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William Edward Lowry

Title(s)Professor, Molecular, Cell and Developmental Biology
SchoolCollege of Letters and Science
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    Other Positions
    Title(s)Professor, Medicine


    Collapse Research 
    Collapse research activities and funding
    Metabolic Control of Hair Follicle Stem Cell Homeostasis and Tumorigenesis
    NIH R01AR084245Apr 11, 2024 - Mar 31, 2029
    Role: Principal Investigator
    iPS-Glial Restricted Progenitors in White Matter Repair for Stroke
    NIH R01NS103788May 15, 2018 - Feb 29, 2024
    Role: Co-Principal Investigator
    Metabolic Control of Hair Follicle Stem Cell Homeostasis and Tumorigenesis
    NIH R01AR070245Mar 12, 2018 - Feb 29, 2024
    Role: Principal Investigator
    Identification and characterization of cancer cells of origin in the epidermis
    NIH R01AR057409Mar 1, 2010 - Dec 31, 2014
    Role: Principal Investigator
    Role of Wnt and Noggin in development and Cancer
    NIH F32AR050340Jul 1, 2003 - Jun 30, 2006
    Role: Principal Investigator

    Collapse Bibliographic 
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. New insights into Rett syndrome pathogenesis: defining the role of MEPC2 in DNA damage. Front Neurol. 2026; 17:1711771. Mansooralavi N, Lowry WE. PMID: 42199960; PMCID: PMC13199075.
      View in: PubMed   Mentions:
    2. A single-cell multiomic analysis identifies molecular and gene-regulatory mechanisms dysregulated in developing Down syndrome neocortex. Science. 2026 Apr 23; 392(6796):eaea1259. Vuong CK, Weber A, Seong P, Matoba N, Chen YJ, Peyer J, Younesi S, Salinda A, Gomez D, Rivas G, Morales A, Shafie B, Zhang P, Nichterwitz S, Qi L, Fernandez NT, Friedman E, Love MI, Gandal MJ, Geschwind DH, Lowry WE, Stein JL, de la Torre-Ubieta L. PMID: 42024758; PMCID: PMC13225313.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    3. Glutamine addiction is a therapeutic target to block emergency myelopoiesis. bioRxiv. 2026 Mar 30. Olson OC, Zhang R, Proven MA, Swann JC, Huang K, Lowry WE, Passegue E. PMID: 41959003; PMCID: PMC13060292.
      View in: PubMed   Mentions:
    4. Probing DNA damage in Rett syndrome neurons uncovers a role for MECP2 regulation of PARP1. Stem Cell Reports. 2025 Oct 14; 20(10):102645. Morales A, Korsakova E, Mansooralavi N, Ravikumar A, Rivas G, Soliman P, Rodriguez L, McDaniel T, Lund A, Cooper B, Bhaduri A, Lowry WE. PMID: 41005313; PMCID: PMC12790717.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    5. Evidence of neuronal DNA damage in the brains of patients with Rett syndrome. Dis Model Mech. 2025 Aug 01; 18(8). Morales A, Korsakova E, Mansooralavi N, Soliman P, Jahanbani S, Olsen ML, Badhuri A, Lowry WE. PMID: 40739790; PMCID: PMC12452059.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    6. Hangry hairs: intermittent fasting linked to hair loss. Cell Res. 2025 May; 35(5):330-331. Galvan C, Lowry WE. PMID: 40000774; PMCID: PMC12012101.
      View in: PubMed   Mentions:    Fields:    
    7. Inhibition of Pyruvate Oxidation Diminishes Melanoma Progression. J Invest Dermatol. 2025 May; 145(5):1237-1241.e2. Seyran B, Avila I, Galvan C, Robles G, Murphy C, Christofk HR, Lowry WE. PMID: 39566840.
      View in: PubMed   Mentions:    Fields:    
    8. Defining metabolic flexibility in hair follicle stem cell induced squamous cell carcinoma. Sci Adv. 2024 09 20; 10(38):eadn2806. Galvan C, Flores AA, Cerrilos V, Avila I, Murphy C, Zheng W, Christofk HR, Lowry WE. PMID: 39303037; PMCID: PMC11414736.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimalsCells
    9. Yo-yoing stem cells defy dogma to maintain hair colour. Nature. 2023 04; 616(7958):666-667. Galvan C, Lowry WE. PMID: 37076710.
      View in: PubMed   Mentions:    Fields:    Translation:Cells
    10. Molecular signatures underlying neurofibrillary tangle susceptibility in Alzheimer's disease. Neuron. 2022 09 21; 110(18):2929-2948.e8. Otero-Garcia M, Mahajani SU, Wakhloo D, Tang W, Xue YQ, Morabito S, Pan J, Oberhauser J, Madira AE, Shakouri T, Deng Y, Allison T, He Z, Lowry WE, Kawaguchi R, Swarup V, Cobos I. PMID: 35882228; PMCID: PMC9509477.
