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Jason D Hinman

Title(s)Assistant Professor-in-Residence, Neurology
SchoolMedicine
Address710 Westwood Plaza C109
Los Angeles CA 90024
Phone56761
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    Collapse Research 
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    Molecular and Cellular Pathways Regulating Neurovascular Dysfunction in Degenerative Tauopathies
    NIH R56AG069115Sep 30, 2020 - Aug 31, 2021
    Role: Co-Principal Investigator
    Mechanisms for vascular regulation of remyelination in white matter injury
    NIH RF1NS114336Apr 15, 2020 - Mar 31, 2025
    Role: Principal Investigator
    Shear Stress and Endothelial Pathophysiology in Intracranial Atherosclerosis
    NIH R01NS112799Feb 1, 2020 - Jan 31, 2025
    Role: Co-Principal Investigator
    Stroke-Induced Mechanisms of Tau Phosphorylation and Aggregation
    NIH R03NS111482Sep 15, 2019 - Jul 31, 2021
    Role: Principal Investigator
    Molecular Mechanisms of Axonal Degeneration After White Matter Stroke
    NIH K08NS083740Sep 15, 2013 - Dec 31, 2018
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Endothelial Shear Stress and Platelet Fc?RIIa Expression in Intracranial Atherosclerotic Disease. Front Neurol. 2021; 12:646309. Liebeskind DS, Hinman JD, Kaneko N, Kitajima H, Honda T, De Havenon AH, Feldmann E, Nogueira RG, Prabhakaran S, Romano JG, Callas PW, Schneider DJ. PMID: 33716947.
      View in: PubMed   Mentions:
    2. miR-142-3p Regulates Cortical Oligodendrocyte Gene Co-expression Networks Associated with Tauopathy. Hum Mol Genet. 2021 Feb 08. Hinman JD, Ngo KJ, Kim D, Chen C, Abraham CR, Ghanbari M, Ikram MA, Kushner SA, Kawaguchi R, Coppola G, Goth K, Bellusci S, Hernandez I, Kosik KS, Fogel BL. PMID: 33555315.
      View in: PubMed   Mentions:    Fields:    
    3. Impact of eloquent motor cortex-tissue reperfusion beyond the traditional thrombolysis in cerebral infarction (TICI) scoring after thrombectomy. J Neurointerv Surg. 2020 Dec 18. Raychev R, Saber H, Saver JL, Hinman JD, Brown S, Vinuela F, Duckwiler G, Jahan R, Tateshima S, Szeder V, Nour M, Colby GP, Restrepo L, Kim D, Bahr-Hosseini M, Ali L, Starkman S, Rao N, Nogueira RG, Liebeskind D. PMID: 33443113.
      View in: PubMed   Mentions:    Fields:    
    4. Flow-Mediated Susceptibility and Molecular Response of Cerebral Endothelia to SARS-CoV-2 Infection. Stroke. 2020 Nov 09; STROKEAHA120032764. Kaneko N, Satta S, Komuro Y, Muthukrishnan SD, Kakarla V, Guo L, An J, Elahi F, Kornblum HI, Liebeskind DS, Hsiai T, Hinman JD. PMID: 33161843.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    5. Encephaloduroarteriosynangiosis (EDAS) revascularization for symptomatic intracranial atherosclerotic steno-occlusive (ERSIAS) Phase-II objective performance criterion trial. Int J Stroke. 2020 Oct 29; 1747493020967256. Gonzalez NR, Jiang H, Lyden P, Song S, Schlick K, Dumitrascu O, Quintero-Consuegra MD, Toscano JF, Liebeskind DS, Restrepo L, Rao N, Hinman J, Alexander MJ, Schievink W, Piantadosi S, Saver JL. PMID: 33115382.
      View in: PubMed   Mentions:    Fields:    
    6. Efficient Multimodal MRI Evaluation for Endovascular Thrombectomy of Anterior Circulation Large Vessel Occlusion. J Stroke Cerebrovasc Dis. 2020 Dec; 29(12):105271. Atchaneeyasakul K, Liebeskind DS, Jahan R, Starkman S, Sharma L, Yoo B, Avelar J, Rao N, Hinman J, Duckwiler G, Nour M, Szeder V, Tateshima S, Colby G, Hosseini MB, Raychev R, Kim D, Saver JL. PMID: 32992192.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    7. In Vitro Modeling of Human Brain Arteriovenous Malformation for Endovascular Simulation and Flow Analysis. World Neurosurg. 2020 09; 141:e873-e879. Kaneko N, Ullman H, Ali F, Berg P, Ooi YC, Tateshima S, Colby GP, Komuro Y, Hu P, Khatibi K, Ponce Mejia LL, Szeder V, Nour M, Guo L, Chien A, Vinuela F, Nemoto S, Mashiko T, Sehara Y, Hinman JD, Duckwiler G, Jahan R. PMID: 32565379.
