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Genetic Screen in a Preclinical Model of Sarcoma Development Defines Drivers and Therapeutic Vulnerabilities. Clin Cancer Res. 2024 Nov 01; 30(21):4957-4973.
Freeland J, Muñoz M, O'Donnell E, Langerman J, Darrow M, Bergonio J, Suarez-Navarro J, Thorpe S, Canter R, Randall RL, Plath K, Carraway KL, Witte ON, Graeber TG, Carr-Ascher JR. PMID: 39177582; PMCID: PMC11530313.
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PubMed Mentions: Fields:
Translation:
HumansAnimalsCells
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A critical role for X-chromosome architecture in mammalian X-chromosome dosage compensation. Curr Opin Genet Dev. 2024 Aug; 87:102235.
Dror I, Tan T, Plath K. PMID: 39053028; PMCID: PMC11317216.
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PubMed Mentions: Fields:
Translation:
HumansAnimalsCells
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Loss of cell junctional components and matrix alterations drive cell desquamation and fibrotic changes in Idiopathic Pulmonary Fibrosis. bioRxiv. 2024 Jun 22.
Chandran RR, Vijayaraj P, Garcia-Milian R, King J, Castillo K, Chen L, Kwon Y, William S, Rickabaugh TM, Langerman J, Choi W, Sen C, Lever JEP, Li Q, Pavelkova N, Plosa EJ, Rowe SM, Plath K, Clair G, Gomperts BN. PMID: 38948715; PMCID: PMC11212876.
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PubMed Mentions:
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RNA: The Unsuspected Conductor in the Orchestra of Macromolecular Crowding. Chem Rev. 2024 Apr 24; 124(8):4734-4777.
Zacco E, Broglia L, Kurihara M, Monti M, Gustincich S, Pastore A, Plath K, Nagakawa S, Cerase A, Sanchez de Groot N, Tartaglia GG. PMID: 38579177; PMCID: PMC11046439.
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PubMed Mentions:
1 Fields:
Translation:
HumansAnimalsCells
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Optimization of RNA Pepper Sensors for the Detection of Arbitrary RNA Targets. ACS Synth Biol. 2024 02 16; 13(2):498-508.
Tang AA, Afasizheva A, Cano CT, Plath K, Black D, Franco E. PMID: 38295291.
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PubMed Mentions: Fields:
Translation:
Cells
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XIST directly regulates X-linked and autosomal genes in naive human pluripotent cells. Cell. 2024 01 04; 187(1):110-129.e31.
Dror I, Chitiashvili T, Tan SYX, Cano CT, Sahakyan A, Markaki Y, Chronis C, Collier AJ, Deng W, Liang G, Sun Y, Afasizheva A, Miller J, Xiao W, Black DL, Ding F, Plath K. PMID: 38181737; PMCID: PMC10783549.
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PubMed Mentions:
8 Fields:
Translation:
HumansAnimalsCells
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Associating growth factor secretions and transcriptomes of single cells in nanovials using SEC-seq. Nat Nanotechnol. 2024 Mar; 19(3):354-363.
Udani S, Langerman J, Koo D, Baghdasarian S, Cheng B, Kang S, Soemardy C, de Rutte J, Plath K, Di Carlo D. PMID: 38082117; PMCID: PMC11452923.
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PubMed Mentions:
5 Fields:
Translation:
Cells
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H3K36 methylation maintains cell identity by regulating opposing lineage programmes. Nat Cell Biol. 2023 Aug; 25(8):1121-1134.
Hoetker MS, Yagi M, Di Stefano B, Langerman J, Cristea S, Wong LP, Huebner AJ, Charlton J, Deng W, Haggerty C, Sadreyev RI, Meissner A, Michor F, Plath K, Hochedlinger K. PMID: 37460697; PMCID: PMC10896483.
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PubMed Mentions:
10 Fields:
Translation:
Cells
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Nutrient regulation of development and cell fate decisions. Development. 2023 10 15; 150(20).
Tu WB, Christofk HR, Plath K. PMID: 37260407; PMCID: PMC10281554.
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PubMed Mentions:
2 Fields:
Translation:
Humans
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ZFP36-mediated mRNA decay regulates metabolism. Cell Rep. 2023 05 30; 42(5):112411.
Cicchetto AC, Jacobson EC, Sunshine H, Wilde BR, Krall AS, Jarrett KE, Sedgeman L, Turner M, Plath K, Iruela-Arispe ML, de Aguiar Vallim TQ, Christofk HR. PMID: 37086408; PMCID: PMC10332406.
View in:
PubMed Mentions:
4 Fields:
Translation:
Cells
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Secretion encoded single-cell sequencing (SEC-seq) uncovers gene expression signatures associated with high VEGF-A secretion in mesenchymal stromal cells. bioRxiv. 2023 Jan 08.
Udani S, Langerman J, Koo D, Baghdasarian S, Cheng B, Kang S, Soemardy C, de Rutte J, Plath K, Carlo DD. PMID: 36711480; PMCID: PMC9881958.
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PubMed Mentions:
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High-Field Asymmetric Waveform Ion Mobility Spectrometry Interface Enhances Parallel Reaction Monitoring on an Orbitrap Mass Spectrometer. Anal Chem. 2022 11 22; 94(46):15939-15947.
Deng W, Sha J, Xue F, Jami-Alahmadi Y, Plath K, Wohlschlegel J. PMID: 36347042; PMCID: PMC9685594.
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PubMed Mentions: Fields:
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Oct4:Sox2 binding is essential for establishing but not maintaining active and silent states of dynamically regulated genes in pluripotent cells. Genes Dev. 2022 10 01; 36(19-20):1079-1095.
Lo JH, Edwards M, Langerman J, Sridharan R, Plath K, Smale ST. PMID: 36418052; PMCID: PMC9744233.
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PubMed Mentions:
6 Fields:
Translation:
AnimalsCells
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TGFβ superfamily signaling regulates the state of human stem cell pluripotency and capacity to create well-structured telencephalic organoids. Stem Cell Reports. 2022 10 11; 17(10):2220-2238.
Watanabe M, Buth JE, Haney JR, Vishlaghi N, Turcios F, Elahi LS, Gu W, Pearson CA, Kurdian A, Baliaouri NV, Collier AJ, Miranda OA, Dunn N, Chen D, Sabri S, Torre-Ubieta L, Clark AT, Plath K, Christofk HR, Kornblum HI, Gandal MJ, Novitch BG. PMID: 36179695; PMCID: PMC9561534.
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PubMed Mentions:
13 Fields:
Translation:
HumansCells
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A lifelong duty: how Xist maintains the inactive X chromosome. Curr Opin Genet Dev. 2022 08; 75:101927.
Jacobson EC, Pandya-Jones A, Plath K. PMID: 35717799; PMCID: PMC9472561.
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PubMed Mentions:
11 Fields:
Translation:
HumansCells
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FGFR3 is expressed by human primordial germ cells and is repressed after meiotic initiation to form primordial oocytes. Stem Cell Reports. 2022 06 14; 17(6):1268-1278.
Chitiashvili T, Hsu FM, Dror I, Plath K, Clark A. PMID: 35594860; PMCID: PMC9214056.
