Tzung Hsiai

Title(s)Professor-in-Residence, Medicine
SchoolMedicine
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    Tzung Hsiai, Ph.D., previously held the Maud Cady Guthman Chair in Cardiology (7/1/2018 - 6/30/2023).

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    Integrating Volumetric Light-Field with Computational Fluid Dynamics to Study Myocardial Trabeculation and Function
    NIH R01HL159970Aug 1, 2021 - May 31, 2025
    Role: Principal Investigator
    Caltech/UCLA Individualized Theranostic Engineering to Advance Metabolic System (iTEAM)
    NIH T32EB027629Jul 8, 2020 - Jun 30, 2025
    Role: Principal Investigator
    UCLA and Caltech integrated Cardiovascular Medicine for Bioengineers (iCMB)
    NIH T32HL144449Jul 1, 2020 - Jun 30, 2025
    Role: Principal Investigator
    Intravascular Deployment of a Wirelessly Powered Micro-Pacer
    NIH R01HL149808Feb 5, 2020 - Jan 31, 2024
    Role: Principal Investigator
    Exercise-Induced Shear Stress Modulates Metabolic Pathways for Vascular Repair and Protection
    NIH I01BX004356Jan 1, 2019 - Dec 31, 2022
    Role: Principal Investigator
    Role of Intestinal Microbiota in Dyslipidemia and Atherosclerosis Induced by Ambient Ultrafine Particles
    NIH R01ES029395Sep 30, 2018 - Aug 31, 2023
    Role: Co-Principal Investigator
    Shear Stress and Light-Sheets to Study Cardiac Trabeculation
    NIH R01HL129727Jul 9, 2015 - Dec 31, 2024
    Role: Principal Investigator
    Electrochemical Impedance Spectroscopy to Assess Metabolically Active Plaque
    NIH R01HL118650Jul 10, 2014 - Mar 31, 2023
    Role: Principal Investigator
    Micro-Sensors to Study Electrical and Mechanical Coupling of Injured Myocardium
    NIH R01HL111437Mar 1, 2012 - Mar 31, 2021
    Role: Principal Investigator
    Shear Stress and Mechnaically Unstable Plaque
    NIH R21HL091302Jul 1, 2009 - Jun 30, 2012
    Role: Principal Investigator
    Linking Spatial Variations in Shear Stress with Oxidation Stress
    NIH R01HL083015Jan 1, 2006 - May 31, 2018
    Role: Principal Investigator
    Microsensors to Study Endothelial Cell Dynamics
    NIH K08HL068689Jan 1, 2003 - Dec 31, 2008
    Role: Principal Investigator
    OXIDATIVE AND ATHEROGENIC ACTION OF IN VIVO MODIFIED LDL
    NIH R01HL050350Aug 1, 1995 - May 31, 2006
    Role: Principal Investigator

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    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Imaging-guided deep tissue in vivo sound printing. Science. 2025 May 08; 388(6747):616-623. Davoodi E, Li J, Ma X, Najafabadi AH, Yoo J, Lu G, Sani ES, Lee S, Montazerian H, Kim G, Williams J, Yang JW, Zeng Y, Li LS, Jin Z, Sadri B, Nia SS, Wang LV, Hsiai TK, Weiss PS, Zhou Q, Khademhosseini A, Wu D, Shapiro MG, Gao W. PMID: 40339009.
      View in: PubMed   Mentions:    Fields:    Translation:Animals
    2. PIEZO1 Activation-Mediated Generation of Transgene-Free Long-Term Hematopoietic Stem Cells. Am J Hematol. 2025 Jun; 100(6):963-979. Scapin G, Cillis JL, Goulard MC, Patch TC, Gomez Limia CE, Ding Y, Du W, Dharampuriya PR, Hagedorn EJ, Anderson H, Musso GA, Curley CR, Teets EM, MacRae CA, Sehgal L, Hsiai TK, Blaser BW, Shah DI. PMID: 40320799.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    3. Habitual Exercise Modulates Neuroimmune Interaction to Mitigate Aortic Stiffness. Circ Res. 2025 Apr 30. Cho JM, Vu K, Park SK, Zhu E, Li YR, Zhao P, Yokota T, Yang L, Lu R, Xiang YK, Shen YH, Chapleau MW, Hsiai TK. PMID: 40304034.
      View in: PubMed   Mentions:    Fields:    
    4. Boosting hydrogel conductivity via water-dispersible conducting polymers for injectable bioelectronics. Nat Commun. 2025 Apr 22; 16(1):3755. Montazerian H, Davoodi E, Wang C, Lorestani F, Li J, Haghniaz R, Sampath RR, Mohaghegh N, Khosravi S, Zehtabi F, Zhao Y, Hosseinzadeh N, Liu T, Hsiai TK, Najafabadi AH, Langer R, Anderson DG, Weiss PS, Khademhosseini A, Gao W. PMID: 40263282; PMCID: PMC12015517.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimals
    5. Author Correction: Viscoelastic synthetic antigen-presenting cells for augmenting the potency of cancer therapies. Nat Biomed Eng. 2025 Apr 15. Liu Z, Li YR, Yang Y, Zhu Y, Yuan W, Hoffman T, Wu Y, Zhu E, Zarubova J, Shen J, Nan H, Yeh KW, Hasani-Sadrabadi MM, Zhu Y, Fang Y, Ge X, Li Z, Soto J, Hsiai T, Yang L, Li S. PMID: 40234704.
      View in: PubMed   Mentions:    Fields:    
    6. Engineering an in vivo charging station for CAR-redirected invariant natural killer T cells to enhance cancer therapy. Res Sq. 2025 Apr 10. Li S, Li YR, Nan H, Liu Z, Fang Y, Zhu Y, Lyu Z, Shao Z, Zhu E, Zhang B, Yang Y, Shen X, Chen Y, Hsiai T, Yang L. PMID: 40297706; PMCID: PMC12036460.
