William Edward Lowry

Title(s)Professor, Molecular, Cell and Developmental Biology
SchoolCollege of Letters and Science
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    Other Positions
    Title(s)Professor, Medicine


    Collapse Research 
    Collapse Research Activities and Funding
    iPS-Glial Restricted Progenitors in White Matter Repair for Stroke
    NIH R01NS103788May 15, 2018 - Feb 28, 2023
    Role: Co-Principal Investigator
    Metabolic Control of Hair Follicle Stem Cell Homeostasis and Tumorigenesis
    NIH R01AR070245Mar 12, 2018 - Feb 28, 2023
    Role: Principal Investigator
    Identification and characterization of cancer cells of origin in the epidermis
    NIH R01AR057409Mar 1, 2010 - Dec 31, 2014
    Role: Principal Investigator
    Role of Wnt and Noggin in development and Cancer
    NIH F32AR050340Jul 1, 2003 - Jun 30, 2006
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Defining metabolic flexibility in hair follicle stem cell induced squamous cell carcinoma. Sci Adv. 2024 Sep 20; 10(38):eadn2806. Galvan C, Flores AA, Cerrilos V, Avila I, Murphy C, Zheng W, Christofk HR, Lowry WE. PMID: 39303037; PMCID: PMC11414736.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    2. Yo-yoing stem cells defy dogma to maintain hair colour. Nature. 2023 04; 616(7958):666-667. Galvan C, Lowry WE. PMID: 37076710.
      View in: PubMed   Mentions:    Fields:    Translation:Cells
    3. Molecular signatures underlying neurofibrillary tangle susceptibility in Alzheimer's disease. Neuron. 2022 09 21; 110(18):2929-2948.e8. Otero-Garcia M, Mahajani SU, Wakhloo D, Tang W, Xue YQ, Morabito S, Pan J, Oberhauser J, Madira AE, Shakouri T, Deng Y, Allison T, He Z, Lowry WE, Kawaguchi R, Swarup V, Cobos I. PMID: 35882228; PMCID: PMC9509477.
      View in: PubMed   Mentions: 45     Fields:    Translation:HumansCells
    4. Single-nucleus transcriptome analysis reveals disease- and regeneration-associated endothelial cells in white matter vascular dementia. J Cell Mol Med. 2022 06; 26(11):3183-3195. Mitroi DN, Tian M, Kawaguchi R, Lowry WE, Carmichael ST. PMID: 35543222; PMCID: PMC9170821.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansCells
    5. Defining the nature of human pluripotent stem cell-derived interneurons via single-cell analysis. Stem Cell Reports. 2021 10 12; 16(10):2548-2564. Allison T, Langerman J, Sabri S, Otero-Garcia M, Lund A, Huang J, Wei X, Samarasinghe RA, Polioudakis D, Mody I, Cobos I, Novitch BG, Geschwind DH, Plath K, Lowry WE. PMID: 34506726; PMCID: PMC8514853.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCells
    6. K Locus Effects in Gray Wolves: Experimental Assessment of TLR3 Signaling and the Gene Expression Response to Canine Distemper Virus. J Hered. 2021 08 25; 112(5):458-468. Johnston RA, Rheinwald JG, vonHoldt BM, Stahler DR, Lowry W, Tung J, Wayne RK. PMID: 34132805; PMCID: PMC8567826.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    7. Identification of neural oscillations and epileptiform changes in human brain organoids. Nat Neurosci. 2021 10; 24(10):1488-1500. Samarasinghe RA, Miranda OA, Buth JE, Mitchell S, Ferando I, Watanabe M, Allison TF, Kurdian A, Fotion NN, Gandal MJ, Golshani P, Plath K, Lowry WE, Parent JM, Mody I, Novitch BG. PMID: 34426698; PMCID: PMC9070733.
      View in: PubMed   Mentions: 95     Fields:    Translation:HumansCells
    8. Defining a Role for G-Protein Coupled Receptor/cAMP/CRE-Binding Protein Signaling in Hair Follicle Stem Cell Activation. J Invest Dermatol. 2022 01; 142(1):53-64.e3. Miranda M, Avila I, Esparza J, Shwartz Y, Hsu YC, Berdeaux R, Lowry WE. PMID: 34280464; PMCID: PMC8989631.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    9. Reliable generation of glial enriched progenitors from human fibroblast-derived iPSCs. Stem Cell Res. 2021 08; 55:102458. Llorente IL, Hatanaka EA, Meadow ME, Xie Y, Lowry WE, Carmichael ST. PMID: 34274773; PMCID: PMC8444576.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimalsCells
    10. Patient-derived glial enriched progenitors repair functional deficits due to white matter stroke and vascular dementia in rodents. Sci Transl Med. 2021 04 21; 13(590). Llorente IL, Xie Y, Mazzitelli JA, Hatanaka EA, Cinkornpumin J, Miller DR, Lin Y, Lowry WE, Carmichael ST. PMID: 33883275.