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PubMed Mentions:
2 Fields:
Translation:
HumansCells
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Genome-wide screening identifies Polycomb repressive complex 1.3 as an essential regulator of human naïve pluripotent cell reprogramming. Sci Adv. 2022 03 25; 8(12):eabk0013.
Collier AJ, Bendall A, Fabian C, Malcolm AA, Tilgner K, Semprich CI, Wojdyla K, Nisi PS, Kishore K, Roamio Franklin VN, Mirshekar-Syahkal B, D'Santos C, Plath K, Yusa K, Rugg-Gunn PJ. PMID: 35333572; PMCID: PMC8956265.
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PubMed Mentions:
6 Fields:
Translation:
HumansCells
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Transcriptional, Electrophysiological, and Metabolic Characterizations of hESC-Derived First and Second Heart Fields Demonstrate a Potential Role of TBX5 in Cardiomyocyte Maturation. Front Cell Dev Biol. 2021; 9:787684.
Pezhouman A, Nguyen NB, Sercel AJ, Nguyen TL, Daraei A, Sabri S, Chapski DJ, Zheng M, Patananan AN, Ernst J, Plath K, Vondriska TM, Teitell MA, Ardehali R. PMID: 34988079; PMCID: PMC8722677.
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PubMed Mentions:
3
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Xist nucleates local protein gradients to propagate silencing across the X chromosome. Cell. 2021 Dec 09; 184(25):6212.
Markaki Y, Chong JG, Wang Y, Jacobson EC, Luong C, Tan SYX, Jachowicz JW, Strehle M, Maestrini D, Banerjee AK, Mistry BA, Dror I, Dossin F, Sch?neberg J, Heard E, Guttman M, Chou T, Plath K. PMID: 34890555; PMCID: PMC8722464.
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PubMed Mentions:
9 Fields:
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RNA promotes the formation of spatial compartments in the nucleus. Cell. 2021 11 11; 184(23):5775-5790.e30.
Quinodoz SA, Jachowicz JW, Bhat P, Ollikainen N, Banerjee AK, Goronzy IN, Blanco MR, Chovanec P, Chow A, Markaki Y, Thai J, Plath K, Guttman M. PMID: 34739832; PMCID: PMC9115877.
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PubMed Mentions:
134 Fields:
Translation:
HumansAnimalsCells
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Xist nucleates local protein gradients to propagate silencing across the X chromosome. Cell. 2021 12 09; 184(25):6174-6192.e32.
Markaki Y, Gan Chong J, Wang Y, Jacobson EC, Luong C, Tan SYX, Jachowicz JW, Strehle M, Maestrini D, Banerjee AK, Mistry BA, Dror I, Dossin F, Schöneberg J, Heard E, Guttman M, Chou T, Plath K. PMID: 34813726; PMCID: PMC8671326.
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PubMed Mentions:
41 Fields:
Translation:
HumansAnimalsCells
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Defining the nature of human pluripotent stem cell-derived interneurons via single-cell analysis. Stem Cell Reports. 2021 10 12; 16(10):2548-2564.
Allison T, Langerman J, Sabri S, Otero-Garcia M, Lund A, Huang J, Wei X, Samarasinghe RA, Polioudakis D, Mody I, Cobos I, Novitch BG, Geschwind DH, Plath K, Lowry WE. PMID: 34506726; PMCID: PMC8514853.
View in:
PubMed Mentions:
4 Fields:
Translation:
HumansCells
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Identification of neural oscillations and epileptiform changes in human brain organoids. Nat Neurosci. 2021 10; 24(10):1488-1500.
Samarasinghe RA, Miranda OA, Buth JE, Mitchell S, Ferando I, Watanabe M, Allison TF, Kurdian A, Fotion NN, Gandal MJ, Golshani P, Plath K, Lowry WE, Parent JM, Mody I, Novitch BG. PMID: 34426698; PMCID: PMC9070733.
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PubMed Mentions:
101 Fields:
Translation:
HumansCells
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Divergent roles for KLF4 and TFCP2L1 in naive ground state pluripotency and human primordial germ cell development. Stem Cell Res. 2021 08; 55:102493.
Hancock GV, Liu W, Peretz L, Chen D, Gell JJ, Collier AJ, Zamudio JR, Plath K, Clark AT. PMID: 34399163; PMCID: PMC8969886.
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PubMed Mentions:
4 Fields:
Translation:
HumansCells
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The transcription factor code in iPSC reprogramming. Curr Opin Genet Dev. 2021 10; 70:89-96.
Deng W, Jacobson EC, Collier AJ, Plath K. PMID: 34246082; PMCID: PMC9469655.
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PubMed Mentions:
14 Fields:
Translation:
HumansAnimalsCells
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Transcriptional analysis of cystic fibrosis airways at single-cell resolution reveals altered epithelial cell states and composition. Nat Med. 2021 05; 27(5):806-814.
Carraro G, Langerman J, Sabri S, Lorenzana Z, Purkayastha A, Zhang G, Konda B, Aros CJ, Calvert BA, Szymaniak A, Wilson E, Mulligan M, Bhatt P, Lu J, Vijayaraj P, Yao C, Shia DW, Lund AJ, Israely E, Rickabaugh TM, Ernst J, Mense M, Randell SH, Vladar EK, Ryan AL, Plath K, Mahoney JE, Stripp BR, Gomperts BN. PMID: 33958799; PMCID: PMC9009537.
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PubMed Mentions:
76 Fields:
Translation:
HumansCells
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SARS-CoV-2 infection rewires host cell metabolism and is potentially susceptible to mTORC1 inhibition. Nat Commun. 2021 03 25; 12(1):1876.
Mullen PJ, Garcia G, Purkayastha A, Matulionis N, Schmid EW, Momcilovic M, Sen C, Langerman J, Ramaiah A, Shackelford DB, Damoiseaux R, French SW, Plath K, Gomperts BN, Arumugaswami V, Christofk HR. PMID: 33767183; PMCID: PMC7994801.
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PubMed Mentions:
73 Fields:
Translation:
HumansAnimalsCells
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Carboxylate-Modified Magnetic Bead (CMMB)-Based Isopropanol Gradient Peptide Fractionation (CIF) Enables Rapid and Robust Off-Line Peptide Mixture Fractionation in Bottom-Up Proteomics. Mol Cell Proteomics. 2021; 20:100039.
Deng W, Sha J, Plath K, Wohlschlegel JA. PMID: 33476790; PMCID: PMC7950212.
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PubMed Mentions:
5 Fields:
Translation:
HumansCells
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Single-cell analysis of the developing human testis reveals somatic niche cell specification and fetal germline stem cell establishment. Cell Stem Cell. 2021 04 01; 28(4):764-778.e4.
Guo J, Sosa E, Chitiashvili T, Nie X, Rojas EJ, Oliver E, DonorConnect, Plath K, Hotaling JM, Stukenborg JB, Clark AT, Cairns BR. PMID: 33453151; PMCID: PMC8026516.
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PubMed Mentions:
74 Fields:
Translation:
HumansCells
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Pressure-Driven Mitochondrial Transfer Pipeline Generates Mammalian Cells of Desired Genetic Combinations and Fates. Cell Rep. 2020 12 29; 33(13):108562.
