Bogdan Pasaniuc

Title(s)Department Vice Chair, Computational Medicine
SchoolMedicine
ORCID ORCID Icon0000-0002-0227-2056 Additional info
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    Other Positions
    Title(s)Professor, Pathology and Laboratory Medicine

    Title(s)Professor, Human Genetics

    Title(s)Professor, Computational Medicine


    Collapse Biography 
    Collapse Education and Training
    Harvard School of Public Health, MAPostdoctoral Fellow2012Statistical Genetics
    Broad Institute of Harvard and MIT, MAPostdoctoral Fellow2012Population and Medical Genetics
    ICSI, UC Berkeley, CAPostdoctoral Fellow2010Computational Biology
    University of Connecticut, CTPhD2008Computer Science and Bioinformatics
    A.I.Cuza University of Iasi , RomaniaBSc2003Computer Science

    Collapse Overview 
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    Dr Pasaniuc is an professor of Computational Medicine, Human Genetics and Pathology&Laboratory Medicine at UCLA. Dr Pasaniuc develops statistical and computational methods to understand the genetic basis of disease, focusing on under-represented populations, integrative genomics, and biobank studies. Dr Pasaniuc group developed machine learning methods to integrate epigenetic profiles within trans-ancestry studies to localize disease variants and genes; his group introduced transcriptome-wide association studies (TWAS) using predicted gene expression as a principled approach to identify disease genes for many traits such as Schizophrenia, Ovarian Cancer and Prostate Cancer. Dr Pasaniuc serves as Associate Director of Population Genetics of the Institute for Precision Health at UCLA that links the genetics of more than 150k patients with their electronic health record to predict health outcomes, to stratify patients based on their genetic risk to disease and to translate genomics to the clinic. Dr Pasaniuc also serves as PI for the Center for Admixed populations and Health Equity and for the Biomedical Data Science Training Program for Precision Health Equity at UCLA.
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    Collapse Research Activities and Funding
    PRS Center for Admixed Populations and Health Equity (CAPE)
    NIH U01HG011715Jun 8, 2021 - Mar 31, 2026
    Role: Principal Investigator
    Elucidation of the genetic mechanisms driving prostate tumorigenesis through integrative computational and functional approaches
    NIH R01CA251555Mar 2, 2021 - Feb 28, 2026
    Role: Co-Principal Investigator
    Collaborative multi-site project to speed the identification and management of rare genetic immune diseases
    NIH R01AI153827Feb 25, 2021 - Jan 31, 2026
    Role: Co-Principal Investigator
    Joint genomic and statistical analyses of schizophrenia and bipolar to decipher genetic susceptibility
    NIH R01MH115676Apr 1, 2018 - Jan 31, 2023
    Role: Co-Principal Investigator
    The Role of Splice Quantitative Traits in Ovarian Cancer Pathogenesis
    NIH R21CA220078Jun 15, 2017 - May 31, 2019
    Role: Co-Principal Investigator
    Integrative approaches for mapping the genetic risk of complex traits
    NIH R01HG009120Mar 1, 2017 - Feb 28, 2022
    Role: Principal Investigator
    Metrics and methods for cross-population fine mapping
    NIH R03CA162200Sep 12, 2012 - Aug 31, 2014
    Role: Principal Investigator

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    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Inferring disease architecture and predictive ability with LDpred2-auto. Am J Hum Genet. 2023 Nov 01. Privé F, Albiñana C, Arbel J, Pasaniuc B, Vilhjálmsson BJ. PMID: 37944514.
      View in: PubMed   Mentions:    Fields:    
    2. Developmental isoform diversity in the human neocortex informs neuropsychiatric risk mechanisms. bioRxiv. 2023 Oct 11. Patowary A, Zhang P, Jops C, Vuong CK, Ge X, Hou K, Kim M, Gong N, Margolis M, Vo D, Wang X, Liu C, Pasaniuc B, Li JJ, Gandal MJ, de la Torre-Ubieta L. PMID: 36993726; PMCID: PMC10055310.
      View in: PubMed   Mentions:
    3. Interplay Of Serum Bilirubin and Tobacco Smoking with Lung and Head and Neck Cancers in a Diverse, EHR-linked Los Angeles Biobank. medRxiv. 2023 Oct 03. Venkateswaran V, Petter E, Boulier K, Ding Y, Bhattacharya A, Pasaniuc B. PMID: 37873378; PMCID: PMC10592991.
      View in: PubMed   Mentions:
    4. Admix-kit: An Integrated Toolkit and Pipeline for Genetic Analyses of Admixed Populations. bioRxiv. 2023 Oct 02. Hou K, Gogarten S, Kim J, Hua X, Dias JA, Sun Q, Wang Y, Tan T, Polygenic Risk Methods in Diverse Populations (PRIMED) Consortium Methods Working Group, Atkinson EG, Martin A, Shortt J, Hirbo J, Li Y, Pasaniuc B, Zhang H. PMID: 37873338; PMCID: PMC10592849.
      View in: PubMed   Mentions:
    5. A second update on mapping the human genetic architecture of COVID-19. Nature. 2023 Sep; 621(7977):E7-E26. COVID-19 Host Genetics Initiative. PMID: 37674002; PMCID: PMC10482689.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    6. A Bayesian method for estimating gene-level polygenicity under the framework of transcriptome-wide association study. Stat Med. 2023 Nov 20; 42(26):4867-4885. Majumdar A, Pasaniuc B. PMID: 37643728.
      View in: PubMed   Mentions:    Fields:    
    7. Principles and methods for transferring polygenic risk scores across global populations. Nat Rev Genet. 2023 Aug 24. Kachuri L, Chatterjee N, Hirbo J, Schaid DJ, Martin I, Kullo IJ, Kenny EE, Pasaniuc B, Polygenic Risk Methods in Diverse Populations (PRIMED) Consortium Methods Working Group, Witte JS, Ge T. PMID: 37620596.
      View in: PubMed   Mentions: 1     Fields:    
    8. Calibrated prediction intervals for polygenic scores across diverse contexts. medRxiv. 2023 Jul 27. Hou K, Xu Z, Ding Y, Harpak A, Pasaniuc B. PMID: 37546999; PMCID: PMC10402211.
      View in: PubMed   Mentions:
    9. Genotype error due to low-coverage sequencing induces uncertainty in polygenic scoring. Am J Hum Genet. 2023 08 03; 110(8):1319-1329. Petter E, Ding Y, Hou K, Bhattacharya A, Gusev A, Zaitlen N, Pasaniuc B. PMID: 37490908; PMCID: PMC10432141.
      View in: PubMed   Mentions:    Fields:    
    10. Disease risk and healthcare utilization among ancestrally diverse groups in the Los Angeles region. Nat Med. 2023 07; 29(7):1845-1856. Caggiano C, Boudaie A, Shemirani R, Mefford J, Petter E, Chiu A, Ercelen D, He R, Tward D, Paul KC, Chang TS, Pasaniuc B, Kenny EE, Shortt JA, Gignoux CR, Balliu B, Arboleda VA, Belbin G, Zaitlen N. PMID: 37464048.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    11. Genome-wide analyses characterize shared heritability among cancers and identify novel cancer susceptibility regions. J Natl Cancer Inst. 2023 06 08; 115(6):712-732. Lindström S, Wang L, Feng H, Majumdar A, Huo S, Macdonald J, Harrison T, Turman C, Chen H, Mancuso N, Bammler T, Breast Cancer Association Consortium (BCAC), Gallinger S, Gruber SB, Gunter MJ, Le Marchand L, Moreno V, Offit K, Colorectal Transdisciplinary Study (CORECT), Colon Cancer Family Registry Study (CCFR), Genetics And, De Vivo I, O'Mara TA, Spurdle AB, Tomlinson I, Endometrial Cancer Association Consortium (ECAC), Fitzgerald R, Gharahkhani P, Gockel I, Jankowski J, Macgregor S, Schumacher J, Barnholtz-Sloan J, Bondy ML, Houlston RS, Jenkins RB, Melin B, Wrensch M, Brennan P, Christiani DC, Johansson M, Mckay J, Aldrich MC, Amos CI, Landi MT, Tardon A, International Lung Cancer Consortium (ILCCO), Bishop DT, Demenais F, Goldstein AM, Iles MM, Kanetsky PA, Law MH, Ovarian Cancer Association Consortium (OCAC), Amundadottir LT, Stolzenberg-Solomon R, Wolpin BM, Pancreatic Cancer Cohort Consortium (Panscan), Klein A, Petersen G, Risch H, Pancreatic Cancer Case-Control Consortium (Panc4), The PRACTICAL Consortium, Chanock SJ, Purdue MP, Scelo G, Pharoah P, Kar S, Hung RJ, Pasaniuc B, Kraft P. PMID: 36929942; PMCID: PMC10248849.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    12. Cell type deconvolution of bulk blood RNA-Seq to reveal biological insights of neuropsychiatric disorders. bioRxiv. 2023 May 25. Boltz T, Schwarz T, Bot M, Hou K, Caggiano C, Lapinska S, Duan C, Boks MP, Kahn RS, Zaitlen N, Pasaniuc B, Ophoff R. PMID: 37293101; PMCID: PMC10245943.
