Plasma Fraction. bioRxiv. 2023 Aug 07. Horvath S, Singh K, Raj K, Khairnar S, Sanghavi A, Shrivastava A, Zoller JA, Li CZ, Herenu CB, Canatelli-Mallat M, Lehmann M, Habazin S, Novokmet M, Vuckovic F, Woods LCS, Martinez AG, Wang T, Chiavellini P, Levine AJ, Chen H, Brooke RT, Gordevicius J, Lauc G, Goya RG, Katcher HL. PMID: 37609328; PMCID: PMC10441355.
      View in: PubMed   Mentions:
    115. Multivariate genome-wide analysis of aging-related traits identifies novel loci and new drug targets for healthy aging. Nat Aging. 2023 08; 3(8):1020-1035. Rosoff DB, Mavromatis LA, Bell AS, Wagner J, Jung J, Marioni RE, Davey Smith G, Horvath S, Lohoff FW. PMID: 37550455; PMCID: PMC10432278.
      View in: PubMed   Mentions: 39     Fields:    
    116. Identification of novel hypermethylated or hypomethylated CpG sites and genes associated with anthracycline-induced cardiomyopathy. Sci Rep. 2023 08 04; 13(1):12683. Singh P, Zhou L, Shah DA, Cejas RB, Crossman DK, Jouni M, Magdy T, Wang X, Sharafeldin N, Hageman L, McKenna DE, Horvath S, Armenian SH, Balis FM, Hawkins DS, Keller FG, Hudson MM, Neglia JP, Ritchey AK, Ginsberg JP, Landier W, Burridge PW, Bhatia S. PMID: 37542143; PMCID: PMC10403495.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansCells
    117. Higher testosterone and testosterone/estradiol ratio in men are associated with better epigenetic estimators of mortality risk. medRxiv. 2023 Jul 30. Kusters CD, Paul KC, Lu AT, Ferrucci L, Ritz BR, Binder AM, Horvath S. PMID: 36865294; PMCID: PMC9980235.
      View in: PubMed   Mentions:
    118. Multi-omic rejuvenation and life span extension on exposure to youthful circulation. Nat Aging. 2023 08; 3(8):948-964. Zhang B, Lee DE, Trapp A, Tyshkovskiy A, Lu AT, Bareja A, Kerepesi C, McKay LK, Shindyapina AV, Dmitriev SE, Baht GS, Horvath S, Gladyshev VN, White JP. PMID: 37500973; PMCID: PMC11095548.
      View in: PubMed   Mentions: 62     Fields:    Translation:Animals
    119. Pan-primate studies of age and sex. Geroscience. 2023 12; 45(6):3187-3209. Horvath S, Haghani A, Zoller JA, Lu AT, Ernst J, Pellegrini M, Jasinska AJ, Mattison JA, Salmon AB, Raj K, Horvath M, Paul KC, Ritz BR, Robeck TR, Spriggs M, Ehmke EE, Jenkins S, Li C, Nathanielsz PW. PMID: 37493860; PMCID: PMC10643767.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansAnimalsCells
    120. Erratum: Accelerated aging with HIV begins at the time of initial HIV infection. iScience. 2023 Aug 18; 26(8):107381. Breen EC, Sehl ME, Shih R, Langfelder P, Wang R, Horvath S, Bream JH, Duggal P, Martinson J, Wolinsky SM, Martínez-Maza O, Ramirez CM, Jamieson BD. PMID: 37520728; PMCID: PMC10371831.
      View in: PubMed   Mentions: 1  
    121. Higher testosterone and testosterone/estradiol ratio in men are associated with decreased Pheno-/GrimAge and DNA-methylation based PAI1. Geroscience. 2024 02; 46(1):1053-1069. Kusters CDJ, Paul KC, Lu AT, Ferruci L, Ritz BR, Binder AM, Horvath S. PMID: 37369886; PMCID: PMC10828310.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    122. Early life adversity predicts an accelerated cellular aging phenotype through early timing of puberty. Psychol Med. 2023 12; 53(16):7720-7728. Hamlat EJ, Neilands TB, Laraia B, Zhang J, Lu AT, Lin J, Horvath S, Epel ES. PMID: 37325994; PMCID: PMC11131158.
      View in: PubMed   Mentions: 15     Fields:    Translation:Humans
    123. Cellular allostatic load is linked to increased energy expenditure and accelerated biological aging. Psychoneuroendocrinology. 2023 09; 155:106322. Bobba-Alves N, Sturm G, Lin J, Ware SA, Karan KR, Monzel AS, Bris C, Procaccio V, Lenaers G, Higgins-Chen A, Levine M, Horvath S, Santhanam BS, Kaufman BA, Hirano M, Epel E, Picard M. PMID: 37423094; PMCID: PMC10528419.
      View in: PubMed   Mentions: 40     Fields:    Translation:Humans
    124. DNA methylation clocks for clawed frogs reveal evolutionary conservation of epigenetic aging. Geroscience. 2024 02; 46(1):945-960. Zoller JA, Parasyraki E, Lu AT, Haghani A, Niehrs C, Horvath S. PMID: 37270437; PMCID: PMC10828168.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansAnimalsCells
    125. DNA methylation clock DNAmFitAge shows regular exercise is associated with slower aging and systemic adaptation. Geroscience. 2023 10; 45(5):2805-2817. Jokai M, Torma F, McGreevy KM, Koltai E, Bori Z, Babszki G, Bakonyi P, Gombos Z, Gyorgy B, Aczel D, Toth L, Osvath P, Fridvalszky M, Teglas T, Posa A, Kujach S, Olek R, Kawamura T, Seki Y, Suzuki K, Tanisawa K, Goto S, Kerepesi C, Boldogh I, Ba X, Davies KJA, Horvath S, Radak Z. PMID: 37209203; PMCID: PMC10643800.
      View in: PubMed   Mentions: 32     Fields:    Translation:HumansCells
    126. Accelerated epigenetic aging and DNA methylation alterations in Berardinelli-Seip congenital lipodystrophy. Hum Mol Genet. 2023 05 18; 32(11):1826-1835. Qannan A, Bejaoui Y, Izadi M, Yousri NA, Razzaq A, Christiansen C, Martin GM, Bell JT, Horvath S, Oshima J, Megarbane A, Ericsson J, Pourkarimi E, El Hajj N. PMID: 36715159; PMCID: PMC10196674.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCells
    127. Persistent accelerated epigenetic ageing in a longitudinal cohort of vertically infected HIV-positive adolescents. J Neurovirol. 2023 06; 29(3):272-282. Heany SJ, Levine AJ, Lesosky M, Phillips N, Fouche JP, Myer L, Zar HJ, Stein DJ, Horvath S, Hoare J. PMID: 37179258; PMCID: PMC10404174.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    128. Biological age is increased by stress and restored upon recovery. Cell Metab. 2023 05 02; 35(5):807-820.e5. Poganik JR, Zhang B, Baht GS, Tyshkovskiy A, Deik A, Kerepesi C, Yim SH, Lu AT, Haghani A, Gong T, Hedman AM, Andolf E, Pershagen G, Almqvist C, Clish CB, Horvath S, White JP, Gladyshev VN. PMID: 37086720; PMCID: PMC11055493.
      View in: PubMed   Mentions: 105     Fields:    Translation:HumansAnimals
    129. DNA methylation-based biomarkers for ageing long-lived cetaceans. Mol Ecol Resour. 2023 Aug; 23(6):1241-1256. Parsons KM, Haghani A, Zoller JA, Lu AT, Fei Z, Ferguson SH, Garde E, Hanson MB, Emmons CK, Matkin CO, Young BG, Koski WR, Horvath S. PMID: 36994812.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansAnimalsCells
    130. Multi-tissue DNA methylation aging clocks for sea lions, walruses and seals. Commun Biol. 2023 04 01; 6(1):359. Robeck TR, Haghani A, Fei Z, Lindemann DM, Russell J, Herrick KES, Montano G, Steinman KJ, Katsumata E, Zoller JA, Horvath S. PMID: 37005462; PMCID: PMC10067968.
      View in: PubMed   Mentions: 8  Translation:AnimalsCells
    131. DNA methylation and cardiovascular disease in humans: a systematic review and database of known CpG methylation sites. Clin Epigenetics. 2023 03 30; 15(1):56. Krolevets M, Cate VT, Prochaska JH, Schulz A, Rapp S, Tenzer S, Andrade-Navarro MA, Horvath S, Niehrs C, Wild PS. PMID: 36991458; PMCID: PMC10061871.
      View in: PubMed   Mentions: 39     Fields:    Translation:HumansCellsPHPublic Health
    132. DNA methylation age in paired tumor and adjacent normal breast tissue in Chinese women with breast cancer. Clin Epigenetics. 2023 03 30; 15(1):55. Koka H, Bodelon C, Horvath S, Lee PMY, Wang D, Song L, Zhang T, Hurson AN, Guida JL, Zhu B, Bailey-Whyte M, Wang F, Wu C, Tsang KH, Tsoi YK, Chan WC, Law SH, Hung RKW, Tse GM, Yuen KK, Karlins E, Jones K, Vogt A, Zhu B, Hutchinson A, Hicks B, Garcia-Closas M, Chanock S, Barnholtz-Sloan J, Tse LA, Yang XR. PMID: 36991516; PMCID: PMC10062015.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCells
    133. Centenarian clocks: epigenetic clocks for validating claims of exceptional longevity. Geroscience. 2023 06; 45(3):1817-1835. Dec E, Clement J, Cheng K, Church GM, Fossel MB, Rehkopf DH, Rosero-Bixby L, Kobor MS, Lin DT, Lu AT, Fei Z, Guo W, Chew YC, Yang X, Putra SED, Reiner AP, Correa A, Vilalta A, Pirazzini C, Passarino G, Monti D, Arosio B, Garagnani P, Franceschi C, Horvath S. PMID: 36964402; PMCID: PMC10400760.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansCells
    134. Refining epigenetic prediction of chronological and biological age. Genome Med. 2023 02 28; 15(1):12. Bernabeu E, McCartney DL, Gadd DA, Hillary RF, Lu AT, Murphy L, Wrobel N, Campbell A, Harris SE, Liewald D, Hayward C, Sudlow C, Cox SR, Evans KL, Horvath S, McIntosh AM, Robinson MR, Vallejos CA, Marioni RE. PMID: 36855161; PMCID: PMC9976489.
      View in: PubMed   Mentions: 69     Fields:    Translation:Humans
    135. DNAmFitAge: biological age indicator incorporating physical fitness. Aging (Albany NY). 2023 02 22; 15(10):3904-3938. McGreevy KM, Radak Z, Torma F, Jokai M, Lu AT, Belsky DW, Binder A, Marioni RE, Ferrucci L, Pospiech E, Branicki W, Ossowski A, Sitek A, Spólnicka M, Raffield LM, Reiner AP, Cox S, Kobor M, Corcoran DL, Horvath S. PMID: 36812475; PMCID: PMC10258016.
      View in: PubMed   Mentions: 56     Fields:    Translation:HumansCellsPHPublic Health
    136. The Circulating Level of Klotho Is Not Dependent upon Physical Fitness and Age-Associated Methylation Increases at the Promoter Region of the Klotho Gene. Genes (Basel). 2023 02 19; 14(2). Aczel D, Torma F, Jokai M, McGreevy K, Boros A, Seki Y, Boldogh I, Horvath S, Radak Z. PMID: 36833453; PMCID: PMC9957177.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCells
    137. Author Correction: Protein interaction network of alternatively spliced isoforms from brain links genetic risk factors for autism. Nat Commun. 2023 Feb 02; 14(1):569. Corominas R, Yang X, Lin GN, Kang S, Shen Y, Ghamsari L, Broly M, Rodriguez M, Tam S, Wanamaker SA, Fan C, Yi S, Tasan M, Lemmens I, Kuang X, Zhao N, Malhotra D, Michaelson JJ, Vacic V, Calderwood MA, Roth FP, Tavernier J, Horvath S, Salehi-Ashtiani K, Korkin D, Sebat J, Hill DE, Hao T, Vidal M, Iakoucheva LM. PMID: 36732511; PMCID: PMC9895433.
      View in: PubMed   Mentions: 1     Fields:    
    138. A molecular signature defining exercise adaptation with ageing and in vivo partial reprogramming in skeletal muscle. J Physiol. 2023 02; 601(4):763-782. Jones RG, Dimet-Wiley A, Haghani A, da Silva FM, Brightwell CR, Lim S, Khadgi S, Wen Y, Dungan CM, Brooke RT, Greene NP, Peterson CA, McCarthy JJ, Horvath S, Watowich SJ, Fry CS, Murach KA. PMID: 36533424; PMCID: PMC9987218.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansAnimalsCells
    139. Comparative epigenome analysis using Infinium DNA methylation BeadChips. Brief Bioinform. 2023 01 19; 24(1). Ding W, Kaur D, Horvath S, Zhou W. PMID: 36617464; PMCID: PMC10147478.
      View in: PubMed   Mentions: 20     Fields:    Translation:AnimalsCells
    140. Epigenome-wide meta-analysis of BMI in nine cohorts: Examining the utility of epigenetically predicted BMI. Am J Hum Genet. 2023 02 02; 110(2):273-283. Do WL, Sun D, Meeks K, Dugué PA, Demerath E, Guan W, Li S, Chen W, Milne R, Adeyemo A, Agyemang C, Nassir R, Manson JE, Shadyab AH, Hou L, Horvath S, Assimes TL, Bhatti P, Jordahl KM, Baccarelli AA, Smith AK, Staimez LR, Stein AD, Whitsel EA, Narayan KMV, Conneely KN. PMID: 36649705; PMCID: PMC9943731.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansCells
    141. STAT3 promotes a youthful epigenetic state in articular chondrocytes. Aging Cell. 2023 02; 22(2):e13773. Sarkar A, Liu NQ, Magallanes J, Tassey J, Lee S, Shkhyan R, Lee Y, Lu J, Ouyang Y, Tang H, Bian F, Tao L, Segil N, Ernst J, Lyons K, Horvath S, Evseenko D. PMID: 36638270; PMCID: PMC9924946.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansAnimalsCells
    142. OxPhos defects cause hypermetabolism and reduce lifespan in cells and in patients with mitochondrial diseases. Commun Biol. 2023 01 12; 6(1):22. Sturm G, Karan KR, Monzel AS, Santhanam B, Taivassalo T, Bris C, Ware SA, Cross M, Towheed A, Higgins-Chen A, McManus MJ, Cardenas A, Lin J, Epel ES, Rahman S, Vissing J, Grassi B, Levine M, Horvath S, Haller RG, Lenaers G, Wallace DC, St-Onge MP, Tavazoie S, Procaccio V, Kaufman BA, Seifert EL, Hirano M, Picard M. PMID: 36635485; PMCID: PMC9837150.
      View in: PubMed   Mentions: 78  Translation:HumansCells
    143. Alcohol consumption and epigenetic age acceleration in young adults. Aging (Albany NY). 2023 01 05; 15(2):371-395. Nannini DR, Joyce BT, Zheng Y, Gao T, Wang J, Liu L, Jacobs DR, Schreiner PJ, Liu C, Dai Q, Horvath S, Lu AT, Yaffe K, Greenland P, Lloyd-Jones DM, Hou L. PMID: 36622282; PMCID: PMC9925681.
      View in: PubMed   Mentions: 12     Fields:    Translation:Humans
    144. No strong association among epigenetic modifications by DNA methylation, telomere length, and physical fitness in biological aging. Biogerontology. 2023 04; 24(2):245-255. Seki Y, Aczel D, Torma F, Jokai M, Boros A, Suzuki K, Higuchi M, Tanisawa K, Boldogh I, Horvath S, Radak Z. PMID: 36592269; PMCID: PMC10006047.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansCells
    145. Hippocampal DNA Methylation, Epigenetic Age, and Spatial Memory Performance in Young and Old Rats. J Gerontol A Biol Sci Med Sci. 2022 12 29; 77(12):2387-2394. Chiavellini P, Lehmann M, Canatelli Mallat M, Zoller JA, Herenu CB, Morel GR, Horvath S, Goya RG. PMID: 35917578.
      View in: PubMed   Mentions: 7     Fields:    Translation:AnimalsCells
    146. An epigenetic DNA methylation clock for age estimates in Indo-Pacific bottlenose dolphins (Tursiops aduncus). Evol Appl. 2023 Jan; 16(1):126-133. Peters KJ, Gerber L, Scheu L, Cicciarella R, Zoller JA, Fei Z, Horvath S, Allen SJ, King SL, Connor RC, Rollins LA, Krützen M. PMID: 36699128; PMCID: PMC9850008.
      View in: PubMed   Mentions: 13  
    147. DNA methylation GrimAge version 2. Aging (Albany NY). 2022 12 14; 14(23):9484-9549. Lu AT, Binder AM, Zhang J, Yan Q, Reiner AP, Cox SR, Corley J, Harris SE, Kuo PL, Moore AZ, Bandinelli S, Stewart JD, Wang C, Hamlat EJ, Epel ES, Schwartz JD, Whitsel EA, Correa A, Ferrucci L, Marioni RE, Horvath S. PMID: 36516495; PMCID: PMC9792204.
      View in: PubMed   Mentions: 201     Fields:    Translation:HumansCells
    148. Epigenetic age provides insight into tissue origin in endometriosis. Sci Rep. 2022 12 08; 12(1):21281. Leap K, Yotova I, Horvath S, Martinez-Agosto JA. PMID: 36481772; PMCID: PMC9732286.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    149. A multi-omics longitudinal aging dataset in primary human fibroblasts with mitochondrial perturbations. Sci Data. 2022 12 03; 9(1):751. Sturm G, Monzel AS, Karan KR, Michelson J, Ware SA, Cardenas A, Lin J, Bris C, Santhanam B, Murphy MP, Levine ME, Horvath S, Belsky DW, Wang S, Procaccio V, Kaufman BA, Hirano M, Picard M. PMID: 36463290; PMCID: PMC9719499.
      View in: PubMed   Mentions: 27     Fields:    Translation:HumansCells
    150. The Blood DNA Methylation Clock GrimAge Is a Robust Surrogate for Airway Epithelia Aging. Biomedicines. 2022 Dec 01; 10(12). Hernandez Cordero AI, Yang CX, Li X, Yang J, Shaipanich T, MacIsaac JL, Lin DTS, Kobor MS, Horvath S, Man SFP, Sin DD, Leung JM. PMID: 36551848; PMCID: PMC9775434.
      View in: PubMed   Mentions: 8  
    151. Corrigendum to "Association of subjective social status with epigenetic aging among Black and White women" [Psychoneuroendocrinology, 141 (2022), 105748]. Psychoneuroendocrinology. 2023 Feb; 148:105978. Hamlat EJ, Adler NE, Laraia B, Surachman A, Lu AT, Zhang J, Horvath S, Epel ES. PMID: 36435663.
      View in: PubMed   Mentions:    Fields:    
    152. Stress induced aging in mouse eye. Aging Cell. 2022 Dec; 21(12):e13737. Xu Q, Rydz C, Nguyen Huu VA, Rocha L, Palomino La Torre C, Lee I, Cho W, Jabari M, Donello J, Lyon DC, Brooke RT, Horvath S, Weinreb RN, Ju WK, Foik A, Skowronska-Krawczyk D. PMID: 36397653; PMCID: PMC9741506.
      View in: PubMed   Mentions: 25     Fields:    Translation:AnimalsCells
    153. Marijuana use and DNA methylation-based biological age in young adults. Clin Epigenetics. 2022 10 26; 14(1):134. Nannini DR, Zheng Y, Joyce BT, Gao T, Liu L, Jacobs DR, Schreiner P, Liu C, Horvath S, Lu AT, Yaffe K, Sidney S, Greenland P, Lloyd-Jones DM, Hou L. PMID: 36289503; PMCID: PMC9609285.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCells
    154. Significant variation in the performance of DNA methylation predictors across data preprocessing and normalization strategies. Genome Biol. 2022 10 24; 23(1):225. Ori APS, Lu AT, Horvath S, Ophoff RA. PMID: 36280888; PMCID: PMC9590227.
      View in: PubMed   Mentions: 16     Fields:    Translation:Cells
    155. Small extracellular vesicles from young adipose-derived stem cells prevent frailty, improve health span, and decrease epigenetic age in old mice. Sci Adv. 2022 Oct 21; 8(42):eabq2226. Sanz-Ros J, Romero-García N, Mas-Bargues C, Monleón D, Gordevicius J, Brooke RT, Dromant M, Díaz A, Derevyanko A, Guío-Carrión A, Román-Domínguez A, Inglés M, Blasco MA, Horvath S, Viña J, Borrás C. PMID: 36260670; PMCID: PMC9581480.
      View in: PubMed   Mentions: 64     Fields:    
    156. Mapping brain gene coexpression in daytime transcriptomes unveils diurnal molecular networks and deciphers perturbation gene signatures. Neuron. 2022 10 19; 110(20):3318-3338.e9. Wang N, Langfelder P, Stricos M, Ramanathan L, Richman JB, Vaca R, Plascencia M, Gu X, Zhang S, Tamai TK, Zhang L, Gao F, Ouk K, Lu X, Ivanov LV, Vogt TF, Lu QR, Morton AJ, Colwell CS, Aaronson JS, Rosinski J, Horvath S, Yang XW. PMID: 36265442; PMCID: PMC9665885.
      View in: PubMed   Mentions: 17     Fields:    Translation:AnimalsCells
    157. Immune system disruptions implicated in whole blood epigenome-wide association study of depression among Parkinson's disease patients. Brain Behav Immun Health. 2022 Dec; 26:100530. Paul KC, Kusters C, Furlong M, Zhang K, Yu Y, Folle AD, Del Rosario I, Keener A, Bronstein J, Sinsheimer JS, Horvath S, Ritz B. PMID: 36325427; PMCID: PMC9618774.
      View in: PubMed   Mentions: 6  
    158. Epigenome-Wide Analysis of DNA Methylation and Optimism in Women and Men. Psychosom Med. 2023 01 01; 85(1):89-97. Wang C, DeMeo DL, Kim ES, Cardenas A, Fong KC, Lee LO, Spiro A, Whitsel EA, Horvath S, Hou L, Baccarelli AA, Li Y, Stewart JD, Manson JE, Grodstein F, Kubzansky LD, Schwartz JD. PMID: 36201768; PMCID: PMC9771983.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    159. Rapamycin treatment during development extends life span and health span of male mice and Daphnia magna. Sci Adv. 2022 09 16; 8(37):eabo5482. Shindyapina AV, Cho Y, Kaya A, Tyshkovskiy A, Castro JP, Deik A, Gordevicius J, Poganik JR, Clish CB, Horvath S, Peshkin L, Gladyshev VN. PMID: 36112674; PMCID: PMC9481125.
      View in: PubMed   Mentions: 48     Fields:    Translation:Animals
    160. Author Correction: DNA methylation predicts age and provides insight into exceptional longevity of bats. Nat Commun. 2022 Sep 07; 13(1):5266. Wilkinson GS, Adams DM, Haghani A, Lu AT, Zoller J, Breeze CE, Arnold BD, Ball HC, Carter GG, Cooper LN, Dechmann DKN, Devanna P, Fasel NJ, Galazyuk AV, Günther L, Hurme E, Jones G, Knörnschild M, Lattenkamp EZ, Li CZ, Mayer F, Reinhardt JA, Medellin RA, Nagy M, Pope B, Power ML, Ransome RD, Teeling EC, Vernes SC, Zamora-Mejías D, Zhang J, Faure PA, Greville LJ, Herrera M LG, Flores-Martínez JJ, Horvath S. PMID: 36071115; PMCID: PMC9452676.
      View in: PubMed   Mentions:    Fields:    
    161. Umbilical cord plasma concentrate has beneficial effects on DNA methylation GrimAge and human clinical biomarkers. Aging Cell. 2022 10; 21(10):e13696. Clement J, Yan Q, Agrawal M, Coronado RE, Sturges JA, Horvath M, Lu AT, Brooke RT, Horvath S. PMID: 36052758; PMCID: PMC9577957.
      View in: PubMed   Mentions: 21     Fields:    Translation:HumansCells
    162. Premature aging is associated with higher levels of 8-oxoguanine and increased DNA damage in the Polg mutator mouse. Aging Cell. 2022 09; 21(9):e13669. Yu T, Slone J, Liu W, Barnes R, Opresko PL, Wark L, Mai S, Horvath S, Huang T. PMID: 35993394; PMCID: PMC9470903.
