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Hinman Jason

Title(s)Assistant Professor In-Residence, Neurology
Phone310-825-7802
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    Other Positions
    Title(s)Member, UCLA Stroke Program

    Title(s)Member, UCLA Neurological Rehabilitation and Research Program


    Collapse Research 
    Collapse Research Activities and Funding
    Stroke-Induced Mechanisms of Tau Phosphorylation and Aggregation
    NIH/NINDS R03NS111482Sep 15, 2019 - Jul 31, 2021
    Role: Principal Investigator
    Molecular Mechanisms of Axonal Degeneration After White Matter Stroke
    NIH/NINDS K08NS083740Sep 15, 2013 - Jun 30, 2018
    Role: Principal Investigator

    Collapse Bibliographic 
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Sozmen EG, DiTullio DJ, Rosenzweig S, Hinman JD, Bridges SP, Marin MA, Kawaguchi R, Coppola G, Carmichael ST. White Matter Stroke Induces a Unique Oligo-Astrocyte Niche That Inhibits Recovery. J Neurosci. 2019 Nov 20; 39(47):9343-9359. PMID: 31591156.
      View in: PubMed
    2. Azizkhanian I, Sheth SA, Iavarone AT, Lee S, Kakarla V, Hinman JD. Plasma Lipid Profiling Identifies Biomarkers of Cerebral Microvascular Disease. Front Neurol. 2019; 10:950. PMID: 31555203.
      View in: PubMed
    3. Hayden EY, Putman J, Nunez S, Shin WS, Oberoi M, Charreton M, Dutta S, Li Z, Komuro Y, Joy MT, Bitan G, MacKenzie-Graham A, Jiang L, Hinman JD. Ischemic axonal injury up-regulates MARK4 in cortical neurons and primes tau phosphorylation and aggregation. Acta Neuropathol Commun. 2019 Aug 20; 7(1):135. PMID: 31429800.
      View in: PubMed
    4. Hinman JD. The Power of Observation in Neurology Then and Now-Notes From Charcot's Library. JAMA Neurol. 2019 Jul 29. PMID: 31355864.
      View in: PubMed
    5. Kaneko N, Minhas A, Tateshima S, Colby GP, Szeder V, Hinman JD, Nour M, Jahan R, Duckwiler G. Pre-procedural simulation for precision stent-assisted coiling of cerebral aneurysm. Interv Neuroradiol. 2019 Aug; 25(4):419-422. PMID: 30922200.
      View in: PubMed
    6. Elahi FM, Casaletto KB, Altendahl M, Staffaroni AM, Fletcher E, Filshtein TJ, Glymour MM, Miller BL, Hinman JD, DeCarli C, Goetzl EJ, Kramer JH. "Liquid Biopsy" of White Matter Hyperintensity in Functionally Normal Elders. Front Aging Neurosci. 2018; 10:343. PMID: 30483114.
      View in: PubMed
    7. Bahr Hosseini M, Woolf G, Sharma LK, Hinman JD, Rao NM, Yoo B, Jahan R, Starkman S, Nour M, Raychev R, Liebeskind DS, Saver JL. The Frequency of Substantial Salvageable Penumbra in Thrombectomy-ineligible Patients with Acute Stroke. J Neuroimaging. 2018 11; 28(6):676-682. PMID: 30010229.
      View in: PubMed
    8. Sheth SA, Verma A, Malhotra K, Tang X, Tateshima S, Jahan R, Hinman JD. Human Endothelial Cell Collection from the Middle Cerebral Artery in Acute Ischemic Stroke. J Stroke Cerebrovasc Dis. 2018 Mar; 27(3):669-672. PMID: 29103865.
      View in: PubMed
    9. Coban H, Tung S, Yoo B, Vinters HV, Hinman JD. Molecular Disorganization of Axons Adjacent to Human Cortical Microinfarcts. Front Neurol. 2017; 8:405. PMID: 28861035.
      View in: PubMed
    10. Liebeskind DS, Malhotra K, Hinman JD. Crowdsourcing the Million Brains Initiative-Reply. JAMA Neurol. 2017 08 01; 74(8):1014. PMID: 28604927.