      View in: PubMed   Mentions:
    13. Impact of cross-ancestry genetic architecture on GWASs in admixed populations. Am J Hum Genet. 2023 06 01; 110(6):927-939. Mester R, Hou K, Ding Y, Meeks G, Burch KS, Bhattacharya A, Henn BM, Pasaniuc B. PMID: 37224807; PMCID: PMC10257009.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    14. Polygenic scoring accuracy varies across the genetic ancestry continuum. Nature. 2023 Jun; 618(7966):774-781. Ding Y, Hou K, Xu Z, Pimplaskar A, Petter E, Boulier K, Privé F, Vilhjálmsson BJ, Olde Loohuis LM, Pasaniuc B. PMID: 37198491; PMCID: PMC10284707.
      View in: PubMed   Mentions: 11     Fields:    Translation:Humans
    15. twas_sim, a Python-based tool for simulation and power analysis of transcriptome-wide association analysis. Bioinformatics. 2023 05 04; 39(5). Wang X, Lu Z, Bhattacharya A, Pasaniuc B, Mancuso N. PMID: 37099718; PMCID: PMC10172036.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    16. Causal effects on complex traits are similar for common variants across segments of different continental ancestries within admixed individuals. Nat Genet. 2023 04; 55(4):549-558. Hou K, Ding Y, Xu Z, Wu Y, Bhattacharya A, Mester R, Belbin GM, Buyske S, Conti DV, Darst BF, Fornage M, Gignoux C, Guo X, Haiman C, Kenny EE, Kim M, Kooperberg C, Lange L, Manichaikul A, North KE, Peters U, Rasmussen-Torvik LJ, Rich SS, Rotter JI, Wheeler HE, Wojcik GL, Zhou Y, Sankararaman S, Pasaniuc B. PMID: 36941441.
      View in: PubMed   Mentions: 10     Fields:    Translation:Humans
    17. Cross-ancestry, cell-type-informed atlas of gene, isoform, and splicing regulation in the developing human brain. medRxiv. 2023 Mar 06. Wen C, Margolis M, Dai R, Zhang P, Przytycki PF, Vo DD, Bhattacharya A, Kim M, Matoba N, Tsai E, Hoh C, Jiao C, Aygun N, Walker RL, Chatzinakos C, Clarke D, Pratt H, PsychENCODE Consortium, Peters MA, Gerstein M, Daskalakis NP, Weng Z, Jaffe AE, Kleinman JE, Hyde TM, Weinberger DR, Bray NJ, Sestan N, Geschwind DH, Roeder K, Gusev A, Pasaniuc B, Stein JL, Love MI, Pollard KS, Liu C, Gandal MJ. PMID: 36945630; PMCID: PMC10029021.
      View in: PubMed   Mentions:
    18. Optimized high-throughput screening of non-coding variants identified from genome-wide association studies. Nucleic Acids Res. 2023 02 22; 51(3):e18. Morova T, Ding Y, Huang CF, Sar F, Schwarz T, Giambartolomei C, Baca SC, Grishin D, Hach F, Gusev A, Freedman ML, Pasaniuc B, Lack NA. PMID: 36546757; PMCID: PMC9943666.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    19. The UCLA ATLAS Community Health Initiative: Promoting precision health research in a diverse biobank. Cell Genom. 2023 Jan 11; 3(1):100243. Johnson R, Ding Y, Bhattacharya A, Knyazev S, Chiu A, Lajonchere C, Geschwind DH, Pasaniuc B. PMID: 36777178; PMCID: PMC9903668.
      View in: PubMed   Mentions: 2  
    20. Session Introduction: Overcoming health disparities in precision medicine. Pac Symp Biocomput. 2023; 28:181-185. Barnes KC, De La Vega FM, Bustamante CD, Gignoux CR, Kenny E, Mathias RA, Pasaniuc B. PMID: 36540975.
      View in: PubMed   Mentions:    Fields:    
    21. Extensive androgen receptor enhancer heterogeneity in primary prostate cancers underlies transcriptional diversity and metastatic potential. Nat Commun. 2022 11 30; 13(1):7367. Kneppers J, Severson TM, Siefert JC, Schol P, Joosten SEP, Yu IPL, Huang CF, Morova T, Altintas UB, Giambartolomei C, Seo JH, Baca SC, Carneiro I, Emberly E, Pasaniuc B, Jerónimo C, Henrique R, Freedman ML, Wessels LFA, Lack NA, Bergman AM, Zwart W. PMID: 36450752; PMCID: PMC9712620.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    22. Exome-wide association study to identify rare variants influencing COVID-19 outcomes: Results from the Host Genetics Initiative. PLoS Genet. 2022 11; 18(11):e1010367. Butler-Laporte G, Povysil G, Kosmicki JA, Cirulli ET, Drivas T, Furini S, Saad C, Schmidt A, Olszewski P, Korotko U, Quinodoz M, Çelik E, Kundu K, Walter K, Jung J, Stockwell AD, Sloofman LG, Jordan DM, Thompson RC, Del Valle D, Simons N, Cheng E, Sebra R, Schadt EE, Kim-Schulze S, Gnjatic S, Merad M, Buxbaum JD, Beckmann ND, Charney AW, Przychodzen B, Chang T, Pottinger TD, Shang N, Brand F, Fava F, Mari F, Chwialkowska K, Niemira M, Pula S, Baillie JK, Stuckey A, Salas A, Bello X, Pardo-Seco J, Gómez-Carballa A, Rivero-Calle I, Martinón-Torres F, Ganna A, Karczewski KJ, Veerapen K, Bourgey M, Bourque G, Eveleigh RJ, Forgetta V, Morrison D, Langlais D, Lathrop M, Mooser V, Nakanishi T, Frithiof R, Hultström M, Lipcsey M, Marincevic-Zuniga Y, Nordlund J, Schiabor Barrett KM, Lee W, Bolze A, White S, Riffle S, Tanudjaja F, Sandoval E, Neveux I, Dabe S, Casadei N, Motameny S, Alaamery M, Massadeh S, Aljawini N, Almutairi MS, Arabi YM, Alqahtani SA, Al Harthi FS, Almutairi A, Alqubaishi F, Alotaibi S, Binowayn A, Alsolm EA, El Bardisy H, Fawzy M, Cai F, Soranzo N, Butterworth A, COVID-19 Host Genetics Initiative, DeCOI Host Genetics Group, GEN-COVID Multicenter Study (Italy), Mount Sinai Clinical Intelligence Center, GEN-COVID consortium (Spain), GenOMICC Consortium, Japan COVID-19 Task Force, Regeneron Genetics Center, Geschwind DH, Arteaga S, Stephens A, Butte MJ, Boutros PC, Yamaguchi TN, Tao S, Eng S, Sanders T, Tung PJ, Broudy ME, Pan Y, Gonzalez A, Chavan N, Johnson R, Pasaniuc B, Yaspan B, Smieszek S, Rivolta C, Bibert S, Bochud PY, Dabrowski M, Zawadzki P, Sypniewski M, Kaja E, Chariyavilaskul P, Nilaratanakul V, Hirankarn N, Shotelersuk V, Pongpanich M, Phokaew C, Chetruengchai W, Tokunaga K, Sugiyama M, Kawai Y, Hasegawa T, Naito T, Namkoong H, Edahiro R, Kimura A, Ogawa S, Kanai T, Fukunaga K, Okada Y, Imoto S, Miyano S, Mangul S, Abedalthagafi MS, Zeberg H, Grzymski JJ, Washington NL, Ossowski S, Ludwig KU, Schulte EC, Riess O, Moniuszko M, Kwasniewski M, Mbarek H, Ismail SI, Verma A, Goldstein DB, Kiryluk K, Renieri A, Ferreira MAR, Richards JB. PMID: 36327219; PMCID: PMC9632827.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansCells
    23. Broad transcriptomic dysregulation occurs across the cerebral cortex in ASD. Nature. 2022 Nov; 611(7936):532-539. Gandal MJ, Haney JR, Wamsley B, Yap CX, Parhami S, Emani PS, Chang N, Chen GT, Hoftman GD, de Alba D, Ramaswami G, Hartl CL, Bhattacharya A, Luo C, Jin T, Wang D, Kawaguchi R, Quintero D, Ou J, Wu YE, Parikshak NN, Swarup V, Belgard TG, Gerstein M, Pasaniuc B, Geschwind DH. PMID: 36323788; PMCID: PMC9668748.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansCells
    24. Best practices for multi-ancestry, meta-analytic transcriptome-wide association studies: Lessons from the Global Biobank Meta-analysis Initiative. Cell Genom. 2022 Oct 12; 2(10). Bhattacharya A, Hirbo JB, Zhou D, Zhou W, Zheng J, Kanai M, Global Biobank Meta-analysis Initiative, Pasaniuc B, Gamazon ER, Cox NJ. PMID: 36341024; PMCID: PMC9631681.
