Kenneth L Lange

Title(s)Professor, Computational Medicine
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    Title(s)Professor, Human Genetics

    Collapse Research 
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    Modeling, Inference, and Optimization for Genomic and Biomedical Big Data
    NIH R35GM141798Jul 1, 2021 - May 31, 2026
    Role: Principal Investigator
    Training Grant in Genomic Analysis and Interpretation
    NIH T32HG002536Jul 1, 2002 - Jun 30, 2022
    Role: Co-Principal Investigator
    Statistical Methods for Gene Mapping
    NIH R01GM053275Aug 1, 1995 - Mar 31, 2021
    Role: Principal Investigator
    Systems in Integrative Biology
    NIH T32GM008185Jul 1, 1987 - Jun 30, 2023
    Role: Co-Principal Investigator

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. A multivariate Bernoulli model to predict DNaseI hypersensitivity status from haplotype data. Bioinformatics. 2015 Nov 01; 31(21):3514-21. Shi H, Pasaniuc B, Lange KL. PMID: 26139633.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    2. A Brief Survey of Modern Optimization for Statisticians. Int Stat Rev. 2014 Apr 01; 82(1):46-70. Lange K, Chi EC, Zhou H. PMID: 25242858.
      View in: PubMed   Mentions:
    3. MM Algorithms for Geometric and Signomial Programming. Math Program. 2014 Feb 01; 143(1-2):339-356. Lange K, Zhou H. PMID: 24634545.
      View in: PubMed   Mentions:
    4. Mendel: the Swiss army knife of genetic analysis programs. Bioinformatics. 2013 Jun 15; 29(12):1568-70. Lange K, Papp JC, Sinsheimer JS, Sripracha R, Zhou H, Sobel EM. PMID: 23610370.
      View in: PubMed   Mentions: 60     Fields:    Translation:Humans
    5. Extinction models for cancer stem cell therapy. Math Biosci. 2011 Dec; 234(2):132-46. Sehl M, Zhou H, Sinsheimer JS, Lange KL. PMID: 22001354.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansCells
    6. On the Bumpy Road to the Dominant Mode. Scand Stat Theory Appl. 2010 Dec; 37(4):612-631. Zhou H, Lange KL. PMID: 21170287.
      View in: PubMed   Mentions:
    7. Differential destruction of stem cells: implications for targeted cancer stem cell therapy. Cancer Res. 2009 Dec 15; 69(24):9481-9. Sehl ME, Sinsheimer JS, Zhou H, Lange KL. PMID: 19996291.
      View in: PubMed   Mentions: 15     Fields:    Translation:Cells
    8. Accurate stochastic simulation via the step anticipation tau-leaping (SAL) algorithm. J Comput Biol. 2009 Sep; 16(9):1195-208. Sehl M, Alekseyenko AV, Lange KL. PMID: 19772431.
      View in: PubMed   Mentions: 7     Fields:    
    9. Variance component models for X-linked QTLs. Genet Epidemiol. 2006 Jul; 30(5):380-3. Lange K, Sobel E. PMID: 16671110.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    10. Association testing with Mendel. Genet Epidemiol. 2005 Jul; 29(1):36-50. Lange K, Sinsheimer JS, Sobel E. PMID: 15834862.
      View in: PubMed   Mentions: 43     Fields:    Translation:Humans
    11. The pedigree trimming problem. Hum Hered. 2004; 58(2):108-11. Lange K, Sinsheimer JS. PMID: 15711090.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
    12. Palmar hyperhidrosis: evidence of genetic transmission. J Vasc Surg. 2002 Feb; 35(2):382-6. Ro KM, Cantor RM, Lange KL, Ahn SS. PMID: 11854739.
      View in: PubMed   Mentions: 35     Fields:    Translation:Humans
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