      View in: PubMed
    11. Yu S, Ma SJ, Liebeskind DS, Yu D, Li N, Qiao XJ, Shao X, Yan L, Yoo B, Scalzo F, Hinman JD, Sharma LK, Rao N, Jahan R, Tateshima S, Duckwiler GR, Saver JL, Salamon N, Wang DJ. ASPECTS-based reperfusion status on arterial spin labeling is associated with clinical outcome in acute ischemic stroke patients. J Cereb Blood Flow Metab. 2018 03; 38(3):382-392. PMID: 28266894.
      View in: PubMed
    12. Liebeskind DS, Malhotra K, Hinman JD. Imaging as the Nidus of Precision Cerebrovascular Health: A Million Brains Initiative. JAMA Neurol. 2017 03 01; 74(3):257-258. PMID: 28055073.
      View in: PubMed
    13. Lou X, Yu S, Scalzo F, Starkman S, Ali LK, Kim D, Rao NM, Hinman JD, Vespa PM, Jahan R, Tateshima S, Gonzalez NR, Duckwiler GR, Saver JL, Yoo B, Salamon N, Lyu J, Ma L, Wang DJ, Liebeskind DS. Multi-delay ASL can identify leptomeningeal collateral perfusion in endovascular therapy of ischemic stroke. Oncotarget. 2017 Jan 10; 8(2):2437-2443. PMID: 27974692.
      View in: PubMed
    14. Sozmen EG, Rosenzweig S, Llorente IL, DiTullio DJ, Machnicki M, Vinters HV, Havton LA, Giger RJ, Hinman JD, Carmichael ST. Nogo receptor blockade overcomes remyelination failure after white matter stroke and stimulates functional recovery in aged mice. Proc Natl Acad Sci U S A. 2016 12 27; 113(52):E8453-E8462. PMID: 27956620.
      View in: PubMed
    15. Hinman JD, Rost NS, Leung TW, Montaner J, Muir KW, Brown S, Arenillas JF, Feldmann E, Liebeskind DS. Principles of precision medicine in stroke. J Neurol Neurosurg Psychiatry. 2017 Jan; 88(1):54-61. PMID: 27919057.
      View in: PubMed
    16. Liu D, Scalzo F, Rao NM, Hinman JD, Kim D, Ali LK, Saver JL, Sun W, Dai Q, Liu X, Liebeskind DS. Fluid-Attenuated Inversion Recovery Vascular Hyperintensity Topography, Novel Imaging Marker for Revascularization in Middle Cerebral Artery Occlusion. Stroke. 2016 11; 47(11):2763-2769. PMID: 27659851.
      View in: PubMed
    17. Xiao G, Hinman JD. Concepts and opportunities for repair in cerebral microvascular disease and white matter stroke. Neural Regen Res. 2016 Sep; 11(9):1398-1400. PMID: 27857732.
      View in: PubMed
    18. Brumm AJ, Nunez S, Doroudchi MM, Kawaguchi R, Duan J, Pellegrini M, Lam L, Carmichael ST, Deb A, Hinman JD. Astrocytes Can Adopt Endothelial Cell Fates in a p53-Dependent Manner. Mol Neurobiol. 2017 08; 54(6):4584-4596. PMID: 27389775.
      View in: PubMed
    19. Nunez S, Doroudchi MM, Gleichman AJ, Ng KL, Llorente IL, Sozmen EG, Carmichael ST, Hinman JD. A Versatile Murine Model of Subcortical White Matter Stroke for the Study of Axonal Degeneration and White Matter Neurobiology. J Vis Exp. 2016 Mar 17; (109). PMID: 27023377.
      View in: PubMed
    20. Liu D, Scalzo F, Starkman S, Rao NM, Hinman JD, Kim D, Ali LK, Saver JL, Noorian AR, Ng K, Liang C, Sheth SA, Yoo B, Liu X, Liebeskind DS. DWI Lesion Patterns Predict Outcome in Stroke Patients with Thrombolysis. Cerebrovasc Dis. 2015; 40(5-6):279-285. PMID: 26513397.
