Kathrin Plath

Title(s)Professor, Biological Chemistry
SchoolMedicine
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    Epigenetic control of the human X chromosome
    NIH R01HD098387May 1, 2019 - Apr 30, 2024
    Role: Principal Investigator
    Defining the role of the E3-ligase APC/C and ubiquitination in X-inactivation
    NIH R21HD094172Apr 1, 2018 - Mar 31, 2020
    Role: Principal Investigator
    Elucidating an Xist-dependent program of sexually dimorphic alternative splicing in the mammalian brain
    NIH R01MH109166Jul 1, 2016 - Apr 30, 2021
    Role: Co-Principal Investigator
    Mechanism of chromatin remodeling and gene silencing by the lncRNAs Xist and Tsix
    NIH R01GM115233Aug 1, 2015 - Jun 30, 2019
    Role: Principal Investigator
    Reprogramming Genetic Networks to a Pluripotent State
    NIH P01GM099134Aug 1, 2011 - Apr 30, 2022
    Role: Principal Investigator
    CHROMATIN AND EPIGENETIC INHERITANCE
    NIH DP2OD001686Sep 30, 2007 - Aug 31, 2012
    Role: Principal Investigator

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    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. The transcription factor code in iPSC reprogramming. Curr Opin Genet Dev. 2021 Jul 07; 70:89-96. Deng W, Jacobson EC, Collier AJ, Plath K. PMID: 34246082.
      View in: PubMed   Mentions:    Fields:    
    2. SARS-CoV-2 infection rewires host cell metabolism and is potentially susceptible to mTORC1 inhibition. Nat Commun. 2021 03 25; 12(1):1876. Mullen PJ, Garcia G, Purkayastha A, Matulionis N, Schmid EW, Momcilovic M, Sen C, Langerman J, Ramaiah A, Shackelford DB, Damoiseaux R, French SW, Plath K, Gomperts BN, Arumugaswami V, Christofk HR. PMID: 33767183.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimalsCells
    3. Carboxylate-Modified Magnetic Bead (CMMB)-Based Isopropanol Gradient Peptide Fractionation (CIF) Enables Rapid and Robust Off-Line Peptide Mixture Fractionation in Bottom-Up Proteomics. Mol Cell Proteomics. 2021 Jan 19; 20:100039. Deng W, Sha J, Plath K, Wohlschlegel JA. PMID: 33476790.
      View in: PubMed   Mentions:    Fields:    
    4. Pressure-Driven Mitochondrial Transfer Pipeline Generates Mammalian Cells of Desired Genetic Combinations and Fates. Cell Rep. 2020 12 29; 33(13):108562. Patananan AN, Sercel AJ, Wu TH, Ahsan FM, Torres A, Kennedy SAL, Vandiver A, Collier AJ, Mehrabi A, Van Lew J, Zakin L, Rodriguez N, Sixto M, Tadros W, Lazar A, Sieling PA, Nguyen TL, Dawson ER, Braas D, Golovato J, Cisneros L, Vaske C, Plath K, Rabizadeh S, Niazi KR, Chiou PY, Teitell MA. PMID: 33378680.
      View in: PubMed   Mentions: 2     Fields:    
    5. Female human primordial germ cells display X-chromosome dosage compensation despite the absence of X-inactivation. Nat Cell Biol. 2020 12; 22(12):1436-1446. Chitiashvili T, Dror I, Kim R, Hsu FM, Chaudhari R, Pandolfi E, Chen D, Liebscher S, Schenke-Layland K, Plath K, Clark A. PMID: 33257808.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCells
    6. Direct Exposure to SARS-CoV-2 and Cigarette Smoke Increases Infection Severity and Alters the Stem Cell-Derived Airway Repair Response. Cell Stem Cell. 2020 12 03; 27(6):869-875.e4. Purkayastha A, Sen C, Garcia G, Langerman J, Shia DW, Meneses LK, Vijayaraj P, Durra A, Koloff CR, Freund DR, Chi J, Rickabaugh TM, Mulay A, Konda B, Sim MS, Stripp BR, Plath K, Arumugaswami V, Gomperts BN. PMID: 33259798.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansCells
    7. Publisher Correction: A protein assembly mediates Xist localization and gene silencing. Nature. 2020 Oct; 586(7830):E30. Pandya-Jones A, Markaki Y, Serizay J, Chitiashvili T, Leon WRM, Damianov A, Chronis C, Papp B, Chen CK, McKee R, Wang XJ, Chau A, Sabri S, Leonhardt H, Zheng S, Guttman M, Black DL, Plath K. PMID: 33005055.
