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Intestinal IFNα4 promotes 15-HETE diet-induced pulmonary hypertension. Respir Res. 2024 Nov 28; 25(1):419.
Ruffenach G, Medzikovic L, Aryan L, Sun W, Lertpanit L, O'Connor E, Dehghanitafti A, Hatamnejad MR, Li M, Reddy ST, Eghbali M. PMID: 39609844; PMCID: PMC11606228.
View in:
PubMed Mentions:
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Disease response in rheumatoid arthritis across four biologic therapies associates with improvement in paraoxonase-1 activity and oxylipins. RMD Open. 2024 Oct 26; 10(4).
Razmjou AA, Kremer JM, Pappas DA, Curtis JR, Wang J, Shahbazian A, Elashoff DA, Guo R, Meriwether D, Sulaiman D, O'Connor E, Reddy ST, Charles-Schoeman C. PMID: 39461874; PMCID: PMC11529732.
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PubMed Mentions: Translation:
Humans
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Evidence further linking the intestine to cardiovascular disease. Curr Opin Lipidol. 2024 Oct 01; 35(5):223-227.
Sulaiman D, Reddy ST, Fogelman AM. PMID: 39073599; PMCID: PMC11377042.
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PubMed Mentions: Fields:
Translation:
HumansAnimals
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Ambient Particulate Matter Induces In Vitro Toxicity to Intestinal Epithelial Cells without Exacerbating Acute Colitis Induced by Dextran Sodium Sulfate or 2,4,6-Trinitrobenzenesulfonic Acid. Int J Mol Sci. 2024 Jun 29; 25(13).
Chang C, Louie A, Zhou Y, Gupta R, Liang F, Xanthou G, Ereso J, Koletic C, Yang JC, Sedighian F, Lagishetty V, Arias-Jayo N, Altuwayjiri A, Tohidi R, Navab M, Reddy ST, Sioutas C, Hsiai T, Araujo JA, Jacobs JP. PMID: 39000289; PMCID: PMC11241079.
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PubMed Mentions: Fields:
Translation:
HumansAnimalsCells
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Non-Invasive Detection of Early-Stage Fatty Liver Disease via an On-Skin Impedance Sensor and Attention-Based Deep Learning. Adv Sci (Weinh). 2024 Aug; 11(31):e2400596.
Wang K, Margolis S, Cho JM, Wang S, Arianpour B, Jabalera A, Yin J, Hong W, Zhang Y, Zhao P, Zhu E, Reddy S, Hsiai TK. PMID: 38887178; PMCID: PMC11336938.
View in:
PubMed Mentions:
2 Fields:
Translation:
HumansAnimals
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The Lipid Intensive Drug Therapy for Sepsis Phase II Pilot Clinical Trial. Crit Care Med. 2024 Aug 01; 52(8):1183-1193.
Guirgis FW, Black LP, Henson M, Bertrand A, DeVos E, Ferreira J, Gao H, Wu SS, Leeuwenburgh C, Moldawer L, Moore F, Reddy ST. PMID: 38488429.
View in:
PubMed Mentions: Fields:
Translation:
HumansCTClinical Trials
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Lipidomic changes in a novel sepsis outcome-based analysis reveals potent pro-inflammatory and pro-resolving signaling lipids. Clin Transl Sci. 2024 03; 17(3):e13745.
Sulaiman D, Wu D, Black LP, Williams KJ, Graim K, Datta S, Reddy ST, Guirgis FW. PMID: 38488489; PMCID: PMC10941572.
View in:
PubMed Mentions:
2 Fields:
Translation:
Humans
-
Exercise mitigates flow recirculation and activates metabolic transducer SCD1 to catalyze vascular protective metabolites. Sci Adv. 2024 Feb 16; 10(7):eadj7481.
Cavallero S, Roustaei M, Satta S, Cho JM, Phan H, Baek KI, Blázquez-Medela AM, Gonzalez-Ramos S, Vu K, Park SK, Yokota T, Sumner J, Mack JJ, Sigmund CD, Reddy ST, Li R, Hsiai TK. PMID: 38354249; PMCID: PMC10866565.
View in:
PubMed Mentions:
2 Fields:
Translation:
Animals
-
Subchronic inhalation exposure to ultrafine particulate matter alters the intestinal microbiome in various mouse models. Environ Res. 2024 May 01; 248:118242.
Chang C, Gupta R, Sedighian F, Louie A, Gonzalez DM, Le C, Cho JM, Park SK, Castellanos J, Ting TW, Dong TS, Arias-Jayo N, Lagishetty V, Navab M, Reddy S, Sioutas C, Hsiai T, Jacobs JP, Araujo JA. PMID: 38242419.
View in:
PubMed Mentions:
3 Fields:
Translation:
AnimalsPHPublic Health
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TRENDS IN CHOLESTEROL AND LIPOPROTEINS ARE ASSOCIATED WITH ACUTE RESPIRATORY DISTRESS SYNDROME INCIDENCE AND DEATH AMONG SEPSIS PATIENTS. Shock. 2024 Feb 01; 61(2):260-265.
Black LP, Hopson C, Barker G, Munson T, Henson M, Bertrand A, Daly-Crews K, Reddy ST, Guirgis FW. PMID: 38407817; PMCID: PMC10957110.
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PubMed Mentions: Fields:
Translation:
Humans
-
Correction to: Suppressed paraoxonase-1 activity associates with elevated oxylipins and the presence of small airways disease in patients with rheumatoid arthritis. Clin Rheumatol. 2023 Nov; 42(11):3175.
Razmjou AA, Wang JM, Shahbazian A, Reddy S, Charles-Schoeman C. PMID: 37707640; PMCID: PMC10587016.
View in:
PubMed Mentions: Fields:
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Paraoxonase 2 Deficiency Causes Mitochondrial Dysfunction in Retinal Pigment Epithelial Cells and Retinal Degeneration in Mice. Antioxidants (Basel). 2023 Sep 30; 12(10).
Sreekumar PG, Su F, Spee C, Hong E, Komirisetty R, Araujo E, Nusinowitz S, Reddy ST, Kannan R. PMID: 37891899; PMCID: PMC10604559.
View in:
PubMed Mentions:
3
-
Lipid Mediators and Cytokines/Chemokines Display Differential Profiles in Severe versus Mild/Moderate COVID-19 Patients. Int J Mol Sci. 2023 Aug 22; 24(17).
Ravindran R, O'Connor E, Gupta A, Luciw PA, Khan AI, Dorreh N, Chiang K, Ikram A, Reddy S. PMID: 37685858; PMCID: PMC10488250.
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PubMed Mentions:
2 Fields:
Translation:
Humans
-
Integrating 4-D light-sheet fluorescence microscopy and genetic zebrafish system to investigate ambient pollutants-mediated toxicity. Sci Total Environ. 2023 Dec 01; 902:165947.
Gonzalez-Ramos S, Wang J, Cho JM, Zhu E, Park SK, In JG, Reddy ST, Castillo EF, Campen MJ, Hsiai TK. PMID: 37543337; PMCID: PMC10659062.
View in:
PubMed Mentions:
1 Fields:
Translation:
HumansAnimalsPHPublic Health
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The multiple roles of lysophosphatidic acid in vascular disease and atherosclerosis. Curr Opin Lipidol. 2023 10 01; 34(5):196-200.
Chattopadhyay A, Reddy ST, Fogelman AM. PMID: 37497844.
View in:
PubMed Mentions:
1 Fields:
Translation:
HumansCells
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DHCR7 Expression Predicts Poor Outcomes and Mortality From Sepsis. Crit Care Explor. 2023 Jun; 5(6):e0929.
Guirgis FW, Jacob V, Wu D, Henson M, Daly-Crews K, Hopson C, Black LP, DeVos EL, Sulaiman D, Labilloy G, Brusko TM, Shavit JA, Bertrand A, Feldhammer M, Baskovich B, Graim K, Datta S, Reddy ST. PMID: 37332366; PMCID: PMC10270496.
View in:
PubMed Mentions:
3
-
Stability Characterization of the Novel Anti-Cancer HM-10/10 HDL-Mimetic Peptide. Int J Mol Sci. 2023 Jun 13; 24(12).
Dempsey MP, Andersen KE, Wells BM, Taylor MA, Cashman CL, Conrad LB, Kearney CA, Conklin MB, Via ER, Doe EM, Komirisetty R, Dearborn S, Reddy ST, Farias-Eisner R. PMID: 37373203; PMCID: PMC10298982.
View in:
PubMed Mentions: Fields:
Translation:
Humans
-
Exercise Mitigates Flow Recirculation and Activates Mechanosensitive Transcriptome to Uncover Endothelial SCD1-Catalyzed Anti-Inflammatory Metabolites. bioRxiv. 2023 May 03.
Cavallero S, Roustaei M, Satta S, Cho JM, Phan H, Baek KI, Blázquez-Medela AM, Gonzalez-Ramos S, Vu K, Park SK, Yokota T, Sumner JA, Mack JJ, Sigmund CD, Reddy ST, Li R, Hsiai TK. PMID: 37205360; PMCID: PMC10187200.
View in:
PubMed Mentions:
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Editorial: Pathogenesis in progenitor cells: epigenetics and external influences. Front Cell Dev Biol. 2023; 11:1205372.
Koka PS, Reddy ST. PMID: 37181749; PMCID: PMC10167951.
View in:
PubMed Mentions:
1
-
Vutiglabridin Modulates Paraoxonase 1 and Ameliorates Diet-Induced Obesity in Hyperlipidemic Mice. Biomolecules. 2023 04 18; 13(4).
Sulaiman D, Choi LS, Lee HM, Shin J, Kim DH, Lee KW, Eftekhari P, Quartier A, Park HS, Reddy ST. PMID: 37189434; PMCID: PMC10135725.
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PubMed Mentions: Fields:
Translation:
Animals
-
Role of enterocyte Enpp2 and autotaxin in regulating lipopolysaccharide levels, systemic inflammation, and atherosclerosis. J Lipid Res. 2023 05; 64(5):100370.
Chattopadhyay A, Mukherjee P, Sulaiman D, Wang H, Girjalva V, Dorreh N, Jacobs JP, Delk S, Moolenaar WH, Navab M, Reddy ST, Fogelman AM. PMID: 37059333; PMCID: PMC10200992.
View in:
PubMed Mentions: Fields:
Translation:
AnimalsCells
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DHCR7 Expression Predicts Poor Outcomes and Mortality from Sepsis. Res Sq. 2023 Jan 30.
Guirgis FW, Jacob V, Wu D, Henson M, Daly-Crews K, Hopson C, Black LP, DeVos EL, Sulaiman D, Labilloy G, Brusko TM, Shavit JA, Bertrand A, Feldhammer M, Baskovich B, Graim K, Datta S, Reddy ST. PMID: 36778468; PMCID: PMC9915766.
View in:
PubMed Mentions:
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Oxidative Stress and Lipid Accumulation Augments Cell Death in LDLR-Deficient RPE Cells and Ldlr-/- Mice. Cells. 2022 12 22; 12(1).
Sreekumar PG, Su F, Spee C, Araujo E, Nusinowitz S, Reddy ST, Kannan R. PMID: 36611838; PMCID: PMC9818299.
View in:
PubMed Mentions:
7 Fields:
Translation:
HumansAnimals
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Suppressed paraoxonase-1 activity associates with elevated oxylipins and the presence of small airways disease in patients with rheumatoid arthritis. Clin Rheumatol. 2023 Jan; 42(1):75-82.
Razmjou AA, Wang JM, Shahbazian A, Reddy S, Charles-Schoeman C. PMID: 36138190; PMCID: PMC9823017.
View in:
PubMed Mentions:
2 Fields:
Translation:
Humans
-
The role of gut-derived oxidized lipids and bacterial lipopolysaccharide in systemic inflammation and atherosclerosis. Curr Opin Lipidol. 2022 10 01; 33(5):277-282.
