Julian Philip Whitelegge

Title(s)Adjunct Professor, Psychiatry and Biobehavioral Sciences
SchoolMedicine
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    Collapse Research 
    Collapse Research Activities and Funding
    Microfluidics for High-Throughput HDX-MS
    NIH R21GM104593Aug 20, 2012 - May 31, 2016
    Role: Principal Investigator
    Organ-specific NRF2-mediated protein signatures of radiation exposure & tissue da
    NIH R01AI101888May 15, 2012 - Apr 30, 2018
    Role: Principal Investigator
    Peptide Biomarkers of drug exposure: from brain microdialysate to plasma
    NIH R21DA027499Sep 1, 2009 - Aug 31, 2012
    Role: Co-Principal Investigator
    Proteomic Approaches to Protein Fatty Acylation
    NIH R21RR023132Aug 15, 2009 - Jul 31, 2012
    Role: Principal Investigator
    Subtle Modification of Isotope Ratio Proteomics (SMIRP)
    NIH R21RR021913Mar 22, 2008 - Feb 28, 2012
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Integrated Multiomics Analysis of Salivary Exosomes to Identify Biomarkers Associated with Changes in Mood States and Fatigue. Int J Mol Sci. 2022 May 09; 23(9). Cohn W, Zhu C, Campagna J, Bilousova T, Spilman P, Teter B, Li F, Guo R, Elashoff D, Cole GM, Avidan A, Faull KF, Whitelegge J, Wong DTW, John V. PMID: 35563647; PMCID: PMC9105576.
      View in: PubMed   Mentions:    Fields:    Translation:Cells
    2. Mass spectrometry analysis of the photosystem II assembly factor Psb27 revealed variations in its lipid modification. Photosynth Res. 2021 Dec 15. Lambertz J, Liauw P, Whitelegge JP, Nowaczyk MM. PMID: 34910272.
      View in: PubMed   Mentions: 1     Fields:    
    3. Mapping Proximity Associations of Core Spindle Assembly Checkpoint Proteins. J Proteome Res. 2021 07 02; 20(7):3414-3427. Garcia YA, Velasquez EF, Gao LW, Gholkar AA, Clutario KM, Cheung K, Williams-Hamilton T, Whitelegge JP, Torres JZ. PMID: 34087075; PMCID: PMC8256817.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCells
    4. Classes of Drugs that Mitigate Radiation Syndromes. Front Pharmacol. 2021; 12:666776. Micewicz ED, Damoiseaux RD, Deng G, Gomez A, Iwamoto KS, Jung ME, Nguyen C, Norris AJ, Ratikan JA, Ruchala P, Sayre JW, Schaue D, Whitelegge JP, McBride WH. PMID: 34084139; PMCID: PMC8167044.
      View in: PubMed   Mentions:
    5. Dissociation Strategies to Maximize Coverage of α-Helical Domains in Top-Down Mass Spectrometry of Integral Membrane Proteins. J Am Soc Mass Spectrom. 2021 Jun 02; 32(6):1380-1387. Cohn W, Huguet R, Zabrouskov V, Whitelegge J. PMID: 33956438.
      View in: PubMed   Mentions: 1     Fields:    Translation:Cells
    6. DUSP7 regulates the activity of ERK2 to promote proper chromosome alignment during cell division. J Biol Chem. 2021 Jan-Jun; 296:100676. Guo X, Ramirez I, Garcia YA, Velasquez EF, Gholkar AA, Cohn W, Whitelegge JP, Tofig B, Damoiseaux R, Torres JZ. PMID: 33865857; PMCID: PMC8131738.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    7. The Photosystem II Assembly Factor Ycf48 from the Cyanobacterium Synechocystis sp. PCC 6803 Is Lipidated Using an Atypical Lipobox Sequence. Int J Mol Sci. 2021 Apr 02; 22(7). Knoppová J, Yu J, Janouškovec J, Halada P, Nixon PJ, Whitelegge JP, Komenda J. PMID: 33918522; PMCID: PMC8038367.
      View in: PubMed   Mentions: 5     Fields:    Translation:Cells
    8. A Novel SOD1 Intermediate Oligomer, Role of Free Thiols and Disulfide Exchange. Front Neurosci. 2020; 14:619279. Koo BK, Munroe W, Gralla EB, Valentine JS, Whitelegge JP. PMID: 33679289; PMCID: PMC7930385.
      View in: PubMed   Mentions: 1  
    9. Naked Mole-Rat, a Rodent with an Apolipoprotein A-I Dimer. Lipids. 2021 05; 56(3):269-278. Puppione DL, Tran DP, Zenaidee MA, Charugundla S, Whitelegge JP, Buffenstein R. PMID: 33336429.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    10. First sequencing of ancient coral skeletal proteins. Sci Rep. 2020 11 10; 10(1):19407. Drake JL, Whitelegge JP, Jacobs DK. PMID: 33173075; PMCID: PMC7655939.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    11. Age-induced mitochondrial DNA point mutations are inadequate to alter metabolic homeostasis in response to nutrient challenge. Aging Cell. 2020 11; 19(11):e13166. Moore TM, Zhou Z, Strumwasser AR, Cohn W, Lin AJ, Cory K, Whitney K, Ho T, Ho T, Lee JL, Rucker DH, Hoang AN, Widjaja K, Abrishami AD, Charugundla S, Stiles L, Whitelegge JP, Turcotte LP, Wanagat J, Hevener AL. PMID: 33049094; PMCID: PMC7681042.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    12. A novel chloroplast super-complex consisting of the ATP synthase and photosystem I reaction center. PLoS One. 2020; 15(8):e0237569. Bhaduri S, Singh SK, Cohn W, Hasan SS, Whitelegge JP, Cramer WA. PMID: 32817667; PMCID: PMC7444523.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    13. Regulation of Iron Homeostasis through Parkin-Mediated Lactoferrin Ubiquitylation. Biochemistry. 2020 08 18; 59(32):2916-2921. Gholkar AA, Schmollinger S, Velasquez EF, Lo YC, Cohn W, Capri J, Dharmarajan H, Deardorff WJ, Gao LW, Abdusamad M, Whitelegge JP, Torres JZ. PMID: 32786404; PMCID: PMC7803182.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    14. Type V Collagen in Scar Tissue Regulates the Size of Scar after Heart Injury. Cell. 2020 08 06; 182(3):545-562.e23. Yokota T, McCourt J, Ma F, Ren S, Li S, Kim TH, Kurmangaliyev YZ, Nasiri R, Ahadian S, Nguyen T, Tan XHM, Zhou Y, Wu R, Rodriguez A, Cohn W, Wang Y, Whitelegge J, Ryazantsev S, Khademhosseini A, Teitell MA, Chiou PY, Birk DE, Rowat AC, Crosbie RH, Pellegrini M, Seldin M, Lusis AJ, Deb A. PMID: 32621799; PMCID: PMC7415659.
      View in: PubMed   Mentions: 31     Fields:    Translation:AnimalsCells
    15. Plasmin-mediated proteolysis of human factor IXa in the presence of calcium/phospholipid: Conversion of procoagulant factor IXa to a fibrinolytic enhancer. J Thromb Haemost. 2020 05; 18(5):1171-1182. Schmidt AE, Vadivel K, Whitelegge J, Bajaj SP. PMID: 32073726; PMCID: PMC7363452.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    16. Helicobacter pylori infection impairs chaperone-assisted maturation of Na-K-ATPase in gastric epithelium. Am J Physiol Gastrointest Liver Physiol. 2020 05 01; 318(5):G931-G945. Marcus EA, Tokhtaeva E, Jimenez JL, Wen Y, Naini BV, Heard AN, Kim S, Capri J, Cohn W, Whitelegge JP, Vagin O. PMID: 32174134; PMCID: PMC7272721.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
    17. Targeting a Subset of the Membrane Proteome for Top-Down Mass Spectrometry: Introducing the Proteolipidome. Proteomes. 2020 Mar 10; 8(1). Whitelegge J. PMID: 32164246; PMCID: PMC7151669.
      View in: PubMed   Mentions: 1  
    18. Physiological and evolutionary implications of tetrameric photosystem I in cyanobacteria. Nat Plants. 2019 12; 5(12):1309-1319. Li M, Calteau A, Semchonok DA, Witt TA, Nguyen JT, Sassoon N, Boekema EJ, Whitelegge J, Gugger M, Bruce BD. PMID: 31819227.
      View in: PubMed   Mentions: 12     Fields:    Translation:Cells
    19. Extracellular Vesicles From Auditory Cells as Nanocarriers for Anti-inflammatory Drugs and Pro-resolving Mediators. Front Cell Neurosci. 2019; 13:530. Kalinec GM, Gao L, Cohn W, Whitelegge JP, Faull KF, Kalinec F. PMID: 31849615; PMCID: PMC6895008.
      View in: PubMed   Mentions: 11  
    20. Diminished viability of human ovarian cancer cells by antigen-specific delivery of carbon monoxide with a family of photoactivatable antibody-photoCORM conjugates. Chem Sci. 2020 Jan 14; 11(2):467-473. Kawahara B, Gao L, Cohn W, Whitelegge JP, Sen S, Janzen C, Mascharak PK. PMID: 32190266; PMCID: PMC7067254.
      View in: PubMed   Mentions: 5  
    21. Quantitative Proteomics Using Formalin-fixed, Paraffin-embedded Biopsy Tissues in Inflammatory Disease. J Proteomics Bioinform. 2019; 12(7):104-112. Amarnani A, Capri JR, Souda P, Elashoff DA, Lopez IA, Whitelegge JP, Singh RR. PMID: 32431480; PMCID: PMC7236785.
      View in: PubMed   Mentions: 3  
    22. Time-Dependent Measurement of Nrf2-Regulated Antioxidant Response to Ionizing Radiation Toward Identifying Potential Protein Biomarkers for Acute Radiation Injury. Proteomics Clin Appl. 2019 11; 13(6):e1900035. Liu K, Singer E, Cohn W, Micewicz ED, McBride WH, Whitelegge JP, Loo JA. PMID: 31419066; PMCID: PMC7213060.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsPHPublic Health
    23. Enhanced mitochondrial inhibition by 3,4-dihydroxyphenyl-acetaldehyde (DOPAL)-oligomerized α-synuclein. J Neurosci Res. 2019 12; 97(12):1689-1705. Sarafian TA, Yacoub A, Kunz A, Aranki B, Serobyan G, Cohn W, Whitelegge JP, Watson JB. PMID: 31420910; PMCID: PMC6801072.
      View in: PubMed   Mentions: 5     Fields:    Translation:AnimalsCells
    24. PTPσ inhibitors promote hematopoietic stem cell regeneration. Nat Commun. 2019 08 14; 10(1):3667. Zhang Y, Roos M, Himburg H, Termini CM, Quarmyne M, Li M, Zhao L, Kan J, Fang T, Yan X, Pohl K, Diers E, Jin Gim H, Damoiseaux R, Whitelegge J, McBride W, Jung ME, Chute JP. PMID: 31413255; PMCID: PMC6694155.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansAnimalsCells
    25. Best practices and benchmarks for intact protein analysis for top-down mass spectrometry. Nat Methods. 2019 07; 16(7):587-594. Donnelly DP, Rawlins CM, DeHart CJ, Fornelli L, Schachner LF, Lin Z, Lippens JL, Aluri KC, Sarin R, Chen B, Lantz C, Jung W, Johnson KR, Koller A, Wolff JJ, Campuzano IDG, Auclair JR, Ivanov AR, Whitelegge JP, Paša-Tolic L, Chamot-Rooke J, Danis PO, Smith LM, Tsybin YO, Loo JA, Ge Y, Kelleher NL, Agar JN. PMID: 31249407; PMCID: PMC6719561.
      View in: PubMed   Mentions: 66     Fields:    Translation:Cells
    26. Multiple neurosteroid and cholesterol binding sites in voltage-dependent anion channel-1 determined by photo-affinity labeling. Biochim Biophys Acta Mol Cell Biol Lipids. 2019 10; 1864(10):1269-1279. Cheng WWL, Budelier MM, Sugasawa Y, Bergdoll L, Queralt-Martín M, Rosencrans W, Rostovtseva TK, Chen ZW, Abramson J, Krishnan K, Covey DF, Whitelegge JP, Evers AS. PMID: 31176038; PMCID: PMC6681461.
      View in: PubMed   Mentions: 10     Fields:    Translation:AnimalsCells
    27. Preliminary Characterization of Extracellular Vesicles From Auditory HEI-OC1 Cells. Ann Otol Rhinol Laryngol. 2019 06; 128(6_suppl):52S-60S. Kalinec GM, Cohn W, Whitelegge JP, Faull KF, Kalinec F. PMID: 31092033.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    28. Phenotypic and proteomic characterization of treponemes associated with bovine digital dermatitis. Vet Microbiol. 2019 Aug; 235:35-42. Nally JE, Hornsby RL, Alt DP, Whitelegge JP. PMID: 31282377; PMCID: PMC6684396.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    29. Glucose transporter inhibitor-conjugated insulin mitigates hypoglycemia. Proc Natl Acad Sci U S A. 2019 05 28; 116(22):10744-10748. Wang J, Yu J, Zhang Y, Kahkoska AR, Wang Z, Fang J, Whitelegge JP, Li S, Buse JB, Gu Z. PMID: 31097579; PMCID: PMC6561193.