      View in: PubMed   Mentions:    Fields:    
    8. A protein assembly mediates Xist localization and gene silencing. Nature. 2020 11; 587(7832):145-151. Pandya-Jones A, Markaki Y, Serizay J, Chitiashvili T, Mancia Leon WR, Damianov A, Chronis C, Papp B, Chen CK, McKee R, Wang XJ, Chau A, Sabri S, Leonhardt H, Zheng S, Guttman M, Black DL, Plath K. PMID: 32908311.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansAnimalsCells
    9. A Human Skeletal Muscle Atlas Identifies the Trajectories of Stem and Progenitor Cells across Development and from Human Pluripotent Stem Cells. Cell Stem Cell. 2020 07 02; 27(1):158-176.e10. Xi H, Langerman J, Sabri S, Chien P, Young CS, Younesi S, Hicks M, Gonzalez K, Fujiwara W, Marzi J, Liebscher S, Spencer M, Van Handel B, Evseenko D, Schenke-Layland K, Plath K, Pyle AD. PMID: 32396864.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
    10. Defining Transcriptional Signatures of Human Hair Follicle Cell States. J Invest Dermatol. 2020 04; 140(4):764-773.e4. Takahashi R, Grzenda A, Allison TF, Rawnsley J, Balin SJ, Sabri S, Plath K, Lowry WE. PMID: 31676413.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimalsCells
    11. A Single-Cell Transcriptomic Atlas of Human Neocortical Development during Mid-gestation. Neuron. 2019 09 04; 103(5):785-801.e8. Polioudakis D, de la Torre-Ubieta L, Langerman J, Elkins AG, Shi X, Stein JL, Vuong CK, Nichterwitz S, Gevorgian M, Opland CK, Lu D, Connell W, Ruzzo EK, Lowe JK, Hadzic T, Hinz FI, Sabri S, Lowry WE, Gerstein MB, Plath K, Geschwind DH. PMID: 31303374.
      View in: PubMed   Mentions: 51     Fields:    Translation:HumansCells
    12. DNA methylation estimation using methylation-sensitive restriction enzyme bisulfite sequencing (MREBS). PLoS One. 2019; 14(4):e0214368. Bonora G, Rubbi L, Morselli M, Ma F, Chronis C, Plath K, Pellegrini M. PMID: 30946758.
      View in: PubMed   Mentions: 4     Fields:    Translation:AnimalsCells
    13. Comparison of reprogramming factor targets reveals both species-specific and conserved mechanisms in early iPSC reprogramming. BMC Genomics. 2018 Dec 22; 19(1):956. Fu K, Chronis C, Soufi A, Bonora G, Edwards M, Smale ST, Zaret KS, Plath K, Pellegrini M. PMID: 30577748.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimalsCells
    14. Promoter-Enhancer Communication Occurs Primarily within Insulated Neighborhoods. Mol Cell. 2019 01 17; 73(2):250-263.e5. Sun F, Chronis C, Kronenberg M, Chen XF, Su T, Lay FD, Plath K, Kurdistani SK, Carey MF. PMID: 30527662.
      View in: PubMed   Mentions: 18     Fields:    Translation:AnimalsCells
    15. Mapping Metabolism: Monitoring Lactate Dehydrogenase Activity Directly in Tissue. J Vis Exp. 2018 06 21; (136). Jelinek D, Flores A, Uebelhoer M, Pasque V, Plath K, Iruela-Arispe ML, Christofk HR, Lowry WE, Coller HA. PMID: 29985359.