      View in: PubMed   Mentions:
    7. Demonstration and structural basis of a therapeutic DNA aptamer for SARS-CoV-2 spike protein detection. bioRxiv. 2025 Mar 17. Liu Y, Wang K, Wang W, Kashyap S, Jih J, Imani A, Hsiai T, Zhou ZH. PMID: 40166151; PMCID: PMC11957045.
      View in: PubMed   Mentions:
    8. Printable molecule-selective core-shell nanoparticles for wearable and implantable sensing. Nat Mater. 2025 Apr; 24(4):589-598. Wang M, Ye C, Yang Y, Mukasa D, Wang C, Xu C, Min J, Solomon SA, Tu J, Shen G, Tang S, Hsiai TK, Li Z, McCune JS, Gao W. PMID: 39900737.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    9. Allogeneic CD33-directed CAR-NKT cells for the treatment of bone marrow-resident myeloid malignancies. Nat Commun. 2025 Feb 01; 16(1):1248. Li YR, Fang Y, Niu S, Zhu Y, Chen Y, Lyu Z, Zhu E, Tian Y, Huang J, Rezek V, Kitchen S, Hsiai T, Zhou JJ, Wang P, Chai-Ho W, Park S, Seet CS, Oliai C, Yang L. PMID: 39893165; PMCID: PMC11787387.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimals
    10. Rapid prediction of acute thrombosis via nanoengineered immunosensors with unsupervised clustering for multiple circulating biomarkers. Sci Adv. 2024 Dec 13; 10(50):eadq6778. Wang K, Wang S, Margolis S, Cho JM, Zhu E, Dupuy A, Yin J, Park SK, Magyar CE, Adeyiga OB, Jensen KS, Belperio JA, Passam F, Zhao P, Hsiai TK. PMID: 39661669; PMCID: PMC11633740.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    11. Viscoelastic synthetic antigen-presenting cells for augmenting the potency of cancer therapies. Nat Biomed Eng. 2024 Dec; 8(12):1615-1633. Liu Z, Li YR, Yang Y, Zhu Y, Yuan W, Hoffman T, Wu Y, Zhu E, Zarubova J, Shen J, Nan H, Yeh KW, Hasani-Sadrabadi MM, Zhu Y, Fang Y, Ge X, Li Z, Soto J, Hsiai T, Yang L, Li S. PMID: 39455719.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    12. Kilohertz volumetric imaging of in-vivo dynamics using squeezed light field microscopy. bioRxiv. 2024 Oct 14. Wang Z, Zhao R, Wagenaar DA, Espino D, Sheintuch L, Benshlomo O, Kang W, Lee C, Schmidt W, Pammar A, Zhu E, Wang J, Wong GCL, Liang R, Golshani P, Hsiai T, Gao L. PMID: 38585760; PMCID: PMC10996549.
      View in: PubMed   Mentions:
    13. Biomimetic cell stimulation with a graphene oxide antigen-presenting platform for developing T cell-based therapies. Nat Nanotechnol. 2024 Dec; 19(12):1914-1922. Zhu E, Yu J, Li YR, Ma F, Wang YC, Liu Y, Li M, Kim YJ, Zhu Y, Hahn Z, Zhou Y, Brown J, Zhang Y, Pelegrini M, Hsiai T, Yang L, Huang Y. PMID: 39313679.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    14. Frontiers in artificial intelligence-directed light-sheet microscopy for uncovering biological phenomena and multi-organ imaging. View (Beijing). 2024 Oct; 5(5). Zhu E, Li YR, Margolis S, Wang J, Wang K, Zhang Y, Wang S, Park J, Zheng C, Yang L, Chu A, Zhang Y, Gao L, Hsiai TK. PMID: 39478956; PMCID: PMC11521201.
      View in: PubMed   Mentions: 1  
    15. Development of a Machine Learning-Enabled Virtual Reality Tool for Preoperative Planning of Functional Endoscopic Sinus Surgery. J Neurol Surg Rep. 2024 Jul; 85(3):e118-e123. Gudapati V, Chen A, Meyer S, Jay Kuo CC, Ding Y, Hsiai TK, Wang M. PMID: 39104747; PMCID: PMC11300101.
      View in: PubMed   Mentions:
    16. Ambient Particulate Matter Induces In Vitro Toxicity to Intestinal Epithelial Cells without Exacerbating Acute Colitis Induced by Dextran Sodium Sulfate or 2,4,6-Trinitrobenzenesulfonic Acid. Int J Mol Sci. 2024 Jun 29; 25(13). Chang C, Louie A, Zhou Y, Gupta R, Liang F, Xanthou G, Ereso J, Koletic C, Yang JC, Sedighian F, Lagishetty V, Arias-Jayo N, Altuwayjiri A, Tohidi R, Navab M, Reddy ST, Sioutas C, Hsiai T, Araujo JA, Jacobs JP. PMID: 39000289; PMCID: PMC11241079.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    17. Non-Invasive Detection of Early-Stage Fatty Liver Disease via an On-Skin Impedance Sensor and Attention-Based Deep Learning. Adv Sci (Weinh). 2024 Aug; 11(31):e2400596. Wang K, Margolis S, Cho JM, Wang S, Arianpour B, Jabalera A, Yin J, Hong W, Zhang Y, Zhao P, Zhu E, Reddy S, Hsiai TK. PMID: 38887178; PMCID: PMC11336938.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimals
    18. Engineering allorejection-resistant CAR-NKT cells from hematopoietic stem cells for off-the-shelf cancer immunotherapy. Mol Ther. 2024 Jun 05; 32(6):1849-1874. Li YR, Zhou Y, Yu J, Zhu Y, Lee D, Zhu E, Li Z, Kim YJ, Zhou K, Fang Y, Lyu Z, Chen Y, Tian Y, Huang J, Cen X, Husman T, Cho JM, Hsiai T, Zhou JJ, Wang P, Puliafito BR, Larson SM, Yang L. PMID: 38584391; PMCID: PMC11184334.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansAnimalsCells
    19. Hemodynamic regulation allows stable growth of microvascular networks. Proc Natl Acad Sci U S A. 2024 Feb 27; 121(9):e2310993121. Qi Y, Chang SS, Wang Y, Chen C, Baek KI, Hsiai T, Roper M. PMID: 38386707; PMCID: PMC10907248.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    20. A PARYLENE-BASED MEMS INTRAVASCULAR IMPLANT FOR WIRELESS CARDIAC PACING. Proc IEEE Int Conf Micro Electro Mech Syst. 2024 Jan; 2024:437-440. Shang KM, Hsiai T, Tai YC. PMID: 40321474; PMCID: PMC12047634.