      View in: PubMed   Mentions: 14     Fields:    Translation:Animals
    30. The Aftermath of Surviving Acute Radiation Hematopoietic Syndrome and its Mitigation. Radiat Res. 2019 04; 191(4):323-334. Micewicz ED, Iwamoto KS, Ratikan JA, Nguyen C, Xie MW, Cheng G, Boxx GM, Deriu E, Damoiseaux RD, Whitelegge JP, Ruchala PP, Avetisyan R, Jung ME, Lawson G, Nemeth E, Ganz T, Sayre JW, McBride WH, Schaue D. PMID: 30730284; PMCID: PMC6482953.
      View in: PubMed   Mentions: 7     Fields:    Translation:AnimalsPHPublic Health
    31. Structural biology workflow for the expression and characterization of functional human sodium glucose transporter type 1 in Pichia pastoris. Sci Rep. 2019 02 04; 9(1):1203. Suades A, Alcaraz A, Cruz E, Álvarez-Marimon E, Whitelegge JP, Manyosa J, Cladera J, Perálvarez-Marín A. PMID: 30718602; PMCID: PMC6362292.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimals
    32. Insights into the structure and molecular topography of the fatty acylated domain of synaptotagmin-1. Biochim Biophys Acta Biomembr. 2019 03 01; 1861(3):677-684. Ruchala P, Waring AJ, Cilluffo M, Whitelegge JP, Gundersen CB. PMID: 30615859.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    33. COI1-dependent jasmonate signalling affects growth, metabolite production and cell wall protein composition in arabidopsis. Ann Bot. 2018 12 31; 122(7):1117-1129. Bömer M, O'Brien JA, Pérez-Salamó I, Krasauskas J, Finch P, Briones A, Daudi A, Souda P, Tsui TL, Whitelegge JP, Paul Bolwell G, Devoto A. PMID: 29924303; PMCID: PMC6324744.
      View in: PubMed   Mentions: 13     Fields:    Translation:AnimalsCells
    34. 1-(4-nitrobenzenesulfonyl)-4-penylpiperazine increases the number of Peyer's patch-associated regenerating crypts in the small intestines after radiation injury. Radiother Oncol. 2019 03; 132:8-15. Bhat K, Duhachek-Muggy S, Ramanathan R, Saki M, Alli C, Medina P, Damoiseaux R, Whitelegge J, McBride WH, Schaue D, Vlashi E, Pajonk F. PMID: 30825974; PMCID: PMC6400303.
      View in: PubMed   Mentions: 6     Fields:    Translation:AnimalsPHPublic Health
    35. The impact of exercise on mitochondrial dynamics and the role of Drp1 in exercise performance and training adaptations in skeletal muscle. Mol Metab. 2019 03; 21:51-67. Moore TM, Zhou Z, Cohn W, Norheim F, Lin AJ, Kalajian N, Strumwasser AR, Cory K, Whitney K, Ho T, Ho T, Lee JL, Rucker DH, Shirihai O, van der Bliek AM, Whitelegge JP, Seldin MM, Lusis AJ, Lee S, Drevon CA, Mahata SK, Turcotte LP, Hevener AL. PMID: 30591411; PMCID: PMC6407367.
      View in: PubMed   Mentions: 37     Fields:    Translation:HumansAnimalsCells
    36. Proteomics of Bronchoalveolar Lavage Fluid Reveals a Lung Oxidative Stress Response in Murine Herpesvirus-68 Infection. Viruses. 2018 11 27; 10(12). Bortz E, Wu TT, Patel P, Whitelegge JP, Sun R. PMID: 30486363; PMCID: PMC6316452.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    37. Exposure of Solvent-Inaccessible Regions in the Amyloidogenic Protein Human SOD1 Determined by Hydroxyl Radical Footprinting. J Am Soc Mass Spectrom. 2019 Feb; 30(2):218-226. Sheng Y, Capri J, Waring A, Valentine JS, Whitelegge J. PMID: 30328005; PMCID: PMC6347482.
      View in: PubMed   Mentions: 3     Fields:    Translation:Cells
    38. Investigation of Anti-SOD1 Antibodies Yields New Structural Insight into SOD1 Misfolding and Surprising Behavior of the Antibodies Themselves. ACS Chem Biol. 2018 09 21; 13(9):2794-2807. Atlasi RS, Malik R, Corrales CI, Tzeplaeff L, Whitelegge JP, Cashman NR, Bitan G. PMID: 30110532; PMCID: PMC6475120.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansAnimalsCells
    39. Properties, metabolism and roles of sulfogalactosylglycerolipid in male reproduction. Prog Lipid Res. 2018 10; 72:18-41. Tanphaichitr N, Kongmanas K, Faull KF, Whitelegge J, Compostella F, Goto-Inoue N, Linton JJ, Doyle B, Oko R, Xu H, Panza L, Saewu A. PMID: 30149090; PMCID: PMC6239905.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansAnimalsCells
    40. Quantitative Measure of Intestinal Permeability Using Blue Food Coloring. J Surg Res. 2019 01; 233:20-25. Angarita SAK, Duarte S, Russell TA, Ruchala P, Elliott IA, Whitelegge JP, Zarrinpar A. PMID: 30502249; PMCID: PMC6561122.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCTClinical Trials
    41. HSP70 Copurifies with Zika Virus Particles. Virology. 2018 09; 522:228-233. Khachatoorian R, Cohn W, Buzzanco A, Riahi R, Arumugaswami V, Dasgupta A, Whitelegge JP, French SW. PMID: 30053656.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimalsCells
    42. Lipid Modulation of Membrane Protein Function. Cell Chem Biol. 2018 07 19; 25(7):803-804. Whitelegge J. PMID: 30028973.
      View in: PubMed   Mentions:    Fields:    Translation:Animals
    43. Amyloid seeding of transthyretin by ex vivo cardiac fibrils and its inhibition. Proc Natl Acad Sci U S A. 2018 07 17; 115(29):E6741-E6750. Saelices L, Chung K, Lee JH, Cohn W, Whitelegge JP, Benson MD, Eisenberg DS. PMID: 29954863; PMCID: PMC6055172.
      View in: PubMed   Mentions: 24     Fields:    Translation:Humans
    44. The S-layer biogenesis system of Synechocystis 6803: Role of Sll1180 and Sll1181 (E. coli HlyB and HlyD analogs) as type-I secretion components for Sll1951 export. Biochim Biophys Acta Biomembr. 2018 Jul; 1860(7):1436-1446. Agarwal R, Whitelegge JP, Saini S, Shrivastav AP. PMID: 29678468.
      View in: PubMed   Mentions: 2     Fields:    Translation:Cells
    45. Transcriptional regulation of macrophage cholesterol efflux and atherogenesis by a long noncoding RNA. Nat Med. 2018 03; 24(3):304-312. Sallam T, Jones M, Thomas BJ, Wu X, Gilliland T, Qian K, Eskin A, Casero D, Zhang Z, Sandhu J, Salisbury D, Rajbhandari P, Civelek M, Hong C, Ito A, Liu X, Daniel B, Lusis AJ, Whitelegge J, Nagy L, Castrillo A, Smale S, Tontonoz P. PMID: 29431742; PMCID: PMC5839972.
      View in: PubMed   Mentions: 90     Fields:    Translation:HumansAnimalsCells
    46. Ethanol Induced Disordering of Pancreatic Acinar Cell Endoplasmic Reticulum: An ER Stress/Defective Unfolded Protein Response Model. Cell Mol Gastroenterol Hepatol. 2018; 5(4):479-497. Waldron RT, Su HY, Piplani H, Capri J, Cohn W, Whitelegge JP, Faull KF, Sakkiah S, Abrol R, Yang W, Zhou B, Freeman MR, Pandol SJ, Lugea A. PMID: 29930975; PMCID: PMC6009017.
      View in: PubMed   Mentions: 10     Fields:    
    47. A protease-resistant Escherichia coli asparaginase with outstanding stability and enhanced anti-leukaemic activity in vitro. Sci Rep. 2017 11 03; 7(1):14479. Maggi M, Mittelman SD, Parmentier JH, Colombo G, Meli M, Whitmire JM, Merrell DS, Whitelegge J, Scotti C. PMID: 29101342; PMCID: PMC5670125.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansCells
    48. Mitochondrial Dysfunction, Through Impaired Autophagy, Leads to Endoplasmic Reticulum Stress, Deregulated Lipid Metabolism, and Pancreatitis in Animal Models. Gastroenterology. 2018 Feb; 154(3):689-703. Biczo G, Vegh ET, Shalbueva N, Mareninova OA, Elperin J, Lotshaw E, Gretler S, Lugea A, Malla SR, Dawson D, Ruchala P, Whitelegge J, French SW, Wen L, Husain SZ, Gorelick FS, Hegyi P, Rakonczay Z, Gukovsky I, Gukovskaya AS. PMID: 29074451; PMCID: PMC6369139.
      View in: PubMed   Mentions: 67     Fields:    Translation:HumansAnimalsCells
    49. Peptide Composition of Stroke Causing Emboli Correlate with Serum Markers of Atherosclerosis and Inflammation. Front Neurol. 2017; 8:427. Rao NM, Capri J, Cohn W, Abdaljaleel M, Restrepo L, Gornbein JA, Yong WH, Liebeskind DS, Whitelegge JP. PMID: 28919876; PMCID: PMC5585134.
      View in: PubMed   Mentions: 14  
    50. ATR inhibition facilitates targeting of leukemia dependence on convergent nucleotide biosynthetic pathways. Nat Commun. 2017 08 14; 8(1):241. Le TM, Poddar S, Capri JR, Abt ER, Kim W, Wei L, Uong NT, Cheng CM, Braas D, Nikanjam M, Rix P, Merkurjev D, Zaretsky J, Kornblum HI, Ribas A, Herschman HR, Whitelegge J, Faull KF, Donahue TR, Czernin J, Radu CG. PMID: 28808226; PMCID: PMC5556071.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansAnimalsCells
    51. Integral membrane proteins: bottom-up, top-down and structural proteomics. Expert Rev Proteomics. 2017 08; 14(8):715-723. Kar UK, Simonian M, Whitelegge JP. PMID: 28737967; PMCID: PMC6310004.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansCells
    52. 4-(Nitrophenylsulfonyl)piperazines mitigate radiation damage to multiple tissues. PLoS One. 2017; 12(7):e0181577. Micewicz ED, Kim K, Iwamoto KS, Ratikan JA, Cheng G, Boxx GM, Damoiseaux RD, Whitelegge JP, Ruchala P, Nguyen C, Purbey P, Loo J, Deng G, Jung ME, Sayre JW, Norris AJ, Schaue D, McBride WH. PMID: 28732024; PMCID: PMC5521796.
      View in: PubMed   Mentions: 7     Fields:    Translation:AnimalsCellsPHPublic Health
    53. Neural Circuit-Specialized Astrocytes: Transcriptomic, Proteomic, Morphological, and Functional Evidence. Neuron. 2017 Aug 02; 95(3):531-549.e9. Chai H, Diaz-Castro B, Shigetomi E, Monte E, Octeau JC, Yu X, Cohn W, Rajendran PS, Vondriska TM, Whitelegge JP, Coppola G, Khakh BS. PMID: 28712653; PMCID: PMC5811312.
      View in: PubMed   Mentions: 236     Fields:    Translation:AnimalsCells
    54. Photoaffinity labeling with cholesterol analogues precisely maps a cholesterol-binding site in voltage-dependent anion channel-1. J Biol Chem. 2017 06 02; 292(22):9294-9304. Budelier MM, Cheng WWL, Bergdoll L, Chen ZW, Janetka JW, Abramson J, Krishnan K, Mydock-McGrane L, Covey DF, Whitelegge JP, Evers AS. PMID: 28396346; PMCID: PMC5454110.
      View in: PubMed   Mentions: 29     Fields:    Translation:AnimalsCells
    55. RNA-binding protein PSPC1 promotes the differentiation-dependent nuclear export of adipocyte RNAs. J Clin Invest. 2017 Mar 01; 127(3):987-1004. Wang J, Rajbhandari P, Damianov A, Han A, Sallam T, Waki H, Villanueva CJ, Lee SD, Nielsen R, Mandrup S, Reue K, Young SG, Whitelegge J, Saez E, Black DL, Tontonoz P. PMID: 28192372; PMCID: PMC5330726.
      View in: PubMed   Mentions: 17     Fields:    Translation:AnimalsCells
    56. Stimulation of synaptoneurosome glutamate release by monomeric and fibrillated α-synuclein. J Neurosci Res. 2017 09; 95(9):1871-1887. Sarafian TA, Littlejohn K, Yuan S, Fernandez C, Cilluffo M, Koo BK, Whitelegge JP, Watson JB. PMID: 28117497; PMCID: PMC5509520.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimalsCells
    57. Full Membrane Protein Coverage Digestion and Quantitative Bottom-Up Mass Spectrometry Proteomics. Methods Mol Biol. 2017; 1550:61-67. Capri J, Whitelegge JP. PMID: 28188523.
      View in: PubMed   Mentions: 6     Fields:    Translation:Cells
    58. Relationship between mutant Cu/Zn superoxide dismutase 1 maturation and inclusion formation in cell models. J Neurochem. 2017 01; 140(1):140-150. Ayers JI, McMahon B, Gill S, Lelie HL, Fromholt S, Brown H, Valentine JS, Whitelegge JP, Borchelt DR. PMID: 27727458; PMCID: PMC5283795.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansAnimalsCells
    59. Trans-membrane Signaling in Photosynthetic State Transitions: REDOX- AND STRUCTURE-DEPENDENT INTERACTION IN VITRO BETWEEN STT7 KINASE AND THE CYTOCHROME b6f COMPLEX. J Biol Chem. 2016 Oct 07; 291(41):21740-21750. Singh SK, Hasan SS, Zakharov SD, Naurin S, Cohn W, Ma J, Whitelegge JP, Cramer WA. PMID: 27539852; PMCID: PMC5076842.