Patananan AN, Sercel AJ, Wu TH, Ahsan FM, Torres A, Kennedy SAL, Vandiver A, Collier AJ, Mehrabi A, Van Lew J, Zakin L, Rodriguez N, Sixto M, Tadros W, Lazar A, Sieling PA, Nguyen TL, Dawson ER, Braas D, Golovato J, Cisneros L, Vaske C, Plath K, Rabizadeh S, Niazi KR, Chiou PY, Teitell MA. PMID: 33378680; PMCID: PMC7927156.
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PubMed Mentions:
17 Fields:
Translation:
HumansAnimalsCells
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Chromatin and Nuclear Architecture in Stem Cells. Stem Cell Reports. 2020 12 08; 15(6):1155-1157.
Meshorer E, Plath K. PMID: 33296671; PMCID: PMC7724516.
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PubMed Mentions:
1 Fields:
Translation:
HumansAnimalsCells
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Female human primordial germ cells display X-chromosome dosage compensation despite the absence of X-inactivation. Nat Cell Biol. 2020 12; 22(12):1436-1446.
Chitiashvili T, Dror I, Kim R, Hsu FM, Chaudhari R, Pandolfi E, Chen D, Liebscher S, Schenke-Layland K, Plath K, Clark A. PMID: 33257808; PMCID: PMC7717582.
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PubMed Mentions:
34 Fields:
Translation:
HumansCells
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Direct Exposure to SARS-CoV-2 and Cigarette Smoke Increases Infection Severity and Alters the Stem Cell-Derived Airway Repair Response. Cell Stem Cell. 2020 12 03; 27(6):869-875.e4.
Purkayastha A, Sen C, Garcia G, Langerman J, Shia DW, Meneses LK, Vijayaraj P, Durra A, Koloff CR, Freund DR, Chi J, Rickabaugh TM, Mulay A, Konda B, Sim MS, Stripp BR, Plath K, Arumugaswami V, Gomperts BN. PMID: 33259798; PMCID: PMC7670932.
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PubMed Mentions:
50 Fields:
Translation:
HumansCells
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Publisher Correction: A protein assembly mediates Xist localization and gene silencing. Nature. 2020 Oct; 586(7830):E30.
Pandya-Jones A, Markaki Y, Serizay J, Chitiashvili T, Leon WRM, Damianov A, Chronis C, Papp B, Chen CK, McKee R, Wang XJ, Chau A, Sabri S, Leonhardt H, Zheng S, Guttman M, Black DL, Plath K. PMID: 33005055.
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PubMed Mentions:
2 Fields:
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A protein assembly mediates Xist localization and gene silencing. Nature. 2020 11; 587(7832):145-151.
Pandya-Jones A, Markaki Y, Serizay J, Chitiashvili T, Mancia Leon WR, Damianov A, Chronis C, Papp B, Chen CK, McKee R, Wang XJ, Chau A, Sabri S, Leonhardt H, Zheng S, Guttman M, Black DL, Plath K. PMID: 32908311; PMCID: PMC7644664.
View in:
PubMed Mentions:
87 Fields:
Translation:
HumansAnimalsCells
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Direct exposure to SARS-CoV-2 and cigarette smoke increases infection severity and alters the stem cell-derived airway repair response. bioRxiv. 2020 Jul 29.
Purkayastha A, Sen C, Garcia G, Langerman J, Vijayaraj P, Shia DW, Meneses LK, Rickabaugh TM, Mulay A, Konda B, Sim MS, Stripp BR, Plath K, Arumugaswami V, Gomperts BN. PMID: 32766588; PMCID: PMC7402049.
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PubMed Mentions:
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A Human Skeletal Muscle Atlas Identifies the Trajectories of Stem and Progenitor Cells across Development and from Human Pluripotent Stem Cells. Cell Stem Cell. 2020 Jul 02; 27(1):181-185.
Xi H, Langerman J, Sabri S, Chien P, Young CS, Younesi S, Hicks M, Gonzalez K, Fujiwara W, Marzi J, Liebscher S, Spencer M, Van Handel B, Evseenko D, Schenke-Layland K, Plath K, Pyle AD. PMID: 32619514; PMCID: PMC9012334.
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PubMed Mentions:
25 Fields:
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A Human Skeletal Muscle Atlas Identifies the Trajectories of Stem and Progenitor Cells across Development and from Human Pluripotent Stem Cells. Cell Stem Cell. 2020 07 02; 27(1):158-176.e10.
Xi H, Langerman J, Sabri S, Chien P, Young CS, Younesi S, Hicks M, Gonzalez K, Fujiwara W, Marzi J, Liebscher S, Spencer M, Van Handel B, Evseenko D, Schenke-Layland K, Plath K, Pyle AD. PMID: 32396864; PMCID: PMC7367475.
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PubMed Mentions:
53 Fields:
Translation:
HumansCells
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Defining Transcriptional Signatures of Human Hair Follicle Cell States. J Invest Dermatol. 2020 04; 140(4):764-773.e4.
Takahashi R, Grzenda A, Allison TF, Rawnsley J, Balin SJ, Sabri S, Plath K, Lowry WE. PMID: 31676413; PMCID: PMC7093259.
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PubMed Mentions:
35 Fields:
Translation:
HumansAnimalsCells
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A Single-Cell Transcriptomic Atlas of Human Neocortical Development during Mid-gestation. Neuron. 2019 09 04; 103(5):785-801.e8.
Polioudakis D, de la Torre-Ubieta L, Langerman J, Elkins AG, Shi X, Stein JL, Vuong CK, Nichterwitz S, Gevorgian M, Opland CK, Lu D, Connell W, Ruzzo EK, Lowe JK, Hadzic T, Hinz FI, Sabri S, Lowry WE, Gerstein MB, Plath K, Geschwind DH. PMID: 31303374; PMCID: PMC6831089.
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PubMed Mentions:
211 Fields:
Translation:
HumansCells
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DNA methylation estimation using methylation-sensitive restriction enzyme bisulfite sequencing (MREBS). PLoS One. 2019; 14(4):e0214368.
Bonora G, Rubbi L, Morselli M, Ma F, Chronis C, Plath K, Pellegrini M. PMID: 30946758; PMCID: PMC6448829.
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PubMed Mentions:
9 Fields:
Translation:
AnimalsCells
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The BAF and PRC2 Complex Subunits Dpf2 and Eed Antagonistically Converge on Tbx3 to Control ESC Differentiation. Cell Stem Cell. 2019 01 03; 24(1):138-152.e8.
Zhang W, Chronis C, Chen X, Zhang H, Spalinskas R, Pardo M, Chen L, Wu G, Zhu Z, Yu Y, Yu L, Choudhary J, Nichols J, Parast MM, Greber B, Sahlén P, Plath K. PMID: 30609396; PMCID: PMC6486830.
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PubMed Mentions:
22 Fields:
Translation:
AnimalsCells
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Comparison of reprogramming factor targets reveals both species-specific and conserved mechanisms in early iPSC reprogramming. BMC Genomics. 2018 Dec 22; 19(1):956.
Fu K, Chronis C, Soufi A, Bonora G, Edwards M, Smale ST, Zaret KS, Plath K, Pellegrini M. PMID: 30577748; PMCID: PMC6303873.
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PubMed Mentions:
9 Fields:
Translation:
HumansAnimalsCells
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Promoter-Enhancer Communication Occurs Primarily within Insulated Neighborhoods. Mol Cell. 2019 01 17; 73(2):250-263.e5.