      View in: PubMed   Mentions: 5  
    25. Global Biobank Meta-analysis Initiative: Powering genetic discovery across human disease. Cell Genom. 2022 Oct 12; 2(10):100192. Zhou W, Kanai M, Wu KH, Rasheed H, Tsuo K, Hirbo JB, Wang Y, Bhattacharya A, Zhao H, Namba S, Surakka I, Wolford BN, Lo Faro V, Lopera-Maya EA, Läll K, Favé MJ, Partanen JJ, Chapman SB, Karjalainen J, Kurki M, Maasha M, Brumpton BM, Chavan S, Chen TT, Daya M, Ding Y, Feng YA, Guare LA, Gignoux CR, Graham SE, Hornsby WE, Ingold N, Ismail SI, Johnson R, Laisk T, Lin K, Lv J, Millwood IY, Moreno-Grau S, Nam K, Palta P, Pandit A, Preuss MH, Saad C, Setia-Verma S, Thorsteinsdottir U, Uzunovic J, Verma A, Zawistowski M, Zhong X, Afifi N, Al-Dabhani KM, Al Thani A, Bradford Y, Campbell A, Crooks K, de Bock GH, Damrauer SM, Douville NJ, Finer S, Fritsche LG, Fthenou E, Gonzalez-Arroyo G, Griffiths CJ, Guo Y, Hunt KA, Ioannidis A, Jansonius NM, Konuma T, Lee MTM, Lopez-Pineda A, Matsuda Y, Marioni RE, Moatamed B, Nava-Aguilar MA, Numakura K, Patil S, Rafaels N, Richmond A, Rojas-Muñoz A, Shortt JA, Straub P, Tao R, Vanderwerff B, Vernekar M, Veturi Y, Barnes KC, Boezen M, Chen Z, Chen CY, Cho J, Smith GD, Finucane HK, Franke L, Gamazon ER, Ganna A, Gaunt TR, Ge T, Huang H, Huffman J, Katsanis N, Koskela JT, Lajonchere C, Law MH, Li L, Lindgren CM, Loos RJF, MacGregor S, Matsuda K, Olsen CM, Porteous DJ, Shavit JA, Snieder H, Takano T, Trembath RC, Vonk JM, Whiteman DC, Wicks SJ, Wijmenga C, Wright J, Zheng J, Zhou X, Awadalla P, Boehnke M, Bustamante CD, Cox NJ, Fatumo S, Geschwind DH, Hayward C, Hveem K, Kenny EE, Lee S, Lin YF, Mbarek H, Mägi R, Martin HC, Medland SE, Okada Y, Palotie AV, Pasaniuc B, Rader DJ, Ritchie MD, Sanna S, Smoller JW, Stefansson K, van Heel DA, Walters RG, Zöllner S, Biobank of the Americas, Biobank Japan Project, BioMe, BioVU, CanPath - Ontario Health Study, China Kadoorie Biobank Collaborative Group, Colorado Center for Personalized Medicine, deCODE Genetics, Estonian Biobank, FinnGen, Generation Scotland, Genes & Health Research Team, LifeLines, Mass General Brigham Biobank, Michigan Genomics Initiative, National Biobank of Korea, Penn Medicine BioBank, Qatar Biobank, QSkin Sun and Health Study, Taiwan Biobank, HUNT Study, UCLA ATLAS Community Health Initiative, Uganda Genome Resource, UK Biobank, Martin AR, Willer CJ, Daly MJ, Neale BM. PMID: 36777996; PMCID: PMC9903716.
      View in: PubMed   Mentions: 41  
    26. Genetic determinants of chromatin reveal prostate cancer risk mediated by context-dependent gene regulation. Nat Genet. 2022 09; 54(9):1364-1375. Baca SC, Singler C, Zacharia S, Seo JH, Morova T, Hach F, Ding Y, Schwarz T, Huang CF, Anderson J, Fay AP, Kalita C, Groha S, Pomerantz MM, Wang V, Linder S, Sweeney CJ, Zwart W, Lack NA, Pasaniuc B, Takeda DY, Gusev A, Freedman ML. PMID: 36071171; PMCID: PMC9784646.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansCells
    27. Drug-Induced Epigenomic Plasticity Reprograms Circadian Rhythm Regulation to Drive Prostate Cancer toward Androgen Independence. Cancer Discov. 2022 09 02; 12(9):2074-2097. Linder S, Hoogstraat M, Stelloo S, Eickhoff N, Schuurman K, de Barros H, Alkemade M, Bekers EM, Severson TM, Sanders J, Huang CF, Morova T, Altintas UB, Hoekman L, Kim Y, Baca SC, Sjöström M, Zaalberg A, Hintzen DC, de Jong J, Kluin RJC, de Rink I, Giambartolomei C, Seo JH, Pasaniuc B, Altelaar M, Medema RH, Feng FY, Zoubeidi A, Freedman ML, Wessels LFA, Butler LM, Lack NA, van der Poel H, Bergman AM, Zwart W. PMID: 35754340; PMCID: PMC7613567.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCells
    28. Polygenic enrichment distinguishes disease associations of individual cells in single-cell RNA-seq data. Nat Genet. 2022 10; 54(10):1572-1580. Zhang MJ, Hou K, Dey KK, Sakaue S, Jagadeesh KA, Weinand K, Taychameekiatchai A, Rao P, Pisco AO, Zou J, Wang B, Gandal M, Raychaudhuri S, Pasaniuc B, Price AL. PMID: 36050550; PMCID: PMC9891382.