      View in: PubMed   Mentions: 8     Fields:    Translation:AnimalsCells
    60. Feedback modulation of cholesterol metabolism by the lipid-responsive non-coding RNA LeXis. Nature. 2016 06 02; 534(7605):124-8. Sallam T, Jones MC, Gilliland T, Zhang L, Wu X, Eskin A, Sandhu J, Casero D, Vallim TQ, Hong C, Katz M, Lee R, Whitelegge J, Tontonoz P. PMID: 27251289; PMCID: PMC4896091.
      View in: PubMed   Mentions: 102     Fields:    Translation:AnimalsCells
    61. Skeletal muscle action of estrogen receptor α is critical for the maintenance of mitochondrial function and metabolic homeostasis in females. Sci Transl Med. 2016 Apr 13; 8(334):334ra54. Ribas V, Drew BG, Zhou Z, Phun J, Kalajian NY, Soleymani T, Daraei P, Widjaja K, Wanagat J, de Aguiar Vallim TQ, Fluitt AH, Bensinger S, Le T, Radu C, Whitelegge JP, Beaven SW, Tontonoz P, Lusis AJ, Parks BW, Vergnes L, Reue K, Singh H, Bopassa JC, Toro L, Stefani E, Watt MJ, Schenk S, Akerstrom T, Kelly M, Pedersen BK, Hewitt SC, Korach KS, Hevener AL. PMID: 27075628; PMCID: PMC4934679.
      View in: PubMed   Mentions: 91     Fields:    Translation:HumansAnimalsCells
    62. Septin oligomerization regulates persistent expression of ErbB2/HER2 in gastric cancer cells. Biochem J. 2016 06 15; 473(12):1703-18. Marcus EA, Tokhtaeva E, Turdikulova S, Capri J, Whitelegge JP, Scott DR, Sachs G, Berditchevski F, Vagin O. PMID: 27048593; PMCID: PMC4903893.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansCells
    63. Translation Control of Swarming Proficiency in Bacillus subtilis by 5-Amino-pentanolylated Elongation Factor P. J Biol Chem. 2016 May 20; 291(21):10976-85. Rajkovic A, Hummels KR, Witzky A, Erickson S, Gafken PR, Whitelegge JP, Faull KF, Kearns DB, Ibba M. PMID: 27002156; PMCID: PMC4900249.
      View in: PubMed   Mentions: 22     Fields:    Translation:Cells
    64. Proteomic Analysis of the Mammalian Katanin Family of Microtubule-severing Enzymes Defines Katanin p80 subunit B-like 1 (KATNBL1) as a Regulator of Mammalian Katanin Microtubule-severing. Mol Cell Proteomics. 2016 05; 15(5):1658-69. Cheung K, Senese S, Kuang J, Bui N, Ongpipattanakul C, Gholkar A, Cohn W, Capri J, Whitelegge JP, Torres JZ. PMID: 26929214; PMCID: PMC4858946.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansCells
    65. Proteomics Analysis of Brain Meningiomas in Pursuit of Novel Biomarkers of the Aggressive Behavior. J Proteomics Bioinform. 2016; 9(2):53-57. Barkhoudarian G, Whitelegge JP, Kelly DF, Simonian M. PMID: 27019568; PMCID: PMC4807620.
      View in: PubMed   Mentions: 11  
    66. Phospho-Network Analysis Identifies and Quantifies Hepatitis C Virus (HCV)-induced Hepatocellular Carcinoma (HCC) Proteins Regulating Viral-mediated Tumor Growth. Cancer Genomics Proteomics. 2016 09-10; 13(5):339-57. Lu NT, Liu NM, Vu JQ, Patel D, Cohn W, Capri J, Ziegler M, Patel N, Tramontano A, Williams R, Whitelegge J, French SW. PMID: 27566653; PMCID: PMC5070624.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    67. The X-Linked-Intellectual-Disability-Associated Ubiquitin Ligase Mid2 Interacts with Astrin and Regulates Astrin Levels to Promote Cell Division. Cell Rep. 2016 Jan 12; 14(2):180-8. Gholkar AA, Senese S, Lo YC, Vides E, Contreras E, Hodara E, Capri J, Whitelegge JP, Torres JZ. PMID: 26748699; PMCID: PMC4724641.
      View in: PubMed   Mentions: 15     Fields:    Translation:Humans
    68. Ketones block amyloid entry and improve cognition in an Alzheimer's model. Neurobiol Aging. 2016 Mar; 39:25-37. Yin JX, Maalouf M, Han P, Zhao M, Gao M, Dharshaun T, Ryan C, Whitelegge J, Wu J, Eisenberg D, Reiman EM, Schweizer FE, Shi J. PMID: 26923399.
      View in: PubMed   Mentions: 46     Fields:    Translation:AnimalsCells
    69. The Disulfide Bond, but Not Zinc or Dimerization, Controls Initiation and Seeded Growth in Amyotrophic Lateral Sclerosis-linked Cu,Zn Superoxide Dismutase (SOD1) Fibrillation. J Biol Chem. 2015 Dec 18; 290(51):30624-36. Chattopadhyay M, Nwadibia E, Strong CD, Gralla EB, Valentine JS, Whitelegge JP. PMID: 26511321; PMCID: PMC4683282.
      View in: PubMed   Mentions: 28     Fields:    Translation:HumansCells
    70. Uncovering the Mechanism of Aggregation of Human Transthyretin. J Biol Chem. 2015 Nov 27; 290(48):28932-43. Saelices L, Johnson LM, Liang WY, Sawaya MR, Cascio D, Ruchala P, Whitelegge J, Jiang L, Riek R, Eisenberg DS. PMID: 26459562; PMCID: PMC4661406.
      View in: PubMed   Mentions: 52     Fields:    Translation:HumansCells
    71. High CO2 Leads to Na,K-ATPase Endocytosis via c-Jun Amino-Terminal Kinase-Induced LMO7b Phosphorylation. Mol Cell Biol. 2015 Dec; 35(23):3962-73. Dada LA, Trejo Bittar HE, Welch LC, Vagin O, Deiss-Yehiely N, Kelly AM, Baker MR, Capri J, Cohn W, Whitelegge JP, Vadász I, Gruenbaum Y, Sznajder JI. PMID: 26370512; PMCID: PMC4628060.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansAnimalsCells
    72. Structure of the toxic core of α-synuclein from invisible crystals. Nature. 2015 Sep 24; 525(7570):486-90. Rodriguez JA, Ivanova MI, Sawaya MR, Cascio D, Reyes FE, Shi D, Sangwan S, Guenther EL, Johnson LM, Zhang M, Jiang L, Arbing MA, Nannenga BL, Hattne J, Whitelegge J, Brewster AS, Messerschmidt M, Boutet S, Sauter NK, Gonen T, Eisenberg DS. PMID: 26352473; PMCID: PMC4791177.
      View in: PubMed   Mentions: 221     Fields:    Translation:HumansCells
    73. Lipid-conjugated Smac analogues. Bioorg Med Chem Lett. 2015 Oct 15; 25(20):4419-27. Micewicz ED, Ratikan JA, Waring AJ, Whitelegge JP, McBride WH, Ruchala P. PMID: 26384289; PMCID: PMC4592835.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimalsCells
    74. The Structure and Interactions of Periplasmic Domains of Crucial MmpL Membrane Proteins from Mycobacterium tuberculosis. Chem Biol. 2015 Aug 20; 22(8):1098-107. Chim N, Torres R, Liu Y, Capri J, Batot G, Whitelegge JP, Goulding CW. PMID: 26278184; PMCID: PMC4546533.
      View in: PubMed   Mentions: 18     Fields:    Translation:Cells
    75. Small lipidated anti-obesity compounds derived from neuromedin U. Eur J Med Chem. 2015 Aug 28; 101:616-26. Micewicz ED, Bahattab OS, Willars GB, Waring AJ, Navab M, Whitelegge JP, McBride WH, Ruchala P. PMID: 26204509; PMCID: PMC4543588.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimalsCells
    76. Remodeling of the plasma membrane in preparation for sperm-egg recognition: roles of acrosomal proteins. Asian J Androl. 2015 Jul-Aug; 17(4):574-82. Tanphaichitr N, Kongmanas K, Kruevaisayawan H, Saewu A, Sugeng C, Fernandes J, Souda P, Angel JB, Faull KF, Aitken RJ, Whitelegge J, Hardy D, Berger T, Baker M. PMID: 25994642; PMCID: PMC4492047.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansCells
    77. Cyclic Rhamnosylated Elongation Factor P Establishes Antibiotic Resistance in Pseudomonas aeruginosa. mBio. 2015 Jun 09; 6(3):e00823. Rajkovic A, Erickson S, Witzky A, Branson OE, Seo J, Gafken PR, Frietas MA, Whitelegge JP, Faull KF, Navarre W, Darwin AJ, Ibba M. PMID: 26060278; PMCID: PMC4471567.
      View in: PubMed   Mentions: 29     Fields:    Translation:Cells
    78. Role of domain swapping in the hetero-oligomeric cytochrome b6f lipoprotein complex. Biochemistry. 2015 May 26; 54(20):3151-63. Agarwal R, Hasan SS, Jones LM, Stofleth JT, Ryan CM, Whitelegge JP, Kehoe DM, Cramer WA. PMID: 25928281; PMCID: PMC4672631.
      View in: PubMed   Mentions: 5     Fields:    Translation:Cells
    79. Proteomic Characterization of Pig Sperm Anterior Head Plasma Membrane Reveals Roles of Acrosomal Proteins in ZP3 Binding. J Cell Physiol. 2015 Feb; 230(2):449-63. Kongmanas K, Kruevaisayawan H, Saewu A, Sugeng C, Fernandes J, Souda P, Angel JB, Faull KF, Aitken RJ, Whitelegge J, Hardy D, Berger T, Baker MA, Tanphaichitr N. PMID: 25078272.
      View in: PubMed   Mentions: 11     Fields:    Translation:AnimalsCells
    80. Septin dynamics are essential for exocytosis. J Biol Chem. 2015 Feb 27; 290(9):5280-97. Tokhtaeva E, Capri J, Marcus EA, Whitelegge JP, Khuzakhmetova V, Bukharaeva E, Deiss-Yehiely N, Dada LA, Sachs G, Fernandez-Salas E, Vagin O. PMID: 25575596; PMCID: PMC4342448.
      View in: PubMed   Mentions: 34     Fields:    Translation:HumansAnimalsCells
    81. Tctex1d2 associates with short-rib polydactyly syndrome proteins and is required for ciliogenesis. Cell Cycle. 2015; 14(7):1116-25. Gholkar AA, Senese S, Lo YC, Capri J, Deardorff WJ, Dharmarajan H, Contreras E, Hodara E, Whitelegge JP, Jackson PK, Torres JZ. PMID: 25830415; PMCID: PMC4614626.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansCells
    82. Combined phosphoproteomics and bioinformatics strategy in deciphering drug resistant related pathways in triple negative breast cancer. Int J Proteomics. 2014; 2014:390781. Deng X, Kohanfars M, Hsu HM, Souda P, Capri J, Whitelegge JP, Chang HR. PMID: 25478227; PMCID: PMC4247952.
      View in: PubMed   Mentions: 1  
    83. p16 Protein and gigaxonin are associated with the ubiquitination of NFκB in cisplatin-induced senescence of cancer cells. J Biol Chem. 2014 Dec 12; 289(50):34921-37. Veena MS, Wilken R, Zheng JY, Gholkar A, Venkatesan N, Vira D, Ahmed S, Basak SK, Dalgard CL, Ravichandran S, Batra RK, Kasahara N, Elashoff D, Fishbein MC, Whitelegge JP, Torres JZ, Wang MB, Srivatsan ES. PMID: 25331947; PMCID: PMC4263890.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansCells
    84. Structure-function of cyanobacterial outer-membrane protein, Slr1270: homolog of Escherichia coli drug export/colicin import protein, TolC. FEBS Lett. 2014 Nov 03; 588(21):3793-801. Agarwal R, Zakharov S, Hasan SS, Ryan CM, Whitelegge JP, Cramer WA. PMID: 25218435; PMCID: PMC4288923.
      View in: PubMed   Mentions: 6     Fields:    Translation:Cells
    85. Formation of amyloid fibers by monomeric light chain variable domains. J Biol Chem. 2014 Oct 03; 289(40):27513-25. Brumshtein B, Esswein SR, Landau M, Ryan CM, Whitelegge JP, Phillips ML, Cascio D, Sawaya MR, Eisenberg DS. PMID: 25138218; PMCID: PMC4183792.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansCells
    86. Identification of a unique Fe-S cluster binding site in a glycyl-radical type microcompartment shell protein. J Mol Biol. 2014 Sep 23; 426(19):3287-3304. Thompson MC, Wheatley NM, Jorda J, Sawaya MR, Gidaniyan SD, Ahmed H, Yang Z, McCarty KN, Whitelegge JP, Yeates TO. PMID: 25102080; PMCID: PMC4175982.
      View in: PubMed   Mentions: 10     Fields:    Translation:Cells
    87. Recruitment of septin cytoskeletal proteins by botulinum toxin A protease determines its remarkable stability. J Cell Sci. 2014 Aug 01; 127(Pt 15):3294-308. Vagin O, Tokhtaeva E, Garay PE, Souda P, Bassilian S, Whitelegge JP, Lewis R, Sachs G, Wheeler L, Aoki R, Fernandez-Salas E. PMID: 24928902; PMCID: PMC6518159.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansAnimalsCells
    88. Gas-phase structure of the E. coli OmpA dimer. Structure. 2014 May 06; 22(5):666-7. Whitelegge J. PMID: 24807077; PMCID: PMC5524567.