Sun F, Chronis C, Kronenberg M, Chen XF, Su T, Lay FD, Plath K, Kurdistani SK, Carey MF. PMID: 30527662; PMCID: PMC6338517.
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PubMed Mentions:
46 Fields:
Translation:
AnimalsCells
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Reduced MEK inhibition preserves genomic stability in naive human embryonic stem cells. Nat Methods. 2018 09; 15(9):732-740.
Di Stefano B, Ueda M, Sabri S, Brumbaugh J, Huebner AJ, Sahakyan A, Clement K, Clowers KJ, Erickson AR, Shioda K, Gygi SP, Gu H, Shioda T, Meissner A, Takashima Y, Plath K, Hochedlinger K. PMID: 30127506; PMCID: PMC6127858.
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PubMed Mentions:
48 Fields:
Translation:
HumansCells
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Mapping Metabolism: Monitoring Lactate Dehydrogenase Activity Directly in Tissue. J Vis Exp. 2018 06 21; (136).
Jelinek D, Flores A, Uebelhoer M, Pasque V, Plath K, Iruela-Arispe ML, Christofk HR, Lowry WE, Coller HA. PMID: 29985359; PMCID: PMC6101961.
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PubMed Mentions:
5 Fields:
Translation:
Animals
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The Role of Xist in X-Chromosome Dosage Compensation. Trends Cell Biol. 2018 12; 28(12):999-1013.
Sahakyan A, Yang Y, Plath K. PMID: 29910081; PMCID: PMC6249047.
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PubMed Mentions:
75 Fields:
Translation:
HumansAnimalsCells
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Identification and Single-Cell Functional Characterization of an Endodermally Biased Pluripotent Substate in Human Embryonic Stem Cells. Stem Cell Reports. 2018 06 05; 10(6):1895-1907.
Allison TF, Smith AJH, Anastassiadis K, Sloane-Stanley J, Biga V, Stavish D, Hackland J, Sabri S, Langerman J, Jones M, Plath K, Coca D, Barbaric I, Gokhale P, Andrews PW. PMID: 29779895; PMCID: PMC5993559.
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PubMed Mentions:
17 Fields:
Translation:
HumansCells
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Loss of MECP2 Leads to Activation of P53 and Neuronal Senescence. Stem Cell Reports. 2018 05 08; 10(5):1453-1463.
Ohashi M, Korsakova E, Allen D, Lee P, Fu K, Vargas BS, Cinkornpumin J, Salas C, Park JC, Germanguz I, Langerman J, Chronis C, Kuoy E, Tran S, Xiao X, Pellegrini M, Plath K, Lowry WE. PMID: 29742391; PMCID: PMC5995366.
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PubMed Mentions:
39 Fields:
Translation:
HumansCells
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X Chromosome Dosage Influences DNA Methylation Dynamics during Reprogramming to Mouse iPSCs. Stem Cell Reports. 2018 05 08; 10(5):1537-1550.
Pasque V, Karnik R, Chronis C, Petrella P, Langerman J, Bonora G, Song J, Vanheer L, Sadhu Dimashkie A, Meissner A, Plath K. PMID: 29681539; PMCID: PMC5995367.
View in:
PubMed Mentions:
22 Fields:
Translation:
AnimalsCells
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Correction: Epigenetic resetting of human pluripotency (doi:10.1242/dev.146811). Development. 2018 04 18; 145(8).
Guo G, von Meyenn F, Rostovskaya M, Clarke J, Dietmann S, Baker D, Sahakyan A, Myers S, Bertone P, Reik W, Plath K, Smith A. PMID: 29669738; PMCID: PMC5964655.
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PubMed Mentions:
1 Fields:
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Analysis of cardiomyocyte clonal expansion during mouse heart development and injury. Nat Commun. 2018 02 21; 9(1):754.
Sereti KI, Nguyen NB, Kamran P, Zhao P, Ranjbarvaziri S, Park S, Sabri S, Engel JL, Sung K, Kulkarni RP, Ding Y, Hsiai TK, Plath K, Ernst J, Sahoo D, Mikkola HKA, Iruela-Arispe ML, Ardehali R. PMID: 29467410; PMCID: PMC5821855.
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PubMed Mentions:
57 Fields:
Translation:
AnimalsCells
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High-Throughput Screening of a Luciferase Reporter of Gene Silencing on the Inactive X Chromosome. Methods Mol Biol. 2018; 1755:75-87.
Keegan A, Plath K, Damoiseaux R. PMID: 29671264.
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PubMed Mentions: Fields:
Translation:
AnimalsCells
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Regulation of X-chromosome dosage compensation in human: mechanisms and model systems. Philos Trans R Soc Lond B Biol Sci. 2017 Nov 05; 372(1733).
Sahakyan A, Plath K, Rougeulle C. PMID: 28947660; PMCID: PMC5627163.
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PubMed Mentions:
19 Fields:
Translation:
HumansAnimalsCells
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Epigenetic resetting of human pluripotency. Development. 2017 08 01; 144(15):2748-2763.
Guo G, von Meyenn F, Rostovskaya M, Clarke J, Dietmann S, Baker D, Sahakyan A, Myers S, Bertone P, Reik W, Plath K, Smith A. PMID: 28765214; PMCID: PMC5560041.
View in:
PubMed Mentions:
135 Fields:
Translation:
HumansAnimalsCells
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Cbx3 maintains lineage specificity during neural differentiation. Genes Dev. 2017 02 01; 31(3):241-246.
Huang C, Su T, Xue Y, Cheng C, Lay FD, McKee RA, Li M, Vashisht A, Wohlschlegel J, Novitch BG, Plath K, Kurdistani SK, Carey M. PMID: 28270516; PMCID: PMC5358721.
View in:
PubMed Mentions:
27 Fields:
Translation:
AnimalsCells
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Cooperative Binding of Transcription Factors Orchestrates Reprogramming. Cell. 2017 01 26; 168(3):442-459.e20.
Chronis C, Fiziev P, Papp B, Butz S, Bonora G, Sabri S, Ernst J, Plath K. PMID: 28111071; PMCID: PMC5302508.
View in:
PubMed Mentions:
271 Fields:
Translation:
AnimalsCells
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Human Embryonic Stem Cells Do Not Change Their X Inactivation Status during Differentiation. Cell Rep. 2017 01 03; 18(1):54-67.
Patel S, Bonora G, Sahakyan A, Kim R, Chronis C, Langerman J, Fitz-Gibbon S, Rubbi L, Skelton RJP, Ardehali R, Pellegrini M, Lowry WE, Clark AT, Plath K. PMID: 27989715; PMCID: PMC5214931.
View in:
PubMed Mentions:
54 Fields:
Translation:
HumansCells
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Human Naive Pluripotent Stem Cells Model X Chromosome Dampening and X Inactivation. Cell Stem Cell. 2017 01 05; 20(1):87-101.
Sahakyan A, Kim R, Chronis C, Sabri S, Bonora G, Theunissen TW, Kuoy E, Langerman J, Clark AT, Jaenisch R, Plath K. PMID: 27989770; PMCID: PMC5218861.