      View in: PubMed   Mentions: 121     Fields:    Translation:HumansCells
    11. Single-nucleus transcriptome analysis reveals disease- and regeneration-associated endothelial cells in white matter vascular dementia. J Cell Mol Med. 2022 06; 26(11):3183-3195. Mitroi DN, Tian M, Kawaguchi R, Lowry WE, Carmichael ST. PMID: 35543222; PMCID: PMC9170821.
      View in: PubMed   Mentions: 21     Fields:    Translation:HumansCells
    12. Defining the nature of human pluripotent stem cell-derived interneurons via single-cell analysis. Stem Cell Reports. 2021 10 12; 16(10):2548-2564. Allison T, Langerman J, Sabri S, Otero-Garcia M, Lund A, Huang J, Wei X, Samarasinghe RA, Polioudakis D, Mody I, Cobos I, Novitch BG, Geschwind DH, Plath K, Lowry WE. PMID: 34506726; PMCID: PMC8514853.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansCells
    13. K Locus Effects in Gray Wolves: Experimental Assessment of TLR3 Signaling and the Gene Expression Response to Canine Distemper Virus. J Hered. 2021 08 25; 112(5):458-468. Johnston RA, Rheinwald JG, vonHoldt BM, Stahler DR, Lowry W, Tung J, Wayne RK. PMID: 34132805; PMCID: PMC8567826.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    14. Identification of neural oscillations and epileptiform changes in human brain organoids. Nat Neurosci. 2021 10; 24(10):1488-1500. Samarasinghe RA, Miranda OA, Buth JE, Mitchell S, Ferando I, Watanabe M, Allison TF, Kurdian A, Fotion NN, Gandal MJ, Golshani P, Plath K, Lowry WE, Parent JM, Mody I, Novitch BG. PMID: 34426698; PMCID: PMC9070733.
      View in: PubMed   Mentions: 153     Fields:    Translation:HumansCells
    15. Defining a Role for G-Protein Coupled Receptor/cAMP/CRE-Binding Protein Signaling in Hair Follicle Stem Cell Activation. J Invest Dermatol. 2022 01; 142(1):53-64.e3. Miranda M, Avila I, Esparza J, Shwartz Y, Hsu YC, Berdeaux R, Lowry WE. PMID: 34280464; PMCID: PMC8989631.
      View in: PubMed   Mentions: 8     Fields:    Translation:AnimalsCells
    16. Reliable generation of glial enriched progenitors from human fibroblast-derived iPSCs. Stem Cell Res. 2021 08; 55:102458. Llorente IL, Hatanaka EA, Meadow ME, Xie Y, Lowry WE, Carmichael ST. PMID: 34274773; PMCID: PMC8444576.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimalsCells
    17. Patient-derived glial enriched progenitors repair functional deficits due to white matter stroke and vascular dementia in rodents. Sci Transl Med. 2021 04 21; 13(590). Llorente IL, Xie Y, Mazzitelli JA, Hatanaka EA, Cinkornpumin J, Miller DR, Lin Y, Lowry WE, Carmichael ST. PMID: 33883275.
      View in: PubMed   Mentions: 32     Fields:    Translation:HumansAnimalsCells
    18. Inhibition of pyruvate oxidation as a versatile stimulator of the hair cycle in models of alopecia. Exp Dermatol. 2021 04; 30(4):448-456. Flores A, Choi S, Hsu YC, Lowry WE. PMID: 33739490.
      View in: PubMed   Mentions: 4     Fields:    Translation:AnimalsCells
    19. Development of Novel Mitochondrial Pyruvate Carrier Inhibitors to Treat Hair Loss. J Med Chem. 2021 02 25; 64(4):2046-2063. Liu X, Flores AA, Situ L, Gu W, Ding H, Christofk HR, Lowry WE, Jung ME. PMID: 33534563; PMCID: PMC8939290.
      View in: PubMed   Mentions: 15     Fields:    Translation:AnimalsCells
    20. Differential Gene Set Enrichment Analysis: a statistical approach to quantify the relative enrichment of two gene sets. Bioinformatics. 2021 01 29; 36(21):5247-5254. Joly JH, Lowry WE, Graham NA. PMID: 32692836; PMCID: PMC8453775.
      View in: PubMed   Mentions: 22     Fields:    Translation:HumansCells
    21. Its written all over your face: The molecular and physiological consequences of aging skin. Mech Ageing Dev. 2020 09; 190:111315. Lowry WE. PMID: 32681843; PMCID: PMC8911920.
      View in: PubMed   Mentions: 13     Fields:    Translation:Humans
    22. Defining Transcriptional Signatures of Human Hair Follicle Cell States. J Invest Dermatol. 2020 04; 140(4):764-773.e4. Takahashi R, Grzenda A, Allison TF, Rawnsley J, Balin SJ, Sabri S, Plath K, Lowry WE. PMID: 31676413; PMCID: PMC7093259.
