Srinivasa T Reddy

Title(s)Professor-in-Residence, Medicine
SchoolMedicine
Emailsreddy@mednet.ucla.edu
ORCID ORCID Icon0000-0003-2959-9531 Additional info
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    Other Positions
    Title(s)Professor-in-Residence, Molecular and Medical Pharmacology


    Collapse Biography 
    Collapse Education and Training
    Osmania University, Hyderabad, A.P., IndiaB.Sc (Hons)06/1984Chemistry
    Roorkee University , Roorkee, U.P., IndiaM. Sc (Hons)06/1986Biological Sciences
    UC Berkeley, Berkeley CAPhD06/1992Comparative Biochemistry
    University of California Los Angeles, Los angeles, CAPost-doctoral training04/1997Cell and Molecular Biology
    Collapse Awards and Honors
    Roorkee University1984  - 1986Gold Medal
    UCLA2000  - 2001George Popjak Award

    Collapse Overview 

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Intestinal IFNα4 promotes 15-HETE diet-induced pulmonary hypertension. Respir Res. 2024 Nov 28; 25(1):419. Ruffenach G, Medzikovic L, Aryan L, Sun W, Lertpanit L, O'Connor E, Dehghanitafti A, Hatamnejad MR, Li M, Reddy ST, Eghbali M. PMID: 39609844; PMCID: PMC11606228.
      View in: PubMed   Mentions:
    2. Disease response in rheumatoid arthritis across four biologic therapies associates with improvement in paraoxonase-1 activity and oxylipins. RMD Open. 2024 Oct 26; 10(4). Razmjou AA, Kremer JM, Pappas DA, Curtis JR, Wang J, Shahbazian A, Elashoff DA, Guo R, Meriwether D, Sulaiman D, O'Connor E, Reddy ST, Charles-Schoeman C. PMID: 39461874; PMCID: PMC11529732.
      View in: PubMed   Mentions: Translation:Humans
    3. Evidence further linking the intestine to cardiovascular disease. Curr Opin Lipidol. 2024 Oct 01; 35(5):223-227. Sulaiman D, Reddy ST, Fogelman AM. PMID: 39073599; PMCID: PMC11377042.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimals
    4. Ambient Particulate Matter Induces In Vitro Toxicity to Intestinal Epithelial Cells without Exacerbating Acute Colitis Induced by Dextran Sodium Sulfate or 2,4,6-Trinitrobenzenesulfonic Acid. Int J Mol Sci. 2024 Jun 29; 25(13). Chang C, Louie A, Zhou Y, Gupta R, Liang F, Xanthou G, Ereso J, Koletic C, Yang JC, Sedighian F, Lagishetty V, Arias-Jayo N, Altuwayjiri A, Tohidi R, Navab M, Reddy ST, Sioutas C, Hsiai T, Araujo JA, Jacobs JP. PMID: 39000289; PMCID: PMC11241079.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    5. Non-Invasive Detection of Early-Stage Fatty Liver Disease via an On-Skin Impedance Sensor and Attention-Based Deep Learning. Adv Sci (Weinh). 2024 Aug; 11(31):e2400596. Wang K, Margolis S, Cho JM, Wang S, Arianpour B, Jabalera A, Yin J, Hong W, Zhang Y, Zhao P, Zhu E, Reddy S, Hsiai TK. PMID: 38887178; PMCID: PMC11336938.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimals
    6. The Lipid Intensive Drug Therapy for Sepsis Phase II Pilot Clinical Trial. Crit Care Med. 2024 Aug 01; 52(8):1183-1193. Guirgis FW, Black LP, Henson M, Bertrand A, DeVos E, Ferreira J, Gao H, Wu SS, Leeuwenburgh C, Moldawer L, Moore F, Reddy ST. PMID: 38488429.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCTClinical Trials
    7. Lipidomic changes in a novel sepsis outcome-based analysis reveals potent pro-inflammatory and pro-resolving signaling lipids. Clin Transl Sci. 2024 03; 17(3):e13745. Sulaiman D, Wu D, Black LP, Williams KJ, Graim K, Datta S, Reddy ST, Guirgis FW. PMID: 38488489; PMCID: PMC10941572.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    8. Exercise mitigates flow recirculation and activates metabolic transducer SCD1 to catalyze vascular protective metabolites. Sci Adv. 2024 Feb 16; 10(7):eadj7481. Cavallero S, Roustaei M, Satta S, Cho JM, Phan H, Baek KI, Blázquez-Medela AM, Gonzalez-Ramos S, Vu K, Park SK, Yokota T, Sumner J, Mack JJ, Sigmund CD, Reddy ST, Li R, Hsiai TK. PMID: 38354249; PMCID: PMC10866565.