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118 Fields:
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HumansCells
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Glycolytic Metabolism Plays a Functional Role in Regulating Human Pluripotent Stem Cell State. Cell Stem Cell. 2016 10 06; 19(4):476-490.
Gu W, Gaeta X, Sahakyan A, Chan AB, Hong CS, Kim R, Braas D, Plath K, Lowry WE, Christofk HR. PMID: 27618217; PMCID: PMC5055460.
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146 Fields:
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HumansAnimalsCells
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Transcriptome Encyclopedia of Early Human Development. Cell. 2016 May 05; 165(4):777-9.
Sahakyan A, Plath K. PMID: 27153491; PMCID: PMC4859939.
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8 Fields:
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HumansAnimalsCells
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The "lnc" between 3D chromatin structure and X chromosome inactivation. Semin Cell Dev Biol. 2016 08; 56:35-47.
Pandya-Jones A, Plath K. PMID: 27062886; PMCID: PMC4955722.
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14 Fields:
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HumansAnimalsCells
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Naive Human Pluripotent Cells Feature a Methylation Landscape Devoid of Blastocyst or Germline Memory. Cell Stem Cell. 2016 Mar 03; 18(3):323-329.
Pastor WA, Chen D, Liu W, Kim R, Sahakyan A, Lukianchikov A, Plath K, Jacobsen SE, Clark AT. PMID: 26853856; PMCID: PMC4779431.
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PubMed Mentions:
149 Fields:
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HumansAnimalsCells
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X chromosome reactivation in reprogramming and in development. Curr Opin Cell Biol. 2015 Dec; 37:75-83.
Pasque V, Plath K. PMID: 26540406; PMCID: PMC4688236.
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29 Fields:
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HumansAnimalsCells
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A high-throughput screen of inactive X chromosome reactivation identifies the enhancement of DNA demethylation by 5-aza-2'-dC upon inhibition of ribonucleotide reductase. Epigenetics Chromatin. 2015; 8:42.
Minkovsky A, Sahakyan A, Bonora G, Damoiseaux R, Dimitrova E, Rubbi L, Pellegrini M, Radu CG, Plath K. PMID: 26468331; PMCID: PMC4604769.
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24 Fields:
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The Xist lncRNA interacts directly with SHARP to silence transcription through HDAC3. Nature. 2015 May 14; 521(7551):232-6.
McHugh CA, Chen CK, Chow A, Surka CF, Tran C, McDonel P, Pandya-Jones A, Blanco M, Burghard C, Moradian A, Sweredoski MJ, Shishkin AA, Su J, Lander ES, Hess S, Plath K, Guttman M. PMID: 25915022; PMCID: PMC4516396.
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PubMed Mentions:
582 Fields:
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AnimalsCells
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X chromosome reactivation dynamics reveal stages of reprogramming to pluripotency. Cell. 2014 Dec 18; 159(7):1681-97.
Pasque V, Tchieu J, Karnik R, Uyeda M, Sadhu Dimashkie A, Case D, Papp B, Bonora G, Patel S, Ho R, Schmidt R, McKee R, Sado T, Tada T, Meissner A, Plath K. PMID: 25525883; PMCID: PMC4282187.
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53 Fields:
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AnimalsCells
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A mechanistic link between gene regulation and genome architecture in mammalian development. Curr Opin Genet Dev. 2014 Aug; 27:92-101.
Bonora G, Plath K, Denholtz M. PMID: 24998386; PMCID: PMC4125518.
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24 Fields:
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HumansAnimalsCells
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The Mbd1-Atf7ip-Setdb1 pathway contributes to the maintenance of X chromosome inactivation. Epigenetics Chromatin. 2014; 7:12.
Minkovsky A, Sahakyan A, Rankin-Gee E, Bonora G, Patel S, Plath K. PMID: 25028596; PMCID: PMC4099106.
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39 Fields:
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Long-range chromatin contacts in embryonic stem cells reveal a role for pluripotency factors and polycomb proteins in genome organization. Cell Stem Cell. 2013 Nov 07; 13(5):602-16.
Denholtz M, Bonora G, Chronis C, Splinter E, de Laat W, Ernst J, Pellegrini M, Plath K. PMID: 24035354; PMCID: PMC3825755.
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PubMed Mentions:
151 Fields:
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AnimalsCells
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Initial characterization of histone H3 serine 10 O-acetylation. Epigenetics. 2013 Oct; 8(10):1101-13.
Britton LM, Newhart A, Bhanu NV, Sridharan R, Gonzales-Cope M, Plath K, Janicki SM, Garcia BA. PMID: 23949383; PMCID: PMC3891691.
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PubMed Mentions:
15 Fields:
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HumansAnimalsCells
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The Xist lncRNA exploits three-dimensional genome architecture to spread across the X chromosome. Science. 2013 Aug 16; 341(6147):1237973.
Engreitz JM, Pandya-Jones A, McDonel P, Shishkin A, Sirokman K, Surka C, Kadri S, Xing J, Goren A, Lander ES, Plath K, Guttman M. PMID: 23828888; PMCID: PMC3778663.
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PubMed Mentions:
531 Fields:
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AnimalsCells
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A new route to human embryonic stem cells. Nat Med. 2013 Jul; 19(7):820-1.
Trounson A, Daley GQ, Pasque V, Plath K. PMID: 23836223.
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PubMed Mentions:
2 Fields:
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HumansCells
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Stage-specific regulation of reprogramming to induced pluripotent stem cells by Wnt signaling and T cell factor proteins. Cell Rep. 2013 Jun 27; 3(6):2113-26.
Ho R, Papp B, Hoffman JA, Merrill BJ, Plath K. PMID: 23791530; PMCID: PMC3700671.
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PubMed Mentions:
53 Fields:
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AnimalsCells
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Proteomic and genomic approaches reveal critical functions of H3K9 methylation and heterochromatin protein-1γ in reprogramming to pluripotency. Nat Cell Biol. 2013 Jul; 15(7):872-82.
Sridharan R, Gonzales-Cope M, Chronis C, Bonora G, McKee R, Huang C, Patel S, Lopez D, Mishra N, Pellegrini M, Carey M, Garcia BA, Plath K. PMID: 23748610; PMCID: PMC3733997.
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PubMed Mentions:
139 Fields:
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AnimalsCells
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The pluripotency factor-bound intron 1 of Xist is dispensable for X chromosome inactivation and reactivation in vitro and in vivo. Cell Rep. 2013 Mar 28; 3(3):905-18.
Minkovsky A, Barakat TS, Sellami N, Chin MH, Gunhanlar N, Gribnau J, Plath K. PMID: 23523354; PMCID: PMC3615097.
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PubMed Mentions:
26 Fields:
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AnimalsCells
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Epigenetics of reprogramming to induced pluripotency. Cell. 2013 Mar 14; 152(6):1324-43.
Papp B, Plath K. PMID: 23498940; PMCID: PMC3602907.
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163 Fields:
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HumansAnimalsCells
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Pluripotency in 3D: genome organization in pluripotent cells. Curr Opin Cell Biol. 2012 Dec; 24(6):793-801.
Denholtz M, Plath K. PMID: 23199754; PMCID: PMC3540188.
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PubMed Mentions:
12 Fields:
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HumansAnimalsCells
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Mediator and SAGA have distinct roles in Pol II preinitiation complex assembly and function. Cell Rep. 2012 Nov 29; 2(5):1061-7.