      View in: PubMed   Mentions: 49     Fields:    Translation:HumansAnimalsCells
    23. A Single-Cell Transcriptomic Atlas of Human Neocortical Development during Mid-gestation. Neuron. 2019 09 04; 103(5):785-801.e8. Polioudakis D, de la Torre-Ubieta L, Langerman J, Elkins AG, Shi X, Stein JL, Vuong CK, Nichterwitz S, Gevorgian M, Opland CK, Lu D, Connell W, Ruzzo EK, Lowe JK, Hadzic T, Hinz FI, Sabri S, Lowry WE, Gerstein MB, Plath K, Geschwind DH. PMID: 31303374; PMCID: PMC6831089.
      View in: PubMed   Mentions: 281     Fields:    Translation:HumansCells
    24. Author Correction: Increased lactate dehydrogenase activity is dispensable in squamous carcinoma cells of origin. Nat Commun. 2019 03 26; 10(1):1449. Flores A, Sandoval-Gonzalez S, Takahashi R, Krall A, Sathe L, Wei L, Radu C, Joly JH, Graham NA, Christofk HR, Lowry WE. PMID: 30914644; PMCID: PMC6435690.
      View in: PubMed   Mentions:    Fields:    
    25. Correction to: Differentiation of RPE cells from integration-free iPS cells and their cell biological characterization. Stem Cell Res Ther. 2019 Feb 12; 10(1):52. Hazim RA, Karumbayaram S, Jiang M, Dimashkie A, Lopes VS, Li D, Burgess BL, Vijayaraj P, Alva-Ornelas JA, Zack JA, Kohn DB, Gomperts BN, Pyle AD, Lowry WE, Williams DS. PMID: 30755264; PMCID: PMC6373121.
      View in: PubMed   Mentions: 1     Fields:    
    26. Increased lactate dehydrogenase activity is dispensable in squamous carcinoma cells of origin. Nat Commun. 2019 01 09; 10(1):91. Flores A, Sandoval-Gonzalez S, Takahashi R, Krall A, Sathe L, Wei L, Radu C, Joly JH, Graham NA, Christofk HR, Lowry WE. PMID: 30626875; PMCID: PMC6327029.
      View in: PubMed   Mentions: 23     Fields:    Translation:Animals
    27. The WNT10B Network Is Associated with Survival and Metastases in Chemoresistant Triple-Negative Breast Cancer. Cancer Res. 2019 03 01; 79(5):982-993. El Ayachi I, Fatima I, Wend P, Alva-Ornelas JA, Runke S, Kuenzinger WL, Silva J, Silva W, Gray JK, Lehr S, Barch HC, Krutilina RI, White AC, Cardiff R, Yee LD, Yang L, O'Regan RM, Lowry WE, Seagroves TN, Seewaldt V, Krum SA, Miranda-Carboni GA. PMID: 30563890; PMCID: PMC6855600.
      View in: PubMed   Mentions: 49     Fields:    Translation:HumansAnimalsCells
    28. Extracellular Matrix Remodeling Regulates Glucose Metabolism through TXNIP Destabilization. Cell. 2018 09 20; 175(1):117-132.e21. Sullivan WJ, Mullen PJ, Schmid EW, Flores A, Momcilovic M, Sharpley MS, Jelinek D, Whiteley AE, Maxwell MB, Wilde BR, Banerjee U, Coller HA, Shackelford DB, Braas D, Ayer DE, de Aguiar Vallim TQ, Lowry WE, Christofk HR. PMID: 30197082; PMCID: PMC6151140.
      View in: PubMed   Mentions: 152     Fields:    Translation:HumansCells
    29. Apparent bias toward long gene misregulation in MeCP2 syndromes disappears after controlling for baseline variations. Nat Commun. 2018 08 13; 9(1):3225. Raman AT, Pohodich AE, Wan YW, Yalamanchili HK, Lowry WE, Zoghbi HY, Liu Z. PMID: 30104565; PMCID: PMC6089998.
      View in: PubMed   Mentions: 29     Fields:    Translation:HumansAnimalsCells
    30. Hip to the Game: YAP/TAZ is required for nonmelanoma skin cancers. EMBO J. 2018 09 03; 37(17). Miranda MM, Lowry WE. PMID: 30037822; PMCID: PMC6120656.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCells
    31. Mapping Metabolism: Monitoring Lactate Dehydrogenase Activity Directly in Tissue. J Vis Exp. 2018 06 21; (136). Jelinek D, Flores A, Uebelhoer M, Pasque V, Plath K, Iruela-Arispe ML, Christofk HR, Lowry WE, Coller HA. PMID: 29985359; PMCID: PMC6101961.