      View in: PubMed   Mentions: 2     Fields:    Translation:Animals
    9. Subchronic inhalation exposure to ultrafine particulate matter alters the intestinal microbiome in various mouse models. Environ Res. 2024 May 01; 248:118242. Chang C, Gupta R, Sedighian F, Louie A, Gonzalez DM, Le C, Cho JM, Park SK, Castellanos J, Ting TW, Dong TS, Arias-Jayo N, Lagishetty V, Navab M, Reddy S, Sioutas C, Hsiai T, Jacobs JP, Araujo JA. PMID: 38242419.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsPHPublic Health
    10. TRENDS IN CHOLESTEROL AND LIPOPROTEINS ARE ASSOCIATED WITH ACUTE RESPIRATORY DISTRESS SYNDROME INCIDENCE AND DEATH AMONG SEPSIS PATIENTS. Shock. 2024 Feb 01; 61(2):260-265. Black LP, Hopson C, Barker G, Munson T, Henson M, Bertrand A, Daly-Crews K, Reddy ST, Guirgis FW. PMID: 38407817; PMCID: PMC10957110.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    11. Correction to: Suppressed paraoxonase-1 activity associates with elevated oxylipins and the presence of small airways disease in patients with rheumatoid arthritis. Clin Rheumatol. 2023 Nov; 42(11):3175. Razmjou AA, Wang JM, Shahbazian A, Reddy S, Charles-Schoeman C. PMID: 37707640; PMCID: PMC10587016.
      View in: PubMed   Mentions:    Fields:    
    12. Paraoxonase 2 Deficiency Causes Mitochondrial Dysfunction in Retinal Pigment Epithelial Cells and Retinal Degeneration in Mice. Antioxidants (Basel). 2023 Sep 30; 12(10). Sreekumar PG, Su F, Spee C, Hong E, Komirisetty R, Araujo E, Nusinowitz S, Reddy ST, Kannan R. PMID: 37891899; PMCID: PMC10604559.
      View in: PubMed   Mentions: 3  
    13. Lipid Mediators and Cytokines/Chemokines Display Differential Profiles in Severe versus Mild/Moderate COVID-19 Patients. Int J Mol Sci. 2023 Aug 22; 24(17). Ravindran R, O'Connor E, Gupta A, Luciw PA, Khan AI, Dorreh N, Chiang K, Ikram A, Reddy S. PMID: 37685858; PMCID: PMC10488250.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    14. Integrating 4-D light-sheet fluorescence microscopy and genetic zebrafish system to investigate ambient pollutants-mediated toxicity. Sci Total Environ. 2023 Dec 01; 902:165947. Gonzalez-Ramos S, Wang J, Cho JM, Zhu E, Park SK, In JG, Reddy ST, Castillo EF, Campen MJ, Hsiai TK. PMID: 37543337; PMCID: PMC10659062.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsPHPublic Health
    15. The multiple roles of lysophosphatidic acid in vascular disease and atherosclerosis. Curr Opin Lipidol. 2023 10 01; 34(5):196-200. Chattopadhyay A, Reddy ST, Fogelman AM. PMID: 37497844.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    16. DHCR7 Expression Predicts Poor Outcomes and Mortality From Sepsis. Crit Care Explor. 2023 Jun; 5(6):e0929. Guirgis FW, Jacob V, Wu D, Henson M, Daly-Crews K, Hopson C, Black LP, DeVos EL, Sulaiman D, Labilloy G, Brusko TM, Shavit JA, Bertrand A, Feldhammer M, Baskovich B, Graim K, Datta S, Reddy ST. PMID: 37332366; PMCID: PMC10270496.