      View in: PubMed   Mentions: 1     Fields:    Translation:Animals
    16. The Role of Xist in X-Chromosome Dosage Compensation. Trends Cell Biol. 2018 12; 28(12):999-1013. Sahakyan A, Yang Y, Plath K. PMID: 29910081.
      View in: PubMed   Mentions: 33     Fields:    Translation:HumansAnimalsCells
    17. Loss of MECP2 Leads to Activation of P53 and Neuronal Senescence. Stem Cell Reports. 2018 05 08; 10(5):1453-1463. Ohashi M, Korsakova E, Allen D, Lee P, Fu K, Vargas BS, Cinkornpumin J, Salas C, Park JC, Germanguz I, Langerman J, Chronis C, Kuoy E, Tran S, Xiao X, Pellegrini M, Plath K, Lowry WE. PMID: 29742391.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansCells
    18. X Chromosome Dosage Influences DNA Methylation Dynamics during Reprogramming to Mouse iPSCs. Stem Cell Reports. 2018 05 08; 10(5):1537-1550. Pasque V, Karnik R, Chronis C, Petrella P, Langerman J, Bonora G, Song J, Vanheer L, Sadhu Dimashkie A, Meissner A, Plath K. PMID: 29681539.
      View in: PubMed   Mentions: 7     Fields:    Translation:AnimalsCells
    19. Analysis of cardiomyocyte clonal expansion during mouse heart development and injury. Nat Commun. 2018 02 21; 9(1):754. Sereti KI, Nguyen NB, Kamran P, Zhao P, Ranjbarvaziri S, Park S, Sabri S, Engel JL, Sung K, Kulkarni RP, Ding Y, Hsiai TK, Plath K, Ernst J, Sahoo D, Mikkola HKA, Iruela-Arispe ML, Ardehali R. PMID: 29467410.
      View in: PubMed   Mentions: 29     Fields:    Translation:AnimalsCells
    20. High-Throughput Screening of a Luciferase Reporter of Gene Silencing on the Inactive X Chromosome. Methods Mol Biol. 2018; 1755:75-87. Keegan A, Plath K, Damoiseaux R. PMID: 29671264.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    21. Regulation of X-chromosome dosage compensation in human: mechanisms and model systems. Philos Trans R Soc Lond B Biol Sci. 2017 Nov 05; 372(1733). Sahakyan A, Plath K, Rougeulle C. PMID: 28947660.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansAnimalsCells
    22. Cbx3 maintains lineage specificity during neural differentiation. Genes Dev. 2017 02 01; 31(3):241-246. Huang C, Su T, Xue Y, Cheng C, Lay FD, McKee RA, Li M, Vashisht A, Wohlschlegel J, Novitch BG, Plath K, Kurdistani SK, Carey M. PMID: 28270516.
      View in: PubMed   Mentions: 12     Fields:    Translation:AnimalsCells
    23. Cooperative Binding of Transcription Factors Orchestrates Reprogramming. Cell. 2017 01 26; 168(3):442-459.e20. Chronis C, Fiziev P, Papp B, Butz S, Bonora G, Sabri S, Ernst J, Plath K. PMID: 28111071.
      View in: PubMed   Mentions: 132     Fields:    Translation:AnimalsCells
    24. Human Embryonic Stem Cells Do Not Change Their X Inactivation Status during Differentiation. Cell Rep. 2017 01 03; 18(1):54-67. Patel S, Bonora G, Sahakyan A, Kim R, Chronis C, Langerman J, Fitz-Gibbon S, Rubbi L, Skelton RJP, Ardehali R, Pellegrini M, Lowry WE, Clark AT, Plath K. PMID: 27989715.
      View in: PubMed   Mentions: 31     Fields:    Translation:HumansCells
    25. Human Naive Pluripotent Stem Cells Model X Chromosome Dampening and X Inactivation. Cell Stem Cell. 2017 01 05; 20(1):87-101. Sahakyan A, Kim R, Chronis C, Sabri S, Bonora G, Theunissen TW, Kuoy E, Langerman J, Clark AT, Jaenisch R, Plath K. PMID: 27989770.
