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Selective regulation of a defined subset of inflammatory and immunoregulatory genes by an NF-kB p50-IkBzeta pathway. Genes & Develoopment. 2024; 38(11-12):536-553.
Daly AE, Yeh G, Soltero S, Smale ST.
-
Opposing tumor-cell-intrinsic and -extrinsic roles of the IRF1 transcription factor in antitumor immunity. Cell Rep. 2024 Jun 25; 43(6):114289.
Purbey PK, Seo J, Paul MK, Iwamoto KS, Daly AE, Feng AC, Champhekar AS, Langerman J, Campbell KM, Schaue D, McBride WH, Dubinett SM, Ribas A, Smale ST, Scumpia PO. PMID: 38833371; PMCID: PMC11315447.
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PubMed Mentions:
3 Fields:
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Alternative splicing of a chromatin modifier alters the transcriptional regulatory programs of stem cell maintenance and neuronal differentiation. Cell Stem Cell. 2024 May 02; 31(5):754-771.e6.
Nazim M, Lin CH, Feng AC, Xiao W, Yeom KH, Li M, Daly AE, Tan X, Vu H, Ernst J, Carey MF, Smale ST, Black DL. PMID: 38701759; PMCID: PMC11126784.
View in:
PubMed Mentions:
2 Fields:
Translation:
HumansAnimalsCells
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The transcription factor NF-κB orchestrates nucleosome remodeling during the primary response to Toll-like receptor 4 signaling. Immunity. 2024 Mar 12; 57(3):462-477.e9.
Feng AC, Thomas BJ, Purbey PK, de Melo FM, Liu X, Daly AE, Sun F, Lo JH, Cheng L, Carey MF, Scumpia PO, Smale ST. PMID: 38430908; PMCID: PMC10984581.
View in:
PubMed Mentions:
6 Fields:
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IL-10 constrains sphingolipid metabolism to limit inflammation. Nature. 2024 Mar; 627(8004):628-635.
York AG, Skadow MH, Oh J, Qu R, Zhou QD, Hsieh WY, Mowel WK, Brewer JR, Kaffe E, Williams KJ, Kluger Y, Smale ST, Crawford JM, Bensinger SJ, Flavell RA. PMID: 38383790; PMCID: PMC10954550.
View in:
PubMed Mentions:
10 Fields:
Translation:
HumansAnimals
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Hepatic GATA4 regulates cholesterol and triglyceride homeostasis in collaboration with LXRs. Genes Dev. 2022 Nov-Dec 1; 36(21-24):1129-1144.
Bideyan L, López Rodríguez M, Priest C, Kennelly JP, Gao Y, Ferrari A, Rajbhandari P, Feng AC, Tevosian SG, Smale ST, Tontonoz P. PMID: 36522129; PMCID: PMC9851399.
View in:
PubMed Mentions:
1 Fields:
Translation:
Animals
-
Oct4:Sox2 binding is essential for establishing but not maintaining active and silent states of dynamically regulated genes in pluripotent cells. Genes Dev. 2022 10 01; 36(19-20):1079-1095.
Lo JH, Edwards M, Langerman J, Sridharan R, Plath K, Smale ST. PMID: 36418052; PMCID: PMC9744233.
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PubMed Mentions:
6 Fields:
Translation:
AnimalsCells
-
Allogeneic hematopoietic stem cell transplantation: lessons learned by a molecular immunologist/transplant patient. Trends Immunol. 2022 06; 43(6):459-465.
Smale ST. PMID: 35490132.
View in:
PubMed Mentions:
1 Fields:
Translation:
Humans
-
Species-Specific Relationships between DNA and Chromatin Properties of CpG Islands in Embryonic Stem Cells and Differentiated Cells. Stem Cell Reports. 2021 04 13; 16(4):899-912.
Langerman J, Lopez D, Pellegrini M, Smale ST. PMID: 33770494; PMCID: PMC8072027.
View in:
PubMed Mentions:
4 Fields:
Translation:
HumansAnimalsCells
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Interferon-mediated reprogramming of membrane cholesterol to evade bacterial toxins. Nat Immunol. 2020 07; 21(7):746-755.