Chen XF, Lehmann L, Lin JJ, Vashisht A, Schmidt R, Ferrari R, Huang C, McKee R, Mosley A, Plath K, Kurdistani SK, Wohlschlegel J, Carey M. PMID: 23177621; PMCID: PMC3513640.
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24 Fields:
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HumansAnimalsCells
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PubMed Mentions:
1 Fields:
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HumansCells
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The roles of the reprogramming factors Oct4, Sox2 and Klf4 in resetting the somatic cell epigenome during induced pluripotent stem cell generation. Genome Biol. 2012 Oct 22; 13(10):251.
Schmidt R, Plath K. PMID: 23088445; PMCID: PMC3491406.
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PubMed Mentions:
52 Fields:
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HumansAnimalsCells
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Cell reprogramming. Curr Opin Genet Dev. 2012 Oct; 22(5):401-2.
Pera MF, Plath K. PMID: 23084811.
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HumansAnimalsCells
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Pluripotency re-centered around Esrrb. EMBO J. 2012 Nov 14; 31(22):4255-7.
Papp B, Plath K. PMID: 23064149; PMCID: PMC3501223.
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PubMed Mentions:
9 Fields:
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AnimalsCells
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Characterization and therapeutic potential of induced pluripotent stem cell-derived cardiovascular progenitor cells. PLoS One. 2012; 7(10):e45603.
Nsair A, Schenke-Layland K, Van Handel B, Evseenko D, Kahn M, Zhao P, Mendelis J, Heydarkhan S, Awaji O, Vottler M, Geist S, Chyu J, Gago-Lopez N, Crooks GM, Plath K, Goldhaber J, Mikkola HK, MacLellan WR. PMID: 23056209; PMCID: PMC3467279.
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PubMed Mentions:
23 Fields:
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AnimalsCells
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Concise review: Pluripotency and the transcriptional inactivation of the female Mammalian X chromosome. Stem Cells. 2012 Jan; 30(1):48-54.
Minkovsky A, Patel S, Plath K. PMID: 21997775; PMCID: PMC3251695.
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29 Fields:
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HumansAnimalsCells
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From skin biopsy to neurons through a pluripotent intermediate under Good Manufacturing Practice protocols. Stem Cells Transl Med. 2012 Jan; 1(1):36-43.
Karumbayaram S, Lee P, Azghadi SF, Cooper AR, Patterson M, Kohn DB, Pyle A, Clark A, Byrne J, Zack JA, Plath K, Lowry WE. PMID: 23197638; PMCID: PMC3727693.
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PubMed Mentions:
30 Fields:
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HumansAnimalsCells
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Derivation of new human embryonic stem cell lines reveals rapid epigenetic progression in vitro that can be prevented by chemical modification of chromatin. Hum Mol Genet. 2012 Feb 15; 21(4):751-64.
Diaz Perez SV, Kim R, Li Z, Marquez VE, Patel S, Plath K, Clark AT. PMID: 22058289; PMCID: PMC3263987.
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PubMed Mentions:
35 Fields:
Translation:
HumansCells
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Mediator coordinates PIC assembly with recruitment of CHD1. Genes Dev. 2011 Oct 15; 25(20):2198-209.
Lin JJ, Lehmann LW, Bonora G, Sridharan R, Vashisht AA, Tran N, Plath K, Wohlschlegel JA, Carey M. PMID: 21979373; PMCID: PMC3205589.
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PubMed Mentions:
65 Fields:
Translation:
HumansAnimalsCells
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Highly efficient large-scale lentiviral vector concentration by tandem tangential flow filtration. J Virol Methods. 2011 Oct; 177(1):1-9.
Cooper AR, Patel S, Senadheera S, Plath K, Kohn DB, Hollis RP. PMID: 21784103; PMCID: PMC4276401.
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PubMed Mentions:
38 Fields:
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HumansAnimalsCells
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Small RNAs loom large during reprogramming. Cell Stem Cell. 2011 Jun 03; 8(6):599-601.
Sridharan R, Plath K. PMID: 21624799; PMCID: PMC3612285.
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6 Fields:
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Mechanistic insights into reprogramming to induced pluripotency. J Cell Physiol. 2011 Apr; 226(4):868-78.
Ho R, Chronis C, Plath K. PMID: 20945378; PMCID: PMC3077549.
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PubMed Mentions:
23 Fields:
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HumansAnimalsCells
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Progress in understanding reprogramming to the induced pluripotent state. Nat Rev Genet. 2011 Apr; 12(4):253-65.
Plath K, Lowry WE. PMID: 21415849; PMCID: PMC3273493.
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145 Fields:
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HumansAnimalsCells
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Reprogramming to pluripotency: stepwise resetting of the epigenetic landscape. Cell Res. 2011 Mar; 21(3):486-501.
Papp B, Plath K. PMID: 21321600; PMCID: PMC3193418.
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PubMed Mentions:
88 Fields:
Translation:
Cells
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Identification and classification of chromosomal aberrations in human induced pluripotent stem cells. Cell Stem Cell. 2010 Oct 08; 7(4):521-31.
Mayshar Y, Ben-David U, Lavon N, Biancotti JC, Yakir B, Clark AT, Plath K, Lowry WE, Benvenisty N. PMID: 20887957.
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PubMed Mentions:
374 Fields:
Translation:
HumansCells
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Identification of context-dependent motifs by contrasting ChIP binding data. Bioinformatics. 2010 Nov 15; 26(22):2826-32.
Mason MJ, Plath K, Zhou Q. PMID: 20870645; PMCID: PMC2971577.
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PubMed Mentions:
20 Fields:
Translation:
AnimalsCells
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Female human iPSCs retain an inactive X chromosome. Cell Stem Cell. 2010 Sep 03; 7(3):329-42.
Tchieu J, Kuoy E, Chin MH, Trinh H, Patterson M, Sherman SP, Aimiuwu O, Lindgren A, Hakimian S, Zack JA, Clark AT, Pyle AD, Lowry WE, Plath K. PMID: 20727844; PMCID: PMC2935700.
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PubMed Mentions:
142 Fields:
Translation:
HumansCells
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Molecular analyses of human induced pluripotent stem cells and embryonic stem cells. Cell Stem Cell. 2010 Aug 06; 7(2):263-9.
Chin MH, Pellegrini M, Plath K, Lowry WE. PMID: 20682452; PMCID: PMC3276111.
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75 Fields:
Translation:
HumansCells
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Transcriptional competence and the active marking of tissue-specific enhancers by defined transcription factors in embryonic and induced pluripotent stem cells. Genes Dev. 2009 Dec 15; 23(24):2824-38.
Xu J, Watts JA, Pope SD, Gadue P, Kamps M, Plath K, Zaret KS, Smale ST. PMID: 20008934; PMCID: PMC2800090.
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PubMed Mentions:
102 Fields:
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AnimalsCells
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Genome-wide dynamics of replication timing revealed by in vitro models of mouse embryogenesis. Genome Res. 2010 Feb; 20(2):155-69.
Hiratani I, Ryba T, Itoh M, Rathjen J, Kulik M, Papp B, Fussner E, Bazett-Jones DP, Plath K, Dalton S, Rathjen PD, Gilbert DM. PMID: 19952138; PMCID: PMC2813472.