      View in: PubMed   Mentions:
    21. Harnessing Biomaterials to Amplify Immunity in Aged Mice through T Memory Stem Cells. ACS Nano. 2024 03 05; 18(9):6908-6926. Hasani-Sadrabadi MM, Majedi FS, Zarubova J, Thauland TJ, Arumugaswami V, Hsiai TK, Bouchard LS, Butte MJ, Li S. PMID: 38381620.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    22. Exercise mitigates flow recirculation and activates metabolic transducer SCD1 to catalyze vascular protective metabolites. Sci Adv. 2024 Feb 16; 10(7):eadj7481. Cavallero S, Roustaei M, Satta S, Cho JM, Phan H, Baek KI, Blázquez-Medela AM, Gonzalez-Ramos S, Vu K, Park SK, Yokota T, Sumner J, Mack JJ, Sigmund CD, Reddy ST, Li R, Hsiai TK. PMID: 38354249; PMCID: PMC10866565.
      View in: PubMed   Mentions: 2     Fields:    Translation:Animals
    23. A physicochemical-sensing electronic skin for stress response monitoring. Nat Electron. 2024 Feb; 7(2):168-179. Xu C, Song Y, Sempionatto JR, Solomon SA, Yu Y, Nyein HYY, Tay RY, Li J, Heng W, Min J, Lao A, Hsiai TK, Sumner JA, Gao W. PMID: 38433871; PMCID: PMC10906959.
      View in: PubMed   Mentions: 26  
    24. A Modular Framework for Implicit 3D-0D Coupling in Cardiac Mechanics. Comput Methods Appl Mech Eng. 2024 Mar 01; 421. Brown AL, Salvador M, Shi L, Pfaller MR, Hu Z, Harold KE, Hsiai T, Vedula V, Marsden AL. PMID: 38523716; PMCID: PMC10956732.
      View in: PubMed   Mentions:
    25. Subchronic inhalation exposure to ultrafine particulate matter alters the intestinal microbiome in various mouse models. Environ Res. 2024 May 01; 248:118242. Chang C, Gupta R, Sedighian F, Louie A, Gonzalez DM, Le C, Cho JM, Park SK, Castellanos J, Ting TW, Dong TS, Arias-Jayo N, Lagishetty V, Navab M, Reddy S, Sioutas C, Hsiai T, Jacobs JP, Araujo JA. PMID: 38242419; PMCID: PMC11737635.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsPHPublic Health
    26. Machine learning-directed electrical impedance tomography to predict metabolically vulnerable plaques. Bioeng Transl Med. 2024 Jan; 9(1):e10616. Chen J, Wang S, Wang K, Abiri P, Huang ZY, Yin J, Jabalera AM, Arianpour B, Roustaei M, Zhu E, Zhao P, Cavallero S, Duarte-Vogel S, Stark E, Luo Y, Benharash P, Tai YC, Cui Q, Hsiai TK. PMID: 38193119; PMCID: PMC10771559.
      View in: PubMed   Mentions: 6  
    27. A self-assembled implantable microtubular pacemaker for wireless cardiac electrotherapy. Sci Adv. 2023 10 20; 9(42):eadj0540. Wang S, Cui Q, Abiri P, Roustaei M, Zhu E, Li YR, Wang K, Duarte S, Yang L, Ebrahimi R, Bersohn M, Chen J, Hsiai TK. PMID: 37851816; PMCID: PMC10584332.
      View in: PubMed   Mentions: 3     Fields:    Translation:Animals
    28. Integrating 4-D light-sheet fluorescence microscopy and genetic zebrafish system to investigate ambient pollutants-mediated toxicity. Sci Total Environ. 2023 Dec 01; 902:165947. Gonzalez-Ramos S, Wang J, Cho JM, Zhu E, Park SK, In JG, Reddy ST, Castillo EF, Campen MJ, Hsiai TK. PMID: 37543337; PMCID: PMC10659062.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsPHPublic Health
    29. Microfluidic Organ-Chips and Stem Cell Models in the Fight Against COVID-19. Circ Res. 2023 05 12; 132(10):1405-1424. Satta S, Rockwood SJ, Wang K, Wang S, Mozneb M, Arzt M, Hsiai TK, Sharma A. PMID: 37167356; PMCID: PMC10171291.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
    30. Exercise Mitigates Flow Recirculation and Activates Mechanosensitive Transcriptome to Uncover Endothelial SCD1-Catalyzed Anti-Inflammatory Metabolites. bioRxiv. 2023 May 03. Cavallero S, Roustaei M, Satta S, Cho JM, Phan H, Baek KI, Blázquez-Medela AM, Gonzalez-Ramos S, Vu K, Park SK, Yokota T, Sumner JA, Mack JJ, Sigmund CD, Reddy ST, Li R, Hsiai TK. PMID: 37205360; PMCID: PMC10187200.
      View in: PubMed   Mentions:
    31. Engineering organ-on-a-chip systems to model viral infections. Biofabrication. 2023 02 06; 15(2). Shahabipour F, Satta S, Mahmoodi M, Sun A, de Barros NR, Li S, Hsiai T, Ashammakhi N. PMID: 35390777; PMCID: PMC9883621.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansAnimals
    32. Augmented light field tomography through parallel spectral encoding. Optica. 2023 Jan 20; 10(1):62-65. Wang Z, Hsiai TK, Gao L. PMID: 37323823; PMCID: PMC10270672.
