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Eskin Eleazar

Title(s)Member, CTSI
SchoolCTSI
Phone(310) 594-5112
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    Other Positions
    Title(s)Associate Professor, Computer Science

    Title(s)Associate Professor, Human Genetics

    Title(s)Member, Bioinformatics GPB Home Area

    Title(s)Member, Genetics & Genomics GPB Home Area


    Collapse Research 
    Collapse Research Activities and Funding
    Genetic pathways for impulsivity and drug reinforcement: DNA and transcriptome variation in mice
    NIH/NIDA U01DA041602Sep 15, 2017 - May 31, 2022
    Role: Co-Principal Investigator
    Undergraduate Research Experience in Neuropsychiatric Genomics
    NIH/NIMH R25MH109172Feb 1, 2016 - Nov 30, 2020
    Role: Co-Principal Investigator
    Mathematical and Computational Approaches in High-Throughput Genomics Training
    NIH/NIGMS R25GM112625Sep 1, 2015 - Jun 30, 2020
    Role: Principal Investigator
    Correcting for Population Structure in Gene-by-Environment Interaction Studies
    NIH/NIEHS R01ES022282Sep 1, 2013 - Jun 30, 2016
    Role: Principal Investigator
    Discovering the Genetic Basis of Hypertension
    NIH/NHLBI K25HL080079Jun 1, 2006 - May 31, 2012
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
    List All   |   Timeline
    1. Lee C, Kang EY, Gandal MJ, Eskin E, Geschwind DH. Profiling allele-specific gene expression in brains from individuals with autism spectrum disorder reveals preferential minor allele usage. Nat Neurosci. 2019 09; 22(9):1521-1532. PMID: 31455884.
      View in: PubMed
    2. Yao DW, Balanis NG, Eskin E, Graeber TG. A linear mixed model approach to gene expression-tumor aneuploidy association studies. Sci Rep. 2019 Aug 16; 9(1):11944. PMID: 31420589.
      View in: PubMed
    3. Rahmani E, Schweiger R, Rhead B, Criswell LA, Barcellos LF, Eskin E, Rosset S, Sankararaman S, Halperin E. Cell-type-specific resolution epigenetics without the need for cell sorting or single-cell biology. Nat Commun. 2019 Jul 31; 10(1):3417. PMID: 31366909.
      View in: PubMed
    4. Mangul S, Mosqueiro T, Abdill RJ, Duong D, Mitchell K, Sarwal V, Hill B, Brito J, Littman RJ, Statz B, Lam AK, Dayama G, Grieneisen L, Martin LS, Flint J, Eskin E, Blekhman R. Challenges and recommendations to improve the installability and archival stability of omics computational tools. PLoS Biol. 2019 Jun; 17(6):e3000333. PMID: 31220077.
      View in: PubMed
    5. LaPierre N, Mangul S, Alser M, Mandric I, Wu NC, Koslicki D, Eskin E. MiCoP: microbial community profiling method for detecting viral and fungal organisms in metagenomic samples. BMC Genomics. 2019 Jun 06; 20(Suppl 5):423. PMID: 31167634.
      View in: PubMed
    6. Mangul S, Martin LS, Hill BL, Lam AK, Distler MG, Zelikovsky A, Eskin E, Flint J. Systematic benchmarking of omics computational tools. Nat Commun. 2019 03 27; 10(1):1393. PMID: 30918265.
      View in: PubMed
    7. Mangul S, Martin LS, Langmead B, Sanchez-Galan JE, Toma I, Hormozdiari F, Pevzner P, Eskin E. How bioinformatics and open data can boost basic science in countries and universities with limited resources. Nat Biotechnol. 2019 03; 37(3):324-326. PMID: 30833765.
      View in: PubMed
    8. Mangul S, Martin LS, Eskin E, Blekhman R. Improving the usability and archival stability of bioinformatics software. Genome Biol. 2019 02 27; 20(1):47. PMID: 30813962.