      View in: PubMed   Mentions: 3  
    17. Stability Characterization of the Novel Anti-Cancer HM-10/10 HDL-Mimetic Peptide. Int J Mol Sci. 2023 Jun 13; 24(12). Dempsey MP, Andersen KE, Wells BM, Taylor MA, Cashman CL, Conrad LB, Kearney CA, Conklin MB, Via ER, Doe EM, Komirisetty R, Dearborn S, Reddy ST, Farias-Eisner R. PMID: 37373203; PMCID: PMC10298982.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    18. Exercise Mitigates Flow Recirculation and Activates Mechanosensitive Transcriptome to Uncover Endothelial SCD1-Catalyzed Anti-Inflammatory Metabolites. bioRxiv. 2023 May 03. Cavallero S, Roustaei M, Satta S, Cho JM, Phan H, Baek KI, Blázquez-Medela AM, Gonzalez-Ramos S, Vu K, Park SK, Yokota T, Sumner JA, Mack JJ, Sigmund CD, Reddy ST, Li R, Hsiai TK. PMID: 37205360; PMCID: PMC10187200.
      View in: PubMed   Mentions:
    19. Editorial: Pathogenesis in progenitor cells: epigenetics and external influences. Front Cell Dev Biol. 2023; 11:1205372. Koka PS, Reddy ST. PMID: 37181749; PMCID: PMC10167951.
      View in: PubMed   Mentions: 1  
    20. Vutiglabridin Modulates Paraoxonase 1 and Ameliorates Diet-Induced Obesity in Hyperlipidemic Mice. Biomolecules. 2023 04 18; 13(4). Sulaiman D, Choi LS, Lee HM, Shin J, Kim DH, Lee KW, Eftekhari P, Quartier A, Park HS, Reddy ST. PMID: 37189434; PMCID: PMC10135725.
      View in: PubMed   Mentions:    Fields:    Translation:Animals
    21. Role of enterocyte Enpp2 and autotaxin in regulating lipopolysaccharide levels, systemic inflammation, and atherosclerosis. J Lipid Res. 2023 05; 64(5):100370. Chattopadhyay A, Mukherjee P, Sulaiman D, Wang H, Girjalva V, Dorreh N, Jacobs JP, Delk S, Moolenaar WH, Navab M, Reddy ST, Fogelman AM. PMID: 37059333; PMCID: PMC10200992.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    22. DHCR7 Expression Predicts Poor Outcomes and Mortality from Sepsis. Res Sq. 2023 Jan 30. Guirgis FW, Jacob V, Wu D, Henson M, Daly-Crews K, Hopson C, Black LP, DeVos EL, Sulaiman D, Labilloy G, Brusko TM, Shavit JA, Bertrand A, Feldhammer M, Baskovich B, Graim K, Datta S, Reddy ST. PMID: 36778468; PMCID: PMC9915766.
      View in: PubMed   Mentions:
    23. Oxidative Stress and Lipid Accumulation Augments Cell Death in LDLR-Deficient RPE Cells and Ldlr-/- Mice. Cells. 2022 12 22; 12(1). Sreekumar PG, Su F, Spee C, Araujo E, Nusinowitz S, Reddy ST, Kannan R. PMID: 36611838; PMCID: PMC9818299.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansAnimals
    24. Suppressed paraoxonase-1 activity associates with elevated oxylipins and the presence of small airways disease in patients with rheumatoid arthritis. Clin Rheumatol. 2023 Jan; 42(1):75-82. Razmjou AA, Wang JM, Shahbazian A, Reddy S, Charles-Schoeman C. PMID: 36138190; PMCID: PMC9823017.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    25. The role of gut-derived oxidized lipids and bacterial lipopolysaccharide in systemic inflammation and atherosclerosis. Curr Opin Lipidol. 2022 10 01; 33(5):277-282. Wang H, Reddy ST, Fogelman AM. PMID: 35979993; PMCID: PMC9581106.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    26. Abnormal paraoxonase-1 (PON1) enzyme activity in idiopathic inflammatory myopathies. Rheumatology (Oxford). 2022 05 30; 61(6):2512-2523. Bae SS, Shahbazian A, Wang J, Golub I, Oganesian B, Dowd T, Vayngortin B, Wang R, Elashoff D, Reddy ST, Charles-Schoeman C. PMID: 34698804; PMCID: PMC9308379.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    27. Differential Peripheral Blood Glycoprotein Profiles in Symptomatic and Asymptomatic COVID-19. Viruses. 2022 03 07; 14(3). Pickering C, Zhou B, Xu G, Rice R, Ramachandran P, Huang H, Pham TD, Schapiro JM, Cong X, Chakraborty S, Edwards K, Reddy ST, Guirgis F, Wang TT, Serie D, Lindpaintner K. PMID: 35336960; PMCID: PMC8951729.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    28. Ramatroban for chemoprophylaxis and treatment of COVID-19: David takes on Goliath. Expert Opin Ther Targets. 2022 01; 26(1):13-28. Chiang KC, Rizk JG, Nelson DJ, Krishnamurti L, Subbian S, Imig JD, Khan I, Reddy ST, Gupta A. PMID: 35068281; PMCID: PMC10119876.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimalsCells
    29. Macrophage COX2 Mediates Efferocytosis, Resolution Reprogramming, and Intestinal Epithelial Repair. Cell Mol Gastroenterol Hepatol. 2022; 13(4):1095-1120. Meriwether D, Jones AE, Ashby JW, Solorzano-Vargas RS, Dorreh N, Noori S, Grijalva V, Ball AB, Semis M, Divakaruni AS, Mack JJ, Herschman HR, Martin MG, Fogelman AM, Reddy ST. PMID: 35017061; PMCID: PMC8873959.
