Bogdan Pasaniuc

Title(s)Professor, Pathology and Laboratory Medicine
SchoolMedicine
ORCID ORCID Icon0000-0002-0227-2056 Additional info
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    Other Positions
    Title(s)Professor, Human Genetics

    Title(s)Professor, Computational Medicine


    Collapse Biography 
    Collapse education and training
    Harvard School of Public Health, MAPostdoctoral Fellow2012Statistical Genetics
    Broad Institute of Harvard and MIT, MAPostdoctoral Fellow2012Population and Medical Genetics
    ICSI, UC Berkeley, CAPostdoctoral Fellow2010Computational Biology
    University of Connecticut, CTPhD2008Computer Science and Bioinformatics
    A.I.Cuza University of Iasi , RomaniaBSc2003Computer Science

    Collapse Overview 
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    Dr Pasaniuc is an professor of Computational Medicine, Human Genetics and Pathology&Laboratory Medicine at UCLA. Dr Pasaniuc develops statistical and computational methods to understand the genetic basis of disease, focusing on under-represented populations, integrative genomics, and biobank studies. Dr Pasaniuc group developed machine learning methods to integrate epigenetic profiles within trans-ancestry studies to localize disease variants and genes; his group introduced transcriptome-wide association studies (TWAS) using predicted gene expression as a principled approach to identify disease genes for many traits such as Schizophrenia, Ovarian Cancer and Prostate Cancer. Dr Pasaniuc serves as Associate Director of Population Genetics of the Institute for Precision Health at UCLA that links the genetics of more than 150k patients with their electronic health record to predict health outcomes, to stratify patients based on their genetic risk to disease and to translate genomics to the clinic. Dr Pasaniuc also serves as PI for the Center for Admixed populations and Health Equity and for the Biomedical Data Science Training Program for Precision Health Equity at UCLA.
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    PRS Center for Admixed Populations and Health Equity (CAPE)
    NIH U01HG011715Jun 8, 2021 - Mar 31, 2026
    Role: Principal Investigator
    Elucidation of the genetic mechanisms driving prostate tumorigenesis through integrative computational and functional approaches
    NIH R01CA251555Mar 2, 2021 - Feb 28, 2026
    Role: Co-Principal Investigator
    Collaborative multi-site project to speed the identification and management of rare genetic immune diseases
    NIH R01AI153827Feb 25, 2021 - Jan 31, 2026
    Role: Co-Principal Investigator
    Joint genomic and statistical analyses of schizophrenia and bipolar to decipher genetic susceptibility
    NIH R01MH115676Apr 1, 2018 - Jan 31, 2023
    Role: Co-Principal Investigator
    The Role of Splice Quantitative Traits in Ovarian Cancer Pathogenesis
    NIH R21CA220078Jun 15, 2017 - May 31, 2019
    Role: Co-Principal Investigator
    Integrative approaches for mapping the genetic risk of complex traits
    NIH R01HG009120Mar 1, 2017 - Feb 28, 2022
    Role: Principal Investigator
    Metrics and methods for cross-population fine mapping
    NIH R03CA162200Sep 12, 2012 - Aug 31, 2014
    Role: Principal Investigator

    Collapse ORNG Applications 
    Collapse Featured Publications

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
    Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Association between plausible genetic factors and weight loss from GLP1-RA and bariatric surgery. Nat Med. 2025 Apr 18. German J, Cordioli M, Tozzo V, Urbut S, Arumäe K, Smit RAJ, Lee J, Li JH, Janucik A, Ding Y, Akinkuolie A, Heyne HO, Eoli A, Saad C, Al-Sarraj Y, Abdel-Latif R, Mohammed S, Hail MA, Barry A, Wang Z, Cajuso T, Corbetta A, Natarajan P, Ripatti S, Philippakis A, Szczerbinski L, Pasaniuc B, Kutalik Z, Mbarek H, Loos RJF, Vainik U, Ganna A. PMID: 40251273.
      View in: PubMed   Mentions:    Fields:    
    2. Inclusion bias affects common variant discovery and replication in a health-system linked biobank. medRxiv. 2025 Apr 06. Pimplaskar A, Qiu J, Lapinska S, Tozzo V, Chiang JN, Pasaniuc B, Olde Loohuis LM. PMID: 40236437; PMCID: PMC11998835.
      View in: PubMed   Mentions:
    3. Large-scale admixture mapping in the All of Us Research Program improves the characterization of cross-population phenotypic differences. medRxiv. 2025 Apr 03. Mandla R, Shi Z, Hou K, Wang Y, Mies G, Aw AJ, Cullina S, Penn Medicine BioBank, Kenny E, Atkinson E, Martin AR, Pasaniuc B. PMID: 40236441; PMCID: PMC11998848.
      View in: PubMed   Mentions:
    4. Differential performance of polygenic prediction across traits and populations depending on genotype discovery approach. bioRxiv. 2025 Mar 18. Lin YS, Tan T, Wang Y, Pasaniuc B, Martin AR, Atkinson EG. PMID: 40166153; PMCID: PMC11957064.
      View in: PubMed   Mentions:
    5. The Germline and Somatic Origins of Prostate Cancer Heterogeneity. Cancer Discov. 2025 Feb 13. Yamaguchi TN, Houlahan KE, Zhu H, Kurganovs N, Livingstone J, Fox NS, Yuan J, Sietsma Penington J, Jung CH, Schwarz T, Jaratlerdsiri W, van Riet J, Georgeson P, Mangiola S, Taraszka K, Lesurf R, Jiang J, Chow K, Heisler LE, Shiah YJ, Ramanand SG, Clarkson MJ, Nguyen A, Espiritu SMG, Stuchbery R, Jovelin R, Huang V, Bell C, O'Connor E, McCoy PJ, Lalansingh CM, Cmero M, Salcedo A, Chan EKF, Liu LY, Stricker PD, Bhandari V, Bornman RMS, Sendorek DH, Lonie A, Prokopec SD, Fraser M, Peters JS, Foucal A, Mutambirwa SBA, Mcintosh L, Orain M, Wakefield M, Picard V, Park DJ, Hovington H, Kerger M, Bergeron A, Sabelnykova V, Seo JH, Pomerantz MM, Zaitlen N, Waszak SM, Gusev A, Lacombe L, Fradet Y, Ryan A, Kishan AU, Lolkema MP, Weischenfeldt J, Têtu B, Costello AJ, Hayes VM, Hung RJ, He HH, McPherson JD, Pasaniuc B, van der Kwast T, Papenfuss AT, Freedman ML, Pope BJ, Bristow RG, Mani RS, Corcoran NM, Reimand J, Hovens CM, Boutros PC. PMID: 39945744.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    6. PennPRS: a centralized cloud computing platform for efficient polygenic risk score training in precision medicine. medRxiv. 2025 Feb 10. Jin J, Li B, Wang X, Yang X, Li Y, Wang R, Ye C, Shu J, Fan Z, Xue F, Ge T, Ritchie MD, Pasaniuc B, Wojcik G, Zhao B. PMID: 39990574; PMCID: PMC11844566.
      View in: PubMed   Mentions:
    7. Association between plausible genetic factors and weight loss from GLP1-RA and bariatric surgery: a multi-ancestry study in 10 960 individuals from 9 biobanks. medRxiv. 2025 Jan 08. German J, Cordioli M, Tozzo V, Urbut S, Arumäe K, Smit RAJ, Lee J, Li JH, Janucik A, Ding Y, Akinkuolie A, Heyne H, Eoli A, Saad C, Al-Sarraj Y, Abdel-Latif R, Mohammed S, Hail MA, Barry A, Wang Z, Estonian Biobank research team, Cajuso T, Corbetta A, Natarajan P, Ripatti S, Philippakis A, Szczerbinski L, Pasaniuc B, Kutalik Z, Mbarek H, Loos RJF, Vainik U, Ganna A. PMID: 39314946; PMCID: PMC11419199.