      View in: PubMed   Mentions:    Fields:    
    8. Modeling Mixed Vascular and Alzheimer's Dementia Using Focal Subcortical Ischemic Stroke in Human ApoE4-TR:5XFAD Transgenic Mice. Transl Stroke Res. 2020 10; 11(5):1064-1076. Hayden EY, Huang JM, Charreton M, Nunez SM, Putman JN, Teter B, Lee JT, Welch A, Frautschy S, Cole G, Teng E, Hinman JD. PMID: 32086779.
      View in: PubMed   Mentions:    Fields:    
    9. White Matter Stroke Induces a Unique Oligo-Astrocyte Niche That Inhibits Recovery. J Neurosci. 2019 11 20; 39(47):9343-9359. Sozmen EG, DiTullio DJ, Rosenzweig S, Hinman JD, Bridges SP, Marin MA, Kawaguchi R, Coppola G, Carmichael ST. PMID: 31591156.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimalsCells
    10. Ischemic axonal injury up-regulates MARK4 in cortical neurons and primes tau phosphorylation and aggregation. Acta Neuropathol Commun. 2019 08 20; 7(1):135. Hayden EY, Putman J, Nunez S, Shin WS, Oberoi M, Charreton M, Dutta S, Li Z, Komuro Y, Joy MT, Bitan G, MacKenzie-Graham A, Jiang L, Hinman JD. PMID: 31429800.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    11. The Power of Observation in Neurology Then and Now-Notes From Charcot's Library. JAMA Neurol. 2019 Jul 29. Hinman JD. PMID: 31355864.
      View in: PubMed   Mentions:    Fields:    
    12. Pre-procedural simulation for precision stent-assisted coiling of cerebral aneurysm. Interv Neuroradiol. 2019 Aug; 25(4):419-422. Kaneko N, Minhas A, Tateshima S, Colby GP, Szeder V, Hinman JD, Nour M, Jahan R, Duckwiler G. PMID: 30922200.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    13. The Frequency of Substantial Salvageable Penumbra in Thrombectomy-ineligible Patients with Acute Stroke. J Neuroimaging. 2018 11; 28(6):676-682. Bahr Hosseini M, Woolf G, Sharma LK, Hinman JD, Rao NM, Yoo B, Jahan R, Starkman S, Nour M, Raychev R, Liebeskind DS, Saver JL. PMID: 30010229.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    14. Molecular Disorganization of Axons Adjacent to Human Cortical Microinfarcts. Front Neurol. 2017; 8:405. Coban H, Tung S, Yoo B, Vinters HV, Hinman JD. PMID: 28861035.
      View in: PubMed   Mentions:
    15. ASPECTS-based reperfusion status on arterial spin labeling is associated with clinical outcome in acute ischemic stroke patients. J Cereb Blood Flow Metab. 2018 03; 38(3):382-392. Yu S, Ma SJ, Liebeskind DS, Yu D, Li N, Qiao XJ, Shao X, Yan L, Yoo B, Scalzo F, Hinman JD, Sharma LK, Rao N, Jahan R, Tateshima S, Duckwiler GR, Saver JL, Salamon N, Wang DJ. PMID: 28266894.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    16. Imaging as the Nidus of Precision Cerebrovascular Health: A Million Brains Initiative. JAMA Neurol. 2017 03 01; 74(3):257-258. Liebeskind DS, Malhotra K, Hinman JD. PMID: 28055073.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    17. Nogo receptor blockade overcomes remyelination failure after white matter stroke and stimulates functional recovery in aged mice. Proc Natl Acad Sci U S A. 2016 12 27; 113(52):E8453-E8462. Sozmen EG, Rosenzweig S, Llorente IL, DiTullio DJ, Machnicki M, Vinters HV, Havton LA, Giger RJ, Hinman JD, Carmichael ST. PMID: 27956620.