      View in: PubMed   Mentions: 12     Fields:    Translation:AnimalsCells
    30. ApoA-I mimetics reduce systemic and gut inflammation in chronic treated HIV. PLoS Pathog. 2022 01; 18(1):e1010160. Daskou M, Mu W, Sharma M, Vasilopoulos H, Heymans R, Ritou E, Rezek V, Hamid P, Kossyvakis A, Sen Roy S, Grijalva V, Chattopadhyay A, Kitchen SG, Fogelman AM, Reddy ST, Kelesidis T. PMID: 34995311; PMCID: PMC8740974.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimals
    31. Mechanisms of RPE senescence and potential role of αB crystallin peptide as a senolytic agent in experimental AMD. Exp Eye Res. 2022 02; 215:108918. Sreekumar PG, Reddy ST, Hinton DR, Kannan R. PMID: 34986369; PMCID: PMC8923947.
      View in: PubMed   Mentions: 15     Fields:    Translation:Animals
    32. The ApoA-I mimetic peptide 4F attenuates in vitro replication of SARS-CoV-2, associated apoptosis, oxidative stress and inflammation in epithelial cells. Virulence. 2021 12; 12(1):2214-2227. Kelesidis T, Madhav S, Petcherski A, Cristelle H, O'Connor E, Hultgren NW, Ritou E, Williams DS, Shirihai OS, Reddy ST. PMID: 34494942; PMCID: PMC8437485.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansAnimalsCells
    33. Oxidized phospholipids cause changes in jejunum mucus that induce dysbiosis and systemic inflammation. J Lipid Res. 2022 Jan; 63(1):100153. Mukherjee P, Chattopadhyay A, Grijalva V, Dorreh N, Lagishetty V, Jacobs JP, Clifford BL, Vallim T, Mack JJ, Navab M, Reddy ST, Fogelman AM. PMID: 34808192; PMCID: PMC8953663.
      View in: PubMed   Mentions: 5     Fields:    Translation:AnimalsCells
    34. HDL and persistent inflammation immunosuppression and catabolism syndrome. Curr Opin Lipidol. 2021 10 01; 32(5):315-322. Barker G, Winer JR, Guirgis FW, Reddy S. PMID: 34374677; PMCID: PMC8416792.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    35. A hypolipoprotein sepsis phenotype indicates reduced lipoprotein antioxidant capacity, increased endothelial dysfunction and organ failure, and worse clinical outcomes. Crit Care. 2021 09 17; 25(1):341. Guirgis FW, Black LP, Henson M, Labilloy G, Smotherman C, Hopson C, Tfirn I, DeVos EL, Leeuwenburgh C, Moldawer L, Datta S, Brusko TM, Hester A, Bertrand A, Grijalva V, Arango-Esterhay A, Moore FA, Reddy ST. PMID: 34535154; PMCID: PMC8447561.
      View in: PubMed   Mentions: 15     Fields:    Translation:Humans
    36. Iron loading induces cholesterol synthesis and sensitizes endothelial cells to TNFα-mediated apoptosis. J Biol Chem. 2021 10; 297(4):101156. Fisher AL, Srole DN, Palaskas NJ, Meriwether D, Reddy ST, Ganz T, Nemeth E. PMID: 34480898; PMCID: PMC8463868.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansCells
    37. A Single LC-MS/MS Analysis to Quantify CoA Biosynthetic Intermediates and Short-Chain Acyl CoAs. Metabolites. 2021 Jul 21; 11(8). Jones AE, Arias NJ, Acevedo A, Reddy ST, Divakaruni AS, Meriwether D. PMID: 34436409; PMCID: PMC8401288.