      View in: PubMed   Mentions: 6     Fields:    Translation:Animals
    32. Loss of MECP2 Leads to Activation of P53 and Neuronal Senescence. Stem Cell Reports. 2018 05 08; 10(5):1453-1463. Ohashi M, Korsakova E, Allen D, Lee P, Fu K, Vargas BS, Cinkornpumin J, Salas C, Park JC, Germanguz I, Langerman J, Chronis C, Kuoy E, Tran S, Xiao X, Pellegrini M, Plath K, Lowry WE. PMID: 29742391; PMCID: PMC5995366.
      View in: PubMed   Mentions: 49     Fields:    Translation:HumansCells
    33. Publisher Correction: Stem cells: The reprogramming method matters. Nat Biomed Eng. 2018 01; 2(1):50. Allison TF, Lowry WE. PMID: 31015656.
      View in: PubMed   Mentions:    Fields:    
    34. A small molecule screen to identify regulators of let-7 targets. Sci Rep. 2017 11 21; 7(1):15973. Cinkornpumin J, Roos M, Nguyen L, Liu X, Gaeta X, Lin S, Chan DN, Liu A, Gregory RI, Jung M, Chute J, Zhu H, Lowry WE. PMID: 29162914; PMCID: PMC5698460.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansCells
    35. Topical Inhibition of the Electron Transport Chain Can Stimulate the Hair Cycle. J Invest Dermatol. 2018 04; 138(4):968-972. Miranda M, Christofk H, Jones DL, Lowry WE. PMID: 29106930; PMCID: PMC8966693.
      View in: PubMed   Mentions: 6     Fields:    Translation:AnimalsCells
    36. Melanocyte Stem Cell Activation and Translocation Initiate Cutaneous Melanoma in Response to UV Exposure. Cell Stem Cell. 2017 Nov 02; 21(5):665-678.e6. Moon H, Donahue LR, Choi E, Scumpia PO, Lowry WE, Grenier JK, Zhu J, White AC. PMID: 29033353; PMCID: PMC9004284.
      View in: PubMed   Mentions: 69     Fields:    Translation:AnimalsCells
    37. Differentiation of RPE cells from integration-free iPS cells and their cell biological characterization. Stem Cell Res Ther. 2017 10 02; 8(1):217. Hazim RA, Karumbayaram S, Jiang M, Dimashkie A, Lopes VS, Li D, Burgess BL, Vijayaraj P, Alva-Ornelas JA, Zack JA, Kohn DB, Gomperts BN, Pyle AD, Lowry WE, Williams DS. PMID: 28969679; PMCID: PMC5625837.
      View in: PubMed   Mentions: 40     Fields:    Translation:HumansAnimalsCells
    38. The reprogramming method matters. Nat Biomed Eng. 2017 Oct; 1(10):779-781. Allison TF, Lowry WE. PMID: 31015592.
      View in: PubMed   Mentions: 2     Fields:    
    39. Manipulation of neural progenitor fate through the oxygen sensing pathway. Methods. 2018 01 15; 133:44-53. Xie Y, Lowry WE. PMID: 28864353; PMCID: PMC5842432.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansCells
    40. Lactate dehydrogenase activity drives hair follicle stem cell activation. Nat Cell Biol. 2017 Sep; 19(9):1017-1026. Flores A, Schell J, Krall AS, Jelinek D, Miranda M, Grigorian M, Braas D, White AC, Zhou JL, Graham NA, Graeber T, Seth P, Evseenko D, Coller HA, Rutter J, Christofk HR, Lowry WE. PMID: 28812580; PMCID: PMC5657543.
      View in: PubMed   Mentions: 145     Fields:    Translation:AnimalsCells
    41. Control of intestinal stem cell function and proliferation by mitochondrial pyruvate metabolism. Nat Cell Biol. 2017 Sep; 19(9):1027-1036. Schell JC, Wisidagama DR, Bensard C, Zhao H, Wei P, Tanner J, Flores A, Mohlman J, Sorensen LK, Earl CS, Olson KA, Miao R, Waller TC, Delker D, Kanth P, Jiang L, DeBerardinis RJ, Bronner MP, Li DY, Cox JE, Christofk HR, Lowry WE, Thummel CS, Rutter J. PMID: 28812582; PMCID: PMC6137334.
      View in: PubMed   Mentions: 182     Fields:    Translation:HumansAnimalsCells
    42. Defining Transcriptional Regulatory Mechanisms for Primary let-7 miRNAs. PLoS One. 2017; 12(1):e0169237. Gaeta X, Le L, Lin Y, Xie Y, Lowry WE. PMID: 28052101; PMCID: PMC5215532.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimalsCells
    43. Human Embryonic Stem Cells Do Not Change Their X Inactivation Status during Differentiation. Cell Rep. 2017 01 03; 18(1):54-67. Patel S, Bonora G, Sahakyan A, Kim R, Chronis C, Langerman J, Fitz-Gibbon S, Rubbi L, Skelton RJP, Ardehali R, Pellegrini M, Lowry WE, Clark AT, Plath K. PMID: 27989715; PMCID: PMC5214931.
