Gay M Crooks

Title(s)Professor, Pathology and Laboratory Medicine
SchoolMedicine
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    Title(s)Professor, Orthopaedic Surgery

    Title(s)Professor, Pediatrics


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    Dr. Gay M. Crooks holds the Rebecca Smith Chair in Molecular and Cellular Pathology.

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    Tumor Cell Biology Training Program
    NIH/NCI T32CA009056Aug 1, 2023 - Jul 31, 2028
    Role: Co-Principal Investigator
    Description: This training program’s goal is to span the disciplines of pathology, oncology, molecular biology, engineering, chemistry, bioinformatics and biomathematics related to modern medicine and biomedical research, in order to train the next generation of transdisciplinary scientists.
    The role of BCL11B in T lineage fate during human thymopoiesis and pluripotent stem cell differentiation
    NIH 1 R01 AI176249-01Jul 1, 2023 - Jun 30, 2028
    Role: Principal Investigator
    Description: The studies proposed are designed to further our understanding of how BCL11B induces T cell specification and commitment, and to apply these insights to the setting of T cell differentiation from human pluripotent stem cells (PSCs)
    Engineering pluripotent stem cells for universally available, off-the-shelf T cell therapies
    California Institute for Regenerative Medicine (CIRM) DISC0-14422Jul 1, 2023 - Jun 30, 2026
    Role: Principal Investigator
    Description: The overall objective of this proposal is to uncover the critical elements required to generate a universal source of off-the-shelf, mature, conventional CART cells from induced Pluripotent Stem Cells (iPSCs). Our studies will focus on the need to achieve normal differentiation of mature CART cells in the absence of TCR expression
    The Role of Lymphatic Endothelium in the Developing Thymus
    NIH/NIAID 1 R01 AI173496-01A1Jun 16, 2023 - May 31, 2028
    Role: Principal Investigator
    Description: The studies proposed will use the unique window of the murine neonatal period to define the factors that control the growth and regression of the lymphatic endothelial cells (LECs) in the thymus, as well as the role of LECs in the dramatic concurrent changes seen in the other thymic compartments.
    Targeting alternative splicing for TCR discovery in small cell carcinomas
    NIH U01CA233074Sep 21, 2018 - Aug 31, 2023
    Role: Co-Principal Investigator
    “Inducing tolerance after VCA through Adoptive Therapy of Thymic Regulatory T cells”
    The Connie Frank and Evan Thompson Program for Collaborative Restorative Transplantation Research Jul 1, 2018 - Jun 30, 2022
    Role: Principal Investigator
    Description: These studies will use a combination of murine and human ATO models to identify the optimal combination of factors for Treg production.
    Discovery and manipulation of mesenchymal signals for thymic rejuvenation
    NIH R01AG049753Jun 1, 2016 - May 31, 2021
    Role: Principal Investigator

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Lentiviral vectors for precise expression to treat X-linked lymphoproliferative disease. Mol Ther Methods Clin Dev. 2024 Dec 12; 32(4):101323. Ayoub PG, Gensheimer J, Lathrop L, Juett C, Quintos J, Tam K, Reid J, Ma F, Tam C, McAuley GE, Brown D, Wu X, Zhang R, Bradford K, Hollis RP, Crooks GM, Kohn DB. PMID: 39309261; PMCID: PMC11415656.