Zhou QD, Chi X, Lee MS, Hsieh WY, Mkrtchyan JJ, Feng AC, He C, York AG, Bui VL, Kronenberger EB, Ferrari A, Xiao X, Daly AE, Tarling EJ, Damoiseaux R, Scumpia PO, Smale ST, Williams KJ, Tontonoz P, Bensinger SJ. PMID: 32514064; PMCID: PMC7778040.
View in:
PubMed Mentions:
47 Fields:
Translation:
HumansAnimalsCells
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Toll-Like Receptors Induce Signal-Specific Reprogramming of the Macrophage Lipidome. Cell Metab. 2020 07 07; 32(1):128-143.e5.
Hsieh WY, Zhou QD, York AG, Williams KJ, Scumpia PO, Kronenberger EB, Hoi XP, Su B, Chi X, Bui VL, Khialeeva E, Kaplan A, Son YM, Divakaruni AS, Sun J, Smale ST, Flavell RA, Bensinger SJ. PMID: 32516576; PMCID: PMC7891175.
View in:
PubMed Mentions:
57 Fields:
Translation:
AnimalsCells
-
A Future Outlook on Molecular Mechanisms of Immunity. Trends Immunol. 2020 07; 41(7):549-555.
Weinmann AS, Youngblood BA, Smale ST, Brink R, Schatz DG, McHeyzer-Williams M. PMID: 32507312.
View in:
PubMed Mentions: Fields:
Translation:
Humans
-
Single cell analysis reveals immune cell-adipocyte crosstalk regulating the transcription of thermogenic adipocytes. Elife. 2019 10 23; 8.
Rajbhandari P, Arneson D, Hart SK, Ahn IS, Diamante G, Santos LC, Zaghari N, Feng AC, Thomas BJ, Vergnes L, Lee SD, Rajbhandari AK, Reue K, Smale ST, Yang X, Tontonoz P. PMID: 31644425; PMCID: PMC6837845.
View in:
PubMed Mentions:
86 Fields:
Translation:
AnimalsCells
-
Dissection of acute stimulus-inducible nucleosome remodeling in mammalian cells. Genes Dev. 2019 09 01; 33(17-18):1159-1174.
Comoglio F, Simonatto M, Polletti S, Liu X, Smale ST, Barozzi I, Natoli G. PMID: 31371436; PMCID: PMC6719622.
View in:
PubMed Mentions:
23 Fields:
Translation:
AnimalsCells
-
Comparison of reprogramming factor targets reveals both species-specific and conserved mechanisms in early iPSC reprogramming. BMC Genomics. 2018 Dec 22; 19(1):956.
Fu K, Chronis C, Soufi A, Bonora G, Edwards M, Smale ST, Zaret KS, Plath K, Pellegrini M. PMID: 30577748; PMCID: PMC6303873.
View in:
PubMed Mentions:
9 Fields:
Translation:
HumansAnimalsCells
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Transcriptional regulation of macrophage cholesterol efflux and atherogenesis by a long noncoding RNA. Nat Med. 2018 03; 24(3):304-312.
Sallam T, Jones M, Thomas BJ, Wu X, Gilliland T, Qian K, Eskin A, Casero D, Zhang Z, Sandhu J, Salisbury D, Rajbhandari P, Civelek M, Hong C, Ito A, Liu X, Daniel B, Lusis AJ, Whitelegge J, Nagy L, Castrillo A, Smale S, Tontonoz P. PMID: 29431742; PMCID: PMC5839972.
View in:
PubMed Mentions:
122 Fields:
Translation:
HumansAnimalsCells
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IL-10 Signaling Remodels Adipose Chromatin Architecture to Limit Thermogenesis and Energy Expenditure. Cell. 2018 01 11; 172(1-2):218-233.e17.
Rajbhandari P, Thomas BJ, Feng AC, Hong C, Wang J, Vergnes L, Sallam T, Wang B, Sandhu J, Seldin MM, Lusis AJ, Fong LG, Katz M, Lee R, Young SG, Reue K, Smale ST, Tontonoz P. PMID: 29249357; PMCID: PMC5766418.
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PubMed Mentions:
96 Fields:
Translation:
AnimalsCells
-
Defined Sensing Mechanisms and Signaling Pathways Contribute to the Global Inflammatory Gene Expression Output Elicited by Ionizing Radiation. Immunity. 2017 09 19; 47(3):421-434.e3.