      View in: PubMed   Mentions: 66     Fields:    Translation:HumansCells
    26. Glycolytic Metabolism Plays a Functional Role in Regulating Human Pluripotent Stem Cell State. Cell Stem Cell. 2016 10 06; 19(4):476-490. Gu W, Gaeta X, Sahakyan A, Chan AB, Hong CS, Kim R, Braas D, Plath K, Lowry WE, Christofk HR. PMID: 27618217.
      View in: PubMed   Mentions: 76     Fields:    Translation:HumansAnimalsCells
    27. Transcriptome Encyclopedia of Early Human Development. Cell. 2016 May 05; 165(4):777-9. Sahakyan A, Plath K. PMID: 27153491.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimalsCells
    28. The "lnc" between 3D chromatin structure and X chromosome inactivation. Semin Cell Dev Biol. 2016 08; 56:35-47. Pandya-Jones A, Plath K. PMID: 27062886.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimalsCells
    29. X chromosome reactivation in reprogramming and in development. Curr Opin Cell Biol. 2015 Dec; 37:75-83. Pasque V, Plath K. PMID: 26540406.
      View in: PubMed   Mentions: 21     Fields:    Translation:HumansAnimalsCells
    30. A high-throughput screen of inactive X chromosome reactivation identifies the enhancement of DNA demethylation by 5-aza-2'-dC upon inhibition of ribonucleotide reductase. Epigenetics Chromatin. 2015; 8:42. Minkovsky A, Sahakyan A, Bonora G, Damoiseaux R, Dimitrova E, Rubbi L, Pellegrini M, Radu CG, Plath K. PMID: 26468331.
      View in: PubMed   Mentions: 17     Fields:    
    31. X chromosome reactivation dynamics reveal stages of reprogramming to pluripotency. Cell. 2014 Dec 18; 159(7):1681-97. Pasque V, Tchieu J, Karnik R, Uyeda M, Sadhu Dimashkie A, Case D, Papp B, Bonora G, Patel S, Ho R, Schmidt R, McKee R, Sado T, Tada T, Meissner A, Plath K. PMID: 25525883.
      View in: PubMed   Mentions: 35     Fields:    Translation:AnimalsCells
    32. A mechanistic link between gene regulation and genome architecture in mammalian development. Curr Opin Genet Dev. 2014 Aug; 27:92-101. Bonora G, Plath K, Denholtz M. PMID: 24998386.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansAnimalsCells
    33. The Mbd1-Atf7ip-Setdb1 pathway contributes to the maintenance of X chromosome inactivation. Epigenetics Chromatin. 2014; 7:12. Minkovsky A, Sahakyan A, Rankin-Gee E, Bonora G, Patel S, Plath K. PMID: 25028596.
      View in: PubMed   Mentions: 23     Fields:    
    34. Long-range chromatin contacts in embryonic stem cells reveal a role for pluripotency factors and polycomb proteins in genome organization. Cell Stem Cell. 2013 Nov 07; 13(5):602-16. Denholtz M, Bonora G, Chronis C, Splinter E, de Laat W, Ernst J, Pellegrini M, Plath K. PMID: 24035354.
      View in: PubMed   Mentions: 99     Fields:    Translation:AnimalsCells
    35. Initial characterization of histone H3 serine 10 O-acetylation. Epigenetics. 2013 Oct; 8(10):1101-13. Britton LM, Newhart A, Bhanu NV, Sridharan R, Gonzales-Cope M, Plath K, Janicki SM, Garcia BA. PMID: 23949383.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansAnimalsCells
    36. The Xist lncRNA exploits three-dimensional genome architecture to spread across the X chromosome. Science. 2013 Aug 16; 341(6147):1237973. Engreitz JM, Pandya-Jones A, McDonel P, Shishkin A, Sirokman K, Surka C, Kadri S, Xing J, Goren A, Lander ES, Plath K, Guttman M. PMID: 23828888.