      View in: PubMed   Mentions: 11     Fields:    
    29. Multi-ancestry fine-mapping improves precision to identify causal genes in transcriptome-wide association studies. Am J Hum Genet. 2022 08 04; 109(8):1388-1404. Lu Z, Gopalan S, Yuan D, Conti DV, Pasaniuc B, Gusev A, Mancuso N. PMID: 35931050; PMCID: PMC9388396.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansCells
    30. Combining SNP-to-gene linking strategies to identify disease genes and assess disease omnigenicity. Nat Genet. 2022 06; 54(6):827-836. Gazal S, Weissbrod O, Hormozdiari F, Dey KK, Nasser J, Jagadeesh KA, Weiner DJ, Shi H, Fulco CP, O'Connor LJ, Pasaniuc B, Engreitz JM, Price AL. PMID: 35668300; PMCID: PMC9894581.
      View in: PubMed   Mentions: 24     Fields:    
    31. Powerful eQTL mapping through low-coverage RNA sequencing. HGG Adv. 2022 Jul 14; 3(3):100103. Schwarz T, Boltz T, Hou K, Bot M, Duan C, Loohuis LO, Boks MP, Kahn RS, Ophoff RA, Pasaniuc B. PMID: 35519825; PMCID: PMC9062329.
      View in: PubMed   Mentions:
    32. Unlocking capacities of genomics for the COVID-19 response and future pandemics. Nat Methods. 2022 04; 19(4):374-380. Knyazev S, Chhugani K, Sarwal V, Ayyala R, Singh H, Karthikeyan S, Deshpande D, Baykal PI, Comarova Z, Lu A, Porozov Y, Vasylyeva TI, Wertheim JO, Tierney BT, Chiu CY, Sun R, Wu A, Abedalthagafi MS, Pak VM, Nagaraj SH, Smith AL, Skums P, Pasaniuc B, Komissarov A, Mason CE, Bortz E, Lemey P, Kondrashov F, Beerenwinkel N, Lam TT, Wu NC, Zelikovsky A, Knight R, Crandall KA, Mangul S. PMID: 35396471; PMCID: PMC9467803.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansCellsPHPublic Health
    33. Partitioning gene-level contributions to complex-trait heritability by allele frequency identifies disease-relevant genes. Am J Hum Genet. 2022 04 07; 109(4):692-709. Burch KS, Hou K, Ding Y, Wang Y, Gazal S, Shi H, Pasaniuc B. PMID: 35271803; PMCID: PMC9069080.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    34. Genetically regulated multi-omics study for symptom clusters of posttraumatic stress disorder highlights pleiotropy with hematologic and cardio-metabolic traits. Mol Psychiatry. 2022 03; 27(3):1394-1404. Pathak GA, Singh K, Wendt FR, Fleming TW, Overstreet C, Koller D, Tylee DS, De Angelis F, Cabrera Mendoza B, Levey DF, Koenen KC, Krystal JH, Pietrzak RH, O' Donell C, Gaziano JM, Falcone G, Stein MB, Gelernter J, Pasaniuc B, Mancuso N, Davis LK, Polimanti R. PMID: 35241783; PMCID: PMC9210390.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    35. A summary-statistics-based approach to examine the role of serotonin transporter promoter tandem repeat polymorphism in psychiatric phenotypes. Eur J Hum Genet. 2022 05; 30(5):547-554. Majumdar A, Patel P, Pasaniuc B, Ophoff RA. PMID: 34949768; PMCID: PMC9091198.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    36. Large uncertainty in individual polygenic risk score estimation impacts PRS-based risk stratification. Nat Genet. 2022 01; 54(1):30-39. Ding Y, Hou K, Burch KS, Lapinska S, Privé F, Vilhjálmsson B, Sankararaman S, Pasaniuc B. PMID: 34931067; PMCID: PMC8758557.
      View in: PubMed   Mentions: 27     Fields:    Translation:Humans
    37. Fast estimation of genetic correlation for biobank-scale data. Am J Hum Genet. 2022 01 06; 109(1):24-32. Wu Y, Burch KS, Ganna A, Pajukanta P, Pasaniuc B, Sankararaman S. PMID: 34861179; PMCID: PMC8764132.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    38. On powerful GWAS in admixed populations. Nat Genet. 2021 12; 53(12):1631-1633. Hou K, Bhattacharya A, Mester R, Burch KS, Pasaniuc B. PMID: 34824480; PMCID: PMC8939372.
      View in: PubMed   Mentions: 10     Fields:    
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    76. Probabilistic fine-mapping of transcriptome-wide association studies. Nat Genet. 2019 04; 51(4):675-682. Mancuso N, Freund MK, Johnson R, Shi H, Kichaev G, Gusev A, Pasaniuc B. PMID: 30926970; PMCID: PMC6619422.
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    77. Opportunities and challenges for transcriptome-wide association studies. Nat Genet. 2019 04; 51(4):592-599. Wainberg M, Sinnott-Armstrong N, Mancuso N, Barbeira AN, Knowles DA, Golan D, Ermel R, Ruusalepp A, Quertermous T, Hao K, Björkegren JLM, Im HK, Pasaniuc B, Rivas MA, Kundaje A. PMID: 30926968; PMCID: PMC6777347.
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    79. Author Correction: Large-scale transcriptome-wide association study identifies new prostate cancer risk regions. Nat Commun. 2019 01 08; 10(1):171. Mancuso N, Gayther S, Gusev A, Zheng W, Penney KL, PRACTICAL consortium, Kote-Jarai Z, Eeles R, Freedman M, Haiman C, Pasaniuc B. PMID: 30622272; PMCID: PMC6325152.
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    81. GWAS and colocalization analyses implicate carotid intima-media thickness and carotid plaque loci in cardiovascular outcomes. Nat Commun. 2018 12 03; 9(1):5141. Franceschini N, Giambartolomei C, de Vries PS, Finan C, Bis JC, Huntley RP, Lovering RC, Tajuddin SM, Winkler TW, Graff M, Kavousi M, Dale C, Smith AV, Hofer E, van Leeuwen EM, Nolte IM, Lu L, Scholz M, Sargurupremraj M, Pitkänen N, Franzén O, Joshi PK, Noordam R, Marioni RE, Hwang SJ, Musani SK, Schminke U, Palmas W, Isaacs A, Correa A, Zonderman AB, Hofman A, Teumer A, Cox AJ, Uitterlinden AG, Wong A, Smit AJ, Newman AB, Britton A, Ruusalepp A, Sennblad B, Hedblad B, Pasaniuc B, Penninx BW, Langefeld CD, Wassel CL, Tzourio C, Fava C, Baldassarre D, O'Leary DH, Teupser D, Kuh D, Tremoli E, Mannarino E, Grossi E, Boerwinkle E, Schadt EE, Ingelsson E, Veglia F, Rivadeneira F, Beutner F, Chauhan G, Heiss G, Snieder H, Campbell H, Völzke H, Markus HS, Deary IJ, Jukema JW, de Graaf J, Price J, Pott J, Hopewell JC, Liang J, Thiery J, Engmann J, Gertow K, Rice K, Taylor KD, Dhana K, Kiemeney LALM, Lind L, Raffield LM, Launer LJ, Holdt LM, Dörr M, Dichgans M, Traylor M, Sitzer M, Kumari M, Kivimaki M, Nalls MA, Melander O, Raitakari O, Franco OH, Rueda-Ochoa OL, Roussos P, Whincup PH, Amouyel P, Giral P, Anugu P, Wong Q, Malik R, Rauramaa R, Burkhardt R, Hardy R, Schmidt R, de Mutsert R, Morris RW, Strawbridge RJ, Wannamethee SG, Hägg S, Shah S, McLachlan S, Trompet S, Seshadri S, Kurl S, Heckbert SR, Ring S, Harris TB, Lehtimäki T, Galesloot TE, Shah T, de Faire U, Plagnol V, Rosamond WD, Post W, Zhu X, Zhang X, Guo X, Saba Y, MEGASTROKE Consortium, Dehghan A, Seldenrijk A, Morrison AC, Hamsten A, Psaty BM, van Duijn CM, Lawlor DA, Mook-Kanamori DO, Bowden DW, Schmidt H, Wilson JF, Wilson JG, Rotter JI, Wardlaw JM, Deanfield J, Halcox J, Lyytikäinen LP, Loeffler M, Evans MK, Debette S, Humphries SE, Völker U, Gudnason V, Hingorani AD, Björkegren JLM, Casas JP, O'Donnell CJ. PMID: 30510157; PMCID: PMC6277418.