Purbey PK, Scumpia PO, Kim PJ, Tong AJ, Iwamoto KS, McBride WH, Smale ST. PMID: 28930658; PMCID: PMC5661954.
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PubMed Mentions:
31 Fields:
Translation:
HumansAnimalsCells
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A Macrophage Response to Mycobacterium leprae Phenolic Glycolipid Initiates Nerve Damage in Leprosy. Cell. 2017 Aug 24; 170(5):973-985.e10.
Madigan CA, Cambier CJ, Kelly-Scumpia KM, Scumpia PO, Cheng TY, Zailaa J, Bloom BR, Moody DB, Smale ST, Sagasti A, Modlin RL, Ramakrishnan L. PMID: 28841420; PMCID: PMC5848073.
View in:
PubMed Mentions:
56 Fields:
Translation:
AnimalsCells
-
Opposing roles of Toll-like receptor and cytosolic DNA-STING signaling pathways for Staphylococcus aureus cutaneous host defense. PLoS Pathog. 2017 Jul; 13(7):e1006496.
Scumpia PO, Botten GA, Norman JS, Kelly-Scumpia KM, Spreafico R, Ruccia AR, Purbey PK, Thomas BJ, Modlin RL, Smale ST. PMID: 28704551; PMCID: PMC5526579.
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PubMed Mentions:
38 Fields:
Translation:
HumansAnimalsCells
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Genetic analysis of Ikaros target genes and tumor suppressor function in BCR-ABL1+ pre-B ALL. J Exp Med. 2017 03 06; 214(3):793-814.
Schjerven H, Ayongaba EF, Aghajanirefah A, McLaughlin J, Cheng D, Geng H, Boyd JR, Eggesbø LM, Lindeman I, Heath JL, Park E, Witte ON, Smale ST, Frietze S, Müschen M. PMID: 28190001; PMCID: PMC5339667.
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PubMed Mentions:
19 Fields:
Translation:
HumansAnimalsCells
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The Ly6C(lo)-Down: Targeting Developmental Enhancers for Cell Subset Depletion. Immunity. 2016 11 15; 45(5):949-951.
Thomas BJ, Smale ST. PMID: 27851919.
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PubMed Mentions: Fields:
Translation:
HumansCells
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A Stringent Systems Approach Uncovers Gene-Specific Mechanisms Regulating Inflammation. Cell. 2016 Mar 24; 165(1):165-179.
Tong AJ, Liu X, Thomas BJ, Lissner MM, Baker MR, Senagolage MD, Allred AL, Barish GD, Smale ST. PMID: 26924576; PMCID: PMC4808443.
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PubMed Mentions:
105 Fields:
Translation:
AnimalsCells
-
Type I and Type II Interferon Coordinately Regulate Suppressive Dendritic Cell Fate and Function during Viral Persistence. PLoS Pathog. 2016 Jan; 12(1):e1005356.
Cunningham CR, Champhekar A, Tullius MV, Dillon BJ, Zhen A, de la Fuente JR, Herskovitz J, Elsaesser H, Snell LM, Wilson EB, de la Torre JC, Kitchen SG, Horwitz MA, Bensinger SJ, Smale ST, Brooks DG. PMID: 26808628; PMCID: PMC4726812.
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PubMed Mentions:
41 Fields:
Translation:
AnimalsCells
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Regulation of gene expression dynamics during developmental transitions by the Ikaros transcription factor. Genes Dev. 2015 Sep 01; 29(17):1801-16.
Arenzana TL, Schjerven H, Smale ST. PMID: 26314708; PMCID: PMC4573854.
View in:
PubMed Mentions:
17 Fields:
Translation:
AnimalsCells
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Age-Related Gene Expression Differences in Monocytes from Human Neonates, Young Adults, and Older Adults. PLoS One. 2015; 10(7):e0132061.
Lissner MM, Thomas BJ, Wee K, Tong AJ, Kollmann TR, Smale ST. PMID: 26147648; PMCID: PMC4493075.
View in:
PubMed Mentions:
25 Fields:
Translation:
HumansCells
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Transcriptional control of inflammatory responses. Cold Spring Harb Perspect Biol. 2014 Sep 11; 6(11):a016261.
