Mary Elizabeth Sehl

Title(s)Hs Clinical Professor, Medicine
SchoolMedicine
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    Title(s)Adjunct Professor, Computational Medicine


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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. CRE25-032: Carfilzomib-Induced Thrombotic Microangiopathy in Multiple Myeloma. J Natl Compr Canc Netw. 2025 Mar 28; 23(3.5). Bransky NP, Kathuria-Prakash N, Sehl M. PMID: 40154331.
      View in: PubMed   Mentions:    Fields:    
    2. Decreased but persistent epigenetic age acceleration is associated with changes in T-cell subsets after initiation of highly active antiretroviral therapy in persons living with HIV. Front Bioinform. 2024; 4:1356509. Sehl ME, Breen EC, Shih R, Li F, Zhang J, Langfelder P, Horvath S, Bream JH, Duggal P, Martinson J, Wolinsky SM, Martinez-Maza O, Ramirez CM, Jamieson BD. PMID: 38855141; PMCID: PMC11157435.
      View in: PubMed   Mentions:
    3. Effects of highly active antiretroviral therapy initiation on epigenomic DNA methylation in persons living with HIV. Front Bioinform. 2024; 4:1357889. Zhang J, Sehl ME, Shih R, Breen EC, Li F, Lu AT, Bream JH, Duggal P, Martinson J, Wolinsky SM, Martinez-Maza O, Ramirez CM, Horvath S, Jamieson BD. PMID: 38855142; PMCID: PMC11157437.
      View in: PubMed   Mentions: 1  
    4. Acute pulmonary injury in hematology patients supported with pathogen-reduced and conventional platelet components. Blood Adv. 2024 05 14; 8(9):2290-2299. Wheeler AP, Snyder EL, Refaai M, Cohn CS, Poisson J, Fontaine M, Sehl M, Nooka AK, Uhl L, Spinella PC, Fenelus M, Liles D, Coyle T, Becker J, Jeng M, Gehrie EA, Spencer BR, Young P, Johnson A, O'Brien JJ, Schiller GJ, Roback JD, Malynn E, Jackups R, Avecilla ST, Liu K, Bentow S, Varrone J, Benjamin RJ, Corash LM. PMID: 38447116; PMCID: PMC11116994.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    5. Inhibition of Ephrin B2 Reverse Signaling Abolishes Multiple Myeloma Pathogenesis. Cancer Res. 2024 Mar 15; 84(6):919-934. Sasine JP, Kozlova NY, Valicente L, Dukov J, Tran DH, Himburg HA, Kumar S, Khorsandi S, Chan A, Grohe S, Li M, Kan J, Sehl ME, Schiller GJ, Reinhardt B, Singh BK, Ho R, Yue P, Pasquale EB, Chute JP. PMID: 38231476; PMCID: PMC10940855.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimalsCells
    6. Erratum: Accelerated aging with HIV begins at the time of initial HIV infection. iScience. 2023 Aug 18; 26(8):107381. Breen EC, Sehl ME, Shih R, Langfelder P, Wang R, Horvath S, Bream JH, Duggal P, Martinson J, Wolinsky SM, Martínez-Maza O, Ramirez CM, Jamieson BD. PMID: 37520728; PMCID: PMC10371831.
      View in: PubMed   Mentions: 1  
    7. Accelerated aging with HIV begins at the time of initial HIV infection. iScience. 2022 Jul 15; 25(7):104488. Breen EC, Sehl ME, Shih R, Langfelder P, Wang R, Horvath S, Bream JH, Duggal P, Martinson J, Wolinsky SM, Martínez-Maza O, Ramirez CM, Jamieson BD. PMID: 35880029; PMCID: PMC9308149.
      View in: PubMed   Mentions: 23  
    8. Comparative risk of pulmonary adverse events with transfusion of pathogen reduced and conventional platelet components. Transfusion. 2022 07; 62(7):1365-1376. Snyder EL, Wheeler AP, Refaai M, Cohn CS, Poisson J, Fontaine M, Sehl M, Nooka AK, Uhl L, Spinella P, Fenelus M, Liles D, Coyle T, Becker J, Jeng M, Gehrie EA, Spencer BR, Young P, Johnson A, O'Brien JJ, Schiller GJ, Roback JD, Malynn E, Jackups R, Avecilla ST, Lin JS, Liu K, Bentow S, Peng HL, Varrone J, Benjamin RJ, Corash LM. PMID: 35748490; PMCID: PMC9544211.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
    9. DNA Methylation, Aging, and Cancer Risk: A Mini-Review. Front Bioinform. 2022; 2:847629. Chen L, Ganz PA, Sehl ME. PMID: 36304336; PMCID: PMC9580889.