Wang H, Reddy ST, Fogelman AM. PMID: 35979993; PMCID: PMC9581106.
View in:
PubMed Mentions:
6 Fields:
Translation:
Humans
-
Abnormal paraoxonase-1 (PON1) enzyme activity in idiopathic inflammatory myopathies. Rheumatology (Oxford). 2022 05 30; 61(6):2512-2523.
Bae SS, Shahbazian A, Wang J, Golub I, Oganesian B, Dowd T, Vayngortin B, Wang R, Elashoff D, Reddy ST, Charles-Schoeman C. PMID: 34698804; PMCID: PMC9308379.
View in:
PubMed Mentions:
1 Fields:
Translation:
Humans
-
Differential Peripheral Blood Glycoprotein Profiles in Symptomatic and Asymptomatic COVID-19. Viruses. 2022 03 07; 14(3).
Pickering C, Zhou B, Xu G, Rice R, Ramachandran P, Huang H, Pham TD, Schapiro JM, Cong X, Chakraborty S, Edwards K, Reddy ST, Guirgis F, Wang TT, Serie D, Lindpaintner K. PMID: 35336960; PMCID: PMC8951729.
View in:
PubMed Mentions:
5 Fields:
Translation:
Humans
-
Ramatroban for chemoprophylaxis and treatment of COVID-19: David takes on Goliath. Expert Opin Ther Targets. 2022 01; 26(1):13-28.
Chiang KC, Rizk JG, Nelson DJ, Krishnamurti L, Subbian S, Imig JD, Khan I, Reddy ST, Gupta A. PMID: 35068281; PMCID: PMC10119876.
View in:
PubMed Mentions:
4 Fields:
Translation:
HumansAnimalsCells
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Macrophage COX2 Mediates Efferocytosis, Resolution Reprogramming, and Intestinal Epithelial Repair. Cell Mol Gastroenterol Hepatol. 2022; 13(4):1095-1120.
Meriwether D, Jones AE, Ashby JW, Solorzano-Vargas RS, Dorreh N, Noori S, Grijalva V, Ball AB, Semis M, Divakaruni AS, Mack JJ, Herschman HR, Martin MG, Fogelman AM, Reddy ST. PMID: 35017061; PMCID: PMC8873959.
View in:
PubMed Mentions:
12 Fields:
Translation:
AnimalsCells
-
ApoA-I mimetics reduce systemic and gut inflammation in chronic treated HIV. PLoS Pathog. 2022 01; 18(1):e1010160.
Daskou M, Mu W, Sharma M, Vasilopoulos H, Heymans R, Ritou E, Rezek V, Hamid P, Kossyvakis A, Sen Roy S, Grijalva V, Chattopadhyay A, Kitchen SG, Fogelman AM, Reddy ST, Kelesidis T. PMID: 34995311; PMCID: PMC8740974.
View in:
PubMed Mentions:
6 Fields:
Translation:
HumansAnimals
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Mechanisms of RPE senescence and potential role of αB crystallin peptide as a senolytic agent in experimental AMD. Exp Eye Res. 2022 02; 215:108918.
Sreekumar PG, Reddy ST, Hinton DR, Kannan R. PMID: 34986369; PMCID: PMC8923947.
View in:
PubMed Mentions:
15 Fields:
Translation:
Animals
-
The ApoA-I mimetic peptide 4F attenuates in vitro replication of SARS-CoV-2, associated apoptosis, oxidative stress and inflammation in epithelial cells. Virulence. 2021 12; 12(1):2214-2227.
Kelesidis T, Madhav S, Petcherski A, Cristelle H, O'Connor E, Hultgren NW, Ritou E, Williams DS, Shirihai OS, Reddy ST. PMID: 34494942; PMCID: PMC8437485.
View in:
PubMed Mentions:
7 Fields:
Translation:
HumansAnimalsCells
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Oxidized phospholipids cause changes in jejunum mucus that induce dysbiosis and systemic inflammation. J Lipid Res. 2022 Jan; 63(1):100153.
Mukherjee P, Chattopadhyay A, Grijalva V, Dorreh N, Lagishetty V, Jacobs JP, Clifford BL, Vallim T, Mack JJ, Navab M, Reddy ST, Fogelman AM. PMID: 34808192; PMCID: PMC8953663.
View in:
PubMed Mentions:
5 Fields:
Translation:
AnimalsCells
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HDL and persistent inflammation immunosuppression and catabolism syndrome. Curr Opin Lipidol. 2021 10 01; 32(5):315-322.
Barker G, Winer JR, Guirgis FW, Reddy S. PMID: 34374677; PMCID: PMC8416792.
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PubMed Mentions:
8 Fields:
Translation:
Humans
-
A hypolipoprotein sepsis phenotype indicates reduced lipoprotein antioxidant capacity, increased endothelial dysfunction and organ failure, and worse clinical outcomes. Crit Care. 2021 09 17; 25(1):341.
Guirgis FW, Black LP, Henson M, Labilloy G, Smotherman C, Hopson C, Tfirn I, DeVos EL, Leeuwenburgh C, Moldawer L, Datta S, Brusko TM, Hester A, Bertrand A, Grijalva V, Arango-Esterhay A, Moore FA, Reddy ST. PMID: 34535154; PMCID: PMC8447561.
View in:
PubMed Mentions:
15 Fields:
Translation:
Humans
-
Iron loading induces cholesterol synthesis and sensitizes endothelial cells to TNFα-mediated apoptosis. J Biol Chem. 2021 10; 297(4):101156.
Fisher AL, Srole DN, Palaskas NJ, Meriwether D, Reddy ST, Ganz T, Nemeth E. PMID: 34480898; PMCID: PMC8463868.
View in:
PubMed Mentions:
8 Fields:
Translation:
HumansCells
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A Single LC-MS/MS Analysis to Quantify CoA Biosynthetic Intermediates and Short-Chain Acyl CoAs. Metabolites. 2021 Jul 21; 11(8).
Jones AE, Arias NJ, Acevedo A, Reddy ST, Divakaruni AS, Meriwether D. PMID: 34436409; PMCID: PMC8401288.
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PubMed Mentions:
5
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Lipid and lipoprotein predictors of functional outcomes and long-term mortality after surgical sepsis. Ann Intensive Care. 2021 May 20; 11(1):82.
Guirgis FW, Leeuwenburgh C, Moldawer L, Ghita G, Black LP, Henson M, DeVos E, Holden D, Efron P, Reddy ST, Moore FA. PMID: 34018068; PMCID: PMC8136376.
View in:
PubMed Mentions:
9
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Lipid and Lipoprotein Dysregulation in Sepsis: Clinical and Mechanistic Insights into Chronic Critical Illness. J Clin Med. 2021 Apr 14; 10(8).
Barker G, Leeuwenburgh C, Brusko T, Moldawer L, Reddy ST, Guirgis FW. PMID: 33920038; PMCID: PMC8071007.
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PubMed Mentions:
29
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Novel Roles of Follistatin/Myostatin in Transforming Growth Factor-β Signaling and Adipose Browning: Potential for Therapeutic Intervention in Obesity Related Metabolic Disorders. Front Endocrinol (Lausanne). 2021; 12:653179.
Pervin S, Reddy ST, Singh R. PMID: 33897620; PMCID: PMC8062757.
View in:
PubMed Mentions:
15 Fields:
Translation:
HumansAnimalsCells
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Apolipoprotein A-I mimetics attenuate macrophage activation in chronic treated HIV. AIDS. 2021 03 15; 35(4):543-553.
Mu W, Sharma M, Heymans R, Ritou E, Rezek V, Hamid P, Kossyvakis A, Sen Roy S, Grijalva V, Chattopadhyay A, Papesh J, Meriwether D, Kitchen SG, Fogelman AM, Reddy ST, Kelesidis T. PMID: 33306550; PMCID: PMC8010648.
View in:
PubMed Mentions:
9 Fields:
Translation:
Animals
-
PON2 subverts metabolic gatekeeper functions in B cells to promote leukemogenesis. Proc Natl Acad Sci U S A. 2021 02 16; 118(7).
Pan L, Hong C, Chan LN, Xiao G, Malvi P, Robinson ME, Geng H, Reddy ST, Lee J, Khairnar V, Cosgun KN, Xu L, Kume K, Sadras T, Wang S, Wajapeyee N, Müschen M. PMID: 33531346; PMCID: PMC7896313.
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PubMed Mentions:
6 Fields:
Translation:
HumansAnimalsCells
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Endometriosis: A Malignant Fingerprint. J Cancer Res Ther Oncol. 2020 Apr; 8(2).
DeAngelo C, Tarasiewicz MB, Strother A, Taggart H, Gray C, Shanahan M, Glowacki C, Khandalavala J, Talaska E, Kinnan A, Coté JJ, Edwards AP, Harper-Harrison G, Casey MJ, Hirai TL, Schultz S, Stines L, Vora R, Boudreau D, Burgart J, Shama M, Watson T, Strasheim L, Thompson R, Lawlor R, Joyce K, Magnuson CM, Driano J, Elger B, Lentino A, Driscoll M, Tidwell E, Sharma A, Walker SR, Jones G, Sharma P, Stessman H, Wu Y, Vadgama J, Chase D, Conrad L, Reddy ST, Farias-Eisner R. PMID: 33644256; PMCID: PMC7909468.
View in:
PubMed Mentions:
3
-
Lipid intensive drug therapy for sepsis pilot: A Bayesian phase I clinical trial. J Am Coll Emerg Physicians Open. 2020 Dec; 1(6):1332-1340.
Guirgis FW, Black LP, DeVos E, Henson M, Ferreira J, Miller T, Rosenthal M, Leeuwenburgh C, Kalynych C, Moldawer L, Jones L, Crandall M, Reddy ST, Gao H, Wu S, Moore F. PMID: 33392541; PMCID: PMC7771745.
View in:
PubMed Mentions:
3
-
Apolipoprotein mimetics in cancer. Semin Cancer Biol. 2021 08; 73:158-168.
Delk SC, Chattopadhyay A, Escola-Gil JC, Fogelman AM, Reddy ST. PMID: 33188891; PMCID: PMC8110614.
View in:
PubMed Mentions:
17 Fields:
Translation:
HumansAnimalsCells
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High- density lipoprotein function is abnormal in idiopathic inflammatory myopathies. Rheumatology (Oxford). 2020 11 01; 59(11):3515-3525.
Bae SS, Lee YY, Shahbazian A, Wang J, Meriwether D, Golub I, Oganesian B, Dowd T, Reddy ST, Charles-Schoeman C. PMID: 32830270; PMCID: PMC7590404.
View in:
PubMed Mentions:
7 Fields:
Translation:
HumansCells
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Suppression of inflammatory arthritis in human serum paraoxonase 1 transgenic mice. Sci Rep. 2020 10 08; 10(1):16848.
Charles-Schoeman C, Wang J, Shahbazian A, Lee YY, Wang X, Grijalva V, Brahn E, Shih DM, Devarajan A, Montano C, Lusis AJ, Reddy ST. PMID: 33033318; PMCID: PMC7546628.
View in:
PubMed Mentions:
9 Fields:
Translation:
HumansAnimalsCells
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Ramatroban as a Novel Immunotherapy for COVID-19. J Mol Genet Med. 2020; 14(3).
Gupta A, Kalantar-Zadeh K, Reddy ST. PMID: 32952595; PMCID: PMC7500620.
View in:
PubMed Mentions:
13
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Oral 15-Hydroxyeicosatetraenoic Acid Induces Pulmonary Hypertension in Mice by Triggering T Cell-Dependent Endothelial Cell Apoptosis. Hypertension. 2020 09; 76(3):985-996.
