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Kristina Bostrom

Title(s)Professor, Medicine
SchoolMedicine
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    Collapse Research 
    Collapse research activities and funding
    Role of The Endothelium In Vascular Calcification
    NIH R01HL112839Feb 1, 2013 - Jan 31, 2018
    Role: Principal Investigator
    Molecular Mechanisms of MGP; Role in AVMs
    NIH R01HL081397Jul 1, 2005 - Mar 31, 2022
    Role: Principal Investigator
    MOLECULAR MECHANISMS OF MATRIX GLA PROTEIN
    NIH K08HL004270Apr 1, 2000 - Mar 31, 2005
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Regulating the cell differentiation trajectory of progenitor cells in adipose tissue fibrosis. Mol Metab. 2025 Oct; 100:102231. Zhang L, Cai X, Wu X, Jing Z, Zhao Y, Yao Y, Boström KI. PMID: 40780446; PMCID: PMC12396487.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    2. Two-step regulation by matrix Gla protein in brown adipose cell differentiation. Mol Metab. 2024 Feb; 80:101870. Zhang L, Cai X, Ma F, Qiao X, Ji J, Ma JA, Vergnes L, Zhao Y, Yao Y, Wu X, Boström KI. PMID: 38184275; PMCID: PMC10832489.
      View in: PubMed   Mentions:    Fields:    Translation:Cells
    3. DASH-HF Study: A Pragmatic Quality Improvement Randomized Implementation Trial for Patients With Heart Failure With Reduced Ejection Fraction. Circ Heart Fail. 2023 09; 16(9):e010278. Verma A, Fonarow GC, Hsu JJ, Jackevicius CA, Vaghaiwalla Mody F, Nguyen A, Amidi O, Goldberg S, Vetrivel R, Upparapalli D, Theodoropoulos K, Gregorio S, Chang DS, Bostrom K, Althouse AD, Ziaeian B. PMID: 37494051; PMCID: PMC10524378.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    4. The design of the Dashboard Activated Services and Telehealth for Heart Failure (DASH-HF) study: A pragmatic quality improvement randomized implementation trial for patients with heart failure with reduced ejection fraction. Contemp Clin Trials. 2022 09; 120:106895. Verma A, Fonarow GC, Hsu JJ, Jackevicius CA, Mody FV, Amidi O, Goldberg S, Upparapalli D, Theodoropoulos K, Gregorio S, Chang DS, Bostrom K, Althouse AD, Ziaeian B. PMID: 36028192; PMCID: PMC9635621.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    5. Progenitor cells from brown adipose tissue undergo neurogenic differentiation. Sci Rep. 2022 04 04; 12(1):5614. Jumabay M, Zhang L, Yao J, Boström KI. PMID: 35379860; PMCID: PMC8980074.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    6. Three-dimensional Imaging Coupled with Topological Quantification Uncovers Retinal Vascular Plexuses Undergoing Obliteration. Theranostics. 2021; 11(3):1162-1175. Chang CC, Chu A, Meyer S, Ding Y, Sun MM, Abiri P, Baek KI, Gudapati V, Ding X, Guihard P, Bostrom KI, Li S, Gordon LK, Zheng JJ, Hsiai TK. PMID: 33391527; PMCID: PMC7738897.
      View in: PubMed   Mentions: 4     Fields:    Translation:Animals
    7. Pronethalol Reduces Sox2 (SRY [Sex-Determining Region Y]-Box 2) to Ameliorate Vascular Calcification. Arterioscler Thromb Vasc Biol. 2021 02; 41(2):931-933. Zhang D, Qiao X, Yao J, Zhang L, Wu X, Ma J, Cai X, Bostrom KI, Yao Y. PMID: 33297753; PMCID: PMC8105260.