      View in: PubMed   Mentions:
    8. Evaluating Performance and Agreement of Coronary Heart Disease Polygenic Risk Scores. JAMA. 2025 01 07; 333(1):60-70. Abramowitz SA, Boulier K, Keat K, Cardone KM, Shivakumar M, DePaolo J, Judy R, Bermudez F, Mimouni N, Neylan C, Kim D, Rader DJ, Ritchie MD, Voight BF, Pasaniuc B, Levin MG, Damrauer SM, Penn Medicine BioBank. PMID: 39549270; PMCID: PMC11569413.
      View in: PubMed   Mentions: 2     Fields:    
    9. Session Introduction: Overcoming health disparities in precision medicine: Intersectional approaches in precision medicine. Pac Symp Biocomput. 2025; 30:247-250. De La Vega FM, Barnes KC, Bland H, Edwards T, Fox K, Ioannidis A, Kenny E, Mathias RA, Pasaniuc B, Torres JB, Velez Edwards DR. PMID: 39670374.
      View in: PubMed   Mentions:    Fields:    
    10. Isoform-level analyses of 6 cancers uncover extensive genetic risk mechanisms undetected at the gene-level. medRxiv. 2024 Oct 30. Chang YH, Head ST, Harrison T, Yu Y, Huff CD, Pasaniuc B, Lindström S, Bhattacharya A. PMID: 39574839; PMCID: PMC11581093.
      View in: PubMed   Mentions:
    11. Population Performance and Individual Agreement of Coronary Artery Disease Polygenic Risk Scores. medRxiv. 2024 Oct 17. Abramowitz SA, Boulier K, Keat K, Cardone KM, Shivakumar M, DePaolo J, Judy R, Kim D, Rader DJ, Ritchie MD, Voight BF, Pasaniuc B, Levin MG, Damrauer SM. PMID: 39108513; PMCID: PMC11302700.
      View in: PubMed   Mentions:
    12. Advancing Mental Health Research Through Strategic Integration of Transdiagnostic Dimensions and Genomics. Biol Psychiatry. 2025 Mar 01; 97(5):450-460. Doyle AE, Bearden CE, Gur RE, Ledbetter DH, Martin CL, McCoy TH, Pasaniuc B, Perlis RH, Smoller JW, Davis LK. PMID: 39424167.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    13. Temporally distinct 3D multi-omic dynamics in the developing human brain. Nature. 2024 Nov; 635(8038):481-489. Heffel MG, Zhou J, Zhang Y, Lee DS, Hou K, Pastor-Alonso O, Abuhanna KD, Galasso J, Kern C, Tai CY, Garcia-Padilla C, Nafisi M, Zhou Y, Schmitt AD, Li T, Haeussler M, Wick B, Zhang MJ, Xie F, Ziffra RS, Mukamel EA, Eskin E, Nowakowski TJ, Dixon JR, Pasaniuc B, Ecker JR, Zhu Q, Bintu B, Paredes MF, Luo C. PMID: 39385032; PMCID: PMC11560841.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
    14. Multi-trait and multi-ancestry genetic analysis of comorbid lung diseases and traits improves genetic discovery and polygenic risk prediction. medRxiv. 2024 Sep 10. He Y, Lu W, Jee YH, Wang Y, Tsuo K, Qian DC, Diao JA, Huang H, Patel CJ, Byun J, Pasaniuc B, Atkinson EG, Amos CI, Moll M, Cho MH, Martin AR. PMID: 39252935; PMCID: PMC11383478.
      View in: PubMed   Mentions:
    15. Multi-ancestry polygenic risk scores for venous thromboembolism. Hum Mol Genet. 2024 09 03; 33(18):1584-1591. Jee YH, Thibord F, Dominguez A, Sept C, Boulier K, Venkateswaran V, Ding Y, Cherlin T, Verma SS, Faro VL, Bartz TM, Boland A, Brody JA, Deleuze JF, Emmerich J, Germain M, Johnson AD, Kooperberg C, Morange PE, Pankratz N, Psaty BM, Reiner AP, Smadja DM, Sitlani CM, Suchon P, Tang W, Trégouët DA, Zöllner S, Pasaniuc B, Damrauer SM, Sanna S, Snieder H, Lifelines Cohort Study, Kabrhel C, Smith NL, Kraft P, INVENT Consortium. PMID: 38879759; PMCID: PMC11373328.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    16. Improving genetic risk modeling of dementia from real-world data in underrepresented populations. Commun Biol. 2024 08 25; 7(1):1049. Fu M, Valiente-Banuet L, Wadhwa SS, Pasaniuc B, Vossel K, Chang TS. PMID: 39183196; PMCID: PMC11345412.
      View in: PubMed   Mentions: Translation:Humans
    17. All of Us diversity and scale improve polygenic prediction contextually with greatest improvements for under-represented populations. bioRxiv. 2024 Aug 06. Tsuo K, Shi Z, Ge T, Mandla R, Hou K, Ding Y, Pasaniuc B, Wang Y, Martin AR. PMID: 39149254; PMCID: PMC11326295.
      View in: PubMed   Mentions:
    18. Splicing-specific transcriptome-wide association uncovers genetic mechanisms for schizophrenia. Am J Hum Genet. 2024 Aug 08; 111(8):1573-1587. Hervoso JL, Amoah K, Dodson J, Choudhury M, Bhattacharya A, Quinones-Valdez G, Pasaniuc B, Xiao X. PMID: 38925119; PMCID: PMC11339621.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    19. Calibrated prediction intervals for polygenic scores across diverse contexts. Nat Genet. 2024 Jul; 56(7):1386-1396. Hou K, Xu Z, Ding Y, Mandla R, Shi Z, Boulier K, Harpak A, Pasaniuc B. PMID: 38886587; PMCID: PMC11465192.
      View in: PubMed   Mentions: 16     Fields:    Translation:Humans
    20. Cross-ancestry atlas of gene, isoform, and splicing regulation in the developing human brain. Science. 2024 05 24; 384(6698):eadh0829. Wen C, Margolis M, Dai R, Zhang P, Przytycki PF, Vo DD, Bhattacharya A, Matoba N, Tang M, Jiao C, Kim M, Tsai E, Hoh C, Aygün N, Walker RL, Chatzinakos C, Clarke D, Pratt H, PsychENCODE Consortium†, Peters MA, Gerstein M, Daskalakis NP, Weng Z, Jaffe AE, Kleinman JE, Hyde TM, Weinberger DR, Bray NJ, Sestan N, Geschwind DH, Roeder K, Gusev A, Pasaniuc B, Stein JL, Love MI, Pollard KS, Liu C, Gandal MJ, PsychENCODE Consortium. PMID: 38781368.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansCells
    21. Developmental isoform diversity in the human neocortex informs neuropsychiatric risk mechanisms. Science. 2024 05 24; 384(6698):eadh7688. Patowary A, Zhang P, Jops C, Vuong CK, Ge X, Hou K, Kim M, Gong N, Margolis M, Vo D, Wang X, Liu C, Pasaniuc B, Li JJ, Gandal MJ, de la Torre-Ubieta L. PMID: 38781356; PMCID: PMC11960787.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansCells
    22. Brain cell-type shifts in Alzheimer's disease, autism, and schizophrenia interrogated using methylomics and genetics. Sci Adv. 2024 May 24; 10(21):eadn7655. Yap CX, Vo DD, Heffel MG, Bhattacharya A, Wen C, Yang Y, Kemper KE, Zeng J, Zheng Z, Zhu Z, Hannon E, Vellame DS, Franklin A, Caggiano C, Wamsley B, Geschwind DH, Zaitlen N, Gusev A, Pasaniuc B, Mill J, Luo C, Gandal MJ. PMID: 38781333; PMCID: PMC11114225.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
    23. Generalizability of PGS313 for breast cancer risk in a Los Angeles biobank. HGG Adv. 2024 Jul 18; 5(3):100302. Shang H, Ding Y, Venkateswaran V, Boulier K, Kathuria-Prakash N, Malidarreh PB, Luber JM, Pasaniuc B. PMID: 38704641; PMCID: PMC11137525.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    24. Electronic health record signatures identify undiagnosed patients with common variable immunodeficiency disease. Sci Transl Med. 2024 May; 16(745):eade4510. Johnson R, Stephens AV, Mester R, Knyazev S, Kohn LA, Freund MK, Bondhus L, Hill BL, Schwarz T, Zaitlen N, Arboleda VA, A Bastarache L, Pasaniuc B, Butte MJ. PMID: 38691621; PMCID: PMC11402387.