      View in: PubMed
    9. Sul JH, Martin LS, Eskin E. Population structure in genetic studies: Confounding factors and mixed models. PLoS Genet. 2018 12; 14(12):e1007309. PMID: 30589851.
      View in: PubMed
    10. Duong D, Ahmad WU, Eskin E, Chang KW, Li JJ. Word and Sentence Embedding Tools to Measure Semantic Similarity of Gene Ontology Terms by Their Definitions. J Comput Biol. 2019 01; 26(1):38-52. PMID: 30383443.
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    11. Wu Y, Hormozdiari F, Joo JWJ, Eskin E. Improving Imputation Accuracy by Inferring Causal Variants in Genetic Studies. J Comput Biol. 2018 Oct 01. PMID: 30272994.
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    12. Rahmani E, Schweiger R, Shenhav L, Wingert T, Hofer I, Gabel E, Eskin E, Halperin E. BayesCCE: a Bayesian framework for estimating cell-type composition from DNA methylation without the need for methylation reference. Genome Biol. 2018 09 21; 19(1):141. PMID: 30241486.
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    13. Gai L, Eskin E. Finding associated variants in genome-wide association studies on multiple traits. Bioinformatics. 2018 07 01; 34(13):i467-i474. PMID: 29949991.
      View in: PubMed
    14. Gamazon ER, Segrè AV, van de Bunt M, Wen X, Xi HS, Hormozdiari F, Ongen H, Konkashbaev A, Derks EM, Aguet F, Quan J, Nicolae DL, Eskin E, Kellis M, Getz G, McCarthy MI, Dermitzakis ET, Cox NJ, Ardlie KG. Using an atlas of gene regulation across 44 human tissues to inform complex disease- and trait-associated variation. Nat Genet. 2018 07; 50(7):956-967. PMID: 29955180.
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    15. Hormozdiari F, Gazal S, van de Geijn B, Finucane HK, Ju CJ, Loh PR, Schoech A, Reshef Y, Liu X, O'Connor L, Gusev A, Eskin E, Price AL. Leveraging molecular quantitative trait loci to understand the genetic architecture of diseases and complex traits. Nat Genet. 2018 07; 50(7):1041-1047. PMID: 29942083.
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    16. Kennedy EM, Goehring GN, Nichols MH, Robins C, Mehta D, Klengel T, Eskin E, Smith AK, Conneely KN. An integrated -omics analysis of the epigenetic landscape of gene expression in human blood cells. BMC Genomics. 2018 Jun 19; 19(1):476. PMID: 29914364.
      View in: PubMed
    17. Kang EY, Lee CH, Furlotte NA, Joo JWJ, Kostem E, Zaitlen N, Eskin E, Han B. An Association Mapping Framework To Account for Potential Sex Difference in Genetic Architectures. Genetics. 2018 07; 209(3):685-698. PMID: 29752291.
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    18. Olde Loohuis LM, Mangul S, Ori APS, Jospin G, Koslicki D, Yang HT, Wu T, Boks MP, Lomen-Hoerth C, Wiedau-Pazos M, Cantor RM, de Vos WM, Kahn RS, Eskin E, Ophoff RA. Transcriptome analysis in whole blood reveals increased microbial diversity in schizophrenia. Transl Psychiatry. 2018 05 10; 8(1):96. PMID: 29743478.
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    19. Mangul S, Martin LS, Eskin E. Involving undergraduates in genomics research to narrow the education-research gap. Nat Biotechnol. 2018 04 05; 36(4):369-371. PMID: 29621227.
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    20. Mangul S, Yang HT, Strauli N, Gruhl F, Porath HT, Hsieh K, Chen L, Daley T, Christenson S, Wesolowska-Andersen A, Spreafico R, Rios C, Eng C, Smith AD, Hernandez RD, Ophoff RA, Santana JR, Levanon EY, Woodruff PG, Burchard E, Seibold MA, Shifman S, Eskin E, Zaitlen N. ROP: dumpster diving in RNA-sequencing to find the source of 1 trillion reads across diverse adult human tissues. Genome Biol. 2018 02 15; 19(1):36. PMID: 29548336.