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    82. Large-scale transcriptome-wide association study identifies new prostate cancer risk regions. Nat Commun. 2018 10 04; 9(1):4079. Mancuso N, Gayther S, Gusev A, Zheng W, Penney KL, Kote-Jarai Z, Eeles R, Freedman M, Haiman C, Pasaniuc B, PRACTICAL consortium. PMID: 30287866; PMCID: PMC6172280.
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    83. Phenotype-Specific Enrichment of Mendelian Disorder Genes near GWAS Regions across 62 Complex Traits. Am J Hum Genet. 2018 10 04; 103(4):535-552. Freund MK, Burch KS, Shi H, Mancuso N, Kichaev G, Garske KM, Pan DZ, Miao Z, Mohlke KL, Laakso M, Pajukanta P, Pasaniuc B, Arboleda VA. PMID: 30290150; PMCID: PMC6174356.
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    84. A Bayesian framework for multiple trait colocalization from summary association statistics. Bioinformatics. 2018 08 01; 34(15):2538-2545. Giambartolomei C, Zhenli Liu J, Zhang W, Hauberg M, Shi H, Boocock J, Pickrell J, Jaffe AE, CommonMind Consortium, Pasaniuc B, Roussos P. PMID: 29579179; PMCID: PMC6061859.
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    85. A unifying framework for joint trait analysis under a non-infinitesimal model. Bioinformatics. 2018 07 01; 34(13):i195-i201. Johnson R, Shi H, Pasaniuc B, Sankararaman S. PMID: 29949958; PMCID: PMC6022541.
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    86. Transcriptome-wide association studies accounting for colocalization using Egger regression. Genet Epidemiol. 2018 07; 42(5):418-433. Barfield R, Feng H, Gusev A, Wu L, Zheng W, Pasaniuc B, Kraft P. PMID: 29808603; PMCID: PMC6342197.
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    87. Transcriptome-wide association study of schizophrenia and chromatin activity yields mechanistic disease insights. Nat Genet. 2018 04; 50(4):538-548. Gusev A, Mancuso N, Won H, Kousi M, Finucane HK, Reshef Y, Song L, Safi A, Schizophrenia Working Group of the Psychiatric Genomics Consortium, McCarroll S, Neale BM, Ophoff RA, O'Donovan MC, Crawford GE, Geschwind DH, Katsanis N, Sullivan PF, Pasaniuc B, Price AL. PMID: 29632383; PMCID: PMC5942893.
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    88. Methods for fine-mapping with chromatin and expression data. PLoS Genet. 2018 02; 14(2):e1007240. Roytman M, Kichaev G, Gusev A, Pasaniuc B. PMID: 29481575; PMCID: PMC5843356.
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    89. Local Genetic Correlation Gives Insights into the Shared Genetic Architecture of Complex Traits. Am J Hum Genet. 2017 Nov 02; 101(5):737-751. Shi H, Mancuso N, Spendlove S, Pasaniuc B. PMID: 29100087; PMCID: PMC5673668.
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    90. Erratum to: A multi-stage genome-wide association study of uterine fibroids in African Americans. Hum Genet. 2017 11; 136(11-12):1497-1498. Hellwege JN, Jeff JM, Wise LA, Gallagher CS, Wellons M, Hartmann KE, Jones SF, Torstenson ES, Dickinson S, Ruiz-Narváez EA, Rohland N, Allen A, Reich D, Tandon A, Pasaniuc B, Mancuso N, Im HK, Hinds DA, Palmer JR, Rosenberg L, Denny JC, Roden DM, Stewart EA, Morton CC, Kenny EE, Edwards TL, Velez Edwards DR. PMID: 28975356; PMCID: PMC5909202.
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    92. Enhanced methods to detect haplotypic effects on gene expression. Bioinformatics. 2017 Aug 01; 33(15):2307-2313. Brown R, Kichaev G, Mancuso N, Boocock J, Pasaniuc B. PMID: 28369161; PMCID: PMC5860109.
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    93. Widespread Allelic Heterogeneity in Complex Traits. Am J Hum Genet. 2017 May 04; 100(5):789-802. Hormozdiari F, Zhu A, Kichaev G, Ju CJ, Segrè AV, Joo JWJ, Won H, Sankararaman S, Pasaniuc B, Shifman S, Eskin E. PMID: 28475861; PMCID: PMC5420356.
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    94. A Genetic Population Isolate in The Netherlands Showing Extensive Haplotype Sharing and Long Regions of Homozygosity. Genes (Basel). 2017 May 04; 8(5). Somers M, Olde Loohuis LM, Aukes MF, Pasaniuc B, de Visser KCL, Kahn RS, Sommer IE, Ophoff RA. PMID: 28471380; PMCID: PMC5448007.
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    95. Integrating Gene Expression with Summary Association Statistics to Identify Genes Associated with 30 Complex Traits. Am J Hum Genet. 2017 Mar 02; 100(3):473-487. Mancuso N, Shi H, Goddard P, Kichaev G, Gusev A, Pasaniuc B. PMID: 28238358; PMCID: PMC5339290.
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    96. Fine-mapping of lipid regions in global populations discovers ethnic-specific signals and refines previously identified lipid loci. Hum Mol Genet. 2016 12 15; 25(24):5500-5512. Zubair N, Graff M, Luis Ambite J, Bush WS, Kichaev G, Lu Y, Manichaikul A, Sheu WH, Absher D, Assimes TL, Bielinski SJ, Bottinger EP, Buzkova P, Chuang LM, Chung RH, Cochran B, Dumitrescu L, Gottesman O, Haessler JW, Haiman C, Heiss G, Hsiung CA, Hung YJ, Hwu CM, Juang JJ, Le Marchand L, Lee IT, Lee WJ, Lin LA, Lin D, Lin SY, Mackey RH, Martin LW, Pasaniuc B, Peters U, Predazzi I, Quertermous T, Reiner AP, Robinson J, Rotter JI, Ryckman KK, Schreiner PJ, Stahl E, Tao R, Tsai MY, Waite LL, Wang TD, Buyske S, Ida Chen YD, Cheng I, Crawford DC, Loos RJF, Rich SS, Fornage M, North KE, Kooperberg C, Carty CL. PMID: 28426890; PMCID: PMC5721937.
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    97. Colocalization of GWAS and eQTL Signals Detects Target Genes. Am J Hum Genet. 2016 Dec 01; 99(6):1245-1260. Hormozdiari F, van de Bunt M, Segrè AV, Li X, Joo JWJ, Bilow M, Sul JH, Sankararaman S, Pasaniuc B, Eskin E. PMID: 27866706; PMCID: PMC5142122.
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    98. Dissecting the genetics of complex traits using summary association statistics. Nat Rev Genet. 2017 02; 18(2):117-127. Pasaniuc B, Price AL. PMID: 27840428; PMCID: PMC5449190.
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    99. Improved methods for multi-trait fine mapping of pleiotropic risk loci. Bioinformatics. 2017 01 15; 33(2):248-255. Kichaev G, Roytman M, Johnson R, Eskin E, Lindström S, Kraft P, Pasaniuc B. PMID: 27663501; PMCID: PMC5254076.
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    100. Contrasting the Genetic Architecture of 30 Complex Traits from Summary Association Data. Am J Hum Genet. 2016 07 07; 99(1):139-53. Shi H, Kichaev G, Pasaniuc B. PMID: 27346688; PMCID: PMC5005444.
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    101. Atlas of prostate cancer heritability in European and African-American men pinpoints tissue-specific regulation. Nat Commun. 2016 Apr 07; 7:10979. Gusev A, Shi H, Kichaev G, Pomerantz M, Li F, Long HW, Ingles SA, Kittles RA, Strom SS, Rybicki BA, Nemesure B, Isaacs WB, Zheng W, Pettaway CA, Yeboah ED, Tettey Y, Biritwum RB, Adjei AA, Tay E, Truelove A, Niwa S, Chokkalingam AP, John EM, Murphy AB, Signorello LB, Carpten J, Leske MC, Wu SY, Hennis AJ, Neslund-Dudas C, Hsing AW, Chu L, Goodman PJ, Klein EA, Witte JS, Casey G, Kaggwa S, Cook MB, Stram DO, Blot WJ, Eeles RA, Easton D, Kote-Jarai Z, Al Olama AA, Benlloch S, Muir K, Giles GG, Southey MC, Fitzgerald LM, Gronberg H, Wiklund F, Aly M, Henderson BE, Schleutker J, Wahlfors T, Tammela TL, Nordestgaard BG, Key TJ, Travis RC, Neal DE, Donovan JL, Hamdy FC, Pharoah P, Pashayan N, Khaw KT, Stanford JL, Thibodeau SN, McDonnell SK, Schaid DJ, Maier C, Vogel W, Luedeke M, Herkommer K, Kibel AS, Cybulski C, Wokolorczyk D, Kluzniak W, Cannon-Albright L, Teerlink C, Brenner H, Dieffenbach AK, Arndt V, Park JY, Sellers TA, Lin HY, Slavov C, Kaneva R, Mitev V, Batra J, Spurdle A, Clements JA, Teixeira MR, Pandha H, Michael A, Paulo P, Maia S, Kierzek A, PRACTICAL consortium, Conti DV, Albanes D, Berg C, Berndt SI, Campa D, Crawford ED, Diver WR, Gapstur SM, Gaziano JM, Giovannucci E, Hoover R, Hunter DJ, Johansson M, Kraft P, Le Marchand L, Lindström S, Navarro C, Overvad K, Riboli E, Siddiq A, Stevens VL, Trichopoulos D, Vineis P, Yeager M, Trynka G, Raychaudhuri S, Schumacher FR, Price AL, Freedman ML, Haiman CA, Pasaniuc B. PMID: 27052111; PMCID: PMC4829663.
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    102. Integrative approaches for large-scale transcriptome-wide association studies. Nat Genet. 2016 Mar; 48(3):245-52. Gusev A, Ko A, Shi H, Bhatia G, Chung W, Penninx BW, Jansen R, de Geus EJ, Boomsma DI, Wright FA, Sullivan PF, Nikkola E, Alvarez M, Civelek M, Lusis AJ, Lehtimäki T, Raitoharju E, Kähönen M, Seppälä I, Raitakari OT, Kuusisto J, Laakso M, Price AL, Pajukanta P, Pasaniuc B. PMID: 26854917; PMCID: PMC4767558.
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    103. Prostate Cancer Susceptibility in Men of African Ancestry at 8q24. J Natl Cancer Inst. 2016 Jul; 108(7). Han Y, Rand KA, Hazelett DJ, Ingles SA, Kittles RA, Strom SS, Rybicki BA, Nemesure B, Isaacs WB, Stanford JL, Zheng W, Schumacher FR, Berndt SI, Wang Z, Xu J, Rohland N, Reich D, Tandon A, Pasaniuc B, Allen A, Quinque D, Mallick S, Notani D, Rosenfeld MG, Jayani RS, Kolb S, Gapstur SM, Stevens VL, Pettaway CA, Yeboah ED, Tettey Y, Biritwum RB, Adjei AA, Tay E, Truelove A, Niwa S, Chokkalingam AP, John EM, Murphy AB, Signorello LB, Carpten J, Leske MC, Wu SY, Hennis AJM, Neslund-Dudas C, Hsing AW, Chu L, Goodman PJ, Klein EA, Zheng SL, Witte JS, Casey G, Lubwama A, Pooler LC, Sheng X, Coetzee GA, Cook MB, Chanock SJ, Stram DO, Watya S, Blot WJ, Conti DV, Henderson BE, Haiman CA. PMID: 26823525; PMCID: PMC4948565.
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    104. Whole-exome sequencing of over 4100 men of African ancestry and prostate cancer risk. Hum Mol Genet. 2016 Jan 15; 25(2):371-81. Rand KA, Rohland N, Tandon A, Stram A, Sheng X, Do R, Pasaniuc B, Allen A, Quinque D, Mallick S, Le Marchand L, Kaggwa S, Lubwama A, African Ancestry Prostate Cancer GWAS Consortium, ELLIPSE/GAME-ON Consortium, Stram DO, Watya S, Henderson BE, Conti DV, Reich D, Haiman CA. PMID: 26604137; PMCID: PMC4865031.
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    105. The contribution of rare variation to prostate cancer heritability. Nat Genet. 2016 Jan; 48(1):30-5. Mancuso N, Rohland N, Rand KA, Tandon A, Allen A, Quinque D, Mallick S, Li H, Stram A, Sheng X, Kote-Jarai Z, Easton DF, Eeles RA, PRACTICAL consortium, Le Marchand L, Lubwama A, Stram D, Watya S, Conti DV, Henderson B, Haiman CA, Pasaniuc B, Reich D. PMID: 26569126; PMCID: PMC7534691.
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    106. Leveraging local ancestry to detect gene-gene interactions in genome-wide data. BMC Genet. 2015 Oct 24; 16:124. Aschard H, Gusev A, Brown R, Pasaniuc B. PMID: 26498930; PMCID: PMC4619349.
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    107. Modeling Linkage Disequilibrium Increases Accuracy of Polygenic Risk Scores. Am J Hum Genet. 2015 Oct 01; 97(4):576-92. Vilhjálmsson BJ, Yang J, Finucane HK, Gusev A, Lindström S, Ripke S, Genovese G, Loh PR, Bhatia G, Do R, Hayeck T, Won HH, Schizophrenia Working Group of the Psychiatric Genomics Consortium, Discovery, Biology, and Risk of , Kathiresan S, Pato M, Pato C, Tamimi R, Stahl E, Zaitlen N, Pasaniuc B, Belbin G, Kenny EE, Schierup MH, De Jager P, Patsopoulos NA, McCarroll S, Daly M, Purcell S, Chasman D, Neale B, Goddard M, Visscher PM, Kraft P, Patterson N, Price AL. PMID: 26430803; PMCID: PMC4596916.
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    108. Leveraging Functional-Annotation Data in Trans-ethnic Fine-Mapping Studies. Am J Hum Genet. 2015 Aug 06; 97(2):260-71. Kichaev G, Pasaniuc B. PMID: 26189819; PMCID: PMC4573268.
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    109. A multivariate Bernoulli model to predict DNaseI hypersensitivity status from haplotype data. Bioinformatics. 2015 Nov 01; 31(21):3514-21. Shi H, Pasaniuc B, Lange KL. PMID: 26139633; PMCID: PMC4836401.
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    111. Leveraging ancestry to improve causal variant identification in exome sequencing for monogenic disorders. Eur J Hum Genet. 2016 Jan; 24(1):113-9. Brown R, Lee H, Eskin A, Kichaev G, Lohmueller KE, Reversade B, Nelson SF, Pasaniuc B. PMID: 25898925; PMCID: PMC4795218.
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    112. A spatial haplotype copying model with applications to genotype imputation. J Comput Biol. 2015 May; 22(5):451-62. Yang WY, Hormozdiari F, Eskin E, Pasaniuc B. PMID: 25526526; PMCID: PMC4425418.
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    113. Leveraging population admixture to characterize the heritability of complex traits. Nat Genet. 2014 Dec; 46(12):1356-62. Zaitlen N, Pasaniuc B, Sankararaman S, Bhatia G, Zhang J, Gusev A, Young T, Tandon A, Pollack S, Vilhjálmsson BJ, Assimes TL, Berndt SI, Blot WJ, Chanock S, Franceschini N, Goodman PG, He J, Hennis AJ, Hsing A, Ingles SA, Isaacs W, Kittles RA, Klein EA, Lange LA, Nemesure B, Patterson N, Reich D, Rybicki BA, Stanford JL, Stevens VL, Strom SS, Whitsel EA, Witte JS, Xu J, Haiman C, Wilson JG, Kooperberg C, Stram D, Reiner AP, Tang H, Price AL. PMID: 25383972; PMCID: PMC4244251.