      View in: PubMed   Mentions: 3     Fields:    
    25. Admix-kit: an integrated toolkit and pipeline for genetic analyses of admixed populations. Bioinformatics. 2024 03 29; 40(4). Hou K, Gogarten S, Kim J, Hua X, Dias JA, Sun Q, Wang Y, Tan T, Polygenic Risk Methods in Diverse Populations (PRIMED) Consortium Methods Working Group, Atkinson EG, Martin A, Shortt J, Hirbo J, Li Y, Pasaniuc B, Zhang H. PMID: 38490256; PMCID: PMC10980565.
      View in: PubMed   Mentions: 3     Fields:    
    26. Improving genetic risk modeling of dementia from real-world data in underrepresented populations. Res Sq. 2024 Feb 15. Chang T, Fu M, Valiente-Banuet L, Wadhwa S, Pasaniuc B, Vossel K. PMID: 38410460; PMCID: PMC10896371.
      View in: PubMed   Mentions:
    27. Improving genetic risk modeling of dementia from real-world data in underrepresented populations. medRxiv. 2024 Feb 06. Fu M, Valiente-Banuet L, Wadhwa SS, UCLA Precision Health Data Discovery Repository Working Group, UCLA Precision Health ATLAS Working Group, Pasaniuc B, Vossel K, Chang TS. PMID: 38370649; PMCID: PMC10871463.
      View in: PubMed   Mentions:
    28. Multi-class Modeling Identifies Shared Genetic Risk for Late-onset Epilepsy and Alzheimer's Disease. medRxiv. 2024 Feb 06. Fu M, Tran T, Eskin E, Lajonchere C, Pasaniuc B, Geschwind DH, Vossel K, Chang TS. PMID: 38370677; PMCID: PMC10871371.
      View in: PubMed   Mentions:
    29. Cell-type deconvolution of bulk-blood RNA-seq reveals biological insights into neuropsychiatric disorders. Am J Hum Genet. 2024 02 01; 111(2):323-337. Boltz T, Schwarz T, Bot M, Hou K, Caggiano C, Lapinska S, Duan C, Boks MP, Kahn RS, Zaitlen N, Pasaniuc B, Ophoff R. PMID: 38306997; PMCID: PMC10870131.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    30. Polygenic scores for tobacco use provide insights into systemic health risks in a diverse EHR-linked biobank in Los Angeles. Transl Psychiatry. 2024 Jan 18; 14(1):38. Venkateswaran V, Boulier K, Ding Y, Johnson R, Bhattacharya A, Pasaniuc B. PMID: 38238290; PMCID: PMC10796315.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    31. Multi-ancestry polygenic risk scores for venous thromboembolism. medRxiv. 2024 Jan 10. Jee YH, Thibord F, Dominguez A, Sept C, Boulier K, Venkateswaran V, Ding Y, Cherlin T, Verma SS, Faro VL, Bartz TM, Boland A, Brody JA, Deleuze JF, Emmerich J, Germain M, Johnson AD, Kooperberg C, Morange PE, Pankratz N, Psaty BM, Reiner AP, Smadja DM, Sitlani CM, Suchon P, Tang W, Trégouët DA, Zöllner S, Pasaniuc B, Damrauer SM, Sanna S, Snieder H, Lifelines Cohort Study, Kabrhel C, Smith NL, Kraft P, INVENT Consortium. PMID: 38260294; PMCID: PMC10802635.
      View in: PubMed   Mentions:
    32. Session Introduction: Overcoming health disparities in precision medicine. Pac Symp Biocomput. 2024; 29:322-326. De La Vega FM, Barnes KC, Fox K, Ioannidis A, Kenny E, Mathias RA, Pasaniuc B. PMID: 38160289.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    33. Isoform-level transcriptome-wide association uncovers genetic risk mechanisms for neuropsychiatric disorders in the human brain. Nat Genet. 2023 Dec; 55(12):2117-2128. Bhattacharya A, Vo DD, Jops C, Kim M, Wen C, Hervoso JL, Pasaniuc B, Gandal MJ. PMID: 38036788; PMCID: PMC10703692.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansCells
    34. Inferring disease architecture and predictive ability with LDpred2-auto. Am J Hum Genet. 2023 12 07; 110(12):2042-2055. Privé F, Albiñana C, Arbel J, Pasaniuc B, Vilhjálmsson BJ. PMID: 37944514; PMCID: PMC10716363.
      View in: PubMed   Mentions: 12     Fields:    Translation:Humans
    35. Interplay Of Serum Bilirubin and Tobacco Smoking with Lung and Head and Neck Cancers in a Diverse, EHR-linked Los Angeles Biobank. Res Sq. 2023 Oct 24. Venkateswaran V, Petter E, Boulier K, Ding Y, Bhattacharya A, Pasaniuc B. PMID: 37961486; PMCID: PMC10635352.
      View in: PubMed   Mentions:
    36. Developmental isoform diversity in the human neocortex informs neuropsychiatric risk mechanisms. bioRxiv. 2023 Oct 11. Patowary A, Zhang P, Jops C, Vuong CK, Ge X, Hou K, Kim M, Gong N, Margolis M, Vo D, Wang X, Liu C, Pasaniuc B, Li JJ, Gandal MJ, de la Torre-Ubieta L. PMID: 36993726; PMCID: PMC10055310.
      View in: PubMed   Mentions:
    37. Interplay Of Serum Bilirubin and Tobacco Smoking with Lung and Head and Neck Cancers in a Diverse, EHR-linked Los Angeles Biobank. medRxiv. 2023 Oct 03. Venkateswaran V, Petter E, Boulier K, Ding Y, Bhattacharya A, Pasaniuc B. PMID: 37873378; PMCID: PMC10592991.
      View in: PubMed   Mentions:
    38. Admix-kit: An Integrated Toolkit and Pipeline for Genetic Analyses of Admixed Populations. bioRxiv. 2023 Oct 02. Hou K, Gogarten S, Kim J, Hua X, Dias JA, Sun Q, Wang Y, Tan T, Polygenic Risk Methods in Diverse Populations (PRIMED) Consortium Methods Working Group, Atkinson EG, Martin A, Shortt J, Hirbo J, Li Y, Pasaniuc B, Zhang H. PMID: 37873338; PMCID: PMC10592849.
      View in: PubMed   Mentions:
    39. A second update on mapping the human genetic architecture of COVID-19. Nature. 2023 Sep; 621(7977):E7-E26. COVID-19 Host Genetics Initiative. PMID: 37674002; PMCID: PMC10482689.