Smale ST, Natoli G. PMID: 25213094; PMCID: PMC4413233.
View in:
PubMed Mentions:
65 Fields:
Translation:
Cells
-
Restriction of IL-22-producing T cell responses and differential regulation of regulatory T cell compartments by zinc finger transcription factor Ikaros. J Immunol. 2014 Oct 15; 193(8):3934-46.
Heller JJ, Schjerven H, Li S, Lee A, Qiu J, Chen ZM, Smale ST, Zhou L. PMID: 25194055; PMCID: PMC4185244.
View in:
PubMed Mentions:
15 Fields:
Translation:
AnimalsCells
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Toward an understanding of the gene-specific and global logic of inducible gene transcription. Cold Spring Harb Symp Quant Biol. 2013; 78:61-8.
Smale ST, Plevy SE, Weinmann AS, Zhou L, Ramirez-Carrozzi VR, Pope SD, Bhatt DM, Tong AJ. PMID: 24747344.
View in:
PubMed Mentions:
4 Fields:
Translation:
HumansAnimalsCells
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Transcriptional regulation in the immune system: a status report. Trends Immunol. 2014 May; 35(5):190-4.
Smale ST. PMID: 24703179; PMCID: PMC4041609.
View in:
PubMed Mentions:
14 Fields:
Translation:
HumansCells
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Pten null prostate epithelium promotes localized myeloid-derived suppressor cell expansion and immune suppression during tumor initiation and progression. Mol Cell Biol. 2014 Jun; 34(11):2017-28.
Garcia AJ, Ruscetti M, Arenzana TL, Tran LM, Bianci-Frias D, Sybert E, Priceman SJ, Wu L, Nelson PS, Smale ST, Wu H. PMID: 24662052; PMCID: PMC4019050.
View in:
PubMed Mentions:
80 Fields:
Translation:
AnimalsCells
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Chromatin contributions to the regulation of innate immunity. Annu Rev Immunol. 2014; 32:489-511.
Smale ST, Tarakhovsky A, Natoli G. PMID: 24555473.
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PubMed Mentions:
92 Fields:
Translation:
HumansAnimalsCells
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Selective regulation of lymphopoiesis and leukemogenesis by individual zinc fingers of Ikaros. Nat Immunol. 2013 Oct; 14(10):1073-83.
Schjerven H, McLaughlin J, Arenzana TL, Frietze S, Cheng D, Wadsworth SE, Lawson GW, Bensinger SJ, Farnham PJ, Witte ON, Smale ST. PMID: 24013668; PMCID: PMC3800053.
View in:
PubMed Mentions:
69 Fields:
Translation:
AnimalsCells
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Splicing kinetics and transcript release from the chromatin compartment limit the rate of Lipid A-induced gene expression. RNA. 2013 Jun; 19(6):811-27.
Pandya-Jones A, Bhatt DM, Lin CH, Tong AJ, Smale ST, Black DL. PMID: 23616639; PMCID: PMC3683915.
View in:
PubMed Mentions:
66 Fields:
Translation:
AnimalsCells
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Genome-wide identification of Ikaros targets elucidates its contribution to mouse B-cell lineage specification and pre-B-cell differentiation. Blood. 2013 Mar 07; 121(10):1769-82.
Ferreirós-Vidal I, Carroll T, Taylor B, Terry A, Liang Z, Bruno L, Dharmalingam G, Khadayate S, Cobb BS, Smale ST, Spivakov M, Srivastava P, Petretto E, Fisher AG, Merkenschlager M. PMID: 23303821.
View in:
PubMed Mentions:
72 Fields:
Translation:
AnimalsCells
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Designing an enhancer landscape. Cell. 2012 Nov 21; 151(5):929-31.
Xu J, Smale ST. PMID: 23178114; PMCID: PMC3732118.
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PubMed Mentions:
8 Fields:
-
Restraint of inflammatory signaling by interdependent strata of negative regulatory pathways. Nat Immunol. 2012 Oct; 13(10):916-24.
Murray PJ, Smale ST. PMID: 22990889; PMCID: PMC4893774.
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PubMed Mentions:
88 Fields:
Translation:
HumansAnimalsCells
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Transcript dynamics of proinflammatory genes revealed by sequence analysis of subcellular RNA fractions. Cell. 2012 Jul 20; 150(2):279-90.