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    21. Park DS, Eskin I, Kang EY, Gamazon ER, Eng C, Gignoux CR, Galanter JM, Burchard E, Ye CJ, Aschard H, Eskin E, Halperin E, Zaitlen N. An ancestry-based approach for detecting interactions. Genet Epidemiol. 2018 02; 42(1):49-63. PMID: 29114909.
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    22. Jasinska AJ, Zelaya I, Service SK, Peterson CB, Cantor RM, Choi OW, DeYoung J, Eskin E, Fairbanks LA, Fears S, Furterer AE, Huang YS, Ramensky V, Schmitt CA, Svardal H, Jorgensen MJ, Kaplan JR, Villar D, Aken BL, Flicek P, Nag R, Wong ES, Blangero J, Dyer TD, Bogomolov M, Benjamini Y, Weinstock GM, Dewar K, Sabatti C, Wilson RK, Jentsch JD, Warren W, Coppola G, Woods RP, Freimer NB. Genetic variation and gene expression across multiple tissues and developmental stages in a nonhuman primate. Nat Genet. 2017 Dec; 49(12):1714-1721. PMID: 29083405.
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    23. Crawford NG, Kelly DE, Hansen MEB, Beltrame MH, Fan S, Bowman SL, Jewett E, Ranciaro A, Thompson S, Lo Y, Pfeifer SP, Jensen JD, Campbell MC, Beggs W, Hormozdiari F, Mpoloka SW, Mokone GG, Nyambo T, Meskel DW, Belay G, Haut J, Rothschild H, Zon L, Zhou Y, Kovacs MA, Xu M, Zhang T, Bishop K, Sinclair J, Rivas C, Elliot E, Choi J, Li SA, Hicks B, Burgess S, Abnet C, Watkins-Chow DE, Oceana E, Song YS, Eskin E, Brown KM, Marks MS, Loftus SK, Pavan WJ, Yeager M, Chanock S, Tishkoff SA. Loci associated with skin pigmentation identified in African populations. Science. 2017 11 17; 358(6365). PMID: 29025994.
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    24. Ritchie MD, Davis JR, Aschard H, Battle A, Conti D, Du M, Eskin E, Fallin MD, Hsu L, Kraft P, Moore JH, Pierce BL, Bien SA, Thomas DC, Wei P, Montgomery SB. Incorporation of Biological Knowledge Into the Study of Gene-Environment Interactions. Am J Epidemiol. 2017 Oct 01; 186(7):771-777. PMID: 28978191.
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    25. Mangul S, Martin LS, Hoffmann A, Pellegrini M, Eskin E. Addressing the Digital Divide in Contemporary Biology: Lessons from Teaching UNIX. Trends Biotechnol. 2017 10; 35(10):901-903. PMID: 28720283.
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    26. Duong D, Gai L, Snir S, Kang EY, Han B, Sul JH, Eskin E. Applying meta-analysis to genotype-tissue expression data from multiple tissues to identify eQTLs and increase the number of eGenes. Bioinformatics. 2017 Jul 15; 33(14):i67-i74. PMID: 28881962.
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    27. Buckley MT, Racimo F, Allentoft ME, Jensen MK, Jonsson A, Huang H, Hormozdiari F, Sikora M, Marnetto D, Eskin E, Jørgensen ME, Grarup N, Pedersen O, Hansen T, Kraft P, Willerslev E, Nielsen R. Selection in Europeans on Fatty Acid Desaturases Associated with Dietary Changes. Mol Biol Evol. 2017 06 01; 34(6):1307-1318. PMID: 28333262.
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    28. Hormozdiari F, Zhu A, Kichaev G, Ju CJ, Segrè AV, Joo JWJ, Won H, Sankararaman S, Pasaniuc B, Shifman S, Eskin E. Widespread Allelic Heterogeneity in Complex Traits. Am J Hum Genet. 2017 May 04; 100(5):789-802. PMID: 28475861.
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    29. He D, Wang Z, Parida L, Eskin E. IPED2: Inheritance Path Based Pedigree Reconstruction Algorithm for Complicated Pedigrees. IEEE/ACM Trans Comput Biol Bioinform. 2017 Sep-Oct; 14(5):1094-1103. PMID: 28368828.
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    30. Mangul S, Yang TH, Hormozdiari F, Dainis AM, Tseng E, Ashley EA, Zelikovsky A, Eskin E. HapIso: An Accurate Method for the Haplotype- Specific Isoforms Reconstruction From Long Single-Molecule Reads. IEEE Trans Nanobioscience. 2017 03; 16(2):108-115. PMID: 28328508.
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    31. Rahmani E, Zaitlen N, Baran Y, Eng C, Hu D, Galanter J, Oh S, Burchard EG, Eskin E, Zou J, Halperin E. Correcting for cell-type heterogeneity in DNA methylation: a comprehensive evaluation. Nat Methods. 2017 02 28; 14(3):218-219. PMID: 28245214.
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    32. Bilow M, Crespo F, Pan Z, Eskin E, Eyheramendy S. Simultaneous Modeling of Disease Status and Clinical Phenotypes To Increase Power in Genome-Wide Association Studies. Genetics. 2017 03; 205(3):1041-1047. PMID: 28132020.
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    33. Artyomenko A, Wu NC, Mangul S, Eskin E, Sun R, Zelikovsky A. Long Single-Molecule Reads Can Resolve the Complexity of the Influenza Virus Composed of Rare, Closely Related Mutant Variants. J Comput Biol. 2017 Jun; 24(6):558-570. PMID: 27901586.
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    34. Hormozdiari F, van de Bunt M, Segrè AV, Li X, Joo JWJ, Bilow M, Sul JH, Sankararaman S, Pasaniuc B, Eskin E. Colocalization of GWAS and eQTL Signals Detects Target Genes. Am J Hum Genet. 2016 Dec 01; 99(6):1245-1260. PMID: 27866706.
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    35. Joo JW, Kang EY, Org E, Furlotte N, Parks B, Hormozdiari F, Lusis AJ, Eskin E. Efficient and Accurate Multiple-Phenotype Regression Method for High Dimensional Data Considering Population Structure. Genetics. 2016 Dec; 204(4):1379-1390. PMID: 27770036.
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    36. Won H, de la Torre-Ubieta L, Stein JL, Parikshak NN, Huang J, Opland CK, Gandal MJ, Sutton GJ, Hormozdiari F, Lu D, Lee C, Eskin E, Voineagu I, Ernst J, Geschwind DH. Chromosome conformation elucidates regulatory relationships in developing human brain. Nature. 2016 10 27; 538(7626):523-527. PMID: 27760116.
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    37. Lavinsky J, Ge M, Crow AL, Pan C, Wang J, Salehi P, Myint A, Eskin E, Allayee H, Lusis AJ, Friedman RA. The Genetic Architecture of Noise-Induced Hearing Loss: Evidence for a Gene-by-Environment Interaction. G3 (Bethesda). 2016 10 13; 6(10):3219-3228. PMID: 27520957.
      View in: PubMed
    38. Kang EY, Martin LJ, Mangul S, Isvilanonda W, Zou J, Ben-David E, Han B, Lusis AJ, Shifman S, Eskin E. Discovering Single Nucleotide Polymorphisms Regulating Human Gene Expression Using Allele Specific Expression from RNA-seq Data. Genetics. 2016 11; 204(3):1057-1064. PMID: 27765809.
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    39. Kichaev G, Roytman M, Johnson R, Eskin E, Lindström S, Kraft P, Pasaniuc B. Improved methods for multi-trait fine mapping of pleiotropic risk loci. Bioinformatics. 2017 01 15; 33(2):248-255. PMID: 27663501.
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    40. Main BJ, Lee Y, Ferguson HM, Kreppel KS, Kihonda A, Govella NJ, Collier TC, Cornel AJ, Eskin E, Kang EY, Nieman CC, Weakley AM, Lanzaro GC. The Genetic Basis of Host Preference and Resting Behavior in the Major African Malaria Vector, Anopheles arabiensis. PLoS Genet. 2016 09; 12(9):e1006303. PMID: 27631375.
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    41. Hasin-Brumshtein Y, Khan AH, Hormozdiari F, Pan C, Parks BW, Petyuk VA, Piehowski PD, Brümmer A, Pellegrini M, Xiao X, Eskin E, Smith RD, Lusis AJ, Smith DJ. Hypothalamic transcriptomes of 99 mouse strains reveal trans eQTL hotspots, splicing QTLs and novel non-coding genes. Elife. 2016 09 13; 5. PMID: 27623010.
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    42. Kang EY, Park Y, Li X, Segrè AV, Han B, Eskin E. ForestPMPlot: A Flexible Tool for Visualizing Heterogeneity Between Studies in Meta-analysis. G3 (Bethesda). 2016 07 07; 6(7):1793-8. PMID: 27194809.
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    43. Duong D, Zou J, Hormozdiari F, Sul JH, Ernst J, Han B, Eskin E. Using genomic annotations increases statistical power to detect eGenes. Bioinformatics. 2016 06 15; 32(12):i156-i163. PMID: 27307612.
      View in: PubMed
    44. Hormozdiari F, Kang EY, Bilow M, Ben-David E, Vulpe C, McLachlan S, Lusis AJ, Han B, Eskin E. Imputing Phenotypes for Genome-wide Association Studies. Am J Hum Genet. 2016 Jul 07; 99(1):89-103. PMID: 27292110.
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    45. Schweiger R, Kaufman S, Laaksonen R, Kleber ME, März W, Eskin E, Rosset S, Halperin E. Fast and Accurate Construction of Confidence Intervals for Heritability. Am J Hum Genet. 2016 06 02; 98(6):1181-1192. PMID: 27259052.
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    46. Peterson CB, Service SK, Jasinska AJ, Gao F, Zelaya I, Teshiba TM, Bearden CE, Cantor RM, Reus VI, Macaya G, López-Jaramillo C, Bogomolov M, Benjamini Y, Eskin E, Coppola G, Freimer NB, Sabatti C. Characterization of Expression Quantitative Trait Loci in Pedigrees from Colombia and Costa Rica Ascertained for Bipolar Disorder. PLoS Genet. 2016 05; 12(5):e1006046. PMID: 27176483.
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    47. Lusis AJ, Seldin MM, Allayee H, Bennett BJ, Civelek M, Davis RC, Eskin E, Farber CR, Hui S, Mehrabian M, Norheim F, Pan C, Parks B, Rau CD, Smith DJ, Vallim T, Wang Y, Wang J. The Hybrid Mouse Diversity Panel: a resource for systems genetics analyses of metabolic and cardiovascular traits. J Lipid Res. 2016 06; 57(6):925-42. PMID: 27099397.
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    48. Joo JW, Hormozdiari F, Han B, Eskin E. Multiple testing correction in linear mixed models. Genome Biol. 2016 Apr 01; 17:62. PMID: 27039378.
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    49. Rahmani E, Zaitlen N, Baran Y, Eng C, Hu D, Galanter J, Oh S, Burchard EG, Eskin E, Zou J, Halperin E. Sparse PCA corrects for cell type heterogeneity in epigenome-wide association studies. Nat Methods. 2016 05; 13(5):443-5. PMID: 27018579.
      View in: PubMed
    50. Sul JH, Bilow M, Yang WY, Kostem E, Furlotte N, He D, Eskin E. Accounting for Population Structure in Gene-by-Environment Interactions in Genome-Wide Association Studies Using Mixed Models. PLoS Genet. 2016 Mar; 12(3):e1005849. PMID: 26943367.
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    51. Bennett BJ, Davis RC, Civelek M, Orozco L, Wu J, Qi H, Pan C, Sevag Packard RR, Eskin E, Yan M, Kirchgessner T, Wang Z, Li X, Gregory JC, Hazen SL, Gargalovic PS, Lusis AJ. Correction: Genetic Architecture of Atherosclerosis in Mice: A Systems Genetics Analysis of Common Inbred Strains. PLoS Genet. 2016 Mar; 12(3):e1005913. PMID: 26934746.