Ruffenach G, O'Connor E, Vaillancourt M, Hong J, Cao N, Sarji S, Moazeni S, Papesh J, Grijalva V, Cunningham CM, Shu L, Chattopadhyay A, Tiwari S, Mercier O, Perros F, Umar S, Yang X, Gomes AV, Fogelman AM, Reddy ST, Eghbali M. PMID: 32713273; PMCID: PMC8008496.
View in:
PubMed Mentions:
11 Fields:
Translation:
AnimalsCells
-
Quantitative and Qualitative Assessments of Cholesterol Association With Bacterial Infection Type in Sepsis and Septic Shock. J Intensive Care Med. 2021 Jul; 36(7):808-817.
Black LP, Puskarich MA, Henson M, Miller T, Reddy ST, Fernandez R, Guirgis FW. PMID: 32578468; PMCID: PMC8061684.
View in:
PubMed Mentions:
5 Fields:
Translation:
Humans
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Bovine HDL and Dual Domain HDL-Mimetic Peptides Inhibit Tumor Development in Mice. J Cancer Res Ther Oncol. 2020; 8(1).
Su F, Gm A, Palgunachari MN, White CR, Stessman H, Wu Y, Vadgama J, Pietras R, Nguyen D, Reddy ST, Farias-Eisner R. PMID: 32462055; PMCID: PMC7252215.
View in:
PubMed Mentions:
4
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Involvement of Low-Density Lipoprotein Receptor in the Pathogenesis of Pulmonary Hypertension. J Am Heart Assoc. 2020 01 21; 9(2):e012063.
Umar S, Ruffenach G, Moazeni S, Vaillancourt M, Hong J, Cunningham C, Cao N, Navab S, Sarji S, Li M, Lee L, Fishbein G, Ardehali A, Navab M, Reddy ST, Eghbali M. PMID: 31914876; PMCID: PMC7033825.
View in:
PubMed Mentions:
13 Fields:
Translation:
HumansAnimalsCells
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A Novel HDL-Mimetic Peptide HM-10/10 Protects RPE and Photoreceptors in Murine Models of Retinal Degeneration. Int J Mol Sci. 2019 Sep 27; 20(19).
Su F, Spee C, Araujo E, Barron E, Wang M, Ghione C, Hinton DR, Nusinowitz S, Kannan R, Reddy ST, Farias-Eisner R. PMID: 31569695; PMCID: PMC6801888.
View in:
PubMed Mentions:
8 Fields:
Translation:
AnimalsCells
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LIPid Intensive Drug therapy for Sepsis Pilot (LIPIDS-P): Phase I/II clinical trial protocol of lipid emulsion therapy for stabilising cholesterol levels in sepsis and septic shock. BMJ Open. 2019 09 18; 9(9):e029348.
Guirgis FW, Black LP, Rosenthal MD, Henson M, Ferreira J, Leeuwenburgh C, Kalynych C, Moldawer LL, Miller T, Jones L, Crandall M, Reddy ST, Wu SS, Moore FA. PMID: 31537565; PMCID: PMC6756323.
View in:
PubMed Mentions:
9 Fields:
Translation:
HumansCTClinical Trials
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Histological hallmarks and role of Slug/PIP axis in pulmonary hypertension secondary to pulmonary fibrosis. EMBO Mol Med. 2019 09; 11(9):e10061.
Ruffenach G, Umar S, Vaillancourt M, Hong J, Cao N, Sarji S, Moazeni S, Cunningham CM, Ardehali A, Reddy ST, Saggar R, Fishbein G, Eghbali M. PMID: 31468711; PMCID: PMC6728601.
View in:
PubMed Mentions:
11 Fields:
Translation:
HumansAnimalsCells
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HDL and LDL: Potential New Players in Breast Cancer Development. J Clin Med. 2019 Jun 14; 8(6).
Cedó L, Reddy ST, Mato E, Blanco-Vaca F, Escolà-Gil JC. PMID: 31208017; PMCID: PMC6616617.
View in:
PubMed Mentions:
70
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Apolipoprotein A-I mimetics mitigate intestinal inflammation in COX2-dependent inflammatory bowel disease model. J Clin Invest. 2019 06 11; 129(9):3670-3685.
Meriwether D, Sulaiman D, Volpe C, Dorfman A, Grijalva V, Dorreh N, Solorzano-Vargas RS, Wang J, O'Connor E, Papesh J, Larauche M, Trost H, Palgunachari MN, Anantharamaiah GM, Herschman HR, Martin MG, Fogelman AM, Reddy ST. PMID: 31184596; PMCID: PMC6715371.
View in:
PubMed Mentions:
37 Fields:
Translation:
HumansAnimalsCells
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A review of the effects of healthcare disparities on the experience and survival of ovarian cancer patients of different racial and ethnic backgrounds. J Cancer Metastasis Treat. 2019; 5.
Kaufman M, Cruz A, Thompson J, Reddy S, Bansal N, Cohen JG, Wu Y, Vadgama J, Farias-Eisner R. PMID: 31236478; PMCID: PMC6590085.
View in:
PubMed Mentions:
6
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Paraoxonase 2 protects against acute myocardial ischemia-reperfusion injury by modulating mitochondrial function and oxidative stress via the PI3K/Akt/GSK-3β RISK pathway. J Mol Cell Cardiol. 2019 04; 129:154-164.
Sulaiman D, Li J, Devarajan A, Cunningham CM, Li M, Fishbein GA, Fogelman AM, Eghbali M, Reddy ST. PMID: 30802459.
View in:
PubMed Mentions:
31 Fields:
Translation:
HumansAnimalsCells
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PON2 Deficiency Leads to Increased Susceptibility to Diet-Induced Obesity. Antioxidants (Basel). 2019 Jan 11; 8(1).
Shih DM, Meng Y, Sallam T, Vergnes L, Shu ML, Reue K, Tontonoz P, Fogelman AM, Lusis AJ, Reddy ST. PMID: 30641857; PMCID: PMC6356528.
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PubMed Mentions:
14
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HDL inflammatory index correlates with and predicts severity of organ failure in patients with sepsis and septic shock. PLoS One. 2018; 13(9):e0203813.
Guirgis FW, Dodani S, Leeuwenburgh C, Moldawer L, Bowman J, Kalynych C, Grijalva V, Reddy ST, Jones AE, Moore FA. PMID: 30216360; PMCID: PMC6138388.
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PubMed Mentions:
25 Fields:
Translation:
Humans
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Role of enterocyte stearoyl-Co-A desaturase-1 in LDLR-null mice. J Lipid Res. 2018 10; 59(10):1818-1840.
Mukherjee P, Hough G, Chattopadhyay A, Grijalva V, O'Connor EI, Meriwether D, Wagner A, Ntambi JM, Navab M, Reddy ST, Fogelman AM. PMID: 30139760; PMCID: PMC6168294.
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PubMed Mentions:
9 Fields:
Translation:
AnimalsCells
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HDL Cholesterol Efflux is Impaired in Older Patients with Early Sepsis: A Subanalysis of a Prospective Pilot Study. Shock. 2018 07; 50(1):66-70.
Guirgis FW, Leeuwenburgh C, Grijalva V, Bowman J, Kalynych C, Moldawer L, Moore FA, Reddy ST. PMID: 29049133; PMCID: PMC5906212.
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PubMed Mentions:
21 Fields:
Translation:
Humans
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Treating the Intestine with Oral ApoA-I Mimetic Tg6F Reduces Tumor Burden in Mouse Models of Metastatic Lung Cancer. Sci Rep. 2018 06 13; 8(1):9032.
Chattopadhyay A, Yang X, Mukherjee P, Sulaiman D, Fogelman HR, Grijalva V, Dubinett S, Wasler TC, Paul MK, Salehi-Rad R, Mack JJ, Iruela-Arispe ML, Navab M, Fogelman AM, Reddy ST. PMID: 29899427; PMCID: PMC5998131.
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PubMed Mentions:
20 Fields:
Translation:
AnimalsCells
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Paraoxonase 2 prevents the development of heart failure. Free Radic Biol Med. 2018 06; 121:117-126.
Li W, Kennedy D, Shao Z, Wang X, Kamdar AK, Weber M, Mislick K, Kiefer K, Morales R, Agatisa-Boyle B, Shih DM, Reddy ST, Moravec CS, Tang WHW. PMID: 29729330; PMCID: PMC5971153.
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PubMed Mentions:
18 Fields:
Translation:
HumansAnimalsCells
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Metabolic profiling of follistatin overexpression: a novel therapeutic strategy for metabolic diseases. Diabetes Metab Syndr Obes. 2018; 11:65-84.
Singh R, Pervin S, Lee SJ, Kuo A, Grijalva V, David J, Vergnes L, Reddy ST. PMID: 29618935; PMCID: PMC5875402.
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PubMed Mentions:
8
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Paraoxonase 2 overexpression inhibits tumor development in a mouse model of ovarian cancer. Cell Death Dis. 2018 03 12; 9(3):392.
Devarajan A, Su F, Grijalva V, Yalamanchi M, Yalamanchi A, Gao F, Trost H, Nwokedi J, Farias-Eisner G, Farias-Eisner R, Fogelman AM, Reddy ST. PMID: 29531225; PMCID: PMC5847560.
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PubMed Mentions:
19 Fields:
Translation:
HumansAnimalsCells
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Making sense of a seemingly odd connection. Eur Heart J. 2017 12 21; 38(48):3588-3589.
Fogelman AM, Reddy ST. PMID: 29020393; PMCID: PMC6251582.
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PubMed Mentions: Fields:
Translation:
Humans
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High levels of oxidized fatty acids in HDL are associated with impaired HDL function in patients with active rheumatoid arthritis. Clin Rheumatol. 2018 Mar; 37(3):615-622.
Charles-Schoeman C, Meriwether D, Lee YY, Shahbazian A, Reddy ST. PMID: 29129008; PMCID: PMC6148336.
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PubMed Mentions:
21 Fields:
Translation:
HumansCells
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Exploring the Predictive Ability of Dysfunctional High-Density Lipoprotein for Adverse Outcomes in Emergency Department Patients with Sepsis: A Preliminary Investigation. Shock. 2017 11; 48(5):539-544.
Guirgis FW, Dodani S, Moldawer L, Leeuwenburgh C, Bowman J, Kalynych C, Jones AE, Reddy ST, Moore FA. PMID: 28452909; PMCID: PMC5643216.
View in:
PubMed Mentions:
15 Fields:
Translation:
HumansCells
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Transgenic tomatoes expressing the 6F peptide and ezetimibe prevent diet-induced increases of IFN-β and cholesterol 25-hydroxylase in jejunum. J Lipid Res. 2017 08; 58(8):1636-1647.
Mukherjee P, Hough G, Chattopadhyay A, Navab M, Fogelman HR, Meriwether D, Williams K, Bensinger S, Moller T, Faull KF, Lusis AJ, Iruela-Arispe ML, Bostrom KI, Tontonoz P, Reddy ST, Fogelman AM. PMID: 28592401; PMCID: PMC5538285.
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PubMed Mentions:
10 Fields:
Translation:
Animals
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Follistatin Targets Distinct Pathways To Promote Brown Adipocyte Characteristics in Brown and White Adipose Tissues. Endocrinology. 2017 05 01; 158(5):1217-1230.
Singh R, Braga M, Reddy ST, Lee SJ, Parveen M, Grijalva V, Vergnes L, Pervin S. PMID: 28324027; PMCID: PMC5460830.
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PubMed Mentions:
29 Fields:
Translation:
AnimalsCells
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Ambient Ultrafine Particle Ingestion Alters Gut Microbiota in Association with Increased Atherogenic Lipid Metabolites. Sci Rep. 2017 02 17; 7:42906.
Li R, Yang J, Saffari A, Jacobs J, Baek KI, Hough G, Larauche MH, Ma J, Jen N, Moussaoui N, Zhou B, Kang H, Reddy S, Henning SM, Campen MJ, Pisegna J, Li Z, Fogelman AM, Sioutas C, Navab M, Hsiai TK. PMID: 28211537; PMCID: PMC5314329.