      View in: PubMed   Mentions: 5     Fields:    
    89. Non-repair pathways for minimizing protein isoaspartyl damage in the yeast Saccharomyces cerevisiae. J Biol Chem. 2014 Jun 13; 289(24):16936-53. Patananan AN, Capri J, Whitelegge JP, Clarke SG. PMID: 24764295; PMCID: PMC4059137.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansAnimalsCells
    90. Mammalian protein arginine methyltransferase 7 (PRMT7) specifically targets RXR sites in lysine- and arginine-rich regions. J Biol Chem. 2013 Dec 27; 288(52):37010-25. Feng Y, Maity R, Whitelegge JP, Hadjikyriacou A, Li Z, Zurita-Lopez C, Al-Hadid Q, Clark AT, Bedford MT, Masson JY, Clarke SG. PMID: 24247247; PMCID: PMC3873558.
      View in: PubMed   Mentions: 61     Fields:    Translation:HumansAnimalsCells
    91. Distinctive features of the D101N and D101G variants of superoxide dismutase 1; two mutations that produce rapidly progressing motor neuron disease. J Neurochem. 2014 Jan; 128(2):305-14. Ayers J, Lelie H, Workman A, Prudencio M, Brown H, Fromholt S, Valentine J, Whitelegge J, Borchelt D. PMID: 24032979; PMCID: PMC3971632.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansCells
    92. Proteogenomic Review of the Changes in Primate apoC-I during Evolution. Front Biol (Beijing). 2013 Oct; 8(5):533-548. Puppione D, Whitelegge JP. PMID: 28757862; PMCID: PMC5528196.
      View in: PubMed   Mentions:
    93. Drip, Ship, and Grip, then Slice and Dice: Comprehensive Stroke Center Management of Cervical and Intracranial Emboli. Front Neurol. 2013; 4:104. Hinman JD, Rao NM, Yallapragada A, Capri J, Souda P, Whitelegge J, Yong WH, Jahan R, Quinones-Baldrich W, Saver JL. PMID: 23908644; PMCID: PMC3725951.
      View in: PubMed   Mentions: 4  
    94. Structural similarity of wild-type and ALS-mutant superoxide dismutase-1 fibrils using limited proteolysis and atomic force microscopy. Proc Natl Acad Sci U S A. 2013 Jul 02; 110(27):10934-9. Chan PK, Chattopadhyay M, Sharma S, Souda P, Gralla EB, Borchelt DR, Whitelegge JP, Valentine JS. PMID: 23781106; PMCID: PMC3704032.
      View in: PubMed   Mentions: 23     Fields:    Translation:HumansCells
    95. Impairment of mitochondria in adult mouse brain overexpressing predominantly full-length, N-terminally acetylated human α-synuclein. PLoS One. 2013; 8(5):e63557. Sarafian TA, Ryan CM, Souda P, Masliah E, Kar UK, Vinters HV, Mathern GW, Faull KF, Whitelegge JP, Watson JB. PMID: 23667637; PMCID: PMC3646806.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansAnimalsCells
    96. Intact protein mass spectrometry and top-down proteomics. Expert Rev Proteomics. 2013 Apr; 10(2):127-9. Whitelegge J. PMID: 23573779.
      View in: PubMed   Mentions: 4     Fields:    
    97. Evidence that YycJ is a novel 5'-3' double-stranded DNA exonuclease acting in Bacillus anthracis mismatch repair. DNA Repair (Amst). 2013 May 01; 12(5):334-46. Yang H, Yung M, Li L, Hoch JA, Ryan CM, Kar UK, Souda P, Whitelegge JP, Miller JH. PMID: 23491602.
      View in: PubMed   Mentions: 4     Fields:    Translation:Cells
    98. Integral membrane proteins and bilayer proteomics. Anal Chem. 2013 Mar 05; 85(5):2558-68. Whitelegge JP. PMID: 23301778; PMCID: PMC3664232.
      View in: PubMed   Mentions: 31     Fields:    Translation:AnimalsCells
    99. A designed inhibitor of a CLC antiporter blocks function through a unique binding mode. Chem Biol. 2012 Nov 21; 19(11):1460-70. Howery AE, Elvington S, Abraham SJ, Choi KH, Dworschak-Simpson S, Phillips S, Ryan CM, Sanford RL, Almqvist J, Tran K, Chew TA, Zachariae U, Andersen OS, Whitelegge J, Matulef K, Du Bois J, Maduke MC. PMID: 23177200; PMCID: PMC3508466.
      View in: PubMed   Mentions: 14     Fields:    Translation:Cells
    100. N-terminal acetylation of annexin A2 is required for S100A10 binding. Biol Chem. 2012 Oct; 393(10):1141-50. Nazmi AR, Ozorowski G, Pejic M, Whitelegge JP, Gerke V, Luecke H. PMID: 23091277.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansCells
    101. Withaferin A binds covalently to the N-terminal domain of annexin A2. Biol Chem. 2012 Oct; 393(10):1151-63. Ozorowski G, Ryan CM, Whitelegge JP, Luecke H. PMID: 23091278.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansAnimalsCells
    102. Mass spectrometry (LC-MS/MS) identified proteomic biosignatures of breast cancer in proximal fluid. J Proteome Res. 2012 Oct 05; 11(10):5034-45. Whelan SA, He J, Lu M, Souda P, Saxton RE, Faull KF, Whitelegge JP, Chang HR. PMID: 22934887; PMCID: PMC3521600.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansCells
    103. Phenotypic and genomic analysis of hypervirulent human-associated Bordetella bronchiseptica. BMC Microbiol. 2012 Aug 06; 12:167. Ahuja U, Liu M, Tomida S, Park J, Souda P, Whitelegge J, Li H, Harvill ET, Parkhill J, Miller JF. PMID: 22863321; PMCID: PMC3462115.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansAnimalsCells
    104. Dissection of mechanistic principles of a secondary multidrug efflux protein. Mol Cell. 2012 Sep 14; 47(5):777-87. Fluman N, Ryan CM, Whitelegge JP, Bibi E. PMID: 22841484; PMCID: PMC5524571.
      View in: PubMed   Mentions: 51     Fields:    Translation:Cells
    105. Defining intact protein primary structures from saliva: a step toward the human proteome project. Anal Chem. 2012 May 15; 84(10):4383-95. Halgand F, Zabrouskov V, Bassilian S, Souda P, Loo JA, Faull KF, Wong DT, Whitelegge JP. PMID: 22509742; PMCID: PMC3367462.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCells
    106. A novel variant of human superoxide dismutase 1 harboring amyotrophic lateral sclerosis-associated and experimental mutations in metal-binding residues and free cysteines lacks toxicity in vivo. J Neurochem. 2012 May; 121(3):475-85. Prudencio M, Lelie H, Brown HH, Whitelegge JP, Valentine JS, Borchelt DR. PMID: 22332887; PMCID: PMC3705958.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansAnimalsCells
    107. Atomic view of a toxic amyloid small oligomer. Science. 2012 Mar 09; 335(6073):1228-31. Laganowsky A, Liu C, Sawaya MR, Whitelegge JP, Park J, Zhao M, Pensalfini A, Soriaga AB, Landau M, Teng PK, Cascio D, Glabe C, Eisenberg D. PMID: 22403391; PMCID: PMC3959867.
      View in: PubMed   Mentions: 242     Fields:    Translation:Cells
    108. Mass spectral measurements of the apoHDL in horse (Equus caballus) cerebrospinal fluid. Comp Biochem Physiol Part D Genomics Proteomics. 2012 Jun; 7(2):172-4. Puppione DL, Della Donna L, Bassilian S, Souda P, MacDonald MH, Whitelegge JP. PMID: 22377539.
      View in: PubMed   Mentions:    Fields:    Translation:Animals
    109. A peroxidase-dependent apoplastic oxidative burst in cultured Arabidopsis cells functions in MAMP-elicited defense. Plant Physiol. 2012 Apr; 158(4):2013-27. O'Brien JA, Daudi A, Finch P, Butt VS, Whitelegge JP, Souda P, Ausubel FM, Bolwell GP. PMID: 22319074; PMCID: PMC3320203.
      View in: PubMed   Mentions: 72     Fields:    Translation:AnimalsCells
    110. Characterization of the endothelial cell cytoskeleton following HLA class I ligation. PLoS One. 2012; 7(1):e29472. Ziegler ME, Souda P, Jin YP, Whitelegge JP, Reed EF. PMID: 22247778; PMCID: PMC3256144.
      View in: PubMed   Mentions: 21     Fields:    Translation:HumansCells
    111. SOD1 aggregation and ALS: role of metallation states and disulfide status. Curr Top Med Chem. 2012; 12(22):2560-72. Sheng Y, Chattopadhyay M, Whitelegge J, Valentine JS. PMID: 23339308.
      View in: PubMed   Mentions: 40     Fields:    Translation:HumansAnimalsCells
    112. Molecular dissection of novel trafficking and processing of the Toxoplasma gondii rhoptry metalloprotease toxolysin-1. Traffic. 2012 Feb; 13(2):292-304. Hajagos BE, Turetzky JM, Peng ED, Cheng SJ, Ryan CM, Souda P, Whitelegge JP, Lebrun M, Dubremetz JF, Bradley PJ. PMID: 22035499; PMCID: PMC3375832.
      View in: PubMed   Mentions: 26     Fields:    Translation:AnimalsCells
    113. Proteomic-based biosignatures in breast cancer classification and prediction of therapeutic response. Int J Proteomics. 2011; 2011:896476. He J, Whelan SA, Lu M, Shen D, Chung DU, Saxton RE, Faull KF, Whitelegge JP, Chang HR. PMID: 22110952; PMCID: PMC3202144.
      View in: PubMed   Mentions: 15  
    114. Structural biology. Up close with membrane lipid-protein complexes. Science. 2011 Oct 21; 334(6054):320-1. Whitelegge J. PMID: 22021848.
      View in: PubMed   Mentions: 2     Fields:    Translation:Cells
    115. Comparative proteomic analysis of differentially expressed proteins in the urine of reservoir hosts of leptospirosis. PLoS One. 2011; 6(10):e26046. Nally JE, Monahan AM, Miller IS, Bonilla-Santiago R, Souda P, Whitelegge JP. PMID: 22043303; PMCID: PMC3197145.
      View in: PubMed   Mentions: 20     Fields:    Translation:AnimalsCells
    116. Mass spectrometric measurements of the apolipoproteins of bovine (Bos taurus) HDL. Comp Biochem Physiol Part D Genomics Proteomics. 2012 Mar; 7(1):9-13. Della Donna L, Bassilian S, Souda P, Nebbia C, Whitelegge JP, Puppione DL. PMID: 22056023.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    117. Profiling of integral membrane proteins and their post translational modifications using high-resolution mass spectrometry. Methods. 2011 Dec; 55(4):330-6. Souda P, Ryan CM, Cramer WA, Whitelegge J. PMID: 21982782; PMCID: PMC3498814.
      View in: PubMed   Mentions: 13     Fields:    Translation:Cells
    118. Conservation of lipid functions in cytochrome bc complexes. J Mol Biol. 2011 Nov 18; 414(1):145-62. Hasan SS, Yamashita E, Ryan CM, Whitelegge JP, Cramer WA. PMID: 21978667; PMCID: PMC3215850.
      View in: PubMed   Mentions: 21     Fields:    Translation:Cells
    119. Epithelial junctions depend on intercellular trans-interactions between the Na,K-ATPase β₁ subunits. J Biol Chem. 2011 Jul 22; 286(29):25801-12. Tokhtaeva E, Sachs G, Souda P, Bassilian S, Whitelegge JP, Shoshani L, Vagin O. PMID: 21642423; PMCID: PMC3138299.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansAnimalsCells
    120. Diverse facets of plant proteomics. Phytochemistry. 2011 Jul; 72(10):961-2. Whitelegge JP, Komatsu S, Jorrin-Novo J. PMID: 21543094.
      View in: PubMed   Mentions:    Fields:    Translation:Animals
    121. Discovery and characterization of a unique mycobacterial heme acquisition system. Proc Natl Acad Sci U S A. 2011 Mar 22; 108(12):5051-6. Tullius MV, Harmston CA, Owens CP, Chim N, Morse RP, McMath LM, Iniguez A, Kimmey JM, Sawaya MR, Whitelegge JP, Horwitz MA, Goulding CW. PMID: 21383189; PMCID: PMC3064333.
      View in: PubMed   Mentions: 103     Fields:    Translation:Cells
    122. NdhP and NdhQ: two novel small subunits of the cyanobacterial NDH-1 complex. Biochemistry. 2011 Feb 22; 50(7):1121-4. Nowaczyk MM, Wulfhorst H, Ryan CM, Souda P, Zhang H, Cramer WA, Whitelegge JP. PMID: 21244052; PMCID: PMC3040284.
      View in: PubMed   Mentions: 29     Fields:    Translation:Cells
    123. Efficient light harvesting in a dark, hot, acidic environment: the structure and function of PSI-LHCI from Galdieria sulphuraria. Biophys J. 2011 Jan 05; 100(1):135-43. Thangaraj B, Jolley CC, Sarrou I, Bultema JB, Greyslak J, Whitelegge JP, Lin S, Kouril R, Subramanyam R, Boekema EJ, Fromme P. PMID: 21190665; PMCID: PMC3010194.