Bhatt DM, Pandya-Jones A, Tong AJ, Barozzi I, Lissner MM, Natoli G, Black DL, Smale ST. PMID: 22817891; PMCID: PMC3405548.
View in:
PubMed Mentions:
265 Fields:
Translation:
AnimalsCells
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Cross-interference of RLR and TLR signaling pathways modulates antibacterial T cell responses. Nat Immunol. 2012 May 20; 13(7):659-66.
Negishi H, Yanai H, Nakajima A, Koshiba R, Atarashi K, Matsuda A, Matsuki K, Miki S, Doi T, Aderem A, Nishio J, Smale ST, Honda K, Taniguchi T. PMID: 22610141.
View in:
PubMed Mentions:
78 Fields:
Translation:
AnimalsCells
-
Dimer-specific regulatory mechanisms within the NF-κB family of transcription factors. Immunol Rev. 2012 Mar; 246(1):193-204.
Smale ST. PMID: 22435556.
View in:
PubMed Mentions:
98 Fields:
Translation:
HumansAnimalsCells
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Transcriptional regulation in the innate immune system. Curr Opin Immunol. 2012 Feb; 24(1):51-7.
Smale ST. PMID: 22230561; PMCID: PMC3288296.
View in:
PubMed Mentions:
49 Fields:
Translation:
HumansAnimalsCells
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Principles of dimer-specific gene regulation revealed by a comprehensive characterization of NF-κB family DNA binding. Nat Immunol. 2011 Nov 20; 13(1):95-102.
Siggers T, Chang AB, Teixeira A, Wong D, Williams KJ, Ahmed B, Ragoussis J, Udalova IA, Smale ST, Bulyk ML. PMID: 22101729; PMCID: PMC3242931.
View in:
PubMed Mentions:
125 Fields:
-
Hierarchies of NF-κB target-gene regulation. Nat Immunol. 2011 Jul 19; 12(8):689-94.
Smale ST. PMID: 21772277; PMCID: PMC3169328.
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PubMed Mentions:
137 Fields:
Translation:
HumansAnimalsCells
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A distal enhancer in Il12b is the target of transcriptional repression by the STAT3 pathway and requires the basic leucine zipper (B-ZIP) protein NFIL3. J Biol Chem. 2011 Jul 01; 286(26):23582-90.
Smith AM, Qualls JE, O'Brien K, Balouzian L, Johnson PF, Schultz-Cherry S, Smale ST, Murray PJ. PMID: 21566115; PMCID: PMC3123121.
View in:
PubMed Mentions:
39 Fields:
Translation:
AnimalsCells
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NFIL3 is a regulator of IL-12 p40 in macrophages and mucosal immunity. J Immunol. 2011 Apr 15; 186(8):4649-55.
Kobayashi T, Matsuoka K, Sheikh SZ, Elloumi HZ, Kamada N, Hisamatsu T, Hansen JJ, Doty KR, Pope SD, Smale ST, Hibi T, Rothman PB, Kashiwada M, Plevy SE. PMID: 21383239; PMCID: PMC3172700.
View in:
PubMed Mentions:
56 Fields:
Translation:
HumansAnimalsCells
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Immune inhibitory ligand CD200 induction by TLRs and NLRs limits macrophage activation to protect the host from meningococcal septicemia. Cell Host Microbe. 2010 Sep 16; 8(3):236-47.
Mukhopadhyay S, Plüddemann A, Hoe JC, Williams KJ, Varin A, Makepeace K, Aknin ML, Bowdish DM, Smale ST, Barclay AN, Gordon S. PMID: 20833375.
View in:
PubMed Mentions:
40 Fields:
Translation:
HumansAnimalsCells
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Pioneer factors in embryonic stem cells and differentiation. Curr Opin Genet Dev. 2010 Oct; 20(5):519-26.
Smale ST. PMID: 20638836; PMCID: PMC2943026.
View in:
PubMed Mentions:
42 Fields:
Translation:
AnimalsCells
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Seq-ing LPS-induced enhancers. Immunity. 2010 Mar 26; 32(3):296-8.
Smale ST. PMID: 20346768.