      View in: PubMed   Mentions: 22     Fields:    Translation:HumansAnimalsCells
    11. Inhibition of pyruvate oxidation as a versatile stimulator of the hair cycle in models of alopecia. Exp Dermatol. 2021 04; 30(4):448-456. Flores A, Choi S, Hsu YC, Lowry WE. PMID: 33739490.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    12. Development of Novel Mitochondrial Pyruvate Carrier Inhibitors to Treat Hair Loss. J Med Chem. 2021 02 25; 64(4):2046-2063. Liu X, Flores AA, Situ L, Gu W, Ding H, Christofk HR, Lowry WE, Jung ME. PMID: 33534563; PMCID: PMC8939290.
      View in: PubMed   Mentions: 8     Fields:    Translation:AnimalsCells
    13. Differential Gene Set Enrichment Analysis: a statistical approach to quantify the relative enrichment of two gene sets. Bioinformatics. 2021 01 29; 36(21):5247-5254. Joly JH, Lowry WE, Graham NA. PMID: 32692836; PMCID: PMC8453775.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansCells
    14. Its written all over your face: The molecular and physiological consequences of aging skin. Mech Ageing Dev. 2020 09; 190:111315. Lowry WE. PMID: 32681843; PMCID: PMC8911920.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    15. Defining Transcriptional Signatures of Human Hair Follicle Cell States. J Invest Dermatol. 2020 04; 140(4):764-773.e4. Takahashi R, Grzenda A, Allison TF, Rawnsley J, Balin SJ, Sabri S, Plath K, Lowry WE. PMID: 31676413; PMCID: PMC7093259.
      View in: PubMed   Mentions: 33     Fields:    Translation:HumansAnimalsCells
    16. A Single-Cell Transcriptomic Atlas of Human Neocortical Development during Mid-gestation. Neuron. 2019 09 04; 103(5):785-801.e8. Polioudakis D, de la Torre-Ubieta L, Langerman J, Elkins AG, Shi X, Stein JL, Vuong CK, Nichterwitz S, Gevorgian M, Opland CK, Lu D, Connell W, Ruzzo EK, Lowe JK, Hadzic T, Hinz FI, Sabri S, Lowry WE, Gerstein MB, Plath K, Geschwind DH. PMID: 31303374; PMCID: PMC6831089.
      View in: PubMed   Mentions: 206     Fields:    Translation:HumansCells
    17. Author Correction: Increased lactate dehydrogenase activity is dispensable in squamous carcinoma cells of origin. Nat Commun. 2019 03 26; 10(1):1449. Flores A, Sandoval-Gonzalez S, Takahashi R, Krall A, Sathe L, Wei L, Radu C, Joly JH, Graham NA, Christofk HR, Lowry WE. PMID: 30914644; PMCID: PMC6435690.
      View in: PubMed   Mentions:    Fields:    
    18. Correction to: Differentiation of RPE cells from integration-free iPS cells and their cell biological characterization. Stem Cell Res Ther. 2019 Feb 12; 10(1):52. Hazim RA, Karumbayaram S, Jiang M, Dimashkie A, Lopes VS, Li D, Burgess BL, Vijayaraj P, Alva-Ornelas JA, Zack JA, Kohn DB, Gomperts BN, Pyle AD, Lowry WE, Williams DS. PMID: 30755264; PMCID: PMC6373121.
      View in: PubMed   Mentions:    Fields:    
    19. Increased lactate dehydrogenase activity is dispensable in squamous carcinoma cells of origin. Nat Commun. 2019 01 09; 10(1):91. Flores A, Sandoval-Gonzalez S, Takahashi R, Krall A, Sathe L, Wei L, Radu C, Joly JH, Graham NA, Christofk HR, Lowry WE. PMID: 30626875; PMCID: PMC6327029.
      View in: PubMed   Mentions: 21     Fields:    Translation:Animals
    20. The WNT10B Network Is Associated with Survival and Metastases in Chemoresistant Triple-Negative Breast Cancer. Cancer Res. 2019 03 01; 79(5):982-993. El Ayachi I, Fatima I, Wend P, Alva-Ornelas JA, Runke S, Kuenzinger WL, Silva J, Silva W, Gray JK, Lehr S, Barch HC, Krutilina RI, White AC, Cardiff R, Yee LD, Yang L, O'Regan RM, Lowry WE, Seagroves TN, Seewaldt V, Krum SA, Miranda-Carboni GA. PMID: 30563890; PMCID: PMC6855600.
      View in: PubMed   Mentions: 43     Fields:    Translation:HumansAnimalsCells
    21. Extracellular Matrix Remodeling Regulates Glucose Metabolism through TXNIP Destabilization. Cell. 2018 09 20; 175(1):117-132.e21. Sullivan WJ, Mullen PJ, Schmid EW, Flores A, Momcilovic M, Sharpley MS, Jelinek D, Whiteley AE, Maxwell MB, Wilde BR, Banerjee U, Coller HA, Shackelford DB, Braas D, Ayer DE, de Aguiar Vallim TQ, Lowry WE, Christofk HR. PMID: 30197082; PMCID: PMC6151140.
      View in: PubMed   Mentions: 120     Fields:    Translation:HumansCells
    22. Apparent bias toward long gene misregulation in MeCP2 syndromes disappears after controlling for baseline variations. Nat Commun. 2018 08 13; 9(1):3225. Raman AT, Pohodich AE, Wan YW, Yalamanchili HK, Lowry WE, Zoghbi HY, Liu Z. PMID: 30104565; PMCID: PMC6089998.
      View in: PubMed   Mentions: 21     Fields:    Translation:HumansAnimalsCells
    23. Hip to the Game: YAP/TAZ is required for nonmelanoma skin cancers. EMBO J. 2018 09 03; 37(17). Miranda MM, Lowry WE. PMID: 30037822; PMCID: PMC6120656.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCells
    24. Mapping Metabolism: Monitoring Lactate Dehydrogenase Activity Directly in Tissue. J Vis Exp. 2018 06 21; (136). Jelinek D, Flores A, Uebelhoer M, Pasque V, Plath K, Iruela-Arispe ML, Christofk HR, Lowry WE, Coller HA. PMID: 29985359; PMCID: PMC6101961.
      View in: PubMed   Mentions: 5     Fields:    Translation:Animals
    25. Loss of MECP2 Leads to Activation of P53 and Neuronal Senescence. Stem Cell Reports. 2018 05 08; 10(5):1453-1463. Ohashi M, Korsakova E, Allen D, Lee P, Fu K, Vargas BS, Cinkornpumin J, Salas C, Park JC, Germanguz I, Langerman J, Chronis C, Kuoy E, Tran S, Xiao X, Pellegrini M, Plath K, Lowry WE. PMID: 29742391; PMCID: PMC5995366.
      View in: PubMed   Mentions: 38     Fields:    Translation:HumansCells
    26. Publisher Correction: Stem cells: The reprogramming method matters. Nat Biomed Eng. 2018 01; 2(1):50. Allison TF, Lowry WE. PMID: 31015656.
      View in: PubMed   Mentions:    Fields:    
    27. A small molecule screen to identify regulators of let-7 targets. Sci Rep. 2017 11 21; 7(1):15973. Cinkornpumin J, Roos M, Nguyen L, Liu X, Gaeta X, Lin S, Chan DN, Liu A, Gregory RI, Jung M, Chute J, Zhu H, Lowry WE. PMID: 29162914; PMCID: PMC5698460.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansCells
    28. Topical Inhibition of the Electron Transport Chain Can Stimulate the Hair Cycle. J Invest Dermatol. 2018 04; 138(4):968-972. Miranda M, Christofk H, Jones DL, Lowry WE. PMID: 29106930; PMCID: PMC8966693.
      View in: PubMed   Mentions: 5     Fields:    Translation:AnimalsCells
    29. Melanocyte Stem Cell Activation and Translocation Initiate Cutaneous Melanoma in Response to UV Exposure. Cell Stem Cell. 2017 Nov 02; 21(5):665-678.e6. Moon H, Donahue LR, Choi E, Scumpia PO, Lowry WE, Grenier JK, Zhu J, White AC. PMID: 29033353; PMCID: PMC9004284.
      View in: PubMed   Mentions: 58     Fields:    Translation:AnimalsCells
    30. Differentiation of RPE cells from integration-free iPS cells and their cell biological characterization. Stem Cell Res Ther. 2017 10 02; 8(1):217. Hazim RA, Karumbayaram S, Jiang M, Dimashkie A, Lopes VS, Li D, Burgess BL, Vijayaraj P, Alva-Ornelas JA, Zack JA, Kohn DB, Gomperts BN, Pyle AD, Lowry WE, Williams DS. PMID: 28969679; PMCID: PMC5625837.
      View in: PubMed   Mentions: 34     Fields:    Translation:HumansAnimalsCells
    31. The reprogramming method matters. Nat Biomed Eng. 2017 Oct; 1(10):779-781. Allison TF, Lowry WE. PMID: 31015592.
      View in: PubMed   Mentions: 2     Fields:    
    32. Manipulation of neural progenitor fate through the oxygen sensing pathway. Methods. 2018 01 15; 133:44-53. Xie Y, Lowry WE. PMID: 28864353; PMCID: PMC5842432.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCells
    33. Lactate dehydrogenase activity drives hair follicle stem cell activation. Nat Cell Biol. 2017 Sep; 19(9):1017-1026. Flores A, Schell J, Krall AS, Jelinek D, Miranda M, Grigorian M, Braas D, White AC, Zhou JL, Graham NA, Graeber T, Seth P, Evseenko D, Coller HA, Rutter J, Christofk HR, Lowry WE. PMID: 28812580; PMCID: PMC5657543.
      View in: PubMed   Mentions: 120     Fields:    Translation:AnimalsCells
    34. Control of intestinal stem cell function and proliferation by mitochondrial pyruvate metabolism. Nat Cell Biol. 2017 Sep; 19(9):1027-1036. Schell JC, Wisidagama DR, Bensard C, Zhao H, Wei P, Tanner J, Flores A, Mohlman J, Sorensen LK, Earl CS, Olson KA, Miao R, Waller TC, Delker D, Kanth P, Jiang L, DeBerardinis RJ, Bronner MP, Li DY, Cox JE, Christofk HR, Lowry WE, Thummel CS, Rutter J. PMID: 28812582; PMCID: PMC6137334.
      View in: PubMed   Mentions: 146     Fields:    Translation:HumansAnimalsCells
    35. Defining Transcriptional Regulatory Mechanisms for Primary let-7 miRNAs. PLoS One. 2017; 12(1):e0169237. Gaeta X, Le L, Lin Y, Xie Y, Lowry WE. PMID: 28052101; PMCID: PMC5215532.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimalsCells
    36. Human Embryonic Stem Cells Do Not Change Their X Inactivation Status during Differentiation. Cell Rep. 2017 01 03; 18(1):54-67. Patel S, Bonora G, Sahakyan A, Kim R, Chronis C, Langerman J, Fitz-Gibbon S, Rubbi L, Skelton RJP, Ardehali R, Pellegrini M, Lowry WE, Clark AT, Plath K. PMID: 27989715; PMCID: PMC5214931.
      View in: PubMed   Mentions: 54     Fields:    Translation:HumansCells
    37. Engineered HA hydrogel for stem cell transplantation in the brain: Biocompatibility data using a design of experiment approach. Data Brief. 2017 Feb; 10:202-209. Nih LR, Moshayedi P, Llorente IL, Berg AR, Cinkornpumin J, Lowry WE, Segura T, Carmichael ST. PMID: 27995155; PMCID: PMC5154973.
      View in: PubMed   Mentions: 17  
    38. RNA editing as an activator of self-renewal in cancer. Stem Cell Investig. 2016; 3:68. Germanguz I, Lowry WE. PMID: 27868050; PMCID: PMC5104573.
      View in: PubMed   Mentions: 1  
    39. Glycolytic Metabolism Plays a Functional Role in Regulating Human Pluripotent Stem Cell State. Cell Stem Cell. 2016 10 06; 19(4):476-490. Gu W, Gaeta X, Sahakyan A, Chan AB, Hong CS, Kim R, Braas D, Plath K, Lowry WE, Christofk HR. PMID: 27618217; PMCID: PMC5055460.
      View in: PubMed   Mentions: 144     Fields:    Translation:HumansAnimalsCells
    40. Systematic optimization of an engineered hydrogel allows for selective control of human neural stem cell survival and differentiation after transplantation in the stroke brain. Biomaterials. 2016 10; 105:145-155. Moshayedi P, Nih LR, Llorente IL, Berg AR, Cinkornpumin J, Lowry WE, Segura T, Carmichael ST. PMID: 27521617; PMCID: PMC5003628.
      View in: PubMed   Mentions: 81     Fields:    Translation:HumansAnimalsCells
    41. Tumor suppressor identity can contribute to heterogeneity of phenotype in hair follicle stem cell-induced squamous cell carcinoma. Exp Dermatol. 2016 09; 25(9):733-5. Flores A, Grant W, White AC, Scumpia P, Takahashi R, Lowry WE. PMID: 27095696; PMCID: PMC5002244.
      View in: PubMed   Mentions: 4     Fields:    Translation:Animals
    42. Exploiting Mouse Models to Study Ras-Induced Cutaneous Squamous Cell Carcinoma. J Invest Dermatol. 2016 08; 136(8):1543-1548. Lowry WE, Flores A, White AC. PMID: 27160068.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansAnimalsCells
    43. Hmga2 is dispensable for cutaneous squamous cell carcinoma. Exp Dermatol. 2016 05; 25(5):409-12. White A, Flores A, Ong J, Lowry WE. PMID: 26901496; PMCID: PMC4864169.
      View in: PubMed   Mentions: 6     Fields:    Translation:Animals
    44. Identifying gene expression modules that define human cell fates. Stem Cell Res. 2016 05; 16(3):712-24. Germanguz I, Listgarten J, Cinkornpumin J, Solomon A, Gaeta X, Lowry WE. PMID: 27108395; PMCID: PMC4903895.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    45. The expansion of thymopoiesis in neonatal mice is dependent on expression of high mobility group a 2 protein (Hmga2). PLoS One. 2015; 10(5):e0125414. Berent-Maoz B, Montecino-Rodriguez E, Fice M, Casero D, Seet CS, Crooks GM, Lowry W, Dorshkind K. PMID: 25933067; PMCID: PMC4416735.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimalsCells
    46. Delivery of iPS-NPCs to the Stroke Cavity within a Hyaluronic Acid Matrix Promotes the Differentiation of Transplanted Cells. Adv Funct Mater. 2014 Nov 26; 24(44):7053-7062. Lam J, Lowry WE, Carmichael ST, Segura T. PMID: 26213530; PMCID: PMC4512237.
      View in: PubMed   Mentions: 65  
    47. Hydrogel design of experiments methodology to optimize hydrogel for iPSC-NPC culture. Adv Healthc Mater. 2015 Mar 11; 4(4):534-9. Lam J, Carmichael ST, Lowry WE, Segura T. PMID: 25378176; PMCID: PMC4384641.
      View in: PubMed   Mentions: 55     Fields:    Translation:HumansCells
    48. Defining the role of oxygen tension in human neural progenitor fate. Stem Cell Reports. 2014 Nov 11; 3(5):743-57. Xie Y, Zhang J, Lin Y, Gaeta X, Meng X, Wisidagama DR, Cinkornpumin J, Koehler CM, Malone CS, Teitell MA, Lowry WE. PMID: 25418722; PMCID: PMC4235163.
      View in: PubMed   Mentions: 29     Fields:    Translation:HumansCells
    49. let-7 miRNAs can act through notch to regulate human gliogenesis. Stem Cell Reports. 2014 Nov 11; 3(5):758-73. Patterson M, Gaeta X, Loo K, Edwards M, Smale S, Cinkornpumin J, Xie Y, Listgarten J, Azghadi S, Douglass SM, Pellegrini M, Lowry WE. PMID: 25316189; PMCID: PMC4235151.
      View in: PubMed   Mentions: 48     Fields:    Translation:HumansCells
    50. Refining the role for adult stem cells as cancer cells of origin. Trends Cell Biol. 2015 Jan; 25(1):11-20. White AC, Lowry WE. PMID: 25242116; PMCID: PMC4275355.
      View in: PubMed   Mentions: 68     Fields:    Translation:HumansCells
    51. Stem cell quiescence acts as a tumour suppressor in squamous tumours. Nat Cell Biol. 2014 Jan; 16(1):99-107. White AC, Khuu JK, Dang CY, Hu J, Tran KV, Liu A, Gomez S, Zhang Z, Yi R, Scumpia P, Grigorian M, Lowry WE. PMID: 24335650; PMCID: PMC3874399.
      View in: PubMed   Mentions: 52     Fields:    Translation:HumansAnimalsCells
    52. Generation and characterization of transgene-free human induced pluripotent stem cells and conversion to putative clinical-grade status. Stem Cell Res Ther. 2013 Jul 26; 4(4):87. Awe JP, Lee PC, Ramathal C, Vega-Crespo A, Durruthy-Durruthy J, Cooper A, Karumbayaram S, Lowry WE, Clark AT, Zack JA, Sebastiano V, Kohn DB, Pyle AD, Martin MG, Lipshutz GS, Phelps PE, Pera RA, Byrne JA. PMID: 23890092; PMCID: PMC3854769.
      View in: PubMed   Mentions: 26     Fields:    Translation:HumansAnimalsCells
    53. -Oh no! hiPSCs misplace their 5hmCs. Cell Stem Cell. 2013 Jul 03; 13(1):10-1. Lowry WE. PMID: 23827705; PMCID: PMC3753777.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    54. The histone demethylase Jmjd3 sequentially associates with the transcription factors Tbx3 and Eomes to drive endoderm differentiation. EMBO J. 2013 May 15; 32(10):1393-408. Kartikasari AE, Zhou JX, Kanji MS, Chan DN, Sinha A, Grapin-Botton A, Magnuson MA, Lowry WE, Bhushan A. PMID: 23584530; PMCID: PMC3655467.
      View in: PubMed   Mentions: 56     Fields:    Translation:HumansAnimalsCells
    55. SMRT compounds abrogate cellular phenotypes of ataxia telangiectasia in neural derivatives of patient-specific hiPSCs. Nat Commun. 2013; 4:1824. Lee P, Martin NT, Nakamura K, Azghadi S, Amiri M, Ben-David U, Perlman S, Gatti RA, Hu H, Lowry WE. PMID: 23652012.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansCells
    56. PTK7 marks the first human developmental EMT in vitro. PLoS One. 2012; 7(11):e50432. Chan DN, Azghadi SF, Feng J, Lowry WE. PMID: 23209741; PMCID: PMC3508926.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCells
    57. Nipah virus envelope-pseudotyped lentiviruses efficiently target ephrinB2-positive stem cell populations in vitro and bypass the liver sink when administered in vivo. J Virol. 2013 Feb; 87(4):2094-108. Palomares K, Vigant F, Van Handel B, Pernet O, Chikere K, Hong P, Sherman SP, Patterson M, An DS, Lowry WE, Mikkola HK, Morizono K, Pyle AD, Lee B. PMID: 23192877; PMCID: PMC3571488.
      View in: PubMed   Mentions: 24     Fields:    Translation:HumansAnimalsCells
    58. Does transcription factor induced pluripotency accurately mimic embryo derived pluripotency? Curr Opin Genet Dev. 2012 Oct; 22(5):429-34. Lowry WE. PMID: 23079387; PMCID: PMC3753773.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimalsCells
    59. Dynamic distribution of linker histone H1.5 in cellular differentiation. PLoS Genet. 2012; 8(8):e1002879. Li JY, Patterson M, Mikkola HK, Lowry WE, Kurdistani SK. PMID: 22956909; PMCID: PMC3431313.
      View in: PubMed   Mentions: 44     Fields:    Translation:HumansCells
    60. From skin biopsy to neurons through a pluripotent intermediate under Good Manufacturing Practice protocols. Stem Cells Transl Med. 2012 Jan; 1(1):36-43. Karumbayaram S, Lee P, Azghadi SF, Cooper AR, Patterson M, Kohn DB, Pyle A, Clark A, Byrne J, Zack JA, Plath K, Lowry WE. PMID: 23197638; PMCID: PMC3727693.
      View in: PubMed   Mentions: 30     Fields:    Translation:HumansAnimalsCells
    61. Exploiting the origins of Ras mediated squamous cell carcinoma to develop novel therapeutic interventions. Small GTPases. 2011 Nov 01; 2(6):318-321. White AC, Lowry WE. PMID: 22545230; PMCID: PMC3337161.
      View in: PubMed   Mentions: 2     Fields:    
    62. Physically associated synthetic hydrogels with long-term covalent stabilization for cell culture and stem cell transplantation. Adv Mater. 2011 Nov 16; 23(43):5098-103. Zhang J, Tokatlian T, Zhong J, Ng QK, Patterson M, Lowry WE, Carmichael ST, Segura T. PMID: 21997799; PMCID: PMC3242734.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansAnimalsCells
    63. Defining the nature of human pluripotent stem cell progeny. Cell Res. 2012 Jan; 22(1):178-93. Patterson M, Chan DN, Ha I, Case D, Cui Y, Van Handel B, Mikkola HK, Lowry WE. PMID: 21844894; PMCID: PMC3351932.