      View in: PubMed   Mentions: 22     Fields:    Translation:Animals
    163. Identification of influential probe types in epigenetic predictions of human traits: implications for microarray design. Clin Epigenetics. 2022 08 10; 14(1):100. Hillary RF, McCartney DL, McRae AF, Campbell A, Walker RM, Hayward C, Horvath S, Porteous DJ, Evans KL, Marioni RE. PMID: 35948928; PMCID: PMC9367152.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    164. LINE-1 RNA causes heterochromatin erosion and is a target for amelioration of senescent phenotypes in progeroid syndromes. Sci Transl Med. 2022 08 10; 14(657):eabl6057. Della Valle F, Reddy P, Yamamoto M, Liu P, Saera-Vila A, Bensaddek D, Zhang H, Prieto Martinez J, Abassi L, Celii M, Ocampo A, Nuñez Delicado E, Mangiavacchi A, Aiese Cigliano R, Rodriguez Esteban C, Horvath S, Izpisua Belmonte JC, Orlando V. PMID: 35947677.
      View in: PubMed   Mentions: 64     Fields:    Translation:HumansAnimalsCells
    165. The relationship between the epigenetic aging biomarker "grimage" and lung function in both the airway and blood of people living with HIV: An observational cohort study. EBioMedicine. 2022 Sep; 83:104206. Hernández Cordero AI, Yang CX, Yang J, Li X, Horvath S, Shaipanich T, MacIsaac J, Lin D, McEwen L, Kobor MS, Guillemi S, Harris M, Lam W, Lam S, Obeidat M, Novak RM, Hudson F, Klinker H, Dharan N, Montaner J, Man SFP, Kunisaki K, Sin DD, Leung JM, INSIGHT START Pulmonary and Genomic Substudy Groups. PMID: 35944348; PMCID: PMC9379521.
      View in: PubMed   Mentions: 10     Fields:    Translation:Humans
    166. Aging the brain: multi-region methylation principal component based clock in the context of Alzheimer's disease. Aging (Albany NY). 2022 07 30; 14(14):5641-5668. Thrush KL, Bennett DA, Gaiteri C, Horvath S, Dyck CHV, Higgins-Chen AT, Levine ME. PMID: 35907208; PMCID: PMC9365556.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansCells
    167. Airway Aging and Methylation Disruptions in HIV-associated Chronic Obstructive Pulmonary Disease. Am J Respir Crit Care Med. 2022 07 15; 206(2):150-160. Hernández Cordero AI, Yang CX, Yang J, Horvath S, Shaipanich T, MacIsaac J, Lin DTS, Kobor MS, Guillemi S, Harris M, Lam W, Lam S, Montaner J, Man SFP, Sin DD, Leung JM. PMID: 35426765; PMCID: PMC9887412.
      View in: PubMed   Mentions: 27     Fields:    Translation:HumansCells
    168. DNA methylation profile in beef cattle is influenced by additive genetics and age. Sci Rep. 2022 07 14; 12(1):12016. Ribeiro AMF, Sanglard LP, Wijesena HR, Ciobanu DC, Horvath S, Spangler ML. PMID: 35835812; PMCID: PMC9283455.
      View in: PubMed   Mentions: 10     Fields:    Translation:AnimalsCells
    169. Analysis of Epigenetic Age Acceleration and Healthy Longevity Among Older US Women. JAMA Netw Open. 2022 07 01; 5(7):e2223285. Jain P, Binder AM, Chen B, Parada H, Gallo LC, Alcaraz J, Horvath S, Bhatti P, Whitsel EA, Jordahl K, Baccarelli AA, Hou L, Stewart JD, Li Y, Justice JN, LaCroix AZ. PMID: 35895062; PMCID: PMC9331104.
      View in: PubMed   Mentions: 37     Fields:    Translation:Humans
    170. Accelerated aging with HIV begins at the time of initial HIV infection. iScience. 2022 Jul 15; 25(7):104488. Breen EC, Sehl ME, Shih R, Langfelder P, Wang R, Horvath S, Bream JH, Duggal P, Martinson J, Wolinsky SM, Martínez-Maza O, Ramirez CM, Jamieson BD. PMID: 35880029; PMCID: PMC9308149.
      View in: PubMed   Mentions: 40  
    171. Alcohol use disorder is associated with DNA methylation-based shortening of telomere length and regulated by TESPA1: implications for aging. Mol Psychiatry. 2022 09; 27(9):3875-3884. Jung J, McCartney DL, Wagner J, Rosoff DB, Schwandt M, Sun H, Wiers CE, de Carvalho LM, Volkow ND, Walker RM, Campbell A, Porteous DJ, McIntosh AM, Marioni RE, Horvath S, Evans KL, Lohoff FW. PMID: 35705636; PMCID: PMC9708583.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansCells
    172. Accelerated epigenetic aging in newborns with Down syndrome. Aging Cell. 2022 07; 21(7):e13652. Xu K, Li S, Muskens IS, Elliott N, Myint SS, Pandey P, Hansen HM, Morimoto LM, Kang AY, Ma X, Metayer C, Mueller BA, Roberts I, Walsh KM, Horvath S, Wiemels JL, Wiemels JL, de Smith AJ. PMID: 35661546; PMCID: PMC9282838.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansCells
    173. Association of Epigenetic Age Acceleration With Incident Mild Cognitive Impairment and Dementia Among Older Women. J Gerontol A Biol Sci Med Sci. 2022 06 01; 77(6):1239-1244. Shadyab AH, McEvoy LK, Horvath S, Whitsel EA, Rapp SR, Espeland MA, Resnick SM, Manson JE, Chen JC, Chen BH, Li W, Hayden KM, Bao W, Kusters CDJ, LaCroix AZ. PMID: 34417803; PMCID: PMC9159659.
      View in: PubMed   Mentions: 18     Fields:    Translation:Humans
    174. Telomere length and epigenetic clocks as markers of cellular aging: a comparative study. Geroscience. 2022 06; 44(3):1861-1869. Pearce EE, Alsaggaf R, Katta S, Dagnall C, Aubert G, Hicks BD, Spellman SR, Savage SA, Horvath S, Gadalla SM. PMID: 35585300; PMCID: PMC9213578.
      View in: PubMed   Mentions: 36     Fields:    Translation:HumansCells
    175. DNA methylation clocks for dogs and humans. Proc Natl Acad Sci U S A. 2022 05 24; 119(21):e2120887119. Horvath S, Lu AT, Haghani A, Zoller JA, Li CZ, Lim AR, Brooke RT, Raj K, Serres-Armero A, Dreger DL, Hogan AN, Plassais J, Ostrander EA. PMID: 35580182; PMCID: PMC9173771.
      View in: PubMed   Mentions: 42     Fields:    Translation:HumansAnimalsCells
    176. The relationship between epigenetic age and the hallmarks of aging in human cells. Nat Aging. 2022 06; 2(6):484-493. Kabacik S, Lowe D, Fransen L, Leonard M, Ang SL, Whiteman C, Corsi S, Cohen H, Felton S, Bali R, Horvath S, Raj K. PMID: 37034474; PMCID: PMC10077971.
      View in: PubMed   Mentions: 109     Fields:    Translation:HumansCells
    177. Making sense of the ageing methylome. Nat Rev Genet. 2022 10; 23(10):585-605. Seale K, Horvath S, Teschendorff A, Eynon N, Voisin S. PMID: 35501397.
      View in: PubMed   Mentions: 131     Fields:    Translation:HumansCells
    178. Epigenetic clock and methylation studies in marsupials: opossums, Tasmanian devils, kangaroos, and wallabies. Geroscience. 2022 06; 44(3):1825-1845. Horvath S, Haghani A, Zoller JA, Raj K, Sinha I, Robeck TR, Black P, Couzens A, Lau C, Manoyan M, Ruiz YA, Talbott A, Belov K, Hogg CJ, Sears KE. PMID: 35449380; PMCID: PMC9213610.
      View in: PubMed   Mentions: 10     Fields:    Translation:AnimalsCells
    179. The impact of reproductive factors on DNA methylation-based telomere length in healthy breast tissue. NPJ Breast Cancer. 2022 Apr 13; 8(1):48. Sehl ME, Henry JE, Storniolo AM, Horvath S, Ganz PA. PMID: 35418123; PMCID: PMC9007943.
      View in: PubMed   Mentions: 3  
    180. HIV, pathology and epigenetic age acceleration in different human tissues. Geroscience. 2022 06; 44(3):1609-1620. Horvath S, Lin DTS, Kobor MS, Zoller JA, Said JW, Morgello S, Singer E, Yong WH, Jamieson BD, Levine AJ. PMID: 35411474; PMCID: PMC9213580.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansCells
    181. Genetic loci and metabolic states associated with murine epigenetic aging. Elife. 2022 04 07; 11. Mozhui K, Lu AT, Li CZ, Haghani A, Sandoval-Sierra JV, Wu Y, Williams RW, Horvath S. PMID: 35389339; PMCID: PMC9049972.
      View in: PubMed   Mentions: 32     Fields:    Translation:AnimalsCells
    182. Assessing the causal role of epigenetic clocks in the development of multiple cancers: a Mendelian randomization study. Elife. 2022 03 29; 11. Morales Berstein F, McCartney DL, Lu AT, Tsilidis KK, Bouras E, Haycock P, Burrows K, Phipps AI, Buchanan DD, Cheng I, PRACTICAL consortium, Martin RM, Davey Smith G, Relton CL, Horvath S, Marioni RE, Richardson TG, Richmond RC. PMID: 35346416; PMCID: PMC9049976.
      View in: PubMed   Mentions: 46     Fields:    Translation:Humans
    183. Association of subjective social status with epigenetic aging among Black and White women. Psychoneuroendocrinology. 2022 07; 141:105748. Hamlat EJ, Adler NE, Laraia B, Surachman A, Lu AT, Zhang J, Horvath S, Epel ES. PMID: 35397259; PMCID: PMC10228718.
      View in: PubMed   Mentions: 14     Fields:    Translation:Humans
    184. Hibernation slows epigenetic ageing in yellow-bellied marmots. Nat Ecol Evol. 2022 04; 6(4):418-426. Pinho GM, Martin JGA, Farrell C, Haghani A, Zoller JA, Zhang J, Snir S, Pellegrini M, Wayne RK, Blumstein DT, Horvath S. PMID: 35256811; PMCID: PMC8986532.
      View in: PubMed   Mentions: 32     Fields:    Translation:Animals
    185. In vivo partial reprogramming alters age-associated molecular changes during physiological aging in mice. Nat Aging. 2022 03; 2(3):243-253. Browder KC, Reddy P, Yamamoto M, Haghani A, Guillen IG, Sahu S, Wang C, Luque Y, Prieto J, Shi L, Shojima K, Hishida T, Lai Z, Li Q, Choudhury FK, Wong WR, Liang Y, Sangaraju D, Sandoval W, Esteban CR, Delicado EN, Garcia PG, Pawlak M, Vander Heiden JA, Horvath S, Jasper H, Izpisua Belmonte JC. PMID: 37118377.
      View in: PubMed   Mentions: 115     Fields:    Translation:Animals
    186. Erratum to "Increased Menopausal Age Reduces the Risk of Parkinson's Disease: A Mendelian Approach". Mov Disord. 2022 06; 37(6):1282-1283. Kusters CDJ, Paul KC, Duarte Folle A, Keener AM, Bronstein JM, Bertram L, Hansen J, Horvath S, Sinsheimer JS, Lill CM, Ritz BR. PMID: 35245402; PMCID: PMC10566527.
      View in: PubMed   Mentions:    Fields:    
    187. Increased Rate of Epigenetic Aging in Men Living With HIV Prior to Treatment. Front Genet. 2021; 12:796547. Sehl ME, Breen EC, Shih R, Chen L, Wang R, Horvath S, Bream JH, Duggal P, Martinson J, Wolinsky SM, Martinez-Maza O, Ramirez CM, Jamieson BD. PMID: 35295196; PMCID: PMC8919029.
      View in: PubMed   Mentions: 16  
    188. A mammalian methylation array for profiling methylation levels at conserved sequences. Nat Commun. 2022 02 10; 13(1):783. Arneson A, Haghani A, Thompson MJ, Pellegrini M, Kwon SB, Vu H, Maciejewski E, Yao M, Li CZ, Lu AT, Morselli M, Rubbi L, Barnes B, Hansen KD, Zhou W, Breeze CE, Ernst J, Horvath S. PMID: 35145108; PMCID: PMC8831611.
      View in: PubMed   Mentions: 122     Fields:    Translation:HumansAnimalsCells
    189. Uninterrupted CAG repeat drives striatum-selective transcriptionopathy and nuclear pathogenesis in human Huntingtin BAC mice. Neuron. 2022 04 06; 110(7):1173-1192.e7. Gu X, Richman J, Langfelder P, Wang N, Zhang S, Bañez-Coronel M, Wang HB, Yang L, Ramanathan L, Deng L, Park CS, Choi CR, Cantle JP, Gao F, Gray M, Coppola G, Bates GP, Ranum LPW, Horvath S, Colwell CS, Yang XW. PMID: 35114102; PMCID: PMC9462388.
      View in: PubMed   Mentions: 38     Fields:    Translation:HumansAnimalsCells
    190. Plasma lipid profiles in early adulthood are associated with epigenetic aging in the Coronary Artery Risk Development in Young Adults (CARDIA) Study. Clin Epigenetics. 2022 01 31; 14(1):16. Gao T, Wilkins JT, Zheng Y, Joyce BT, Jacobs DR, Schreiner PJ, Horvath S, Greenland P, Lloyd-Jones D, Hou L. PMID: 35101102; PMCID: PMC8805309.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansCells
    191. DNA methylation signatures in Blood DNA of Hutchinson-Gilford Progeria syndrome. Aging Cell. 2022 02; 21(2):e13555. Bejaoui Y, Razzaq A, Yousri NA, Oshima J, Megarbane A, Qannan A, Potabattula R, Alam T, Martin GM, Horn HF, Haaf T, Horvath S, El Hajj N. PMID: 35045206; PMCID: PMC8844112.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansCells
    192. Epigenetic aging of the demographically non-aging naked mole-rat. Nat Commun. 2022 01 17; 13(1):355. Kerepesi C, Meer MV, Ablaeva J, Amoroso VG, Lee SG, Zhang B, Gerashchenko MV, Trapp A, Yim SH, Lu AT, Levine ME, Seluanov A, Horvath S, Park TJ, Gorbunova V, Gladyshev VN. PMID: 35039495; PMCID: PMC8763950.
      View in: PubMed   Mentions: 22     Fields:    Translation:HumansAnimalsCells
    193. Higher diet quality relates to decelerated epigenetic aging. Am J Clin Nutr. 2022 01 11; 115(1):163-170. Kim Y, Huan T, Joehanes R, McKeown NM, Horvath S, Levy D, Ma J. PMID: 34134146; PMCID: PMC8755029.
      View in: PubMed   Mentions: 67     Fields:    Translation:HumansCells
    194. DNA methylation aging and transcriptomic studies in horses. Nat Commun. 2022 01 10; 13(1):40. Horvath S, Haghani A, Peng S, Hales EN, Zoller JA, Raj K, Larison B, Robeck TR, Petersen JL, Bellone RR, Finno CJ. PMID: 35013267; PMCID: PMC8748428.
      View in: PubMed   Mentions: 29     Fields:    Translation:HumansAnimalsCells
    195. Stochastic Epigenetic Mutations Influence Parkinson's Disease Risk, Progression, and Mortality. J Parkinsons Dis. 2022; 12(2):545-556. Chen GK, Yan Q, Paul KC, Kusters CDJ, Folle AD, Furlong M, Keener A, Bronstein J, Horvath S, Ritz B. PMID: 34842194; PMCID: PMC9076404.
      View in: PubMed   Mentions: 11     Fields:    Translation:Humans
    196. Development of Epigenetic Clocks for Key Ruminant Species. Genes (Basel). 2021 12 30; 13(1). Caulton A, Dodds KG, McRae KM, Couldrey C, Horvath S, Clarke SM. PMID: 35052436; PMCID: PMC8775075.
      View in: PubMed   Mentions: 19     Fields:    Translation:AnimalsCells
    197. DNA methylation clocks tick in naked mole rats but queens age more slowly than nonbreeders. Nat Aging. 2022 01; 2(1):46-59. Horvath S, Haghani A, Macoretta N, Ablaeva J, Zoller JA, Li CZ, Zhang J, Takasugi M, Zhao Y, Rydkina E, Zhang Z, Emmrich S, Raj K, Seluanov A, Faulkes CG, Gorbunova V. PMID: 35368774; PMCID: PMC8975251.
      View in: PubMed   Mentions: 48     Fields:    Translation:HumansAnimalsCells
    198. Associations between DNA methylation and BMI vary by metabolic health status: a potential link to disparate cardiovascular outcomes. Clin Epigenetics. 2021 12 22; 13(1):230. Do WL, Nguyen S, Yao J, Guo X, Whitsel EA, Demerath E, Rotter JI, Rich SS, Lange L, Ding J, Van Den Berg D, Liu Y, Justice AE, Guan W, Horvath S, Assimes TL, Bhatti P, Jordahl K, Shadyab A, Valencia CI, Stein AD, Smith A, Staimez LR, Conneely K, Narayan KMV. PMID: 34937574; PMCID: PMC8697469.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansCells
    199. Epigenetic models developed for plains zebras predict age in domestic horses and endangered equids. Commun Biol. 2021 12 17; 4(1):1412. Larison B, Pinho GM, Haghani A, Zoller JA, Li CZ, Finno CJ, Farrell C, Kaelin CB, Barsh GS, Wooding B, Robeck TR, Maddox D, Pellegrini M, Horvath S. PMID: 34921240; PMCID: PMC8683477.
      View in: PubMed   Mentions: 17  Translation:Animals
    200. Epigenome-wide association study of serum urate reveals insights into urate co-regulation and the SLC2A9 locus. Nat Commun. 2021 12 09; 12(1):7173. Tin A, Schlosser P, Matias-Garcia PR, Thio CHL, Joehanes R, Liu H, Yu Z, Weihs A, Hoppmann A, Grundner-Culemann F, Min JL, Kuhns VLH, Adeyemo AA, Agyemang C, Ärnlöv J, Aziz NA, Baccarelli A, Bochud M, Brenner H, Bressler J, Breteler MMB, Carmeli C, Chaker L, Coresh J, Corre T, Correa A, Cox SR, Delgado GE, Eckardt KU, Ekici AB, Endlich K, Floyd JS, Fraszczyk E, Gao X, Gào X, Gelber AC, Ghanbari M, Ghasemi S, Gieger C, Greenland P, Grove ML, Harris SE, Hemani G, Henneman P, Herder C, Horvath S, Hou L, Hurme MA, Hwang SJ, Kardia SLR, Kasela S, Kleber ME, Koenig W, Kooner JS, Kronenberg F, Kühnel B, Ladd-Acosta C, Lehtimäki T, Lind L, Liu D, Lloyd-Jones DM, Lorkowski S, Lu AT, Marioni RE, März W, McCartney DL, Meeks KAC, Milani L, Mishra PP, Nauck M, Nowak C, Peters A, Prokisch H, Psaty BM, Raitakari OT, Ratliff SM, Reiner AP, Schöttker B, Schwartz J, Sedaghat S, Smith JA, Sotoodehnia N, Stocker HR, Stringhini S, Sundström J, Swenson BR, van Meurs JBJ, van Vliet-Ostaptchouk JV, Venema A, Völker U, Winkelmann J, Wolffenbuttel BHR, Zhao W, Zheng Y, Estonian Biobank Research Team, Genetics of DNA Methylation Consortium, Loh M, Snieder H, Waldenberger M, Levy D, Akilesh S, Woodward OM, Susztak K, Teumer A, Köttgen A. PMID: 34887389; PMCID: PMC8660809.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansCells
    201. Meta-analyses identify DNA methylation associated with kidney function and damage. Nat Commun. 2021 12 09; 12(1):7174. Schlosser P, Tin A, Matias-Garcia PR, Thio CHL, Joehanes R, Liu H, Weihs A, Yu Z, Hoppmann A, Grundner-Culemann F, Min JL, Adeyemo AA, Agyemang C, Ärnlöv J, Aziz NA, Baccarelli A, Bochud M, Brenner H, Breteler MMB, Carmeli C, Chaker L, Chambers JC, Cole SA, Coresh J, Corre T, Correa A, Cox SR, de Klein N, Delgado GE, Domingo-Relloso A, Eckardt KU, Ekici AB, Endlich K, Evans KL, Floyd JS, Fornage M, Franke L, Fraszczyk E, Gao X, Gào X, Ghanbari M, Ghasemi S, Gieger C, Greenland P, Grove ML, Harris SE, Hemani G, Henneman P, Herder C, Horvath S, Hou L, Hurme MA, Hwang SJ, Jarvelin MR, Kardia SLR, Kasela S, Kleber ME, Koenig W, Kooner JS, Kramer H, Kronenberg F, Kühnel B, Lehtimäki T, Lind L, Liu D, Liu Y, Lloyd-Jones DM, Lohman K, Lorkowski S, Lu AT, Marioni RE, März W, McCartney DL, Meeks KAC, Milani L, Mishra PP, Nauck M, Navas-Acien A, Nowak C, Peters A, Prokisch H, Psaty BM, Raitakari OT, Ratliff SM, Reiner AP, Rosas SE, Schöttker B, Schwartz J, Sedaghat S, Smith JA, Sotoodehnia N, Stocker HR, Stringhini S, Sundström J, Swenson BR, Tellez-Plaza M, van Meurs JBJ, van Vliet-Ostaptchouk JV, Venema A, Verweij N, Walker RM, Wielscher M, Winkelmann J, Wolffenbuttel BHR, Zhao W, Zheng Y, Estonian Biobank Research Team, Genetics of DNA Methylation Consortium, Loh M, Snieder H, Levy D, Waldenberger M, Susztak K, Köttgen A, Teumer A. PMID: 34887417; PMCID: PMC8660832.
      View in: PubMed   Mentions: 46     Fields:    Translation:HumansCells
    202. DNA methylation-based surrogates of plasma proteins are associated with Parkinson's disease risk. J Neurol Sci. 2021 Dec 15; 431:120046. Fu KA, Paul KC, Lu AT, Horvath S, Keener AM, Bordelon Y, Bronstein JM, Ritz B. PMID: 34768133; PMCID: PMC8769489.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCells
    203. DNA methylation as a tool to explore ageing in wild roe deer populations. Mol Ecol Resour. 2022 Apr; 22(3):1002-1015. Lemaître JF, Rey B, Gaillard JM, Régis C, Gilot-Fromont E, Débias F, Duhayer J, Pardonnet S, Pellerin M, Haghani A, Zoller JA, Li CZ, Horvath S. PMID: 34665921; PMCID: PMC9297961.
      View in: PubMed   Mentions: 14     Fields:    Translation:AnimalsCells
    204. An Analysis of Methylome Evolution in Primates. Mol Biol Evol. 2021 10 27; 38(11):4700-4714. Sahm A, Koch P, Horvath S, Hoffmann S. PMID: 34175932; PMCID: PMC8557466.
      View in: PubMed   Mentions: 4     Fields:    Translation:AnimalsCells
    205. Methylation studies in Peromyscus: aging, altitude adaptation, and monogamy. Geroscience. 2022 02; 44(1):447-461. Horvath S, Haghani A, Zoller JA, Naderi A, Soltanmohammadi E, Farmaki E, Kaza V, Chatzistamou I, Kiaris H. PMID: 34698996; PMCID: PMC8810952.
      View in: PubMed   Mentions: 7     Fields:    Translation:AnimalsCells
    206. Host methylation predicts SARS-CoV-2 infection and clinical outcome. Commun Med (Lond). 2021; 1(1):42. Konigsberg IR, Barnes B, Campbell M, Davidson E, Zhen Y, Pallisard O, Boorgula MP, Cox C, Nandy D, Seal S, Crooks K, Sticca E, Harrison GF, Hopkinson A, Vest A, Arnold CG, Kahn MG, Kao DP, Peterson BR, Wicks SJ, Ghosh D, Horvath S, Zhou W, Mathias RA, Norman PJ, Porecha R, Yang IV, Gignoux CR, Monte AA, Taye A, Barnes KC. PMID: 35072167; PMCID: PMC8767772.
      View in: PubMed   Mentions: 40  
    207. Epigenetic clock and methylation studies in vervet monkeys. Geroscience. 2022 04; 44(2):699-717. Jasinska AJ, Haghani A, Zoller JA, Li CZ, Arneson A, Ernst J, Kavanagh K, Jorgensen MJ, Mattison JA, Wojta K, Choi OW, DeYoung J, Li X, Rao AW, Coppola G, Freimer NB, Woods RP, Horvath S. PMID: 34591235; PMCID: PMC9135907.
