Timothy Chang

Title(s)Assistant Professor-in-Residence, Neurology
ORCID ORCID Icon0000-0002-9225-9874 Additional info
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    Collapse Biography 
    Collapse Education and Training
    University of Wisconsin, Madison, MadisonMD06/2014
    University of Wisconsin, Madison, MadisonPhD06/2012Clinical Investigation (Biomedical Informatics)
    UCLA, Los Angeles2018Neurology
    UCLA, Los Angeles2020Fellowship Movement Disorder
    UCLA, Los Angeles2021Fellowship Neurobehavior

    Collapse Overview 
    Collapse Overview
    The goal of our research laboratory is to incorporate genomics, electronic health records, and biomedical informatics to realize precision medicine for neurodegenerative diseases. To work toward this goal, we leverage our biological and clinical understanding of disease, and ability to apply state-of-the-art biomedical informatic methods to enhance novel discoveries. In addition to research, I am a movement disorder and neurobehavior physician, actively seeing patients with Alzheimer’s disease, dementias and atypical Parkinsonian disorders.

    Dr. Chang holds the Augustus S. Rose Chair in Neurology.

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    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Defining the distance between diseases using SNOMED CT embeddings. J Biomed Inform. 2023 03; 139:104307. Fu M, Yan Y, Olde Loohuis LM, Chang TS. PMID: 36738869.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    2. Phenome-Wide Association Study of Polygenic Risk Score for Alzheimer's Disease in Electronic Health Records. Front Aging Neurosci. 2022; 14:800375. Fu M, UCLA Precision Health Data Discovery Repository Working Group, UCLA Precision Health ATLAS Working Group, Chang TS. PMID: 35370621; PMCID: PMC8965623.
      View in: PubMed   Mentions: 2  
    3. Pre-existing conditions in Hispanics/Latinxs that are COVID-19 risk factors. iScience. 2021 Mar 19; 24(3):102188. Chang TS, Ding Y, Freund MK, Johnson R, Schwarz T, Yabu JM, Hazlett C, Chiang JN, Wulf DA, UCLA Precision Health Data Discovery Repository Working Group, Geschwind DH, Butte MJ, Pasaniuc B. PMID: 33615196; PMCID: PMC7879099.
      View in: PubMed   Mentions: 8  
    4. Tau Pathology Drives Dementia Risk-Associated Gene Networks toward Chronic Inflammatory States and Immunosuppression. Cell Rep. 2020 11 17; 33(7):108398. Rexach JE, Polioudakis D, Yin A, Swarup V, Chang TS, Nguyen T, Sarkar A, Chen L, Huang J, Lin LC, Seeley W, Trojanowski JQ, Malhotra D, Geschwind DH. PMID: 33207193; PMCID: PMC7842189.
      View in: PubMed   Mentions: 41     Fields:    Translation:HumansAnimalsCells
    5. Prior diagnoses and medications as risk factors for COVID-19 in a Los Angeles Health System. medRxiv. 2020 Jul 09. Chang TS, Ding Y, Freund MK, Johnson R, Schwarz T, Yabu JM, Hazlett C, Chiang JN, Wulf A, UCLA Health Data Mart Working Group, Geschwind DH, Butte MJ, Pasaniuc B. PMID: 32637977; PMCID: PMC7340203.
      View in: PubMed   Mentions: 3  
    6. Identification of Conserved Proteomic Networks in Neurodegenerative Dementia. Cell Rep. 2020 06 23; 31(12):107807. Swarup V, Chang TS, Duong DM, Dammer EB, Dai J, Lah JJ, Johnson ECB, Seyfried NT, Levey AI, Geschwind DH. PMID: 32579933; PMCID: PMC8221021.
      View in: PubMed   Mentions: 29     Fields:    Translation:HumansCells
    7. Physicians Voluntarily Using an EHR-Based CDS Tool Improved Patients' Guideline-Related Statin Prescription Rates: A Retrospective Cohort Study. Appl Clin Inform. 2019 05; 10(3):421-445. Chang TS, Buchipudi A, Fonarow GC, Pfeffer MA, Singer JS, Cheng EM. PMID: 31216590; PMCID: PMC6584145.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    8. Optimizing Effect Sizes With Imaging Enrichment and Outcome Choices for Mild Alzheimer Disease Clinical Trials. Alzheimer Dis Assoc Disord. 2017 Jan-Mar; 31(1):19-26. Chang TS, Teng E, Elashoff D, Grill JD, Alzheimer’s Disease Neuroimaging Initiative. PMID: 27196535; PMCID: PMC5116001.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans