Ranmal Aloka Samarasinghe

Title(s)Assistant Professor-in-Residence, Neurology
SchoolMedicine
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    Utilizing Human Brain Organoids to Model the Differential Effects of SCN8A Mutation on Cortex and Hippocampus
    NIH K08NS119747Jul 1, 2021 - Jun 30, 2026
    Role: Principal Investigator

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Human cerebellar organoids with functional Purkinje cells. Cell Stem Cell. 2024 01 04; 31(1):39-51.e6. Atamian A, Birtele M, Hosseini N, Nguyen T, Seth A, Del Dosso A, Paul S, Tedeschi N, Taylor R, Coba MP, Samarasinghe R, Lois C, Quadrato G. PMID: 38181749.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    2. Defining the nature of human pluripotent stem cell-derived interneurons via single-cell analysis. Stem Cell Reports. 2021 10 12; 16(10):2548-2564. Allison T, Langerman J, Sabri S, Otero-Garcia M, Lund A, Huang J, Wei X, Samarasinghe RA, Polioudakis D, Mody I, Cobos I, Novitch BG, Geschwind DH, Plath K, Lowry WE. PMID: 34506726; PMCID: PMC8514853.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCells
    3. Identification of neural oscillations and epileptiform changes in human brain organoids. Nat Neurosci. 2021 10; 24(10):1488-1500. Samarasinghe RA, Miranda OA, Buth JE, Mitchell S, Ferando I, Watanabe M, Allison TF, Kurdian A, Fotion NN, Gandal MJ, Golshani P, Plath K, Lowry WE, Parent JM, Mody I, Novitch BG. PMID: 34426698; PMCID: PMC9070733.
      View in: PubMed   Mentions: 79     Fields:    Translation:HumansCells
    4. Transient muscarinic and glutamatergic stimulation of neural stem cells triggers acute and persistent changes in differentiation. Neurobiol Dis. 2014 Oct; 70:252-61. Samarasinghe RA, Kanuparthi PS, Timothy Greenamyre J, DeFranco DB, Di Maio R. PMID: 25003306; PMCID: PMC4152385.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimalsCells
    5. Cooperativity and complementarity: synergies in non-classical and classical glucocorticoid signaling. Cell Cycle. 2012 Aug 01; 11(15):2819-27. Samarasinghe RA, Witchell SF, DeFranco DB. PMID: 22801547; PMCID: PMC3419059.
      View in: PubMed   Mentions: 33     Fields:    Translation:HumansCells
    6. Nongenomic glucocorticoid receptor action regulates gap junction intercellular communication and neural progenitor cell proliferation. Proc Natl Acad Sci U S A. 2011 Oct 04; 108(40):16657-62. Samarasinghe RA, Di Maio R, Volonte D, Galbiati F, Lewis M, Romero G, DeFranco DB. PMID: 21930911; PMCID: PMC3189065.
      View in: PubMed   Mentions: 63     Fields:    Translation:AnimalsCells
    7. The dopamine and cAMP regulated phosphoprotein, 32 kDa (DARPP-32) signaling pathway: a novel therapeutic target in traumatic brain injury. Exp Neurol. 2011 Jun; 229(2):300-7. Bales JW, Yan HQ, Ma X, Li Y, Samarasinghe R, Dixon CE. PMID: 21376040; PMCID: PMC3110667.
      View in: PubMed   Mentions: 17     Fields:    Translation:AnimalsCells
    8. The urgent need to increase support for the NIH's MD-PhD student fellowships. Acad Med. 2011 Mar; 86(3):277; author reply 277-8. Samarasinghe RA. PMID: 21346431.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    9. Selective inhibition of mitogen-activated protein kinase phosphatases by zinc accounts for extracellular signal-regulated kinase 1/2-dependent oxidative neuronal cell death. Mol Pharmacol. 2008 Oct; 74(4):1141-51. Ho Y, Samarasinghe R, Knoch ME, Lewis M, Aizenman E, DeFranco DB. PMID: 18635668; PMCID: PMC2575064.
      View in: PubMed   Mentions: 36     Fields:    Translation:AnimalsCells
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