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    52. Han B, Duong D, Sul JH, de Bakker PI, Eskin E, Raychaudhuri S. A general framework for meta-analyzing dependent studies with overlapping subjects in association mapping. Hum Mol Genet. 2016 05 01; 25(9):1857-66. PMID: 26908615.
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    53. Bennett BJ, Davis RC, Civelek M, Orozco L, Wu J, Qi H, Pan C, Packard RR, Eskin E, Yan M, Kirchgessner T, Wang Z, Li X, Gregory JC, Hazen SL, Gargalovic PS, Lusis AJ. Genetic Architecture of Atherosclerosis in Mice: A Systems Genetics Analysis of Common Inbred Strains. PLoS Genet. 2015 Dec; 11(12):e1005711. PMID: 26694027.
      View in: PubMed
    54. Crow AL, Ohmen J, Wang J, Lavinsky J, Hartiala J, Li Q, Li X, Salehide P, Eskin E, Pan C, Lusis AJ, Allayee H, Friedman RA. The Genetic Architecture of Hearing Impairment in Mice: Evidence for Frequency-Specific Genetic Determinants. G3 (Bethesda). 2015 Sep 04; 5(11):2329-39. PMID: 26342000.
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    55. Org E, Parks BW, Joo JW, Emert B, Schwartzman W, Kang EY, Mehrabian M, Pan C, Knight R, Gunsalus R, Drake TA, Eskin E, Lusis AJ. Genetic and environmental control of host-gut microbiota interactions. Genome Res. 2015 Oct; 25(10):1558-69. PMID: 26260972.
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    56. Rau CD, Parks B, Wang Y, Eskin E, Simecek P, Churchill GA, Lusis AJ. High-Density Genotypes of Inbred Mouse Strains: Improved Power and Precision of Association Mapping. G3 (Bethesda). 2015 Jul 28; 5(10):2021-6. PMID: 26224782.
      View in: PubMed
    57. Nanda V, Gutman B, Bar E, Alghamdi S, Tetradis S, Lusis AJ, Eskin E, Moon W. Quantitative analysis of 3-dimensional facial soft tissue photographic images: technical methods and clinical application. Prog Orthod. 2015; 16:21. PMID: 26133934.
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    58. Hormozdiari F, Kichaev G, Yang WY, Pasaniuc B, Eskin E. Identification of causal genes for complex traits. Bioinformatics. 2015 Jun 15; 31(12):i206-13. PMID: 26072484.
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    59. Lavinsky J, Crow AL, Pan C, Wang J, Aaron KA, Ho MK, Li Q, Salehide P, Myint A, Monges-Hernadez M, Eskin E, Allayee H, Lusis AJ, Friedman RA. Correction: Genome-Wide Association Study Identifies Nox3 as a Critical Gene for Susceptibility to Noise-Induced Hearing Loss. PLoS Genet. 2015 Jun; 11(6):e1005293. PMID: 26068505.
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    60. Zhou X, Crow AL, Hartiala J, Spindler TJ, Ghazalpour A, Barsky LW, Bennett BJ, Parks BW, Eskin E, Jain R, Epstein JA, Lusis AJ, Adams GB, Allayee H. The Genetic Landscape of Hematopoietic Stem Cell Frequency in Mice. Stem Cell Reports. 2015 Jul 14; 5(1):125-38. PMID: 26050929.
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    61. Sul JH, Raj T, de Jong S, de Bakker PI, Raychaudhuri S, Ophoff RA, Stranger BE, Eskin E, Han B. Accurate and fast multiple-testing correction in eQTL studies. Am J Hum Genet. 2015 Jun 04; 96(6):857-68. PMID: 26027500.