      View in: PubMed   Mentions: 16     Fields:    Translation:AnimalsCells
    208. Epigenetic Age and the Risk of Incident Atrial Fibrillation. Circulation. 2021 12 14; 144(24):1899-1911. Roberts JD, Vittinghoff E, Lu AT, Alonso A, Wang B, Sitlani CM, Mohammadi-Shemirani P, Fornage M, Kornej J, Brody JA, Arking DE, Lin H, Heckbert SR, Prokic I, Ghanbari M, Skanes AC, Bartz TM, Perez MV, Taylor KD, Lubitz SA, Ellinor PT, Lunetta KL, Pankow JS, Paré G, Sotoodehnia N, Benjamin EJ, Horvath S, Marcus GM. PMID: 34587750; PMCID: PMC8671333.
      View in: PubMed   Mentions: 71     Fields:    Translation:HumansCellsCTClinical Trials
    209. Accelerated hematopoietic mitotic aging measured by DNA methylation, blood cell lineage, and Parkinson's disease. BMC Genomics. 2021 Sep 26; 22(1):696. Paul KC, Binder AM, Horvath S, Kusters C, Yan Q, Rosario ID, Yu Y, Bronstein J, Ritz B. PMID: 34565328; PMCID: PMC8474781.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansCells
    210. Transposon-triggered innate immune response confers cancer resistance to the blind mole rat. Nat Immunol. 2021 10; 22(10):1219-1230. Zhao Y, Oreskovic E, Zhang Q, Lu Q, Gilman A, Lin YS, He J, Zheng Z, Lu JY, Lee J, Ke Z, Ablaeva J, Sweet MJ, Horvath S, Zhang Z, Nevo E, Seluanov A, Gorbunova V. PMID: 34556881; PMCID: PMC8488014.
      View in: PubMed   Mentions: 47     Fields:    Translation:HumansAnimalsCells
    211. Epigenetic clock and DNA methylation analysis of porcine models of aging and obesity. Geroscience. 2021 10; 43(5):2467-2483. Schachtschneider KM, Schook LB, Meudt JJ, Shanmuganayagam D, Zoller JA, Haghani A, Li CZ, Zhang J, Yang A, Raj K, Horvath S. PMID: 34523051; PMCID: PMC8599541.
      View in: PubMed   Mentions: 25     Fields:    Translation:AnimalsCells
    212. Epigenetic clock and methylation studies in the rhesus macaque. Geroscience. 2021 10; 43(5):2441-2453. Horvath S, Zoller JA, Haghani A, Jasinska AJ, Raj K, Breeze CE, Ernst J, Vaughan KL, Mattison JA. PMID: 34487267; PMCID: PMC8599607.
      View in: PubMed   Mentions: 32     Fields:    Translation:AnimalsCells
    213. DNA methylation age analysis of rapamycin in common marmosets. Geroscience. 2021 10; 43(5):2413-2425. Horvath S, Zoller JA, Haghani A, Lu AT, Raj K, Jasinska AJ, Mattison JA, Salmon AB. PMID: 34482522; PMCID: PMC8599537.
      View in: PubMed   Mentions: 28     Fields:    Translation:AnimalsCells
    214. Epigenetic clock and methylation studies in cats. Geroscience. 2021 10; 43(5):2363-2378. Raj K, Szladovits B, Haghani A, Zoller JA, Li CZ, Black P, Maddox D, Robeck TR, Horvath S. PMID: 34463900; PMCID: PMC8599556.
      View in: PubMed   Mentions: 26     Fields:    Translation:AnimalsCells
    215. Epigenetic Age Acceleration Reflects Long-Term Cardiovascular Health. Circ Res. 2021 10; 129(8):770-781. Joyce BT, Gao T, Zheng Y, Ma J, Hwang SJ, Liu L, Nannini D, Horvath S, Lu AT, Bai Allen N, Jacobs DR, Gross M, Krefman A, Ning H, Liu K, Lewis CE, Schreiner PJ, Sidney S, Shikany JM, Levy D, Greenland P, Hou L, Lloyd-Jones D. PMID: 34428927; PMCID: PMC8484046.
      View in: PubMed   Mentions: 83     Fields:    Translation:HumansCellsCTClinical Trials
    216. Increased Menopausal Age Reduces the Risk of Parkinson's Disease: A Mendelian Randomization Approach. Mov Disord. 2021 10; 36(10):2264-2272. Kusters CDJ, Paul KC, Duarte Folle A, Keener AM, Bronstein JM, Bertram L, Hansen J, Horvath S, Sinsheimer JS, Lill CM, Ritz BR. PMID: 34426982; PMCID: PMC8530889.
      View in: PubMed   Mentions: 27     Fields:    Translation:Humans
    217. Castration delays epigenetic aging and feminizes DNA methylation at androgen-regulated loci. Elife. 2021 07 06; 10. Sugrue VJ, Zoller JA, Narayan P, Lu AT, Ortega-Recalde OJ, Grant MJ, Bawden CS, Rudiger SR, Haghani A, Bond DM, Hore RR, Garratt M, Sears KE, Wang N, Yang XW, Snell RG, Hore TA, Horvath S. PMID: 34227937; PMCID: PMC8260231.
      View in: PubMed   Mentions: 37     Fields:    Translation:AnimalsCells
    218. Publisher Correction: A multi-ethnic epigenome-wide association study of leukocyte DNA methylation and blood lipids. Nat Commun. 2021 Jul 06; 12(1):4256. Jhun MA, Mendelson M, Wilson R, Gondalia R, Joehanes R, Salfati E, Zhao X, Braun KVE, Do AN, Hedman ÅK, Zhang T, Carnero-Montoro E, Shen J, Bartz TM, Brody JA, Montasser ME, O'Connell JR, Yao C, Xia R, Boerwinkle E, Grove M, Guan W, Liliane P, Singmann P, Müller-Nurasyid M, Meitinger T, Gieger C, Peters A, Zhao W, Ware EB, Smith JA, Dhana K, van Meurs J, Uitterlinden A, Ikram MA, Ghanbari M, Zhi D, Gustafsson S, Lind L, Li S, Sun D, Spector TD, Chen YI, Damcott C, Shuldiner AR, Absher DM, Horvath S, Tsao PS, Kardia S, Psaty BM, Sotoodehnia N, Bell JT, Ingelsson E, Chen W, Dehghan A, Arnett DK, Waldenberger M, Hou L, Whitsel EA, Baccarelli A, Levy D, Fornage M, Irvin MR, Assimes TL. PMID: 34230475; PMCID: PMC8260765.
      View in: PubMed   Mentions:    Fields:    
    219. Meta-analysis of genome-wide DNA methylation and integrative omics of age in human skeletal muscle. J Cachexia Sarcopenia Muscle. 2021 08; 12(4):1064-1078. Voisin S, Jacques M, Landen S, Harvey NR, Haupt LM, Griffiths LR, Gancheva S, Ouni M, Jähnert M, Ashton KJ, Coffey VG, Thompson JM, Doering TM, Gabory A, Junien C, Caiazzo R, Verkindt H, Raverdy V, Pattou F, Froguel P, Craig JM, Blocquiaux S, Thomis M, Sharples AP, Schürmann A, Roden M, Horvath S, Eynon N. PMID: 34196129; PMCID: PMC8350206.
      View in: PubMed   Mentions: 44     Fields:    Translation:HumansCells
    220. Genome-wide association studies identify 137 genetic loci for DNA methylation biomarkers of aging. Genome Biol. 2021 06 29; 22(1):194. McCartney DL, Min JL, Richmond RC, Lu AT, Sobczyk MK, Davies G, Broer L, Guo X, Jeong A, Jung J, Kasela S, Katrinli S, Kuo PL, Matias-Garcia PR, Mishra PP, Nygaard M, Palviainen T, Patki A, Raffield LM, Ratliff SM, Richardson TG, Robinson O, Soerensen M, Sun D, Tsai PC, van der Zee MD, Walker RM, Wang X, Wang Y, Xia R, Xu Z, Yao J, Zhao W, Correa A, Boerwinkle E, Dugué PA, Durda P, Elliott HR, Gieger C, Genetics of DNA Methylation Consortium, de Geus EJC, Harris SE, Hemani G, Imboden M, Kähönen M, Kardia SLR, Kresovich JK, Li S, Lunetta KL, Mangino M, Mason D, McIntosh AM, Mengel-From J, Moore AZ, Murabito JM, NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium, Ollikainen M, Pankow JS, Pedersen NL, Peters A, Polidoro S, Porteous DJ, Raitakari O, Rich SS, Sandler DP, Sillanpää E, Smith AK, Southey MC, Strauch K, Tiwari H, Tanaka T, Tillin T, Uitterlinden AG, Van Den Berg DJ, van Dongen J, Wilson JG, Wright J, Yet I, Arnett D, Bandinelli S, Bell JT, Binder AM, Boomsma DI, Chen W, Christensen K, Conneely KN, Elliott P, Ferrucci L, Fornage M, Hägg S, Hayward C, Irvin M, Kaprio J, Lawlor DA, Lehtimäki T, Lohoff FW, Milani L, Milne RL, Probst-Hensch N, Reiner AP, Ritz B, Rotter JI, Smith JA, Taylor JA, van Meurs JBJ, Vineis P, Waldenberger M, Deary IJ, Relton CL, Horvath S, Marioni RE. PMID: 34187551; PMCID: PMC8243879.
      View in: PubMed   Mentions: 171     Fields:    Translation:HumansCells
    221. A multi-ethnic epigenome-wide association study of leukocyte DNA methylation and blood lipids. Nat Commun. 2021 06 28; 12(1):3987. Jhun MA, Mendelson M, Wilson R, Gondalia R, Joehanes R, Salfati E, Zhao X, Braun KVE, Do AN, Hedman ÅK, Zhang T, Carnero-Montoro E, Shen J, Bartz TM, Brody JA, Montasser ME, O'Connell JR, Yao C, Xia R, Boerwinkle E, Grove M, Guan W, Liliane P, Singmann P, Müller-Nurasyid M, Meitinger T, Gieger C, Peters A, Zhao W, Ware EB, Smith JA, Dhana K, van Meurs J, Uitterlinden A, Ikram MA, Ghanbari M, Zhi D, Gustafsson S, Lind L, Li S, Sun D, Spector TD, Chen YI, Damcott C, Shuldiner AR, Absher DM, Horvath S, Tsao PS, Kardia S, Psaty BM, Sotoodehnia N, Bell JT, Ingelsson E, Chen W, Dehghan A, Arnett DK, Waldenberger M, Hou L, Whitsel EA, Baccarelli A, Levy D, Fornage M, Irvin MR, Assimes TL. PMID: 34183656; PMCID: PMC8238961.
      View in: PubMed   Mentions: 24     Fields:    Translation:HumansCells
    222. Epigenetic clock and methylation studies in elephants. Aging Cell. 2021 07; 20(7):e13414. Prado NA, Brown JL, Zoller JA, Haghani A, Yao M, Bagryanova LR, Campana MG, E Maldonado J, Raj K, Schmitt D, Robeck TR, Horvath S. PMID: 34118182; PMCID: PMC8282242.
      View in: PubMed   Mentions: 34     Fields:    Translation:AnimalsCells
    223. DNA-methylation-based telomere length estimator: comparisons with measurements from flow FISH and qPCR. Aging (Albany NY). 2021 06 03; 13(11):14675-14686. Pearce EE, Horvath S, Katta S, Dagnall C, Aubert G, Hicks BD, Spellman SR, Katki H, Savage SA, Alsaggaf R, Gadalla SM. PMID: 34083495; PMCID: PMC8221337.
      View in: PubMed   Mentions: 24     Fields:    Translation:HumansCells
    224. DNAm-based signatures of accelerated aging and mortality in blood are associated with low renal function. Clin Epigenetics. 2021 06 02; 13(1):121. Matías-García PR, Ward-Caviness CK, Raffield LM, Gao X, Zhang Y, Wilson R, Gào X, Nano J, Bostom A, Colicino E, Correa A, Coull B, Eaton C, Hou L, Just AC, Kunze S, Lange L, Lange E, Lin X, Liu S, Nwanaji-Enwerem JC, Reiner A, Shen J, Schöttker B, Vokonas P, Zheng Y, Young B, Schwartz J, Horvath S, Lu A, Whitsel EA, Koenig W, Adamski J, Winkelmann J, Brenner H, Baccarelli AA, Gieger C, Peters A, Franceschini N, Waldenberger M. PMID: 34078457; PMCID: PMC8170969.
      View in: PubMed   Mentions: 25     Fields:    Translation:HumansCells
    225. Multi-species and multi-tissue methylation clocks for age estimation in toothed whales and dolphins. Commun Biol. 2021 05 31; 4(1):642. Robeck TR, Fei Z, Lu AT, Haghani A, Jourdain E, Zoller JA, Li CZ, Steinman KJ, DiRocco S, Schmitt T, Osborn S, Van Bonn B, Katsumata E, Mergl J, Almunia J, Rodriguez M, Haulena M, Dold C, Horvath S. PMID: 34059764; PMCID: PMC8167141.
      View in: PubMed   Mentions: 30  Translation:AnimalsCells
    226. Clonal hematopoiesis associated with epigenetic aging and clinical outcomes. Aging Cell. 2021 06; 20(6):e13366. Nachun D, Lu AT, Bick AG, Natarajan P, Weinstock J, Szeto MD, Kathiresan S, Abecasis G, Taylor KD, Guo X, Tracy R, Durda P, Liu Y, Johnson C, Rich SS, Van Den Berg D, Laurie C, Blackwell T, Papanicolaou GJ, Correa A, Raffield LM, Johnson AD, Murabito J, Manson JE, Desai P, Kooperberg C, Assimes TL, Levy D, Rotter JI, Reiner AP, Whitsel EA, Wilson JG, Horvath S, Jaiswal S, NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium. PMID: 34050697; PMCID: PMC8208788.
      View in: PubMed   Mentions: 85     Fields:    Translation:Humans
    227. Occurrence of Accelerated Epigenetic Aging and Methylation Disruptions in Human Immunodeficiency Virus Infection Before Antiretroviral Therapy. J Infect Dis. 2021 05 28; 223(10):1681-1689. Yang CX, Schon E, Obeidat M, Kobor MS, McEwen L, MacIsaac J, Lin D, Novak RM, Hudson F, Klinker H, Dharan N, Horvath S, Bourbeau J, Tan W, Sin DD, Man SFP, Kunisaki K, Leung JM. PMID: 32959881; PMCID: PMC8161637.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansCells
    228. Epigenome-wide association study of diet quality in the Women's Health Initiative and TwinsUK cohort. Int J Epidemiol. 2021 05 17; 50(2):675-684. Do WL, Whitsel EA, Costeira R, Masachs OM, Le Roy CI, Bell JT, Staimez LR, Stein AD, Smith AK, Horvath S, Assimes TL, Liu S, Manson JE, Shadyab AH, Li Y, Hou L, Bhatti P, Jordahl K, Narayan KMV, Conneely KN. PMID: 33354722; PMCID: PMC8128469.
      View in: PubMed   Mentions: 21     Fields:    Translation:HumansCells
    229. Author Correction: DNA methylation predicts age and provides insight into exceptional longevity of bats. Nat Commun. 2021 May 05; 12(1):2652. Wilkinson GS, Adams DM, Haghani A, Lu AT, Zoller J, Breeze CE, Arnold BD, Ball HC, Carter GG, Cooper LN, Dechmann DKN, Devanna P, Fasel NJ, Galazyuk AV, Günther L, Hurme E, Jones G, Knörnschild M, Lattenkamp EZ, Li CZ, Mayer F, Reinhardt JA, Medellin RA, Nagy M, Pope B, Power ML, Ransome RD, Teeling EC, Vernes SC, Zamora-Mejías D, Zhang J, Faure PA, Greville LJ, Horvath S, Herrera M LG, Flores-Martínez JJ. PMID: 33953189; PMCID: PMC8100179.
      View in: PubMed   Mentions: 1     Fields:    
    230. GrimAge Outperforms Other Epigenetic Clocks in the Prediction of Age-Related Clinical Phenotypes and All-Cause Mortality. J Gerontol A Biol Sci Med Sci. 2021 04 30; 76(5):741-749. McCrory C, Fiorito G, Hernandez B, Polidoro S, O'Halloran AM, Hever A, Ni Cheallaigh C, Lu AT, Horvath S, Vineis P, Kenny RA. PMID: 33211845; PMCID: PMC8087266.
      View in: PubMed   Mentions: 237     Fields:    Translation:HumansCells
    231. Epigenome-wide association study of kidney function identifies trans-ethnic and ethnic-specific loci. Genome Med. 2021 04 30; 13(1):74. Breeze CE, Batorsky A, Lee MK, Szeto MD, Xu X, McCartney DL, Jiang R, Patki A, Kramer HJ, Eales JM, Raffield L, Lange L, Lange E, Durda P, Liu Y, Tracy RP, Van Den Berg D, NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium, TOPMed MESA Multi-Omics Working Group, Evans KL, Kraus WE, Shah S, Tiwari HK, Hou L, Whitsel EA, Jiang X, Charchar FJ, Baccarelli AA, Rich SS, Morris AP, Irvin MR, Arnett DK, Hauser ER, Rotter JI, Correa A, Hayward C, Horvath S, Marioni RE, Tomaszewski M, Beck S, Berndt SI, London SJ, Mychaleckyj JC, Franceschini N. PMID: 33931109; PMCID: PMC8088054.
      View in: PubMed   Mentions: 29     Fields:    Translation:HumansCells
    232. Age-dependent instability of mature neuronal fate in induced neurons from Alzheimer's patients. Cell Stem Cell. 2021 09 02; 28(9):1533-1548.e6. Mertens J, Herdy JR, Traxler L, Schafer ST, Schlachetzki JCM, Böhnke L, Reid DA, Lee H, Zangwill D, Fernandes DP, Agarwal RK, Lucciola R, Zhou-Yang L, Karbacher L, Edenhofer F, Stern S, Horvath S, Paquola ACM, Glass CK, Yuan SH, Ku M, Szücs A, Goldstein LSB, Galasko D, Gage FH. PMID: 33910058; PMCID: PMC8423435.
      View in: PubMed   Mentions: 133     Fields:    Translation:HumansCells
    233. Postpartum sleep loss and accelerated epigenetic aging. Sleep Health. 2021 06; 7(3):362-367. Carroll JE, Ross KM, Horvath S, Okun M, Hobel C, Rentscher KE, Coussons-Read M, Schetter CD. PMID: 33903077; PMCID: PMC10027398.
      View in: PubMed   Mentions: 24     Fields:    Translation:Humans
    234. Epigenetically mediated electrocardiographic manifestations of sub-chronic exposures to ambient particulate matter air pollution in the Women's Health Initiative and Atherosclerosis Risk in Communities Study. Environ Res. 2021 07; 198:111211. Gondalia R, Baldassari A, Holliday KM, Justice AE, Stewart JD, Liao D, Yanosky JD, Engel SM, Sheps D, Jordahl KM, Bhatti P, Horvath S, Assimes TL, Demerath EW, Guan W, Fornage M, Bressler J, North KE, Conneely KN, Li Y, Hou L, Baccarelli AA, Whitsel EA. PMID: 33895111; PMCID: PMC8179344.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansPHPublic Health
    235. Epigenetic clock and methylation study of oocytes from a bovine model of reproductive aging. Aging Cell. 2021 05; 20(5):e13349. Kordowitzki P, Haghani A, Zoller JA, Li CZ, Raj K, Spangler ML, Horvath S. PMID: 33797841; PMCID: PMC8135012.
      View in: PubMed   Mentions: 32     Fields:    Translation:HumansAnimalsCells
    236. Incorporation of a nucleoside analog maps genome repair sites in postmitotic human neurons. Science. 2021 04 02; 372(6537):91-94. Reid DA, Reed PJ, Schlachetzki JCM, Nitulescu II, Chou G, Tsui EC, Jones JR, Chandran S, Lu AT, McClain CA, Ooi JH, Wang TW, Lana AJ, Linker SB, Ricciardulli AS, Lau S, Schafer ST, Horvath S, Dixon JR, Hah N, Glass CK, Gage FH. PMID: 33795458; PMCID: PMC9179101.
      View in: PubMed   Mentions: 67     Fields:    Translation:HumansCells
    237. The Effects of Lifetime Estrogen Exposure on Breast Epigenetic Age. Cancer Epidemiol Biomarkers Prev. 2021 06; 30(6):1241-1249. Sehl ME, Henry JE, Storniolo AM, Horvath S, Ganz PA. PMID: 33771849; PMCID: PMC8172523.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansCells
    238. DNA methylation biomarker for cumulative lead exposure is associated with Parkinson's disease. Clin Epigenetics. 2021 03 22; 13(1):59. Paul KC, Horvath S, Del Rosario I, Bronstein JM, Ritz B. PMID: 33752746; PMCID: PMC7983295.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansCells
    239. DNA methylation predicts age and provides insight into exceptional longevity of bats. Nat Commun. 2021 03 12; 12(1):1615. Wilkinson GS, Adams DM, Haghani A, Lu AT, Zoller J, Breeze CE, Arnold BD, Ball HC, Carter GG, Cooper LN, Dechmann DKN, Devanna P, Fasel NJ, Galazyuk AV, Günther L, Hurme E, Jones G, Knörnschild M, Lattenkamp EZ, Li CZ, Mayer F, Reinhardt JA, Medellin RA, Nagy M, Pope B, Power ML, Ransome RD, Teeling EC, Vernes SC, Zamora-Mejías D, Zhang J, Faure PA, Greville LJ, Herrera M LG, Flores-Martínez JJ, Horvath S. PMID: 33712580; PMCID: PMC7955057.
      View in: PubMed   Mentions: 89     Fields:    Translation:AnimalsCells
    240. Long-term maturation of human cortical organoids matches key early postnatal transitions. Nat Neurosci. 2021 03; 24(3):331-342. Gordon A, Yoon SJ, Tran SS, Makinson CD, Park JY, Andersen J, Valencia AM, Horvath S, Xiao X, Huguenard JR, Pa?ca SP, Geschwind DH. PMID: 33619405; PMCID: PMC8109149.
      View in: PubMed   Mentions: 196     Fields:    Translation:HumansCells
    241. Accelerated epigenetic aging in adolescents living with HIV is associated with altered development of brain structures. J Neurovirol. 2022 04; 28(2):208-216. Hoare J, Stein DJ, Heany SJ, Fouche JP, Phillips N, Er S, Myer L, Zar HJ, Horvath S, Levine AJ. PMID: 33554325; PMCID: PMC8346577.
      View in: PubMed   Mentions: 16     Fields:    Translation:Humans
    242. An epigenetic clock to estimate the age of living beluga whales. Evol Appl. 2021 May; 14(5):1263-1273. Bors EK, Baker CS, Wade PR, O'Neill KB, Shelden KEW, Thompson MJ, Fei Z, Jarman S, Horvath S. PMID: 34025766; PMCID: PMC8127720.
      View in: PubMed   Mentions: 21  
    243. Early life adversity, pubertal timing, and epigenetic age acceleration in adulthood. Dev Psychobiol. 2021 07; 63(5):890-902. Hamlat EJ, Prather AA, Horvath S, Belsky J, Epel ES. PMID: 33423276; PMCID: PMC8271092.
      View in: PubMed   Mentions: 58     Fields:    Translation:HumansCells
    244. ARDD 2020: from aging mechanisms to interventions. Aging (Albany NY). 2020 12 30; 12(24):24484-24503. Mkrtchyan GV, Abdelmohsen K, Andreux P, Bagdonaite I, Barzilai N, Brunak S, Cabreiro F, de Cabo R, Campisi J, Cuervo AM, Demaria M, Ewald CY, Fang EF, Faragher R, Ferrucci L, Freund A, Silva-García CG, Georgievskaya A, Gladyshev VN, Glass DJ, Gorbunova V, de Grey A, He WW, Hoeijmakers J, Hoffmann E, Horvath S, Houtkooper RH, Jensen MK, Jensen MB, Kane A, Kassem M, de Keizer P, Kennedy B, Karsenty G, Lamming DW, Lee KF, MacAulay N, Mamoshina P, Mellon J, Molenaars M, Moskalev A, Mund A, Niedernhofer L, Osborne B, Pak HH, Parkhitko A, Raimundo N, Rando TA, Rasmussen LJ, Reis C, Riedel CG, Franco-Romero A, Schumacher B, Sinclair DA, Suh Y, Taub PR, Toiber D, Treebak JT, Valenzano DR, Verdin E, Vijg J, Young S, Zhang L, Bakula D, Zhavoronkov A, Scheibye-Knudsen M. PMID: 33378272; PMCID: PMC7803558.