      View in: PubMed   Mentions: 37     Fields:    Translation:Humans
    114. Partitioning heritability of regulatory and cell-type-specific variants across 11 common diseases. Am J Hum Genet. 2014 Nov 06; 95(5):535-52. Gusev A, Lee SH, Trynka G, Finucane H, Vilhjálmsson BJ, Xu H, Zang C, Ripke S, Bulik-Sullivan B, Stahl E, Schizophrenia Working Group of the Psychiatric Genomics Consortium, SWE-SCZ Consortium, Kähler AK, Hultman CM, Purcell SM, McCarroll SA, Daly M, Pasaniuc B, Sullivan PF, Neale BM, Wray NR, Raychaudhuri S, Price AL, Schizophrenia Working Group of the Psychiatric Genomics Consortium, SWE-SCZ Consortium. PMID: 25439723; PMCID: PMC4225595.
      View in: PubMed   Mentions: 325     Fields:    Translation:Humans
    115. Spatial localization of recent ancestors for admixed individuals. G3 (Bethesda). 2014 Nov 03; 4(12):2505-18. Yang WY, Platt A, Chiang CW, Eskin E, Novembre J, Pasaniuc B. PMID: 25371484; PMCID: PMC4267945.
      View in: PubMed   Mentions: 10     Fields:    Translation:Humans
    116. Integrating functional data to prioritize causal variants in statistical fine-mapping studies. PLoS Genet. 2014 Oct; 10(10):e1004722. Kichaev G, Yang WY, Lindstrom S, Hormozdiari F, Eskin E, Price AL, Kraft P, Pasaniuc B. PMID: 25357204; PMCID: PMC4214605.
      View in: PubMed   Mentions: 245     Fields:    Translation:Humans
    117. Identifying causal variants at loci with multiple signals of association. Genetics. 2014 Oct; 198(2):497-508. Hormozdiari F, Kostem E, Kang EY, Pasaniuc B, Eskin E. PMID: 25104515; PMCID: PMC4196608.
      View in: PubMed   Mentions: 215     Fields:    Translation:Humans
    118. Fast and accurate imputation of summary statistics enhances evidence of functional enrichment. Bioinformatics. 2014 Oct 15; 30(20):2906-14. Pasaniuc B, Zaitlen N, Shi H, Bhatia G, Gusev A, Pickrell J, Hirschhorn J, Strachan DP, Patterson N, Price AL. PMID: 24990607; PMCID: PMC4184260.
      View in: PubMed   Mentions: 97     Fields:    Translation:Humans
    119. Amerindian-specific regions under positive selection harbour new lipid variants in Latinos. Nat Commun. 2014 Jun 02; 5:3983. Ko A, Cantor RM, Weissglas-Volkov D, Nikkola E, Reddy PM, Sinsheimer JS, Pasaniuc B, Brown R, Alvarez M, Rodriguez A, Rodriguez-Guillen R, Bautista IC, Arellano-Campos O, Muñoz-Hernández LL, Salomaa V, Kaprio J, Jula A, Jauhiainen M, Heliövaara M, Raitakari O, Lehtimäki T, Eriksson JG, Perola M, Lohmueller KE, Matikainen N, Taskinen MR, Rodriguez-Torres M, Riba L, Tusie-Luna T, Aguilar-Salinas CA, Pajukanta P. PMID: 24886709; PMCID: PMC4062071.
      View in: PubMed   Mentions: 48     Fields:    Translation:HumansCells
    120. Enhanced methods for local ancestry assignment in sequenced admixed individuals. PLoS Comput Biol. 2014 Apr; 10(4):e1003555. Brown R, Pasaniuc B. PMID: 24743331; PMCID: PMC3990492.
      View in: PubMed   Mentions: 16     Fields:    Translation:Humans
    121. IBD genetics: focus on (dys) regulation in immune cells and the epithelium. Gastroenterology. 2014 Apr; 146(4):896-9. Kaser A, Pasaniuc B. PMID: 24566108.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimalsCells
    122. Quantifying missing heritability at known GWAS loci. PLoS Genet. 2013; 9(12):e1003993. Gusev A, Bhatia G, Zaitlen N, Vilhjalmsson BJ, Diogo D, Stahl EA, Gregersen PK, Worthington J, Klareskog L, Raychaudhuri S, Plenge RM, Pasaniuc B, Price AL. PMID: 24385918; PMCID: PMC3873246.
      View in: PubMed   Mentions: 64     Fields:    Translation:Humans
    123. Leveraging reads that span multiple single nucleotide polymorphisms for haplotype inference from sequencing data. Bioinformatics. 2013 Sep 15; 29(18):2245-52. Yang WY, Hormozdiari F, Wang Z, He D, Pasaniuc B, Eskin E. PMID: 23825370; PMCID: PMC3753566.
      View in: PubMed   Mentions: 15     Fields:    Translation:Humans
    124. Enhanced localization of genetic samples through linkage-disequilibrium correction. Am J Hum Genet. 2013 Jun 06; 92(6):882-94. Baran Y, Quintela I, Carracedo A, Pasaniuc B, Halperin E. PMID: 23726367; PMCID: PMC3675263.
      View in: PubMed   Mentions: 15     Fields:    Translation:Humans
    125. Using extended genealogy to estimate components of heritability for 23 quantitative and dichotomous traits. PLoS Genet. 2013 May; 9(5):e1003520. Zaitlen N, Kraft P, Patterson N, Pasaniuc B, Bhatia G, Pollack S, Price AL. PMID: 23737753; PMCID: PMC3667752.
      View in: PubMed   Mentions: 194     Fields:    Translation:Humans
    126. Analysis of Latino populations from GALA and MEC studies reveals genomic loci with biased local ancestry estimation. Bioinformatics. 2013 Jun 01; 29(11):1407-15. Pasaniuc B, Sankararaman S, Torgerson DG, Gignoux C, Zaitlen N, Eng C, Rodriguez-Cintron W, Chapela R, Ford JG, Avila PC, Rodriguez-Santana J, Chen GK, Le Marchand L, Henderson B, Reich D, Haiman CA, Gonzàlez Burchard E, Halperin E. PMID: 23572411; PMCID: PMC3661056.
      View in: PubMed   Mentions: 30     Fields:    Translation:Humans
    127. Using population admixture to help complete maps of the human genome. Nat Genet. 2013 Apr; 45(4):406-14, 414e1-2. Genovese G, Handsaker RE, Li H, Altemose N, Lindgren AM, Chambert K, Pasaniuc B, Price AL, Reich D, Morton CC, Pollak MR, Wilson JG, McCarroll SA. PMID: 23435088; PMCID: PMC3683849.
      View in: PubMed   Mentions: 41     Fields:    Translation:HumansCells
    128. Informed conditioning on clinical covariates increases power in case-control association studies. PLoS Genet. 2012; 8(11):e1003032. Zaitlen N, Lindström S, Pasaniuc B, Cornelis M, Genovese G, Pollack S, Barton A, Bickeböller H, Bowden DW, Eyre S, Freedman BI, Friedman DJ, Field JK, Groop L, Haugen A, Heinrich J, Henderson BE, Hicks PJ, Hocking LJ, Kolonel LN, Landi MT, Langefeld CD, Le Marchand L, Meister M, Morgan AW, Raji OY, Risch A, Rosenberger A, Scherf D, Steer S, Walshaw M, Waters KM, Wilson AG, Wordsworth P, Zienolddiny S, Tchetgen ET, Haiman C, Hunter DJ, Plenge RM, Worthington J, Christiani DC, Schaumberg DA, Chasman DI, Altshuler D, Voight B, Kraft P, Patterson N, Price AL. PMID: 23144628; PMCID: PMC3493452.