      View in: PubMed   Mentions: 362     Fields:    Translation:AnimalsCells
    37. A new route to human embryonic stem cells. Nat Med. 2013 Jul; 19(7):820-1. Trounson A, Daley GQ, Pasque V, Plath K. PMID: 23836223.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    38. Stage-specific regulation of reprogramming to induced pluripotent stem cells by Wnt signaling and T cell factor proteins. Cell Rep. 2013 Jun 27; 3(6):2113-26. Ho R, Papp B, Hoffman JA, Merrill BJ, Plath K. PMID: 23791530.
      View in: PubMed   Mentions: 42     Fields:    Translation:AnimalsCells
    39. Proteomic and genomic approaches reveal critical functions of H3K9 methylation and heterochromatin protein-1? in reprogramming to pluripotency. Nat Cell Biol. 2013 Jul; 15(7):872-82. Sridharan R, Gonzales-Cope M, Chronis C, Bonora G, McKee R, Huang C, Patel S, Lopez D, Mishra N, Pellegrini M, Carey M, Garcia BA, Plath K. PMID: 23748610.
      View in: PubMed   Mentions: 98     Fields:    Translation:AnimalsCells
    40. The pluripotency factor-bound intron 1 of Xist is dispensable for X chromosome inactivation and reactivation in vitro and in vivo. Cell Rep. 2013 Mar 28; 3(3):905-18. Minkovsky A, Barakat TS, Sellami N, Chin MH, Gunhanlar N, Gribnau J, Plath K. PMID: 23523354.
      View in: PubMed   Mentions: 19     Fields:    Translation:AnimalsCells
    41. Epigenetics of reprogramming to induced pluripotency. Cell. 2013 Mar 14; 152(6):1324-43. Papp B, Plath K. PMID: 23498940.
      View in: PubMed   Mentions: 129     Fields:    Translation:HumansAnimalsCells
    42. Pluripotency in 3D: genome organization in pluripotent cells. Curr Opin Cell Biol. 2012 Dec; 24(6):793-801. Denholtz M, Plath K. PMID: 23199754.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansAnimalsCells
    43. Mediator and SAGA have distinct roles in Pol II preinitiation complex assembly and function. Cell Rep. 2012 Nov 29; 2(5):1061-7. Chen XF, Lehmann L, Lin JJ, Vashisht A, Schmidt R, Ferrari R, Huang C, McKee R, Mosley A, Plath K, Kurdistani SK, Wohlschlegel J, Carey M. PMID: 23177621.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansAnimalsCells
    44. Stem cells in the land of the rising sun: ISSCR 2012. Cell Stem Cell. 2012 Nov 02; 11(5):607-14. Plath K, Srivastava D, Alvarez-Buylla A, Tanaka EM, Kriegstein AR. PMID: 23122288.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    45. The roles of the reprogramming factors Oct4, Sox2 and Klf4 in resetting the somatic cell epigenome during induced pluripotent stem cell generation. Genome Biol. 2012 Oct 22; 13(10):251. Schmidt R, Plath K. PMID: 23088445.
      View in: PubMed   Mentions: 34     Fields:    Translation:HumansAnimalsCells
    46. Cell reprogramming. Curr Opin Genet Dev. 2012 Oct; 22(5):401-2. Pera MF, Plath K. PMID: 23084811.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    47. Pluripotency re-centered around Esrrb. EMBO J. 2012 Nov 14; 31(22):4255-7. Papp B, Plath K. PMID: 23064149.
      View in: PubMed   Mentions: 8     Fields:    Translation:AnimalsCells
    48. Characterization and therapeutic potential of induced pluripotent stem cell-derived cardiovascular progenitor cells. PLoS One. 2012; 7(10):e45603. Nsair A, Schenke-Layland K, Van Handel B, Evseenko D, Kahn M, Zhao P, Mendelis J, Heydarkhan S, Awaji O, Vottler M, Geist S, Chyu J, Gago-Lopez N, Crooks GM, Plath K, Goldhaber J, Mikkola HK, MacLellan WR. PMID: 23056209.