      View in: PubMed   Mentions:
    2. MYCT1 controls environmental sensing in human haematopoietic stem cells. Nature. 2024 Jun; 630(8016):412-420. Aguadé-Gorgorió J, Jami-Alahmadi Y, Calvanese V, Kardouh M, Fares I, Johnson H, Rezek V, Ma F, Magnusson M, Wang Y, Shin JE, Nance KJ, Goodridge HS, Liebscher S, Schenke-Layland K, Crooks GM, Wohlschlegel JA, Mikkola HKA. PMID: 38839950; PMCID: PMC11168926.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimalsCells
    3. Exonic knockout and knockin gene editing in hematopoietic stem and progenitor cells rescues RAG1 immunodeficiency. Sci Transl Med. 2024 Feb 07; 16(733):eadh8162. Castiello MC, Brandas C, Ferrari S, Porcellini S, Sacchetti N, Canarutto D, Draghici E, Merelli I, Barcella M, Pelosi G, Vavassori V, Varesi A, Jacob A, Scala S, Basso Ricci L, Paulis M, Strina D, Di Verniere M, Sergi Sergi L, Serafini M, Holland SM, Bergerson JRE, De Ravin SS, Malech HL, Pala F, Bosticardo M, Brombin C, Cugnata F, Calzoni E, Crooks GM, Notarangelo LD, Genovese P, Naldini L, Villa A. PMID: 38324638; PMCID: PMC11149094.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimalsCells
    4. Generation of antigen-specific mature T cells from RAG1-/-RAG2-/-B2M-/- stem cells by engineering their microenvironment. Nat Biomed Eng. 2024 Apr; 8(4):461-478. Chang PC, Yuan X, Zampieri A, Towns C, Yoo SP, Engstrom C, Tsai S, Robles CR, Zhu Y, Lopez S, Montel-Hagen A, Seet CS, Crooks GM. PMID: 38062131; PMCID: PMC11087257.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    5. IRIS: Discovery of cancer immunotherapy targets arising from pre-mRNA alternative splicing. Proc Natl Acad Sci U S A. 2023 05 23; 120(21):e2221116120. Pan Y, Phillips JW, Zhang BD, Noguchi M, Kutschera E, McLaughlin J, Nesterenko PA, Mao Z, Bangayan NJ, Wang R, Tran W, Yang HT, Wang Y, Xu Y, Obusan MB, Cheng D, Lee AH, Kadash-Edmondson KE, Champhekar A, Puig-Saus C, Ribas A, Prins RM, Seet CS, Crooks GM, Witte ON, Xing Y. PMID: 37192158; PMCID: PMC10214192.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansCells
    6. Layered immune system development in mice and humans. Immunol Rev. 2023 05; 315(1):5-10. Dorshkind K, Crooks G. PMID: 36960956.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimals
    7. Human T cell generation is restored in CD3δ severe combined immunodeficiency through adenine base editing. Cell. 2023 03 30; 186(7):1398-1416.e23. McAuley GE, Yiu G, Chang PC, Newby GA, Campo-Fernandez B, Fitz-Gibbon ST, Wu X, Kang SL, Garibay A, Butler J, Christian V, Wong RL, Everette KA, Azzun A, Gelfer H, Seet CS, Narendran A, Murguia-Favela L, Romero Z, Wright N, Liu DR, Crooks GM, Kohn DB. PMID: 36944331; PMCID: PMC10876291.
      View in: PubMed   Mentions: 22     Fields:    Translation:HumansAnimalsCells
    8. Strength of CAR signaling determines T cell versus ILC differentiation from pluripotent stem cells. Cell Rep. 2023 03 28; 42(3):112241. Li S, Wang CS, Montel-Hagen A, Chen HC, Lopez S, Zhou O, Dai K, Tsai S, Satyadi W, Botero C, Wong C, Casero D, Crooks GM, Seet CS. PMID: 36906850; PMCID: PMC10315155.