View in:
PubMed Mentions:
6 Fields:
Translation:
HumansAnimalsCells
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Selective transcription in response to an inflammatory stimulus. Cell. 2010 Mar 19; 140(6):833-44.
Smale ST. PMID: 20303874; PMCID: PMC2847629.
View in:
PubMed Mentions:
172 Fields:
Translation:
HumansAnimalsCells
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Transcriptional competence and the active marking of tissue-specific enhancers by defined transcription factors in embryonic and induced pluripotent stem cells. Genes Dev. 2009 Dec 15; 23(24):2824-38.
Xu J, Watts JA, Pope SD, Gadue P, Kamps M, Plath K, Zaret KS, Smale ST. PMID: 20008934; PMCID: PMC2800090.
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PubMed Mentions:
102 Fields:
Translation:
AnimalsCells
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Self-renewal of the long-term reconstituting subset of hematopoietic stem cells is regulated by Ikaros. Stem Cells. 2009 Dec; 27(12):3082-92.
Papathanasiou P, Attema JL, Karsunky H, Hosen N, Sontani Y, Hoyne GF, Tunningley R, Smale ST, Weissman IL. PMID: 19816952; PMCID: PMC3401049.
View in:
PubMed Mentions:
22 Fields:
Translation:
AnimalsCells
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Selectivity of the NF-{kappa}B response. Cold Spring Harb Perspect Biol. 2010 Apr; 2(4):a000257.
Sen R, Smale ST. PMID: 20452937; PMCID: PMC2845200.
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PubMed Mentions:
72 Fields:
Translation:
Animals
-
Evaluation of the long-term reconstituting subset of hematopoietic stem cells with CD150. Stem Cells. 2009 Oct; 27(10):2498-508.
Papathanasiou P, Attema JL, Karsunky H, Xu J, Smale ST, Weissman IL. PMID: 19593793; PMCID: PMC2783507.
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PubMed Mentions:
25 Fields:
Translation:
AnimalsCells
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A unifying model for the selective regulation of inducible transcription by CpG islands and nucleosome remodeling. Cell. 2009 Jul 10; 138(1):114-28.
Ramirez-Carrozzi VR, Braas D, Bhatt DM, Cheng CS, Hong C, Doty KR, Black JC, Hoffmann A, Carey M, Smale ST. PMID: 19596239; PMCID: PMC2712736.
View in:
PubMed Mentions:
319 Fields:
Translation:
HumansAnimalsCells
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Regulation of B cell fate commitment and immunoglobulin heavy-chain gene rearrangements by Ikaros. Nat Immunol. 2008 Aug; 9(8):927-36.
Reynaud D, Demarco IA, Reddy KL, Schjerven H, Bertolino E, Chen Z, Smale ST, Winandy S, Singh H. PMID: 18568028; PMCID: PMC2699484.
View in:
PubMed Mentions:
145 Fields:
Translation:
AnimalsCells
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Class-specific regulation of pro-inflammatory genes by MyD88 pathways and IkappaBzeta. J Biol Chem. 2008 May 02; 283(18):12468-77.
Kayama H, Ramirez-Carrozzi VR, Yamamoto M, Mizutani T, Kuwata H, Iba H, Matsumoto M, Honda K, Smale ST, Takeda K. PMID: 18319258.
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PubMed Mentions:
47 Fields:
Translation:
AnimalsCells
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Predominant interaction of both Ikaros and Helios with the NuRD complex in immature thymocytes. J Biol Chem. 2007 Oct 12; 282(41):30227-38.
Sridharan R, Smale ST. PMID: 17681952.
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PubMed Mentions:
83 Fields:
Translation:
HumansAnimalsCells
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Pioneer factor interactions and unmethylated CpG dinucleotides mark silent tissue-specific enhancers in embryonic stem cells. Proc Natl Acad Sci U S A. 2007 Jul 24; 104(30):12377-82.
Xu J, Pope SD, Jazirehi AR, Attema JL, Papathanasiou P, Watts JA, Zaret KS, Weissman IL, Smale ST. PMID: 17640912; PMCID: PMC1941477.
View in:
PubMed Mentions:
66 Fields:
Translation:
HumansAnimalsCells
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Epigenetic characterization of hematopoietic stem cell differentiation using miniChIP and bisulfite sequencing analysis. Proc Natl Acad Sci U S A. 2007 Jul 24; 104(30):12371-6.