      View in: PubMed   Mentions: 15  
    10. The impact of reproductive factors on DNA methylation-based telomere length in healthy breast tissue. NPJ Breast Cancer. 2022 Apr 13; 8(1):48. Sehl ME, Henry JE, Storniolo AM, Horvath S, Ganz PA. PMID: 35418123; PMCID: PMC9007943.
      View in: PubMed   Mentions: 3  
    11. Increased Rate of Epigenetic Aging in Men Living With HIV Prior to Treatment. Front Genet. 2021; 12:796547. Sehl ME, Breen EC, Shih R, Chen L, Wang R, Horvath S, Bream JH, Duggal P, Martinson J, Wolinsky SM, Martinez-Maza O, Ramirez CM, Jamieson BD. PMID: 35295196; PMCID: PMC8919029.
      View in: PubMed   Mentions: 11  
    12. Computational tools for assessing gene therapy under branching process models of mutation. Bull Math Biol. 2021 12 06; 84(1):15. Stutz TC, Sinsheimer JS, Sehl M, Xu J. PMID: 34870755.
      View in: PubMed   Mentions:    Fields:    
    13. An examination of school reopening strategies during the SARS-CoV-2 pandemic. PLoS One. 2021; 16(5):e0251242. Landeros A, Ji X, Lange K, Stutz TC, Xu J, Sehl ME, Sinsheimer JS. PMID: 34014947; PMCID: PMC8136712.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansPHPublic Health
    14. The Effects of Lifetime Estrogen Exposure on Breast Epigenetic Age. Cancer Epidemiol Biomarkers Prev. 2021 06; 30(6):1241-1249. Sehl ME, Henry JE, Storniolo AM, Horvath S, Ganz PA. PMID: 33771849; PMCID: PMC8172523.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansCells
    15. An examination of school reopening strategies during the SARS-CoV-2 pandemic. medRxiv. 2021 Mar 19. Landeros A, Ji X, Lange K, Stutz TC, Xu J, Sehl ME, Sinsheimer JS. PMID: 32793918; PMCID: PMC7418733.
      View in: PubMed   Mentions:
    16. Stochastic simulation algorithms for Interacting Particle Systems. PLoS One. 2021; 16(3):e0247046. Stutz TC, Landeros A, Xu J, Sinsheimer JS, Sehl M, Lange K. PMID: 33651796; PMCID: PMC7924777.
      View in: PubMed   Mentions:    Fields:    
    17. The Effects of Anti-retroviral Therapy on Epigenetic Age Acceleration Observed in HIV-1-infected Adults. Pathog Immun. 2020; 5(1):291-311. Sehl ME, Rickabaugh TM, Shih R, Martinez-Maza O, Horvath S, Ramirez CM, Jamieson BD. PMID: 33501399; PMCID: PMC7815056.
      View in: PubMed   Mentions: 17  
    18. The acute effects of adjuvant radiation and chemotherapy on peripheral blood epigenetic age in early stage breast cancer patients. NPJ Breast Cancer. 2020; 6:23. Sehl ME, Carroll JE, Horvath S, Bower JE. PMID: 32566744; PMCID: PMC7293278.
      View in: PubMed   Mentions: 37  
    19. BioSimulator.jl: Stochastic simulation in Julia. Comput Methods Programs Biomed. 2018 Dec; 167:23-35. Landeros A, Stutz T, Keys KL, Alekseyenko A, Sinsheimer JS, Lange K, Sehl ME. PMID: 30501857; PMCID: PMC6388686.
      View in: PubMed   Mentions: 5     Fields:    
    20. Potential Mechanisms of Age Acceleration Caused by Estrogen Deprivation: Do Endocrine Therapies Carry the Same Risks? JNCI Cancer Spectr. 2018 Jul; 2(3):pky035. Sehl ME, Ganz PA. PMID: 31360862; PMCID: PMC6649786.
      View in: PubMed   Mentions: 10     Fields:    
    21. Modeling of Interactions between Cancer Stem Cells and their Microenvironment: Predicting Clinical Response. Methods Mol Biol. 2018; 1711:333-349. Sehl ME, Wicha MS. PMID: 29344897; PMCID: PMC6322404.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimalsCells
    22. Decreased levels of the serum inflammatory biomarkers, sGP130, IL-6, sCRP and BAFF, are associated with increased likelihood of AIDS related Kaposi's sarcoma in men who have sex with men. Cancer Res Front. 2018; 4(1):45-59. Bolanos R, Martinez-Maza O, Zhang ZF, Hussain S, Sehl M, Sinsheimer JS, D'Souza G, Jenkins F, Wolinsky S, Detels R. PMID: 33521162; PMCID: PMC7845762.