      View in: PubMed   Mentions: 4     Fields:    Translation:Cells
    9. Purine nucleoside phosphorylase enables dual metabolic checkpoints that prevent T cell immunodeficiency and TLR7-associated autoimmunity. J Clin Invest. 2022 08 15; 132(16). Abt ER, Rashid K, Le TM, Li S, Lee HR, Lok V, Li L, Creech AL, Labora AN, Mandl HK, Lam AK, Cho A, Rezek V, Wu N, Abril-Rodriguez G, Rosser EW, Mittelman SD, Hugo W, Mehrling T, Bantia S, Ribas A, Donahue TR, Crooks GM, Wu TT, Radu CG. PMID: 35653193; PMCID: PMC9374381.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansAnimalsCells
    10. Physical and in silico immunopeptidomic profiling of a cancer antigen prostatic acid phosphatase reveals targets enabling TCR isolation. Proc Natl Acad Sci U S A. 2022 08 02; 119(31):e2203410119. Mao Z, Nesterenko PA, McLaughlin J, Deng W, Burton Sojo G, Cheng D, Noguchi M, Chour W, DeLucia DC, Finton KA, Qin Y, Obusan MB, Tran W, Wang L, Bangayan NJ, Ta L, Chen CC, Seet CS, Crooks GM, Phillips JW, Heath JR, Strong RK, Lee JK, Wohlschlegel JA, Witte ON. PMID: 35878026; PMCID: PMC9351518.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    11. 3D-organoid culture supports differentiation of human CAR+ iPSCs into highly functional CAR T cells. Cell Stem Cell. 2022 Apr 07; 29(4):651-653. Wang Z, McWilliams-Koeppen HP, Reza H, Ostberg JR, Chen W, Wang X, Huynh C, Vyas V, Chang WC, Starr R, Wagner JR, Aguilar B, Yang X, Wu X, Wang J, Chen W, Koelker-Wolfe E, Seet CS, Montel-Hagen A, Crooks GM, Forman SJ, Brown CE. PMID: 35395190.
      View in: PubMed   Mentions: 3     Fields:    
    12. Generation of Artificial Thymic Organoids from Human and Murine Hematopoietic Stem and Progenitor Cells. Curr Protoc. 2022 Apr; 2(4):e403. Montel-Hagen A, Tsai S, Seet CS, Crooks GM. PMID: 35384408.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimalsCells
    13. 3D-organoid culture supports differentiation of human CAR+ iPSCs into highly functional CAR T cells. Cell Stem Cell. 2022 04 07; 29(4):515-527.e8. Wang Z, McWilliams-Koeppen HP, Reza H, Ostberg JR, Chen W, Wang X, Huynh C, Vyas V, Chang WC, Starr R, Wagner JR, Aguilar B, Yang X, Wu X, Wang J, Chen W, Koelker-Wolfe E, Seet CS, Montel-Hagen A, Crooks GM, Forman SJ, Brown CE. PMID: 35278370; PMCID: PMC9119152.
      View in: PubMed   Mentions: 49     Fields:    Translation:HumansAnimalsCells
    14. High Interferon Signature Leads to Increased STAT1/3/5 Phosphorylation in PBMCs From SLE Patients by Single Cell Mass Cytometry. Front Immunol. 2022; 13:833636. Yiu G, Rasmussen TK, Tsai BL, Diep VK, Haddon DJ, Tsoi J, Miller GD, Comin-Anduix B, Deleuran B, Crooks GM, Utz PJ. PMID: 35185925; PMCID: PMC8851522.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCells
    15. Development of allogeneic HSC-engineered iNKT cells for off-the-shelf cancer immunotherapy. Cell Rep Med. 2021 11 16; 2(11):100449. Li YR, Zhou Y, Kim YJ, Zhu Y, Ma F, Yu J, Wang YC, Chen X, Li Z, Zeng S, Wang X, Lee D, Ku J, Tsao T, Hardoy C, Huang J, Cheng D, Montel-Hagen A, Seet CS, Crooks GM, Larson SM, Sasine JP, Wang X, Pellegrini M, Ribas A, Kohn DB, Witte O, Wang P, Yang L. PMID: 34841295; PMCID: PMC8607011.
      View in: PubMed   Mentions: 43     Fields:    Translation:HumansAnimalsCells
    16. The Metabolic Landscape of Thymic T Cell Development In Vivo and In Vitro. Front Immunol. 2021; 12:716661. Sun V, Sharpley M, Kaczor-Urbanowicz KE, Chang P, Montel-Hagen A, Lopez S, Zampieri A, Zhu Y, de Barros SC, Parekh C, Casero D, Banerjee U, Crooks GM. PMID: 34394122; PMCID: PMC8355594.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansAnimalsCells
    17. Correction to: Gene Editing Rescues in Vitro T Cell Development of RAG2-Deficient Induced Pluripotent Stem Cells in an Artificial Thymic Organoid System. J Clin Immunol. 2021 Jul; 41(5):863. Gardner CL, Pavel-Dinu M, Dobbs K, Bosticardo M, Reardon PK, Lack J, DeRavin SS, Le K, Bello E, Pala F, Delmonte OM, Malech H, Montel-Hagen A, Crooks G, Acuto O, Porteus MH, Notarangelo LD. PMID: 33821398.