      View in: PubMed   Mentions: 78     Fields:    Translation:HumansCells
    64. E-cadherin, a new mixer in the Yamanaka cocktail. EMBO Rep. 2011 Jul 01; 12(7):613-4. Lowry WE. PMID: 21701504; PMCID: PMC3128958.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCells
    65. Defining the origins of Ras/p53-mediated squamous cell carcinoma. Proc Natl Acad Sci U S A. 2011 May 03; 108(18):7425-30. White AC, Tran K, Khuu J, Dang C, Cui Y, Binder SW, Lowry WE. PMID: 21502519; PMCID: PMC3088581.
      View in: PubMed   Mentions: 111     Fields:    Translation:AnimalsCells
    66. Progress in understanding reprogramming to the induced pluripotent state. Nat Rev Genet. 2011 Apr; 12(4):253-65. Plath K, Lowry WE. PMID: 21415849; PMCID: PMC3273493.
      View in: PubMed   Mentions: 144     Fields:    Translation:HumansAnimalsCells
    67. Identification and classification of chromosomal aberrations in human induced pluripotent stem cells. Cell Stem Cell. 2010 Oct 08; 7(4):521-31. Mayshar Y, Ben-David U, Lavon N, Biancotti JC, Yakir B, Clark AT, Plath K, Lowry WE, Benvenisty N. PMID: 20887957.
      View in: PubMed   Mentions: 374     Fields:    Translation:HumansCells
    68. Female human iPSCs retain an inactive X chromosome. Cell Stem Cell. 2010 Sep 03; 7(3):329-42. Tchieu J, Kuoy E, Chin MH, Trinh H, Patterson M, Sherman SP, Aimiuwu O, Lindgren A, Hakimian S, Zack JA, Clark AT, Pyle AD, Lowry WE, Plath K. PMID: 20727844; PMCID: PMC2935700.
      View in: PubMed   Mentions: 141     Fields:    Translation:HumansCells
    69. Molecular analyses of human induced pluripotent stem cells and embryonic stem cells. Cell Stem Cell. 2010 Aug 06; 7(2):263-9. Chin MH, Pellegrini M, Plath K, Lowry WE. PMID: 20682452; PMCID: PMC3276111.
      View in: PubMed   Mentions: 75     Fields:    Translation:HumansCells
    70. Roadblocks en route to the clinical application of induced pluripotent stem cells. J Cell Sci. 2010 Mar 01; 123(Pt 5):643-51. Lowry WE, Quan WL. PMID: 20164303; PMCID: PMC10851774.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansAnimalsCells
    71. Genetic studies on the functional relevance of the protein prenyltransferases in skin keratinocytes. Hum Mol Genet. 2010 Apr 15; 19(8):1603-17. Lee R, Chang SY, Trinh H, Tu Y, White AC, Davies BS, Bergo MO, Fong LG, Lowry WE, Young SG. PMID: 20106865; PMCID: PMC2846164.
      View in: PubMed   Mentions: 25     Fields:    Translation:AnimalsCells
    72. Induced pluripotent stem cells and embryonic stem cells are distinguished by gene expression signatures. Cell Stem Cell. 2009 Jul 02; 5(1):111-23. Chin MH, Mason MJ, Xie W, Volinia S, Singer M, Peterson C, Ambartsumyan G, Aimiuwu O, Richter L, Zhang J, Khvorostov I, Ott V, Grunstein M, Lavon N, Benvenisty N, Croce CM, Clark AT, Baxter T, Pyle AD, Teitell MA, Pelegrini M, Plath K, Lowry WE. PMID: 19570518; PMCID: PMC3448781.
      View in: PubMed   Mentions: 457     Fields:    Translation:HumansAnimalsCells
    73. Derivation of primordial germ cells from human embryonic and induced pluripotent stem cells is significantly improved by coculture with human fetal gonadal cells. Stem Cells. 2009 Apr; 27(4):783-95. Park TS, Galic Z, Conway AE, Lindgren A, van Handel BJ, Magnusson M, Richter L, Teitell MA, Mikkola HK, Lowry WE, Plath K, Clark AT. PMID: 19350678; PMCID: PMC4357362.
      View in: PubMed   Mentions: 98     Fields:    Translation:HumansCells
    74. Directed differentiation of human-induced pluripotent stem cells generates active motor neurons. Stem Cells. 2009 Apr; 27(4):806-11. Karumbayaram S, Novitch BG, Patterson M, Umbach JA, Richter L, Lindgren A, Conway AE, Clark AT, Goldman SA, Plath K, Wiedau-Pazos M, Kornblum HI, Lowry WE. PMID: 19350680; PMCID: PMC2895909.