      View in: PubMed   Mentions: 21     Fields:    Translation:AnimalsCells
    49. Concise review: Pluripotency and the transcriptional inactivation of the female Mammalian X chromosome. Stem Cells. 2012 Jan; 30(1):48-54. Minkovsky A, Patel S, Plath K. PMID: 21997775.
      View in: PubMed   Mentions: 25     Fields:    Translation:HumansAnimalsCells
    50. From skin biopsy to neurons through a pluripotent intermediate under Good Manufacturing Practice protocols. Stem Cells Transl Med. 2012 Jan; 1(1):36-43. Karumbayaram S, Lee P, Azghadi SF, Cooper AR, Patterson M, Kohn DB, Pyle A, Clark A, Byrne J, Zack JA, Plath K, Lowry WE. PMID: 23197638.
      View in: PubMed   Mentions: 25     Fields:    Translation:HumansAnimalsCells
    51. Derivation of new human embryonic stem cell lines reveals rapid epigenetic progression in vitro that can be prevented by chemical modification of chromatin. Hum Mol Genet. 2012 Feb 15; 21(4):751-64. Diaz Perez SV, Kim R, Li Z, Marquez VE, Patel S, Plath K, Clark AT. PMID: 22058289.
      View in: PubMed   Mentions: 23     Fields:    Translation:HumansCells
    52. Mediator coordinates PIC assembly with recruitment of CHD1. Genes Dev. 2011 Oct 15; 25(20):2198-209. Lin JJ, Lehmann LW, Bonora G, Sridharan R, Vashisht AA, Tran N, Plath K, Wohlschlegel JA, Carey M. PMID: 21979373.
      View in: PubMed   Mentions: 55     Fields:    Translation:HumansAnimalsCells
    53. Small RNAs loom large during reprogramming. Cell Stem Cell. 2011 Jun 03; 8(6):599-601. Sridharan R, Plath K. PMID: 21624799.
      View in: PubMed   Mentions: 6     Fields:    
    54. Progress in understanding reprogramming to the induced pluripotent state. Nat Rev Genet. 2011 Apr; 12(4):253-65. Plath K, Lowry WE. PMID: 21415849.
      View in: PubMed   Mentions: 124     Fields:    Translation:HumansAnimalsCells
    55. Mechanistic insights into reprogramming to induced pluripotency. J Cell Physiol. 2011 Apr; 226(4):868-78. Ho R, Chronis C, Plath K. PMID: 20945378.
      View in: PubMed   Mentions: 21     Fields:    Translation:HumansAnimalsCells
    56. Reprogramming to pluripotency: stepwise resetting of the epigenetic landscape. Cell Res. 2011 Mar; 21(3):486-501. Papp B, Plath K. PMID: 21321600.
      View in: PubMed   Mentions: 76     Fields:    Translation:Cells
    57. Identification and classification of chromosomal aberrations in human induced pluripotent stem cells. Cell Stem Cell. 2010 Oct 08; 7(4):521-31. Mayshar Y, Ben-David U, Lavon N, Biancotti JC, Yakir B, Clark AT, Plath K, Lowry WE, Benvenisty N. PMID: 20887957.
      View in: PubMed   Mentions: 316     Fields:    Translation:HumansCells
    58. Identification of context-dependent motifs by contrasting ChIP binding data. Bioinformatics. 2010 Nov 15; 26(22):2826-32. Mason MJ, Plath K, Zhou Q. PMID: 20870645.
      View in: PubMed   Mentions: 19     Fields:    Translation:AnimalsCells
    59. Female human iPSCs retain an inactive X chromosome. Cell Stem Cell. 2010 Sep 03; 7(3):329-42. Tchieu J, Kuoy E, Chin MH, Trinh H, Patterson M, Sherman SP, Aimiuwu O, Lindgren A, Hakimian S, Zack JA, Clark AT, Pyle AD, Lowry WE, Plath K. PMID: 20727844.
      View in: PubMed   Mentions: 122     Fields:    Translation:HumansCells
    60. Molecular analyses of human induced pluripotent stem cells and embryonic stem cells. Cell Stem Cell. 2010 Aug 06; 7(2):263-9. Chin MH, Pellegrini M, Plath K, Lowry WE. PMID: 20682452.