      View in: PubMed   Mentions:
    33. Non-invasive photoacoustic computed tomography of rat heart anatomy and function. Light Sci Appl. 2023 Jan 03; 12(1):12. Lin L, Tong X, Cavallero S, Zhang Y, Na S, Cao R, Hsiai TK, Wang LV. PMID: 36593252; PMCID: PMC9807634.
      View in: PubMed   Mentions: 6  
    34. Quantitative 4D imaging of biomechanical regulation of ventricular growth and maturation. Curr Opin Biomed Eng. 2023 Jun; 26. Cho JM, Poon MLS, Zhu E, Wang J, Butcher JT, Hsiai T. PMID: 37424697; PMCID: PMC10327868.
      View in: PubMed   Mentions: 2  
    35. Recent advances in quantifying the mechanobiology of cardiac development via computational modeling. Curr Opin Biomed Eng. 2023 Mar; 25. Brown AL, Gerosa FM, Wang J, Hsiai T, Marsden AL. PMID: 36583220; PMCID: PMC9794182.
      View in: PubMed   Mentions: 1  
    36. Distinct patterns of responses in endothelial cells and smooth muscle cells following vascular injury. JCI Insight. 2022 10 24; 7(20). Ding X, An Q, Zhao W, Song Y, Tang X, Wang J, Chang CC, Zhao G, Hsiai T, Fan G, Fan Y, Li S. PMID: 36278486; PMCID: PMC9714785.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimalsCells
    37. A wearable electrochemical biosensor for the monitoring of metabolites and nutrients. Nat Biomed Eng. 2022 11; 6(11):1225-1235. Wang M, Yang Y, Min J, Song Y, Tu J, Mukasa D, Ye C, Xu C, Heflin N, McCune JS, Hsiai TK, Li Z, Gao W. PMID: 35970928; PMCID: PMC10432133.
      View in: PubMed   Mentions: 123     Fields:    Translation:Humans
    38. Room-Temperature Annealing-Free Gold Printing via Anion-Assisted Photochemical Deposition. Adv Mater. 2022 Aug; 34(32):e2201772. Wu D, Yao B, Wu S, Hingorani H, Cui Q, Hua M, Frenkel I, Du Y, Hsiai TK, He X. PMID: 35703311; PMCID: PMC9884391.
      View in: PubMed   Mentions: 5     Fields:    
    39. Engineering viral genomics and nano-liposomes in microfluidic platforms for patient-specific analysis of SARS-CoV-2 variants. Theranostics. 2022; 12(10):4779-4790. Satta S, Shahabipour F, Gao W, Lentz SR, Perlman S, Ashammakhi N, Hsiai T. PMID: 35832078; PMCID: PMC9254234.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansAnimalsCellsPHPublic Health
    40. Vascular Injury in the Zebrafish Tail Modulates Blood Flow and Peak Wall Shear Stress to Restore Embryonic Circular Network. Front Cardiovasc Med. 2022; 9:841101. Baek KI, Chang SS, Chang CC, Roustaei M, Ding Y, Wang Y, Chen J, O'Donnell R, Chen H, Ashby JW, Xu X, Mack JJ, Cavallero S, Roper M, Hsiai TK. PMID: 35369301; PMCID: PMC8971683.
      View in: PubMed   Mentions: 4  
    41. An engineered nano-liposome-human ACE2 decoy neutralizes SARS-CoV-2 Spike protein-induced inflammation in both murine and human macrophages. Theranostics. 2022; 12(6):2639-2657. Satta S, Meng Z, Hernandez R, Cavallero S, Zhou T, Hsiai TK, Zhou C. PMID: 35401811; PMCID: PMC8965482.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansAnimalsCells
    42. Computational simulations of the 4D micro-circulatory network in zebrafish tail amputation and regeneration. J R Soc Interface. 2022 02; 19(187):20210898. Roustaei M, In Baek K, Wang Z, Cavallero S, Satta S, Lai A, O'Donnell R, Vedula V, Ding Y, Marsden AL, Hsiai TK. PMID: 35167770; PMCID: PMC8848759.
      View in: PubMed   Mentions: 6     Fields:    Translation:AnimalsCells
    43. An Ex Vivo Study of Outward Electrical Impedance Tomography (OEIT) for Intravascular Imaging. IEEE Trans Biomed Eng. 2022 02; 69(2):734-745. Luo Y, Huang D, Huang ZY, Hsiai TK, Tai YC. PMID: 34383642; PMCID: PMC8837386.
      View in: PubMed   Mentions:    Fields:    Translation:Animals
    44. Development of targeted nanoparticles loaded with antiviral drugs for SARS-CoV-2 inhibition. Eur J Med Chem. 2022 Mar 05; 231:114121. Sanna V, Satta S, Hsiai T, Sechi M. PMID: 35114539; PMCID: PMC8755562.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansCells
    45. 3-Dimensional electrical impedance spectroscopy for in situ endoluminal mapping of metabolically active plaques. Sens Actuators B Chem. 2022 Mar 01; 354. Abiri P, Luo Y, Huang ZY, Cui Q, Duarte-Vogel S, Roustaei M, Chang CC, Xiao X, Packard R, Cavallero S, Ebrahimi R, Benharash P, Chen J, Tai YC, Hsiai TK. PMID: 39391284; PMCID: PMC11466225.