      View in: PubMed   Mentions: 29     Fields:    Translation:Humans
    40. A Bayesian method for estimating gene-level polygenicity under the framework of transcriptome-wide association study. Stat Med. 2023 Nov 20; 42(26):4867-4885. Majumdar A, Pasaniuc B. PMID: 37643728.
      View in: PubMed   Mentions: 2     Fields:    
    41. Principles and methods for transferring polygenic risk scores across global populations. Nat Rev Genet. 2024 Jan; 25(1):8-25. Kachuri L, Chatterjee N, Hirbo J, Schaid DJ, Martin I, Kullo IJ, Kenny EE, Pasaniuc B, Polygenic Risk Methods in Diverse Populations (PRIMED) Consortium Methods Working Group, Witte JS, Ge T. PMID: 37620596; PMCID: PMC10961971.
      View in: PubMed   Mentions: 64     Fields:    Translation:Humans
    42. Calibrated prediction intervals for polygenic scores across diverse contexts. medRxiv. 2023 Jul 27. Hou K, Xu Z, Ding Y, Harpak A, Pasaniuc B. PMID: 37546999; PMCID: PMC10402211.
      View in: PubMed   Mentions:
    43. Genotype error due to low-coverage sequencing induces uncertainty in polygenic scoring. Am J Hum Genet. 2023 08 03; 110(8):1319-1329. Petter E, Ding Y, Hou K, Bhattacharya A, Gusev A, Zaitlen N, Pasaniuc B. PMID: 37490908; PMCID: PMC10432141.
      View in: PubMed   Mentions: 1     Fields:    
    44. Disease risk and healthcare utilization among ancestrally diverse groups in the Los Angeles region. Nat Med. 2023 07; 29(7):1845-1856. Caggiano C, Boudaie A, Shemirani R, Mefford J, Petter E, Chiu A, Ercelen D, He R, Tward D, Paul KC, Chang TS, Pasaniuc B, Kenny EE, Shortt JA, Gignoux CR, Balliu B, Arboleda VA, Belbin G, Zaitlen N. PMID: 37464048; PMCID: PMC11121511.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    45. Genome-wide analyses characterize shared heritability among cancers and identify novel cancer susceptibility regions. J Natl Cancer Inst. 2023 06 08; 115(6):712-732. Lindström S, Wang L, Feng H, Majumdar A, Huo S, Macdonald J, Harrison T, Turman C, Chen H, Mancuso N, Bammler T, Breast Cancer Association Consortium (BCAC), Gallinger S, Gruber SB, Gunter MJ, Le Marchand L, Moreno V, Offit K, Colorectal Transdisciplinary Study (CORECT), Colon Cancer Family Registry Study (CCFR), Genetics And, De Vivo I, O'Mara TA, Spurdle AB, Tomlinson I, Endometrial Cancer Association Consortium (ECAC), Fitzgerald R, Gharahkhani P, Gockel I, Jankowski J, Macgregor S, Schumacher J, Barnholtz-Sloan J, Bondy ML, Houlston RS, Jenkins RB, Melin B, Wrensch M, Brennan P, Christiani DC, Johansson M, Mckay J, Aldrich MC, Amos CI, Landi MT, Tardon A, International Lung Cancer Consortium (ILCCO), Bishop DT, Demenais F, Goldstein AM, Iles MM, Kanetsky PA, Law MH, Ovarian Cancer Association Consortium (OCAC), Amundadottir LT, Stolzenberg-Solomon R, Wolpin BM, Pancreatic Cancer Cohort Consortium (Panscan), Klein A, Petersen G, Risch H, Pancreatic Cancer Case-Control Consortium (Panc4), The PRACTICAL Consortium, Chanock SJ, Purdue MP, Scelo G, Pharoah P, Kar S, Hung RJ, Pasaniuc B, Kraft P. PMID: 36929942; PMCID: PMC10248849.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansCells
    46. Cell type deconvolution of bulk blood RNA-Seq to reveal biological insights of neuropsychiatric disorders. bioRxiv. 2023 May 25. Boltz T, Schwarz T, Bot M, Hou K, Caggiano C, Lapinska S, Duan C, Boks MP, Kahn RS, Zaitlen N, Pasaniuc B, Ophoff R. PMID: 37293101; PMCID: PMC10245943.
      View in: PubMed   Mentions:
    47. Impact of cross-ancestry genetic architecture on GWASs in admixed populations. Am J Hum Genet. 2023 06 01; 110(6):927-939. Mester R, Hou K, Ding Y, Meeks G, Burch KS, Bhattacharya A, Henn BM, Pasaniuc B. PMID: 37224807; PMCID: PMC10257009.
      View in: PubMed   Mentions: 12     Fields:    Translation:Humans
    48. Polygenic scoring accuracy varies across the genetic ancestry continuum. Nature. 2023 Jun; 618(7966):774-781. Ding Y, Hou K, Xu Z, Pimplaskar A, Petter E, Boulier K, Privé F, Vilhjálmsson BJ, Olde Loohuis LM, Pasaniuc B. PMID: 37198491; PMCID: PMC10284707.
      View in: PubMed   Mentions: 95     Fields:    Translation:Humans
    49. twas_sim, a Python-based tool for simulation and power analysis of transcriptome-wide association analysis. Bioinformatics. 2023 05 04; 39(5). Wang X, Lu Z, Bhattacharya A, Pasaniuc B, Mancuso N. PMID: 37099718; PMCID: PMC10172036.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
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    116. Large-scale transcriptome-wide association study identifies new prostate cancer risk regions. Nat Commun. 2018 10 04; 9(1):4079. Mancuso N, Gayther S, Gusev A, Zheng W, Penney KL, Kote-Jarai Z, Eeles R, Freedman M, Haiman C, Pasaniuc B, PRACTICAL consortium. PMID: 30287866; PMCID: PMC6172280.
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    117. Phenotype-Specific Enrichment of Mendelian Disorder Genes near GWAS Regions across 62 Complex Traits. Am J Hum Genet. 2018 10 04; 103(4):535-552. Freund MK, Burch KS, Shi H, Mancuso N, Kichaev G, Garske KM, Pan DZ, Miao Z, Mohlke KL, Laakso M, Pajukanta P, Pasaniuc B, Arboleda VA. PMID: 30290150; PMCID: PMC6174356.
      View in: PubMed   Mentions: 56     Fields:    Translation:HumansCells
    118. A Bayesian framework for multiple trait colocalization from summary association statistics. Bioinformatics. 2018 08 01; 34(15):2538-2545. Giambartolomei C, Zhenli Liu J, Zhang W, Hauberg M, Shi H, Boocock J, Pickrell J, Jaffe AE, CommonMind Consortium, Pasaniuc B, Roussos P. PMID: 29579179; PMCID: PMC6061859.
      View in: PubMed   Mentions: 154     Fields:    Translation:HumansCells
    119. A unifying framework for joint trait analysis under a non-infinitesimal model. Bioinformatics. 2018 07 01; 34(13):i195-i201. Johnson R, Shi H, Pasaniuc B, Sankararaman S. PMID: 29949958; PMCID: PMC6022541.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    120. Transcriptome-wide association studies accounting for colocalization using Egger regression. Genet Epidemiol. 2018 07; 42(5):418-433. Barfield R, Feng H, Gusev A, Wu L, Zheng W, Pasaniuc B, Kraft P. PMID: 29808603; PMCID: PMC6342197.
      View in: PubMed   Mentions: 48     Fields:    Translation:HumansCells
    121. Transcriptome-wide association study of schizophrenia and chromatin activity yields mechanistic disease insights. Nat Genet. 2018 04; 50(4):538-548. Gusev A, Mancuso N, Won H, Kousi M, Finucane HK, Reshef Y, Song L, Safi A, Schizophrenia Working Group of the Psychiatric Genomics Consortium, McCarroll S, Neale BM, Ophoff RA, O'Donovan MC, Crawford GE, Geschwind DH, Katsanis N, Sullivan PF, Pasaniuc B, Price AL. PMID: 29632383; PMCID: PMC5942893.