      View in: PubMed   Mentions: 15     Fields:    Translation:AnimalsCells
    124. Biomarkers to predict antidepressant response. Curr Psychiatry Rep. 2010 Dec; 12(6):553-62. Leuchter AF, Cook IA, Hamilton SP, Narr KL, Toga A, Hunter AM, Faull K, Whitelegge J, Andrews AM, Loo J, Way B, Nelson SF, Horvath S, Lebowitz BD. PMID: 20963521; PMCID: PMC2965366.
      View in: PubMed   Mentions: 57     Fields:    Translation:Humans
    125. Amniotic and allantoic fluids from experimentally infected sheep contain immunoglobulin specific for Chlamydophila abortus. Vet Immunol Immunopathol. 2011 Mar 15; 140(1-2):1-9. Marques PX, O'Donovan J, Souda P, Gutierrez J, Williams EJ, Worrall S, McElroy M, Proctor A, Brady C, Sammin D, Basset H, Whitelegge JP, Markey BK, Nally JE. PMID: 21126774.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    126. Copper and zinc metallation status of copper-zinc superoxide dismutase from amyotrophic lateral sclerosis transgenic mice. J Biol Chem. 2011 Jan 28; 286(4):2795-806. Lelie HL, Liba A, Bourassa MW, Chattopadhyay M, Chan PK, Gralla EB, Miller LM, Borchelt DR, Valentine JS, Whitelegge JP. PMID: 21068388; PMCID: PMC3024775.
      View in: PubMed   Mentions: 47     Fields:    Translation:HumansAnimals
    127. Adaptation to a high-tungsten environment: Pyrobaculum aerophilum contains an active tungsten nitrate reductase. Biochemistry. 2010 Nov 16; 49(45):9911-21. de Vries S, Momcilovic M, Strampraad MJ, Whitelegge JP, Baghai A, Schröder I. PMID: 20863064.
      View in: PubMed   Mentions: 12     Fields:    Translation:Cells
    128. Data-directed top-down Fourier-transform mass spectrometry of a large integral membrane protein complex: photosystem II from Galdieria sulphuraria. Proteomics. 2010 Oct; 10(20):3644-56. Thangaraj B, Ryan CM, Souda P, Krause K, Faull KF, Weber AP, Fromme P, Whitelegge JP. PMID: 20845333; PMCID: PMC3517113.
      View in: PubMed   Mentions: 26     Fields:    Translation:AnimalsCells
    129. An examination of wild-type SOD1 in modulating the toxicity and aggregation of ALS-associated mutant SOD1. Hum Mol Genet. 2010 Dec 15; 19(24):4774-89. Prudencio M, Durazo A, Whitelegge JP, Borchelt DR. PMID: 20871097; PMCID: PMC2989888.
      View in: PubMed   Mentions: 36     Fields:    Translation:AnimalsCells
    130. A novel 3-methylhistidine modification of yeast ribosomal protein Rpl3 is dependent upon the YIL110W methyltransferase. J Biol Chem. 2010 Nov 26; 285(48):37598-606. Webb KJ, Zurita-Lopez CI, Al-Hadid Q, Laganowsky A, Young BD, Lipson RS, Souda P, Faull KF, Whitelegge JP, Clarke SG. PMID: 20864530; PMCID: PMC2988365.
      View in: PubMed   Mentions: 38     Fields:    Translation:AnimalsCells
    131. Deconvolution and database search of complex tandem mass spectra of intact proteins: a combinatorial approach. Mol Cell Proteomics. 2010 Dec; 9(12):2772-82. Liu X, Inbar Y, Dorrestein PC, Wynne C, Edwards N, Souda P, Whitelegge JP, Bafna V, Pevzner PA. PMID: 20855543; PMCID: PMC3101958.
      View in: PubMed   Mentions: 73     Fields:    Translation:Cells
    132. Hydrophobic Proteome Analysis of Triple Negative and Hormone-Receptor-Positive-Her2-Negative Breast Cancer by Mass Spectrometer. Clin Proteomics. 2010 Sep; 6(3):93-103. Lu M, Whelan SA, He J, Saxton RE, Faull KF, Whitelegge JP, Chang HR. PMID: 20930921; PMCID: PMC2937135.
      View in: PubMed   Mentions: 6  
    133. PYY(1-36) is the major form of PYY in rat distal small intestine: quantification using high-resolution mass spectrometry. Regul Pept. 2010 Dec 10; 165(2-3):151-7. Keire DA, Whitelegge JP, Souda P, Faull KF, Bassilian S, Reidelberger RD, Haver AC, Reeve JR. PMID: 20615437; PMCID: PMC3971906.
      View in: PubMed   Mentions: 4     Fields:    Translation:Animals
    134. Identification of protein N-terminal methyltransferases in yeast and humans. Biochemistry. 2010 Jun 29; 49(25):5225-35. Webb KJ, Lipson RS, Al-Hadid Q, Whitelegge JP, Clarke SG. PMID: 20481588; PMCID: PMC2890028.
      View in: PubMed   Mentions: 47     Fields:    Translation:HumansAnimalsCells
    135. Identification of immunologically relevant proteins of Chlamydophila abortus using sera from experimentally infected pregnant ewes. Clin Vaccine Immunol. 2010 Aug; 17(8):1274-81. Marques PX, Souda P, O'Donovan J, Gutierrez J, Gutierrez EJ, Worrall S, McElroy M, Proctor A, Brady C, Sammin D, Basset HF, Whitelegge JP, Markey BE, Nally JE. PMID: 20554807; PMCID: PMC2916250.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    136. A novel EF-hand protein, CRACR2A, is a cytosolic Ca2+ sensor that stabilizes CRAC channels in T cells. Nat Cell Biol. 2010 May; 12(5):436-46. Srikanth S, Jung HJ, Kim KD, Souda P, Whitelegge J, Gwack Y. PMID: 20418871; PMCID: PMC2875865.
      View in: PubMed   Mentions: 113     Fields:    Translation:HumansCells
    137. Cysteine string protein beta is prominently associated with nerve terminals and secretory organelles in mouse brain. Brain Res. 2010 May 21; 1332:1-11. Gundersen CB, Kohan SA, Souda P, Whitelegge JP, Umbach JA. PMID: 20338151.
      View in: PubMed   Mentions: 6     Fields:    Translation:AnimalsCells
    138. Isolation and identification of cytoskeleton-associated prolamine mRNA binding proteins from developing rice seeds. Planta. 2010 May; 231(6):1261-76. Crofts AJ, Crofts N, Whitelegge JP, Okita TW. PMID: 20217123.
      View in: PubMed   Mentions: 21     Fields:    Translation:AnimalsCells
    139. Detection of two distinct forms of apoC-I in great apes. Comp Biochem Physiol Part D Genomics Proteomics. 2010 Mar; 5(1):73-9. Puppione DL, Ryan CM, Bassilian S, Souda P, Xiao X, Ryder OA, Whitelegge JP. PMID: 20209111; PMCID: PMC2830554.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansAnimalsCells
    140. Identification of differentially expressed proteins in murine embryonic and postnatal cortical neural progenitors. PLoS One. 2010 Feb 09; 5(2):e9121. Shoemaker LD, Orozco NM, Geschwind DH, Whitelegge JP, Faull KF, Kornblum HI. PMID: 20161753; PMCID: PMC2817745.
      View in: PubMed   Mentions: 5     Fields:    Translation:AnimalsCells
    141. Confident assignment of intact mass tags to human salivary cystatins using top-down Fourier-transform ion cyclotron resonance mass spectrometry. J Am Soc Mass Spectrom. 2010 Jun; 21(6):908-17. Ryan CM, Souda P, Halgand F, Wong DT, Loo JA, Faull KF, Whitelegge JP. PMID: 20189825; PMCID: PMC2873128.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansCells
    142. Micro-heterogeneity of human saliva Peptide P-C characterized by high-resolution top-down Fourier-transform mass spectrometry. J Am Soc Mass Spectrom. 2010 May; 21(5):868-77. Halgand F, Zabrouskov V, Bassilian S, Souda P, Wong DT, Loo JA, Faull KF, Whitelegge JP. PMID: 20185333.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCells
    143. Hydrophobic Fractionation Enhances Novel Protein Detection by Mass Spectrometry in Triple Negative Breast Cancer. J Proteomics Bioinform. 2010 Jan 22; 3(2):1-10. Lu M, Whitelegge JP, Whelan SA, He J, Saxton RE, Faull KF, Chang HR. PMID: 20596302; PMCID: PMC2894735.
      View in: PubMed   Mentions: 3  
    144. Post-translational modifications of integral membrane proteins resolved by top-down Fourier transform mass spectrometry with collisionally activated dissociation. Mol Cell Proteomics. 2010 May; 9(5):791-803. Ryan CM, Souda P, Bassilian S, Ujwal R, Zhang J, Abramson J, Ping P, Durazo A, Bowie JU, Hasan SS, Baniulis D, Cramer WA, Faull KF, Whitelegge JP. PMID: 20093275; PMCID: PMC2871414.
      View in: PubMed   Mentions: 49     Fields:    Translation:AnimalsCells
    145. An extracellular disulfide bond forming protein (DsbF) from Mycobacterium tuberculosis: structural, biochemical, and gene expression analysis. J Mol Biol. 2010 Mar 12; 396(5):1211-26. Chim N, Riley R, The J, Im S, Segelke B, Lekin T, Yu M, Hung LW, Terwilliger T, Whitelegge JP, Goulding CW. PMID: 20060836; PMCID: PMC2883863.
      View in: PubMed   Mentions: 13     Fields:    Translation:Cells
    146. Taking charge of proteins from neurodegeneration to industrial biotechnology. Adv Protein Chem Struct Biol. 2010; 79:127-64. Shaw BF, Moustakas DT, Whitelegge JP, Faull KF. PMID: 20621283.
      View in: PubMed   Mentions: 5     Fields:    Translation:Cells
    147. Mass spectral analyses of the two major apolipoproteins of great ape high density lipoproteins. Comp Biochem Physiol Part D Genomics Proteomics. 2009 12; 4(4):305-309. Puppione DL, Della Donna L, Laganowsky AD, Bassilian S, Souda P, Ryder OA, Whitelegge JP. PMID: 21298813; PMCID: PMC2776726.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    148. Anthrax lethal toxin induced lysosomal membrane permeabilization and cytosolic cathepsin release is Nlrp1b/Nalp1b-dependent. PLoS One. 2009 Nov 18; 4(11):e7913. Averette KM, Pratt MR, Yang Y, Bassilian S, Whitelegge JP, Loo JA, Muir TW, Bradley KA. PMID: 19924255; PMCID: PMC2775945.
      View in: PubMed   Mentions: 30     Fields:    Translation:AnimalsCells
    149. Intramolecular amide bonds stabilize pili on the surface of bacilli. Proc Natl Acad Sci U S A. 2009 Nov 24; 106(47):19992-7. Budzik JM, Poor CB, Faull KF, Whitelegge JP, He C, Schneewind O. PMID: 19903875; PMCID: PMC2785280.
      View in: PubMed   Mentions: 41     Fields:    Translation:Cells
    150. Rpe65 isomerase associates with membranes through an electrostatic interaction with acidic phospholipid headgroups. J Biol Chem. 2010 Jan 08; 285(2):988-99. Yuan Q, Kaylor JJ, Miu A, Bassilian S, Whitelegge JP, Travis GH. PMID: 19892706; PMCID: PMC2801300.
      View in: PubMed   Mentions: 6     Fields:    Translation:AnimalsCells
    151. Structural studies of the Sputnik virophage. J Virol. 2010 Jan; 84(2):894-7. Sun S, La Scola B, Bowman VD, Ryan CM, Whitelegge JP, Raoult D, Rossmann MG. PMID: 19889775; PMCID: PMC2798384.
      View in: PubMed   Mentions: 22     Fields:    Translation:AnimalsCells
    152. Metal-free superoxide dismutase-1 and three different amyotrophic lateral sclerosis variants share a similar partially unfolded beta-barrel at physiological temperature. J Biol Chem. 2009 Dec 04; 284(49):34382-9. Durazo A, Shaw BF, Chattopadhyay M, Faull KF, Nersissian AM, Valentine JS, Whitelegge JP. PMID: 19805550; PMCID: PMC2797206.
      View in: PubMed   Mentions: 26     Fields:    Translation:HumansCells
    153. Tumor proteomic profiling predicts the susceptibility of breast cancer to chemotherapy. Int J Oncol. 2009 Oct; 35(4):683-92. He J, Shen D, Chung DU, Saxton RE, Whitelegge JP, Faull KF, Chang HR. PMID: 19724903.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansCTClinical Trials
    154. Similar energetic contributions of packing in the core of membrane and water-soluble proteins. J Am Chem Soc. 2009 Aug 12; 131(31):10846-7. Joh NH, Oberai A, Yang D, Whitelegge JP, Bowie JU. PMID: 19603754; PMCID: PMC2744480.
      View in: PubMed   Mentions: 35     Fields:    Translation:Cells
    155. Mass spectrometry (LC-MS/MS) site-mapping of N-glycosylated membrane proteins for breast cancer biomarkers. J Proteome Res. 2009 Aug; 8(8):4151-60. Whelan SA, Lu M, He J, Yan W, Saxton RE, Faull KF, Whitelegge JP, Chang HR. PMID: 19522481; PMCID: PMC2761014.