      View in: PubMed   Mentions: 59     Fields:    Translation:HumansCells
    44. Engineered HA hydrogel for stem cell transplantation in the brain: Biocompatibility data using a design of experiment approach. Data Brief. 2017 Feb; 10:202-209. Nih LR, Moshayedi P, Llorente IL, Berg AR, Cinkornpumin J, Lowry WE, Segura T, Carmichael ST. PMID: 27995155; PMCID: PMC5154973.
      View in: PubMed   Mentions: 18  
    45. RNA editing as an activator of self-renewal in cancer. Stem Cell Investig. 2016; 3:68. Germanguz I, Lowry WE. PMID: 27868050; PMCID: PMC5104573.
      View in: PubMed   Mentions: 1  
    46. Glycolytic Metabolism Plays a Functional Role in Regulating Human Pluripotent Stem Cell State. Cell Stem Cell. 2016 10 06; 19(4):476-490. Gu W, Gaeta X, Sahakyan A, Chan AB, Hong CS, Kim R, Braas D, Plath K, Lowry WE, Christofk HR. PMID: 27618217; PMCID: PMC5055460.
      View in: PubMed   Mentions: 166     Fields:    Translation:HumansAnimalsCells
    47. Systematic optimization of an engineered hydrogel allows for selective control of human neural stem cell survival and differentiation after transplantation in the stroke brain. Biomaterials. 2016 10; 105:145-155. Moshayedi P, Nih LR, Llorente IL, Berg AR, Cinkornpumin J, Lowry WE, Segura T, Carmichael ST. PMID: 27521617; PMCID: PMC5003628.
      View in: PubMed   Mentions: 106     Fields:    Translation:HumansAnimalsCells
    48. Tumor suppressor identity can contribute to heterogeneity of phenotype in hair follicle stem cell-induced squamous cell carcinoma. Exp Dermatol. 2016 09; 25(9):733-5. Flores A, Grant W, White AC, Scumpia P, Takahashi R, Lowry WE. PMID: 27095696; PMCID: PMC5002244.
      View in: PubMed   Mentions: 4     Fields:    Translation:Animals
    49. Exploiting Mouse Models to Study Ras-Induced Cutaneous Squamous Cell Carcinoma. J Invest Dermatol. 2016 08; 136(8):1543-1548. Lowry WE, Flores A, White AC. PMID: 27160068.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansAnimalsCells
    50. Hmga2 is dispensable for cutaneous squamous cell carcinoma. Exp Dermatol. 2016 05; 25(5):409-12. White A, Flores A, Ong J, Lowry WE. PMID: 26901496; PMCID: PMC4864169.
      View in: PubMed   Mentions: 6     Fields:    Translation:Animals
    51. Identifying gene expression modules that define human cell fates. Stem Cell Res. 2016 05; 16(3):712-24. Germanguz I, Listgarten J, Cinkornpumin J, Solomon A, Gaeta X, Lowry WE. PMID: 27108395; PMCID: PMC4903895.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    52. The expansion of thymopoiesis in neonatal mice is dependent on expression of high mobility group a 2 protein (Hmga2). PLoS One. 2015; 10(5):e0125414. Berent-Maoz B, Montecino-Rodriguez E, Fice M, Casero D, Seet CS, Crooks GM, Lowry W, Dorshkind K. PMID: 25933067; PMCID: PMC4416735.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimalsCells
    53. Delivery of iPS-NPCs to the Stroke Cavity within a Hyaluronic Acid Matrix Promotes the Differentiation of Transplanted Cells. Adv Funct Mater. 2014 Nov 26; 24(44):7053-7062. Lam J, Lowry WE, Carmichael ST, Segura T. PMID: 26213530; PMCID: PMC4512237.
      View in: PubMed   Mentions: 78  
    54. Hydrogel design of experiments methodology to optimize hydrogel for iPSC-NPC culture. Adv Healthc Mater. 2015 Mar 11; 4(4):534-9. Lam J, Carmichael ST, Lowry WE, Segura T. PMID: 25378176; PMCID: PMC4384641.
      View in: PubMed   Mentions: 64     Fields:    Translation:HumansCells
    55. Defining the role of oxygen tension in human neural progenitor fate. Stem Cell Reports. 2014 Nov 11; 3(5):743-57. Xie Y, Zhang J, Lin Y, Gaeta X, Meng X, Wisidagama DR, Cinkornpumin J, Koehler CM, Malone CS, Teitell MA, Lowry WE. PMID: 25418722; PMCID: PMC4235163.
      View in: PubMed   Mentions: 32     Fields:    Translation:HumansCells
    56. let-7 miRNAs can act through notch to regulate human gliogenesis. Stem Cell Reports. 2014 Nov 11; 3(5):758-73. Patterson M, Gaeta X, Loo K, Edwards M, Smale S, Cinkornpumin J, Xie Y, Listgarten J, Azghadi S, Douglass SM, Pellegrini M, Lowry WE. PMID: 25316189; PMCID: PMC4235151.