      View in: PubMed   Mentions: 238     Fields:    Translation:HumansAnimalsCells
    122. Methods for fine-mapping with chromatin and expression data. PLoS Genet. 2018 02; 14(2):e1007240. Roytman M, Kichaev G, Gusev A, Pasaniuc B. PMID: 29481575; PMCID: PMC5843356.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    123. Local Genetic Correlation Gives Insights into the Shared Genetic Architecture of Complex Traits. Am J Hum Genet. 2017 Nov 02; 101(5):737-751. Shi H, Mancuso N, Spendlove S, Pasaniuc B. PMID: 29100087; PMCID: PMC5673668.
      View in: PubMed   Mentions: 151     Fields:    Translation:Humans
    124. Erratum to: A multi-stage genome-wide association study of uterine fibroids in African Americans. Hum Genet. 2017 11; 136(11-12):1497-1498. Hellwege JN, Jeff JM, Wise LA, Gallagher CS, Wellons M, Hartmann KE, Jones SF, Torstenson ES, Dickinson S, Ruiz-Narváez EA, Rohland N, Allen A, Reich D, Tandon A, Pasaniuc B, Mancuso N, Im HK, Hinds DA, Palmer JR, Rosenberg L, Denny JC, Roden DM, Stewart EA, Morton CC, Kenny EE, Edwards TL, Velez Edwards DR. PMID: 28975356; PMCID: PMC5909202.
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    125. A multi-stage genome-wide association study of uterine fibroids in African Americans. Hum Genet. 2017 10; 136(10):1363-1373. Hellwege JN, Jeff JM, Wise LA, Gallagher CS, Wellons M, Hartmann KE, Jones SF, Torstenson ES, Dickinson S, Ruiz-Narváez EA, Rohland N, Allen A, Reich D, Tandon A, Pasaniuc B, Mancuso N, Im HK, Hinds DA, Palmer JR, Rosenberg L, Denny JC, Roden DM, Stewart EA, Morton CC, Kenny EE, Edwards TL, Velez Edwards DR. PMID: 28836065; PMCID: PMC5628188.
      View in: PubMed   Mentions: 29     Fields:    Translation:Humans
    126. Enhanced methods to detect haplotypic effects on gene expression. Bioinformatics. 2017 Aug 01; 33(15):2307-2313. Brown R, Kichaev G, Mancuso N, Boocock J, Pasaniuc B. PMID: 28369161; PMCID: PMC5860109.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    127. A Genetic Population Isolate in The Netherlands Showing Extensive Haplotype Sharing and Long Regions of Homozygosity. Genes (Basel). 2017 May 04; 8(5). Somers M, Olde Loohuis LM, Aukes MF, Pasaniuc B, de Visser KCL, Kahn RS, Sommer IE, Ophoff RA. PMID: 28471380; PMCID: PMC5448007.
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    128. Widespread Allelic Heterogeneity in Complex Traits. Am J Hum Genet. 2017 May 04; 100(5):789-802. Hormozdiari F, Zhu A, Kichaev G, Ju CJ, Segrè AV, Joo JWJ, Won H, Sankararaman S, Pasaniuc B, Shifman S, Eskin E. PMID: 28475861; PMCID: PMC5420356.
      View in: PubMed   Mentions: 50     Fields:    Translation:Humans
    129. Integrating Gene Expression with Summary Association Statistics to Identify Genes Associated with 30 Complex Traits. Am J Hum Genet. 2017 Mar 02; 100(3):473-487. Mancuso N, Shi H, Goddard P, Kichaev G, Gusev A, Pasaniuc B. PMID: 28238358; PMCID: PMC5339290.
      View in: PubMed   Mentions: 156     Fields:    Translation:HumansCells
    130. Fine-mapping of lipid regions in global populations discovers ethnic-specific signals and refines previously identified lipid loci. Hum Mol Genet. 2016 12 15; 25(24):5500-5512. Zubair N, Graff M, Luis Ambite J, Bush WS, Kichaev G, Lu Y, Manichaikul A, Sheu WH, Absher D, Assimes TL, Bielinski SJ, Bottinger EP, Buzkova P, Chuang LM, Chung RH, Cochran B, Dumitrescu L, Gottesman O, Haessler JW, Haiman C, Heiss G, Hsiung CA, Hung YJ, Hwu CM, Juang JJ, Le Marchand L, Lee IT, Lee WJ, Lin LA, Lin D, Lin SY, Mackey RH, Martin LW, Pasaniuc B, Peters U, Predazzi I, Quertermous T, Reiner AP, Robinson J, Rotter JI, Ryckman KK, Schreiner PJ, Stahl E, Tao R, Tsai MY, Waite LL, Wang TD, Buyske S, Ida Chen YD, Cheng I, Crawford DC, Loos RJF, Rich SS, Fornage M, North KE, Kooperberg C, Carty CL. PMID: 28426890; PMCID: PMC5721937.
      View in: PubMed   Mentions: 19     Fields:    Translation:Humans
    131. Colocalization of GWAS and eQTL Signals Detects Target Genes. Am J Hum Genet. 2016 Dec 01; 99(6):1245-1260. Hormozdiari F, van de Bunt M, Segrè AV, Li X, Joo JWJ, Bilow M, Sul JH, Sankararaman S, Pasaniuc B, Eskin E. PMID: 27866706; PMCID: PMC5142122.
      View in: PubMed   Mentions: 383     Fields:    Translation:Humans
    132. Dissecting the genetics of complex traits using summary association statistics. Nat Rev Genet. 2017 02; 18(2):117-127. Pasaniuc B, Price AL. PMID: 27840428; PMCID: PMC5449190.
      View in: PubMed   Mentions: 213     Fields:    Translation:Humans
    133. Improved methods for multi-trait fine mapping of pleiotropic risk loci. Bioinformatics. 2017 01 15; 33(2):248-255. Kichaev G, Roytman M, Johnson R, Eskin E, Lindström S, Kraft P, Pasaniuc B. PMID: 27663501; PMCID: PMC5254076.
      View in: PubMed   Mentions: 73     Fields:    Translation:Humans
    134. Contrasting the Genetic Architecture of 30 Complex Traits from Summary Association Data. Am J Hum Genet. 2016 07 07; 99(1):139-53. Shi H, Kichaev G, Pasaniuc B. PMID: 27346688; PMCID: PMC5005444.