      View in: PubMed   Mentions: 45     Fields:    Translation:Humans
    129. Extremely low-coverage sequencing and imputation increases power for genome-wide association studies. Nat Genet. 2012 May 20; 44(6):631-5. Pasaniuc B, Rohland N, McLaren PJ, Garimella K, Zaitlen N, Li H, Gupta N, Neale BM, Daly MJ, Sklar P, Sullivan PF, Bergen S, Moran JL, Hultman CM, Lichtenstein P, Magnusson P, Purcell SM, Haas DW, Liang L, Sunyaev S, Patterson N, de Bakker PI, Reich D, Price AL. PMID: 22610117; PMCID: PMC3400344.
      View in: PubMed   Mentions: 135     Fields:    Translation:Humans
    130. Analysis of case-control association studies with known risk variants. Bioinformatics. 2012 Jul 01; 28(13):1729-37. Zaitlen N, Pasaniuc B, Patterson N, Pollack S, Voight B, Groop L, Altshuler D, Henderson BE, Kolonel LN, Le Marchand L, Waters K, Haiman CA, Stranger BE, Dermitzakis ET, Kraft P, Price AL. PMID: 22556366; PMCID: PMC3381970.
      View in: PubMed   Mentions: 20     Fields:    Translation:Humans
    131. Fast and accurate inference of local ancestry in Latino populations. Bioinformatics. 2012 May 15; 28(10):1359-67. Baran Y, Pasaniuc B, Sankararaman S, Torgerson DG, Gignoux C, Eng C, Rodriguez-Cintron W, Chapela R, Ford JG, Avila PC, Rodriguez-Santana J, Burchard EG, Halperin E. PMID: 22495753; PMCID: PMC3348558.
      View in: PubMed   Mentions: 141     Fields:    Translation:Humans
    132. Admixture mapping identifies a locus on 6q25 associated with breast cancer risk in US Latinas. Hum Mol Genet. 2012 Apr 15; 21(8):1907-17. Fejerman L, Chen GK, Eng C, Huntsman S, Hu D, Williams A, Pasaniuc B, John EM, Via M, Gignoux C, Ingles S, Monroe KR, Kolonel LN, Torres-Mejía G, Pérez-Stable EJ, Burchard EG, Henderson BE, Haiman CA, Ziv E. PMID: 22228098; PMCID: PMC3313799.
      View in: PubMed   Mentions: 42     Fields:    Translation:HumansCells
    133. Combining effects from rare and common genetic variants in an exome-wide association study of sequence data. BMC Proc. 2011 Nov 29; 5 Suppl 9:S44. Aschard H, Qiu W, Pasaniuc B, Zaitlen N, Cho MH, Carey V. PMID: 22373328; PMCID: PMC3287881.
      View in: PubMed   Mentions: 2  
    134. Genome-wide comparison of African-ancestry populations from CARe and other cohorts reveals signals of natural selection. Am J Hum Genet. 2011 Sep 09; 89(3):368-81. Bhatia G, Patterson N, Pasaniuc B, Zaitlen N, Genovese G, Pollack S, Mallick S, Myers S, Tandon A, Spencer C, Palmer CD, Adeyemo AA, Akylbekova EL, Cupples LA, Divers J, Fornage M, Kao WH, Lange L, Li M, Musani S, Mychaleckyj JC, Ogunniyi A, Papanicolaou G, Rotimi CN, Rotter JI, Ruczinski I, Salako B, Siscovick DS, Tayo BO, Yang Q, McCarroll S, Sabeti P, Lettre G, De Jager P, Hirschhorn J, Zhu X, Cooper R, Reich D, Wilson JG, Price AL. PMID: 21907010; PMCID: PMC3169818.
      View in: PubMed   Mentions: 49     Fields:    Translation:Humans
    135. Inhibition of activated pericentromeric SINE/Alu repeat transcription in senescent human adult stem cells reinstates self-renewal. Cell Cycle. 2011 Sep 01; 10(17):3016-30. Wang J, Geesman GJ, Hostikka SL, Atallah M, Blackwell B, Lee E, Cook PJ, Pasaniuc B, Shariat G, Halperin E, Dobke M, Rosenfeld MG, Jordan IK, Lunyak VV. PMID: 21862875; PMCID: PMC3218602.
      View in: PubMed   Mentions: 61     Fields:    Translation:HumansCells
    136. Genotyping common and rare variation using overlapping pool sequencing. BMC Bioinformatics. 2011; 12 Suppl 6:S2. He D, Zaitlen N, Pasaniuc B, Eskin E, Halperin E. PMID: 21989232; PMCID: PMC3194190.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    137. New approaches to disease mapping in admixed populations. Nat Rev Genet. 2011 Jun 28; 12(8):523-8. Seldin MF, Pasaniuc B, Price AL. PMID: 21709689; PMCID: PMC3142784.
      View in: PubMed   Mentions: 105     Fields:    Translation:Humans
    138. Enhanced statistical tests for GWAS in admixed populations: assessment using African Americans from CARe and a Breast Cancer Consortium. PLoS Genet. 2011 Apr; 7(4):e1001371. Pasaniuc B, Zaitlen N, Lettre G, Chen GK, Tandon A, Kao WH, Ruczinski I, Fornage M, Siscovick DS, Zhu X, Larkin E, Lange LA, Cupples LA, Yang Q, Akylbekova EL, Musani SK, Divers J, Mychaleckyj J, Li M, Papanicolaou GJ, Millikan RC, Ambrosone CB, John EM, Bernstein L, Zheng W, Hu JJ, Ziegler RG, Nyante SJ, Bandera EV, Ingles SA, Press MF, Chanock SJ, Deming SL, Rodriguez-Gil JL, Palmer CD, Buxbaum S, Ekunwe L, Hirschhorn JN, Henderson BE, Myers S, Haiman CA, Reich D, Patterson N, Wilson JG, Price AL. PMID: 21541012; PMCID: PMC3080860.
      View in: PubMed   Mentions: 77     Fields:    Translation:Humans
    139. Accurate estimation of expression levels of homologous genes in RNA-seq experiments. J Comput Biol. 2011 Mar; 18(3):459-68. Pasaniuc B, Zaitlen N, Halperin E. PMID: 21385047.
      View in: PubMed   Mentions: 20     Fields:    Translation:Humans
    140. A generic coalescent-based framework for the selection of a reference panel for imputation. Genet Epidemiol. 2010 Dec; 34(8):773-82. Pasaniuc B, Avinery R, Gur T, Skibola CF, Bracci PM, Halperin E. PMID: 21058333; PMCID: PMC3876740.
      View in: PubMed   Mentions: 18     Fields:    Translation:Humans
    141. Leveraging genetic variability across populations for the identification of causal variants. Am J Hum Genet. 2010 Jan; 86(1):23-33. Zaitlen N, Pasaniuc B, Gur T, Ziv E, Halperin E. PMID: 20085711; PMCID: PMC2801753.
      View in: PubMed   Mentions: 91     Fields:    Translation:Humans
    142. Inference of locus-specific ancestry in closely related populations. Bioinformatics. 2009 Jun 15; 25(12):i213-21. Pasaniuc B, Sankararaman S, Kimmel G, Halperin E. PMID: 19477991; PMCID: PMC2687951.
      View in: PubMed   Mentions: 86     Fields:    Translation:Humans
    143. Genotype error detection using Hidden Markov Models of haplotype diversity. J Comput Biol. 2008 Nov; 15(9):1155-71. Kennedy J, Mandoiu I, Pasaniuc B. PMID: 18973433.
      View in: PubMed   Mentions: 10     Fields:    Translation:Humans
    144. Highly scalable genotype phasing by entropy minimization. IEEE/ACM Trans Comput Biol Bioinform. 2008 Apr-Jun; 5(2):252-61. Gusev A, Mandoiu II, Pasaniuc B. PMID: 18451434.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    145. Highly scalable genotype phasing by entropy minimization. Conf Proc IEEE Eng Med Biol Soc. 2006; 2006:3482-6. Pasaniuc B, Mandoiu I. PMID: 17946566.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
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