      View in: PubMed   Mentions: 1     Fields:    
    18. Autologous Ex Vivo Lentiviral Gene Therapy for Adenosine Deaminase Deficiency. N Engl J Med. 2021 05 27; 384(21):2002-2013. Kohn DB, Booth C, Shaw KL, Xu-Bayford J, Garabedian E, Trevisan V, Carbonaro-Sarracino DA, Soni K, Terrazas D, Snell K, Ikeda A, Leon-Rico D, Moore TB, Buckland KF, Shah AJ, Gilmour KC, De Oliveira S, Rivat C, Crooks GM, Izotova N, Tse J, Adams S, Shupien S, Ricketts H, Davila A, Uzowuru C, Icreverzi A, Barman P, Campo Fernandez B, Hollis RP, Coronel M, Yu A, Chun KM, Casas CE, Zhang R, Arduini S, Lynn F, Kudari M, Spezzi A, Zahn M, Heimke R, Labik I, Parrott R, Buckley RH, Reeves L, Cornetta K, Sokolic R, Hershfield M, Schmidt M, Candotti F, Malech HL, Thrasher AJ, Gaspar HB. PMID: 33974366; PMCID: PMC8240285.
      View in: PubMed   Mentions: 74     Fields:    Translation:HumansCellsCTClinical Trials
    19. Gene Editing Rescues In vitro T Cell Development of RAG2-Deficient Induced Pluripotent Stem Cells in an Artificial Thymic Organoid System. J Clin Immunol. 2021 07; 41(5):852-862. Gardner CL, Pavel-Dinu M, Dobbs K, Bosticardo M, Reardon PK, Lack J, DeRavin SS, Le K, Bello E, Pala F, Delmonte OM, Malech H, Montel-Hagan A, Crooks G, Acuto O, Porteus MH, Notarangelo LD. PMID: 33650026; PMCID: PMC8254788.
      View in: PubMed   Mentions: 23     Fields:    Translation:HumansAnimalsCells
    20. Nidogen-1 Mitigates Ischemia and Promotes Tissue Survival and Regeneration. Adv Sci (Weinh). 2021 Feb; 8(4):2002500. Zbinden A, Layland SL, Urbanczyk M, Carvajal Berrio DA, Marzi J, Zauner M, Hammerschmidt A, Brauchle EM, Sudrow K, Fink S, Templin M, Liebscher S, Klein G, Deb A, Duffy GP, Crooks GM, Eble JA, Mikkola HKA, Nsair A, Seifert M, Schenke-Layland K. PMID: 33643791; PMCID: PMC7887579.
      View in: PubMed   Mentions: 13     Fields:    
    21. In Vitro Recapitulation of Murine Thymopoiesis from Single Hematopoietic Stem Cells. Cell Rep. 2020 10 27; 33(4):108320. Montel-Hagen A, Sun V, Casero D, Tsai S, Zampieri A, Jackson N, Li S, Lopez S, Zhu Y, Chick B, He C, de Barros SC, Seet CS, Crooks GM. PMID: 33113379; PMCID: PMC7727762.