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PubMed Mentions:
44 Fields:
Translation:
AnimalsCells
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Improvement of High-Density Lipoprotein Function in Patients With Early Rheumatoid Arthritis Treated With Methotrexate Monotherapy or Combination Therapies in a Randomized Controlled Trial. Arthritis Rheumatol. 2017 01; 69(1):46-57.
Charles-Schoeman C, Yin Lee Y, Shahbazian A, Wang X, Elashoff D, Curtis JR, Navarro-Millán I, Yang S, Chen L, Cofield SS, Moreland LW, Paulus H, O'Dell J, Bathon J, Louis Bridges S, Reddy ST. PMID: 27483410; PMCID: PMC5195879.
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PubMed Mentions:
32 Fields:
Translation:
Humans
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ApoA-I mimetic administration, but not increased apoA-I-containing HDL, inhibits tumour growth in a mouse model of inherited breast cancer. Sci Rep. 2016 11 03; 6:36387.
Cedó L, García-León A, Baila-Rueda L, Santos D, Grijalva V, Martínez-Cignoni MR, Carbó JM, Metso J, López-Vilaró L, Zorzano A, Valledor AF, Cenarro A, Jauhiainen M, Lerma E, Fogelman AM, Reddy ST, Escolà-Gil JC, Blanco-Vaca F. PMID: 27808249; PMCID: PMC5093413.
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PubMed Mentions:
21 Fields:
Translation:
HumansAnimalsCells
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Role of oxidized lipids in pulmonary arterial hypertension. Pulm Circ. 2016 Sep; 6(3):261-73.
Sharma S, Ruffenach G, Umar S, Motayagheni N, Reddy ST, Eghbali M. PMID: 27683603; PMCID: PMC5019079.
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PubMed Mentions:
22
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Transintestinal transport of the anti-inflammatory drug 4F and the modulation of transintestinal cholesterol efflux. J Lipid Res. 2016 07; 57(7):1175-93.
Meriwether D, Sulaiman D, Wagner A, Grijalva V, Kaji I, Williams KJ, Yu L, Fogelman S, Volpe C, Bensinger SJ, Anantharamaiah GM, Shechter I, Fogelman AM, Reddy ST. PMID: 27199144; PMCID: PMC4918848.
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PubMed Mentions:
15 Fields:
Translation:
HumansAnimalsCells
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Apolipoprotein E-/- Mice Lacking Hemopexin Develop Increased Atherosclerosis via Mechanisms That Include Oxidative Stress and Altered Macrophage Function. Arterioscler Thromb Vasc Biol. 2016 06; 36(6):1152-63.
Mehta NU, Grijalva V, Hama S, Wagner A, Navab M, Fogelman AM, Reddy ST. PMID: 27079878; PMCID: PMC4882257.
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PubMed Mentions:
18 Fields:
Translation:
HumansAnimalsCells
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Tg6F ameliorates the increase in oxidized phospholipids in the jejunum of mice fed unsaturated LysoPC or WD. J Lipid Res. 2016 05; 57(5):832-47.
Chattopadhyay A, Navab M, Hough G, Grijalva V, Mukherjee P, Fogelman HR, Hwang LH, Faull KF, Lusis AJ, Reddy ST, Fogelman AM. PMID: 26965826; PMCID: PMC4847630.
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PubMed Mentions:
13 Fields:
Translation:
AnimalsCells
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Proinflammatory high-density lipoprotein results from oxidized lipid mediators in the pathogenesis of both idiopathic and associated types of pulmonary arterial hypertension. Pulm Circ. 2015 Dec; 5(4):640-8.
Ross DJ, Hough G, Hama S, Aboulhosn J, Belperio JA, Saggar R, Van Lenten BJ, Ardehali A, Eghbali M, Reddy S, Fogelman AM, Navab M. PMID: 26697171; PMCID: PMC4671738.
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PubMed Mentions:
29
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Endogenous Sex Steroid Hormones, Lipid Subfractions, and Ectopic Adiposity in Asian Indians. Metab Syndr Relat Disord. 2015 Dec; 13(10):445-52.
Kim C, Kong S, Krauss RM, Stanczyk FZ, Reddy ST, Needham BL, Kanaya AM. PMID: 26431374; PMCID: PMC4696444.
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PubMed Mentions:
3 Fields:
Translation:
Humans
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Role of hemoglobin/heme scavenger protein hemopexin in atherosclerosis and inflammatory diseases. Curr Opin Lipidol. 2015 Oct; 26(5):384-7.
Mehta NU, Reddy ST. PMID: 26339767; PMCID: PMC4826275.
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PubMed Mentions:
17 Fields:
Translation:
HumansAnimalsCells
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Efficacy of tomato concentrates in mouse models of dyslipidemia and cancer. Pharmacol Res Perspect. 2015 Aug; 3(4):e00154.
Chattopadhyay A, Grijalva V, Hough G, Su F, Mukherjee P, Farias-Eisner R, Anantharamaiah GM, Faull KF, Hwang LH, Navab M, Fogelman AM, Reddy ST. PMID: 26171234; PMCID: PMC4492730.
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PubMed Mentions:
13 Fields:
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The dual nature of HDL: Anti-Inflammatory and pro-Inflammatory. Biofactors. 2015 May 06; 41(3):153-9.
Namiri-Kalantari R, Gao F, Chattopadhyay A, Wheeler AA, Navab KD, Farias-Eisner R, Reddy ST. PMID: 26072738.
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PubMed Mentions:
31 Fields:
Translation:
HumansAnimalsCells
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Source and role of intestinally derived lysophosphatidic acid in dyslipidemia and atherosclerosis. J Lipid Res. 2015 Apr; 56(4):871-87.
Navab M, Chattopadhyay A, Hough G, Meriwether D, Fogelman SI, Wagner AC, Grijalva V, Su F, Anantharamaiah GM, Hwang LH, Faull KF, Reddy ST, Fogelman AM. PMID: 25646365; PMCID: PMC4373744.
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PubMed Mentions:
26 Fields:
Translation:
Animals
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PON3 knockout mice are susceptible to obesity, gallstone formation, and atherosclerosis. FASEB J. 2015 Apr; 29(4):1185-97.
Shih DM, Yu JM, Vergnes L, Dali-Youcef N, Champion MD, Devarajan A, Zhang P, Castellani LW, Brindley DN, Jamey C, Auwerx J, Reddy ST, Ford DA, Reue K, Lusis AJ. PMID: 25477283; PMCID: PMC4396607.
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PubMed Mentions:
18 Fields:
Translation:
AnimalsCells
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A high throughput biochemical fluorometric method for measuring lipid peroxidation in HDL. PLoS One. 2014; 9(11):e111716.
Kelesidis T, Roberts CK, Huynh D, Martínez-Maza O, Currier JS, Reddy ST, Yang OO. PMID: 25368900; PMCID: PMC4219769.
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PubMed Mentions:
18 Fields:
Translation:
HumansAnimalsCells
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Carotid intima media thickness and low high-density lipoprotein (HDL) in South Asian immigrants: could dysfunctional HDL be the missing link? Arch Med Sci. 2014 Oct 27; 10(5):870-9.
Dodani S, Dong L, Guirgis FW, Reddy ST. PMID: 25395937; PMCID: PMC4223133.
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PubMed Mentions:
19
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DJ-1 interacts with and regulates paraoxonase-2, an enzyme critical for neuronal survival in response to oxidative stress. PLoS One. 2014; 9(9):e106601.
Parsanejad M, Bourquard N, Qu D, Zhang Y, Huang E, Rousseaux MW, Aleyasin H, Irrcher I, Callaghan S, Vaillant DC, Kim RH, Slack RS, Mak TW, Reddy ST, Figeys D, Park DS. PMID: 25210784; PMCID: PMC4161380.
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PubMed Mentions:
22 Fields:
Translation:
HumansAnimalsCells
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Apolipoprotein A-I mimetics. Curr Opin Lipidol. 2014 Aug; 25(4):304-8.
Reddy ST, Navab M, Anantharamaiah GM, Fogelman AM. PMID: 24977978; PMCID: PMC4213064.
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PubMed Mentions:
22 Fields:
Translation:
HumansAnimals
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Apolipoprotein A-I mimetic peptide 4F rescues pulmonary hypertension by inducing microRNA-193-3p. Circulation. 2014 Aug 26; 130(9):776-85.
Sharma S, Umar S, Potus F, Iorga A, Wong G, Meriwether D, Breuils-Bonnet S, Mai D, Navab K, Ross D, Navab M, Provencher S, Fogelman AM, Bonnet S, Reddy ST, Eghbali M. PMID: 24963038; PMCID: PMC4194270.
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PubMed Mentions:
49 Fields:
Translation:
HumansAnimalsCells
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Follistatin promotes adipocyte differentiation, browning, and energy metabolism. J Lipid Res. 2014 Mar; 55(3):375-84.
Braga M, Reddy ST, Vergnes L, Pervin S, Grijalva V, Stout D, David J, Li X, Tomasian V, Reid CB, Norris KC, Devaskar SU, Reue K, Singh R. PMID: 24443561; PMCID: PMC3934723.
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PubMed Mentions:
52 Fields:
Translation:
AnimalsCells
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Searching for a successful HDL-based treatment strategy. Biochim Biophys Acta. 2014 Jan; 1841(1):162-7.
Reddy ST, Navab M, Anantharamaiah GM, Fogelman AM. PMID: 24466591.
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PubMed Mentions:
16 Fields:
Translation:
HumansAnimals
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Inflammation, infection, cancer and all that…the role of paraoxonases. Adv Exp Med Biol. 2014; 824:33-41.
Devarajan A, Shih D, Reddy ST. PMID: 25038992; PMCID: PMC4405152.
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PubMed Mentions:
29 Fields:
Translation:
HumansAnimalsCells
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Role of inflammation-associated microenvironment in tumorigenesis and metastasis. Curr Cancer Drug Targets. 2014; 14(1):30-45.
Gao F, Liang B, Reddy ST, Farias-Eisner R, Su X. PMID: 24200082.
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PubMed Mentions:
30 Fields:
Translation:
HumansCells
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Protection against ischemia/reperfusion injury by high-density lipoprotein and its components. Circ Res. 2013 Dec 06; 113(12):1281-2.
Fogelman AM, Reddy ST, Navab M. PMID: 24311615.
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PubMed Mentions:
1 Fields:
Translation:
HumansAnimalsCells
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Association of paraoxonase 1 gene polymorphism and enzyme activity with carotid plaque in rheumatoid arthritis. Arthritis Rheum. 2013 Nov; 65(11):2765-72.
Charles-Schoeman C, Lee YY, Shahbazian A, Gorn AH, Fitzgerald J, Ranganath VK, Taylor M, Ragavendra N, McMahon M, Elashoff D, Reddy ST. PMID: 23917967; PMCID: PMC4410876.
View in:
PubMed Mentions:
27 Fields:
Translation:
HumansCells
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Transgenic 6F tomatoes act on the small intestine to prevent systemic inflammation and dyslipidemia caused by Western diet and intestinally derived lysophosphatidic acid. J Lipid Res. 2013 Dec; 54(12):3403-18.
Navab M, Hough G, Buga GM, Su F, Wagner AC, Meriwether D, Chattopadhyay A, Gao F, Grijalva V, Danciger JS, Van Lenten BJ, Org E, Lusis AJ, Pan C, Anantharamaiah GM, Farias-Eisner R, Smyth SS, Reddy ST, Fogelman AM. PMID: 24085744; PMCID: PMC3826687.
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PubMed Mentions:
34 Fields:
Translation:
Animals
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Role of PON2 in innate immune response in an acute infection model. Mol Genet Metab. 2013 Nov; 110(3):362-70.
Devarajan A, Bourquard N, Grijalva VR, Gao F, Ganapathy E, Verma J, Reddy ST. PMID: 23911207; PMCID: PMC3800229.