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PubMed Mentions:
181 Fields:
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AnimalsCells
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Signed weighted gene co-expression network analysis of transcriptional regulation in murine embryonic stem cells. BMC Genomics. 2009 Jul 20; 10:327.
Mason MJ, Fan G, Plath K, Zhou Q, Horvath S. PMID: 19619308; PMCID: PMC2727539.
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124 Fields:
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AnimalsCells
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Chd1 regulates open chromatin and pluripotency of embryonic stem cells. Nature. 2009 Aug 13; 460(7257):863-8.
Gaspar-Maia A, Alajem A, Polesso F, Sridharan R, Mason MJ, Heidersbach A, Ramalho-Santos J, McManus MT, Plath K, Meshorer E, Ramalho-Santos M. PMID: 19587682; PMCID: PMC3891576.
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PubMed Mentions:
275 Fields:
Translation:
AnimalsCells
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Induced pluripotent stem cells and embryonic stem cells are distinguished by gene expression signatures. Cell Stem Cell. 2009 Jul 02; 5(1):111-23.
Chin MH, Mason MJ, Xie W, Volinia S, Singer M, Peterson C, Ambartsumyan G, Aimiuwu O, Richter L, Zhang J, Khvorostov I, Ott V, Grunstein M, Lavon N, Benvenisty N, Croce CM, Clark AT, Baxter T, Pyle AD, Teitell MA, Pelegrini M, Plath K, Lowry WE. PMID: 19570518; PMCID: PMC3448781.
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PubMed Mentions:
458 Fields:
Translation:
HumansAnimalsCells
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Derivation of primordial germ cells from human embryonic and induced pluripotent stem cells is significantly improved by coculture with human fetal gonadal cells. Stem Cells. 2009 Apr; 27(4):783-95.
Park TS, Galic Z, Conway AE, Lindgren A, van Handel BJ, Magnusson M, Richter L, Teitell MA, Mikkola HK, Lowry WE, Plath K, Clark AT. PMID: 19350678; PMCID: PMC4357362.
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PubMed Mentions:
98 Fields:
Translation:
HumansCells
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Directed differentiation of human-induced pluripotent stem cells generates active motor neurons. Stem Cells. 2009 Apr; 27(4):806-11.
Karumbayaram S, Novitch BG, Patterson M, Umbach JA, Richter L, Lindgren A, Conway AE, Clark AT, Goldman SA, Plath K, Wiedau-Pazos M, Kornblum HI, Lowry WE. PMID: 19350680; PMCID: PMC2895909.
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155 Fields:
Translation:
HumansCells
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Broader implications of defining standards for the pluripotency of iPSCs. Cell Stem Cell. 2009 Mar 06; 4(3):200-1; author reply 202.
Daley GQ, Lensch MW, Jaenisch R, Meissner A, Plath K, Yamanaka S. PMID: 19265657.
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PubMed Mentions:
55 Fields:
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HumansAnimalsCells
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Histone h3 lysine 56 acetylation is linked to the core transcriptional network in human embryonic stem cells. Mol Cell. 2009 Feb 27; 33(4):417-27.
Xie W, Song C, Young NL, Sperling AS, Xu F, Sridharan R, Conway AE, Garcia BA, Plath K, Clark AT, Grunstein M. PMID: 19250903; PMCID: PMC2671231.
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PubMed Mentions:
119 Fields:
Translation:
HumansAnimalsCells
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Post-translational regulation of Oct4 transcriptional activity. PLoS One. 2009; 4(2):e4467.
Saxe JP, Tomilin A, Schöler HR, Plath K, Huang J. PMID: 19221599; PMCID: PMC2637973.
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PubMed Mentions:
60 Fields:
Translation:
AnimalsCells
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Epigenetic reprogramming and induced pluripotency. Development. 2009 Feb; 136(4):509-23.
Hochedlinger K, Plath K. PMID: 19168672; PMCID: PMC2685952.
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PubMed Mentions:
232 Fields:
Translation:
HumansAnimalsCells
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Role of the murine reprogramming factors in the induction of pluripotency. Cell. 2009 Jan 23; 136(2):364-77.
Sridharan R, Tchieu J, Mason MJ, Yachechko R, Kuoy E, Horvath S, Zhou Q, Plath K. PMID: 19167336; PMCID: PMC3273494.
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PubMed Mentions:
356 Fields:
Translation:
AnimalsCells
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X chromosome inactivation in the absence of Dicer. Proc Natl Acad Sci U S A. 2009 Jan 27; 106(4):1122-7.
Kanellopoulou C, Muljo SA, Dimitrov SD, Chen X, Colin C, Plath K, Livingston DM. PMID: 19164542; PMCID: PMC2633553.
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PubMed Mentions:
24 Fields:
Translation:
AnimalsCells
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The many ways to make an iPS cell. Nat Biotechnol. 2008 Nov; 26(11):1246-8.
Lowry WE, Plath K. PMID: 18997764.
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14 Fields:
Translation:
HumansAnimalsCells
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Dynamics of vibrational overtone excited pyruvic acid in the gas phase: line broadening through hydrogen-atom chattering. J Phys Chem A. 2008 Aug 14; 112(32):7321-31.
Takahashi K, Plath KL, Skodje RT, Vaida V. PMID: 18637664.
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6 Fields:
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Reprogrammed mouse fibroblasts differentiate into cells of the cardiovascular and hematopoietic lineages. Stem Cells. 2008 Jun; 26(6):1537-46.
Schenke-Layland K, Rhodes KE, Angelis E, Butylkova Y, Heydarkhan-Hagvall S, Gekas C, Zhang R, Goldhaber JI, Mikkola HK, Plath K, MacLellan WR. PMID: 18450826; PMCID: PMC2873147.
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PubMed Mentions:
87 Fields:
Translation:
AnimalsCells
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Illuminating the black box of reprogramming. Cell Stem Cell. 2008 Apr 10; 2(4):295-7.
Sridharan R, Plath K. PMID: 18397745.
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9 Fields:
Translation:
HumansAnimalsCells
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Generation of human induced pluripotent stem cells from dermal fibroblasts. Proc Natl Acad Sci U S A. 2008 Feb 26; 105(8):2883-8.
Lowry WE, Richter L, Yachechko R, Pyle AD, Tchieu J, Sridharan R, Clark AT, Plath K. PMID: 18287077; PMCID: PMC2268554.
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PubMed Mentions:
432 Fields:
Translation:
HumansCells
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Directly reprogrammed fibroblasts show global epigenetic remodeling and widespread tissue contribution. Cell Stem Cell. 2007 Jun 07; 1(1):55-70.
Maherali N, Sridharan R, Xie W, Utikal J, Eminli S, Arnold K, Stadtfeld M, Yachechko R, Tchieu J, Jaenisch R, Plath K, Hochedlinger K. PMID: 18371336.
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PubMed Mentions:
707 Fields:
Translation:
AnimalsCells
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The histone domain of macroH2A1 contains several dispersed elements that are each sufficient to direct enrichment on the inactive X chromosome. J Mol Biol. 2007 Aug 03; 371(1):11-8.
Nusinow DA, Sharp JA, Morris A, Salas S, Plath K, Panning B. PMID: 17570398; PMCID: PMC2701898.