      View in: PubMed   Mentions: 6     Fields:    Translation:AnimalsCells
    8. Homeobox D3, A Novel Link Between Bone Morphogenetic Protein 9 and Transforming Growth Factor Beta 1 Signaling. J Mol Biol. 2020 03 27; 432(7):2030-2041. Wang L, Yao J, Yu T, Zhang D, Qiao X, Yao Z, Wu X, Zhang L, Boström KI, Yao Y. PMID: 32061928; PMCID: PMC7225048.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimalsCells
    9. Skip is essential for Notch signaling to induce Sox2 in cerebral arteriovenous malformations. Cell Signal. 2020 04; 68:109537. Zhang D, Qiao X, Wang L, Zhang L, Yao J, Wu X, Yu T, Boström KI, Yao Y. PMID: 31927035; PMCID: PMC7147809.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    10. Generation of Vascular Networks from Adipocytes In Vitro. Int J Cell Sci Mol Biol. 2019; 6(2). Medela AMB, Penton A, Bostrom KI, Saparov A, Jumabay M. PMID: 33954280; PMCID: PMC8095932.
      View in: PubMed   Mentions:
    11. Crosstalk between BMP and Notch Induces Sox2 in Cerebral Endothelial Cells. Cells. 2019 06 06; 8(6). Wu X, Yao J, Wang L, Zhang D, Zhang L, Reynolds EX, Yu T, Boström KI, Yao Y. PMID: 31174355; PMCID: PMC6628192.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansAnimalsCells
    12. Noggin depletion in adipocytes promotes obesity in mice. Mol Metab. 2019 07; 25:50-63. Blázquez-Medela AM, Jumabay M, Rajbhandari P, Sallam T, Guo Y, Yao J, Vergnes L, Reue K, Zhang L, Yao Y, Fogelman AM, Tontonoz P, Lusis AJ, Wu X, Boström KI. PMID: 31027994; PMCID: PMC6600080.
      View in: PubMed   Mentions: 12     Fields:    Translation:AnimalsCells
    13. The Shifting Nature of Endothelial Progenitor Cells in Aortic Stenosis. Mayo Clin Proc. 2019 04; 94(4):567-569. Boström KI. PMID: 30947828.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    14. Association of dairy intake with cardiovascular disease and mortality in 21 countries from five continents (PURE): a prospective cohort study. Lancet. 2018 11 24; 392(10161):2288-2297. Dehghan M, Mente A, Rangarajan S, Sheridan P, Mohan V, Iqbal R, Gupta R, Lear S, Wentzel-Viljoen E, Avezum A, Lopez-Jaramillo P, Mony P, Varma RP, Kumar R, Chifamba J, Alhabib KF, Mohammadifard N, Oguz A, Lanas F, Rozanska D, Bostrom KB, Yusoff K, Tsolkile LP, Dans A, Yusufali A, Orlandini A, Poirier P, Khatib R, Hu B, Wei L, Yin L, Deeraili A, Yeates K, Yusuf R, Ismail N, Mozaffarian D, Teo K, Anand SS, Yusuf S, Prospective Urban Rural Epidemiology (PURE) study investigators. PMID: 30217460.
      View in: PubMed   Mentions: 187     Fields:    Translation:Humans
    15. Vascular endothelium plays a key role in directing pulmonary epithelial cell differentiation. J Cell Biol. 2017 10 02; 216(10):3369-3385. Yao J, Guihard PJ, Wu X, Blazquez-Medela AM, Spencer MJ, Jumabay M, Tontonoz P, Fogelman AM, Boström KI, Yao Y. PMID: 28838957; PMCID: PMC5626536.
      View in: PubMed   Mentions: 23     Fields:    Translation:AnimalsCells
    16. Transgenic tomatoes expressing the 6F peptide and ezetimibe prevent diet-induced increases of IFN-β and cholesterol 25-hydroxylase in jejunum. J Lipid Res. 2017 08; 58(8):1636-1647. Mukherjee P, Hough G, Chattopadhyay A, Navab M, Fogelman HR, Meriwether D, Williams K, Bensinger S, Moller T, Faull KF, Lusis AJ, Iruela-Arispe ML, Bostrom KI, Tontonoz P, Reddy ST, Fogelman AM. PMID: 28592401; PMCID: PMC5538285.