      View in: PubMed
    62. Lavinsky J, Crow AL, Pan C, Wang J, Aaron KA, Ho MK, Li Q, Salehide P, Myint A, Monges-Hernadez M, Eskin E, Allayee H, Lusis AJ, Friedman RA. Genome-wide association study identifies nox3 as a critical gene for susceptibility to noise-induced hearing loss. PLoS Genet. 2015 Apr; 11(4):e1005094. PMID: 25880434.
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    63. Wang Z, Sul JH, Snir S, Lozano JA, Eskin E. Gene-Gene Interactions Detection Using a Two-stage Model. J Comput Biol. 2015 Jun; 22(6):563-76. PMID: 25871811.
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    64. Furlotte NA, Eskin E. Efficient multiple-trait association and estimation of genetic correlation using the matrix-variate linear mixed model. Genetics. 2015 May; 200(1):59-68. PMID: 25724382.
      View in: PubMed
    65. Yang WY, Hormozdiari F, Eskin E, Pasaniuc B. A spatial haplotype copying model with applications to genotype imputation. J Comput Biol. 2015 May; 22(5):451-62. PMID: 25526526.
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    66. Hormozdiari F, Eskin E. Memory efficient assembly of human genome. J Bioinform Comput Biol. 2015 Apr; 13(2):1550008. PMID: 25603998.
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    67. He D, Eskin E. IPED2X: a robust pedigree reconstruction algorithm for complicated pedigrees. J Bioinform Comput Biol. 2014 Dec; 12(6):1442007. PMID: 25553812.
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    68. Yang WY, Platt A, Chiang CW, Eskin E, Novembre J, Pasaniuc B. Spatial localization of recent ancestors for admixed individuals. G3 (Bethesda). 2014 Nov 03; 4(12):2505-18. PMID: 25371484.
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    69. Kichaev G, Yang WY, Lindstrom S, Hormozdiari F, Eskin E, Price AL, Kraft P, Pasaniuc B. Integrating functional data to prioritize causal variants in statistical fine-mapping studies. PLoS Genet. 2014 Oct; 10(10):e1004722. PMID: 25357204.
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    70. Hormozdiari F, Kostem E, Kang EY, Pasaniuc B, Eskin E. Identifying causal variants at loci with multiple signals of association. Genetics. 2014 Oct; 198(2):497-508. PMID: 25104515.
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    71. Hormozdiari F, Joo JW, Wadia A, Guan F, Ostrosky R, Sahai A, Eskin E. Privacy preserving protocol for detecting genetic relatives using rare variants. Bioinformatics. 2014 Jun 15; 30(12):i204-11. PMID: 24931985.
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    72. Mangul S, Wu NC, Mancuso N, Zelikovsky A, Sun R, Eskin E. Accurate viral population assembly from ultra-deep sequencing data. Bioinformatics. 2014 Jun 15; 30(12):i329-37. PMID: 24932001.
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    73. Hasin-Brumshtein Y, Hormozdiari F, Martin L, van Nas A, Eskin E, Lusis AJ, Drake TA. Allele-specific expression and eQTL analysis in mouse adipose tissue. BMC Genomics. 2014 Jun 13; 15:471. PMID: 24927774.
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    74. Joo JW, Sul JH, Han B, Ye C, Eskin E. Effectively identifying regulatory hotspots while capturing expression heterogeneity in gene expression studies. Genome Biol. 2014 Apr 07; 15(4):r61. PMID: 24708878.
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    75. He D, Furlotte NA, Hormozdiari F, Joo JW, Wadia A, Ostrovsky R, Sahai A, Eskin E. Identifying genetic relatives without compromising privacy. Genome Res. 2014 Apr; 24(4):664-72. PMID: 24614977.
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    76. Ohmen J, Kang EY, Li X, Joo JW, Hormozdiari F, Zheng QY, Davis RC, Lusis AJ, Eskin E, Friedman RA. Genome-wide association study for age-related hearing loss (AHL) in the mouse: a meta-analysis. J Assoc Res Otolaryngol. 2014 Jun; 15(3):335-52. PMID: 24570207.