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    135. Atlas of prostate cancer heritability in European and African-American men pinpoints tissue-specific regulation. Nat Commun. 2016 Apr 07; 7:10979. Gusev A, Shi H, Kichaev G, Pomerantz M, Li F, Long HW, Ingles SA, Kittles RA, Strom SS, Rybicki BA, Nemesure B, Isaacs WB, Zheng W, Pettaway CA, Yeboah ED, Tettey Y, Biritwum RB, Adjei AA, Tay E, Truelove A, Niwa S, Chokkalingam AP, John EM, Murphy AB, Signorello LB, Carpten J, Leske MC, Wu SY, Hennis AJ, Neslund-Dudas C, Hsing AW, Chu L, Goodman PJ, Klein EA, Witte JS, Casey G, Kaggwa S, Cook MB, Stram DO, Blot WJ, Eeles RA, Easton D, Kote-Jarai Z, Al Olama AA, Benlloch S, Muir K, Giles GG, Southey MC, Fitzgerald LM, Gronberg H, Wiklund F, Aly M, Henderson BE, Schleutker J, Wahlfors T, Tammela TL, Nordestgaard BG, Key TJ, Travis RC, Neal DE, Donovan JL, Hamdy FC, Pharoah P, Pashayan N, Khaw KT, Stanford JL, Thibodeau SN, McDonnell SK, Schaid DJ, Maier C, Vogel W, Luedeke M, Herkommer K, Kibel AS, Cybulski C, Wokolorczyk D, Kluzniak W, Cannon-Albright L, Teerlink C, Brenner H, Dieffenbach AK, Arndt V, Park JY, Sellers TA, Lin HY, Slavov C, Kaneva R, Mitev V, Batra J, Spurdle A, Clements JA, Teixeira MR, Pandha H, Michael A, Paulo P, Maia S, Kierzek A, PRACTICAL consortium, Conti DV, Albanes D, Berg C, Berndt SI, Campa D, Crawford ED, Diver WR, Gapstur SM, Gaziano JM, Giovannucci E, Hoover R, Hunter DJ, Johansson M, Kraft P, Le Marchand L, Lindström S, Navarro C, Overvad K, Riboli E, Siddiq A, Stevens VL, Trichopoulos D, Vineis P, Yeager M, Trynka G, Raychaudhuri S, Schumacher FR, Price AL, Freedman ML, Haiman CA, Pasaniuc B. PMID: 27052111; PMCID: PMC4829663.
      View in: PubMed   Mentions: 34     Fields:    Translation:HumansCells
    136. Integrative approaches for large-scale transcriptome-wide association studies. Nat Genet. 2016 Mar; 48(3):245-52. Gusev A, Ko A, Shi H, Bhatia G, Chung W, Penninx BW, Jansen R, de Geus EJ, Boomsma DI, Wright FA, Sullivan PF, Nikkola E, Alvarez M, Civelek M, Lusis AJ, Lehtimäki T, Raitoharju E, Kähönen M, Seppälä I, Raitakari OT, Kuusisto J, Laakso M, Price AL, Pajukanta P, Pasaniuc B. PMID: 26854917; PMCID: PMC4767558.
      View in: PubMed   Mentions: 1136     Fields:    Translation:HumansAnimalsCells
    137. Prostate Cancer Susceptibility in Men of African Ancestry at 8q24. J Natl Cancer Inst. 2016 Jul; 108(7). Han Y, Rand KA, Hazelett DJ, Ingles SA, Kittles RA, Strom SS, Rybicki BA, Nemesure B, Isaacs WB, Stanford JL, Zheng W, Schumacher FR, Berndt SI, Wang Z, Xu J, Rohland N, Reich D, Tandon A, Pasaniuc B, Allen A, Quinque D, Mallick S, Notani D, Rosenfeld MG, Jayani RS, Kolb S, Gapstur SM, Stevens VL, Pettaway CA, Yeboah ED, Tettey Y, Biritwum RB, Adjei AA, Tay E, Truelove A, Niwa S, Chokkalingam AP, John EM, Murphy AB, Signorello LB, Carpten J, Leske MC, Wu SY, Hennis AJM, Neslund-Dudas C, Hsing AW, Chu L, Goodman PJ, Klein EA, Zheng SL, Witte JS, Casey G, Lubwama A, Pooler LC, Sheng X, Coetzee GA, Cook MB, Chanock SJ, Stram DO, Watya S, Blot WJ, Conti DV, Henderson BE, Haiman CA. PMID: 26823525; PMCID: PMC4948565.
      View in: PubMed   Mentions: 79     Fields:    Translation:HumansCells
    138. Whole-exome sequencing of over 4100 men of African ancestry and prostate cancer risk. Hum Mol Genet. 2016 Jan 15; 25(2):371-81. Rand KA, Rohland N, Tandon A, Stram A, Sheng X, Do R, Pasaniuc B, Allen A, Quinque D, Mallick S, Le Marchand L, Kaggwa S, Lubwama A, African Ancestry Prostate Cancer GWAS Consortium, ELLIPSE/GAME-ON Consortium, Stram DO, Watya S, Henderson BE, Conti DV, Reich D, Haiman CA. PMID: 26604137; PMCID: PMC4865031.
      View in: PubMed   Mentions: 20     Fields:    Translation:Humans
    139. The contribution of rare variation to prostate cancer heritability. Nat Genet. 2016 Jan; 48(1):30-5. Mancuso N, Rohland N, Rand KA, Tandon A, Allen A, Quinque D, Mallick S, Li H, Stram A, Sheng X, Kote-Jarai Z, Easton DF, Eeles RA, PRACTICAL consortium, Le Marchand L, Lubwama A, Stram D, Watya S, Conti DV, Henderson B, Haiman CA, Pasaniuc B, Reich D. PMID: 26569126; PMCID: PMC7534691.
      View in: PubMed   Mentions: 80     Fields:    Translation:Humans
    140. Leveraging local ancestry to detect gene-gene interactions in genome-wide data. BMC Genet. 2015 Oct 24; 16:124. Aschard H, Gusev A, Brown R, Pasaniuc B. PMID: 26498930; PMCID: PMC4619349.
      View in: PubMed   Mentions: 11     Fields:    Translation:Humans
    141. Modeling Linkage Disequilibrium Increases Accuracy of Polygenic Risk Scores. Am J Hum Genet. 2015 Oct 01; 97(4):576-92. Vilhjálmsson BJ, Yang J, Finucane HK, Gusev A, Lindström S, Ripke S, Genovese G, Loh PR, Bhatia G, Do R, Hayeck T, Won HH, Schizophrenia Working Group of the Psychiatric Genomics Consortium, Discovery, Biology, and Risk of , Kathiresan S, Pato M, Pato C, Tamimi R, Stahl E, Zaitlen N, Pasaniuc B, Belbin G, Kenny EE, Schierup MH, De Jager P, Patsopoulos NA, McCarroll S, Daly M, Purcell S, Chasman D, Neale B, Goddard M, Visscher PM, Kraft P, Patterson N, Price AL. PMID: 26430803; PMCID: PMC4596916.
      View in: PubMed   Mentions: 660     Fields:    Translation:Humans
    142. Leveraging Functional-Annotation Data in Trans-ethnic Fine-Mapping Studies. Am J Hum Genet. 2015 Aug 06; 97(2):260-71. Kichaev G, Pasaniuc B. PMID: 26189819; PMCID: PMC4573268.
      View in: PubMed   Mentions: 118     Fields:    Translation:Humans
    143. A multivariate Bernoulli model to predict DNaseI hypersensitivity status from haplotype data. Bioinformatics. 2015 Nov 01; 31(21):3514-21. Shi H, Pasaniuc B, Lange KL. PMID: 26139633; PMCID: PMC4836401.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    144. Identification of causal genes for complex traits. Bioinformatics. 2015 Jun 15; 31(12):i206-13. Hormozdiari F, Kichaev G, Yang WY, Pasaniuc B, Eskin E. PMID: 26072484; PMCID: PMC4542778.
      View in: PubMed   Mentions: 43     Fields:    Translation:HumansAnimals
    145. Leveraging ancestry to improve causal variant identification in exome sequencing for monogenic disorders. Eur J Hum Genet. 2016 Jan; 24(1):113-9. Brown R, Lee H, Eskin A, Kichaev G, Lohmueller KE, Reversade B, Nelson SF, Pasaniuc B. PMID: 25898925; PMCID: PMC4795218.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    146. A spatial haplotype copying model with applications to genotype imputation. J Comput Biol. 2015 May; 22(5):451-62. Yang WY, Hormozdiari F, Eskin E, Pasaniuc B. PMID: 25526526; PMCID: PMC4425418.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    147. Leveraging population admixture to characterize the heritability of complex traits. Nat Genet. 2014 Dec; 46(12):1356-62. Zaitlen N, Pasaniuc B, Sankararaman S, Bhatia G, Zhang J, Gusev A, Young T, Tandon A, Pollack S, Vilhjálmsson BJ, Assimes TL, Berndt SI, Blot WJ, Chanock S, Franceschini N, Goodman PG, He J, Hennis AJ, Hsing A, Ingles SA, Isaacs W, Kittles RA, Klein EA, Lange LA, Nemesure B, Patterson N, Reich D, Rybicki BA, Stanford JL, Stevens VL, Strom SS, Whitsel EA, Witte JS, Xu J, Haiman C, Wilson JG, Kooperberg C, Stram D, Reiner AP, Tang H, Price AL. PMID: 25383972; PMCID: PMC4244251.