      View in: PubMed   Mentions: 11     Fields:    Translation:Animals
    17. Endothelial-mesenchymal transition in atherosclerotic lesion calcification. Atherosclerosis. 2016 10; 253:124-127. Boström KI, Yao J, Guihard PJ, Blazquez-Medela AM, Yao Y. PMID: 27615595; PMCID: PMC5064862.
      View in: PubMed   Mentions: 46     Fields:    Translation:HumansAnimalsCells
    18. Where do we stand on vascular calcification? Vascul Pharmacol. 2016 09; 84:8-14. Boström KI. PMID: 27260939; PMCID: PMC5097669.
      View in: PubMed   Mentions: 31     Fields:    Translation:HumansAnimalsCells
    19. Response to Pomozi et al's research commentary. Circ Res. 2013 May 24; 112(11):e152-3. Martin LJ, Lau E, Singh H, Vergnes L, Tarling EJ, Mehrabian M, Mungrue I, Xiao S, Shih D, Castellani L, Ping P, Reue K, Stefani E, Drake TA, Bostrom K, Lusis AJ. PMID: 23625949; PMCID: PMC3999040.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimalsCells
    20. ABCC6 localizes to the mitochondria-associated membrane. Circ Res. 2012 Aug 17; 111(5):516-20. Martin LJ, Lau E, Singh H, Vergnes L, Tarling EJ, Mehrabian M, Mungrue I, Xiao S, Shih D, Castellani L, Ping P, Reue K, Stefani E, Drake TA, Bostrom K, Lusis AJ. PMID: 22811557; PMCID: PMC3540978.
      View in: PubMed   Mentions: 30     Fields:    Translation:AnimalsCells
    21. Concise review: applying stem cell biology to vascular structures. Stem Cells. 2012 Mar; 30(3):386-91. Boström KI, Garfinkel A, Yao Y, Jumabay M. PMID: 22232064; PMCID: PMC3592494.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimalsCells
    22. The regulation of valvular and vascular sclerosis by osteogenic morphogens. Circ Res. 2011 Aug 19; 109(5):564-77. Boström KI, Rajamannan NM, Towler DA. PMID: 21852555; PMCID: PMC3167074.
      View in: PubMed   Mentions: 99     Fields:    Translation:HumansAnimalsCells
    23. Matrix GLA protein stimulates VEGF expression through increased transforming growth factor-beta1 activity in endothelial cells. J Biol Chem. 2004 Dec 17; 279(51):52904-13. Boström K, Zebboudj AF, Yao Y, Lin TS, Torres A. PMID: 15456771.
      View in: PubMed   Mentions: 58     Fields:    Translation:HumansAnimalsCells
    24. Insights into the mechanism of vascular calcification. Am J Cardiol. 2001 Jul 19; 88(2A):20E-22E. Boström K. PMID: 11473740.
      View in: PubMed   Mentions: 21     Fields:    Translation:HumansAnimals
    25. Placental calcification: a metastatic process? Placenta. 2001 Jul; 22(6):591-6. Poggi SH, Bostrom KI, Demer LL, Skinner HC, Koos BJ. PMID: 11440548.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansAnimals
    26. Matrix GLA protein modulates differentiation induced by bone morphogenetic protein-2 in C3H10T1/2 cells. J Biol Chem. 2001 Apr 27; 276(17):14044-52. Boström K, Tsao D, Shen S, Wang Y, Demer LL. PMID: 11278388.
      View in: PubMed   Mentions: 68     Fields:    Translation:HumansAnimalsCells
    27. HOXB7 overexpression promotes differentiation of C3H10T1/2 cells to smooth muscle cells. J Cell Biochem. 2000 May; 78(2):210-21. Boström K, Tintut Y, Kao SC, Stanford WP, Demer LL. PMID: 10842316.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansAnimalsCells
    28. Cell differentiation in vascular calcification. Z Kardiol. 2000; 89 Suppl 2:69-74. Boström KI. PMID: 10769406.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansAnimals
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