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    77. Zhang K, Huentelman MJ, Rao F, Sun EI, Corneveaux JJ, Schork AJ, Wei Z, Waalen J, Miramontes-Gonzalez JP, Hightower CM, Maihofer AX, Mahata M, Pastinen T, Ehret GB, Schork NJ, Eskin E, Nievergelt CM, Saier MH, O'Connor DT. Genetic implication of a novel thiamine transporter in human hypertension. J Am Coll Cardiol. 2014 Apr 22; 63(15):1542-55. PMID: 24509276.
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    78. Marsden CD, Lee Y, Kreppel K, Weakley A, Cornel A, Ferguson HM, Eskin E, Lanzaro GC. Diversity, differentiation, and linkage disequilibrium: prospects for association mapping in the malaria vector Anopheles arabiensis. G3 (Bethesda). 2014 Jan 10; 4(1):121-31. PMID: 24281424.
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    79. Kang EY, Han B, Furlotte N, Joo JW, Shih D, Davis RC, Lusis AJ, Eskin E. Meta-analysis identifies gene-by-environment interactions as demonstrated in a study of 4,965 mice. PLoS Genet. 2014 Jan; 10(1):e1004022. PMID: 24415945.
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    80. Han B, Kang EY, Raychaudhuri S, de Bakker PI, Eskin E. Fast pairwise IBD association testing in genome-wide association studies. Bioinformatics. 2014 Jan 15; 30(2):206-13. PMID: 24158599.
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    81. Eskin I, Hormozdiari F, Conde L, Riby J, Skibola CF, Eskin E, Halperin E. eALPS: estimating abundance levels in pooled sequencing using available genotyping data. J Comput Biol. 2013 Nov; 20(11):861-77. PMID: 24144111.
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    119. Van Tyne D, Park DJ, Schaffner SF, Neafsey DE, Angelino E, Cortese JF, Barnes KG, Rosen DM, Lukens AK, Daniels RF, Milner DA, Johnson CA, Shlyakhter I, Grossman SR, Becker JS, Yamins D, Karlsson EK, Ndiaye D, Sarr O, Mboup S, Happi C, Furlotte NA, Eskin E, Kang HM, Hartl DL, Birren BW, Wiegand RC, Lander ES, Wirth DF, Volkman SK, Sabeti PC. Identification and functional validation of the novel antimalarial resistance locus PF10_0355 in Plasmodium falciparum. PLoS Genet. 2011 Apr; 7(4):e1001383. PMID: 21533027.
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    149. Barrett TB, Emberton JE, Nievergelt CM, Liang SG, Hauger RL, Eskin E, Schork NJ, Kelsoe JR. Further evidence for association of GRK3 to bipolar disorder suggests a second disease mutation. Psychiatr Genet. 2007 Dec; 17(6):315-22. PMID: 18075471.
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    150. Frazer KA, Eskin E, Kang HM, Bogue MA, Hinds DA, Beilharz EJ, Gupta RV, Montgomery J, Morenzoni MM, Nilsen GB, Pethiyagoda CL, Stuve LL, Johnson FM, Daly MJ, Wade CM, Cox DR. A sequence-based variation map of 8.27 million SNPs in inbred mouse strains. Nature. 2007 Aug 30; 448(7157):1050-3. PMID: 17660834.
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    163. Price AL, Eskin E, Pevzner PA. Whole-genome analysis of Alu repeat elements reveals complex evolutionary history. Genome Res. 2004 Nov; 14(11):2245-52. PMID: 15520288.
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    165. Leslie CS, Eskin E, Cohen A, Weston J, Noble WS. Mismatch string kernels for discriminative protein classification. Bioinformatics. 2004 Mar 01; 20(4):467-76. PMID: 14990442.
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    166. Eskin E, Halperin E, Karp RM. Efficient reconstruction of haplotype structure via perfect phylogeny. J Bioinform Comput Biol. 2003 Apr; 1(1):1-20. PMID: 15290779.
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    167. Eskin E, Keich U, Gelfand MS, Pevzner PA. Genome-wide analysis of bacterial promoter regions. Pac Symp Biocomput. 2003; 29-40. PMID: 12603015.
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