      View in: PubMed   Mentions: 26     Fields:    Translation:Humans
    245. Reprogramming to recover youthful epigenetic information and restore vision. Nature. 2020 12; 588(7836):124-129. Lu Y, Brommer B, Tian X, Krishnan A, Meer M, Wang C, Vera DL, Zeng Q, Yu D, Bonkowski MS, Yang JH, Zhou S, Hoffmann EM, Karg MM, Schultz MB, Kane AE, Davidsohn N, Korobkina E, Chwalek K, Rajman LA, Church GM, Hochedlinger K, Gladyshev VN, Horvath S, Levine ME, Gregory-Ksander MS, Ksander BR, He Z, Sinclair DA. PMID: 33268865; PMCID: PMC7752134.
      View in: PubMed   Mentions: 401     Fields:    Translation:HumansAnimalsCells
    246. The Effects of Anti-retroviral Therapy on Epigenetic Age Acceleration Observed in HIV-1-infected Adults. Pathog Immun. 2020; 5(1):291-311. Sehl ME, Rickabaugh TM, Shih R, Martinez-Maza O, Horvath S, Ramirez CM, Jamieson BD. PMID: 33501399; PMCID: PMC7815056.
      View in: PubMed   Mentions: 21  
    247. Epigenetic mutation load is weakly correlated with epigenetic age acceleration. Aging (Albany NY). 2020 Sep 29; 12(18):17863-17894. Yan Q, Paul KC, Lu AT, Kusters C, Binder AM, Horvath S, Ritz B. PMID: 32991324; PMCID: PMC7585066.
      View in: PubMed   Mentions: 17     Fields:    
    248. DNA methylation study of Huntington's disease and motor progression in patients and in animal models. Nat Commun. 2020 09 10; 11(1):4529. Lu AT, Narayan P, Grant MJ, Langfelder P, Wang N, Kwak S, Wilkinson H, Chen RZ, Chen J, Simon Bawden C, Rudiger SR, Ciosi M, Chatzi A, Maxwell A, Hore TA, Aaronson J, Rosinski J, Preiss A, Vogt TF, Coppola G, Monckton D, Snell RG, William Yang X, Horvath S. PMID: 32913184; PMCID: PMC7484780.
      View in: PubMed   Mentions: 39     Fields:    Translation:HumansAnimalsCells
    249. Analysis of epigenetic aging in vivo and in vitro: Factors controlling the speed and direction. Exp Biol Med (Maywood). 2020 11; 245(17):1543-1551. Matsuyama M, Søraas A, Yu S, Kim K, Stavrou EX, Caimi PF, Wald D, deLima M, Dahl JA, Horvath S, Matsuyama S. PMID: 32762265; PMCID: PMC7787543.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimalsCells
    250. Epigenetic age and pregnancy outcomes: GrimAge acceleration is associated with shorter gestational length and lower birthweight. Clin Epigenetics. 2020 08 06; 12(1):120. Ross KM, Carroll JE, Horvath S, Hobel CJ, Coussons-Read ME, Dunkel Schetter C. PMID: 32762768; PMCID: PMC7409637.
      View in: PubMed   Mentions: 21     Fields:    Translation:Humans
    251. Correction to: A candidate gene study of intermediate histopathological phenotypes in HIV-associated neurocognitive disorders. J Neurovirol. 2020 08; 26(4):509-510. Levine AJ, Soontornniyomkij V, Masliah E, Sinsheimer JS, Ji SS, Horvath S, Singer EJ, Kallianpur A, Moore DJ. PMID: 32632672.
      View in: PubMed   Mentions: 1     Fields:    
    252. Epigenetic measures of ageing predict the prevalence and incidence of leading causes of death and disease burden. Clin Epigenetics. 2020 07 31; 12(1):115. Hillary RF, Stevenson AJ, McCartney DL, Campbell A, Walker RM, Howard DM, Ritchie CW, Horvath S, Hayward C, McIntosh AM, Porteous DJ, Deary IJ, Evans KL, Marioni RE. PMID: 32736664; PMCID: PMC7394682.
      View in: PubMed   Mentions: 116     Fields:    Translation:Humans
    253. Blood DNA methylation sites predict death risk in a longitudinal study of 12, 300 individuals. Aging (Albany NY). 2020 07 22; 12(14):14092-14124. Colicino E, Marioni R, Ward-Caviness C, Gondalia R, Guan W, Chen B, Tsai PC, Huan T, Xu G, Golareh A, Schwartz J, Vokonas P, Just A, Starr JM, McRae AF, Wray NR, Visscher PM, Bressler J, Zhang W, Tanaka T, Moore AZ, Pilling LC, Zhang G, Stewart JD, Li Y, Hou L, Castillo-Fernandez J, Spector T, Kiel DP, Murabito JM, Liu C, Mendelson M, Assimes T, Absher D, Tsaho PS, Lu AT, Ferrucci L, Wilson R, Waldenberger M, Prokisch H, Bandinelli S, Bell JT, Levy D, Deary IJ, Horvath S, Pankow J, Peters A, Whitsel EA, Baccarelli A. PMID: 32697766; PMCID: PMC7425458.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansCells
    254. Accelerated epigenetic aging in adolescents from low-income households is associated with altered development of brain structures. Metab Brain Dis. 2020 12; 35(8):1287-1298. Hoare J, Stein DJ, Heany SJ, Fouche JP, Phillips N, Er S, Myer L, Zar HJ, Horvath S, Levine AJ. PMID: 32671535; PMCID: PMC7606536.
      View in: PubMed   Mentions: 13     Fields:    Translation:Humans
    255. DNA Methylation Age Is More Closely Associated With Infection Risk Than Chronological Age in Kidney Transplant Recipients. Transplant Direct. 2020 Aug; 6(8):e576. Schaenman J, Zhou X, Guo R, Rossetti M, Liang EC, Lum E, Abdalla B, Bunnapradist S, Pham PT, Danovitch G, Karlamangla A, Reed E, Horvath S, Elashoff D. PMID: 33134500; PMCID: PMC7581059.
      View in: PubMed   Mentions: 10  
    256. An epigenome-wide association study of ambient pyrethroid pesticide exposures in California's central valley. Int J Hyg Environ Health. 2020 08; 229:113569. Furlong MA, Paul KC, Yan Q, Chuang YH, Cockburn MG, Bronstein JM, Horvath S, Ritz B. PMID: 32679516; PMCID: PMC7492449.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansCellsPHPublic Health
    257. The acute effects of adjuvant radiation and chemotherapy on peripheral blood epigenetic age in early stage breast cancer patients. NPJ Breast Cancer. 2020; 6:23. Sehl ME, Carroll JE, Horvath S, Bower JE. PMID: 32566744; PMCID: PMC7293278.
      View in: PubMed   Mentions: 51  
    258. A candidate gene study of intermediate histopathological phenotypes in HIV-associated neurocognitive disorders. J Neurovirol. 2020 08; 26(4):496-508. Levine AJ, Soontornniyomkij V, Masliah E, Sinsheimer JS, Ji SS, Horvath S, Singer EJ, Kallianpur A, Moore DJ. PMID: 32394397; PMCID: PMC7442707.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    259. Current perspectives on the cellular and molecular features of epigenetic ageing. Exp Biol Med (Maywood). 2020 11; 245(17):1532-1542. Raj K, Horvath S. PMID: 32276545; PMCID: PMC7787550.
      View in: PubMed   Mentions: 42     Fields:    Translation:HumansAnimalsCells
    260. Vasomotor Symptoms and Accelerated Epigenetic Aging in the Women's Health Initiative (WHI). J Clin Endocrinol Metab. 2020 04 01; 105(4). Thurston RC, Carroll JE, Levine M, Chang Y, Crandall C, Manson JE, Pal L, Hou L, Shadyab AH, Horvath S. PMID: 32080740; PMCID: PMC7069347.
      View in: PubMed   Mentions: 13     Fields:    Translation:Humans
    261. Transient non-integrative expression of nuclear reprogramming factors promotes multifaceted amelioration of aging in human cells. Nat Commun. 2020 03 24; 11(1):1545. Sarkar TJ, Quarta M, Mukherjee S, Colville A, Paine P, Doan L, Tran CM, Chu CR, Horvath S, Qi LS, Bhutani N, Rando TA, Sebastiano V. PMID: 32210226; PMCID: PMC7093390.
      View in: PubMed   Mentions: 154     Fields:    Translation:HumansAnimalsCells
    262. Immune epigenetic age in pregnancy and 1 year after birth: Associations with weight change. Am J Reprod Immunol. 2020 05; 83(5):e13229. Ross KM, Carroll J, Horvath S, Hobel CJ, Coussons-Read ME, Dunkel Schetter C. PMID: 32061136; PMCID: PMC8401279.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansCells
    263. Estimating breast tissue-specific DNA methylation age using next-generation sequencing data. Clin Epigenetics. 2020 03 12; 12(1):45. Castle JR, Lin N, Liu J, Storniolo AMV, Shendre A, Hou L, Horvath S, Liu Y, Wang C, He C. PMID: 32164769; PMCID: PMC7282053.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansCells
    264. Analysis of DNA methylation associates the cystine-glutamate antiporter SLC7A11 with risk of Parkinson's disease. Nat Commun. 2020 03 06; 11(1):1238. Vallerga CL, Zhang F, Fowdar J, McRae AF, Qi T, Nabais MF, Zhang Q, Kassam I, Henders AK, Wallace L, Montgomery G, Chuang YH, Horvath S, Ritz B, Halliday G, Hickie I, Kwok JB, Pearson J, Pitcher T, Kennedy M, Bentley SR, Silburn PA, Yang J, Wray NR, Lewis SJG, Anderson T, Dalrymple-Alford J, Mellick GD, Visscher PM, Gratten J. PMID: 32144264; PMCID: PMC7060318.
      View in: PubMed   Mentions: 80     Fields:    Translation:HumansCells
    265. Coagulation factor VIII: Relationship to cardiovascular disease risk and whole genome sequence and epigenome-wide analysis in African Americans. J Thromb Haemost. 2020 06; 18(6):1335-1347. Raffield LM, Lu AT, Szeto MD, Little A, Grinde KE, Shaw J, Auer PL, Cushman M, Horvath S, Irvin MR, Lange EM, Lange LA, Nickerson DA, Thornton TA, Wilson JG, Wheeler MM, NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium, TOPMed Hematology & Hemostasis Working, Zakai NA, Reiner AP. PMID: 31985870; PMCID: PMC7274883.
      View in: PubMed   Mentions: 16     Fields:    Translation:Humans
    266. An epigenetic clock for human skeletal muscle. J Cachexia Sarcopenia Muscle. 2020 08; 11(4):887-898. Voisin S, Harvey NR, Haupt LM, Griffiths LR, Ashton KJ, Coffey VG, Doering TM, Thompson JM, Benedict C, Cedernaes J, Lindholm ME, Craig JM, Rowlands DS, Sharples AP, Horvath S, Eynon N. PMID: 32067420; PMCID: PMC7432573.
      View in: PubMed   Mentions: 58     Fields:    Translation:Humans
    267. Leukocyte Traits and Exposure to Ambient Particulate Matter Air Pollution in the Women's Health Initiative and Atherosclerosis Risk in Communities Study. Environ Health Perspect. 2020 01; 128(1):17004. Gondalia R, Holliday KM, Baldassari A, Justice AE, Stewart JD, Liao D, Yanosky JD, Engel SM, Jordahl KM, Bhatti P, Horvath S, Assimes TL, Pankow JS, Demerath EW, Guan W, Fornage M, Bressler J, North KE, Conneely KN, Li Y, Hou L, Baccarelli AA, Whitsel EA. PMID: 31903802; PMCID: PMC7015624.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCellsPHPublic Health
    268. An epigenetic predictor of death captures multi-modal measures of brain health. Mol Psychiatry. 2021 08; 26(8):3806-3816. Hillary RF, Stevenson AJ, Cox SR, McCartney DL, Harris SE, Seeboth A, Higham J, Sproul D, Taylor AM, Redmond P, Corley J, Pattie A, Hernández MDCV, Muñoz-Maniega S, Bastin ME, Wardlaw JM, Horvath S, Ritchie CW, Spires-Jones TL, McIntosh AM, Evans KL, Deary IJ, Marioni RE. PMID: 31796892; PMCID: PMC8550950.
      View in: PubMed   Mentions: 81     Fields:    Translation:HumansCells
    269. DNA Methylation Analysis Validates Organoids as a Viable Model for Studying Human Intestinal Aging. Cell Mol Gastroenterol Hepatol. 2020; 9(3):527-541. Lewis SK, Nachun D, Martin MG, Horvath S, Coppola G, Jones DL. PMID: 31805439; PMCID: PMC7044532.
      View in: PubMed   Mentions: 45     Fields:    Translation:HumansCells
    270. DNA methylation aging clocks: challenges and recommendations. Genome Biol. 2019 11 25; 20(1):249. Bell CG, Lowe R, Adams PD, Baccarelli AA, Beck S, Bell JT, Christensen BC, Gladyshev VN, Heijmans BT, Horvath S, Ideker T, Issa JJ, Kelsey KT, Marioni RE, Reik W, Relton CL, Schalkwyk LC, Teschendorff AE, Wagner W, Zhang K, Rakyan VK. PMID: 31767039; PMCID: PMC6876109.
      View in: PubMed   Mentions: 540     Fields:    Translation:HumansAnimalsCells
    271. Psychosocial stress and epigenetic aging. Int Rev Neurobiol. 2020; 150:107-128. Palma-Gudiel H, Fañanás L, Horvath S, Zannas AS. PMID: 32204828.
      View in: PubMed   Mentions: 63     Fields:    Translation:Humans
    272. A meta-analysis of genome-wide association studies of epigenetic age acceleration. PLoS Genet. 2019 11; 15(11):e1008104. Gibson J, Russ TC, Clarke TK, Howard DM, Hillary RF, Evans KL, Walker RM, Bermingham ML, Morris SW, Campbell A, Hayward C, Murray AD, Porteous DJ, Horvath S, Lu AT, McIntosh AM, Whalley HC, Marioni RE. PMID: 31738745; PMCID: PMC6886870.
      View in: PubMed   Mentions: 68     Fields:    Translation:HumansCells
    273. Epigenetic age acceleration and metabolic syndrome in the coronary artery risk development in young adults study. Clin Epigenetics. 2019 11 15; 11(1):160. Nannini DR, Joyce BT, Zheng Y, Gao T, Liu L, Yoon G, Huan T, Ma J, Jacobs DR, Wilkins JT, Ren J, Zhang K, Khan SS, Allen NB, Horvath S, Lloyd-Jones DM, Greenland P, Hou L. PMID: 31730017; PMCID: PMC6858654.
      View in: PubMed   Mentions: 48     Fields:    Translation:HumansCells
    274. The PedBE clock accurately estimates DNA methylation age in pediatric buccal cells. Proc Natl Acad Sci U S A. 2020 09 22; 117(38):23329-23335. McEwen LM, O'Donnell KJ, McGill MG, Edgar RD, Jones MJ, MacIsaac JL, Lin DTS, Ramadori K, Morin A, Gladish N, Garg E, Unternaehrer E, Pokhvisneva I, Karnani N, Kee MZL, Klengel T, Adler NE, Barr RG, Letourneau N, Giesbrecht GF, Reynolds JN, Czamara D, Armstrong JM, Essex MJ, de Weerth C, Beijers R, Tollenaar MS, Bradley B, Jovanovic T, Ressler KJ, Steiner M, Entringer S, Wadhwa PD, Buss C, Bush NR, Binder EB, Boyce WT, Meaney MJ, Horvath S, Kobor MS. PMID: 31611402; PMCID: PMC7519312.
      View in: PubMed   Mentions: 154     Fields:    Translation:HumansCells
    275. Reversal of epigenetic aging and immunosenescent trends in humans. Aging Cell. 2019 12; 18(6):e13028. Fahy GM, Brooke RT, Watson JP, Good Z, Vasanawala SS, Maecker H, Leipold MD, Lin DTS, Kobor MS, Horvath S. PMID: 31496122; PMCID: PMC6826138.
      View in: PubMed   Mentions: 266     Fields:    Translation:Humans
    276. Epigenetic aging is accelerated in alcohol use disorder and regulated by genetic variation in APOL2. Neuropsychopharmacology. 2020 01; 45(2):327-336. Luo A, Jung J, Longley M, Rosoff DB, Charlet K, Muench C, Lee J, Hodgkinson CA, Goldman D, Horvath S, Kaminsky ZA, Lohoff FW. PMID: 31466081; PMCID: PMC6901591.
      View in: PubMed   Mentions: 54     Fields:    Translation:HumansCells
    277. Epigenome-wide association study of leukocyte telomere length. Aging (Albany NY). 2019 08 26; 11(16):5876-5894. Lee Y, Sun D, Ori APS, Lu AT, Seeboth A, Harris SE, Deary IJ, Marioni RE, Soerensen M, Mengel-From J, Hjelmborg J, Christensen K, Wilson JG, Levy D, Reiner AP, Chen W, Li S, Harris JR, Magnus P, Aviv A, Jugessur A, Horvath S. PMID: 31461406; PMCID: PMC6738430.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansCells
    278. DNA methylation-based estimator of telomere length. Aging (Albany NY). 2019 08 18; 11(16):5895-5923. Lu AT, Seeboth A, Tsai PC, Sun D, Quach A, Reiner AP, Kooperberg C, Ferrucci L, Hou L, Baccarelli AA, Li Y, Harris SE, Corley J, Taylor A, Deary IJ, Stewart JD, Whitsel EA, Assimes TL, Chen W, Li S, Mangino M, Bell JT, Wilson JG, Aviv A, Marioni RE, Raj K, Horvath S. PMID: 31422385; PMCID: PMC6738410.
      View in: PubMed   Mentions: 244     Fields:    Translation:HumansCells
    279. Optimism is not associated with two indicators of DNA methylation aging. Aging (Albany NY). 2019 07 18; 11(14):4970-4989. Kim ES, Fong K, Lee L, Spiro A, Schwartz J, Whitsel E, Horvath S, Wang C, Hou L, Baccarelli AA, Li Y, Stewart J, Manson JE, Grodstein F, DeMeo DL, Kubzansky LD. PMID: 31322503; PMCID: PMC6682522.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
    280. Placental epigenetic clocks: estimating gestational age using placental DNA methylation levels. Aging (Albany NY). 2019 06 24; 11(12):4238-4253. Lee Y, Choufani S, Weksberg R, Wilson SL, Yuan V, Burt A, Marsit C, Lu AT, Ritz B, Bohlin J, Gjessing HK, Harris JR, Magnus P, Binder AM, Robinson WP, Jugessur A, Horvath S. PMID: 31235674; PMCID: PMC6628997.
      View in: PubMed   Mentions: 83     Fields:    Translation:HumansCells
    281. Methylome-wide association study provides evidence of particulate matter air pollution-associated DNA methylation. Environ Int. 2019 11; 132:104723. Gondalia R, Baldassari A, Holliday KM, Justice AE, Méndez-Giráldez R, Stewart JD, Liao D, Yanosky JD, Brennan KJM, Engel SM, Jordahl KM, Kennedy E, Ward-Caviness CK, Wolf K, Waldenberger M, Cyrys J, Peters A, Bhatti P, Horvath S, Assimes TL, Pankow JS, Demerath EW, Guan W, Fornage M, Bressler J, North KE, Conneely KN, Li Y, Hou L, Baccarelli AA, Whitsel EA. PMID: 31208937; PMCID: PMC6754789.
      View in: PubMed   Mentions: 45     Fields:    Translation:HumansCells
    282. Human aging DNA methylation signatures are conserved but accelerated in cultured fibroblasts. Epigenetics. 2019 10; 14(10):961-976. Sturm G, Cardenas A, Bind MA, Horvath S, Wang S, Wang Y, Hägg S, Hirano M, Picard M. PMID: 31156022; PMCID: PMC6691995.
      View in: PubMed   Mentions: 35     Fields:    Translation:HumansCells
    283. Rapamycin retards epigenetic ageing of keratinocytes independently of its effects on replicative senescence, proliferation and differentiation. Aging (Albany NY). 2019 05 26; 11(10):3238-3249. Horvath S, Lu AT, Cohen H, Raj K. PMID: 31136303; PMCID: PMC6555449.
      View in: PubMed   Mentions: 34     Fields:    Translation:HumansCells
    284. Epigenetic clock analysis of human fibroblasts in vitro: effects of hypoxia, donor age, and expression of hTERT and SV40 largeT. Aging (Albany NY). 2019 05 21; 11(10):3012-3022. Matsuyama M, WuWong DJ, Horvath S, Matsuyama S. PMID: 31113906; PMCID: PMC6555444.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansCells
    285. Synchrony and asynchrony between an epigenetic clock and developmental timing. Sci Rep. 2019 03 06; 9(1):3770. Hoshino A, Horvath S, Sridhar A, Chitsazan A, Reh TA. PMID: 30842553; PMCID: PMC6403397.
      View in: PubMed   Mentions: 22     Fields:    Translation:HumansCells
    286. Correction: A new aging measure captures morbidity and mortality risk across diverse subpopulations from NHANES IV: A cohort study. PLoS Med. 2019 Feb; 16(2):e1002760. Liu Z, Kuo PL, Horvath S, Crimmins E, Ferrucci L, Levine M. PMID: 30802240; PMCID: PMC6388911.
      View in: PubMed   Mentions: 23     Fields:    
    287. The role of epigenetic aging in education and racial/ethnic mortality disparities among older U.S. Women. Psychoneuroendocrinology. 2019 06; 104:18-24. Liu Z, Chen BH, Assimes TL, Ferrucci L, Horvath S, Levine ME. PMID: 30784901; PMCID: PMC6555423.
      View in: PubMed   Mentions: 44     Fields:    Translation:Humans
    288. Epigenetic age is a cell-intrinsic property in transplanted human hematopoietic cells. Aging Cell. 2019 04; 18(2):e12897. Søraas A, Matsuyama M, de Lima M, Wald D, Buechner J, Gedde-Dahl T, Søraas CL, Chen B, Ferrucci L, Dahl JA, Horvath S, Matsuyama S. PMID: 30712319; PMCID: PMC6413751.
      View in: PubMed   Mentions: 33     Fields:    Translation:HumansCells
    289. DNA methylation patterns of adult survivors of adolescent/young adult Hodgkin lymphoma compared to their unaffected monozygotic twin. Leuk Lymphoma. 2019 06; 60(6):1429-1437. Wang J, Van Den Berg D, Hwang AE, Weisenberger D, Triche T, Nathwani BN, Conti DV, Siegmund K, Mack TM, Horvath S, Cozen W. PMID: 30668190; PMCID: PMC7781082.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansCells
    290. DNA methylation GrimAge strongly predicts lifespan and healthspan. Aging (Albany NY). 2019 01 21; 11(2):303-327. Lu AT, Quach A, Wilson JG, Reiner AP, Aviv A, Raj K, Hou L, Baccarelli AA, Li Y, Stewart JD, Whitsel EA, Assimes TL, Ferrucci L, Horvath S. PMID: 30669119; PMCID: PMC6366976.
      View in: PubMed   Mentions: 1357     Fields:    Translation:HumansCells
    291. Longitudinal Epigenome-Wide Methylation Study of Cognitive Decline and Motor Progression in Parkinson's Disease. J Parkinsons Dis. 2019; 9(2):389-400. Chuang YH, Lu AT, Paul KC, Folle AD, Bronstein JM, Bordelon Y, Horvath S, Ritz B. PMID: 30958317; PMCID: PMC6946688.
      View in: PubMed   Mentions: 31     Fields:    Translation:HumansCells
    292. Tracking the Epigenetic Clock Across the Human Life Course: A Meta-analysis of Longitudinal Cohort Data. J Gerontol A Biol Sci Med Sci. 2019 01 01; 74(1):57-61. Marioni RE, Suderman M, Chen BH, Horvath S, Bandinelli S, Morris T, Beck S, Ferrucci L, Pedersen NL, Relton CL, Deary IJ, Hägg S. PMID: 29718110; PMCID: PMC6298183.
      View in: PubMed   Mentions: 61     Fields:    Translation:HumansCells
    293. A new aging measure captures morbidity and mortality risk across diverse subpopulations from NHANES IV: A cohort study. PLoS Med. 2018 12; 15(12):e1002718. Liu Z, Kuo PL, Horvath S, Crimmins E, Ferrucci L, Levine M. PMID: 30596641; PMCID: PMC6312200.
      View in: PubMed   Mentions: 339     Fields:    Translation:HumansPHPublic Health
    294. Cell and tissue type independent age-associated DNA methylation changes are not rare but common. Aging (Albany NY). 2018 11 27; 10(11):3541-3557. Zhu T, Zheng SC, Paul DS, Horvath S, Teschendorff AE. PMID: 30482885; PMCID: PMC6286821.