      View in: PubMed   Mentions: 44     Fields:    Translation:Humans
    148. Partitioning heritability of regulatory and cell-type-specific variants across 11 common diseases. Am J Hum Genet. 2014 Nov 06; 95(5):535-52. Gusev A, Lee SH, Trynka G, Finucane H, Vilhjálmsson BJ, Xu H, Zang C, Ripke S, Bulik-Sullivan B, Stahl E, Schizophrenia Working Group of the Psychiatric Genomics Consortium, SWE-SCZ Consortium, Kähler AK, Hultman CM, Purcell SM, McCarroll SA, Daly M, Pasaniuc B, Sullivan PF, Neale BM, Wray NR, Raychaudhuri S, Price AL, Schizophrenia Working Group of the Psychiatric Genomics Consortium, SWE-SCZ Consortium. PMID: 25439723; PMCID: PMC4225595.
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    149. Spatial localization of recent ancestors for admixed individuals. G3 (Bethesda). 2014 Nov 03; 4(12):2505-18. Yang WY, Platt A, Chiang CW, Eskin E, Novembre J, Pasaniuc B. PMID: 25371484; PMCID: PMC4267945.
      View in: PubMed   Mentions: 10     Fields:    Translation:Humans
    150. Integrating functional data to prioritize causal variants in statistical fine-mapping studies. PLoS Genet. 2014 Oct; 10(10):e1004722. Kichaev G, Yang WY, Lindstrom S, Hormozdiari F, Eskin E, Price AL, Kraft P, Pasaniuc B. PMID: 25357204; PMCID: PMC4214605.
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    151. Identifying causal variants at loci with multiple signals of association. Genetics. 2014 Oct; 198(2):497-508. Hormozdiari F, Kostem E, Kang EY, Pasaniuc B, Eskin E. PMID: 25104515; PMCID: PMC4196608.
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    152. Fast and accurate imputation of summary statistics enhances evidence of functional enrichment. Bioinformatics. 2014 Oct 15; 30(20):2906-14. Pasaniuc B, Zaitlen N, Shi H, Bhatia G, Gusev A, Pickrell J, Hirschhorn J, Strachan DP, Patterson N, Price AL. PMID: 24990607; PMCID: PMC4184260.
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    153. Amerindian-specific regions under positive selection harbour new lipid variants in Latinos. Nat Commun. 2014 Jun 02; 5:3983. Ko A, Cantor RM, Weissglas-Volkov D, Nikkola E, Reddy PM, Sinsheimer JS, Pasaniuc B, Brown R, Alvarez M, Rodriguez A, Rodriguez-Guillen R, Bautista IC, Arellano-Campos O, Muñoz-Hernández LL, Salomaa V, Kaprio J, Jula A, Jauhiainen M, Heliövaara M, Raitakari O, Lehtimäki T, Eriksson JG, Perola M, Lohmueller KE, Matikainen N, Taskinen MR, Rodriguez-Torres M, Riba L, Tusie-Luna T, Aguilar-Salinas CA, Pajukanta P. PMID: 24886709; PMCID: PMC4062071.
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    154. Enhanced methods for local ancestry assignment in sequenced admixed individuals. PLoS Comput Biol. 2014 Apr; 10(4):e1003555. Brown R, Pasaniuc B. PMID: 24743331; PMCID: PMC3990492.
      View in: PubMed   Mentions: 18     Fields:    Translation:Humans
    155. IBD genetics: focus on (dys) regulation in immune cells and the epithelium. Gastroenterology. 2014 Apr; 146(4):896-9. Kaser A, Pasaniuc B. PMID: 24566108.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimalsCells
    156. Quantifying missing heritability at known GWAS loci. PLoS Genet. 2013; 9(12):e1003993. Gusev A, Bhatia G, Zaitlen N, Vilhjalmsson BJ, Diogo D, Stahl EA, Gregersen PK, Worthington J, Klareskog L, Raychaudhuri S, Plenge RM, Pasaniuc B, Price AL. PMID: 24385918; PMCID: PMC3873246.
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    157. Leveraging reads that span multiple single nucleotide polymorphisms for haplotype inference from sequencing data. Bioinformatics. 2013 Sep 15; 29(18):2245-52. Yang WY, Hormozdiari F, Wang Z, He D, Pasaniuc B, Eskin E. PMID: 23825370; PMCID: PMC3753566.
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    158. Using extended genealogy to estimate components of heritability for 23 quantitative and dichotomous traits. PLoS Genet. 2013 May; 9(5):e1003520. Zaitlen N, Kraft P, Patterson N, Pasaniuc B, Bhatia G, Pollack S, Price AL. PMID: 23737753; PMCID: PMC3667752.
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    159. Enhanced localization of genetic samples through linkage-disequilibrium correction. Am J Hum Genet. 2013 Jun 06; 92(6):882-94. Baran Y, Quintela I, Carracedo A, Pasaniuc B, Halperin E. PMID: 23726367; PMCID: PMC3675263.
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    160. Analysis of Latino populations from GALA and MEC studies reveals genomic loci with biased local ancestry estimation. Bioinformatics. 2013 Jun 01; 29(11):1407-15. Pasaniuc B, Sankararaman S, Torgerson DG, Gignoux C, Zaitlen N, Eng C, Rodriguez-Cintron W, Chapela R, Ford JG, Avila PC, Rodriguez-Santana J, Chen GK, Le Marchand L, Henderson B, Reich D, Haiman CA, Gonzàlez Burchard E, Halperin E. PMID: 23572411; PMCID: PMC3661056.
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    161. Using population admixture to help complete maps of the human genome. Nat Genet. 2013 Apr; 45(4):406-14, 414e1-2. Genovese G, Handsaker RE, Li H, Altemose N, Lindgren AM, Chambert K, Pasaniuc B, Price AL, Reich D, Morton CC, Pollak MR, Wilson JG, McCarroll SA. PMID: 23435088; PMCID: PMC3683849.
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    162. Informed conditioning on clinical covariates increases power in case-control association studies. PLoS Genet. 2012; 8(11):e1003032. Zaitlen N, Lindström S, Pasaniuc B, Cornelis M, Genovese G, Pollack S, Barton A, Bickeböller H, Bowden DW, Eyre S, Freedman BI, Friedman DJ, Field JK, Groop L, Haugen A, Heinrich J, Henderson BE, Hicks PJ, Hocking LJ, Kolonel LN, Landi MT, Langefeld CD, Le Marchand L, Meister M, Morgan AW, Raji OY, Risch A, Rosenberger A, Scherf D, Steer S, Walshaw M, Waters KM, Wilson AG, Wordsworth P, Zienolddiny S, Tchetgen ET, Haiman C, Hunter DJ, Plenge RM, Worthington J, Christiani DC, Schaumberg DA, Chasman DI, Altshuler D, Voight B, Kraft P, Patterson N, Price AL. PMID: 23144628; PMCID: PMC3493452.