      View in: PubMed   Mentions: 2  
    46. Rapid Detection and Inhibition of SARS-CoV-2-Spike Mutation-Mediated Microthrombosis. Adv Sci (Weinh). 2021 12; 8(23):e2103266. Satta S, Lai A, Cavallero S, Williamson C, Chen J, Blázquez-Medela AM, Roustaei M, Dillon BJ, Ashammakhi N, Carlo DD, Li Z, Sun R, Hsiai TK. PMID: 34687279; PMCID: PMC8646611.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCells
    47. Endothelial mechanotransduction in cardiovascular development and regeneration: emerging approaches and animal models. Curr Top Membr. 2021; 87:131-151. Cavallero S, Blázquez-Medela AM, Satta S, Hsiai TK. PMID: 34696883; PMCID: PMC9113082.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    48. Electrical impedance tomography for non-invasive identification of fatty liver infiltrate in overweight individuals. Sci Rep. 2021 10 06; 11(1):19859. Chang CC, Huang ZY, Shih SF, Luo Y, Ko A, Cui Q, Sumner J, Cavallero S, Das S, Gao W, Sinsheimer J, Bui A, Jacobs JP, Pajukanta P, Wu H, Tai YC, Li Z, Hsiai TK. PMID: 34615918; PMCID: PMC8494919.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    49. Ambulatory Cardiovascular Monitoring Via a Machine-Learning-Assisted Textile Triboelectric Sensor. Adv Mater. 2021 Oct; 33(41):e2104178. Fang Y, Zou Y, Xu J, Chen G, Zhou Y, Deng W, Zhao X, Roustaei M, Hsiai TK, Chen J. PMID: 34467585; PMCID: PMC9205313.
      View in: PubMed   Mentions: 52     Fields:    Translation:Humans
    50. Miniaturized wireless gastric pacing via inductive power transfer with non-invasive monitoring using cutaneous Electrogastrography. Bioelectron Med. 2021 Aug 24; 7(1):12. Perley A, Roustaei M, Aguilar-Rivera M, Kunkel DC, Hsiai TK, Coleman TP, Abiri P. PMID: 34425917; PMCID: PMC8383397.
      View in: PubMed   Mentions: 1  
    51. A hybrid of light-field and light-sheet imaging to study myocardial function and intracardiac blood flow during zebrafish development. PLoS Comput Biol. 2021 07; 17(7):e1009175. Wang Z, Ding Y, Satta S, Roustaei M, Fei P, Hsiai TK. PMID: 34228702; PMCID: PMC8284633.
      View in: PubMed   Mentions: 8     Fields:    Translation:Animals
    52. Key dimensions of post-traumatic stress disorder and endothelial dysfunction: a protocol for a mechanism-focused cohort study. BMJ Open. 2021 05 05; 11(5):e043060. Cleveland S, Reed K, Thomas JL, Ajijola OA, Ebrahimi R, Hsiai T, Lazarov A, Montoya AK, Neria Y, Shimbo D, Wolitzky-Taylor K, Sumner JA. PMID: 33952541; PMCID: PMC8103395.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    53. Association of COVID-19 transmission with high levels of ambient pollutants: Initiation and impact of the inflammatory response on cardiopulmonary disease. Sci Total Environ. 2021 Jul 20; 779:146464. Lai A, Chang ML, O'Donnell RP, Zhou C, Sumner JA, Hsiai TK. PMID: 33961545; PMCID: PMC7960028.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansCellsPHPublic Health
    54. Real-time volumetric reconstruction of biological dynamics with light-field microscopy and deep learning. Nat Methods. 2021 05; 18(5):551-556. Wang Z, Zhu L, Zhang H, Li G, Yi C, Li Y, Yang Y, Ding Y, Zhen M, Gao S, Hsiai TK, Fei P. PMID: 33574612; PMCID: PMC8107123.
      View in: PubMed   Mentions: 59     Fields:    Translation:AnimalsCells
    55. In Vivo Intravascular Pacing Using a Wireless Microscale Stimulator. Ann Biomed Eng. 2021 Sep; 49(9):2094-2102. Abiri P, Duarte-Vogel S, Chou TC, Abiri A, Gudapati V, Yousefi A, Roustaei M, Chang CC, Cui Q, Hsu JJ, Bersohn M, Markovic D, Chen J, Tai YC, Hsiai TK. PMID: 33537925.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimals
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    118. Introduction to the special issue on tissue engineering and regenerative medicine. Ann Biomed Eng. 2014 Jul; 42(7):1355-6. Hsiai T, Li S, Bursac N. PMID: 24923380; PMCID: PMC4089964.
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    119. The atypical Rho GTPase, RhoU, regulates cell-adhesion molecules during cardiac morphogenesis. Dev Biol. 2014 May 15; 389(2):182-91. Dickover M, Hegarty JM, Ly K, Lopez D, Yang H, Zhang R, Tedeschi N, Hsiai TK, Chi NC. PMID: 24607366; PMCID: PMC4101123.
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    120. Stretchable electrochemical impedance sensors for intravascular detection of lipid-rich lesions in New Zealand White rabbits. Biosens Bioelectron. 2014 Apr 15; 54:610-6. Cao H, Yu F, Zhao Y, Scianmarello N, Lee J, Dai W, Jen N, Beebe T, Li R, Ebrahimi R, Chang DS, Mody FV, Pacella J, Tai YC, Hsiai T. PMID: 24333932; PMCID: PMC4048807.
      View in: PubMed   Mentions: 11     Fields:    Translation:Animals
    121. Moving domain computational fluid dynamics to interface with an embryonic model of cardiac morphogenesis. PLoS One. 2013; 8(8):e72924. Lee J, Moghadam ME, Kung E, Cao H, Beebe T, Miller Y, Roman BL, Lien CL, Chi NC, Marsden AL, Hsiai TK. PMID: 24009714; PMCID: PMC3751826.
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    122. Ambient ultrafine particles reduce endothelial nitric oxide production via S-glutathionylation of eNOS. Biochem Biophys Res Commun. 2013 Jul 05; 436(3):462-6. Du Y, Navab M, Shen M, Hill J, Pakbin P, Sioutas C, Hsiai TK, Li R. PMID: 23751346; PMCID: PMC3743434.