      View in: PubMed   Mentions: 10     Fields:    Translation:AnimalsCells
    22. Pleiotropic Roles of VEGF in the Microenvironment of the Developing Thymus. J Immunol. 2020 11 01; 205(9):2423-2436. de Barros SC, Suterwala BT, He C, Ge S, Chick B, Blumberg GK, Kim K, Klein S, Zhu Y, Wang X, Casero D, Crooks GM. PMID: 32989093; PMCID: PMC7679052.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    23. Artificial thymic organoids represent a reliable tool to study T-cell differentiation in patients with severe T-cell lymphopenia. Blood Adv. 2020 06 23; 4(12):2611-2616. Bosticardo M, Pala F, Calzoni E, Delmonte OM, Dobbs K, Gardner CL, Sacchetti N, Kawai T, Garabedian EK, Draper D, Bergerson JRE, DeRavin SS, Freeman AF, Güngör T, Hartog N, Holland SM, Kohn DB, Malech HL, Markert ML, Weinacht KG, Villa A, Seet CS, Montel-Hagen A, Crooks GM, Notarangelo LD. PMID: 32556283; PMCID: PMC7322962.
      View in: PubMed   Mentions: 49     Fields:    Translation:HumansCells
    24. MLLT3 governs human haematopoietic stem-cell self-renewal and engraftment. Nature. 2019 12; 576(7786):281-286. Calvanese V, Nguyen AT, Bolan TJ, Vavilina A, Su T, Lee LK, Wang Y, Lay FD, Magnusson M, Crooks GM, Kurdistani SK, Mikkola HKA. PMID: 31776511; PMCID: PMC7278275.
      View in: PubMed   Mentions: 65     Fields:    Translation:HumansAnimalsCells
    25. Development of Hematopoietic Stem Cell-Engineered Invariant Natural Killer T Cell Therapy for Cancer. Cell Stem Cell. 2019 10 03; 25(4):542-557.e9. Zhu Y, Smith DJ, Zhou Y, Li YR, Yu J, Lee D, Wang YC, Di Biase S, Wang X, Hardoy C, Ku J, Tsao T, Lin LJ, Pham AT, Moon H, McLaughlin J, Cheng D, Hollis RP, Campo-Fernandez B, Urbinati F, Wei L, Pang L, Rezek V, Berent-Maoz B, Macabali MH, Gjertson D, Wang X, Galic Z, Kitchen SG, An DS, Hu-Lieskovan S, Kaplan-Lefko PJ, De Oliveira SN, Seet CS, Larson SM, Forman SJ, Heath JR, Zack JA, Crooks GM, Radu CG, Ribas A, Kohn DB, Witte ON, Yang L. PMID: 31495780; PMCID: PMC7018522.
      View in: PubMed   Mentions: 34     Fields:    Translation:HumansAnimalsCells
    26. Stimulation of Hair Growth by Small Molecules that Activate Autophagy. Cell Rep. 2019 06 18; 27(12):3413-3421.e3. Chai M, Jiang M, Vergnes L, Fu X, de Barros SC, Doan NB, Huang W, Chu J, Jiao J, Herschman H, Crooks GM, Reue K, Huang J. PMID: 31216464.
      View in: PubMed   Mentions: 52     Fields:    Translation:AnimalsCells
    27. Introduction. Exp Hematol. 2019 03; 71:1-2. Crooks GM, Eaves C. PMID: 30769021.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    28. Organoid-Induced Differentiation of Conventional T Cells from Human Pluripotent Stem Cells. Cell Stem Cell. 2019 03 07; 24(3):376-389.e8. Montel-Hagen A, Seet CS, Li S, Chick B, Zhu Y, Chang P, Tsai S, Sun V, Lopez S, Chen HC, He C, Chin CJ, Casero D, Crooks GM. PMID: 30661959; PMCID: PMC6687310.