      View in: PubMed   Mentions: 33     Fields:    Translation:HumansCells
    156. The cell wall and secretory proteome of a tobacco cell line synthesising secondary wall. Proteomics. 2009 May; 9(9):2355-72. Millar DJ, Whitelegge JP, Bindschedler LV, Rayon C, Boudet AM, Rossignol M, Borderies G, Bolwell GP. PMID: 19402043.
      View in: PubMed   Mentions: 11     Fields:    Translation:AnimalsCells
    157. Hydroponics on a chip: analysis of the Fe deficient Arabidopsis thylakoid membrane proteome. J Proteomics. 2009 Apr 13; 72(3):397-415. Laganowsky A, Gómez SM, Whitelegge JP, Nishio JN. PMID: 19367733.
      View in: PubMed   Mentions: 15     Fields:    Translation:AnimalsCells
    158. Mapping of a copper-binding site on the small CP12 chloroplastic protein of Chlamydomonas reinhardtii using top-down mass spectrometry and site-directed mutagenesis. Biochem J. 2009 Apr 01; 419(1):75-82, 4 p following 82. Erales J, Gontero B, Whitelegge J, Halgand F. PMID: 19099541.
      View in: PubMed   Mentions: 13     Fields:    Translation:AnimalsCells
    159. Structure-Function, Stability, and Chemical Modification of the Cyanobacterial Cytochrome b6f Complex from Nostoc sp. PCC 7120. J Biol Chem. 2009 Apr 10; 284(15):9861-9. Baniulis D, Yamashita E, Whitelegge JP, Zatsman AI, Hendrich MP, Hasan SS, Ryan CM, Cramer WA. PMID: 19189962; PMCID: PMC2665108.
      View in: PubMed   Mentions: 45     Fields:    Translation:Cells
    160. Hepatic lipase maturation: a partial proteome of interacting factors. J Lipid Res. 2009 Jun; 50(6):1173-84. Doolittle MH, Ben-Zeev O, Bassilian S, Whitelegge JP, Péterfy M, Wong H. PMID: 19136429; PMCID: PMC2681399.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansAnimalsCells
    161. Modulation of mutant superoxide dismutase 1 aggregation by co-expression of wild-type enzyme. J Neurochem. 2009 Feb; 108(4):1009-18. Prudencio M, Durazo A, Whitelegge JP, Borchelt DR. PMID: 19077113; PMCID: PMC2801375.
      View in: PubMed   Mentions: 26     Fields:    Translation:HumansAnimalsCells
    162. Initiation and elongation in fibrillation of ALS-linked superoxide dismutase. Proc Natl Acad Sci U S A. 2008 Dec 02; 105(48):18663-8. Chattopadhyay M, Durazo A, Sohn SH, Strong CD, Gralla EB, Whitelegge JP, Valentine JS. PMID: 19022905; PMCID: PMC2585484.
      View in: PubMed   Mentions: 104     Fields:    Translation:HumansAnimalsCells
    163. Identification of two SET domain proteins required for methylation of lysine residues in yeast ribosomal protein Rpl42ab. J Biol Chem. 2008 Dec 19; 283(51):35561-8. Webb KJ, Laganowsky A, Whitelegge JP, Clarke SG. PMID: 18957409; PMCID: PMC2602916.
      View in: PubMed   Mentions: 25     Fields:    Translation:AnimalsCells
    164. Mass spectral analysis of the apolipoproteins on dog (Canis lupus familiaris) high density lipoproteins. Detection of apolipoprotein A-II. Comp Biochem Physiol Part D Genomics Proteomics. 2008 Dec; 3(4):290-6. Puppione DL, Bassilian S, Souda P, MacDonald MH, Halgand F, Hagland F, Whitelegge JP. PMID: 20483223.
      View in: PubMed   Mentions: 5     Fields:    
    165. Amide bonds assemble pili on the surface of bacilli. Proc Natl Acad Sci U S A. 2008 Jul 22; 105(29):10215-20. Budzik JM, Marraffini LA, Souda P, Whitelegge JP, Faull KF, Schneewind O. PMID: 18621716; PMCID: PMC2481347.
      View in: PubMed   Mentions: 42     Fields:    Translation:Cells
    166. Revealing the dynamics of the 20 S proteasome phosphoproteome: a combined CID and electron transfer dissociation approach. Mol Cell Proteomics. 2008 Nov; 7(11):2073-89. Lu H, Zong C, Wang Y, Young GW, Deng N, Souda P, Li X, Whitelegge J, Drews O, Yang PY, Ping P. PMID: 18579562; PMCID: PMC2577207.
      View in: PubMed   Mentions: 43     Fields:    Translation:AnimalsCells
    167. Modest stabilization by most hydrogen-bonded side-chain interactions in membrane proteins. Nature. 2008 Jun 26; 453(7199):1266-70. Joh NH, Min A, Faham S, Whitelegge JP, Yang D, Woods VL, Bowie JU. PMID: 18500332; PMCID: PMC2734483.
      View in: PubMed   Mentions: 97     Fields:    Translation:Cells
    168. Lysine acetylation can generate highly charged enzymes with increased resistance toward irreversible inactivation. Protein Sci. 2008 Aug; 17(8):1446-55. Shaw BF, Schneider GF, Bilgiçer B, Kaufman GK, Neveu JM, Lane WS, Whitelegge JP, Whitesides GM. PMID: 18451358; PMCID: PMC2492826.
      View in: PubMed   Mentions: 17     Fields:    Translation:Cells
    169. A new endogenous form of PYY isolated from canine ileum: Gly-extended PYY(1-36). Regul Pept. 2008 Nov 29; 151(1-3):61-70. Keire DA, Whitelegge JP, Bassilian S, Faull KF, Wiggins BW, Mehdizadeh OB, Reidelberger RD, Haver AC, Sayegh AI, Reeve JR. PMID: 18501442.
      View in: PubMed   Mentions: 5     Fields:    Translation:AnimalsCells
    170. The proteomes of human parotid and submandibular/sublingual gland salivas collected as the ductal secretions. J Proteome Res. 2008 May; 7(5):1994-2006. Denny P, Hagen FK, Hardt M, Liao L, Yan W, Arellanno M, Bassilian S, Bedi GS, Boontheung P, Cociorva D, Delahunty CM, Denny T, Dunsmore J, Faull KF, Gilligan J, Gonzalez-Begne M, Halgand F, Hall SC, Han X, Henson B, Hewel J, Hu S, Jeffrey S, Jiang J, Loo JA, Ogorzalek Loo RR, Malamud D, Melvin JE, Miroshnychenko O, Navazesh M, Niles R, Park SK, Prakobphol A, Ramachandran P, Richert M, Robinson S, Sondej M, Souda P, Sullivan MA, Takashima J, Than S, Wang J, Whitelegge JP, Witkowska HE, Wolinsky L, Xie Y, Xu T, Yu W, Ytterberg J, Wong DT, Yates JR, Fisher SJ. PMID: 18361515; PMCID: PMC2839126.
      View in: PubMed   Mentions: 142     Fields:    Translation:Humans
    171. Detergent-insoluble aggregates associated with amyotrophic lateral sclerosis in transgenic mice contain primarily full-length, unmodified superoxide dismutase-1. J Biol Chem. 2008 Mar 28; 283(13):8340-50. Shaw BF, Lelie HL, Durazo A, Nersissian AM, Xu G, Chan PK, Gralla EB, Tiwari A, Hayward LJ, Borchelt DR, Valentine JS, Whitelegge JP. PMID: 18192269; PMCID: PMC2276386.
      View in: PubMed   Mentions: 41     Fields:    Translation:HumansAnimals
    172. Mapping the cofilin binding site on yeast G-actin by chemical cross-linking. J Mol Biol. 2008 Mar 21; 377(2):395-409. Grintsevich EE, Benchaar SA, Warshaviak D, Boontheung P, Halgand F, Whitelegge JP, Faull KF, Loo RR, Sept D, Loo JA, Reisler E. PMID: 18258262; PMCID: PMC3052258.
      View in: PubMed   Mentions: 22     Fields:    Translation:AnimalsCells
    173. Rhizobium common nod genes are required for biofilm formation. Mol Microbiol. 2008 Feb; 67(3):504-15. Fujishige NA, Lum MR, De Hoff PL, Whitelegge JP, Faull KF, Hirsch AM. PMID: 18086203.
      View in: PubMed   Mentions: 21     Fields:    Translation:Cells
    174. Plant peptides and peptidomics. Plant Biotechnol J. 2008 Feb; 6(2):105-34. Farrokhi N, Whitelegge JP, Brusslan JA. PMID: 18069950.
      View in: PubMed   Mentions: 30     Fields:    
    175. Protein-Sequence Polymorphisms and Post-translational Modifications in Proteins from Human Saliva using Top-Down Fourier-transform Ion Cyclotron Resonance Mass Spectrometry. Int J Mass Spectrom. 2007 Dec 01; 268(2-3):190-197. Whitelegge JP, Zabrouskov V, Halgand F, Souda P, Bassilian S, Yan W, Wolinsky L, Loo JA, Wong DT, Faull KF. PMID: 19050733; PMCID: PMC2131703.
      View in: PubMed   Mentions: 24  
    176. Proteomics and mass spectrometry for cancer biomarker discovery. Biomark Insights. 2007 Oct 03; 2:347-60. Lu M, Faull KF, Whitelegge JP, He J, Shen D, Saxton RE, Chang HR. PMID: 19662217; PMCID: PMC2717808.
      View in: PubMed   Mentions: 8  
    177. Proteomic strategies to elucidate pathogenic mechanisms of spirochetes. Proteomics Clin Appl. 2007 Sep; 1(9):1185-97. Nally JE, Whitelegge JP, Carroll JA. PMID: 21136767.
      View in: PubMed   Mentions: 3     Fields:    
    178. The minimum information about a proteomics experiment (MIAPE). Nat Biotechnol. 2007 Aug; 25(8):887-93. Taylor CF, Paton NW, Lilley KS, Binz PA, Julian RK, Jones AR, Zhu W, Apweiler R, Aebersold R, Deutsch EW, Dunn MJ, Heck AJ, Leitner A, Macht M, Mann M, Martens L, Neubert TA, Patterson SD, Ping P, Seymour SL, Souda P, Tsugita A, Vandekerckhove J, Vondriska TM, Whitelegge JP, Wilkins MR, Xenarios I, Yates JR, Hermjakob H. PMID: 17687369.
      View in: PubMed   Mentions: 224     Fields:    Translation:Humans
    179. Murine gammaherpesvirus 68 ORF52 encodes a tegument protein required for virion morphogenesis in the cytoplasm. J Virol. 2007 Sep; 81(18):10137-50. Bortz E, Wang L, Jia Q, Wu TT, Whitelegge JP, Deng H, Zhou ZH, Sun R. PMID: 17634243; PMCID: PMC2045416.
      View in: PubMed   Mentions: 28     Fields:    Translation:HumansAnimalsCells
    180. The mitochondrial inner membrane protein mitofilin exists as a complex with SAM50, metaxins 1 and 2, coiled-coil-helix coiled-coil-helix domain-containing protein 3 and 6 and DnaJC11. FEBS Lett. 2007 Jul 24; 581(18):3545-9. Xie J, Marusich MF, Souda P, Whitelegge J, Capaldi RA. PMID: 17624330.
      View in: PubMed   Mentions: 82     Fields:    Translation:HumansAnimalsCells
    181. Metal-free superoxide dismutase forms soluble oligomers under physiological conditions: a possible general mechanism for familial ALS. Proc Natl Acad Sci U S A. 2007 Jul 03; 104(27):11263-7. Banci L, Bertini I, Durazo A, Girotto S, Gralla EB, Martinelli M, Valentine JS, Vieru M, Whitelegge JP. PMID: 17592131; PMCID: PMC1899188.
      View in: PubMed   Mentions: 109     Fields:    Translation:HumansAnimals
    182. Differential association of hemoglobin with proinflammatory high density lipoproteins in atherogenic/hyperlipidemic mice. A novel biomarker of atherosclerosis. J Biol Chem. 2007 Aug 10; 282(32):23698-707. Watanabe J, Chou KJ, Liao JC, Miao Y, Meng HH, Ge H, Grijalva V, Hama S, Kozak K, Buga G, Whitelegge JP, Lee TD, Farias-Eisner R, Navab M, Fogelman AM, Reddy ST. PMID: 17556366.
      View in: PubMed   Mentions: 36     Fields:    Translation:HumansAnimals
    183. Increased coverage in the transmembrane domain with activated-ion electron capture dissociation for top-down Fourier-transform mass spectrometry of integral membrane proteins. J Proteome Res. 2007 Jun; 6(6):2205-10. Zabrouskov V, Whitelegge JP. PMID: 17441748.
      View in: PubMed   Mentions: 27     Fields:    Translation:AnimalsCells
    184. Discovery of a thermophilic protein complex stabilized by topologically interlinked chains. J Mol Biol. 2007 May 18; 368(5):1332-44. Boutz DR, Cascio D, Whitelegge J, Perry LJ, Yeates TO. PMID: 17395198; PMCID: PMC1955483.
      View in: PubMed   Mentions: 30     Fields:    Translation:Cells
    185. Identification of a novel phosphorylation site in c-jun directly targeted in vitro by protein kinase D. Biochem Biophys Res Commun. 2007 May 04; 356(2):361-7. Waldron RT, Whitelegge JP, Faull KF, Rozengurt E. PMID: 17359934; PMCID: PMC2765859.