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16 Fields:
Translation:
HumansCells
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A bivalent chromatin structure marks key developmental genes in embryonic stem cells. Cell. 2006 Apr 21; 125(2):315-26.
Bernstein BE, Mikkelsen TS, Xie X, Kamal M, Huebert DJ, Cuff J, Fry B, Meissner A, Wernig M, Plath K, Jaenisch R, Wagschal A, Feil R, Schreiber SL, Lander ES. PMID: 16630819.
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PubMed Mentions:
2731 Fields:
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AnimalsCells
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Polycomb complexes repress developmental regulators in murine embryonic stem cells. Nature. 2006 May 18; 441(7091):349-53.
Boyer LA, Plath K, Zeitlinger J, Brambrink T, Medeiros LA, Lee TI, Levine SS, Wernig M, Tajonar A, Ray MK, Bell GW, Otte AP, Vidal M, Gifford DK, Young RA, Jaenisch R. PMID: 16625203.
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1285 Fields:
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AnimalsCells
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Efficient method to generate single-copy transgenic mice by site-specific integration in embryonic stem cells. Genesis. 2006 Jan; 44(1):23-8.
Beard C, Hochedlinger K, Plath K, Wutz A, Jaenisch R. PMID: 16400644.
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PubMed Mentions:
295 Fields:
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AnimalsCells
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Mapping post-translational modifications of the histone variant MacroH2A1 using tandem mass spectrometry. Mol Cell Proteomics. 2006 Jan; 5(1):194-203.
Chu F, Nusinow DA, Chalkley RJ, Plath K, Panning B, Burlingame AL. PMID: 16210244.
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37 Fields:
Translation:
Cells
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Developmental regulation of Suz 12 localization. Chromosoma. 2005 Aug; 114(3):183-92.
de la Cruz CC, Fang J, Plath K, Worringer KA, Nusinow DA, Zhang Y, Panning B. PMID: 15986205.
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PubMed Mentions:
10 Fields:
Translation:
HumansAnimalsCells
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Developmentally regulated alterations in Polycomb repressive complex 1 proteins on the inactive X chromosome. J Cell Biol. 2004 Dec 20; 167(6):1025-35.
Plath K, Talbot D, Hamer KM, Otte AP, Yang TP, Jaenisch R, Panning B. PMID: 15596546; PMCID: PMC2172612.
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60 Fields:
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HumansAnimalsCells
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Interactions between Sec complex and prepro-alpha-factor during posttranslational protein transport into the endoplasmic reticulum. Mol Biol Cell. 2004 Jan; 15(1):1-10.
Plath K, Wilkinson BM, Stirling CJ, Rapoport TA. PMID: 14617809; PMCID: PMC307522.
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PubMed Mentions:
22 Fields:
Translation:
AnimalsCells
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Role of histone H3 lysine 27 methylation in X inactivation. Science. 2003 Apr 04; 300(5616):131-5.
Plath K, Fang J, Mlynarczyk-Evans SK, Cao R, Worringer KA, Wang H, de la Cruz CC, Otte AP, Panning B, Zhang Y. PMID: 12649488.
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PubMed Mentions:
548 Fields:
Translation:
HumansAnimalsCells
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Xist RNA and the mechanism of X chromosome inactivation. Annu Rev Genet. 2002; 36:233-78.
Plath K, Mlynarczyk-Evans S, Nusinow DA, Panning B. PMID: 12429693.
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192 Fields:
Translation:
AnimalsCells
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The structure of ribosome-channel complexes engaged in protein translocation. Mol Cell. 2000 Nov; 6(5):1219-32.
Menetret JF, Neuhof A, Morgan DG, Plath K, Radermacher M, Rapoport TA, Akey CW. PMID: 11106759.
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61 Fields:
Translation:
AnimalsCells
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Spontaneous release of cytosolic proteins from posttranslational substrates before their transport into the endoplasmic reticulum. J Cell Biol. 2000 Oct 02; 151(1):167-78.
Plath K, Rapoport TA. PMID: 11018062; PMCID: PMC2189806.
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PubMed Mentions:
27 Fields:
Translation:
AnimalsCells
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Posttranslational protein translocation across the membrane of the endoplasmic reticulum. Biol Chem. 1999 Oct; 380(10):1143-50.
Rapoport TA, Matlack KE, Plath K, Misselwitz B, Staeck O. PMID: 10595576.
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29 Fields:
Translation:
HumansAnimalsCells
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BiP acts as a molecular ratchet during posttranslational transport of prepro-alpha factor across the ER membrane. Cell. 1999 May 28; 97(5):553-64.
Matlack KE, Misselwitz B, Plath K, Rapoport TA. PMID: 10367885.
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PubMed Mentions:
146 Fields:
Translation:
AnimalsCells
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Signal sequence recognition in posttranslational protein transport across the yeast ER membrane. Cell. 1998 Sep 18; 94(6):795-807.
Plath K, Mothes W, Wilkinson BM, Stirling CJ, Rapoport TA. PMID: 9753326.
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PubMed Mentions:
132 Fields:
Translation:
AnimalsCells
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Protein transport by purified yeast Sec complex and Kar2p without membranes. Science. 1997 Aug 15; 277(5328):938-41.
Matlack KE, Plath K, Misselwitz B, Rapoport TA. PMID: 9252322.
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PubMed Mentions:
29 Fields:
Translation:
Cells
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Oligomeric rings of the Sec61p complex induced by ligands required for protein translocation. Cell. 1996 Nov 15; 87(4):721-32.
Hanein D, Matlack KE, Jungnickel B, Plath K, Kalies KU, Miller KR, Rapoport TA, Akey CW. PMID: 8929540.
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PubMed Mentions:
98 Fields:
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AnimalsCells
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A second trimeric complex containing homologs of the Sec61p complex functions in protein transport across the ER membrane of S. cerevisiae. EMBO J. 1996 Apr 01; 15(7):1482-94.
Finke K, Plath K, Panzner S, Prehn S, Rapoport TA, Hartmann E, Sommer T. PMID: 8612571; PMCID: PMC450055.
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PubMed Mentions:
60 Fields:
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AnimalsCells
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Constitutive activation of mitogen-activated protein kinase-activated protein kinase 2 by mutation of phosphorylation sites and an A-helix motif. J Biol Chem. 1995 Nov 10; 270(45):27213-21.
Engel K, Schultz H, Martin F, Kotlyarov A, Plath K, Hahn M, Heinemann U, Gaestel M. PMID: 7592979.
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PubMed Mentions:
46 Fields:
Translation:
AnimalsCells
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Characterization of the proline-rich region of mouse MAPKAP kinase 2: influence on catalytic properties and binding to the c-abl SH3 domain in vitro. Biochem Biophys Res Commun. 1994 Sep 15; 203(2):1188-94.
Plath K, Engel K, Schwedersky G, Gaestel M. PMID: 8093038.
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PubMed Mentions:
5 Fields:
Translation:
HumansAnimalsCells
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The MAP kinase-activated protein kinase 2 contains a proline-rich SH3-binding domain. FEBS Lett. 1993 Dec 20; 336(1):143-7.
Engel K, Plath K, Gaestel M. PMID: 8262198.
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PubMed Mentions:
11 Fields:
Translation:
Cells