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    163. Extremely low-coverage sequencing and imputation increases power for genome-wide association studies. Nat Genet. 2012 May 20; 44(6):631-5. Pasaniuc B, Rohland N, McLaren PJ, Garimella K, Zaitlen N, Li H, Gupta N, Neale BM, Daly MJ, Sklar P, Sullivan PF, Bergen S, Moran JL, Hultman CM, Lichtenstein P, Magnusson P, Purcell SM, Haas DW, Liang L, Sunyaev S, Patterson N, de Bakker PI, Reich D, Price AL. PMID: 22610117; PMCID: PMC3400344.
      View in: PubMed   Mentions: 147     Fields:    Translation:Humans
    164. Analysis of case-control association studies with known risk variants. Bioinformatics. 2012 Jul 01; 28(13):1729-37. Zaitlen N, Pasaniuc B, Patterson N, Pollack S, Voight B, Groop L, Altshuler D, Henderson BE, Kolonel LN, Le Marchand L, Waters K, Haiman CA, Stranger BE, Dermitzakis ET, Kraft P, Price AL. PMID: 22556366; PMCID: PMC3381970.
      View in: PubMed   Mentions: 20     Fields:    Translation:Humans
    165. Fast and accurate inference of local ancestry in Latino populations. Bioinformatics. 2012 May 15; 28(10):1359-67. Baran Y, Pasaniuc B, Sankararaman S, Torgerson DG, Gignoux C, Eng C, Rodriguez-Cintron W, Chapela R, Ford JG, Avila PC, Rodriguez-Santana J, Burchard EG, Halperin E. PMID: 22495753; PMCID: PMC3348558.
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    166. Admixture mapping identifies a locus on 6q25 associated with breast cancer risk in US Latinas. Hum Mol Genet. 2012 Apr 15; 21(8):1907-17. Fejerman L, Chen GK, Eng C, Huntsman S, Hu D, Williams A, Pasaniuc B, John EM, Via M, Gignoux C, Ingles S, Monroe KR, Kolonel LN, Torres-Mejía G, Pérez-Stable EJ, Burchard EG, Henderson BE, Haiman CA, Ziv E. PMID: 22228098; PMCID: PMC3313799.
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    167. Combining effects from rare and common genetic variants in an exome-wide association study of sequence data. BMC Proc. 2011 Nov 29; 5 Suppl 9:S44. Aschard H, Qiu W, Pasaniuc B, Zaitlen N, Cho MH, Carey V. PMID: 22373328; PMCID: PMC3287881.
      View in: PubMed   Mentions: 2  
    168. Genome-wide comparison of African-ancestry populations from CARe and other cohorts reveals signals of natural selection. Am J Hum Genet. 2011 Sep 09; 89(3):368-81. Bhatia G, Patterson N, Pasaniuc B, Zaitlen N, Genovese G, Pollack S, Mallick S, Myers S, Tandon A, Spencer C, Palmer CD, Adeyemo AA, Akylbekova EL, Cupples LA, Divers J, Fornage M, Kao WH, Lange L, Li M, Musani S, Mychaleckyj JC, Ogunniyi A, Papanicolaou G, Rotimi CN, Rotter JI, Ruczinski I, Salako B, Siscovick DS, Tayo BO, Yang Q, McCarroll S, Sabeti P, Lettre G, De Jager P, Hirschhorn J, Zhu X, Cooper R, Reich D, Wilson JG, Price AL. PMID: 21907010; PMCID: PMC3169818.
      View in: PubMed   Mentions: 52     Fields:    Translation:Humans
    169. Inhibition of activated pericentromeric SINE/Alu repeat transcription in senescent human adult stem cells reinstates self-renewal. Cell Cycle. 2011 Sep 01; 10(17):3016-30. Wang J, Geesman GJ, Hostikka SL, Atallah M, Blackwell B, Lee E, Cook PJ, Pasaniuc B, Shariat G, Halperin E, Dobke M, Rosenfeld MG, Jordan IK, Lunyak VV. PMID: 21862875; PMCID: PMC3218602.
      View in: PubMed   Mentions: 67     Fields:    Translation:HumansCells
    170. Genotyping common and rare variation using overlapping pool sequencing. BMC Bioinformatics. 2011; 12 Suppl 6:S2. He D, Zaitlen N, Pasaniuc B, Eskin E, Halperin E. PMID: 21989232; PMCID: PMC3194190.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    171. New approaches to disease mapping in admixed populations. Nat Rev Genet. 2011 Jun 28; 12(8):523-8. Seldin MF, Pasaniuc B, Price AL. PMID: 21709689; PMCID: PMC3142784.
      View in: PubMed   Mentions: 108     Fields:    Translation:Humans
    172. Enhanced statistical tests for GWAS in admixed populations: assessment using African Americans from CARe and a Breast Cancer Consortium. PLoS Genet. 2011 Apr; 7(4):e1001371. Pasaniuc B, Zaitlen N, Lettre G, Chen GK, Tandon A, Kao WH, Ruczinski I, Fornage M, Siscovick DS, Zhu X, Larkin E, Lange LA, Cupples LA, Yang Q, Akylbekova EL, Musani SK, Divers J, Mychaleckyj J, Li M, Papanicolaou GJ, Millikan RC, Ambrosone CB, John EM, Bernstein L, Zheng W, Hu JJ, Ziegler RG, Nyante SJ, Bandera EV, Ingles SA, Press MF, Chanock SJ, Deming SL, Rodriguez-Gil JL, Palmer CD, Buxbaum S, Ekunwe L, Hirschhorn JN, Henderson BE, Myers S, Haiman CA, Reich D, Patterson N, Wilson JG, Price AL. PMID: 21541012; PMCID: PMC3080860.
      View in: PubMed   Mentions: 82     Fields:    Translation:Humans
    173. Accurate estimation of expression levels of homologous genes in RNA-seq experiments. J Comput Biol. 2011 Mar; 18(3):459-68. Pasaniuc B, Zaitlen N, Halperin E. PMID: 21385047.
      View in: PubMed   Mentions: 24     Fields:    Translation:Humans
    174. A generic coalescent-based framework for the selection of a reference panel for imputation. Genet Epidemiol. 2010 Dec; 34(8):773-82. Pasaniuc B, Avinery R, Gur T, Skibola CF, Bracci PM, Halperin E. PMID: 21058333; PMCID: PMC3876740.
      View in: PubMed   Mentions: 18     Fields:    Translation:Humans
    175. Leveraging genetic variability across populations for the identification of causal variants. Am J Hum Genet. 2010 Jan; 86(1):23-33. Zaitlen N, Pasaniuc B, Gur T, Ziv E, Halperin E. PMID: 20085711; PMCID: PMC2801753.
      View in: PubMed   Mentions: 96     Fields:    Translation:Humans
    176. Inference of locus-specific ancestry in closely related populations. Bioinformatics. 2009 Jun 15; 25(12):i213-21. Pasaniuc B, Sankararaman S, Kimmel G, Halperin E. PMID: 19477991; PMCID: PMC2687951.
      View in: PubMed   Mentions: 88     Fields:    Translation:Humans
    177. Genotype error detection using Hidden Markov Models of haplotype diversity. J Comput Biol. 2008 Nov; 15(9):1155-71. Kennedy J, Mandoiu I, Pasaniuc B. PMID: 18973433.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
    178. Highly scalable genotype phasing by entropy minimization. IEEE/ACM Trans Comput Biol Bioinform. 2008 Apr-Jun; 5(2):252-61. Gusev A, Mandoiu II, Pasaniuc B. PMID: 18451434.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    179. Highly scalable genotype phasing by entropy minimization. Conf Proc IEEE Eng Med Biol Soc. 2006; 2006:3482-6. Pasaniuc B, Mandoiu I. PMID: 17946566.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
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