Attema JL, Papathanasiou P, Forsberg EC, Xu J, Smale ST, Weissman IL. PMID: 17640913; PMCID: PMC1924790.
View in:
PubMed Mentions:
67 Fields:
Translation:
Cells
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Ikaros DNA-binding proteins as integral components of B cell developmental-stage-specific regulatory circuits. Immunity. 2007 Mar; 26(3):335-44.
Thompson EC, Cobb BS, Sabbattini P, Meixlsperger S, Parelho V, Liberg D, Taylor B, Dillon N, Georgopoulos K, Jumaa H, Smale ST, Fisher AG, Merkenschlager M. PMID: 17363301.
View in:
PubMed Mentions:
91 Fields:
Translation:
AnimalsCells
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An inducible enhancer required for Il12b promoter activity in an insulated chromatin environment. Mol Cell Biol. 2007 Apr; 27(7):2698-712.
Zhou L, Nazarian AA, Xu J, Tantin D, Corcoran LM, Smale ST. PMID: 17242186; PMCID: PMC1899891.
View in:
PubMed Mentions:
31 Fields:
Translation:
AnimalsCells
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A role for Dicer in immune regulation. J Exp Med. 2006 Oct 30; 203(11):2519-27.
Cobb BS, Hertweck A, Smith J, O'Connor E, Graf D, Cook T, Smale ST, Sakaguchi S, Livesey FJ, Fisher AG, Merkenschlager M. PMID: 17060477; PMCID: PMC2118134.
View in:
PubMed Mentions:
277 Fields:
Translation:
AnimalsCells
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Pursuing gene regulation 'logic' via RNA interference and chromatin immunoprecipitation. Nat Immunol. 2006 Jul; 7(7):692-7.
Li CC, Ramirez-Carrozzi VR, Smale ST. PMID: 16785883.
View in:
PubMed Mentions:
3 Fields:
Translation:
HumansAnimalsCells
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Hematopoiesis flies high with Ikaros. Nat Immunol. 2006 Apr; 7(4):367-9.
Smale ST, Dorshkind K. PMID: 16550201.
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PubMed Mentions:
2 Fields:
Translation:
AnimalsCells
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Selective and antagonistic functions of SWI/SNF and Mi-2beta nucleosome remodeling complexes during an inflammatory response. Genes Dev. 2006 Feb 01; 20(3):282-96.
Ramirez-Carrozzi VR, Nazarian AA, Li CC, Gore SL, Sridharan R, Imbalzano AN, Smale ST. PMID: 16452502; PMCID: PMC1361700.
View in:
PubMed Mentions:
224 Fields:
Translation:
AnimalsCells
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A c-Rel subdomain responsible for enhanced DNA-binding affinity and selective gene activation. Genes Dev. 2005 Sep 15; 19(18):2138-51.
Sanjabi S, Williams KJ, Saccani S, Zhou L, Hoffmann A, Ghosh G, Gerondakis S, Natoli G, Smale ST. PMID: 16166378; PMCID: PMC1221885.
View in:
PubMed Mentions:
66 Fields:
Translation:
AnimalsCells
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Transgenic expression of Helios in B lineage cells alters B cell properties and promotes lymphomagenesis. J Immunol. 2005 Sep 15; 175(6):3508-15.
Dovat S, Montecino-Rodriguez E, Schuman V, Teitell MA, Dorshkind K, Smale ST. PMID: 16148093.
View in:
PubMed Mentions:
19 Fields:
Translation:
AnimalsCells
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T cell lineage choice and differentiation in the absence of the RNase III enzyme Dicer. J Exp Med. 2005 May 02; 201(9):1367-73.
Cobb BS, Nesterova TB, Thompson E, Hertweck A, O'Connor E, Godwin J, Wilson CB, Brockdorff N, Fisher AG, Smale ST, Merkenschlager M. PMID: 15867090; PMCID: PMC2213187.
View in:
PubMed Mentions:
258 Fields:
Translation:
AnimalsCells
-
Assembly of silent chromatin during thymocyte development. Semin Immunol. 2005 Apr; 17(2):129-40.
Su RC, Sridharan R, Smale ST. PMID: 15737574.