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    123. Ambient ultrafine particles alter lipid metabolism and HDL anti-oxidant capacity in LDLR-null mice. J Lipid Res. 2013 Jun; 54(6):1608-1615. Li R, Navab M, Pakbin P, Ning Z, Navab K, Hough G, Morgan TE, Finch CE, Araujo JA, Fogelman AM, Sioutas C, Hsiai T. PMID: 23564731; PMCID: PMC3646462.
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    124. Elevated electrochemical impedance in the endoluminal regions with high shear stress: implication for assessing lipid-rich atherosclerotic lesions. Biosens Bioelectron. 2013 May 15; 43:237-44. Yu F, Lee J, Jen N, Li X, Zhang Q, Tang R, Zhou Q, Kim ES, Hsiai TK. PMID: 23318546; PMCID: PMC3594425.
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    125. Atmospheric ultrafine particles promote vascular calcification via the NF-κB signaling pathway. Am J Physiol Cell Physiol. 2013 Feb 15; 304(4):C362-9. Li R, Mittelstein D, Kam W, Pakbin P, Du Y, Tintut Y, Navab M, Sioutas C, Hsiai T. PMID: 23242187; PMCID: PMC3566535.
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    126. Atrial fibrillation pacing decreases intravascular shear stress in a New Zealand white rabbit model: implications in endothelial function. Biomech Model Mechanobiol. 2013 Aug; 12(4):735-45. Jen N, Yu F, Lee J, Wasmund S, Dai X, Chen C, Chawareeyawong P, Yang Y, Li R, Hamdan MH, Hsiai TK. PMID: 22983703; PMCID: PMC3548016.
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    127. Flexible microelectrode arrays to interface epicardial electrical signals with intracardial calcium transients in zebrafish hearts. Biomed Microdevices. 2012 Apr; 14(2):357-66. Yu F, Zhao Y, Gu J, Quigley KL, Chi NC, Tai YC, Hsiai TK. PMID: 22124886; PMCID: PMC3322508.
      View in: PubMed   Mentions: 16     Fields:    Translation:Animals
    128. Angiopoeitin-2 modulates Survivin expression in OxLDL-induced endothelial cell apoptosis. Biochem Biophys Res Commun. 2012 Jan 06; 417(1):619-22. Li R, Mittelstein D, Fang K, Beebe T, Quigley K, Berliner J, Hsiai TK. PMID: 22182412; PMCID: PMC3260082.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
    129. A dynamic model of calcific nodule destabilization in response to monocyte- and oxidized lipid-induced matrix metalloproteinases. Am J Physiol Cell Physiol. 2012 Feb 15; 302(4):C658-65. Li R, Mittelstein D, Lee J, Fang K, Majumdar R, Tintut Y, Demer LL, Hsiai TK. PMID: 22031601; PMCID: PMC3287359.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansAnimalsCells
    130. Assessing mitochondrial redox status by flow cytometric methods: vascular response to fluid shear stress. Curr Protoc Cytom. 2011 Oct; Chapter 9:9.37.1-9.37.14. Li R, Jen N, Yu F, Hsiai TK. PMID: 21965108; PMCID: PMC3205925.
      View in: PubMed   Mentions: 12     Fields:    Translation:AnimalsCells
    131. Electrochemical impedance spectroscopy to characterize inflammatory atherosclerotic plaques. Biosens Bioelectron. 2011 Dec 15; 30(1):165-73. Yu F, Dai X, Beebe T, Hsiai T. PMID: 21959227; PMCID: PMC3210389.
      View in: PubMed   Mentions: 11     Fields:    Translation:Humans
    132. Oscillatory shear stress induces mitochondrial superoxide production: implication of NADPH oxidase and c-Jun NH2-terminal kinase signaling. Antioxid Redox Signal. 2011 Sep 01; 15(5):1379-88. Takabe W, Jen N, Ai L, Hamilton R, Wang S, Holmes K, Dharbandi F, Khalsa B, Bressler S, Barr ML, Li R, Hsiai TK. PMID: 20919940; PMCID: PMC3144427.
      View in: PubMed   Mentions: 41     Fields:    Translation:HumansAnimalsCells
    133. MEMS thermal sensors to detect changes in heat transfer in the pre-atherosclerotic regions of fat-fed New Zealand white rabbits. Ann Biomed Eng. 2011 Jun; 39(6):1736-44. Yu F, Ai L, Dai W, Rozengurt N, Yu H, Hsiai TK. PMID: 21380571; PMCID: PMC3322507.
      View in: PubMed   Mentions: 6     Fields:    Translation:Animals
    134. Evolving cardiac conduction phenotypes in developing zebrafish larvae: implications to drug sensitivity. Zebrafish. 2010 Dec; 7(4):325-31. Yu F, Huang J, Adlerz K, Jadvar H, Hamdan MH, Chi N, Chen JN, Hsiai TK. PMID: 20958244; PMCID: PMC3005146.
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    135. The effects of rate and rhythm control on blood pressure and antihypertensive drug usage in patients with atrial fibrillation and hypertension enrolled in the AFFIRM trial. J Cardiovasc Electrophysiol. 2010 Oct; 21(10):1094-8. Masood SO, Wasmund SL, Akoum NW, Egger MJ, Hsiai T, Hamdan MH. PMID: 20455988.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    136. Electrochemical impedance spectroscopy to assess vascular oxidative stress. Ann Biomed Eng. 2011 Jan; 39(1):287-96. Yu F, Li R, Ai L, Edington C, Yu H, Barr M, Kim ES, Hsiai TK. PMID: 20652746; PMCID: PMC3322546.
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    137. Real-time assessment of flow reversal in an eccentric arterial stenotic model. J Biomech. 2010 Oct 19; 43(14):2678-83. Ai L, Zhang L, Dai W, Hu C, Shung KK, Hsiai TK. PMID: 20655537; PMCID: PMC2963694.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    138. Diesel exhaust particles modulate vascular endothelial cell permeability: implication of ZO-1 expression. Toxicol Lett. 2010 Sep 01; 197(3):163-8. Li R, Ning Z, Cui J, Yu F, Sioutas C, Hsiai T. PMID: 20576493; PMCID: PMC2907430.