      View in: PubMed   Mentions: 5  
    38. Lipid and lipoprotein predictors of functional outcomes and long-term mortality after surgical sepsis. Ann Intensive Care. 2021 May 20; 11(1):82. Guirgis FW, Leeuwenburgh C, Moldawer L, Ghita G, Black LP, Henson M, DeVos E, Holden D, Efron P, Reddy ST, Moore FA. PMID: 34018068; PMCID: PMC8136376.
      View in: PubMed   Mentions: 9  
    39. Lipid and Lipoprotein Dysregulation in Sepsis: Clinical and Mechanistic Insights into Chronic Critical Illness. J Clin Med. 2021 Apr 14; 10(8). Barker G, Leeuwenburgh C, Brusko T, Moldawer L, Reddy ST, Guirgis FW. PMID: 33920038; PMCID: PMC8071007.
      View in: PubMed   Mentions: 29  
    40. Novel Roles of Follistatin/Myostatin in Transforming Growth Factor-β Signaling and Adipose Browning: Potential for Therapeutic Intervention in Obesity Related Metabolic Disorders. Front Endocrinol (Lausanne). 2021; 12:653179. Pervin S, Reddy ST, Singh R. PMID: 33897620; PMCID: PMC8062757.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansAnimalsCells
    41. Apolipoprotein A-I mimetics attenuate macrophage activation in chronic treated HIV. AIDS. 2021 03 15; 35(4):543-553. Mu W, Sharma M, Heymans R, Ritou E, Rezek V, Hamid P, Kossyvakis A, Sen Roy S, Grijalva V, Chattopadhyay A, Papesh J, Meriwether D, Kitchen SG, Fogelman AM, Reddy ST, Kelesidis T. PMID: 33306550; PMCID: PMC8010648.
      View in: PubMed   Mentions: 9     Fields:    Translation:Animals
    42. PON2 subverts metabolic gatekeeper functions in B cells to promote leukemogenesis. Proc Natl Acad Sci U S A. 2021 02 16; 118(7). Pan L, Hong C, Chan LN, Xiao G, Malvi P, Robinson ME, Geng H, Reddy ST, Lee J, Khairnar V, Cosgun KN, Xu L, Kume K, Sadras T, Wang S, Wajapeyee N, Müschen M. PMID: 33531346; PMCID: PMC7896313.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimalsCells
    43. Endometriosis: A Malignant Fingerprint. J Cancer Res Ther Oncol. 2020 Apr; 8(2). DeAngelo C, Tarasiewicz MB, Strother A, Taggart H, Gray C, Shanahan M, Glowacki C, Khandalavala J, Talaska E, Kinnan A, Coté JJ, Edwards AP, Harper-Harrison G, Casey MJ, Hirai TL, Schultz S, Stines L, Vora R, Boudreau D, Burgart J, Shama M, Watson T, Strasheim L, Thompson R, Lawlor R, Joyce K, Magnuson CM, Driano J, Elger B, Lentino A, Driscoll M, Tidwell E, Sharma A, Walker SR, Jones G, Sharma P, Stessman H, Wu Y, Vadgama J, Chase D, Conrad L, Reddy ST, Farias-Eisner R. PMID: 33644256; PMCID: PMC7909468.
      View in: PubMed   Mentions: 3  
    44. Lipid intensive drug therapy for sepsis pilot: A Bayesian phase I clinical trial. J Am Coll Emerg Physicians Open. 2020 Dec; 1(6):1332-1340. Guirgis FW, Black LP, DeVos E, Henson M, Ferreira J, Miller T, Rosenthal M, Leeuwenburgh C, Kalynych C, Moldawer L, Jones L, Crandall M, Reddy ST, Gao H, Wu S, Moore F. PMID: 33392541; PMCID: PMC7771745.