View in:
PubMed Mentions:
14 Fields:
Translation:
AnimalsCells
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Dynamic assembly of silent chromatin during thymocyte maturation. Nat Genet. 2004 May; 36(5):502-6.
Su RC, Brown KE, Saaber S, Fisher AG, Merkenschlager M, Smale ST. PMID: 15098035.
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PubMed Mentions:
59 Fields:
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AnimalsCells
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Interleukin-10 inhibits interleukin-12 p40 gene transcription by targeting a late event in the activation pathway. Mol Cell Biol. 2004 Mar; 24(6):2385-96.
Zhou L, Nazarian AA, Smale ST. PMID: 14993278; PMCID: PMC355839.
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PubMed Mentions:
42 Fields:
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AnimalsCells
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Ikaros family members from the agnathan Myxine glutinosa and the urochordate Oikopleura dioica: emergence of an essential transcription factor for adaptive immunity. J Immunol. 2003 Dec 01; 171(11):6006-13.
Cupit PM, Hansen JD, McCarty AS, White G, Chioda M, Spada F, Smale ST, Cunningham C. PMID: 14634112.
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PubMed Mentions:
7 Fields:
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HumansAnimalsCells
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Upstream of Ikaros. Trends Immunol. 2003 Nov; 24(11):567-70.
Liberg D, Smale ST, Merkenschlager M. PMID: 14596876.
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PubMed Mentions:
12 Fields:
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AnimalsCells
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C/EBPbeta regulation in lipopolysaccharide-stimulated macrophages. Mol Cell Biol. 2003 Jul; 23(14):4841-58.
Bradley MN, Zhou L, Smale ST. PMID: 12832471; PMCID: PMC162211.
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PubMed Mentions:
57 Fields:
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HumansAnimalsCells
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The establishment and maintenance of lymphocyte identity through gene silencing. Nat Immunol. 2003 Jul; 4(7):607-15.
Smale ST. PMID: 12830135.
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PubMed Mentions:
23 Fields:
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HumansAnimalsCells
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Widespread failure of hematolymphoid differentiation caused by a recessive niche-filling allele of the Ikaros transcription factor. Immunity. 2003 Jul; 19(1):131-44.
Papathanasiou P, Perkins AC, Cobb BS, Ferrini R, Sridharan R, Hoyne GF, Nelms KA, Smale ST, Goodnow CC. PMID: 12871645.
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PubMed Mentions:
57 Fields:
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AnimalsCells
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A Th2 cytokine LCR. Adding a new piece to the regulatory puzzle. Immunity. 2003 Jul; 19(1):1-2.
Smale ST. PMID: 12871632.
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AnimalsCells
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Common interaction surfaces of the toll-like receptor 4 cytoplasmic domain stimulate multiple nuclear targets. Mol Cell Biol. 2003 Apr; 23(7):2543-55.
Ronni T, Agarwal V, Haykinson M, Haberland ME, Cheng G, Smale ST. PMID: 12640135; PMCID: PMC150739.
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PubMed Mentions:
26 Fields:
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HumansAnimalsCells
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The RNA polymerase II core promoter. Annu Rev Biochem. 2003; 72:449-79.
Smale ST, Kadonaga JT. PMID: 12651739.
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PubMed Mentions:
461 Fields:
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HumansAnimalsCells
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Selective dimerization of a C2H2 zinc finger subfamily. Mol Cell. 2003 Feb; 11(2):459-70.
McCarty AS, Kleiger G, Eisenberg D, Smale ST. PMID: 12620233.
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PubMed Mentions:
44 Fields:
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HumansAnimalsCells
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A common mechanism for mitotic inactivation of C2H2 zinc finger DNA-binding domains. Genes Dev. 2002 Dec 01; 16(23):2985-90.
Dovat S, Ronni T, Russell D, Ferrini R, Cobb BS, Smale ST. PMID: 12464629; PMCID: PMC187490.
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PubMed Mentions:
62 Fields:
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AnimalsCells
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Chromatin structure and gene regulation in the immune system. Annu Rev Immunol. 2002; 20:427-62.
Smale ST, Fisher AG. PMID: 11861609.
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PubMed Mentions:
53 Fields:
Translation:
HumansAnimalsCells