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    139. Ultrafine particles from diesel vehicle emissions at different driving cycles induce differential vascular pro-inflammatory responses: implication of chemical components and NF-kappaB signaling. Part Fibre Toxicol. 2010 Mar 22; 7:6. Li R, Ning Z, Majumdar R, Cui J, Takabe W, Jen N, Sioutas C, Hsiai T. PMID: 20307321; PMCID: PMC2859401.
      View in: PubMed   Mentions: 31     Fields:    Translation:HumansCells
    140. Electrocardiogram signals to assess zebrafish heart regeneration: implication of long QT intervals. Ann Biomed Eng. 2010 Jul; 38(7):2346-57. Yu F, Li R, Parks E, Takabe W, Hsiai TK. PMID: 20221900; PMCID: PMC3117900.
      View in: PubMed   Mentions: 25     Fields:    
    141. Oxidized low-density lipoprotein-activated c-Jun NH2-terminal kinase regulates manganese superoxide dismutase ubiquitination: implication for mitochondrial redox status and apoptosis. Arterioscler Thromb Vasc Biol. 2010 Mar; 30(3):436-41. Takabe W, Li R, Ai L, Yu F, Berliner JA, Hsiai TK. PMID: 20139358; PMCID: PMC3324126.
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    142. Pulsatile shear stress increased mitochondrial membrane potential: implication of Mn-SOD. Biochem Biophys Res Commun. 2009 Oct 16; 388(2):406-12. Li R, Beebe T, Cui J, Rouhanizadeh M, Ai L, Wang P, Gundersen M, Takabe W, Hsiai TK. PMID: 19666009; PMCID: PMC2746082.
      View in: PubMed   Mentions: 15     Fields:    
    143. Real-time intravascular shear stress in the rabbit abdominal aorta. IEEE Trans Biomed Eng. 2009 Jun; 56(6):1755-64. Ai L, Yu H, Dai W, Hale SL, Kloner RA, Hsiai TK. PMID: 19527952; PMCID: PMC3320657.
      View in: PubMed   Mentions: 11     Fields:    
    144. Optimization of intravascular shear stress assessment in vivo. J Biomech. 2009 Jul 22; 42(10):1429-1437. Ai L, Yu H, Takabe W, Paraboschi A, Yu F, Kim ES, Li R, Hsiai TK. PMID: 19457490; PMCID: PMC2777988.
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    145. Micro-electrocardiograms to study post-ventricular amputation of zebrafish heart. Ann Biomed Eng. 2009 May; 37(5):890-901. Sun P, Zhang Y, Yu F, Parks E, Lyman A, Wu Q, Ai L, Hu CH, Zhou Q, Shung K, Lien CL, Hsiai TK. PMID: 19280341; PMCID: PMC6991467.
      View in: PubMed   Mentions: 34     Fields:    Translation:Animals
    146. Spatial mapping of real-time quantitative shear stress with vascular oxidative stress. Annu Int Conf IEEE Eng Med Biol Soc. 2009; 2009:6557-9. Ai L, Hsiai TK. PMID: 19964904.
      View in: PubMed   Mentions:    Fields:    Translation:Animals
    147. Ultrafine particles from diesel engines induce vascular oxidative stress via JNK activation. Free Radic Biol Med. 2009 Mar 15; 46(6):775-82. Li R, Ning Z, Cui J, Khalsa B, Ai L, Takabe W, Beebe T, Majumdar R, Sioutas C, Hsiai T. PMID: 19154785; PMCID: PMC3205928.
      View in: PubMed   Mentions: 36     Fields:    Translation:HumansCells
    148. Hemodynamic forces regulate embryonic stem cell commitment to vascular progenitors. Curr Cardiol Rev. 2008 Nov; 4(4):269-74. Hsiai TK, Wu JC. PMID: 20066134; PMCID: PMC2801858.
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    149. LDL protein nitration: implication for LDL protein unfolding. Arch Biochem Biophys. 2008 Nov 01; 479(1):1-14. Hamilton RT, Asatryan L, Nilsen JT, Isas JM, Gallaher TK, Sawamura T, Hsiai TK. PMID: 18713619; PMCID: PMC2649963.
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    150. Shear stress influences spatial variations in vascular Mn-SOD expression: implication for LDL nitration. Am J Physiol Cell Physiol. 2008 Jun; 294(6):C1576-85. Ai L, Rouhanizadeh M, Wu JC, Takabe W, Yu H, Alavi M, Li R, Chu Y, Miller J, Heistad DD, Hsiai TK. PMID: 18434620; PMCID: PMC3008554.
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    151. Mechanosignal transduction coupling between endothelial and smooth muscle cells: role of hemodynamic forces. Am J Physiol Cell Physiol. 2008 Mar; 294(3):C659-61. Hsiai TK. PMID: 18344280.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimalsCells
    152. Monitoring oxidative stress in vascular endothelial cells in response to fluid shear stress: from biochemical analyses to micro- and nanotechnologies. Methods Enzymol. 2008; 441:111-50. Rouhanizadeh M, Takabe W, Ai L, Yu H, Hsiai T. PMID: 18554532.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimalsCells
    153. Oxidative stress as a regulator of murine atherosclerosis. Curr Drug Targets. 2007 Dec; 8(12):1222-9. Hsiai T, Berliner JA. PMID: 18220699.
      View in: PubMed   Mentions: 7     Fields:    Translation:AnimalsCells
    154. Positron emission tomography imaging of conditional gene activation in the heart. J Mol Cell Cardiol. 2007 Jul; 43(1):18-26. Chang GY, Cao F, Krishnan M, Huang M, Li Z, Xie X, Sheikh AY, Hoyt G, Robbins RC, Hsiai T, Schneider MD, Wu JC. PMID: 17467733; PMCID: PMC2727602.