      View in: PubMed   Mentions: 55     Fields:    Translation:HumansCells
    57. Refining the role for adult stem cells as cancer cells of origin. Trends Cell Biol. 2015 Jan; 25(1):11-20. White AC, Lowry WE. PMID: 25242116; PMCID: PMC4275355.
      View in: PubMed   Mentions: 75     Fields:    Translation:HumansCells
    58. Stem cell quiescence acts as a tumour suppressor in squamous tumours. Nat Cell Biol. 2014 Jan; 16(1):99-107. White AC, Khuu JK, Dang CY, Hu J, Tran KV, Liu A, Gomez S, Zhang Z, Yi R, Scumpia P, Grigorian M, Lowry WE. PMID: 24335650; PMCID: PMC3874399.
      View in: PubMed   Mentions: 54     Fields:    Translation:HumansAnimalsCells
    59. Generation and characterization of transgene-free human induced pluripotent stem cells and conversion to putative clinical-grade status. Stem Cell Res Ther. 2013 Jul 26; 4(4):87. Awe JP, Lee PC, Ramathal C, Vega-Crespo A, Durruthy-Durruthy J, Cooper A, Karumbayaram S, Lowry WE, Clark AT, Zack JA, Sebastiano V, Kohn DB, Pyle AD, Martin MG, Lipshutz GS, Phelps PE, Pera RA, Byrne JA. PMID: 23890092; PMCID: PMC3854769.
      View in: PubMed   Mentions: 28     Fields:    Translation:HumansAnimalsCells
    60. -Oh no! hiPSCs misplace their 5hmCs. Cell Stem Cell. 2013 Jul 03; 13(1):10-1. Lowry WE. PMID: 23827705; PMCID: PMC3753777.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    61. The histone demethylase Jmjd3 sequentially associates with the transcription factors Tbx3 and Eomes to drive endoderm differentiation. EMBO J. 2013 May 15; 32(10):1393-408. Kartikasari AE, Zhou JX, Kanji MS, Chan DN, Sinha A, Grapin-Botton A, Magnuson MA, Lowry WE, Bhushan A. PMID: 23584530; PMCID: PMC3655467.
      View in: PubMed   Mentions: 58     Fields:    Translation:HumansAnimalsCells
    62. SMRT compounds abrogate cellular phenotypes of ataxia telangiectasia in neural derivatives of patient-specific hiPSCs. Nat Commun. 2013; 4:1824. Lee P, Martin NT, Nakamura K, Azghadi S, Amiri M, Ben-David U, Perlman S, Gatti RA, Hu H, Lowry WE. PMID: 23652012.
      View in: PubMed   Mentions: 21     Fields:    Translation:HumansCells
    63. PTK7 marks the first human developmental EMT in vitro. PLoS One. 2012; 7(11):e50432. Chan DN, Azghadi SF, Feng J, Lowry WE. PMID: 23209741; PMCID: PMC3508926.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCells
    64. Nipah virus envelope-pseudotyped lentiviruses efficiently target ephrinB2-positive stem cell populations in vitro and bypass the liver sink when administered in vivo. J Virol. 2013 Feb; 87(4):2094-108. Palomares K, Vigant F, Van Handel B, Pernet O, Chikere K, Hong P, Sherman SP, Patterson M, An DS, Lowry WE, Mikkola HK, Morizono K, Pyle AD, Lee B. PMID: 23192877; PMCID: PMC3571488.
      View in: PubMed   Mentions: 35     Fields:    Translation:HumansAnimalsCells
    65. Does transcription factor induced pluripotency accurately mimic embryo derived pluripotency? Curr Opin Genet Dev. 2012 Oct; 22(5):429-34. Lowry WE. PMID: 23079387; PMCID: PMC3753773.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimalsCells
    66. Dynamic distribution of linker histone H1.5 in cellular differentiation. PLoS Genet. 2012; 8(8):e1002879. Li JY, Patterson M, Mikkola HK, Lowry WE, Kurdistani SK. PMID: 22956909; PMCID: PMC3431313.
      View in: PubMed   Mentions: 48     Fields:    Translation:HumansCells
    67. From skin biopsy to neurons through a pluripotent intermediate under Good Manufacturing Practice protocols. Stem Cells Transl Med. 2012 Jan; 1(1):36-43. Karumbayaram S, Lee P, Azghadi SF, Cooper AR, Patterson M, Kohn DB, Pyle A, Clark A, Byrne J, Zack JA, Plath K, Lowry WE. PMID: 23197638; PMCID: PMC3727693.
      View in: PubMed   Mentions: 31     Fields:    Translation:HumansAnimalsCells
    68. Exploiting the origins of Ras mediated squamous cell carcinoma to develop novel therapeutic interventions. Small GTPases. 2011 Nov 01; 2(6):318-321. White AC, Lowry WE. PMID: 22545230; PMCID: PMC3337161.