      View in: PubMed   Mentions: 38     Fields:    Translation:HumansCells
    295. A multi-tissue full lifespan epigenetic clock for mice. Aging (Albany NY). 2018 10 21; 10(10):2832-2854. Thompson MJ, Chwialkowska K, Rubbi L, Lusis AJ, Davis RC, Srivastava A, Korstanje R, Churchill GA, Horvath S, Pellegrini M. PMID: 30348905; PMCID: PMC6224226.
      View in: PubMed   Mentions: 115     Fields:    Translation:AnimalsCells
    296. Epigenetic ageing is distinct from senescence-mediated ageing and is not prevented by telomerase expression. Aging (Albany NY). 2018 10 17; 10(10):2800-2815. Kabacik S, Horvath S, Cohen H, Raj K. PMID: 30332397; PMCID: PMC6224244.
      View in: PubMed   Mentions: 43     Fields:    Translation:HumansCells
    297. Systematic evaluation of DNA methylation age estimation with common preprocessing methods and the Infinium MethylationEPIC BeadChip array. Clin Epigenetics. 2018 10 16; 10(1):123. McEwen LM, Jones MJ, Lin DTS, Edgar RD, Husquin LT, MacIsaac JL, Ramadori KE, Morin AM, Rider CF, Carlsten C, Quintana-Murci L, Horvath S, Kobor MS. PMID: 30326963; PMCID: PMC6192219.
      View in: PubMed   Mentions: 91     Fields:    Translation:HumansCells
    298. DNA methylation age is accelerated in alcohol dependence. Transl Psychiatry. 2018 09 05; 8(1):182. Rosen AD, Robertson KD, Hlady RA, Muench C, Lee J, Philibert R, Horvath S, Kaminsky ZA, Lohoff FW. PMID: 30185790; PMCID: PMC6125381.
      View in: PubMed   Mentions: 60     Fields:    Translation:HumansCells
    299. Increased epigenetic age in normal breast tissue from luminal breast cancer patients. Clin Epigenetics. 2018 08 29; 10(1):112. Hofstatter EW, Horvath S, Dalela D, Gupta P, Chagpar AB, Wali VB, Bossuyt V, Storniolo AM, Hatzis C, Patwardhan G, Von Wahlde MK, Butler M, Epstein L, Stavris K, Sturrock T, Au A, Kwei S, Pusztai L. PMID: 30157950; PMCID: PMC6114717.
      View in: PubMed   Mentions: 34     Fields:    Translation:HumansCells
    300. Intraindividual variability in neurocognitive performance: No influence due to HIV status or self-reported effort. J Clin Exp Neuropsychol. 2018 12; 40(10):1044-1049. Levine AJ, Martin E, Munro CA, Sacktor N, Horvath S, Becker JT, Multicenter AIDS Cohort Study–Neuropsychology Working Group. PMID: 30124355; PMCID: PMC6294568.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    301. Breast cancer treatment and its effects on aging. J Geriatr Oncol. 2019 03; 10(2):346-355. Chang L, Weiner LS, Hartman SJ, Horvath S, Jeste D, Mischel PS, Kado DM. PMID: 30078714; PMCID: PMC7062379.
      View in: PubMed   Mentions: 38     Fields:    Translation:Humans
    302. Author Correction: Genome-wide changes in lncRNA, splicing, and regional gene expression patterns in autism. Nature. 2018 08; 560(7718):E30. Parikshak NN, Swarup V, Belgard TG, Irimia M, Ramaswami G, Gandal MJ, Hartl C, Leppa V, de la Torre Ubieta L, Huang J, Lowe JK, Blencowe BJ, Horvath S, Geschwind DH. PMID: 29995847.
      View in: PubMed   Mentions: 4     Fields:    
    303. Epigenetic clock for skin and blood cells applied to Hutchinson Gilford Progeria Syndrome and ex vivo studies. Aging (Albany NY). 2018 Jul 26; 10(7):1758-1775. Horvath S, Oshima J, Martin GM, Lu AT, Quach A, Cohen H, Felton S, Matsuyama M, Lowe D, Kabacik S, Wilson JG, Reiner AP, Maierhofer A, Flunkert J, Aviv A, Hou L, Baccarelli AA, Li Y, Stewart JD, Whitsel EA, Ferrucci L, Matsuyama S, Raj K. PMID: 30048243; PMCID: PMC6075434.
      View in: PubMed   Mentions: 441     Fields:    Translation:HumansCells
    304. Organophosphate pesticide exposure and differential genome-wide DNA methylation. Sci Total Environ. 2018 Dec 15; 645:1135-1143. Paul KC, Chuang YH, Cockburn M, Bronstein JM, Horvath S, Ritz B. PMID: 30248838; PMCID: PMC6400463.
      View in: PubMed   Mentions: 35     Fields:    Translation:HumansCellsPHPublic Health
    305. Perinatally acquired HIV infection accelerates epigenetic aging in South African adolescents. AIDS. 2018 07 17; 32(11):1465-1474. Horvath S, Stein DJ, Phillips N, Heany SJ, Kobor MS, Lin DTS, Myer L, Zar HJ, Levine AJ, Hoare J. PMID: 29746298; PMCID: PMC6026068.
      View in: PubMed   Mentions: 53     Fields:    Translation:HumansCells
    306. Genetic and epigenetic changes in clonal descendants of irradiated human fibroblasts. Exp Cell Res. 2018 09 15; 370(2):322-332. Flunkert J, Maierhofer A, Dittrich M, Müller T, Horvath S, Nanda I, Haaf T. PMID: 29964050.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansCells
    307. DNA methylation-based biomarkers and the epigenetic clock theory of ageing. Nat Rev Genet. 2018 06; 19(6):371-384. Horvath S, Raj K. PMID: 29643443.
      View in: PubMed   Mentions: 1592     Fields:    Translation:HumansAnimalsCells
    308. An epigenetic biomarker of aging for lifespan and healthspan. Aging (Albany NY). 2018 04 18; 10(4):573-591. Levine ME, Lu AT, Quach A, Chen BH, Assimes TL, Bandinelli S, Hou L, Baccarelli AA, Stewart JD, Li Y, Whitsel EA, Wilson JG, Reiner AP, Aviv A, Lohman K, Liu Y, Ferrucci L, Horvath S. PMID: 29676998; PMCID: PMC5940111.
      View in: PubMed   Mentions: 1905     Fields:    Translation:Humans
    309. Metabolic and inflammatory biomarkers are associated with epigenetic aging acceleration estimates in the GOLDN study. Clin Epigenetics. 2018; 10:56. Irvin MR, Aslibekyan S, Do A, Zhi D, Hidalgo B, Claas SA, Srinivasasainagendra V, Horvath S, Tiwari HK, Absher DM, Arnett DK. PMID: 29713391; PMCID: PMC5907301.
      View in: PubMed   Mentions: 63     Fields:    Translation:HumansCells
    310. No reliable gene expression biomarkers of current or impending neurocognitive impairment in peripheral blood monocytes of persons living with HIV. J Neurovirol. 2018 06; 24(3):350-361. Quach A, Horvath S, Nemanim N, Vatakis D, Witt MD, Miller EN, Detels R, Langfelder P, Shapshak P, Singer EJ, Levine AJ. PMID: 29582356; PMCID: PMC6411303.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCells
    311. Faster ticking rate of the epigenetic clock is associated with faster pubertal development in girls. Epigenetics. 2018; 13(1):85-94. Binder AM, Corvalan C, Mericq V, Pereira A, Santos JL, Horvath S, Shepherd J, Michels KB. PMID: 29235933; PMCID: PMC5836971.
      View in: PubMed   Mentions: 69     Fields:    Translation:Humans
    312. Shared molecular neuropathology across major psychiatric disorders parallels polygenic overlap. Science. 2018 02 09; 359(6376):693-697. Gandal MJ, Haney JR, Parikshak NN, Leppa V, Ramaswami G, Hartl C, Schork AJ, Appadurai V, Buil A, Werge TM, Liu C, White KP, CommonMind Consortium, PsychENCODE Consortium, iPSYCH-BROAD Working Group, Horvath S, Geschwind DH. PMID: 29439242; PMCID: PMC5898828.
      View in: PubMed   Mentions: 400     Fields:    Translation:HumansCells
    313. GWAS of epigenetic aging rates in blood reveals a critical role for TERT. Nat Commun. 2018 01 26; 9(1):387. Lu AT, Xue L, Salfati EL, Chen BH, Ferrucci L, Levy D, Joehanes R, Murabito JM, Kiel DP, Tsai PC, Yet I, Bell JT, Mangino M, Tanaka T, McRae AF, Marioni RE, Visscher PM, Wray NR, Deary IJ, Levine ME, Quach A, Assimes T, Tsao PS, Absher D, Stewart JD, Li Y, Reiner AP, Hou L, Baccarelli AA, Whitsel EA, Aviv A, Cardona A, Day FR, Wareham NJ, Perry JRB, Ong KK, Raj K, Lunetta KL, Horvath S. PMID: 29374233; PMCID: PMC5786029.
      View in: PubMed   Mentions: 122     Fields:    Translation:HumansCells
    314. MicroRNA signatures of endogenous Huntingtin CAG repeat expansion in mice. PLoS One. 2018; 13(1):e0190550. Langfelder P, Gao F, Wang N, Howland D, Kwak S, Vogt TF, Aaronson JS, Rosinski J, Coppola G, Horvath S, Yang XW. PMID: 29324753; PMCID: PMC5764268.
      View in: PubMed   Mentions: 28     Fields:    Translation:HumansAnimalsCells
    315. DNA Methylation Analysis Identifies Loci for Blood Pressure Regulation. Am J Hum Genet. 2017 Dec 07; 101(6):888-902. Richard MA, Huan T, Ligthart S, Gondalia R, Jhun MA, Brody JA, Irvin MR, Marioni R, Shen J, Tsai PC, Montasser ME, Jia Y, Syme C, Salfati EL, Boerwinkle E, Guan W, Mosley TH, Bressler J, Morrison AC, Liu C, Mendelson MM, Uitterlinden AG, van Meurs JB, BIOS Consortium, Franco OH, Zhang G, Li Y, Stewart JD, Bis JC, Psaty BM, Chen YI, Kardia SLR, Zhao W, Turner ST, Absher D, Aslibekyan S, Starr JM, McRae AF, Hou L, Just AC, Schwartz JD, Vokonas PS, Menni C, Spector TD, Shuldiner A, Damcott CM, Rotter JI, Palmas W, Liu Y, Paus T, Horvath S, O'Connell JR, Guo X, Pausova Z, Assimes TL, Sotoodehnia N, Smith JA, Arnett DK, Deary IJ, Baccarelli AA, Bell JT, Whitsel E, Dehghan A, Levy D, Fornage M. PMID: 29198723; PMCID: PMC5812919.
      View in: PubMed   Mentions: 148     Fields:    Translation:HumansCells
    316. Neuropathological and transcriptomic characteristics of the aged brain. Elife. 2017 11 09; 6. Miller JA, Guillozet-Bongaarts A, Gibbons LE, Postupna N, Renz A, Beller AE, Sunkin SM, Ng L, Rose SE, Smith KA, Szafer A, Barber C, Bertagnolli D, Bickley K, Brouner K, Caldejon S, Chapin M, Chua ML, Coleman NM, Cudaback E, Cuhaciyan C, Dalley RA, Dee N, Desta T, Dolbeare TA, Dotson NI, Fisher M, Gaudreault N, Gee G, Gilbert TL, Goldy J, Griffin F, Habel C, Haradon Z, Hejazinia N, Hellstern LL, Horvath S, Howard K, Howard R, Johal J, Jorstad NL, Josephsen SR, Kuan CL, Lai F, Lee E, Lee F, Lemon T, Li X, Marshall DA, Melchor J, Mukherjee S, Nyhus J, Pendergraft J, Potekhina L, Rha EY, Rice S, Rosen D, Sapru A, Schantz A, Shen E, Sherfield E, Shi S, Sodt AJ, Thatra N, Tieu M, Wilson AM, Montine TJ, Larson EB, Bernard A, Crane PK, Ellenbogen RG, Keene CD, Lein E. PMID: 29120328; PMCID: PMC5679757.
      View in: PubMed   Mentions: 84     Fields:    Translation:Humans
    317. Leukocyte telomere length, T cell composition and DNA methylation age. Aging (Albany NY). 2017 09 20; 9(9):1983-1995. Chen BH, Carty CL, Kimura M, Kark JD, Chen W, Li S, Zhang T, Kooperberg C, Levy D, Assimes T, Absher D, Horvath S, Reiner AP, Aviv A. PMID: 28930701; PMCID: PMC5636670.
      View in: PubMed   Mentions: 36     Fields:    Translation:HumansCells
    318. Parkinson's disease is associated with DNA methylation levels in human blood and saliva. Genome Med. 2017 08 30; 9(1):76. Chuang YH, Paul KC, Bronstein JM, Bordelon Y, Horvath S, Ritz B. PMID: 28851441; PMCID: PMC5576382.
      View in: PubMed   Mentions: 97     Fields:    Translation:HumansCells
    319. DNA Methylation Profiling of Human Prefrontal Cortex Neurons in Heroin Users Shows Significant Difference between Genomic Contexts of Hyper- and Hypomethylation and a Younger Epigenetic Age. Genes (Basel). 2017 May 30; 8(6). Kozlenkov A, Jaffe AE, Timashpolsky A, Apontes P, Rudchenko S, Barbu M, Byne W, Hurd YL, Horvath S, Dracheva S. PMID: 28556790; PMCID: PMC5485516.
      View in: PubMed   Mentions: 52     Fields:    
    320. Dynamics of epigenetic age following hematopoietic stem cell transplantation. Haematologica. 2017 08; 102(8):e321-e323. Stölzel F, Brosch M, Horvath S, Kramer M, Thiede C, von Bonin M, Ammerpohl O, Middeke M, Schetelig J, Ehninger G, Hampe J, Bornhäuser M. PMID: 28550187; PMCID: PMC5541887.
      View in: PubMed   Mentions: 25     Fields:    Translation:Humans
    321. Genetic architecture of epigenetic and neuronal ageing rates in human brain regions. Nat Commun. 2017 05 18; 8:15353. Lu AT, Hannon E, Levine ME, Crimmins EM, Lunnon K, Mill J, Geschwind DH, Horvath S. PMID: 28516910; PMCID: PMC5454371.
      View in: PubMed   Mentions: 66     Fields:    Translation:HumansCells
    322. The epigenetic clock and physical development during childhood and adolescence: longitudinal analysis from a UK birth cohort. Int J Epidemiol. 2017 04 01; 46(2):549-558. Simpkin AJ, Howe LD, Tilling K, Gaunt TR, Lyttleton O, McArdle WL, Ring SM, Horvath S, Smith GD, Relton CL. PMID: 28089957; PMCID: PMC5722033.
      View in: PubMed   Mentions: 77     Fields:    Translation:HumansCells
    323. Accelerated epigenetic aging in Werner syndrome. Aging (Albany NY). 2017 04; 9(4):1143-1152. Maierhofer A, Flunkert J, Oshima J, Martin GM, Haaf T, Horvath S. PMID: 28377537; PMCID: PMC5425119.
      View in: PubMed   Mentions: 95     Fields:    Translation:HumansCells
    324. Exosomes and Homeostatic Synaptic Plasticity Are Linked to Each other and to Huntington's, Parkinson's, and Other Neurodegenerative Diseases by Database-Enabled Analyses of Comprehensively Curated Datasets. Front Neurosci. 2017; 11:149. Wang JKT, Langfelder P, Horvath S, Palazzolo MJ. PMID: 28611571; PMCID: PMC5374209.
      View in: PubMed   Mentions: 40  
    325. DNA methylation age is elevated in breast tissue of healthy women. Breast Cancer Res Treat. 2017 Jul; 164(1):209-219. Sehl ME, Henry JE, Storniolo AM, Ganz PA, Horvath S. PMID: 28364215; PMCID: PMC5487725.
      View in: PubMed   Mentions: 44     Fields:    Translation:HumansCells
    326. An epigenetic aging clock for dogs and wolves. Aging (Albany NY). 2017 03 28; 9(3):1055-1068. Thompson MJ, vonHoldt B, Horvath S, Pellegrini M. PMID: 28373601; PMCID: PMC5391218.
      View in: PubMed   Mentions: 88     Fields:    Translation:AnimalsCells
    327. Association of genetic variation in the tachykinin receptor 3 locus with hot flashes and night sweats in the Women's Health Initiative Study. Menopause. 2017 03; 24(3):252-261. Crandall CJ, Manson JE, Hohensee C, Horvath S, Wactawski-Wende J, LeBlanc ES, Vitolins MZ, Nassir R, Sinsheimer JS. PMID: 28231077; PMCID: PMC5327841.
      View in: PubMed   Mentions: 27     Fields:    Translation:Humans
    328. DNA methylome analysis identifies accelerated epigenetic ageing associated with postmenopausal breast cancer susceptibility. Eur J Cancer. 2017 04; 75:299-307. Ambatipudi S, Horvath S, Perrier F, Cuenin C, Hernandez-Vargas H, Le Calvez-Kelm F, Durand G, Byrnes G, Ferrari P, Bouaoun L, Sklias A, Chajes V, Overvad K, Severi G, Baglietto L, Clavel-Chapelon F, Kaaks R, Barrdahl M, Boeing H, Trichopoulou A, Lagiou P, Naska A, Masala G, Agnoli C, Polidoro S, Tumino R, Panico S, Dollé M, Peeters PHM, Onland-Moret NC, Sandanger TM, Nøst TH, Weiderpass E, Quirós JR, Agudo A, Rodriguez-Barranco M, Huerta Castaño JM, Barricarte A, Fernández AM, Travis RC, Vineis P, Muller DC, Riboli E, Gunter M, Romieu I, Herceg Z. PMID: 28259012; PMCID: PMC5512160.
      View in: PubMed   Mentions: 122     Fields:    Translation:HumansCells
    329. Longitudinal study of surrogate aging measures during human immunodeficiency virus seroconversion. Aging (Albany NY). 2017 02 23; 9(3):687-705. Leung JM, Fishbane N, Jones M, Morin A, Xu S, Liu JC, MacIsaac J, Milloy MJ, Hayashi K, Montaner J, Horvath S, Kobor M, Sin DD, Harrigan PR, Man SF. PMID: 28237978; PMCID: PMC5391226.
      View in: PubMed   Mentions: 24     Fields:    Translation:HumansCells
    330. Coffee consumption is associated with DNA methylation levels of human blood. Eur J Hum Genet. 2017 05; 25(5):608-616. Chuang YH, Quach A, Absher D, Assimes T, Horvath S, Ritz B. PMID: 28198392; PMCID: PMC5437893.
      View in: PubMed   Mentions: 24     Fields:    Translation:HumansCells
    331. Epigenetic clock analysis of diet, exercise, education, and lifestyle factors. Aging (Albany NY). 2017 02 14; 9(2):419-446. Quach A, Levine ME, Tanaka T, Lu AT, Chen BH, Ferrucci L, Ritz B, Bandinelli S, Neuhouser ML, Beasley JM, Snetselaar L, Wallace RB, Tsao PS, Absher D, Assimes TL, Stewart JD, Li Y, Hou L, Baccarelli AA, Whitsel EA, Horvath S. PMID: 28198702; PMCID: PMC5361673.
      View in: PubMed   Mentions: 430     Fields:    Translation:Humans
    332. A Weighted SNP Correlation Network Method for Estimating Polygenic Risk Scores. Methods Mol Biol. 2017; 1613:277-290. Levine ME, Langfelder P, Horvath S. PMID: 28849564; PMCID: PMC5998804.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    333. DNA methylation signatures of chronic low-grade inflammation are associated with complex diseases. Genome Biol. 2016 12 12; 17(1):255. Ligthart S, Marzi C, Aslibekyan S, Mendelson MM, Conneely KN, Tanaka T, Colicino E, Waite LL, Joehanes R, Guan W, Brody JA, Elks C, Marioni R, Jhun MA, Agha G, Bressler J, Ward-Caviness CK, Chen BH, Huan T, Bakulski K, Salfati EL, WHI-EMPC Investigators, Fiorito G, CHARGE epigenetics of Coronary Heart Disease, Wahl S, Schramm K, Sha J, Hernandez DG, Just AC, Smith JA, Sotoodehnia N, Pilling LC, Pankow JS, Tsao PS, Liu C, Zhao W, Guarrera S, Michopoulos VJ, Smith AK, Peters MJ, Melzer D, Vokonas P, Fornage M, Prokisch H, Bis JC, Chu AY, Herder C, Grallert H, Yao C, Shah S, McRae AF, Lin H, Horvath S, Fallin D, Hofman A, Wareham NJ, Wiggins KL, Feinberg AP, Starr JM, Visscher PM, Murabito JM, Kardia SL, Absher DM, Binder EB, Singleton AB, Bandinelli S, Peters A, Waldenberger M, Matullo G, Schwartz JD, Demerath EW, Uitterlinden AG, van Meurs JB, Franco OH, Chen YI, Levy D, Turner ST, Deary IJ, Ressler KJ, Dupuis J, Ferrucci L, Ong KK, Assimes TL, Boerwinkle E, Koenig W, Arnett DK, Baccarelli AA, Benjamin EJ, Dehghan A. PMID: 27955697; PMCID: PMC5151130.
      View in: PubMed   Mentions: 208     Fields:    Translation:HumansCells
    334. Genome-wide changes in lncRNA, splicing, and regional gene expression patterns in autism. Nature. 2016 12 15; 540(7633):423-427. Parikshak NN, Swarup V, Belgard TG, Irimia M, Ramaswami G, Gandal MJ, Hartl C, Leppa V, Ubieta LT, Huang J, Lowe JK, Blencowe BJ, Horvath S, Geschwind DH. PMID: 27919067; PMCID: PMC7102905.
      View in: PubMed   Mentions: 401     Fields:    Translation:HumansAnimalsCells
    335. An epigenetic clock for gestational age at birth based on blood methylation data. Genome Biol. 2016 10 07; 17(1):206. Knight AK, Craig JM, Theda C, Bækvad-Hansen M, Bybjerg-Grauholm J, Hansen CS, Hollegaard MV, Hougaard DM, Mortensen PB, Weinsheimer SM, Werge TM, Brennan PA, Cubells JF, Newport DJ, Stowe ZN, Cheong JL, Dalach P, Doyle LW, Loke YJ, Baccarelli AA, Just AC, Wright RO, Téllez-Rojo MM, Svensson K, Trevisi L, Kennedy EM, Binder EB, Iurato S, Czamara D, Räikkönen K, Lahti JM, Pesonen AK, Kajantie E, Villa PM, Laivuori H, Hämäläinen E, Park HJ, Bailey LB, Parets SE, Kilaru V, Menon R, Horvath S, Bush NR, LeWinn KZ, Tylavsky FA, Conneely KN, Smith AK. PMID: 27717399; PMCID: PMC5054584.
      View in: PubMed   Mentions: 158     Fields:    Translation:HumansCells
    336. DNA methylation-based measures of biological age: meta-analysis predicting time to death. Aging (Albany NY). 2016 09 28; 8(9):1844-1865. Chen BH, Marioni RE, Colicino E, Peters MJ, Ward-Caviness CK, Tsai PC, Roetker NS, Just AC, Demerath EW, Guan W, Bressler J, Fornage M, Studenski S, Vandiver AR, Moore AZ, Tanaka T, Kiel DP, Liang L, Vokonas P, Schwartz J, Lunetta KL, Murabito JM, Bandinelli S, Hernandez DG, Melzer D, Nalls M, Pilling LC, Price TR, Singleton AB, Gieger C, Holle R, Kretschmer A, Kronenberg F, Kunze S, Linseisen J, Meisinger C, Rathmann W, Waldenberger M, Visscher PM, Shah S, Wray NR, McRae AF, Franco OH, Hofman A, Uitterlinden AG, Absher D, Assimes T, Levine ME, Lu AT, Tsao PS, Hou L, Manson JE, Carty CL, LaCroix AZ, Reiner AP, Spector TD, Feinberg AP, Levy D, Baccarelli A, van Meurs J, Bell JT, Peters A, Deary IJ, Pankow JS, Ferrucci L, Horvath S. PMID: 27690265; PMCID: PMC5076441.
      View in: PubMed   Mentions: 621     Fields:    Translation:HumansCells
    337. Specific premature epigenetic aging of cartilage in osteoarthritis. Aging (Albany NY). 2016 09 28; 8(9):2222-2231. Vidal-Bralo L, Lopez-Golan Y, Mera-Varela A, Rego-Perez I, Horvath S, Zhang Y, Del Real Á, Zhai G, Blanco FJ, Riancho JA, Gomez-Reino JJ, Gonzalez A. PMID: 27689435; PMCID: PMC5076459.
      View in: PubMed   Mentions: 24     Fields:    Translation:Humans
    338. Maintenance of age in human neurons generated by microRNA-based neuronal conversion of fibroblasts. Elife. 2016 09 20; 5. Huh CJ, Zhang B, Victor MB, Dahiya S, Batista LF, Horvath S, Yoo AS. PMID: 27644593; PMCID: PMC5067114.