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    155. Hemodynamics influences vascular peroxynitrite formation: Implication for low-density lipoprotein apo-B-100 nitration. Free Radic Biol Med. 2007 Feb 15; 42(4):519-29. Hsiai TK, Hwang J, Barr ML, Correa A, Hamilton R, Alavi M, Rouhanizadeh M, Cadenas E, Hazen SL. PMID: 17275684; PMCID: PMC2561143.
      View in: PubMed   Mentions: 34     Fields:    Translation:HumansAnimalsCells
    156. Mechanical response of a calcified plaque model to fluid shear force. Ann Biomed Eng. 2006 Oct; 34(10):1535-41. Lin TC, Tintut Y, Lyman A, Mack W, Demer LL, Hsiai TK. PMID: 17006755.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansCells
    157. 17beta-Estradiol reverses shear-stress-mediated low density lipoprotein modifications. Free Radic Biol Med. 2006 Aug 15; 41(4):568-78. Hwang J, Rouhanizadeh M, Hamilton RT, Lin TC, Eiserich JP, Hodis HN, Hsiai TK. PMID: 16863990; PMCID: PMC3320656.
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    158. Role of annexin II in estrogen-induced macrophage matrix metalloproteinase-9 activity: the modulating effect of statins. Atherosclerosis. 2006 Nov; 189(1):76-82. Hwang J, Hodis HN, Hsiai TK, Asatryan L, Sevanian A. PMID: 16386257.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansCells
    159. Spatial variations in shear stress in a 3-D bifurcation model at low Reynolds numbers. Ann Biomed Eng. 2005 Oct; 33(10):1360-74. Rouhanizadeh M, Lin TC, Arcas D, Hwang J, Hsiai TK. PMID: 16240085.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimals
    160. Oxidized phospholipids mediate occludin expression and phosphorylation in vascular endothelial cells. Am J Physiol Heart Circ Physiol. 2006 Feb; 290(2):H674-83. DeMaio L, Rouhanizadeh M, Reddy S, Sevanian A, Hwang J, Hsiai TK. PMID: 16172163.
      View in: PubMed   Mentions: 22     Fields:    Translation:AnimalsCells
    161. Oxidized-1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphorylcholine induces vascular endothelial superoxide production: implication of NADPH oxidase. Free Radic Biol Med. 2005 Dec 01; 39(11):1512-22. Rouhanizadeh M, Hwang J, Clempus RE, Marcu L, Lassègue B, Sevanian A, Hsiai TK. PMID: 16274886; PMCID: PMC2672101.
      View in: PubMed   Mentions: 25     Fields:    
    162. Micro sensors: linking real-time oscillatory shear stress with vascular inflammatory responses. Ann Biomed Eng. 2004 Feb; 32(2):189-201. Hsiai TK, Cho SK, Wong PK, Ing MH, Salazar A, Hama S, Navab M, Demer LL, Ho CM. PMID: 15008367.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimalsCells
    163. Detection of oxidized low density lipoproteins by indium oxide nanowires-based field effect transistor. Conf Proc IEEE Eng Med Biol Soc. 2004; 2006:204-7. Rouhanizadeh M, Tang T, Li C, DeMaio L, Zhou C, Hsiai T. PMID: 17271645.
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    164. MEMS shear stress sensors for cardiovascular diagnostics. Conf Proc IEEE Eng Med Biol Soc. 2004; 2004:2420-3. Soundararajan G, Hsiai TK, DeMaio L, Chang M, Chang S. PMID: 17270760.
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    165. Pulsatile versus oscillatory shear stress regulates NADPH oxidase subunit expression: implication for native LDL oxidation. Circ Res. 2003 Dec 12; 93(12):1225-32. Hwang J, Ing MH, Salazar A, Lassègue B, Griendling K, Navab M, Sevanian A, Hsiai TK. PMID: 14593003; PMCID: PMC4433384.
      View in: PubMed   Mentions: 128     Fields:    Translation:AnimalsCells
    166. Monocyte recruitment to endothelial cells in response to oscillatory shear stress. FASEB J. 2003 Sep; 17(12):1648-57. Hsiai TK, Cho SK, Wong PK, Ing M, Salazar A, Sevanian A, Navab M, Demer LL, Ho CM. PMID: 12958171; PMCID: PMC4108745.
      View in: PubMed   Mentions: 50     Fields:    Translation:Cells
    167. Endothelial cell dynamics under pulsating flows: significance of high versus low shear stress slew rates (d(tau)/dt). Ann Biomed Eng. 2002 May; 30(5):646-56. Hsiai TK, Cho SK, Honda HM, Hama S, Navab M, Demer LL, Ho CM. PMID: 12108839.
      View in: PubMed   Mentions: 19     Fields:    Translation:AnimalsCells
    168. Pulsatile flow regulates monocyte adhesion to oxidized lipid-induced endothelial cells. Arterioscler Thromb Vasc Biol. 2001 Nov; 21(11):1770-6. Hsiai TK, Cho SK, Reddy S, Hama S, Navab M, Demer LL, Honda HM, Ho CM. PMID: 11701464.
      View in: PubMed   Mentions: 21     Fields:    Translation:AnimalsCells
    169. A complex flow pattern of low shear stress and flow reversal promotes monocyte binding to endothelial cells. Atherosclerosis. 2001 Oct; 158(2):385-90. Honda HM, Hsiai T, Wortham CM, Chen M, Lin H, Navab M, Demer LL. PMID: 11583717.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansAnimalsCells
    170. Prognostic value of coronary calcification and angiographic stenoses in patients undergoing coronary angiography. J Am Coll Cardiol. 1996 Feb; 27(2):285-90. Detrano R, Hsiai T, Wang S, Puentes G, Fallavollita J, Shields P, Stanford W, Wolfkiel C, Georgiou D, Budoff M, Reed J. PMID: 8557895.
      View in: PubMed   Mentions: 56     Fields:    Translation:Humans
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