      View in: PubMed   Mentions: 11     Fields:    Translation:AnimalsCells
    186. Yeast ribosomal/cytochrome c SET domain methyltransferase subfamily: identification of Rpl23ab methylation sites and recognition motifs. J Biol Chem. 2007 Apr 27; 282(17):12368-76. Porras-Yakushi TR, Whitelegge JP, Clarke S. PMID: 17327221.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansAnimalsCells
    187. A membrane receptor for retinol binding protein mediates cellular uptake of vitamin A. Science. 2007 Feb 09; 315(5813):820-5. Kawaguchi R, Yu J, Honda J, Hu J, Whitelegge J, Ping P, Wiita P, Bok D, Sun H. PMID: 17255476.
      View in: PubMed   Mentions: 336     Fields:    Translation:HumansAnimalsCells
    188. Detection of breast cancer biomarkers in nipple aspirate fluid by SELDI-TOF and their identification by combined liquid chromatography-tandem mass spectrometry. Int J Oncol. 2007 Jan; 30(1):145-54. He J, Gornbein J, Shen D, Lu M, Rovai LE, Shau H, Katz J, Whitelegge JP, Faull KF, Chang HR. PMID: 17143523.
      View in: PubMed   Mentions: 14     Fields:    Translation:Humans
    189. Top-down mass spectrometry of integral membrane proteins. Expert Rev Proteomics. 2006 Dec; 3(6):585-96. Whitelegge J, Halgand F, Souda P, Zabrouskov V. PMID: 17181473.
      View in: PubMed   Mentions: 34     Fields:    Translation:HumansAnimals
    190. Characterization of the outer membrane proteome of Leptospira interrogans expressed during acute lethal infection. Infect Immun. 2007 Feb; 75(2):766-73. Nally JE, Whitelegge JP, Bassilian S, Blanco DR, Lovett MA. PMID: 17101664; PMCID: PMC1828474.
      View in: PubMed   Mentions: 54     Fields:    Translation:AnimalsCells
    191. A novel SET domain methyltransferase in yeast: Rkm2-dependent trimethylation of ribosomal protein L12ab at lysine 10. J Biol Chem. 2006 Nov 24; 281(47):35835-45. Porras-Yakushi TR, Whitelegge JP, Clarke S. PMID: 17005568.
      View in: PubMed   Mentions: 29     Fields:    Translation:AnimalsCells
    192. Exercise affects energy metabolism and neural plasticity-related proteins in the hippocampus as revealed by proteomic analysis. Eur J Neurosci. 2006 Sep; 24(5):1265-76. Ding Q, Vaynman S, Souda P, Whitelegge JP, Gomez-Pinilla F. PMID: 16987214.
      View in: PubMed   Mentions: 65     Fields:    Translation:Animals
    193. Mass spectral analysis of the apolipoproteins on mouse high density lipoproteins. Detection of post-translational modifications. Biochim Biophys Acta. 2006 Aug; 1764(8):1363-71. Puppione DL, Yam LM, Bassilian S, Souda P, Castellani LW, Schumaker VN, Whitelegge JP. PMID: 16876491.
      View in: PubMed   Mentions: 6     Fields:    Translation:AnimalsCells
    194. Local unfolding in a destabilized, pathogenic variant of superoxide dismutase 1 observed with H/D exchange and mass spectrometry. J Biol Chem. 2006 Jun 30; 281(26):18167-76. Shaw BF, Durazo A, Nersissian AM, Whitelegge JP, Faull KF, Valentine JS. PMID: 16644738.
      View in: PubMed   Mentions: 35     Fields:    Translation:HumansCells
    195. Sequencing covalent modifications of membrane proteins. J Exp Bot. 2006; 57(7):1515-22. Whitelegge JP, Laganowsky A, Nishio J, Souda P, Zhang H, Cramer WA. PMID: 16574746.
      View in: PubMed   Mentions: 6     Fields:    Translation:Cells
    196. A two component chitin-binding protein from French bean -- association of a proline-rich protein with a cysteine-rich polypeptide. FEBS Lett. 2006 Mar 06; 580(6):1541-6. Bindschedler LV, Whitelegge JP, Millar DJ, Bolwell GP. PMID: 16480721.
      View in: PubMed   Mentions: 20     Fields:    Translation:AnimalsCells
    197. Mae inhibits Pointed-P2 transcriptional activity by blocking its MAPK docking site. EMBO J. 2006 Jan 11; 25(1):70-9. Qiao F, Harada B, Song H, Whitelegge J, Courey AJ, Bowie JU. PMID: 16362034; PMCID: PMC1356365.
      View in: PubMed   Mentions: 15     Fields:    Translation:AnimalsCells
    198. Characterization of serum biomarkers for detection of early stage ovarian cancer. Proteomics. 2005 Nov; 5(17):4589-96. Kozak KR, Su F, Whitelegge JP, Faull K, Reddy S, Farias-Eisner R. PMID: 16237736.
      View in: PubMed   Mentions: 97     Fields:    Translation:Humans
    199. Mass spectral analysis of domestic and wild equine apoA-I and A-II: detection of unique dimeric forms of apoA-II. Comp Biochem Physiol B Biochem Mol Biol. 2005 Dec; 142(4):369-73. Puppione DL, Whitelegge JP, Yam LM, Bassilian S, Schumaker VN, MacDonald MH. PMID: 16230041.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    200. A novel SET domain methyltransferase modifies ribosomal protein Rpl23ab in yeast. J Biol Chem. 2005 Oct 14; 280(41):34590-8. Porras-Yakushi TR, Whitelegge JP, Miranda TB, Clarke S. PMID: 16096273.
      View in: PubMed   Mentions: 26     Fields:    Translation:AnimalsCells
    201. Cardiovascular-related proteins identified in human plasma by the HUPO Plasma Proteome Project pilot phase. Proteomics. 2005 Aug; 5(13):3520-30. Berhane BT, Zong C, Liem DA, Huang A, Le S, Edmondson RD, Jones RC, Qiao X, Whitelegge JP, Ping P, Vondriska TM. PMID: 16052623.
      View in: PubMed   Mentions: 26     Fields:    Translation:HumansCells
    202. Interactions between partner switcher orthologs BtrW and BtrV regulate type III secretion in Bordetella. J Bacteriol. 2005 Aug; 187(16):5665-76. Kozak NA, Mattoo S, Foreman-Wykert AK, Whitelegge JP, Miller JF. PMID: 16077112; PMCID: PMC1196064.
      View in: PubMed   Mentions: 26     Fields:    Translation:Cells
    203. A novel mass spectrometric assay for the cerebroside sulfate activator protein (saposin B) and arylsulfatase A. J Lipid Res. 2005 Oct; 46(10):2254-64. Norris AJ, Whitelegge JP, Yaghoubian A, Alattia JR, Privé GG, Toyokuni T, Sun H, Brooks MN, Panza L, Matto P, Compostella F, Remmel N, Klingenstein R, Sandhoff K, Fluharty C, Fluharty A, Faull KF. PMID: 16061947.
      View in: PubMed   Mentions: 6     Fields:    Translation:Animals
    204. The novel gene EG-1 stimulates cellular proliferation. Cancer Res. 2005 Jul 15; 65(14):6159-66. Lu M, Zhang L, Maul RS, Sartippour MR, Norris A, Whitelegge J, Rao JY, Brooks MN. PMID: 16024617.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansAnimalsCells
    205. The murine cardiac 26S proteasome: an organelle awaiting exploration. Ann N Y Acad Sci. 2005 Jun; 1047:197-207. Gomes AV, Zong C, Edmondson RD, Berhane BT, Wang GW, Le S, Young G, Zhang J, Vondriska TM, Whitelegge JP, Jones RC, Joshua IG, Thyparambil S, Pantaleon D, Qiao J, Loo J, Ping P. PMID: 16093497.
      View in: PubMed   Mentions: 9     Fields:    Translation:AnimalsCells
    206. A monoclonal antibody that conveys in vitro killing and partial protection in experimental syphilis binds a phosphorylcholine surface epitope of Treponema pallidum. Infect Immun. 2005 May; 73(5):3083-95. Blanco DR, Champion CI, Dooley A, Cox DL, Whitelegge JP, Faull K, Lovett MA. PMID: 15845516; PMCID: PMC1087381.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansAnimalsCells
    207. Mass spectral analysis of pig (Sus scrofa) apo HDL: Identification of pig apoA-II, a dimeric apolipoprotein. Comp Biochem Physiol B Biochem Mol Biol. 2005 May; 141(1):89-94. Puppione DL, Whitelegge JP, Yam LM, Schumaker VN. PMID: 15820138.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimalsCells
    208. Mass spectrometry for high throughput quantitative proteomics in plant research: lessons from thylakoid membranes. Plant Physiol Biochem. 2004 Dec; 42(12):919-27. Whitelegge JP. PMID: 15707830.
      View in: PubMed   Mentions: 8     Fields:    Translation:AnimalsCells
    209. J-domain protein CDJ2 and HSP70B are a plastidic chaperone pair that interacts with vesicle-inducing protein in plastids 1. Mol Biol Cell. 2005 Mar; 16(3):1165-77. Liu C, Willmund F, Whitelegge JP, Hawat S, Knapp B, Lodha M, Schroda M. PMID: 15635096; PMCID: PMC551482.
      View in: PubMed   Mentions: 56     Fields:    Translation:AnimalsCells
    210. Purification and proteomic analysis of outer membrane vesicles from a clinical isolate of Leptospira interrogans serovar Copenhageni. Proteomics. 2005 Jan; 5(1):144-52. Nally JE, Whitelegge JP, Aguilera R, Pereira MM, Blanco DR, Lovett MA. PMID: 15672460.
      View in: PubMed   Mentions: 30     Fields:    Translation:Cells
    211. Exploring the role of a unique carboxyl residue in EmrE by mass spectrometry. J Biol Chem. 2005 Mar 04; 280(9):7487-92. Weinglass AB, Soskine M, Vazquez-Ibar JL, Whitelegge JP, Faull KF, Kaback HR, Schuldiner S. PMID: 15623511.
      View in: PubMed   Mentions: 10     Fields:    Translation:Cells
    212. Novel role for Na,K-ATPase in phosphatidylinositol 3-kinase signaling and suppression of cell motility. Mol Biol Cell. 2005 Mar; 16(3):1082-94. Barwe SP, Anilkumar G, Moon SY, Zheng Y, Whitelegge JP, Rajasekaran SA, Rajasekaran AK. PMID: 15616195; PMCID: PMC551475.
      View in: PubMed   Mentions: 71     Fields:    Translation:AnimalsCells
    213. ATM protein purified from vaccinia virus expression system: DNA binding requirements for kinase activation. Biochem Biophys Res Commun. 2004 Sep 10; 322(1):74-81. Chun HH, Cary RB, Lansigan F, Whitelegge J, Rawlings DJ, Gatti RA. PMID: 15313175.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCells
    214. Integrating mass spectrometry into membrane protein drug discovery. Curr Opin Drug Discov Devel. 2004 Sep; 7(5):589-99. Weinglass AB, Whitelegge JP, Kaback HR. PMID: 15503862.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimals
    215. Temporal analysis of the antigenic composition of Borrelia burgdorferi during infection in rabbit skin. Infect Immun. 2004 Sep; 72(9):5063-72. Crother TR, Champion CI, Whitelegge JP, Aguilera R, Wu XY, Blanco DR, Miller JN, Lovett MA. PMID: 15321999; PMCID: PMC517453.
      View in: PubMed   Mentions: 49     Fields:    Translation:AnimalsCells
    216. Proline substitutions are not easily accommodated in a membrane protein. J Mol Biol. 2004 Jul 30; 341(1):1-6. Yohannan S, Yang D, Faham S, Boulting G, Whitelegge J, Bowie JU. PMID: 15312757.
      View in: PubMed   Mentions: 32     Fields:    Translation:Cells
    217. Monitoring conformational rearrangements in the substrate-binding site of a membrane transport protein by mass spectrometry. J Biol Chem. 2004 Oct 01; 279(40):41858-65. Weinglass A, Whitelegge JP, Faull KF, Kaback HR. PMID: 15272008.
      View in: PubMed   Mentions: 9     Fields:    Translation:Cells
    218. Sequence of horse (Equus caballus) apoA-II. Another example of a dimer forming apolipoprotein. Comp Biochem Physiol B Biochem Mol Biol. 2004 Jul; 138(3):213-20. Puppione DL, Fischer WH, Park M, Whitelegge JP, Schumaker VN, Golfeiz S, MacDonald MH. PMID: 15253869.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    219. Subtle modification of isotope ratio proteomics; an integrated strategy for expression proteomics. Phytochemistry. 2004 Jun; 65(11):1507-15. Whitelegge JP, Katz JE, Pihakari KA, Hale R, Aguilera R, Gómez SM, Faull KF, Vavilin D, Vermaas W. PMID: 15276448.
      View in: PubMed   Mentions: 12     Fields:    Translation:Cells
    220. Proteome analysis of lipid rafts in Jurkat cells characterizes a raft subset that is involved in NF-kappaB activation. J Proteome Res. 2004 May-Jun; 3(3):445-54. Tu X, Huang A, Bae D, Slaughter N, Whitelegge J, Crother T, Bickel PE, Nel A. PMID: 15253425.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansCells
    221. Inhibition kinetics of carba- and C-fucosyl analogues of GDP-fucose against fucosyltransferase V: implication for the reaction mechanism. Bioorg Med Chem Lett. 2004 Feb 09; 14(3):571-3. Norris AJ, Whitelegge JP, Strouse MJ, Faull KF, Toyokuni T. PMID: 14741245.