      View in: PubMed   Mentions: 91     Fields:    Translation:HumansAnimalsCells
    29. From pluripotent stem cells to T cells. Exp Hematol. 2019 03; 71:24-31. Montel-Hagen A, Crooks GM. PMID: 30590093.
      View in: PubMed   Mentions: 23     Fields:    Translation:HumansAnimalsCells
    30. IND-Enabling Studies for a Clinical Trial to Genetically Program a Persistent Cancer-Targeted Immune System. Clin Cancer Res. 2019 02 01; 25(3):1000-1011. Puig-Saus C, Parisi G, Garcia-Diaz A, Krystofinski PE, Sandoval S, Zhang R, Champhekar AS, McCabe J, Cheung-Lau GC, Truong NA, Vega-Crespo A, Komenan MDS, Pang J, Macabali MH, Saco JD, Goodwin JL, Bolon B, Seet CS, Montel-Hagen A, Crooks GM, Hollis RP, Campo-Fernandez B, Bischof D, Cornetta K, Gschweng EH, Adelson C, Nguyen A, Yang L, Witte ON, Baltimore D, Comin-Anduix B, Kohn DB, Wang X, Cabrera P, Kaplan-Lefko PJ, Berent-Maoz B, Ribas A. PMID: 30409823; PMCID: PMC6359988.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimalsCells
    31. Myeloid Disease Mutations of Splicing Factor SRSF2 Cause G2-M Arrest and Skewed Differentiation of Human Hematopoietic Stem and Progenitor Cells. Stem Cells. 2018 11; 36(11):1663-1675. Bapat A, Keita N, Martelly W, Kang P, Seet C, Jacobsen JR, Stoilov P, Hu C, Crooks GM, Sharma S. PMID: 30004607; PMCID: PMC6283046.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansCells
    32. Transcriptionally and Functionally Distinct Mesenchymal Subpopulations Are Generated from Human Pluripotent Stem Cells. Stem Cell Reports. 2018 02 13; 10(2):436-446. Chin CJ, Li S, Corselli M, Casero D, Zhu Y, He CB, Hardy R, Péault B, Crooks GM. PMID: 29307583; PMCID: PMC5830911.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansCells
    33. Generation of mature T cells from human hematopoietic stem and progenitor cells in artificial thymic organoids. Nat Methods. 2017 May; 14(5):521-530. Seet CS, He C, Bethune MT, Li S, Chick B, Gschweng EH, Zhu Y, Kim K, Kohn DB, Baltimore D, Crooks GM, Montel-Hagen A. PMID: 28369043; PMCID: PMC5426913.
      View in: PubMed   Mentions: 117     Fields:    Translation:HumansCells
    34. The T-ALL related gene BCL11B regulates the initial stages of human T-cell differentiation. Leukemia. 2017 11; 31(11):2503-2514. Ha VL, Luong A, Li F, Casero D, Malvar J, Kim YM, Bhatia R, Crooks GM, Parekh C. PMID: 28232744; PMCID: PMC5599326.
      View in: PubMed   Mentions: 31     Fields:    Translation:HumansCells
    35. Medial HOXA genes demarcate haematopoietic stem cell fate during human development. Nat Cell Biol. 2016 06; 18(6):595-606. Dou DR, Calvanese V, Sierra MI, Nguyen AT, Minasian A, Saarikoski P, Sasidharan R, Ramirez CM, Zack JA, Crooks GM, Galic Z, Mikkola HK. PMID: 27183470; PMCID: PMC4981340.
      View in: PubMed   Mentions: 62     Fields:    Translation:HumansCells
    36. Genetic Tagging During Human Mesoderm Differentiation Reveals Tripotent Lateral Plate Mesodermal Progenitors. Stem Cells. 2016 05; 34(5):1239-50. Chin CJ, Cooper AR, Lill GR, Evseenko D, Zhu Y, He CB, Casero D, Pellegrini M, Kohn DB, Crooks GM. PMID: 26934332; PMCID: PMC5052131.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansAnimalsCells
    37. BALR-6 regulates cell growth and cell survival in B-lymphoblastic leukemia. Mol Cancer. 2015 Dec 22; 14:214. Rodríguez-Malavé NI, Fernando TR, Patel PC, Contreras JR, Palanichamy JK, Tran TM, Anguiano J, Davoren MJ, Alberti MO, Pioli KT, Sandoval S, Crooks GM, Rao DS. PMID: 26694754; PMCID: PMC4688921.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansAnimalsCells
    38. Long non-coding RNA profiling of human lymphoid progenitor cells reveals transcriptional divergence of B cell and T cell lineages. Nat Immunol. 2015 Dec; 16(12):1282-91. Casero D, Sandoval S, Seet CS, Scholes J, Zhu Y, Ha VL, Luong A, Parekh C, Crooks GM. PMID: 26502406; PMCID: PMC4653072.