      View in: PubMed   Mentions: 133     Fields:    Translation:HumansCells
    339. An epigenetic clock analysis of race/ethnicity, sex, and coronary heart disease. Genome Biol. 2016 08 11; 17(1):171. Horvath S, Gurven M, Levine ME, Trumble BC, Kaplan H, Allayee H, Ritz BR, Chen B, Lu AT, Rickabaugh TM, Jamieson BD, Sun D, Li S, Chen W, Quintana-Murci L, Fagny M, Kobor MS, Tsao PS, Reiner AP, Edlefsen KL, Absher D, Assimes TL. PMID: 27511193; PMCID: PMC4980791.
      View in: PubMed   Mentions: 444     Fields:    Translation:HumansCells
    340. Epigenetic Aging and Immune Senescence in Women With Insomnia Symptoms: Findings From the Women's Health Initiative Study. Biol Psychiatry. 2017 01 15; 81(2):136-144. Carroll JE, Irwin MR, Levine M, Seeman TE, Absher D, Assimes T, Horvath S. PMID: 27702440; PMCID: PMC5536960.
      View in: PubMed   Mentions: 90     Fields:    Translation:HumansCells
    341. Menopause accelerates biological aging. Proc Natl Acad Sci U S A. 2016 08 16; 113(33):9327-32. Levine ME, Lu AT, Chen BH, Hernandez DG, Singleton AB, Ferrucci L, Bandinelli S, Salfati E, Manson JE, Quach A, Kusters CD, Kuh D, Wong A, Teschendorff AE, Widschwendter M, Ritz BR, Absher D, Assimes TL, Horvath S. PMID: 27457926; PMCID: PMC4995944.
      View in: PubMed   Mentions: 261     Fields:    Translation:Humans
    342. Huntington's disease accelerates epigenetic aging of human brain and disrupts DNA methylation levels. Aging (Albany NY). 2016 07; 8(7):1485-512. Horvath S, Langfelder P, Kwak S, Aaronson J, Rosinski J, Vogt TF, Eszes M, Faull RL, Curtis MA, Waldvogel HJ, Choi OW, Tung S, Vinters HV, Coppola G, Yang XW. PMID: 27479945; PMCID: PMC4993344.
      View in: PubMed   Mentions: 140     Fields:    Translation:HumansCells
    343. Microgeographic Proteomic Networks of the Human Colonic Mucosa and Their Association With Inflammatory Bowel Disease. Cell Mol Gastroenterol Hepatol. 2016 Sep; 2(5):567-583. Li X, LeBlanc J, Elashoff D, McHardy I, Tong M, Roth B, Ippoliti A, Barron G, McGovern D, McDonald K, Newberry R, Graeber T, Horvath S, Goodglick L, Braun J. PMID: 28174738; PMCID: PMC5042708.
      View in: PubMed   Mentions: 25     Fields:    
    344. Epigenetic clock analyses of cellular senescence and ageing. Oncotarget. 2016 Feb 23; 7(8):8524-31. Lowe D, Horvath S, Raj K. PMID: 26885756; PMCID: PMC4890984.
      View in: PubMed   Mentions: 95     Fields:    Translation:HumansCells
    345. Integrated genomics and proteomics define huntingtin CAG length-dependent networks in mice. Nat Neurosci. 2016 Apr; 19(4):623-33. Langfelder P, Cantle JP, Chatzopoulou D, Wang N, Gao F, Al-Ramahi I, Lu XH, Ramos EM, El-Zein K, Zhao Y, Deverasetty S, Tebbe A, Schaab C, Lavery DJ, Howland D, Kwak S, Botas J, Aaronson JS, Rosinski J, Coppola G, Horvath S, Yang XW. PMID: 26900923; PMCID: PMC5984042.
      View in: PubMed   Mentions: 228     Fields:    Translation:Animals
    346. A Systems-Level Analysis of the Peripheral Nerve Intrinsic Axonal Growth Program. Neuron. 2016 Mar 02; 89(5):956-70. Chandran V, Coppola G, Nawabi H, Omura T, Versano R, Huebner EA, Zhang A, Costigan M, Yekkirala A, Barrett L, Blesch A, Michaelevski I, Davis-Turak J, Gao F, Langfelder P, Horvath S, He Z, Benowitz L, Fainzilber M, Tuszynski M, Woolf CJ, Geschwind DH. PMID: 26898779; PMCID: PMC4790095.
      View in: PubMed   Mentions: 208     Fields:    Translation:AnimalsCells
    347. MCT1 Modulates Cancer Cell Pyruvate Export and Growth of Tumors that Co-express MCT1 and MCT4. Cell Rep. 2016 Feb 23; 14(7):1590-1601. Hong CS, Graham NA, Gu W, Espindola Camacho C, Mah V, Maresh EL, Alavi M, Bagryanova L, Krotee PAL, Gardner BK, Behbahan IS, Horvath S, Chia D, Mellinghoff IK, Hurvitz SA, Dubinett SM, Critchlow SE, Kurdistani SK, Goodglick L, Braas D, Graeber TG, Christofk HR. PMID: 26876179; PMCID: PMC4816454.
      View in: PubMed   Mentions: 138     Fields:    Translation:HumansAnimalsCells
    348. Genetic variants near MLST8 and DHX57 affect the epigenetic age of the cerebellum. Nat Commun. 2016 Feb 02; 7:10561. Lu AT, Hannon E, Levine ME, Hao K, Crimmins EM, Lunnon K, Kozlenkov A, Mill J, Dracheva S, Horvath S. PMID: 26830004; PMCID: PMC4740877.
      View in: PubMed   Mentions: 41     Fields:    Translation:HumansCells
    349. Accelerated epigenetic aging in brain is associated with pre-mortem HIV-associated neurocognitive disorders. J Neurovirol. 2016 06; 22(3):366-75. Levine AJ, Quach A, Moore DJ, Achim CL, Soontornniyomkij V, Masliah E, Singer EJ, Gelman B, Nemanim N, Horvath S. PMID: 26689571; PMCID: PMC4900944.
      View in: PubMed   Mentions: 80     Fields:    Translation:HumansCells
    350. Epigenetic age of the pre-frontal cortex is associated with neuritic plaques, amyloid load, and Alzheimer's disease related cognitive functioning. Aging (Albany NY). 2015 Dec; 7(12):1198-211. Levine ME, Lu AT, Bennett DA, Horvath S. PMID: 26684672; PMCID: PMC4712342.
      View in: PubMed   Mentions: 264     Fields:    Translation:Humans
    351. Increased epigenetic age and granulocyte counts in the blood of Parkinson's disease patients. Aging (Albany NY). 2015 Dec; 7(12):1130-42. Horvath S, Ritz BR. PMID: 26655927; PMCID: PMC4712337.
      View in: PubMed   Mentions: 238     Fields:    Translation:HumansCells
    352. Decreased epigenetic age of PBMCs from Italian semi-supercentenarians and their offspring. Aging (Albany NY). 2015 Dec; 7(12):1159-70. Horvath S, Pirazzini C, Bacalini MG, Gentilini D, Di Blasio AM, Delledonne M, Mari D, Arosio B, Monti D, Passarino G, De Rango F, D'Aquila P, Giuliani C, Marasco E, Collino S, Descombes P, Garagnani P, Franceschi C. PMID: 26678252; PMCID: PMC4712339.
      View in: PubMed   Mentions: 167     Fields:    Translation:HumansCells
    353. Prenatal and early life influences on epigenetic age in children: a study of mother-offspring pairs from two cohort studies. Hum Mol Genet. 2016 Jan 01; 25(1):191-201. Simpkin AJ, Hemani G, Suderman M, Gaunt TR, Lyttleton O, Mcardle WL, Ring SM, Sharp GC, Tilling K, Horvath S, Kunze S, Peters A, Waldenberger M, Ward-Caviness C, Nohr EA, Sørensen TI, Relton CL, Smith GD. PMID: 26546615; PMCID: PMC4690495.
      View in: PubMed   Mentions: 121     Fields:    Translation:HumansCells
    354. Transcriptome analyses reveal molecular mechanisms underlying functional recovery after spinal cord injury. Proc Natl Acad Sci U S A. 2015 Oct 27; 112(43):13360-5. Duan H, Ge W, Zhang A, Xi Y, Chen Z, Luo D, Cheng Y, Fan KS, Horvath S, Sofroniew MV, Cheng L, Yang Z, Sun YE, Li X. PMID: 26460053; PMCID: PMC4629389.
      View in: PubMed   Mentions: 66     Fields:    Translation:Animals
    355. DNA methylation age of blood predicts future onset of lung cancer in the women's health initiative. Aging (Albany NY). 2015 Sep; 7(9):690-700. Levine ME, Hosgood HD, Chen B, Absher D, Assimes T, Horvath S. PMID: 26411804; PMCID: PMC4600626.
      View in: PubMed   Mentions: 198     Fields:    Translation:HumansCells
    356. Ribonucleotide reductase subunit M2 predicts survival in subgroups of patients with non-small cell lung carcinoma: effects of gender and smoking status. PLoS One. 2015; 10(5):e0127600. Mah V, Alavi M, Márquez-Garbán DC, Maresh EL, Kim SR, Horvath S, Bagryanova L, Huerta-Yepez S, Chia D, Pietras R, Goodglick L. PMID: 26001082; PMCID: PMC4441434.
      View in: PubMed   Mentions: 23     Fields:    Translation:Humans
    357. Single-cell transcriptome analyses reveal signals to activate dormant neural stem cells. Cell. 2015 May 21; 161(5):1175-1186. Luo Y, Coskun V, Liang A, Yu J, Cheng L, Ge W, Shi Z, Zhang K, Li C, Cui Y, Lin H, Luo D, Wang J, Lin C, Dai Z, Zhu H, Zhang J, Liu J, Liu H, deVellis J, Horvath S, Sun YE, Li S. PMID: 26000486; PMCID: PMC4851109.
      View in: PubMed   Mentions: 152     Fields:    Translation:AnimalsCells
    358. Erratum to: DNA methylation age of human tissues and cell types. Genome Biol. 2015 May 13; 16:96. Horvath S. PMID: 25968125; PMCID: PMC4427927.
      View in: PubMed   Mentions: 106     Fields:    
    359. HIV-1 Infection Accelerates Age According to the Epigenetic Clock. J Infect Dis. 2015 Nov 15; 212(10):1563-73. Horvath S, Levine AJ. PMID: 25969563; PMCID: PMC4621253.
      View in: PubMed   Mentions: 338     Fields:    Translation:HumansCells
    360. The cerebellum ages slowly according to the epigenetic clock. Aging (Albany NY). 2015 May; 7(5):294-306. Horvath S, Mah V, Lu AT, Woo JS, Choi OW, Jasinska AJ, Riancho JA, Tung S, Coles NS, Braun J, Vinters HV, Coles LS. PMID: 26000617; PMCID: PMC4468311.
      View in: PubMed   Mentions: 110     Fields:    Translation:HumansCells
    361. Epigenetic age analysis of children who seem to evade aging. Aging (Albany NY). 2015 May; 7(5):334-9. Walker RF, Liu JS, Peters BA, Ritz BR, Wu T, Ophoff RA, Horvath S. PMID: 25991677; PMCID: PMC4468314.
      View in: PubMed   Mentions: 34     Fields:    Translation:HumansCells
    362. Acceleration of age-associated methylation patterns in HIV-1-infected adults. PLoS One. 2015; 10(3):e0119201. Rickabaugh TM, Baxter RM, Sehl M, Sinsheimer JS, Hultin PM, Hultin LE, Quach A, Martínez-Maza O, Horvath S, Vilain E, Jamieson BD. PMID: 25807146; PMCID: PMC4373843.
      View in: PubMed   Mentions: 78     Fields:    Translation:HumansCells
    363. Accelerated epigenetic aging in Down syndrome. Aging Cell. 2015 Jun; 14(3):491-5. Horvath S, Garagnani P, Bacalini MG, Pirazzini C, Salvioli S, Gentilini D, Di Blasio AM, Giuliani C, Tung S, Vinters HV, Franceschi C. PMID: 25678027; PMCID: PMC4406678.
      View in: PubMed   Mentions: 274     Fields:    Translation:HumansCells
    364. DNA methylation age of blood predicts all-cause mortality in later life. Genome Biol. 2015 Jan 30; 16:25. Marioni RE, Shah S, McRae AF, Chen BH, Colicino E, Harris SE, Gibson J, Henders AK, Redmond P, Cox SR, Pattie A, Corley J, Murphy L, Martin NG, Montgomery GW, Feinberg AP, Fallin MD, Multhaup ML, Jaffe AE, Joehanes R, Schwartz J, Just AC, Lunetta KL, Murabito JM, Starr JM, Horvath S, Baccarelli AA, Levy D, Visscher PM, Wray NR, Deary IJ. PMID: 25633388; PMCID: PMC4350614.
      View in: PubMed   Mentions: 672     Fields:    Translation:HumansCells
    365. The epigenetic clock is correlated with physical and cognitive fitness in the Lothian Birth Cohort 1936. Int J Epidemiol. 2015 Aug; 44(4):1388-96. Marioni RE, Shah S, McRae AF, Ritchie SJ, Muniz-Terrera G, Harris SE, Gibson J, Redmond P, Cox SR, Pattie A, Corley J, Taylor A, Murphy L, Starr JM, Horvath S, Visscher PM, Wray NR, Deary IJ. PMID: 25617346; PMCID: PMC4588858.
      View in: PubMed   Mentions: 349     Fields:    Translation:HumansCells
    366. Identification of schizophrenia-associated loci by combining DNA methylation and gene expression data from whole blood. Eur J Hum Genet. 2015 Aug; 23(8):1106-10. van Eijk KR, de Jong S, Strengman E, Buizer-Voskamp JE, Kahn RS, Boks MP, Horvath S, Ophoff RA. PMID: 25424713; PMCID: PMC4795100.
      View in: PubMed   Mentions: 31     Fields:    Translation:HumansCells
    367. Obesity accelerates epigenetic aging of human liver. Proc Natl Acad Sci U S A. 2014 Oct 28; 111(43):15538-43. Horvath S, Erhart W, Brosch M, Ammerpohl O, von Schönfels W, Ahrens M, Heits N, Bell JT, Tsai PC, Spector TD, Deloukas P, Siebert R, Sipos B, Becker T, Röcken C, Schafmayer C, Hampe J. PMID: 25313081; PMCID: PMC4217403.
      View in: PubMed   Mentions: 430     Fields:    Translation:HumansCells
    368. Alteration in basal and depolarization induced transcriptional network in iPSC derived neurons from Timothy syndrome. Genome Med. 2014; 6(10):75. Tian Y, Voineagu I, Pasca SP, Won H, Chandran V, Horvath S, Dolmetsch RE, Geschwind DH. PMID: 25360157; PMCID: PMC4213483.
      View in: PubMed   Mentions: 50     Fields:    
    369. IL-32 is a molecular marker of a host defense network in human tuberculosis. Sci Transl Med. 2014 Aug 20; 6(250):250ra114. Montoya D, Inkeles MS, Liu PT, Realegeno S, Teles RM, Vaidya P, Munoz MA, Schenk M, Swindell WR, Chun R, Zavala K, Hewison M, Adams JS, Horvath S, Pellegrini M, Bloom BR, Modlin RL. PMID: 25143364; PMCID: PMC4175914.
      View in: PubMed   Mentions: 62     Fields:    Translation:HumansCells
    370. Longitudinal changes of telomere length and epigenetic age related to traumatic stress and post-traumatic stress disorder. Psychoneuroendocrinology. 2015 Jan; 51:506-12. Boks MP, van Mierlo HC, Rutten BP, Radstake TR, De Witte L, Geuze E, Horvath S, Schalkwyk LC, Vinkers CH, Broen JC, Vermetten E. PMID: 25129579.
      View in: PubMed   Mentions: 130     Fields:    Translation:HumansCells
    371. Protein interaction network of alternatively spliced isoforms from brain links genetic risk factors for autism. Nat Commun. 2014 Apr 11; 5:3650. Corominas R, Yang X, Lin GN, Kang S, Shen Y, Ghamsari L, Broly M, Rodriguez M, Tam S, Wanamaker SA, Fan C, Yi S, Tasan M, Lemmens I, Kuang X, Zhao N, Malhotra D, Michaelson JJ, Vacic V, Calderwood MA, Roth FP, Tavernier J, Horvath S, Salehi-Ashtiani K, Korkin D, Sebat J, Hill DE, Hao T, Vidal M, Iakoucheva LM. PMID: 24722188; PMCID: PMC3996537.
      View in: PubMed   Mentions: 80     Fields:    Translation:HumansCells
    372. Genetic, transcriptomic, and epigenetic studies of HIV-associated neurocognitive disorder. J Acquir Immune Defic Syndr. 2014 Apr 01; 65(4):481-503. Levine AJ, Panos SE, Horvath S. PMID: 24583618; PMCID: PMC3947559.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansCells
    373. An epigenetic signature in peripheral blood associated with the haplotype on 17q21.31, a risk factor for neurodegenerative tauopathy. PLoS Genet. 2014 Mar; 10(3):e1004211. Li Y, Chen JA, Sears RL, Gao F, Klein ED, Karydas A, Geschwind MD, Rosen HJ, Boxer AL, Guo W, Pellegrini M, Horvath S, Miller BL, Geschwind DH, Coppola G. PMID: 24603599; PMCID: PMC3945475.
      View in: PubMed   Mentions: 54     Fields:    Translation:HumansCells
    374. Seasonal changes in gene expression represent cell-type composition in whole blood. Hum Mol Genet. 2014 May 15; 23(10):2721-8. De Jong S, Neeleman M, Luykx JJ, ten Berg MJ, Strengman E, Den Breeijen HH, Stijvers LC, Buizer-Voskamp JE, Bakker SC, Kahn RS, Horvath S, Van Solinge WW, Ophoff RA. PMID: 24399446; PMCID: PMC3990170.
      View in: PubMed   Mentions: 24     Fields:    Translation:HumansCells
    375. Integrative functional genomic analyses implicate specific molecular pathways and circuits in autism. Cell. 2013 Nov 21; 155(5):1008-21. Parikshak NN, Luo R, Zhang A, Won H, Lowe JK, Chandran V, Horvath S, Geschwind DH. PMID: 24267887; PMCID: PMC3934107.
      View in: PubMed   Mentions: 639     Fields:    Translation:HumansCells
    376. A modular organization of the human intestinal mucosal microbiota and its association with inflammatory bowel disease. PLoS One. 2013; 8(11):e80702. Tong M, Li X, Wegener Parfrey L, Roth B, Ippoliti A, Wei B, Borneman J, McGovern DP, Frank DN, Li E, Horvath S, Knight R, Braun J. PMID: 24260458; PMCID: PMC3834335.
      View in: PubMed   Mentions: 88     Fields:    Translation:Humans
    377. Transcriptome analysis of HIV-infected peripheral blood monocytes: gene transcripts and networks associated with neurocognitive functioning. J Neuroimmunol. 2013 Dec 15; 265(1-2):96-105. Levine AJ, Horvath S, Miller EN, Singer EJ, Shapshak P, Baldwin GC, Martínez-Maza O, Witt MD, Langfelder P. PMID: 24094461; PMCID: PMC3855455.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansCells
    378. Genetic programs in human and mouse early embryos revealed by single-cell RNA sequencing. Nature. 2013 Aug 29; 500(7464):593-7. Xue Z, Huang K, Cai C, Cai L, Jiang CY, Feng Y, Liu Z, Zeng Q, Cheng L, Sun YE, Liu JY, Horvath S, Fan G. PMID: 23892778; PMCID: PMC4950944.
      View in: PubMed   Mentions: 515     Fields:    Translation:HumansAnimalsCells
    379. Integrative analysis of the microbiome and metabolome of the human intestinal mucosal surface reveals exquisite inter-relationships. Microbiome. 2013 Jun 05; 1(1):17. McHardy IH, Goudarzi M, Tong M, Ruegger PM, Schwager E, Weger JR, Graeber TG, Sonnenburg JL, Horvath S, Huttenhower C, McGovern DP, Fornace AJ, Borneman J, Braun J. PMID: 24450808; PMCID: PMC3971612.
      View in: PubMed   Mentions: 169     Fields:    
    380. Genes and pathways underlying regional and cell type changes in Alzheimer's disease. Genome Med. 2013; 5(5):48. Miller JA, Woltjer RL, Goodenbour JM, Horvath S, Geschwind DH. PMID: 23705665; PMCID: PMC3706780.
      View in: PubMed   Mentions: 165     Fields:    
    381. When is hub gene selection better than standard meta-analysis? PLoS One. 2013; 8(4):e61505. Langfelder P, Mischel PS, Horvath S. PMID: 23613865; PMCID: PMC3629234.
      View in: PubMed   Mentions: 183     Fields:    Translation:HumansAnimals
    382. Cluster and propensity based approximation of a network. BMC Syst Biol. 2013 Mar 14; 7:21. Ranola JM, Langfelder P, Lange K, Horvath S. PMID: 23497424; PMCID: PMC3663730.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimals
    383. Systems analysis of human brain gene expression: mechanisms for HIV-associated neurocognitive impairment and common pathways with Alzheimer's disease. BMC Med Genomics. 2013 Feb 13; 6:4. Levine AJ, Miller JA, Shapshak P, Gelman B, Singer EJ, Hinkin CH, Commins D, Morgello S, Grant I, Horvath S. PMID: 23406646; PMCID: PMC3626801.
      View in: PubMed   Mentions: 47     Fields:    Translation:HumansCells
    384. Prostate cancer cell phenotypes based on AGR2 and CD10 expression. Mod Pathol. 2013 Jun; 26(6):849-59. Ho ME, Quek SI, True LD, Morrissey C, Corey E, Vessella RL, Dumpit R, Nelson PS, Maresh EL, Mah V, Alavi M, Kim SR, Bagryanova L, Horvath S, Chia D, Goodglick L, Liu AY. PMID: 23348903; PMCID: PMC3638070.
      View in: PubMed   Mentions: 22     Fields:    Translation:HumansAnimals
    385. Random generalized linear model: a highly accurate and interpretable ensemble predictor. BMC Bioinformatics. 2013 Jan 16; 14:5. Song L, Langfelder P, Horvath S. PMID: 23323760; PMCID: PMC3645958.
      View in: PubMed   Mentions: 39     Fields:    Translation:HumansAnimals
    386. DNA methylation age of human tissues and cell types. Genome Biol. 2013; 14(10):R115. Horvath S. PMID: 24138928; PMCID: PMC4015143.
      View in: PubMed   Mentions: 3694     Fields:    Translation:HumansAnimalsCells
    387. Comparison of co-expression measures: mutual information, correlation, and model based indices. BMC Bioinformatics. 2012 Dec 09; 13:328. Song L, Langfelder P, Horvath S. PMID: 23217028; PMCID: PMC3586947.
      View in: PubMed   Mentions: 214     Fields:    Translation:Humans
    388. Adipose co-expression networks across Finns and Mexicans identify novel triglyceride-associated genes. BMC Med Genomics. 2012 Dec 06; 5:61. Haas BE, Horvath S, Pietiläinen KH, Cantor RM, Nikkola E, Weissglas-Volkov D, Rissanen A, Civelek M, Cruz-Bautista I, Riba L, Kuusisto J, Kaprio J, Tusie-Luna T, Laakso M, Aguilar-Salinas CA, Pajukanta P. PMID: 23217153; PMCID: PMC3543280.
      View in: PubMed   Mentions: 21     Fields:    Translation:Humans
    389. Genetic analysis of DNA methylation and gene expression levels in whole blood of healthy human subjects. BMC Genomics. 2012 Nov 17; 13:636. van Eijk KR, de Jong S, Boks MP, Langeveld T, Colas F, Veldink JH, de Kovel CG, Janson E, Strengman E, Langfelder P, Kahn RS, van den Berg LH, Horvath S, Ophoff RA. PMID: 23157493; PMCID: PMC3583143.
      View in: PubMed   Mentions: 133     Fields:    Translation:HumansCells
    390. Distinct neurogenomic states in basal ganglia subregions relate differently to singing behavior in songbirds. PLoS Comput Biol. 2012; 8(11):e1002773. Hilliard AT, Miller JE, Horvath S, White SA. PMID: 23144607; PMCID: PMC3493463.
      View in: PubMed   Mentions: 20     Fields:    Translation:Animals
    391. Systems analysis of primary Sjögren's syndrome pathogenesis in salivary glands identifies shared pathways in human and a mouse model. Arthritis Res Ther. 2012 Nov 01; 14(6):R238. Horvath S, Nazmul-Hossain AN, Pollard RP, Kroese FG, Vissink A, Kallenberg CG, Spijkervet FK, Bootsma H, Michie SA, Gorr SU, Peck AB, Cai C, Zhou H, Wong DT. PMID: 23116360; PMCID: PMC3674589.