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PubMed Mentions:
20 Fields:
Translation:
AnimalsCells
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A mechanistic paradigm for broad-spectrum antivirals that target virus-cell fusion. PLoS Pathog. 2013; 9(4):e1003297.
Vigant F, Lee J, Hollmann A, Tanner LB, Akyol Ataman Z, Yun T, Shui G, Aguilar HC, Zhang D, Meriwether D, Roman-Sosa G, Robinson LR, Juelich TL, Buczkowski H, Chou S, Castanho MA, Wolf MC, Smith JK, Banyard A, Kielian M, Reddy S, Wenk MR, Selke M, Santos NC, Freiberg AN, Jung ME, Lee B. PMID: 23637597; PMCID: PMC3630091.
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PubMed Mentions:
61 Fields:
Translation:
AnimalsCells
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A novel approach to oral apoA-I mimetic therapy. J Lipid Res. 2013 Apr; 54(4):995-1010.
Chattopadhyay A, Navab M, Hough G, Gao F, Meriwether D, Grijalva V, Springstead JR, Palgnachari MN, Namiri-Kalantari R, Su F, Van Lenten BJ, Wagner AC, Anantharamaiah GM, Farias-Eisner R, Farias-Eisener R, Reddy ST, Fogelman AM. PMID: 23378594; PMCID: PMC3606004.
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PubMed Mentions:
43 Fields:
Translation:
Animals
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Ir(I)-catalyzed enantioselective decarboxylative allylic etherification: a general method for the asymmetric synthesis of aryl allyl ethers. Org Lett. 2013 Feb 01; 15(3):512-5.
Kim D, Reddy S, Singh OV, Lee JS, Kong SB, Han H. PMID: 23317334.
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PubMed Mentions:
6 Fields:
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Reducing plasma cholesterol is not the end of the quest. Atherosclerosis. 2013 Mar; 227(1):35-6.
Navab M, Shabihkhani M, Navab KD, Vazirian S, Haghnegahdar M, Reddy ST. PMID: 23343594.
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PubMed Mentions: Fields:
Translation:
HumansAnimals
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High-density lipoprotein and 4F peptide reduce systemic inflammation by modulating intestinal oxidized lipid metabolism: novel hypotheses and review of literature. Arterioscler Thromb Vasc Biol. 2012 Nov; 32(11):2553-60.
Navab M, Reddy ST, Van Lenten BJ, Buga GM, Hough G, Wagner AC, Fogelman AM. PMID: 23077141; PMCID: PMC3597084.
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PubMed Mentions:
39 Fields:
Translation:
HumansAnimalsCells
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Macrophage paraoxonase 2 regulates calcium homeostasis and cell survival under endoplasmic reticulum stress conditions and is sufficient to prevent the development of aggravated atherosclerosis in paraoxonase 2 deficiency/apoE-/- mice on a Western diet. Mol Genet Metab. 2012 Nov; 107(3):416-27.
Devarajan A, Grijalva VR, Bourquard N, Meriwether D, Imaizumi S, Shin BC, Devaskar SU, Reddy ST. PMID: 22864055; PMCID: PMC3483415.
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PubMed Mentions:
12 Fields:
Translation:
AnimalsCells
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Effects of lipid-probe interactions in biochemical fluorometric methods that assess HDL redox activity. Lipids Health Dis. 2012 Jul 06; 11:87.
Kelesidis T, Reddy ST, Huynh D, Meriwether D, Fogelman AM, Navab M, Yang OO. PMID: 22768920; PMCID: PMC3409024.
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PubMed Mentions:
13 Fields:
Translation:
HumansCells
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Protectors or Traitors: The Roles of PON2 and PON3 in Atherosclerosis and Cancer. J Lipids. 2012; 2012:342806.
Witte I, Foerstermann U, Devarajan A, Reddy ST, Horke S. PMID: 22666600; PMCID: PMC3361228.
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PubMed Mentions:
43
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Apolipoprotein A-I mimetic peptides inhibit expression and activity of hypoxia-inducible factor-1α in human ovarian cancer cell lines and a mouse ovarian cancer model. J Pharmacol Exp Ther. 2012 Aug; 342(2):255-62.
Gao F, Chattopadhyay A, Navab M, Grijalva V, Su F, Fogelman AM, Reddy ST, Farias-Eisner R. PMID: 22537771; PMCID: PMC3400800.
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PubMed Mentions:
26 Fields:
Translation:
HumansAnimalsCells
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LXRα is uniquely required for maximal reverse cholesterol transport and atheroprotection in ApoE-deficient mice. J Lipid Res. 2012 Jun; 53(6):1126-33.
Hong C, Bradley MN, Rong X, Wang X, Wagner A, Grijalva V, Castellani LW, Salazar J, Realegeno S, Boyadjian R, Fogelman AM, Van Lenten BJ, Reddy ST, Lusis AJ, Tangirala RK, Tontonoz P. PMID: 22454476; PMCID: PMC3351819.
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PubMed Mentions:
20 Fields:
Translation:
AnimalsCells
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HDL mimetics inhibit tumor development in both induced and spontaneous mouse models of colon cancer. Mol Cancer Ther. 2012 Jun; 11(6):1311-9.
Su F, Grijalva V, Navab K, Ganapathy E, Meriwether D, Imaizumi S, Navab M, Fogelman AM, Reddy ST, Farias-Eisner R. PMID: 22416044; PMCID: PMC3374063.
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PubMed Mentions:
44 Fields:
Translation:
AnimalsCells
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Cholesterol efflux by high density lipoproteins is impaired in patients with active rheumatoid arthritis. Ann Rheum Dis. 2012 Jul; 71(7):1157-62.
Charles-Schoeman C, Lee YY, Grijalva V, Amjadi S, FitzGerald J, Ranganath VK, Taylor M, McMahon M, Paulus HE, Reddy ST. PMID: 22267330; PMCID: PMC3428121.
View in:
PubMed Mentions:
85 Fields:
Translation:
HumansAnimalsCells
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Proteomic profiling following immunoaffinity capture of high-density lipoprotein: association of acute-phase proteins and complement factors with proinflammatory high-density lipoprotein in rheumatoid arthritis. Arthritis Rheum. 2012 Jun; 64(6):1828-37.
Watanabe J, Charles-Schoeman C, Miao Y, Elashoff D, Lee YY, Katselis G, Lee TD, Reddy ST. PMID: 22231638; PMCID: PMC3330163.
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PubMed Mentions:
71 Fields:
Translation:
Humans
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D-4F-mediated reduction in metabolites of arachidonic and linoleic acids in the small intestine is associated with decreased inflammation in low-density lipoprotein receptor-null mice. J Lipid Res. 2012 Mar; 53(3):437-445.
Navab M, Reddy ST, Anantharamaiah GM, Hough G, Buga GM, Danciger J, Fogelman AM. PMID: 22167743; PMCID: PMC3276467.
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PubMed Mentions:
40 Fields:
Translation:
Animals
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Protein phosphatase 2A promotes endothelial survival via stabilization of translational inhibitor 4E-BP1 following exposure to tumor necrosis factor-α. Arterioscler Thromb Vasc Biol. 2011 Nov; 31(11):2586-94.
Janzen C, Sen S, Cuevas J, Reddy ST, Chaudhuri G. PMID: 21903942; PMCID: PMC3206633.
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PubMed Mentions:
6 Fields:
Translation:
HumansCells
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Paraoxonase-2 modulates stress response of endothelial cells to oxidized phospholipids and a bacterial quorum-sensing molecule. Arterioscler Thromb Vasc Biol. 2011 Nov; 31(11):2624-33.
Kim JB, Xia YR, Romanoski CE, Lee S, Meng Y, Shi YS, Bourquard N, Gong KW, Port Z, Grijalva V, Reddy ST, Berliner JA, Lusis AJ, Shih DM. PMID: 21836061; PMCID: PMC3244174.
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PubMed Mentions:
21 Fields:
Translation:
HumansCells
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PubMed Mentions:
39 Fields:
Translation:
HumansAnimalsCells
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Paraoxonase-1 and clopidogrel efficacy. Nat Med. 2011 Sep 07; 17(9):1041-2; author reply 1042-4.
Camps J, Joven J, Mackness B, Mackness M, Tawfik D, Draganov D, Costa LG, Paragh G, Seres I, Horke S, James R, Hernández A, Reddy S, Shih D, Navab M, Rochu D, Aviram M. PMID: 21900915.
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PubMed Mentions:
7 Fields:
Translation:
Humans
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Anti-inflammatory and antioxidant properties of HDLs are impaired in type 2 diabetes. Diabetes. 2011 Oct; 60(10):2617-23.
Morgantini C, Natali A, Boldrini B, Imaizumi S, Navab M, Fogelman AM, Ferrannini E, Reddy ST. PMID: 21852676; PMCID: PMC3178289.
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PubMed Mentions:
89 Fields:
Translation:
HumansCells
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Enhancement by LDL of transfer of L-4F and oxidized lipids to HDL in C57BL/6J mice and human plasma. J Lipid Res. 2011 Oct; 52(10):1795-809.
Meriwether D, Imaizumi S, Grijalva V, Hough G, Vakili L, Anantharamaiah GM, Farias-Eisner R, Navab M, Fogelman AM, Reddy ST, Shechter I. PMID: 21804067; PMCID: PMC3173006.
View in:
PubMed Mentions:
13 Fields:
Translation:
HumansAnimalsCells
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Dysfunctional high-density lipoprotein and the potential of apolipoprotein A-1 mimetic peptides to normalize the composition and function of lipoproteins. Circ J. 2011; 75(7):1533-8.
Imaizumi S, Navab M, Morgantini C, Charles-Schoeman C, Su F, Gao F, Kwon M, Ganapathy E, Meriwether D, Farias-Eisner R, Fogelman AM, Reddy ST. PMID: 21628835; PMCID: PMC3625624.
View in:
PubMed Mentions:
19 Fields:
Translation:
HumansAnimals
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D-4F, an apoA-I mimetic peptide, inhibits proliferation and tumorigenicity of epithelial ovarian cancer cells by upregulating the antioxidant enzyme MnSOD. Int J Cancer. 2012 Mar 01; 130(5):1071-81.
Ganapathy E, Su F, Meriwether D, Devarajan A, Grijalva V, Gao F, Chattopadhyay A, Anantharamaiah GM, Navab M, Fogelman AM, Reddy ST, Farias-Eisner R. PMID: 21425255; PMCID: PMC3248802.
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PubMed Mentions:
30 Fields:
Translation:
HumansAnimalsCells
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Impaired hepatic insulin signalling in PON2-deficient mice: a novel role for the PON2/apoE axis on the macrophage inflammatory response. Biochem J. 2011 May 15; 436(1):91-100.
Bourquard N, Ng CJ, Reddy ST. PMID: 21361875; PMCID: PMC3743554.
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PubMed Mentions:
17 Fields:
Translation:
AnimalsCells
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Optimization of microCT imaging and blood vessel diameter quantitation of preclinical specimen vasculature with radiopaque polymer injection medium. PLoS One. 2011 Apr 18; 6(4):e19099.
Vasquez SX, Gao F, Su F, Grijalva V, Pope J, Martin B, Stinstra J, Masner M, Shah N, Weinstein DM, Farias-Eisner R, Reddy ST. PMID: 21533123; PMCID: PMC3078938.
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PubMed Mentions:
35 Fields:
Translation:
Animals
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Intestine may be a major site of action for the apoA-I mimetic peptide 4F whether administered subcutaneously or orally. J Lipid Res. 2011 Jun; 52(6):1200-1210.
Navab M, Reddy ST, Anantharamaiah GM, Imaizumi S, Hough G, Hama S, Fogelman AM. PMID: 21444758; PMCID: PMC3090241.