      View in: PubMed   Mentions: 2  
    23. DNA methylation age is elevated in breast tissue of healthy women. Breast Cancer Res Treat. 2017 Jul; 164(1):209-219. Sehl ME, Henry JE, Storniolo AM, Ganz PA, Horvath S. PMID: 28364215; PMCID: PMC5487725.
      View in: PubMed   Mentions: 39     Fields:    Translation:HumansCells
    24. Disease drivers of aging. Ann N Y Acad Sci. 2016 12; 1386(1):45-68. Hodes RJ, Sierra F, Austad SN, Epel E, Neigh GN, Erlandson KM, Schafer MJ, LeBrasseur NK, Wiley C, Campisi J, Sehl ME, Scalia R, Eguchi S, Kasinath BS, Halter JB, Cohen HJ, Demark-Wahnefried W, Ahles TA, Barzilai N, Hurria A, Hunt PW. PMID: 27943360; PMCID: PMC5373660.
      View in: PubMed   Mentions: 62     Fields:    Translation:Humans
    25. Modeling of Cancer Stem Cell State Transitions Predicts Therapeutic Response. PLoS One. 2015; 10(9):e0135797. Sehl ME, Shimada M, Landeros A, Lange K, Wicha MS. PMID: 26397099; PMCID: PMC4580445.
      View in: PubMed   Mentions: 21     Fields:    Translation:HumansCells
    26. Successful management of chronic gastrointestinal hemorrhage using bevacizumab in the setting of hereditary hemorrhagic telangiectasia. Am J Hematol. 2015 Jun; 90(6):561-3. Sehl ME, M Gruber T, McWilliams JP, Marder VJ. PMID: 25677911; PMCID: PMC5143277.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    27. Acceleration of age-associated methylation patterns in HIV-1-infected adults. PLoS One. 2015; 10(3):e0119201. Rickabaugh TM, Baxter RM, Sehl M, Sinsheimer JS, Hultin PM, Hultin LE, Quach A, Martínez-Maza O, Horvath S, Vilain E, Jamieson BD. PMID: 25807146; PMCID: PMC4373843.
      View in: PubMed   Mentions: 72     Fields:    Translation:HumansCells
    28. Dynamics of HSPC repopulation in nonhuman primates revealed by a decade-long clonal-tracking study. Cell Stem Cell. 2014 Apr 03; 14(4):473-85. Kim S, Kim N, Presson AP, Metzger ME, Bonifacino AC, Sehl M, Chow SA, Crooks GM, Dunbar CE, An DS, Donahue RE, Chen IS. PMID: 24702996; PMCID: PMC4009343.
      View in: PubMed   Mentions: 56     Fields:    Translation:AnimalsCells
    29. Long-term outcomes among African-American and white women with breast cancer: what is the impact of comorbidity? J Geriatr Oncol. 2014 Jul; 5(3):266-75. Izano M, Satariano WA, Tammemagi MC, Ragland D, Moore DH, Allen E, Naeim A, Sehl ME, Hiatt RA, Kerlikowske K, Sofrygin O, Braithwaite D. PMID: 24613574.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    30. Determining duration of HER2-targeted therapy using stem cell extinction models. PLoS One. 2012; 7(12):e46613. Riley L, Zhou H, Lange K, Sinsheimer JS, Sehl ME. PMID: 23284608; PMCID: PMC3532453.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    31. Serum levels of the chemokine CXCL13, genetic variation in CXCL13 and its receptor CXCR5, and HIV-associated non-hodgkin B-cell lymphoma risk. Cancer Epidemiol Biomarkers Prev. 2013 Feb; 22(2):295-307. Hussain SK, Zhu W, Chang SC, Breen EC, Vendrame E, Magpantay L, Widney D, Conn D, Sehl M, Jacobson LP, Bream JH, Wolinsky S, Rinaldo CR, Ambinder RF, Detels R, Zhang ZF, Martínez-Maza O. PMID: 23250934; PMCID: PMC3703445.
      View in: PubMed   Mentions: 35     Fields:    Translation:Humans
    32. Decline in physical functioning in first 2 years after breast cancer diagnosis predicts 10-year survival in older women. J Cancer Surviv. 2013 Mar; 7(1):20-31. Sehl M, Lu X, Silliman R, Ganz PA. PMID: 23232922; PMCID: PMC3568656.
      View in: PubMed   Mentions: 54     Fields:    Translation:Humans
    33. Stem cell niche dynamics: from homeostasis to carcinogenesis. Stem Cells Int. 2012; 2012:367567. Tieu KS, Tieu RS, Martinez-Agosto JA, Sehl ME. PMID: 22448171; PMCID: PMC3289927.