      View in: PubMed   Mentions: 43     Fields:    Translation:HumansAnimalsCells
    392. Aging effects on DNA methylation modules in human brain and blood tissue. Genome Biol. 2012 Oct 03; 13(10):R97. Horvath S, Zhang Y, Langfelder P, Kahn RS, Boks MP, van Eijk K, van den Berg LH, Ophoff RA. PMID: 23034122; PMCID: PMC4053733.
      View in: PubMed   Mentions: 390     Fields:    Translation:HumansCells
    393. An anatomically comprehensive atlas of the adult human brain transcriptome. Nature. 2012 Sep 20; 489(7416):391-399. Hawrylycz MJ, Lein ES, Guillozet-Bongaarts AL, Shen EH, Ng L, Miller JA, van de Lagemaat LN, Smith KA, Ebbert A, Riley ZL, Abajian C, Beckmann CF, Bernard A, Bertagnolli D, Boe AF, Cartagena PM, Chakravarty MM, Chapin M, Chong J, Dalley RA, David Daly B, Dang C, Datta S, Dee N, Dolbeare TA, Faber V, Feng D, Fowler DR, Goldy J, Gregor BW, Haradon Z, Haynor DR, Hohmann JG, Horvath S, Howard RE, Jeromin A, Jochim JM, Kinnunen M, Lau C, Lazarz ET, Lee C, Lemon TA, Li L, Li Y, Morris JA, Overly CC, Parker PD, Parry SE, Reding M, Royall JJ, Schulkin J, Sequeira PA, Slaughterbeck CR, Smith SC, Sodt AJ, Sunkin SM, Swanson BE, Vawter MP, Williams D, Wohnoutka P, Zielke HR, Geschwind DH, Hof PR, Smith SM, Koch C, Grant SGN, Jones AR. PMID: 22996553; PMCID: PMC4243026.
      View in: PubMed   Mentions: 1671     Fields:    Translation:HumansAnimalsCells
    394. "Good enough solutions" and the genetics of complex diseases. Circ Res. 2012 Aug 03; 111(4):493-504. Weiss JN, Karma A, MacLellan WR, Deng M, Rau CD, Rees CM, Wang J, Wisniewski N, Eskin E, Horvath S, Qu Z, Wang Y, Lusis AJ. PMID: 22859671; PMCID: PMC3428228.
      View in: PubMed   Mentions: 60     Fields:    Translation:HumansAnimals
    395. Network organization of the huntingtin proteomic interactome in mammalian brain. Neuron. 2012 Jul 12; 75(1):41-57. Shirasaki DI, Greiner ER, Al-Ramahi I, Gray M, Boontheung P, Geschwind DH, Botas J, Coppola G, Horvath S, Loo JA, Yang XW. PMID: 22794259; PMCID: PMC3432264.
      View in: PubMed   Mentions: 175     Fields:    Translation:HumansAnimals
    396. Text-mining applied to autoimmune disease research: the Sjögren's syndrome knowledge base. BMC Musculoskelet Disord. 2012 Jul 03; 13:119. Gorr SU, Wennblom TJ, Horvath S, Wong DT, Michie SA. PMID: 22759918; PMCID: PMC3495204.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    397. Network methods for describing sample relationships in genomic datasets: application to Huntington's disease. BMC Syst Biol. 2012 Jun 12; 6:63. Oldham MC, Langfelder P, Horvath S. PMID: 22691535; PMCID: PMC3441531.
      View in: PubMed   Mentions: 89     Fields:    Translation:HumansCells
    398. Mapping of gene expression reveals CYP27A1 as a susceptibility gene for sporadic ALS. PLoS One. 2012; 7(4):e35333. Diekstra FP, Saris CG, van Rheenen W, Franke L, Jansen RC, van Es MA, van Vught PW, Blauw HM, Groen EJ, Horvath S, Estrada K, Rivadeneira F, Hofman A, Uitterlinden AG, Robberecht W, Andersen PM, Melki J, Meininger V, Hardiman O, Landers JE, Brown RH, Shatunov A, Shaw CE, Leigh PN, Al-Chalabi A, Ophoff RA, van den Berg LH, Veldink JH. PMID: 22509407; PMCID: PMC3324559.
      View in: PubMed   Mentions: 32     Fields:    Translation:HumansCells
    399. Differential sensitivity of glioma- versus lung cancer-specific EGFR mutations to EGFR kinase inhibitors. Cancer Discov. 2012 May; 2(5):458-71. Vivanco I, Robins HI, Rohle D, Campos C, Grommes C, Nghiemphu PL, Kubek S, Oldrini B, Chheda MG, Yannuzzi N, Tao H, Zhu S, Iwanami A, Kuga D, Dang J, Pedraza A, Brennan CW, Heguy A, Liau LM, Lieberman F, Yung WK, Gilbert MR, Reardon DA, Drappatz J, Wen PY, Lamborn KR, Chang SM, Prados MD, Fine HA, Horvath S, Wu N, Lassman AB, DeAngelis LM, Yong WH, Kuhn JG, Mischel PS, Mehta MP, Cloughesy TF, Mellinghoff IK. PMID: 22588883; PMCID: PMC3354723.
      View in: PubMed   Mentions: 214     Fields:    Translation:HumansAnimalsCells
    400. Fast R Functions for Robust Correlations and Hierarchical Clustering. J Stat Softw. 2012 Mar; 46(11). Langfelder P, Horvath S. PMID: 23050260; PMCID: PMC3465711.
      View in: PubMed   Mentions: 658  
    401. Resting-state quantitative electroencephalography reveals increased neurophysiologic connectivity in depression. PLoS One. 2012; 7(2):e32508. Leuchter AF, Cook IA, Hunter AM, Cai C, Horvath S. PMID: 22384265; PMCID: PMC3286480.
      View in: PubMed   Mentions: 93     Fields:    Translation:Humans
    402. Molecular microcircuitry underlies functional specification in a basal ganglia circuit dedicated to vocal learning. Neuron. 2012 Feb 09; 73(3):537-52. Hilliard AT, Miller JE, Fraley ER, Horvath S, White SA. PMID: 22325205; PMCID: PMC3278710.
      View in: PubMed   Mentions: 65     Fields:    Translation:HumansAnimals
    403. Strategies for aggregating gene expression data: the collapseRows R function. BMC Bioinformatics. 2011 Aug 04; 12:322. Miller JA, Cai C, Langfelder P, Geschwind DH, Kurian SM, Salomon DR, Horvath S. PMID: 21816037; PMCID: PMC3166942.
      View in: PubMed   Mentions: 190     Fields:    Translation:HumansAnimals
    404. A systems genetic analysis of high density lipoprotein metabolism and network preservation across mouse models. Biochim Biophys Acta. 2012 Mar; 1821(3):435-47. Langfelder P, Castellani LW, Zhou Z, Paul E, Davis R, Schadt EE, Lusis AJ, Horvath S, Mehrabian M. PMID: 21807117; PMCID: PMC3265689.
      View in: PubMed   Mentions: 20     Fields:    Translation:AnimalsCells
    405. Epigenetic predictor of age. PLoS One. 2011; 6(6):e14821. Bocklandt S, Lin W, Sehl ME, Sánchez FJ, Sinsheimer JS, Horvath S, Vilain E. PMID: 21731603; PMCID: PMC3120753.
      View in: PubMed   Mentions: 489     Fields:    Translation:HumansCells
    406. Expression of phosphorylated raf kinase inhibitor protein (pRKIP) is a predictor of lung cancer survival. BMC Cancer. 2011 Jun 21; 11:259. Huerta-Yepez S, Yoon NK, Hernandez-Cueto A, Mah V, Rivera-Pazos CM, Chatterjee D, Vega MI, Maresh EL, Horvath S, Chia D, Bonavida B, Goodglick L. PMID: 21689459; PMCID: PMC3134426.
      View in: PubMed   Mentions: 22     Fields:    Translation:HumansCells
    407. Functional modules distinguish human induced pluripotent stem cells from embryonic stem cells. Stem Cells Dev. 2011 Nov; 20(11):1937-50. Wang A, Huang K, Shen Y, Xue Z, Cai C, Horvath S, Fan G. PMID: 21542696; PMCID: PMC3202894.
      View in: PubMed   Mentions: 21     Fields:    Translation:HumansAnimalsCells
    408. Protein expression based multimarker analysis of breast cancer samples. BMC Cancer. 2011 Jun 08; 11:230. Presson AP, Yoon NK, Bagryanova L, Mah V, Alavi M, Maresh EL, Rajasekaran AK, Goodglick L, Chia D, Horvath S. PMID: 21651811; PMCID: PMC3142534.
      View in: PubMed   Mentions: 26     Fields:    Translation:Humans
    409. Transcriptomic analysis of autistic brain reveals convergent molecular pathology. Nature. 2011 May 25; 474(7351):380-4. Voineagu I, Wang X, Johnston P, Lowe JK, Tian Y, Horvath S, Mill J, Cantor RM, Blencowe BJ, Geschwind DH. PMID: 21614001; PMCID: PMC3607626.
      View in: PubMed   Mentions: 1108     Fields:    Translation:HumansCells
    410. Progesterone and estrogen receptor expression and activity in human non-small cell lung cancer. Steroids. 2011 Aug; 76(9):910-20. Marquez-Garban DC, Mah V, Alavi M, Maresh EL, Chen HW, Bagryanova L, Horvath S, Chia D, Garon E, Goodglick L, Pietras RJ. PMID: 21600232; PMCID: PMC3129425.
      View in: PubMed   Mentions: 43     Fields:    Translation:HumansAnimalsCells
    411. Expression levels of estrogen receptor beta in conjunction with aromatase predict survival in non-small cell lung cancer. Lung Cancer. 2011 Nov; 74(2):318-25. Mah V, Marquez D, Alavi M, Maresh EL, Zhang L, Yoon N, Horvath S, Bagryanova L, Fishbein MC, Chia D, Pietras R, Goodglick L. PMID: 21511357; PMCID: PMC3175023.
      View in: PubMed   Mentions: 36     Fields:    Translation:Humans
    412. Gene networks associated with conditional fear in mice identified using a systems genetics approach. BMC Syst Biol. 2011 Mar 16; 5:43. Park CC, Gale GD, de Jong S, Ghazalpour A, Bennett BJ, Farber CR, Langfelder P, Lin A, Khan AH, Eskin E, Horvath S, Lusis AJ, Ophoff RA, Smith DJ. PMID: 21410935; PMCID: PMC3070648.
      View in: PubMed   Mentions: 61     Fields:    Translation:AnimalsCells
    413. Is my network module preserved and reproducible? PLoS Comput Biol. 2011 Jan 20; 7(1):e1001057. Langfelder P, Luo R, Oldham MC, Horvath S. PMID: 21283776; PMCID: PMC3024255.
      View in: PubMed   Mentions: 603     Fields:    Translation:HumansAnimals
    414. Differential expression of anterior gradient gene AGR2 in prostate cancer. BMC Cancer. 2010 Dec 13; 10:680. Maresh EL, Mah V, Alavi M, Horvath S, Bagryanova L, Liebeskind ES, Knutzen LA, Zhou Y, Chia D, Liu AY, Goodglick L. PMID: 21144054; PMCID: PMC3009682.
      View in: PubMed   Mentions: 34     Fields:    Translation:Humans
    415. Gene coexpression network topology of cardiac development, hypertrophy, and failure. Circ Cardiovasc Genet. 2011 Feb; 4(1):26-35. Dewey FE, Perez MV, Wheeler MT, Watt C, Spin J, Langfelder P, Horvath S, Hannenhalli S, Cappola TP, Ashley EA. PMID: 21127201; PMCID: PMC3324316.
      View in: PubMed   Mentions: 55     Fields:    Translation:HumansAnimalsCells
    416. Higher levels of GATA3 predict better survival in women with breast cancer. Hum Pathol. 2010 Dec; 41(12):1794-801. Yoon NK, Maresh EL, Shen D, Elshimali Y, Apple S, Horvath S, Mah V, Bose S, Chia D, Chang HR, Goodglick L. PMID: 21078439; PMCID: PMC2983489.
      View in: PubMed   Mentions: 81     Fields:    Translation:Humans
    417. Is human blood a good surrogate for brain tissue in transcriptional studies? BMC Genomics. 2010 Oct 20; 11:589. Cai C, Langfelder P, Fuller TF, Oldham MC, Luo R, van den Berg LH, Ophoff RA, Horvath S. PMID: 20961428; PMCID: PMC3091510.
      View in: PubMed   Mentions: 62     Fields:    Translation:HumansCells
    418. Epithelial membrane protein-2 expression is an early predictor of endometrial cancer development. Cancer. 2010 Oct 15; 116(20):4718-26. Habeeb O, Goodglick L, Soslow RA, Rao RG, Gordon LK, Schirripa O, Horvath S, Braun J, Seligson DB, Wadehra M. PMID: 20578181; PMCID: PMC2950887.
      View in: PubMed   Mentions: 26     Fields:    Translation:Humans
    419. Presence of a putative tumor-initiating progenitor cell population predicts poor prognosis in smokers with non-small cell lung cancer. Cancer Res. 2010 Aug 15; 70(16):6639-48. Ooi AT, Mah V, Nickerson DW, Gilbert JL, Ha VL, Hegab AE, Horvath S, Alavi M, Maresh EL, Chia D, Gower AC, Lenburg ME, Spira A, Solis LM, Wistuba II, Walser TC, Wallace WD, Dubinett SM, Goodglick L, Gomperts BN. PMID: 20710044; PMCID: PMC2924777.
      View in: PubMed   Mentions: 38     Fields:    Translation:HumansAnimalsCells
    420. Elevated MED28 expression predicts poor outcome in women with breast cancer. BMC Cancer. 2010 Jun 28; 10:335. Yoon NK, Maresh EL, Elshimali Y, Li A, Horvath S, Seligson DB, Chia D, Goodglick L. PMID: 20584319; PMCID: PMC2907343.
      View in: PubMed   Mentions: 14     Fields:    Translation:Humans
    421. Divergence of human and mouse brain transcriptome highlights Alzheimer disease pathways. Proc Natl Acad Sci U S A. 2010 Jul 13; 107(28):12698-703. Miller JA, Horvath S, Geschwind DH. PMID: 20616000; PMCID: PMC2906579.
      View in: PubMed   Mentions: 277     Fields:    Translation:HumansAnimals
    422. Detecting network modules in fMRI time series: a weighted network analysis approach. Neuroimage. 2010 Oct 01; 52(4):1465-76. Mumford JA, Horvath S, Oldham MC, Langfelder P, Geschwind DH, Poldrack RA. PMID: 20553896; PMCID: PMC3632300.
      View in: PubMed   Mentions: 42     Fields:    Translation:Humans
    423. Global analysis of gene activity during Arabidopsis seed development and identification of seed-specific transcription factors. Proc Natl Acad Sci U S A. 2010 May 04; 107(18):8063-70. Le BH, Cheng C, Bui AQ, Wagmaister JA, Henry KF, Pelletier J, Kwong L, Belmonte M, Kirkbride R, Horvath S, Drews GN, Fischer RL, Okamuro JK, Harada JJ, Goldberg RB. PMID: 20385809; PMCID: PMC2889569.
      View in: PubMed   Mentions: 309     Fields:    Translation:Animals
    424. EGFR signaling through an Akt-SREBP-1-dependent, rapamycin-resistant pathway sensitizes glioblastomas to antilipogenic therapy. Sci Signal. 2009 Dec 15; 2(101):ra82. Guo D, Prins RM, Dang J, Kuga D, Iwanami A, Soto H, Lin KY, Huang TT, Akhavan D, Hock MB, Zhu S, Kofman AA, Bensinger SJ, Yong WH, Vinters HV, Horvath S, Watson AD, Kuhn JG, Robins HI, Mehta MP, Wen PY, DeAngelis LM, Prados MD, Mellinghoff IK, Cloughesy TF, Mischel PS. PMID: 20009104; PMCID: PMC2978002.
      View in: PubMed   Mentions: 222     Fields:    Translation:HumansCells
    425. A systems genetics approach implicates USF1, FADS3, and other causal candidate genes for familial combined hyperlipidemia. PLoS Genet. 2009 Sep; 5(9):e1000642. Plaisier CL, Horvath S, Huertas-Vazquez A, Cruz-Bautista I, Herrera MF, Tusie-Luna T, Aguilar-Salinas C, Pajukanta P. PMID: 19750004; PMCID: PMC2730565.
      View in: PubMed   Mentions: 94     Fields:    Translation:HumansCells
    426. Weighted gene co-expression network analysis of the peripheral blood from Amyotrophic Lateral Sclerosis patients. BMC Genomics. 2009 Aug 27; 10:405. Saris CG, Horvath S, van Vught PW, van Es MA, Blauw HM, Fuller TF, Langfelder P, DeYoung J, Wokke JH, Veldink JH, van den Berg LH, Ophoff RA. PMID: 19712483; PMCID: PMC2743717.
      View in: PubMed   Mentions: 107     Fields:    Translation:Humans
    427. The organization of the transcriptional network in specific neuronal classes. Mol Syst Biol. 2009; 5:291. Winden KD, Oldham MC, Mirnics K, Ebert PJ, Swan CH, Levitt P, Rubenstein JL, Horvath S, Geschwind DH. PMID: 19638972; PMCID: PMC2724976.
      View in: PubMed   Mentions: 80     Fields:    Translation:AnimalsCells
    428. Network module detection: Affinity search technique with the multi-node topological overlap measure. BMC Res Notes. 2009 Jul 20; 2:142. Li A, Horvath S. PMID: 19619323; PMCID: PMC2727520.
      View in: PubMed   Mentions: 34     Fields:    
    429. Signed weighted gene co-expression network analysis of transcriptional regulation in murine embryonic stem cells. BMC Genomics. 2009 Jul 20; 10:327. Mason MJ, Fan G, Plath K, Zhou Q, Horvath S. PMID: 19619308; PMCID: PMC2727539.
      View in: PubMed   Mentions: 136     Fields:    Translation:AnimalsCells
    430. Biomarkers for early and late stage chronic allograft nephropathy by proteogenomic profiling of peripheral blood. PLoS One. 2009 Jul 10; 4(7):e6212. Kurian SM, Heilman R, Mondala TS, Nakorchevsky A, Hewel JA, Campbell D, Robison EH, Wang L, Lin W, Gaber L, Solez K, Shidban H, Mendez R, Schaffer RL, Fisher JS, Flechner SM, Head SR, Horvath S, Yates JR, Marsh CL, Salomon DR. PMID: 19593431; PMCID: PMC2703807.
      View in: PubMed   Mentions: 36     Fields:    Translation:Humans
    431. Weighted gene co-expression network analysis identifies biomarkers in glycerol kinase deficient mice. Mol Genet Metab. 2009 Sep-Oct; 98(1-2):203-14. MacLennan NK, Dong J, Aten JE, Horvath S, Rahib L, Ornelas L, Dipple KM, McCabe ER. PMID: 19546021.
      View in: PubMed   Mentions: 20     Fields:    Translation:AnimalsCells
    432. Global levels of histone modifications predict prognosis in different cancers. Am J Pathol. 2009 May; 174(5):1619-28. Seligson DB, Horvath S, McBrian MA, Mah V, Yu H, Tze S, Wang Q, Chia D, Goodglick L, Kurdistani SK. PMID: 19349354; PMCID: PMC2671251.
      View in: PubMed   Mentions: 227     Fields:    Translation:HumansCells
    433. Neurosphere formation is an independent predictor of clinical outcome in malignant glioma. Stem Cells. 2009 Apr; 27(4):980-7. Laks DR, Masterman-Smith M, Visnyei K, Angenieux B, Orozco NM, Foran I, Yong WH, Vinters HV, Liau LM, Lazareff JA, Mischel PS, Cloughesy TF, Horvath S, Kornblum HI. PMID: 19353526; PMCID: PMC3177534.
      View in: PubMed   Mentions: 124     Fields:    Translation:HumansAnimalsCells
    434. Genetic dissection of a major mouse obesity QTL (Carfhg2): integration of gene expression and causality modeling. Physiol Genomics. 2009 May 13; 37(3):294-302. Farber CR, Aten JE, Farber EA, de Vera V, Gularte R, Islas-Trejo A, Wen P, Horvath S, Lucero M, Lusis AJ, Medrano JF. PMID: 19336533; PMCID: PMC2685499.
      View in: PubMed   Mentions: 17     Fields:    Translation:AnimalsCells
    435. Role of the murine reprogramming factors in the induction of pluripotency. Cell. 2009 Jan 23; 136(2):364-77. Sridharan R, Tchieu J, Mason MJ, Yachechko R, Kuoy E, Horvath S, Zhou Q, Plath K. PMID: 19167336; PMCID: PMC3273494.
      View in: PubMed   Mentions: 371     Fields:    Translation:AnimalsCells
    436. Systems biology analysis of Sjögren's syndrome and mucosa-associated lymphoid tissue lymphoma in parotid glands. Arthritis Rheum. 2009 Jan; 60(1):81-92. Hu S, Zhou M, Jiang J, Wang J, Elashoff D, Gorr S, Michie SA, Spijkervet FK, Bootsma H, Kallenberg CG, Vissink A, Horvath S, Wong DT. PMID: 19116902; PMCID: PMC2718690.
      View in: PubMed   Mentions: 23     Fields:    Translation:Humans
    437. Higher expression levels of 14-3-3sigma in ductal carcinoma in situ of the breast predict poorer outcome. Cancer Biomark. 2009; 5(4):215-24. Yoon NK, Seligson DB, Chia D, Elshimali Y, Sulur G, Li A, Horvath S, Maresh E, Mah V, Bose S, Bonavida B, Goodglick L. PMID: 19729831; PMCID: PMC3170666.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    438. An integrative genetics approach to identify candidate genes regulating BMD: combining linkage, gene expression, and association. J Bone Miner Res. 2009 Jan; 24(1):105-16. Farber CR, van Nas A, Ghazalpour A, Aten JE, Doss S, Sos B, Schadt EE, Ingram-Drake L, Davis RC, Horvath S, Smith DJ, Drake TA, Lusis AJ. PMID: 18767929; PMCID: PMC2661539.
      View in: PubMed   Mentions: 36     Fields:    Translation:Animals
    439. WGCNA: an R package for weighted correlation network analysis. BMC Bioinformatics. 2008 Dec 29; 9:559. Langfelder P, Horvath S. PMID: 19114008; PMCID: PMC2631488.
      View in: PubMed   Mentions: 14292     Fields:    Translation:HumansAnimals
    440. Integrated weighted gene co-expression network analysis with an application to chronic fatigue syndrome. BMC Syst Biol. 2008 Nov 06; 2:95. Presson AP, Sobel EM, Papp JC, Suarez CJ, Whistler T, Rajeevan MS, Vernon SD, Horvath S. PMID: 18986552; PMCID: PMC2625353.
      View in: PubMed   Mentions: 104     Fields:    Translation:Humans
    441. Elucidating the role of gonadal hormones in sexually dimorphic gene coexpression networks. Endocrinology. 2009 Mar; 150(3):1235-49. van Nas A, Guhathakurta D, Wang SS, Yehya N, Horvath S, Zhang B, Ingram-Drake L, Chaudhuri G, Schadt EE, Drake TA, Arnold AP, Lusis AJ. PMID: 18974276; PMCID: PMC2654741.
      View in: PubMed   Mentions: 138     Fields:    Translation:Animals
    442. Gene expression analysis of glioblastomas identifies the major molecular basis for the prognostic benefit of younger age. BMC Med Genomics. 2008 Oct 21; 1:52. Lee Y, Scheck AC, Cloughesy TF, Lai A, Dong J, Farooqi HK, Liau LM, Horvath S, Mischel PS, Nelson SF. PMID: 18940004; PMCID: PMC2596165.
      View in: PubMed   Mentions: 135     Fields:    
    443. Functional organization of the transcriptome in human brain. Nat Neurosci. 2008 Nov; 11(11):1271-82. Oldham MC, Konopka G, Iwamoto K, Langfelder P, Kato T, Horvath S, Geschwind DH. PMID: 18849986; PMCID: PMC2756411.
      View in: PubMed   Mentions: 457     Fields:    Translation:HumansCells
    444. Geometric interpretation of gene coexpression network analysis. PLoS Comput Biol. 2008 Aug 15; 4(8):e1000117. Horvath S, Dong J. PMID: 18704157; PMCID: PMC2446438.