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PubMed Mentions:
46 Fields:
Translation:
AnimalsCells
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HDL and cardiovascular disease: atherogenic and atheroprotective mechanisms. Nat Rev Cardiol. 2011 Apr; 8(4):222-32.
Navab M, Reddy ST, Van Lenten BJ, Fogelman AM. PMID: 21304474.
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PubMed Mentions:
254 Fields:
Translation:
Humans
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L-5F, an apolipoprotein A-I mimetic, inhibits tumor angiogenesis by suppressing VEGF/basic FGF signaling pathways. Integr Biol (Camb). 2011 Apr; 3(4):479-89.
Gao F, Vasquez SX, Su F, Roberts S, Shah N, Grijalva V, Imaizumi S, Chattopadhyay A, Ganapathy E, Meriwether D, Johnston B, Anantharamaiah GM, Navab M, Fogelman AM, Reddy ST, Farias-Eisner R. PMID: 21283904; PMCID: PMC3248743.
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PubMed Mentions:
46 Fields:
Translation:
HumansAnimalsCells
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Chronic inflammatory disorders and accelerated atherosclerosis: chronic kidney disease. Curr Pharm Des. 2011; 17(1):17-20.
Navab KD, Elboudwarej O, Gharif M, Yu J, Hama SY, Safarpour S, Hough GP, Vakili L, Reddy ST, Navab M, Vaziri ND. PMID: 21222643.
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PubMed Mentions:
28 Fields:
Translation:
HumansAnimalsCells
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Treatment of patients with cardiovascular disease with L-4F, an apo-A1 mimetic, did not improve select biomarkers of HDL function. J Lipid Res. 2011 Feb; 52(2):361-73.
Watson CE, Weissbach N, Kjems L, Ayalasomayajula S, Zhang Y, Chang I, Navab M, Hama S, Hough G, Reddy ST, Soffer D, Rader DJ, Fogelman AM, Schecter A. PMID: 21068008; PMCID: PMC3023557.
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PubMed Mentions:
78 Fields:
Translation:
HumansCells
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Human CYP2S1 metabolizes cyclooxygenase- and lipoxygenase-derived eicosanoids. Drug Metab Dispos. 2011 Feb; 39(2):180-90.
Bui P, Imaizumi S, Beedanagari SR, Reddy ST, Hankinson O. PMID: 21068195; PMCID: PMC3033693.
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PubMed Mentions:
31 Fields:
Translation:
HumansCells
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Apolipoprotein A-I (apoA-I) and apoA-I mimetic peptides inhibit tumor development in a mouse model of ovarian cancer. Proc Natl Acad Sci U S A. 2010 Nov 16; 107(46):19997-20002.
Su F, Kozak KR, Imaizumi S, Gao F, Amneus MW, Grijalva V, Ng C, Wagner A, Hough G, Farias-Eisner G, Anantharamaiah GM, Van Lenten BJ, Navab M, Fogelman AM, Reddy ST, Farias-Eisner R. PMID: 21041624; PMCID: PMC2993420.
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PubMed Mentions:
115 Fields:
Translation:
HumansAnimalsCells
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Apolipoprotein A-I mimetic peptides prevent atherosclerosis development and reduce plaque inflammation in a murine model of diabetes. Diabetes. 2010 Dec; 59(12):3223-8.
Morgantini C, Imaizumi S, Grijalva V, Navab M, Fogelman AM, Reddy ST. PMID: 20826564; PMCID: PMC2992786.
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PubMed Mentions:
39 Fields:
Translation:
AnimalsCells
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Paraoxonase 2 deficiency alters mitochondrial function and exacerbates the development of atherosclerosis. Antioxid Redox Signal. 2011 Feb 01; 14(3):341-51.
Devarajan A, Bourquard N, Hama S, Navab M, Grijalva VR, Morvardi S, Clarke CF, Vergnes L, Reue K, Teiber JF, Reddy ST. PMID: 20578959; PMCID: PMC3011913.
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PubMed Mentions:
99 Fields:
Translation:
HumansAnimalsCells
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Effect of different intravenous iron preparations on lymphocyte intracellular reactive oxygen species generation and subpopulation survival. BMC Nephrol. 2010 Aug 17; 11:16.
Gupta A, Zhuo J, Zha J, Reddy S, Olp J, Pai A. PMID: 20716362; PMCID: PMC2933673.
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PubMed Mentions:
14 Fields:
Translation:
HumansCells
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L-4F differentially alters plasma levels of oxidized fatty acids resulting in more anti-inflammatory HDL in mice. Drug Metab Lett. 2010 Aug; 4(3):139-48.
Imaizumi S, Grijalva V, Navab M, Van Lenten BJ, Wagner AC, Anantharamiah GM, Fogelman AM, Reddy ST. PMID: 20642447; PMCID: PMC3037264.
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PubMed Mentions:
38 Fields:
Translation:
AnimalsCells
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Mitogen-activated protein kinase phosphatase-1 deficiency decreases atherosclerosis in apolipoprotein E null mice by reducing monocyte chemoattractant protein-1 levels. Mol Genet Metab. 2010 Sep; 101(1):66-75.
Imaizumi S, Grijalva V, Priceman S, Wu L, Su F, Farias-Eisner R, Hama S, Navab M, Fogelman AM, Reddy ST. PMID: 20619710; PMCID: PMC3037189.
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PubMed Mentions:
8 Fields:
Translation:
AnimalsCells
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Novel anti-inflammatory functions for endothelial and myeloid cyclooxygenase-2 in a new mouse model of Crohn's disease. Am J Physiol Gastrointest Liver Physiol. 2010 Jun; 298(6):G842-50.
Watanabe J, Lin JA, Narasimha AJ, Shahbazian A, Ishikawa TO, Martin MG, Herschman HR, Reddy ST. PMID: 20299600; PMCID: PMC8875131.
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PubMed Mentions:
4 Fields:
Translation:
AnimalsCells
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Putative innate immunity of antiatherogenic paraoxanase-2 via STAT5 signal transduction in HIV-1 infection of hematopoietic TF-1 cells and in SCID-hu mice. J Stem Cells. 2010; 5(1):43-8.
Yuan J, Devarajan A, Moya-Castro R, Zhang M, Evans S, Bourquard N, Dias P, Lacout C, Vainchenker W, Reddy ST, Koka PS. PMID: 20861927.
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PubMed Mentions:
7 Fields:
Translation:
HumansAnimalsCells
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L-4F alters hyperlipidemic (but not healthy) mouse plasma to reduce platelet aggregation. Arterioscler Thromb Vasc Biol. 2010 Feb; 30(2):283-9.
Buga GM, Navab M, Imaizumi S, Reddy ST, Yekta B, Hough G, Chanslor S, Anantharamaiah GM, Fogelman AM. PMID: 19965777; PMCID: PMC2818809.
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PubMed Mentions:
17 Fields:
Translation:
AnimalsCells
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HDL as a biomarker, potential therapeutic target, and therapy. Diabetes. 2009 Dec; 58(12):2711-7.
Navab M, Anantharamaiah GM, Reddy ST, Van Lenten BJ, Fogelman AM. PMID: 19940234; PMCID: PMC2780869.
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PubMed Mentions:
47 Fields:
Translation:
HumansAnimalsCells
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Absence of myeloid COX-2 attenuates acute inflammation but does not influence development of atherosclerosis in apolipoprotein E null mice. Arterioscler Thromb Vasc Biol. 2010 Feb; 30(2):260-8.
Narasimha AJ, Watanabe J, Ishikawa TO, Priceman SJ, Wu L, Herschman HR, Reddy ST. PMID: 19926832; PMCID: PMC2859183.
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PubMed Mentions:
16 Fields:
Translation:
AnimalsCells
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Abnormal function of high-density lipoprotein is associated with poor disease control and an altered protein cargo in rheumatoid arthritis. Arthritis Rheum. 2009 Oct; 60(10):2870-9.
Charles-Schoeman C, Watanabe J, Lee YY, Furst DE, Amjadi S, Elashoff D, Park G, McMahon M, Paulus HE, Fogelman AM, Reddy ST. PMID: 19790070; PMCID: PMC2828490.
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PubMed Mentions:
73 Fields:
Translation:
Humans
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Validation of serum biomarkers for detection of early- and late-stage endometrial cancer. Am J Obstet Gynecol. 2010 Jan; 202(1):73.e1-5.
Farias-Eisner G, Su F, Robbins T, Kotlerman J, Reddy S, Farias-Eisner R. PMID: 19766980.
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PubMed Mentions:
18 Fields:
Translation:
Humans
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Structure and function of HDL mimetics. Arterioscler Thromb Vasc Biol. 2010 Feb; 30(2):164-8.
Navab M, Shechter I, Anantharamaiah GM, Reddy ST, Van Lenten BJ, Fogelman AM. PMID: 19608977; PMCID: PMC2860541.
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PubMed Mentions:
54 Fields:
Translation:
HumansAnimalsCells
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Hemoglobin and its scavenger protein haptoglobin associate with apoA-1-containing particles and influence the inflammatory properties and function of high density lipoprotein. J Biol Chem. 2009 Jul 03; 284(27):18292-301.
Watanabe J, Grijalva V, Hama S, Barbour K, Berger FG, Navab M, Fogelman AM, Reddy ST. PMID: 19433579; PMCID: PMC2709397.
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PubMed Mentions:
58 Fields:
Translation:
HumansAnimals
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Validation of serum biomarkers for detection of early-stage ovarian cancer. Am J Obstet Gynecol. 2009 Jun; 200(6):639.e1-5.
Nosov V, Su F, Amneus M, Birrer M, Robins T, Kotlerman J, Reddy S, Farias-Eisner R. PMID: 19285648.
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PubMed Mentions:
41 Fields:
Translation:
Humans
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Apolipoprotein A-I mimetic peptides. Curr Atheroscler Rep. 2009 Jan; 11(1):52-7.
Van Lenten BJ, Wagner AC, Anantharamaiah GM, Navab M, Reddy ST, Buga GM, Fogelman AM. PMID: 19080728; PMCID: PMC2856617.
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PubMed Mentions:
38 Fields:
Translation:
HumansAnimals
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Paraoxonase 2 attenuates macrophage triglyceride accumulation via inhibition of diacylglycerol acyltransferase 1. J Lipid Res. 2009 May; 50(5):870-9.
Rosenblat M, Coleman R, Reddy ST, Aviram M. PMID: 19091699; PMCID: PMC2666173.
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PubMed Mentions:
20 Fields:
Translation:
HumansAnimalsCells
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Multiple indications for anti-inflammatory apolipoprotein mimetic peptides. Curr Opin Investig Drugs. 2008 Nov; 9(11):1157-62.
Van Lenten BJ, Navab M, Anantharamaiah GM, Buga GM, Reddy ST, Fogelman AM. PMID: 18951294; PMCID: PMC2856620.
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PubMed Mentions:
20 Fields:
Translation:
HumansAnimals
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The role of dysfunctional HDL in atherosclerosis. J Lipid Res. 2009 Apr; 50 Suppl:S145-9.
Navab M, Reddy ST, Van Lenten BJ, Anantharamaiah GM, Fogelman AM. PMID: 18955731; PMCID: PMC2674720.
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PubMed Mentions:
85 Fields:
Translation:
HumansAnimalsCells
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Host-derived oxidized phospholipids and HDL regulate innate immunity in human leprosy. J Clin Invest. 2008 Aug; 118(8):2917-28.
Cruz D, Watson AD, Miller CS, Montoya D, Ochoa MT, Sieling PA, Gutierrez MA, Navab M, Reddy ST, Witztum JL, Fogelman AM, Rea TH, Eisenberg D, Berliner J, Modlin RL. PMID: 18636118; PMCID: PMC2467381.
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PubMed Mentions:
82 Fields:
Translation:
HumansCells
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Is it just paraoxonase 1 or are other members of the paraoxonase gene family implicated in atherosclerosis? Curr Opin Lipidol. 2008 Aug; 19(4):405-8.