      View in: PubMed
    21. Tansy AP, Hinman JD, Ng KL, Calderon-Arnulphi M, Modir R, Chatfield F, Liebeskind DS. Image More to Save More. Front Neurol. 2015; 6:156. PMID: 26217302.
      View in: PubMed
    22. Hinman JD, Lee MD, Tung S, Vinters HV, Carmichael ST. Molecular disorganization of axons adjacent to human lacunar infarcts. Brain. 2015 Mar; 138(Pt 3):736-45. PMID: 25614025.
      View in: PubMed
    23. Hinman JD. The back and forth of axonal injury and repair after stroke. Curr Opin Neurol. 2014 Dec; 27(6):615-23. PMID: 25364952.
      View in: PubMed
    24. Takahashi C, Liang CW, Liebeskind DS, Hinman JD. To Tube or Not to Tube? The Role of Intubation during Stroke Thrombectomy. Front Neurol. 2014; 5:170. PMID: 25295027.
      View in: PubMed
    25. Hinman JD, Rao NM, Yallapragada A, Capri J, Souda P, Whitelegge J, Yong WH, Jahan R, Quinones-Baldrich W, Saver JL. Drip, Ship, and Grip, then Slice and Dice: Comprehensive Stroke Center Management of Cervical and Intracranial Emboli. Front Neurol. 2013; 4:104. PMID: 23908644.
      View in: PubMed
    26. Chen CD, Sloane JA, Li H, Aytan N, Giannaris EL, Zeldich E, Hinman JD, Dedeoglu A, Rosene DL, Bansal R, Luebke JI, Kuro-o M, Abraham CR. The antiaging protein Klotho enhances oligodendrocyte maturation and myelination of the CNS. J Neurosci. 2013 Jan 30; 33(5):1927-39. PMID: 23365232.
      View in: PubMed
    27. Hinman JD, Rasband MN, Carmichael ST. Remodeling of the axon initial segment after focal cortical and white matter stroke. Stroke. 2013 Jan; 44(1):182-9. PMID: 23233385.
      View in: PubMed
    28. Sozmen EG, Hinman JD, Carmichael ST. Models that matter: white matter stroke models. Neurotherapeutics. 2012 Apr; 9(2):349-58. PMID: 22362423.
      View in: PubMed
    29. Hinman JD, Chen CD, Oh SY, Hollander W, Abraham CR. Age-dependent accumulation of ubiquitinated 2',3'-cyclic nucleotide 3'-phosphodiesterase in myelin lipid rafts. Glia. 2008 Jan 01; 56(1):118-33. PMID: 17963267.
      View in: PubMed
    30. Hinman JD, Abraham CR. What's behind the decline? The role of white matter in brain aging. Neurochem Res. 2007 Dec; 32(12):2023-31. PMID: 17447140.
      View in: PubMed
    31. Hinman JD, Peters A, Cabral H, Rosene DL, Hollander W, Rasband MN, Abraham CR. Age-related molecular reorganization at the node of Ranvier. J Comp Neurol. 2006 Apr 01; 495(4):351-62. PMID: 16485288.
      View in: PubMed
    32. Chen CD, Oh SY, Hinman JD, Abraham CR. Visualization of APP dimerization and APP-Notch2 heterodimerization in living cells using bimolecular fluorescence complementation. J Neurochem. 2006 Apr; 97(1):30-43. PMID: 16515557.
      View in: PubMed
    33. Oh SY, Ellenstein A, Chen CD, Hinman JD, Berg EA, Costello CE, Yamin R, Neve RL, Abraham CR. Amyloid precursor protein interacts with notch receptors. J Neurosci Res. 2005 Oct 01; 82(1):32-42. PMID: 16118793.
      View in: PubMed
    34. Hinman JD, Duce JA, Siman RA, Hollander W, Abraham CR. Activation of calpain-1 in myelin and microglia in the white matter of the aged rhesus monkey. J Neurochem. 2004 Apr; 89(2):430-41. PMID: 15056286.
      View in: PubMed
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