      View in: PubMed   Mentions: 7  
    34. Extinction models for cancer stem cell therapy. Math Biosci. 2011 Dec; 234(2):132-46. Sehl M, Zhou H, Sinsheimer JS, Lange KL. PMID: 22001354; PMCID: PMC3312607.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansCells
    35. Epigenetic predictor of age. PLoS One. 2011; 6(6):e14821. Bocklandt S, Lin W, Sehl ME, Sánchez FJ, Sinsheimer JS, Horvath S, Vilain E. PMID: 21731603; PMCID: PMC3120753.
      View in: PubMed   Mentions: 431     Fields:    Translation:HumansCells
    36. Association screening of common and rare genetic variants by penalized regression. Bioinformatics. 2010 Oct 01; 26(19):2375-82. Zhou H, Sehl ME, Sinsheimer JS, Lange K. PMID: 20693321; PMCID: PMC3025646.
      View in: PubMed   Mentions: 71     Fields:    Translation:Humans
    37. A Poisson model for random multigraphs. Bioinformatics. 2010 Aug 15; 26(16):2004-11. Ranola JM, Ahn S, Sehl M, Smith DJ, Lange K. PMID: 20554690; PMCID: PMC3025746.
      View in: PubMed   Mentions: 6     Fields:    
    38. Differential destruction of stem cells: implications for targeted cancer stem cell therapy. Cancer Res. 2009 Dec 15; 69(24):9481-9. Sehl ME, Sinsheimer JS, Zhou H, Lange KL. PMID: 19996291; PMCID: PMC2844253.
      View in: PubMed   Mentions: 17     Fields:    
    39. Accurate stochastic simulation via the step anticipation tau-leaping (SAL) algorithm. J Comput Biol. 2009 Sep; 16(9):1195-208. Sehl M, Alekseyenko AV, Lange KL. PMID: 19772431; PMCID: PMC3148118.
      View in: PubMed   Mentions: 7     Fields:    
    40. Sex steroid metabolism polymorphisms and mammographic density in pre- and early perimenopausal women. Breast Cancer Res. 2009; 11(4):R51. Crandall CJ, Sehl ME, Crawford SL, Gold EB, Habel LA, Butler LM, Sowers MR, Greendale GA, Sinsheimer JS. PMID: 19630952; PMCID: PMC2750112.
      View in: PubMed   Mentions: 11     Fields:    Translation:Humans
    41. Associations between single nucleotide polymorphisms in double-stranded DNA repair pathway genes and familial breast cancer. Clin Cancer Res. 2009 Mar 15; 15(6):2192-203. Sehl ME, Langer LR, Papp JC, Kwan L, Seldon JL, Arellano G, Reiss J, Reed EF, Dandekar S, Korin Y, Sinsheimer JS, Zhang ZF, Ganz PA. PMID: 19276285; PMCID: PMC2778342.
      View in: PubMed   Mentions: 16     Fields:    
    42. Attribution of functional limitation to cancer decreases in the year following breast cancer diagnosis in older patients. Crit Rev Oncol Hematol. 2009 Jul; 71(1):62-9. Sehl ME, Satariano WA, Ragland DR, Reuben DB, Naeim A. PMID: 19081266; PMCID: PMC2753256.
      View in: PubMed   Mentions: 4     Fields:    
    43. Barriers in the management of glucocorticoid-induced osteoporosis. Arthritis Rheum. 2007 Feb 15; 57(1):140-6. Guzman-Clark JR, Fang MA, Sehl ME, Traylor L, Hahn TJ. PMID: 17266078.
      View in: PubMed   Mentions: 21     Fields:    Translation:Humans
    44. Physiologic aspects of aging: impact on cancer management and decision making, part II. Cancer J. 2005 Nov-Dec; 11(6):461-73. Sehl M, Sawhney R, Naeim A. PMID: 16393480.
      View in: PubMed   Mentions: 56     Fields:    Translation:Humans
    45. Physiologic aspects of aging: impact on cancer management and decision making, part I. Cancer J. 2005 Nov-Dec; 11(6):449-60. Sawhney R, Sehl M, Naeim A. PMID: 16393479.
      View in: PubMed   Mentions: 60     Fields:    Translation:Humans
    46. Reproduction and survival in Mediterranean fruit flies: a "protein and energy" free radical model of aging. Biogerontology. 2003; 4(6):387-95. Butov AA, Carey JR, Volkov MA, Sehl ME, Yashin AI. PMID: 14739710.
      View in: PubMed   Mentions:    Fields:    Translation:Animals
    47. A model of accelerated aging induced by 5-bromodeoxyuridine. Biogerontology. 2002; 3(3):175-82. Butov AA, Volkov MA, Anisimov VN, Sehl ME, Yashin AI. PMID: 12075136.
      View in: PubMed   Mentions:    Fields:    Translation:Animals
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