      View in: PubMed   Mentions: 2     Fields:    
    69. Physically associated synthetic hydrogels with long-term covalent stabilization for cell culture and stem cell transplantation. Adv Mater. 2011 Nov 16; 23(43):5098-103. Zhang J, Tokatlian T, Zhong J, Ng QK, Patterson M, Lowry WE, Carmichael ST, Segura T. PMID: 21997799; PMCID: PMC3242734.
      View in: PubMed   Mentions: 22     Fields:    Translation:HumansAnimalsCells
    70. Defining the nature of human pluripotent stem cell progeny. Cell Res. 2012 Jan; 22(1):178-93. Patterson M, Chan DN, Ha I, Case D, Cui Y, Van Handel B, Mikkola HK, Lowry WE. PMID: 21844894; PMCID: PMC3351932.
      View in: PubMed   Mentions: 84     Fields:    Translation:HumansCells
    71. E-cadherin, a new mixer in the Yamanaka cocktail. EMBO Rep. 2011 Jul 01; 12(7):613-4. Lowry WE. PMID: 21701504; PMCID: PMC3128958.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCells
    72. Defining the origins of Ras/p53-mediated squamous cell carcinoma. Proc Natl Acad Sci U S A. 2011 May 03; 108(18):7425-30. White AC, Tran K, Khuu J, Dang C, Cui Y, Binder SW, Lowry WE. PMID: 21502519; PMCID: PMC3088581.
      View in: PubMed   Mentions: 120     Fields:    Translation:AnimalsCells
    73. Progress in understanding reprogramming to the induced pluripotent state. Nat Rev Genet. 2011 Apr; 12(4):253-65. Plath K, Lowry WE. PMID: 21415849; PMCID: PMC3273493.
      View in: PubMed   Mentions: 152     Fields:    Translation:HumansAnimalsCells
    74. Identification and classification of chromosomal aberrations in human induced pluripotent stem cells. Cell Stem Cell. 2010 Oct 08; 7(4):521-31. Mayshar Y, Ben-David U, Lavon N, Biancotti JC, Yakir B, Clark AT, Plath K, Lowry WE, Benvenisty N. PMID: 20887957.
      View in: PubMed   Mentions: 385     Fields:    Translation:HumansCells
    75. Female human iPSCs retain an inactive X chromosome. Cell Stem Cell. 2010 Sep 03; 7(3):329-42. Tchieu J, Kuoy E, Chin MH, Trinh H, Patterson M, Sherman SP, Aimiuwu O, Lindgren A, Hakimian S, Zack JA, Clark AT, Pyle AD, Lowry WE, Plath K. PMID: 20727844; PMCID: PMC2935700.
      View in: PubMed   Mentions: 154     Fields:    Translation:HumansCells
    76. Molecular analyses of human induced pluripotent stem cells and embryonic stem cells. Cell Stem Cell. 2010 Aug 06; 7(2):263-9. Chin MH, Pellegrini M, Plath K, Lowry WE. PMID: 20682452; PMCID: PMC3276111.
      View in: PubMed   Mentions: 77     Fields:    Translation:HumansCells
    77. Roadblocks en route to the clinical application of induced pluripotent stem cells. J Cell Sci. 2010 Mar 01; 123(Pt 5):643-51. Lowry WE, Quan WL. PMID: 20164303; PMCID: PMC10851774.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansAnimalsCells
    78. Genetic studies on the functional relevance of the protein prenyltransferases in skin keratinocytes. Hum Mol Genet. 2010 Apr 15; 19(8):1603-17. Lee R, Chang SY, Trinh H, Tu Y, White AC, Davies BS, Bergo MO, Fong LG, Lowry WE, Young SG. PMID: 20106865; PMCID: PMC2846164.
      View in: PubMed   Mentions: 26     Fields:    Translation:AnimalsCells
    79. Induced pluripotent stem cells and embryonic stem cells are distinguished by gene expression signatures. Cell Stem Cell. 2009 Jul 02; 5(1):111-23. Chin MH, Mason MJ, Xie W, Volinia S, Singer M, Peterson C, Ambartsumyan G, Aimiuwu O, Richter L, Zhang J, Khvorostov I, Ott V, Grunstein M, Lavon N, Benvenisty N, Croce CM, Clark AT, Baxter T, Pyle AD, Teitell MA, Pelegrini M, Plath K, Lowry WE. PMID: 19570518; PMCID: PMC3448781.
      View in: PubMed   Mentions: 481     Fields:    Translation:HumansAnimalsCells
    80. Derivation of primordial germ cells from human embryonic and induced pluripotent stem cells is significantly improved by coculture with human fetal gonadal cells. Stem Cells. 2009 Apr; 27(4):783-95. Park TS, Galic Z, Conway AE, Lindgren A, van Handel BJ, Magnusson M, Richter L, Teitell MA, Mikkola HK, Lowry WE, Plath K, Clark AT. PMID: 19350678; PMCID: PMC4357362.