      View in: PubMed   Mentions: 475     Fields:    Translation:HumansAnimals
    445. Using genetic markers to orient the edges in quantitative trait networks: the NEO software. BMC Syst Biol. 2008 Apr 15; 2:34. Aten JE, Fuller TF, Lusis AJ, Horvath S. PMID: 18412962; PMCID: PMC2387136.
      View in: PubMed   Mentions: 88     Fields:    
    446. Variations in DNA elucidate molecular networks that cause disease. Nature. 2008 Mar 27; 452(7186):429-35. Chen Y, Zhu J, Lum PY, Yang X, Pinto S, MacNeil DJ, Zhang C, Lamb J, Edwards S, Sieberts SK, Leonardson A, Castellini LW, Wang S, Champy MF, Zhang B, Emilsson V, Doss S, Ghazalpour A, Horvath S, Drake TA, Lusis AJ, Schadt EE. PMID: 18344982; PMCID: PMC2841398.
      View in: PubMed   Mentions: 515     Fields:    Translation:AnimalsCells
    447. Antitumor activity of rapamycin in a Phase I trial for patients with recurrent PTEN-deficient glioblastoma. PLoS Med. 2008 Jan 22; 5(1):e8. Cloughesy TF, Yoshimoto K, Nghiemphu P, Brown K, Dang J, Zhu S, Hsueh T, Chen Y, Wang W, Youngkin D, Liau L, Martin N, Becker D, Bergsneider M, Lai A, Green R, Oglesby T, Koleto M, Trent J, Horvath S, Mischel PS, Mellinghoff IK, Sawyers CL. PMID: 18215105; PMCID: PMC2211560.
      View in: PubMed   Mentions: 315     Fields:    Translation:HumansCellsCTClinical Trials
    448. Development of a real-time RT-PCR assay for detecting EGFRvIII in glioblastoma samples. Clin Cancer Res. 2008 Jan 15; 14(2):488-93. Yoshimoto K, Dang J, Zhu S, Nathanson D, Huang T, Dumont R, Seligson DB, Yong WH, Xiong Z, Rao N, Winther H, Chakravarti A, Bigner DD, Mellinghoff IK, Horvath S, Cavenee WK, Cloughesy TF, Mischel PS. PMID: 18223223.
      View in: PubMed   Mentions: 59     Fields:    Translation:Humans
    449. Maternal embryonic leucine zipper kinase is a key regulator of the proliferation of malignant brain tumors, including brain tumor stem cells. J Neurosci Res. 2008 Jan; 86(1):48-60. Nakano I, Masterman-Smith M, Saigusa K, Paucar AA, Horvath S, Shoemaker L, Watanabe M, Negro A, Bajpai R, Howes A, Lelievre V, Waschek JA, Lazareff JA, Freije WA, Liau LM, Gilbertson RJ, Cloughesy TF, Geschwind DH, Nelson SF, Mischel PS, Terskikh AV, Kornblum HI. PMID: 17722061.
      View in: PubMed   Mentions: 95     Fields:    Translation:HumansAnimalsCells
    450. Eigengene networks for studying the relationships between co-expression modules. BMC Syst Biol. 2007 Nov 21; 1:54. Langfelder P, Horvath S. PMID: 18031580; PMCID: PMC2267703.
      View in: PubMed   Mentions: 505     Fields:    Translation:HumansAnimals
    451. Na,K-adenosine triphosphatase alpha1-subunit predicts survival of renal clear cell carcinoma. J Urol. 2008 Jan; 179(1):338-45. Seligson DB, Rajasekaran SA, Yu H, Liu X, Eeva M, Tze S, Ball W, Horvath S, deKernion JB, Rajasekaran AK. PMID: 18006011.
      View in: PubMed   Mentions: 21     Fields:    Translation:Humans
    452. Defining clusters from a hierarchical cluster tree: the Dynamic Tree Cut package for R. Bioinformatics. 2008 Mar 01; 24(5):719-20. Langfelder P, Zhang B, Horvath S. PMID: 18024473.
      View in: PubMed   Mentions: 1044     Fields:    Translation:Cells
    453. Expression of X-linked inhibitor of apoptosis protein is a strong predictor of human prostate cancer recurrence. Clin Cancer Res. 2007 Oct 15; 13(20):6056-63. Seligson DB, Hongo F, Huerta-Yepez S, Mizutani Y, Miki T, Yu H, Horvath S, Chia D, Goodglick L, Bonavida B. PMID: 17947468.
      View in: PubMed   Mentions: 43     Fields:    Translation:Humans
    454. Breast cancer molecular signatures as determined by SAGE: correlation with lymph node status. Mol Cancer Res. 2007 Sep; 5(9):881-90. Abba MC, Sun H, Hawkins KA, Drake JA, Hu Y, Nunez MI, Gaddis S, Shi T, Horvath S, Sahin A, Aldaz CM. PMID: 17855657; PMCID: PMC4186709.
      View in: PubMed   Mentions: 65     Fields:    Translation:HumansCells
    455. Weighted gene coexpression network analysis strategies applied to mouse weight. Mamm Genome. 2007 Jul; 18(6-7):463-72. Fuller TF, Ghazalpour A, Aten JE, Drake TA, Lusis AJ, Horvath S. PMID: 17668265; PMCID: PMC1998880.
      View in: PubMed   Mentions: 205     Fields:    Translation:AnimalsCells
    456. Understanding network concepts in modules. BMC Syst Biol. 2007 Jun 04; 1:24. Dong J, Horvath S. PMID: 17547772; PMCID: PMC3238286.
      View in: PubMed   Mentions: 204     Fields:    Translation:Animals
    457. Relationship between survival and edema in malignant gliomas: role of vascular endothelial growth factor and neuronal pentraxin 2. Clin Cancer Res. 2007 May 01; 13(9):2592-8. Carlson MR, Pope WB, Horvath S, Braunstein JG, Nghiemphu P, Tso CL, Mellinghoff I, Lai A, Liau LM, Mischel PS, Dong J, Nelson SF, Cloughesy TF. PMID: 17473188.
      View in: PubMed   Mentions: 64     Fields:    Translation:Humans
    458. Glycerol kinase deficiency alters expression of genes involved in lipid metabolism, carbohydrate metabolism, and insulin signaling. Eur J Hum Genet. 2007 Jun; 15(6):646-57. Rahib L, MacLennan NK, Horvath S, Liao JC, Dipple KM. PMID: 17406644.
      View in: PubMed   Mentions: 33     Fields:    Translation:AnimalsCells
    459. Air-pollutant chemicals and oxidized lipids exhibit genome-wide synergistic effects on endothelial cells. Genome Biol. 2007; 8(7):R149. Gong KW, Zhao W, Li N, Barajas B, Kleinman M, Sioutas C, Horvath S, Lusis AJ, Nel A, Araujo JA. PMID: 17655762; PMCID: PMC2323217.
      View in: PubMed   Mentions: 51     Fields:    Translation:HumansCells
    460. Network neighborhood analysis with the multi-node topological overlap measure. Bioinformatics. 2007 Jan 15; 23(2):222-31. Li A, Horvath S. PMID: 17110366.
      View in: PubMed   Mentions: 105     Fields:    Translation:HumansCells
    461. Conservation and evolution of gene coexpression networks in human and chimpanzee brains. Proc Natl Acad Sci U S A. 2006 Nov 21; 103(47):17973-8. Oldham MC, Horvath S, Geschwind DH. PMID: 17101986; PMCID: PMC1693857.
      View in: PubMed   Mentions: 334     Fields:    Translation:HumansAnimals
    462. Analysis of oncogenic signaling networks in glioblastoma identifies ASPM as a molecular target. Proc Natl Acad Sci U S A. 2006 Nov 14; 103(46):17402-7. Horvath S, Zhang B, Carlson M, Lu KV, Zhu S, Felciano RM, Laurance MF, Zhao W, Qi S, Chen Z, Lee Y, Scheck AC, Liau LM, Wu H, Geschwind DH, Febbo PG, Kornblum HI, Cloughesy TF, Nelson SF, Mischel PS. PMID: 17090670; PMCID: PMC1635024.
      View in: PubMed   Mentions: 364     Fields:    Translation:HumansAnimalsCells
    463. Repetitive sequence environment distinguishes housekeeping genes. Gene. 2007 Apr 01; 390(1-2):153-65. Eller CD, Regelson M, Merriman B, Nelson S, Horvath S, Marahrens Y. PMID: 17141428; PMCID: PMC1857324.
      View in: PubMed   Mentions: 27     Fields:    Translation:HumansCells
    464. Identification of inflammatory gene modules based on variations of human endothelial cell responses to oxidized lipids. Proc Natl Acad Sci U S A. 2006 Aug 22; 103(34):12741-6. Gargalovic PS, Imura M, Zhang B, Gharavi NM, Clark MJ, Pagnon J, Yang WP, He A, Truong A, Patel S, Nelson SF, Horvath S, Berliner JA, Kirchgessner TG, Lusis AJ. PMID: 16912112; PMCID: PMC1568918.
      View in: PubMed   Mentions: 182     Fields:    Translation:HumansCells
    465. Flap endonuclease 1 is overexpressed in prostate cancer and is associated with a high Gleason score. BJU Int. 2006 Aug; 98(2):445-51. Lam JS, Seligson DB, Yu H, Li A, Eeva M, Pantuck AJ, Zeng G, Horvath S, Belldegrun AS. PMID: 16879693.
      View in: PubMed   Mentions: 44     Fields:    Translation:Humans
    466. Integrating genetic and network analysis to characterize genes related to mouse weight. PLoS Genet. 2006 Aug 18; 2(8):e130. Ghazalpour A, Doss S, Zhang B, Wang S, Plaisier C, Castellanos R, Brozell A, Schadt EE, Drake TA, Lusis AJ, Horvath S. PMID: 16934000; PMCID: PMC1550283.
      View in: PubMed   Mentions: 259     Fields:    Translation:Animals
    467. Gene connectivity, function, and sequence conservation: predictions from modular yeast co-expression networks. BMC Genomics. 2006 Mar 03; 7:40. Carlson MR, Zhang B, Fang Z, Mischel PS, Horvath S, Nelson SF. PMID: 16515682; PMCID: PMC1413526.
      View in: PubMed   Mentions: 191     Fields:    Translation:AnimalsCells
    468. Extreme skewing of X chromosome inactivation in mothers of homosexual men. Hum Genet. 2006 Feb; 118(6):691-4. Bocklandt S, Horvath S, Vilain E, Hamer DH. PMID: 16369763.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansCells
    469. Distinct gene expression profiles in adult mouse heart following targeted MAP kinase activation. Physiol Genomics. 2006 Mar 13; 25(1):50-9. Mitchell S, Ota A, Foster W, Zhang B, Fang Z, Patel S, Nelson SF, Horvath S, Wang Y. PMID: 16368875.
      View in: PubMed   Mentions: 21     Fields:    Translation:Animals
    470. Targeted disruption of glycerol kinase gene in mice: expression analysis in liver shows alterations in network partners related to glycerol kinase activity. Hum Mol Genet. 2006 Feb 01; 15(3):405-15. MacLennan NK, Rahib L, Shin C, Fang Z, Horvath S, Dean J, Liao JC, McCabe ER, Dipple KM. PMID: 16368706.
      View in: PubMed   Mentions: 20     Fields:    Translation:Animals
    471. Molecular determinants of the response of glioblastomas to EGFR kinase inhibitors. N Engl J Med. 2005 Nov 10; 353(19):2012-24. Mellinghoff IK, Wang MY, Vivanco I, Haas-Kogan DA, Zhu S, Dia EQ, Lu KV, Yoshimoto K, Huang JH, Chute DJ, Riggs BL, Horvath S, Liau LM, Cavenee WK, Rao PN, Beroukhim R, Peck TC, Lee JC, Sellers WR, Stokoe D, Prados M, Cloughesy TF, Sawyers CL, Mischel PS. PMID: 16282176.
      View in: PubMed   Mentions: 623     Fields:    Translation:HumansCells
    472. Inhibition of Atm and/or Atr disrupts gene silencing on the inactive X chromosome. Biochem Biophys Res Commun. 2005 Nov 25; 337(3):875-80. Ouyang Y, Salstrom J, Diaz-Perez S, Nahas S, Matsuno Y, Dawson D, Teitell MA, Horvath S, Riggs AD, Gatti RA, Marahrens Y. PMID: 16213462.
      View in: PubMed   Mentions: 5     Fields:    Translation:AnimalsCells
    473. A general framework for weighted gene co-expression network analysis. Stat Appl Genet Mol Biol. 2005; 4:Article17. Zhang B, Horvath S. PMID: 16646834.
      View in: PubMed   Mentions: 3035     Fields:    
    474. Expression of transcription factor Yin Yang 1 in prostate cancer. Int J Oncol. 2005 Jul; 27(1):131-41. Seligson D, Horvath S, Huerta-Yepez S, Hanna S, Garban H, Roberts A, Shi T, Liu X, Chia D, Goodglick L, Bonavida B. PMID: 15942652.
      View in: PubMed   Mentions: 75     Fields:    Translation:HumansCells
    475. Global histone modification patterns predict risk of prostate cancer recurrence. Nature. 2005 Jun 30; 435(7046):1262-6. Seligson DB, Horvath S, Shi T, Yu H, Tze S, Grunstein M, Kurdistani SK. PMID: 15988529.
      View in: PubMed   Mentions: 452     Fields:    Translation:HumansCells
    476. Clinicopathologic and molecular correlations of necrosis in the primary tumor of patients with renal cell carcinoma. Cancer. 2005 Jun 15; 103(12):2517-25. Lam JS, Shvarts O, Said JW, Pantuck AJ, Seligson DB, Aldridge ME, Bui MH, Liu X, Horvath S, Figlin RA, Belldegrun AS. PMID: 15880379.
      View in: PubMed   Mentions: 48     Fields:    Translation:Humans
    477. Using tumor markers to predict the survival of patients with metastatic renal cell carcinoma. J Urol. 2005 May; 173(5):1496-501. Kim HL, Seligson D, Liu X, Janzen N, Bui MH, Yu H, Shi T, Belldegrun AS, Horvath S, Figlin RA. PMID: 15821467.
      View in: PubMed   Mentions: 64     Fields:    Translation:Humans
    478. Tumor classification by tissue microarray profiling: random forest clustering applied to renal cell carcinoma. Mod Pathol. 2005 Apr; 18(4):547-57. Shi T, Seligson D, Belldegrun AS, Palotie A, Horvath S. PMID: 15529185.
      View in: PubMed   Mentions: 48     Fields:    Translation:Humans
    479. Prostate stem cell antigen is overexpressed in prostate cancer metastases. Clin Cancer Res. 2005 Apr 01; 11(7):2591-6. Lam JS, Yamashiro J, Shintaku IP, Vessella RL, Jenkins RB, Horvath S, Said JW, Reiter RE. PMID: 15814638.
      View in: PubMed   Mentions: 60     Fields:    Translation:Humans
    480. p53 is an independent predictor of tumor recurrence and progression after nephrectomy in patients with localized renal cell carcinoma. J Urol. 2005 Mar; 173(3):725-8. Shvarts O, Seligson D, Lam J, Shi T, Horvath S, Figlin R, Belldegrun A, Pantuck AJ. PMID: 15711252.
      View in: PubMed   Mentions: 25     Fields:    Translation:Humans
    481. Ridge regression based hybrid genetic algorithms for multi-locus quantitative trait mapping. Int J Bioinform Res Appl. 2005; 1(3):261-72. Zhang B, Horvath S. PMID: 18048135.
      View in: PubMed   Mentions: 9     Fields:    Translation:Animals
    482. Antibody-based profiling of the phosphoinositide 3-kinase pathway in clinical prostate cancer. Clin Cancer Res. 2004 Dec 15; 10(24):8351-6. Thomas GV, Horvath S, Smith BL, Crosby K, Lebel LA, Schrage M, Said J, De Kernion J, Reiter RE, Sawyers CL. PMID: 15623612.
      View in: PubMed   Mentions: 22     Fields:    Translation:HumansCells
    483. Trefoil factor 3 is overexpressed in human prostate cancer. Prostate. 2004 Nov 01; 61(3):209-14. Garraway IP, Seligson D, Said J, Horvath S, Reiter RE. PMID: 15368472.
      View in: PubMed   Mentions: 30     Fields:    Translation:Humans
    484. Gene expression profiling of gliomas strongly predicts survival. Cancer Res. 2004 Sep 15; 64(18):6503-10. Freije WA, Castro-Vargas FE, Fang Z, Horvath S, Cloughesy T, Liau LM, Mischel PS, Nelson SF. PMID: 15374961.
      View in: PubMed   Mentions: 363     Fields:    Translation:Humans
    485. Using protein expressions to predict survival in clear cell renal carcinoma. Clin Cancer Res. 2004 Aug 15; 10(16):5464-71. Kim HL, Seligson D, Liu X, Janzen N, Bui MH, Yu H, Shi T, Figlin RA, Horvath S, Belldegrun AS. PMID: 15328185.
      View in: PubMed   Mentions: 69     Fields:    Translation:Humans
    486. Statistical methods for analyzing tissue microarray data. J Biopharm Stat. 2004 Aug; 14(3):671-85. Liu X, Minin V, Huang Y, Seligson DB, Horvath S. PMID: 15468758.
      View in: PubMed   Mentions: 24     Fields:    Translation:Humans
    487. Prostate stem cell antigen expression is associated with gleason score, seminal vesicle invasion and capsular invasion in prostate cancer. J Urol. 2004 Mar; 171(3):1117-21. Han KR, Seligson DB, Liu X, Horvath S, Shintaku PI, Thomas GV, Said JW, Reiter RE. PMID: 14767283.
      View in: PubMed   Mentions: 44     Fields:    Translation:Humans
    488. Family-based tests for associating haplotypes with general phenotype data: application to asthma genetics. Genet Epidemiol. 2004 Jan; 26(1):61-9. Horvath S, Xu X, Lake SL, Silverman EK, Weiss ST, Laird NM. PMID: 14691957.
      View in: PubMed   Mentions: 173     Fields:    Translation:Humans
    489. Finding the best ridge regression subset by genetic algorithms: applications to multilocus quantitative trait mapping. Conf Proc IEEE Eng Med Biol Soc. 2004; 2004:2793-6. Zhang B, Horvath S. PMID: 17270857.
      View in: PubMed   Mentions: 1     Fields:    
    490. Multivariate variance-components analysis of longitudinal blood pressure measurements from the Framingham Heart Study. BMC Genet. 2003 Dec 31; 4 Suppl 1:S55. Kraft P, Bauman L, Yuan JY, Horvath S, Framingham Heart Study. PMID: 14975123; PMCID: PMC1866492.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansCells
    491. Sexually dimorphic gene expression in mouse brain precedes gonadal differentiation. Brain Res Mol Brain Res. 2003 Oct 21; 118(1-2):82-90. Dewing P, Shi T, Horvath S, Vilain E. PMID: 14559357.
      View in: PubMed   Mentions: 120     Fields:    Translation:Animals
    492. The genetics of gene expression and gene mapping. Trends Biotechnol. 2003 Sep; 21(9):377-8. Kraft P, Horvath S. PMID: 12948667.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimalsCells
    493. High concentrations of long interspersed nuclear element sequence distinguish monoallelically expressed genes. Proc Natl Acad Sci U S A. 2003 Aug 19; 100(17):9940-5. Allen E, Horvath S, Tong F, Kraft P, Spiteri E, Riggs AD, Marahrens Y. PMID: 12909712; PMCID: PMC187893.
      View in: PubMed   Mentions: 57     Fields:    Translation:HumansAnimalsCells
    494. Gene expression profiling identifies molecular subtypes of gliomas. Oncogene. 2003 Jul 31; 22(31):4918-23. Shai R, Shi T, Kremen TJ, Horvath S, Liau LM, Cloughesy TF, Mischel PS, Nelson SF. PMID: 12894235.
      View in: PubMed   Mentions: 140     Fields:    Translation:Humans
    495. Analysis of the phosphatidylinositol 3'-kinase signaling pathway in glioblastoma patients in vivo. Cancer Res. 2003 Jun 01; 63(11):2742-6. Choe G, Horvath S, Cloughesy TF, Crosby K, Seligson D, Palotie A, Inge L, Smith BL, Sawyers CL, Mischel PS. PMID: 12782577.
      View in: PubMed   Mentions: 173     Fields:    Translation:HumansCells
    496. Identification of molecular subtypes of glioblastoma by gene expression profiling. Oncogene. 2003 Apr 17; 22(15):2361-73. Mischel PS, Shai R, Shi T, Horvath S, Lu KV, Choe G, Seligson D, Kremen TJ, Palotie A, Liau LM, Cloughesy TF, Nelson SF. PMID: 12700671.
      View in: PubMed   Mentions: 102     Fields:    Translation:HumansCells
    497. Analysis of the Na,K-ATPase alpha- and beta-subunit expression profiles of bladder cancer using tissue microarrays. Cancer. 2003 Apr 15; 97(8):1859-68. Espineda C, Seligson DB, James Ball W, Rao J, Palotie A, Horvath S, Huang Y, Shi T, Rajasekaran AK. PMID: 12673711.
      View in: PubMed   Mentions: 37     Fields:    Translation:Humans
    498. A family-based test for correlation between gene expression and trait values. Am J Hum Genet. 2003 May; 72(5):1323-30. Kraft P, Schadt E, Aten J, Horvath S. PMID: 12687497; PMCID: PMC1180286.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansCells
    499. Correlation of Ki-67 and gelsolin expression to clinical outcome in renal clear cell carcinoma. Urology. 2003 Apr; 61(4):845-50. Visapää H, Bui M, Huang Y, Seligson D, Tsai H, Pantuck A, Figlin R, Rao JY, Belldegrun A, Horvath S, Palotie A. PMID: 12670587.
      View in: PubMed   Mentions: 34     Fields:    Translation:Humans
    500. Loss of CD10 (neutral endopeptidase) is a frequent and early event in human prostate cancer. Prostate. 2003 Apr 01; 55(1):71-80. Freedland SJ, Seligson DB, Liu AY, Pantuck AJ, Paik SH, Horvath S, Wieder JA, Zisman A, Nguyen D, Tso CL, Palotie AV, Belldegrun AS. PMID: 12640663.
      View in: PubMed   Mentions: 27     Fields:    Translation:HumansCells
    501. Carbonic anhydrase IX is an independent predictor of survival in advanced renal clear cell carcinoma: implications for prognosis and therapy. Clin Cancer Res. 2003 Feb; 9(2):802-11. Bui MH, Seligson D, Han KR, Pantuck AJ, Dorey FJ, Huang Y, Horvath S, Leibovich BC, Chopra S, Liao SY, Stanbridge E, Lerman MI, Palotie A, Figlin RA, Belldegrun AS. PMID: 12576453.
      View in: PubMed   Mentions: 207     Fields:    Translation:Humans
    502. Expression of colony-stimulating factor 1 receptor during prostate development and prostate cancer progression. Proc Natl Acad Sci U S A. 2002 Oct 29; 99(22):14404-9. Ide H, Seligson DB, Memarzadeh S, Xin L, Horvath S, Dubey P, Flick MB, Kacinski BM, Palotie A, Witte ON. PMID: 12381783; PMCID: PMC137896.
      View in: PubMed   Mentions: 51     Fields:    Translation:HumansAnimalsCells
    503. Tissue microarray analysis of cytoskeletal actin-associated biomarkers gelsolin and E-cadherin in urothelial carcinoma. Cancer. 2002 Sep 15; 95(6):1247-57. Rao J, Seligson D, Visapaa H, Horvath S, Eeva M, Michel K, Pantuck A, Belldegrun A, Palotie A. PMID: 12216092.
      View in: PubMed   Mentions: 25     Fields:    Translation:Humans
    504. The family based association test method: strategies for studying general genotype--phenotype associations. Eur J Hum Genet. 2001 Apr; 9(4):301-6. Horvath S, Xu X, Laird NM. PMID: 11313775.
      View in: PubMed   Mentions: 324     Fields:    Translation:Humans
    Steve's Networks
    Concepts (1122)
    Derived automatically from this person's publications.
    Explore
    _
    Co-Authors (206)
    People in Profiles who have published with this person.
    Explore
    _
    Similar People (60)
    People who share similar concepts with this person.
    Explore
    _
    Same Department
    Search Department
    _

    UCLA Profiles is managed by the UCSF Clinical and Translational Science Institute (CTSI), part of the Clinical and Translational Science Award program funded by the National Center for Advancing Translational Sciences (Grant Number UL1 TR000004) at the National Institutes of Health (NIH).
    This site is running Profiles RNS version UCSF-v3.1.0-40-gb10dcd06 on PROFILES-PWEB04. We use cookies to operate our website. We also use cookies to analyze our site’s performance and improve your experience on our site. For more information about how we use cookies, please see our Website Terms of Use.

    Copyright © The Regents of the University of California