      View in: PubMed   Mentions: 70     Fields:    Translation:HumansCells
    61. Transcriptional competence and the active marking of tissue-specific enhancers by defined transcription factors in embryonic and induced pluripotent stem cells. Genes Dev. 2009 Dec 15; 23(24):2824-38. Xu J, Watts JA, Pope SD, Gadue P, Kamps M, Plath K, Zaret KS, Smale ST. PMID: 20008934.
      View in: PubMed   Mentions: 89     Fields:    Translation:AnimalsCells
    62. Genome-wide dynamics of replication timing revealed by in vitro models of mouse embryogenesis. Genome Res. 2010 Feb; 20(2):155-69. Hiratani I, Ryba T, Itoh M, Rathjen J, Kulik M, Papp B, Fussner E, Bazett-Jones DP, Plath K, Dalton S, Rathjen PD, Gilbert DM. PMID: 19952138.
      View in: PubMed   Mentions: 150     Fields:    Translation:AnimalsCells
    63. Signed weighted gene co-expression network analysis of transcriptional regulation in murine embryonic stem cells. BMC Genomics. 2009 Jul 20; 10:327. Mason MJ, Fan G, Plath K, Zhou Q, Horvath S. PMID: 19619308.
      View in: PubMed   Mentions: 91     Fields:    Translation:AnimalsCells
    64. Chd1 regulates open chromatin and pluripotency of embryonic stem cells. Nature. 2009 Aug 13; 460(7257):863-8. Gaspar-Maia A, Alajem A, Polesso F, Sridharan R, Mason MJ, Heidersbach A, Ramalho-Santos J, McManus MT, Plath K, Meshorer E, Ramalho-Santos M. PMID: 19587682.
      View in: PubMed   Mentions: 242     Fields:    Translation:AnimalsCells
    65. Induced pluripotent stem cells and embryonic stem cells are distinguished by gene expression signatures. Cell Stem Cell. 2009 Jul 02; 5(1):111-23. Chin MH, Mason MJ, Xie W, Volinia S, Singer M, Peterson C, Ambartsumyan G, Aimiuwu O, Richter L, Zhang J, Khvorostov I, Ott V, Grunstein M, Lavon N, Benvenisty N, Croce CM, Clark AT, Baxter T, Pyle AD, Teitell MA, Pelegrini M, Plath K, Lowry WE. PMID: 19570518.
      View in: PubMed   Mentions: 439     Fields:    Translation:HumansAnimalsCells
    66. Derivation of primordial germ cells from human embryonic and induced pluripotent stem cells is significantly improved by coculture with human fetal gonadal cells. Stem Cells. 2009 Apr; 27(4):783-95. Park TS, Galic Z, Conway AE, Lindgren A, van Handel BJ, Magnusson M, Richter L, Teitell MA, Mikkola HK, Lowry WE, Plath K, Clark AT. PMID: 19350678.
      View in: PubMed   Mentions: 80     Fields:    Translation:HumansCells
    67. Directed differentiation of human-induced pluripotent stem cells generates active motor neurons. Stem Cells. 2009 Apr; 27(4):806-11. Karumbayaram S, Novitch BG, Patterson M, Umbach JA, Richter L, Lindgren A, Conway AE, Clark AT, Goldman SA, Plath K, Wiedau-Pazos M, Kornblum HI, Lowry WE. PMID: 19350680.
      View in: PubMed   Mentions: 132     Fields:    Translation:HumansCells
    68. Histone h3 lysine 56 acetylation is linked to the core transcriptional network in human embryonic stem cells. Mol Cell. 2009 Feb 27; 33(4):417-27. Xie W, Song C, Young NL, Sperling AS, Xu F, Sridharan R, Conway AE, Garcia BA, Plath K, Clark AT, Grunstein M. PMID: 19250903.
      View in: PubMed   Mentions: 103     Fields:    Translation:HumansAnimalsCells
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