      View in: PubMed   Mentions: 27     Fields:    Translation:HumansAnimalsCells
    18. Principles of precision medicine in stroke. J Neurol Neurosurg Psychiatry. 2017 Jan; 88(1):54-61. Hinman JD, Rost NS, Leung TW, Montaner J, Muir KW, Brown S, Arenillas JF, Feldmann E, Liebeskind DS. PMID: 27919057.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    19. Fluid-Attenuated Inversion Recovery Vascular Hyperintensity Topography, Novel Imaging Marker for Revascularization in Middle Cerebral Artery Occlusion. Stroke. 2016 11; 47(11):2763-2769. Liu D, Scalzo F, Rao NM, Hinman JD, Kim D, Ali LK, Saver JL, Sun W, Dai Q, Liu X, Liebeskind DS. PMID: 27659851.
      View in: PubMed   Mentions: 10     Fields:    Translation:Humans
    20. Concepts and opportunities for repair in cerebral microvascular disease and white matter stroke. Neural Regen Res. 2016 Sep; 11(9):1398-1400. Xiao G, Hinman JD. PMID: 27857732.
      View in: PubMed   Mentions:
    21. Astrocytes Can Adopt Endothelial Cell Fates in a p53-Dependent Manner. Mol Neurobiol. 2017 08; 54(6):4584-4596. Brumm AJ, Nunez S, Doroudchi MM, Kawaguchi R, Duan J, Pellegrini M, Lam L, Carmichael ST, Deb A, Hinman JD. PMID: 27389775.
      View in: PubMed   Mentions: 4     Fields:    Translation:AnimalsCells
    22. A Versatile Murine Model of Subcortical White Matter Stroke for the Study of Axonal Degeneration and White Matter Neurobiology. J Vis Exp. 2016 Mar 17; (109). Nunez S, Doroudchi MM, Gleichman AJ, Ng KL, Llorente IL, Sozmen EG, Carmichael ST, Hinman JD. PMID: 27023377.
      View in: PubMed   Mentions: 5     Fields:    Translation:AnimalsCells
    23. Molecular disorganization of axons adjacent to human lacunar infarcts. Brain. 2015 Mar; 138(Pt 3):736-45. Hinman JD, Lee MD, Tung S, Vinters HV, Carmichael ST. PMID: 25614025.
      View in: PubMed   Mentions: 22     Fields:    Translation:HumansCells
    24. The back and forth of axonal injury and repair after stroke. Curr Opin Neurol. 2014 Dec; 27(6):615-23. Hinman JD. PMID: 25364952.
      View in: PubMed   Mentions: 25     Fields:    Translation:HumansAnimalsCells
    25. Drip, Ship, and Grip, then Slice and Dice: Comprehensive Stroke Center Management of Cervical and Intracranial Emboli. Front Neurol. 2013; 4:104. Hinman JD, Rao NM, Yallapragada A, Capri J, Souda P, Whitelegge J, Yong WH, Jahan R, Quinones-Baldrich W, Saver JL. PMID: 23908644.
      View in: PubMed   Mentions:
    26. The antiaging protein Klotho enhances oligodendrocyte maturation and myelination of the CNS. J Neurosci. 2013 Jan 30; 33(5):1927-39. Chen CD, Sloane JA, Li H, Aytan N, Giannaris EL, Zeldich E, Hinman JD, Dedeoglu A, Rosene DL, Bansal R, Luebke JI, Kuro-o M, Abraham CR. PMID: 23365232.
      View in: PubMed   Mentions: 53     Fields:    Translation:AnimalsCells
    27. Remodeling of the axon initial segment after focal cortical and white matter stroke. Stroke. 2013 Jan; 44(1):182-9. Hinman JD, Rasband MN, Carmichael ST. PMID: 23233385.
      View in: PubMed   Mentions: 41     Fields:    Translation:AnimalsCells
    28. Models that matter: white matter stroke models. Neurotherapeutics. 2012 Apr; 9(2):349-58. Sozmen EG, Hinman JD, Carmichael ST. PMID: 22362423.
      View in: PubMed   Mentions: 32     Fields:    Translation:HumansAnimalsCells
    29. Age-related molecular reorganization at the node of Ranvier. J Comp Neurol. 2006 Apr 01; 495(4):351-62. Hinman JD, Peters A, Cabral H, Rosene DL, Hollander W, Rasband MN, Abraham CR. PMID: 16485288.
      View in: PubMed   Mentions: 35     Fields:    Translation:AnimalsCells
    30. Activation of calpain-1 in myelin and microglia in the white matter of the aged rhesus monkey. J Neurochem. 2004 Apr; 89(2):430-41. Hinman JD, Duce JA, Siman RA, Hollander W, Abraham CR. PMID: 15056286.
      View in: PubMed   Mentions: 10     Fields:    Translation:AnimalsCells
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