Reddy ST, Devarajan A, Bourquard N, Shih D, Fogelman AM. PMID: 18607188.
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PubMed Mentions:
26 Fields:
Translation:
HumansAnimals
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The early detection of ovarian cancer: from traditional methods to proteomics. Can we really do better than serum CA-125? Am J Obstet Gynecol. 2008 Sep; 199(3):215-23.
Nossov V, Amneus M, Su F, Lang J, Janco JM, Reddy ST, Farias-Eisner R. PMID: 18468571.
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PubMed Mentions:
112 Fields:
Translation:
Humans
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Apo A-1 mimetic peptides as atheroprotective agents in murine models. Curr Drug Targets. 2008 Mar; 9(3):204-9.
Navab M, Anantharamaiah GM, Reddy ST, Van Lenten BJ, Fogelman AM. PMID: 18336238.
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PubMed Mentions:
10 Fields:
Translation:
HumansAnimalsCells
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Validation of candidate serum ovarian cancer biomarkers for early detection. Biomark Insights. 2007 Oct 16; 2:369-75.
Su F, Lang J, Kumar A, Ng C, Hsieh B, Suchard MA, Reddy ST, Farias-Eisner R. PMID: 19662218; PMCID: PMC2717832.
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PubMed Mentions:
24
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D-4F reduces EO6 immunoreactivity, SREBP-1c mRNA levels, and renal inflammation in LDL receptor-null mice fed a Western diet. J Lipid Res. 2008 Jan; 49(1):192-205.
Buga GM, Frank JS, Mottino GA, Hakhamian A, Narasimha A, Watson AD, Yekta B, Navab M, Reddy ST, Anantharamaiah GM, Fogelman AM. PMID: 17925450.
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PubMed Mentions:
31 Fields:
Translation:
AnimalsCells
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High-density lipoprotein: antioxidant and anti-inflammatory properties. Curr Atheroscler Rep. 2007 Sep; 9(3):244-8.
Navab M, Yu R, Gharavi N, Huang W, Ezra N, Lotfizadeh A, Anantharamaiah GM, Alipour N, Van Lenten BJ, Reddy ST, Marelli D. PMID: 18241620.
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PubMed Mentions:
25 Fields:
Translation:
HumansAnimalsCells
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Lipoprotein inflammatory properties and serum amyloid A levels but not cholesterol levels predict lesion area in cholesterol-fed rabbits. J Lipid Res. 2007 Nov; 48(11):2344-53.
Van Lenten BJ, Wagner AC, Navab M, Anantharamaiah GM, Hama S, Reddy ST, Fogelman AM. PMID: 17693626.
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PubMed Mentions:
61 Fields:
Translation:
AnimalsCells
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Characterization of the rat urokinase plasminogen activator receptor promoter in PC12 cells. J Neurosci Res. 2007 Jul; 85(9):1952-8.
Su F, Kozak KR, Herschman H, Reddy ST, Farias-Eisner R. PMID: 17455298.
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PubMed Mentions:
5 Fields:
Translation:
AnimalsCells
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Structural requirements for antioxidative and anti-inflammatory properties of apolipoprotein A-I mimetic peptides. J Lipid Res. 2007 Sep; 48(9):1915-23.
Anantharamaiah GM, Mishra VK, Garber DW, Datta G, Handattu SP, Palgunachari MN, Chaddha M, Navab M, Reddy ST, Segrest JP, Fogelman AM. PMID: 17570869.
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PubMed Mentions:
64 Fields:
Translation:
HumansAnimalsCells
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Differential association of hemoglobin with proinflammatory high density lipoproteins in atherogenic/hyperlipidemic mice. A novel biomarker of atherosclerosis. J Biol Chem. 2007 Aug 10; 282(32):23698-707.
Watanabe J, Chou KJ, Liao JC, Miao Y, Meng HH, Ge H, Grijalva V, Hama S, Kozak K, Buga G, Whitelegge JP, Lee TD, Farias-Eisner R, Navab M, Fogelman AM, Reddy ST. PMID: 17556366.
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PubMed Mentions:
38 Fields:
Translation:
HumansAnimals
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Effects of high-dose atorvastatin on antiinflammatory properties of high density lipoprotein in patients with rheumatoid arthritis: a pilot study. J Rheumatol. 2007 Jul; 34(7):1459-64.
Charles-Schoeman C, Khanna D, Furst DE, McMahon M, Reddy ST, Fogelman AM, Paulus HE, Park GS, Gong T, Ansell BJ. PMID: 17552046.
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PubMed Mentions:
44 Fields:
Translation:
Humans
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Peptide Mimetics of Apolipoproteins Improve HDL Function. J Clin Lipidol. 2007 May; 1(2):142-7.
Navab M, Anantharamaiah GM, Reddy ST, Van Lenten BJ, Buga GM, Fogelman AM. PMID: 18449337; PMCID: PMC2130772.
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PubMed Mentions:
7 Fields:
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Atherogenic diet causes lethal ileo-ceco-colitis in cyclooxygenase-2 deficient mice. Prostaglandins Other Lipid Mediat. 2007 Nov; 84(3-4):98-107.
Lin JA, Watanabe J, Rozengurt N, Narasimha A, Martin MG, Wang J, Braun J, Langenbach R, Reddy ST. PMID: 17991612; PMCID: PMC2701900.
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PubMed Mentions:
6 Fields:
Translation:
Animals
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Adenovirus-mediated expression of human paraoxonase 3 protects against the progression of atherosclerosis in apolipoprotein E-deficient mice. Arterioscler Thromb Vasc Biol. 2007 Jun; 27(6):1368-74.
Ng CJ, Bourquard N, Hama SY, Shih D, Grijalva VR, Navab M, Fogelman AM, Reddy ST. PMID: 17446441.
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PubMed Mentions:
26 Fields:
Translation:
HumansAnimalsCells
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Decreased obesity and atherosclerosis in human paraoxonase 3 transgenic mice. Circ Res. 2007 Apr 27; 100(8):1200-7.
Shih DM, Xia YR, Wang XP, Wang SS, Bourquard N, Fogelman AM, Lusis AJ, Reddy ST. PMID: 17379834; PMCID: PMC3740095.
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PubMed Mentions:
35 Fields:
Translation:
HumansAnimals
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A novel anti-atherogenic role for COX-2--potential mechanism for the cardiovascular side effects of COX-2 inhibitors. Prostaglandins Other Lipid Mediat. 2007 Aug; 84(1-2):24-33.
Narasimha A, Watanabe J, Lin JA, Hama S, Langenbach R, Navab M, Fogelman AM, Reddy ST. PMID: 17643885; PMCID: PMC2701232.
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PubMed Mentions:
14 Fields:
Translation:
Animals
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Paraoxonase-2 deficiency enhances Pseudomonas aeruginosa quorum sensing in murine tracheal epithelia. Am J Physiol Lung Cell Mol Physiol. 2007 Apr; 292(4):L852-60.
Stoltz DA, Ozer EA, Ng CJ, Yu JM, Reddy ST, Lusis AJ, Bourquard N, Parsek MR, Zabner J, Shih DM. PMID: 17122353.
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PubMed Mentions:
63 Fields:
Translation:
HumansAnimalsCells
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Apolipoprotein A-I mimetic peptides and their role in atherosclerosis prevention. Nat Clin Pract Cardiovasc Med. 2006 Oct; 3(10):540-7.
Navab M, Anantharamaiah GM, Reddy ST, Fogelman AM. PMID: 16990839.
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PubMed Mentions:
56 Fields:
Translation:
HumansAnimalsCells
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Mechanisms of disease: proatherogenic HDL--an evolving field. Nat Clin Pract Endocrinol Metab. 2006 Sep; 2(9):504-11.
Navab M, Anantharamaiah GM, Reddy ST, Van Lenten BJ, Ansell BJ, Fogelman AM. PMID: 16957764.
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PubMed Mentions:
86 Fields:
Translation:
HumansAnimals
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Adenovirus mediated expression of human paraoxonase 2 protects against the development of atherosclerosis in apolipoprotein E-deficient mice. Mol Genet Metab. 2006 Dec; 89(4):368-73.
Ng CJ, Hama SY, Bourquard N, Navab M, Reddy ST. PMID: 16935014.
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PubMed Mentions:
32 Fields:
Translation:
AnimalsCells
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Paraoxonase-2 deficiency aggravates atherosclerosis in mice despite lower apolipoprotein-B-containing lipoproteins: anti-atherogenic role for paraoxonase-2. J Biol Chem. 2006 Oct 06; 281(40):29491-500.
Ng CJ, Bourquard N, Grijalva V, Hama S, Shih DM, Navab M, Fogelman AM, Lusis AJ, Young S, Reddy ST. PMID: 16891303.
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PubMed Mentions:
71 Fields:
Translation:
AnimalsCells
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Effect of altering dietary omega-6/omega-3 fatty acid ratios on prostate cancer membrane composition, cyclooxygenase-2, and prostaglandin E2. Clin Cancer Res. 2006 Aug 01; 12(15):4662-70.
Kobayashi N, Barnard RJ, Henning SM, Elashoff D, Reddy ST, Cohen P, Leung P, Hong-Gonzalez J, Freedland SJ, Said J, Gui D, Seeram NP, Popoviciu LM, Bagga D, Heber D, Glaspy JA, Aronson WJ. PMID: 16899616; PMCID: PMC3410648.
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PubMed Mentions:
73 Fields:
Translation:
HumansAnimalsCells
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Potential clinical utility of high-density lipoprotein-mimetic peptides. Curr Opin Lipidol. 2006 Aug; 17(4):440-4.
Navab M, Anantharamaiah GM, Reddy ST, Van Lenten BJ, Datta G, Garber D, Fogelman AM. PMID: 16832169.
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PubMed Mentions:
8 Fields:
Translation:
Animals
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Understanding changes in high density lipoproteins during the acute phase response. Arterioscler Thromb Vasc Biol. 2006 Aug; 26(8):1687-8.
Van Lenten BJ, Reddy ST, Navab M, Fogelman AM. PMID: 16857958.
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PubMed Mentions:
20 Fields:
Translation:
HumansAnimalsCells
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D-4F decreases brain arteriole inflammation and improves cognitive performance in LDL receptor-null mice on a Western diet. J Lipid Res. 2006 Oct; 47(10):2148-60.
Buga GM, Frank JS, Mottino GA, Hendizadeh M, Hakhamian A, Tillisch JH, Reddy ST, Navab M, Anantharamaiah GM, Ignarro LJ, Fogelman AM. PMID: 16835442.
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PubMed Mentions:
40 Fields:
Translation:
Animals
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Synthetic peptides: managing lipid disorders. Curr Opin Lipidol. 2006 Jun; 17(3):233-7.
Anantharamaiah G, Navab M, Reddy ST, Garber DW, Datta G, Gupta H, White CR, Handattu SP, Palgunachari MN, Chaddha M, Mishra VK, Segrest JP, Fogelman AM. PMID: 16680027.
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PubMed Mentions:
5 Fields:
Translation:
HumansAnimals
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Oral amphipathic peptides as therapeutic agents. Expert Opin Investig Drugs. 2006 Jan; 15(1):13-21.
Reddy ST, Anantharamaiah GM, Navab M, Hama S, Hough G, Grijalva V, Garber DW, Datta G, Fogelman AM. PMID: 16370930.
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PubMed Mentions:
11 Fields:
Translation:
HumansAnimalsCells
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Characterization of serum biomarkers for detection of early stage ovarian cancer. Proteomics. 2005 Nov; 5(17):4589-96.
Kozak KR, Su F, Whitelegge JP, Faull K, Reddy S, Farias-Eisner R. PMID: 16237736.
View in:
PubMed Mentions:
105 Fields:
Translation:
Humans
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Oxidized phospholipids mediate occludin expression and phosphorylation in vascular endothelial cells. Am J Physiol Heart Circ Physiol. 2006 Feb; 290(2):H674-83.