      View in: PubMed   Mentions: 103     Fields:    Translation:HumansCells
    81. Directed differentiation of human-induced pluripotent stem cells generates active motor neurons. Stem Cells. 2009 Apr; 27(4):806-11. Karumbayaram S, Novitch BG, Patterson M, Umbach JA, Richter L, Lindgren A, Conway AE, Clark AT, Goldman SA, Plath K, Wiedau-Pazos M, Kornblum HI, Lowry WE. PMID: 19350680; PMCID: PMC2895909.
      View in: PubMed   Mentions: 161     Fields:    Translation:HumansCells
    82. The many ways to make an iPS cell. Nat Biotechnol. 2008 Nov; 26(11):1246-8. Lowry WE, Plath K. PMID: 18997764.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansAnimalsCells
    83. Copy number variant analysis of human embryonic stem cells. Stem Cells. 2008 Jun; 26(6):1484-9. Wu H, Kim KJ, Mehta K, Paxia S, Sundstrom A, Anantharaman T, Kuraishy AI, Doan T, Ghosh J, Pyle AD, Clark A, Lowry W, Fan G, Baxter T, Mishra B, Sun Y, Teitell MA. PMID: 18369100; PMCID: PMC3901366.
      View in: PubMed   Mentions: 25     Fields:    Translation:HumansCells
    84. Generation of human induced pluripotent stem cells from dermal fibroblasts. Proc Natl Acad Sci U S A. 2008 Feb 26; 105(8):2883-8. Lowry WE, Richter L, Yachechko R, Pyle AD, Tchieu J, Sridharan R, Clark AT, Plath K. PMID: 18287077; PMCID: PMC2268554.
      View in: PubMed   Mentions: 448     Fields:    Translation:HumansCells
    85. Signaling in adult stem cells. Front Biosci. 2007 May 01; 12:3911-27. Lowry WE, Richter L. PMID: 17485347.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansCells
    86. Canonical notch signaling functions as a commitment switch in the epidermal lineage. Genes Dev. 2006 Nov 01; 20(21):3022-35. Blanpain C, Lowry WE, Pasolli HA, Fuchs E. PMID: 17079689; PMCID: PMC1620020.
      View in: PubMed   Mentions: 255     Fields:    Translation:AnimalsCells
    87. Defining the impact of beta-catenin/Tcf transactivation on epithelial stem cells. Genes Dev. 2005 Jul 01; 19(13):1596-611. Lowry WE, Blanpain C, Nowak JA, Guasch G, Lewis L, Fuchs E. PMID: 15961525; PMCID: PMC1172065.
      View in: PubMed   Mentions: 183     Fields:    Translation:AnimalsCells
    88. Self-renewal, multipotency, and the existence of two cell populations within an epithelial stem cell niche. Cell. 2004 Sep 03; 118(5):635-48. Blanpain C, Lowry WE, Geoghegan A, Polak L, Fuchs E. PMID: 15339667.
      View in: PubMed   Mentions: 622     Fields:    Translation:AnimalsCells
    89. Defining the epithelial stem cell niche in skin. Science. 2004 Jan 16; 303(5656):359-63. Tumbar T, Guasch G, Greco V, Blanpain C, Lowry WE, Rendl M, Fuchs E. PMID: 14671312; PMCID: PMC2405920.
      View in: PubMed   Mentions: 923     Fields:    Translation:AnimalsCells
    90. Csk, a critical link of g protein signals to actin cytoskeletal reorganization. Dev Cell. 2002 Jun; 2(6):733-44. Lowry WE, Huang J, Ma YC, Ali S, Wang D, Williams DM, Okada M, Cole PA, Huang XY. PMID: 12062086.
      View in: PubMed   Mentions: 35     Fields:    Translation:HumansAnimalsCells
    91. Direct stimulation of Bruton's tyrosine kinase by G protein alpha subunits. Methods Enzymol. 2002; 345:464-9. Lowry WE, Ma YC, Cvejic S, Huang XY. PMID: 11665629.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    92. G Protein beta gamma subunits act on the catalytic domain to stimulate Bruton's agammaglobulinemia tyrosine kinase. J Biol Chem. 2002 Jan 11; 277(2):1488-92. Lowry WE, Huang XY. PMID: 11698416.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansAnimalsCells
    93. Interfascicular neurolysis in the severe carpal tunnel syndrome. A prospective, randomized, double-blind, controlled study. Clin Orthop Relat Res. 1988 Feb; 227:251-4. Lowry WE, Follender AB. PMID: 3276422.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansCTClinical Trials
    94. Traumatic avascular necrosis of the capitate bone-case report. J Hand Surg Am. 1981 May; 6(3):245-8. Lowry WE, Cord SA. PMID: 7240679.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
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