      View in: PubMed   Mentions: 111     Fields:    Translation:HumansCells
    39. Unrelated donor hematopoietic stem cell transplantation for the treatment of non-malignant genetic diseases: An alemtuzumab based regimen is associated with cure of clinical disease; earlier clearance of alemtuzumab may be associated with graft rejection. Am J Hematol. 2015 Nov; 90(11):1021-6. Abdel-Azim H, Mahadeo KM, Zhao Q, Khazal S, Kohn DB, Crooks GM, Shah AJ, Kapoor N. PMID: 26242764.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    40. The expansion of thymopoiesis in neonatal mice is dependent on expression of high mobility group a 2 protein (Hmga2). PLoS One. 2015; 10(5):e0125414. Berent-Maoz B, Montecino-Rodriguez E, Fice M, Casero D, Seet CS, Crooks GM, Lowry W, Dorshkind K. PMID: 25933067; PMCID: PMC4416735.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimalsCells
    41. Lysophosphatidic acid mediates fibrosis in injured joints by regulating collagen type I biosynthesis. Osteoarthritis Cartilage. 2015 Feb; 23(2):308-18. Wu L, Petrigliano FA, Ba K, Lee S, Bogdanov J, McAllister DR, Adams JS, Rosenthal AK, Van Handel B, Crooks GM, Lin Y, Evseenko D. PMID: 25464168; PMCID: PMC4465392.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansAnimals
    42. A reduced-toxicity regimen is associated with durable engraftment and clinical cure of nonmalignant genetic diseases among children undergoing blood and marrow transplantation with an HLA-matched related donor. Biol Blood Marrow Transplant. 2015 Mar; 21(3):440-4. Mahadeo KM, Weinberg KI, Abdel-Azim H, Miklos DB, Killen R, Kohn D, Crooks GM, Shah AJ, Kharbanda S, Agarwal R, Kapoor N. PMID: 25459642.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCTClinical Trials
    43. GPI-80 defines self-renewal ability in hematopoietic stem cells during human development. Cell Stem Cell. 2015 Jan 08; 16(1):80-7. Prashad SL, Calvanese V, Yao CY, Kaiser J, Wang Y, Sasidharan R, Crooks G, Magnusson M, Mikkola HK. PMID: 25465114; PMCID: PMC4520393.
      View in: PubMed   Mentions: 45     Fields:    Translation:HumansCells
    44. Engineering the human thymic microenvironment to support thymopoiesis in vivo. Stem Cells. 2014 Sep; 32(9):2386-96. Chung B, Montel-Hagen A, Ge S, Blumberg G, Kim K, Klein S, Zhu Y, Parekh C, Balamurugan A, Yang OO, Crooks GM. PMID: 24801626; PMCID: PMC4138233.
      View in: PubMed   Mentions: 24     Fields:    Translation:HumansAnimals
    45. Erythropoiesis from human embryonic stem cells through erythropoietin-independent AKT signaling. Stem Cells. 2014 Jun; 32(6):1503-14. Kim WS, Zhu Y, Deng Q, Chin CJ, He CB, Grieco AJ, Dravid GG, Parekh C, Hollis RP, Lane TF, Bouhassira EE, Kohn DB, Crooks GM. PMID: 24677652; PMCID: PMC4037366.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCells
    46. Human lymphoid development in the absence of common γ-chain receptor signaling. J Immunol. 2014 Jun 01; 192(11):5050-8. Kohn LA, Seet CS, Scholes J, Codrea F, Chan R, Zaidi-Merchant S, Zhu Y, De Oliveira S, Kapoor N, Shah A, Abdel-Azim H, Kohn DB, Crooks GM. PMID: 24771849; PMCID: PMC4052377.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansAnimalsCellsCTClinical Trials
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