DeMaio L, Rouhanizadeh M, Reddy S, Sevanian A, Hwang J, Hsiai TK. PMID: 16172163.
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PubMed Mentions:
27 Fields:
Translation:
AnimalsCells
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Oral small peptides render HDL antiinflammatory in mice and monkeys and reduce atherosclerosis in ApoE null mice. Circ Res. 2005 Sep 16; 97(6):524-32.
Navab M, Anantharamaiah GM, Reddy ST, Hama S, Hough G, Frank JS, Grijalva VR, Ganesh VK, Mishra VK, Palgunachari MN, Fogelman AM. PMID: 16100046.
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PubMed Mentions:
24 Fields:
Translation:
HumansAnimalsCells
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An oral apoJ peptide renders HDL antiinflammatory in mice and monkeys and dramatically reduces atherosclerosis in apolipoprotein E-null mice. Arterioscler Thromb Vasc Biol. 2005 Sep; 25(9):1932-7.
Navab M, Anantharamaiah GM, Reddy ST, Van Lenten BJ, Wagner AC, Hama S, Hough G, Bachini E, Garber DW, Mishra VK, Palgunachari MN, Fogelman AM. PMID: 15961700.
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PubMed Mentions:
44 Fields:
Translation:
HumansAnimalsCells
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D-4F and statins synergize to render HDL antiinflammatory in mice and monkeys and cause lesion regression in old apolipoprotein E-null mice. Arterioscler Thromb Vasc Biol. 2005 Jul; 25(7):1426-32.
Navab M, Anantharamaiah GM, Hama S, Hough G, Reddy ST, Frank JS, Garber DW, Handattu S, Fogelman AM. PMID: 15845909.
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PubMed Mentions:
65 Fields:
Translation:
AnimalsCells
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Apolipoprotein A-I mimetic peptides. Arterioscler Thromb Vasc Biol. 2005 Jul; 25(7):1325-31.
Navab M, Anantharamaiah GM, Reddy ST, Hama S, Hough G, Grijalva VR, Yu N, Ansell BJ, Datta G, Garber DW, Fogelman AM. PMID: 15831812.
View in:
PubMed Mentions:
98 Fields:
Translation:
HumansAnimalsCells
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The paraoxonase gene family and atherosclerosis. Free Radic Biol Med. 2005 Jan 15; 38(2):153-63.
Ng CJ, Shih DM, Hama SY, Villa N, Navab M, Reddy ST. PMID: 15607899.
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PubMed Mentions:
80 Fields:
Translation:
HumansAnimalsCells
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The double jeopardy of HDL. Ann Med. 2005; 37(3):173-8.
Navab M, Ananthramaiah GM, Reddy ST, Van Lenten BJ, Ansell BJ, Hama S, Hough G, Bachini E, Grijalva VR, Wagner AC, Shaposhnik Z, Fogelman AM. PMID: 16019715.
View in:
PubMed Mentions:
49 Fields:
Translation:
HumansAnimals
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Human apolipoprotein A-I and A-I mimetic peptides: potential for atherosclerosis reversal. Curr Opin Lipidol. 2004 Dec; 15(6):645-9.
Navab M, Anantharamaiah GM, Reddy ST, Van Lenten BJ, Datta G, Garber D, Fogelman AM. PMID: 15529023.
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PubMed Mentions:
24 Fields:
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HumansAnimalsCells
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Targeting c-Mpl for revival of human immunodeficiency virus type 1-induced hematopoietic inhibition when CD34+ progenitor cells are re-engrafted into a fresh stromal microenvironment in vivo. J Virol. 2004 Oct; 78(20):11385-92.
Koka PS, Kitchen CM, Reddy ST. PMID: 15452260; PMCID: PMC521839.
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PubMed Mentions:
8 Fields:
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HumansAnimalsCells
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Potential role for mitogen-activated protein kinase phosphatase-1 in the development of atherosclerotic lesions in mouse models. Arterioscler Thromb Vasc Biol. 2004 Sep; 24(9):1676-81.
Reddy ST, Nguyen JT, Grijalva V, Hough G, Hama S, Navab M, Fogelman AM. PMID: 15242861.
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PubMed Mentions:
16 Fields:
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AnimalsCells
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Cytopenias in HIV infection: mechanisms and alleviation of hematopoietic inhibition. Curr HIV Res. 2004 Jul; 2(3):275-82.
Koka PS, Reddy ST. PMID: 15279591.
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24 Fields:
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HumansAnimalsCells
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Oral D-4F causes formation of pre-beta high-density lipoprotein and improves high-density lipoprotein-mediated cholesterol efflux and reverse cholesterol transport from macrophages in apolipoprotein E-null mice. Circulation. 2004 Jun 29; 109(25):3215-20.
Navab M, Anantharamaiah GM, Reddy ST, Hama S, Hough G, Grijalva VR, Wagner AC, Frank JS, Datta G, Garber D, Fogelman AM. PMID: 15197147.
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PubMed Mentions:
133 Fields:
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HumansAnimalsCells
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Oxidized phospholipids increase interleukin 8 (IL-8) synthesis by activation of the c-src/signal transducers and activators of transcription (STAT)3 pathway. J Biol Chem. 2004 Jul 16; 279(29):30175-81.
Yeh M, Gharavi NM, Choi J, Hsieh X, Reed E, Mouillesseaux KP, Cole AL, Reddy ST, Berliner JA. PMID: 15143062.
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PubMed Mentions:
46 Fields:
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HumansCells
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The oxidation hypothesis of atherogenesis: the role of oxidized phospholipids and HDL. J Lipid Res. 2004 Jun; 45(6):993-1007.
Navab M, Ananthramaiah GM, Reddy ST, Van Lenten BJ, Ansell BJ, Fonarow GC, Vahabzadeh K, Hama S, Hough G, Kamranpour N, Berliner JA, Lusis AJ, Fogelman AM. PMID: 15060092.
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PubMed Mentions:
202 Fields:
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HumansAnimalsCells
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Apparent paradox of low-fat "healthy" diets increasing plasma levels of oxidized low-density lipoprotein and lipoprotein(a). Arterioscler Thromb Vasc Biol. 2004 Mar; 24(3):392-3.
Navab M, Reddy ST, Van Lenten BJ, Fogelman AM. PMID: 15003971.
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HumansAnimalsCells
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Inflammatory/antiinflammatory properties of high-density lipoprotein distinguish patients from control subjects better than high-density lipoprotein cholesterol levels and are favorably affected by simvastatin treatment. Circulation. 2003 Dec 02; 108(22):2751-6.
Ansell BJ, Navab M, Hama S, Kamranpour N, Fonarow G, Hough G, Rahmani S, Mottahedeh R, Dave R, Reddy ST, Fogelman AM. PMID: 14638544.
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PubMed Mentions:
223 Fields:
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HumansCellsCTClinical Trials
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Identification of biomarkers for ovarian cancer using strong anion-exchange ProteinChips: potential use in diagnosis and prognosis. Proc Natl Acad Sci U S A. 2003 Oct 14; 100(21):12343-8.
Kozak KR, Amneus MW, Pusey SM, Su F, Luong MN, Luong SA, Reddy ST, Farias-Eisner R. PMID: 14523236; PMCID: PMC218760.
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PubMed Mentions:
66 Fields:
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Humans
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Human apolipoprotein AI mimetic peptides for the treatment of atherosclerosis. Curr Opin Investig Drugs. 2003 Sep; 4(9):1100-4.
Navab M, Anantharamaiah GM, Reddy ST, Van Lenten BJ, Hough G, Wagner A, Nakamura K, Garber DW, Datta G, Segrest JP, Hama S, Fogelman AM. PMID: 14582455.
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PubMed Mentions:
11 Fields:
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HumansAnimals
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Differential effects of prostaglandin derived from omega-6 and omega-3 polyunsaturated fatty acids on COX-2 expression and IL-6 secretion. Proc Natl Acad Sci U S A. 2003 Feb 18; 100(4):1751-6.
Bagga D, Wang L, Farias-Eisner R, Glaspy JA, Reddy ST. PMID: 12578976; PMCID: PMC149905.
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PubMed Mentions:
205 Fields:
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AnimalsCells
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17-epiestriol, an estrogen metabolite, is more potent than estradiol in inhibiting vascular cell adhesion molecule 1 (VCAM-1) mRNA expression. J Biol Chem. 2003 Apr 04; 278(14):11746-52.
Mukherjee TK, Nathan L, Dinh H, Reddy ST, Chaudhuri G. PMID: 12547825.
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PubMed Mentions:
14 Fields:
Translation:
HumansCells
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Prostaglandin H synthase 2 variant (Val511Ala) in African Americans may reduce the risk for colorectal neoplasia. Cancer Epidemiol Biomarkers Prev. 2002 Nov; 11(11):1305-15.
Lin HJ, Lakkides KM, Keku TO, Reddy ST, Louie AD, Kau IH, Zhou H, Gim JS, Ma HL, Matthies CF, Dai A, Huang HF, Materi AM, Lin JH, Frankl HD, Lee ER, Hardy SI, Herschman HR, Henderson BE, Kolonel LN, Le Marchand L, Garavito RM, Sandler RS, Haile RW, Smith WL. PMID: 12433707.
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PubMed Mentions:
26 Fields:
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Humans
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ATP-binding cassette transporter 1 participates in LDL oxidation by artery wall cells. Arterioscler Thromb Vasc Biol. 2002 Nov 01; 22(11):1877-83.
Reddy ST, Hama S, Ng C, Grijalva V, Navab M, Fogelman AM. PMID: 12426219.
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PubMed Mentions:
13 Fields:
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HumansCells
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Diesel exhaust particle extracts and associated polycyclic aromatic hydrocarbons inhibit Cox-2-dependent prostaglandin synthesis in murine macrophages and fibroblasts. J Biol Chem. 2002 Oct 18; 277(42):39259-65.
Rudra-Ganguly N, Reddy ST, Korge P, Herschman HR. PMID: 12163478.
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PubMed Mentions:
3 Fields:
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AnimalsCellsPHPublic Health
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Urokinase plasminogen activator receptor: Prognostic biomarker for endometrial cancer. Proc Natl Acad Sci U S A. 2002 Aug 06; 99(16):10647-52.
Memarzadeh S, Kozak KR, Chang L, Natarajan S, Shintaku P, Reddy ST, Farias-Eisner R, Memarzedeh S. PMID: 12130664; PMCID: PMC125001.
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PubMed Mentions:
24 Fields:
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Humans
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Identification of genes induced by oxidized phospholipids in human aortic endothelial cells. Vascul Pharmacol. 2002 Apr; 38(4):211-8.
Reddy ST, Grijalva V, Ng C, Hassan K, Hama S, Mottahedeh R, Wadleigh DJ, Navab M, Fogelman AM. PMID: 12449017.
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PubMed Mentions:
9 Fields:
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HumansCells
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Human paraoxonase-3 is an HDL-associated enzyme with biological activity similar to paraoxonase-1 protein but is not regulated by oxidized lipids. Arterioscler Thromb Vasc Biol. 2001 Apr; 21(4):542-7.
Reddy ST, Wadleigh DJ, Grijalva V, Ng C, Hama S, Gangopadhyay A, Shih DM, Lusis AJ, Navab M, Fogelman AM. PMID: 11304470.
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PubMed Mentions:
106 Fields:
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HumansAnimalsCells
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Mitogen-activated protein kinase phosphatase 1 activity is necessary for oxidized phospholipids to induce monocyte chemotactic activity in human aortic endothelial cells. J Biol Chem. 2001 May 18; 276(20):17030-5.
Reddy S, Hama S, Grijalva V, Hassan K, Mottahedeh R, Hough G, Wadleigh DJ, Navab M, Fogelman AM. PMID: 11278958.
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PubMed Mentions:
14 Fields:
Translation:
HumansCells