      View in: PubMed   Mentions: 155     Fields:    Translation:HumansCells
    75. The many ways to make an iPS cell. Nat Biotechnol. 2008 Nov; 26(11):1246-8. Lowry WE, Plath K. PMID: 18997764.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansAnimalsCells
    76. Copy number variant analysis of human embryonic stem cells. Stem Cells. 2008 Jun; 26(6):1484-9. Wu H, Kim KJ, Mehta K, Paxia S, Sundstrom A, Anantharaman T, Kuraishy AI, Doan T, Ghosh J, Pyle AD, Clark A, Lowry W, Fan G, Baxter T, Mishra B, Sun Y, Teitell MA. PMID: 18369100; PMCID: PMC3901366.
      View in: PubMed   Mentions: 24     Fields:    Translation:HumansCells
    77. Generation of human induced pluripotent stem cells from dermal fibroblasts. Proc Natl Acad Sci U S A. 2008 Feb 26; 105(8):2883-8. Lowry WE, Richter L, Yachechko R, Pyle AD, Tchieu J, Sridharan R, Clark AT, Plath K. PMID: 18287077; PMCID: PMC2268554.
      View in: PubMed   Mentions: 430     Fields:    Translation:HumansCells
    78. Signaling in adult stem cells. Front Biosci. 2007 May 01; 12:3911-27. Lowry WE, Richter L. PMID: 17485347.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansCells
    79. Canonical notch signaling functions as a commitment switch in the epidermal lineage. Genes Dev. 2006 Nov 01; 20(21):3022-35. Blanpain C, Lowry WE, Pasolli HA, Fuchs E. PMID: 17079689; PMCID: PMC1620020.
      View in: PubMed   Mentions: 238     Fields:    Translation:AnimalsCells
    80. Defining the impact of beta-catenin/Tcf transactivation on epithelial stem cells. Genes Dev. 2005 Jul 01; 19(13):1596-611. Lowry WE, Blanpain C, Nowak JA, Guasch G, Lewis L, Fuchs E. PMID: 15961525; PMCID: PMC1172065.
      View in: PubMed   Mentions: 174     Fields:    Translation:AnimalsCells
    81. Self-renewal, multipotency, and the existence of two cell populations within an epithelial stem cell niche. Cell. 2004 Sep 03; 118(5):635-48. Blanpain C, Lowry WE, Geoghegan A, Polak L, Fuchs E. PMID: 15339667.
      View in: PubMed   Mentions: 582     Fields:    Translation:AnimalsCells
    82. Defining the epithelial stem cell niche in skin. Science. 2004 Jan 16; 303(5656):359-63. Tumbar T, Guasch G, Greco V, Blanpain C, Lowry WE, Rendl M, Fuchs E. PMID: 14671312; PMCID: PMC2405920.
      View in: PubMed   Mentions: 867     Fields:    Translation:AnimalsCells
    83. Csk, a critical link of g protein signals to actin cytoskeletal reorganization. Dev Cell. 2002 Jun; 2(6):733-44. Lowry WE, Huang J, Ma YC, Ali S, Wang D, Williams DM, Okada M, Cole PA, Huang XY. PMID: 12062086.
      View in: PubMed   Mentions: 33     Fields:    Translation:HumansAnimalsCells
    84. Direct stimulation of Bruton's tyrosine kinase by G protein alpha subunits. Methods Enzymol. 2002; 345:464-9. Lowry WE, Ma YC, Cvejic S, Huang XY. PMID: 11665629.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    85. G Protein beta gamma subunits act on the catalytic domain to stimulate Bruton's agammaglobulinemia tyrosine kinase. J Biol Chem. 2002 Jan 11; 277(2):1488-92. Lowry WE, Huang XY. PMID: 11698416.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansAnimalsCells
    86. Interfascicular neurolysis in the severe carpal tunnel syndrome. A prospective, randomized, double-blind, controlled study. Clin Orthop Relat Res. 1988 Feb; 227:251-4. Lowry WE, Follender AB. PMID: 3276422.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansCTClinical Trials
    87. Traumatic avascular necrosis of the capitate bone-case report. J Hand Surg Am. 1981 May; 6(3):245-8. Lowry WE, Cord SA. PMID: 7240679.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
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