      View in: PubMed   Mentions: 1     Fields:    Translation:Cells
    222. The evolution of transmembrane helix kinks and the structural diversity of G protein-coupled receptors. Proc Natl Acad Sci U S A. 2004 Jan 27; 101(4):959-63. Yohannan S, Faham S, Yang D, Whitelegge JP, Bowie JU. PMID: 14732697; PMCID: PMC327124.
      View in: PubMed   Mentions: 83     Fields:    Translation:Cells
    223. Side-chain contributions to membrane protein structure and stability. J Mol Biol. 2004 Jan 02; 335(1):297-305. Faham S, Yang D, Bare E, Yohannan S, Whitelegge JP, Bowie JU. PMID: 14659758.
      View in: PubMed   Mentions: 76     Fields:    Translation:Cells
    224. HPLC and mass spectrometry of intrinsic membrane proteins. Methods Mol Biol. 2004; 251:323-40. Whitelegge JP. PMID: 14704455.
      View in: PubMed   Mentions: 13     Fields:    
    225. Identification of proteins associated with murine gammaherpesvirus 68 virions. J Virol. 2003 Dec; 77(24):13425-32. Bortz E, Whitelegge JP, Jia Q, Zhou ZH, Stewart JP, Wu TT, Sun R. PMID: 14645600; PMCID: PMC296060.
      View in: PubMed   Mentions: 65     Fields:    Translation:HumansAnimalsCells
    226. Transit peptide cleavage sites of integral thylakoid membrane proteins. Mol Cell Proteomics. 2003 Oct; 2(10):1068-85. Gómez SM, Bil' KY, Aguilera R, Nishio JN, Faull KF, Whitelegge JP. PMID: 12902551.
      View in: PubMed   Mentions: 21     Fields:    Translation:AnimalsCells
    227. The flotillins are integral membrane proteins in lipid rafts that contain TCR-associated signaling components: implications for T-cell activation. Clin Immunol. 2003 Aug; 108(2):138-51. Slaughter N, Laux I, Tu X, Whitelegge J, Zhu X, Effros R, Bickel P, Nel A. PMID: 12921760.
      View in: PubMed   Mentions: 26     Fields:    Translation:HumansCells
    228. Proteomic profiling of cancer biomarkers. Brief Funct Genomic Proteomic. 2003 Jul; 2(2):147-58. Shau H, Chandler GS, Whitelegge JP, Gornbein JA, Faull KF, Chang HR. PMID: 15239937.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    229. Characterization of a recombinant molecule covalently indistinguishable from human cerebroside-sulfate activator protein (CSAct or Saposin B). Cell Mol Biol (Noisy-le-grand). 2003 Jul; 49(5):799-807. Whitelegge JP, Ahn V, Norris AJ, Sung H, Waring A, Stevens RL, Fluharty CB, Prive G, Faull KF, Fluharty AL. PMID: 14528917.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimalsCells
    230. Posttranslational hydroxylation of human phenylalanine hydroxylase is a novel example of enzyme self-repair within the second coordination sphere of catalytic iron. J Am Chem Soc. 2003 Apr 23; 125(16):4710-1. Kinzie SD, Thevis M, Ngo K, Whitelegge J, Loo JA, Abu-Omar MM. PMID: 12696880.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    231. Elucidation of substrate binding interactions in a membrane transport protein by mass spectrometry. EMBO J. 2003 Apr 01; 22(7):1467-77. Weinglass AB, Whitelegge JP, Hu Y, Verner GE, Faull KF, Kaback HR. PMID: 12660154; PMCID: PMC152890.
      View in: PubMed   Mentions: 27     Fields:    Translation:Cells
    232. Thylakoid membrane proteomics. Photosynth Res. 2003; 78(3):265-77. Whitelegge JP. PMID: 16245055.
      View in: PubMed   Mentions: 10     Fields:    
    233. Expression, purification, crystallization, and preliminary X-ray analysis of recombinant human saposin B. Protein Expr Purif. 2003 Jan; 27(1):186-93. Ahn VE, Faull KF, Whitelegge JP, Higginson J, Fluharty AL, Privé GG. PMID: 12510003.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCells
    234. Proteomics of membrane proteins. Adv Protein Chem. 2003; 65:271-307. Whitelegge JP, Gómez SM, Faull KF. PMID: 12964373.
      View in: PubMed   Mentions: 6     Fields:    Translation:Cells
    235. Crystal structure of saposin B reveals a dimeric shell for lipid binding. Proc Natl Acad Sci U S A. 2003 Jan 07; 100(1):38-43. Ahn VE, Faull KF, Whitelegge JP, Fluharty AL, Privé GG. PMID: 12518053; PMCID: PMC140876.
      View in: PubMed   Mentions: 64     Fields:    Translation:HumansCells
    236. Identification of the molecular chaperone alpha B-crystallin in demineralized bone powder and osteoblast-like cells. J Orthop Res. 2002 Nov; 20(6):1190-6. Behnam K, Murray SS, Whitelegge JP, Brochmann EJ. PMID: 12472228.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimalsCells
    237. Full subunit coverage liquid chromatography electrospray ionization mass spectrometry (LCMS+) of an oligomeric membrane protein: cytochrome b(6)f complex from spinach and the cyanobacterium Mastigocladus laminosus. Mol Cell Proteomics. 2002 Oct; 1(10):816-27. Whitelegge JP, Zhang H, Aguilera R, Taylor RM, Cramer WA. PMID: 12438564.
      View in: PubMed   Mentions: 58     Fields:    Translation:AnimalsCells
    238. Plant proteomics: BLASTing out of a MudPIT. Proc Natl Acad Sci U S A. 2002 Sep 03; 99(18):11564-6. Whitelegge JP. PMID: 12195024; PMCID: PMC129307.
      View in: PubMed   Mentions: 6     Fields:    Translation:Animals
    239. The chloroplast grana proteome defined by intact mass measurements from liquid chromatography mass spectrometry. Mol Cell Proteomics. 2002 Jan; 1(1):46-59. Gómez SM, Nishio JN, Faull KF, Whitelegge JP. PMID: 12096140.
      View in: PubMed   Mentions: 43     Fields:    Translation:AnimalsCells
    240. Kinetic characterization of enzyme inhibitors using electrospray-ionization mass spectrometry coupled with multiple reaction monitoring. Anal Chem. 2001 Dec 15; 73(24):6024-9. Norris AJ, Whitelegge JP, Faull KF, Toyokuni T. PMID: 11791575.
      View in: PubMed   Mentions:    Fields:    
    241. The chloroplastic GrpE homolog of Chlamydomonas: two isoforms generated by differential splicing. Plant Cell. 2001 Dec; 13(12):2823-39. Schroda M, Vallon O, Whitelegge JP, Beck CF, Wollman FA. PMID: 11752390; PMCID: PMC139491.
      View in: PubMed   Mentions: 51     Fields:    Translation:AnimalsCells
    242. Ferredoxin:NADP+ oxidoreductase is a subunit of the chloroplast cytochrome b6f complex. J Biol Chem. 2001 Oct 12; 276(41):38159-65. Zhang H, Whitelegge JP, Cramer WA. PMID: 11483610.
      View in: PubMed   Mentions: 91     Fields:    Translation:AnimalsCells
    243. Identities of sequestered proteins in aggregates from cells with induced polyglutamine expression. J Cell Biol. 2001 Apr 16; 153(2):283-94. Suhr ST, Senut MC, Whitelegge JP, Faull KF, Cuizon DB, Gage FH. PMID: 11309410; PMCID: PMC2169460.
      View in: PubMed   Mentions: 74     Fields:    Translation:HumansCells
    244. Analysis of enzyme kinetics using electrospray ionization mass spectrometry and multiple reaction monitoring: fucosyltransferase V. Biochemistry. 2001 Apr 03; 40(13):3774-9. Norris AJ, Whitelegge JP, Faull KF, Toyokuni T. PMID: 11300757.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCells
    245. Proteomics. Making sense of genomic information for drug discovery. Am J Pharmacogenomics. 2001; 1(1):29-35. Whitelegge JP, le Coutre J. PMID: 12173311.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    246. Structure of the asparagine-linked sugar chains of porcine kidney and human urine cerebroside sulfate activator protein. J Mass Spectrom. 2000 Dec; 35(12):1416-24. Faull KF, Johnson J, Kim MJ, To T, Whitelegge JP, Stevens RL, Fluharty CB, Fluharty AL. PMID: 11180632.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    247. Methionine oxidation within the cerebroside-sulfate activator protein (CSAct or Saposin B). Protein Sci. 2000 Sep; 9(9):1618-30. Whitelegge JP, Penn B, To T, Johnson J, Waring A, Sherman M, Stevens RL, Fluharty CB, Faull KF, Fluharty AL. PMID: 11045609; PMCID: PMC2144706.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimalsCells
    248. Molecular characterization of Vibrio parahaemolyticus vSGLT: a model for sodium-coupled sugar cotransporters. J Biol Chem. 2000 Aug 18; 275(33):25711-6. Turk E, Kim O, le Coutre J, Whitelegge JP, Eskandari S, Lam JT, Kreman M, Zampighi G, Faull KF, Wright EM. PMID: 10835424.
      View in: PubMed   Mentions: 36     Fields:    Translation:Cells
    249. Proteomics on full-length membrane proteins using mass spectrometry. Biochemistry. 2000 Apr 18; 39(15):4237-42. le Coutre J, Whitelegge JP, Gross A, Turk E, Wright EM, Kaback HR, Faull KF. PMID: 10757971.
      View in: PubMed   Mentions: 29     Fields:    Translation:Cells
    250. Disulfide connectivity in cerebroside sulfate activator is not necessary for biological activity or alpha-helical content but is necessary for trypsin resistance and strong ligand binding. Arch Biochem Biophys. 2000 Apr 15; 376(2):266-74. Faull KF, Higginson J, Waring AJ, Johnson J, To T, Whitelegge JP, Stevens RL, Fluharty CB, Fluharty AL. PMID: 10775412.
      View in: PubMed   Mentions: 6     Fields:    Translation:AnimalsCells
    251. Hydrogen-deuterium exchange signature of porcine cerebroside sulfate activator protein. J Mass Spectrom. 2000 Mar; 35(3):392-401. Faull KF, Higginson J, Waring AJ, To T, Whitelegge JP, Stevens RL, Fluharty CB, Fluharty AL. PMID: 10767769.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    252. Cerebroside sulfate activator protein (Saposin B): chromatographic and electrospray mass spectrometric properties. J Mass Spectrom. 1999 Oct; 34(10):1040-54. Faull KF, Whitelegge JP, Higginson J, To T, Johnson J, Krutchinsky AN, Standing KG, Waring AJ, Stevens RL, Fluharty CB, Fluharty AL. PMID: 10510427.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimalsCells
    253. Toward the bilayer proteome, electrospray ionization-mass spectrometry of large, intact transmembrane proteins. Proc Natl Acad Sci U S A. 1999 Sep 14; 96(19):10695-8. Whitelegge JP, le Coutre J, Lee JC, Engel CK, Privé GG, Faull KF, Kaback HR. PMID: 10485888; PMCID: PMC17945.
      View in: PubMed   Mentions: 34     Fields:    Translation:Cells
    254. Demonstration by mass spectrometry that purified native Treponema pallidum rare outer membrane protein 1 (Tromp1) has a cleaved signal peptide. J Bacteriol. 1999 Aug; 181(16):5094-8. Blanco DR, Whitelegge JP, Miller JN, Lovett MA. PMID: 10438785; PMCID: PMC94002.
      View in: PubMed   Mentions: 2     Fields:    Translation:Cells
    255. Intrinsic membrane association of Drosophila cysteine string proteins. FEBS Lett. 1998 Sep 25; 436(1):85-91. Mastrogiacomo A, Kohan SA, Whitelegge JP, Gundersen CB. PMID: 9771899.
      View in: PubMed   Mentions: 6     Fields:    Translation:AnimalsCells
    256. Electrospray-ionization mass spectrometry of intact intrinsic membrane proteins. Protein Sci. 1998 Jun; 7(6):1423-30. Whitelegge JP, Gundersen CB, Faull KF. PMID: 9655347; PMCID: PMC2144037.
      View in: PubMed   Mentions: 62     Fields:    Translation:AnimalsCells
    257. Assembly of the Photosystem II oxygen-evolving complex is inhibited in psbA site-directed mutants of Chlamydomonas reinhardtii. Aspartate 170 of the D1 polypeptide. J Biol Chem. 1995 Jan 06; 270(1):225-35. Whitelegge JP, Koo D, Diner BA, Domian I, Erickson JM. PMID: 7814379.
      View in: PubMed   Mentions: 7     Fields:    Translation:AnimalsCells
    258. Sequence analysis of photoaffinity-labelled peptides derived by proteolysis of photosystem-2 reaction centres from thylakoid membranes treated with [14C]azidoatrazine. Eur J Biochem. 1992 Aug 01; 207(3):1077-84. Whitelegge JP, Jewess P, Pickering MG, Gerrish C, Camilleri P, Bowyer JR. PMID: 1499553.
      View in: PubMed   Mentions: 8     Fields:    Translation:AnimalsCells
    259. Carboxyl-terminal processing of the D1 protein and photoactivation of water-splitting in photosystem II. Partial purification and characterization of the processing enzyme from Scenedesmus obliquus and Pisum sativum. J Biol Chem. 1992 Mar 15; 267(8):5424-33. Bowyer JR, Packer JC, McCormack BA, Whitelegge JP, Robinson C, Taylor MA. PMID: 1544920.
      View in: PubMed   Mentions: 19     Fields:    Translation:AnimalsCells
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