      View in: PubMed   Mentions: 3  
    45. Apolipoprotein mimetics in cancer. Semin Cancer Biol. 2021 08; 73:158-168. Delk SC, Chattopadhyay A, Escola-Gil JC, Fogelman AM, Reddy ST. PMID: 33188891; PMCID: PMC8110614.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansAnimalsCells
    46. High- density lipoprotein function is abnormal in idiopathic inflammatory myopathies. Rheumatology (Oxford). 2020 11 01; 59(11):3515-3525. Bae SS, Lee YY, Shahbazian A, Wang J, Meriwether D, Golub I, Oganesian B, Dowd T, Reddy ST, Charles-Schoeman C. PMID: 32830270; PMCID: PMC7590404.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCells
    47. Suppression of inflammatory arthritis in human serum paraoxonase 1 transgenic mice. Sci Rep. 2020 10 08; 10(1):16848. Charles-Schoeman C, Wang J, Shahbazian A, Lee YY, Wang X, Grijalva V, Brahn E, Shih DM, Devarajan A, Montano C, Lusis AJ, Reddy ST. PMID: 33033318; PMCID: PMC7546628.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansAnimalsCells
    48. Ramatroban as a Novel Immunotherapy for COVID-19. J Mol Genet Med. 2020; 14(3). Gupta A, Kalantar-Zadeh K, Reddy ST. PMID: 32952595; PMCID: PMC7500620.
      View in: PubMed   Mentions: 13  
    49. Oral 15-Hydroxyeicosatetraenoic Acid Induces Pulmonary Hypertension in Mice by Triggering T Cell-Dependent Endothelial Cell Apoptosis. Hypertension. 2020 09; 76(3):985-996. Ruffenach G, O'Connor E, Vaillancourt M, Hong J, Cao N, Sarji S, Moazeni S, Papesh J, Grijalva V, Cunningham CM, Shu L, Chattopadhyay A, Tiwari S, Mercier O, Perros F, Umar S, Yang X, Gomes AV, Fogelman AM, Reddy ST, Eghbali M. PMID: 32713273; PMCID: PMC8008496.
      View in: PubMed   Mentions: 11     Fields:    Translation:AnimalsCells
    50. Quantitative and Qualitative Assessments of Cholesterol Association With Bacterial Infection Type in Sepsis and Septic Shock. J Intensive Care Med. 2021 Jul; 36(7):808-817. Black LP, Puskarich MA, Henson M, Miller T, Reddy ST, Fernandez R, Guirgis FW. PMID: 32578468; PMCID: PMC8061684.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    51. Bovine HDL and Dual Domain HDL-Mimetic Peptides Inhibit Tumor Development in Mice. J Cancer Res Ther Oncol. 2020; 8(1). Su F, Gm A, Palgunachari MN, White CR, Stessman H, Wu Y, Vadgama J, Pietras R, Nguyen D, Reddy ST, Farias-Eisner R. PMID: 32462055; PMCID: PMC7252215.
      View in: PubMed   Mentions: 4  
    52. Involvement of Low-Density Lipoprotein Receptor in the Pathogenesis of Pulmonary Hypertension. J Am Heart Assoc. 2020 01 21; 9(2):e012063. Umar S, Ruffenach G, Moazeni S, Vaillancourt M, Hong J, Cunningham C, Cao N, Navab S, Sarji S, Li M, Lee L, Fishbein G, Ardehali A, Navab M, Reddy ST, Eghbali M. PMID: 31914876; PMCID: PMC7033825.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansAnimalsCells
    53. A Novel HDL-Mimetic Peptide HM-10/10 Protects RPE and Photoreceptors in Murine Models of Retinal Degeneration. Int J Mol Sci. 2019 Sep 27; 20(19). Su F, Spee C, Araujo E, Barron E, Wang M, Ghione C, Hinton DR, Nusinowitz S, Kannan R, Reddy ST, Farias-Eisner R. PMID: 31569695; PMCID: PMC6801888.
      View in: PubMed   Mentions: 8     Fields:    Translation:AnimalsCells
    54. LIPid Intensive Drug therapy for Sepsis Pilot (LIPIDS-P): Phase I/II clinical trial protocol of lipid emulsion therapy for stabilising cholesterol levels in sepsis and septic shock. BMJ Open. 2019 09 18; 9(9):e029348. Guirgis FW, Black LP, Rosenthal MD, Henson M, Ferreira J, Leeuwenburgh C, Kalynych C, Moldawer LL, Miller T, Jones L, Crandall M, Reddy ST, Wu SS, Moore FA. PMID: 31537565; PMCID: PMC6756323.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansCTClinical Trials
    55. Histological hallmarks and role of Slug/PIP axis in pulmonary hypertension secondary to pulmonary fibrosis. EMBO Mol Med. 2019 09; 11(9):e10061. Ruffenach G, Umar S, Vaillancourt M, Hong J, Cao N, Sarji S, Moazeni S, Cunningham CM, Ardehali A, Reddy ST, Saggar R, Fishbein G, Eghbali M. PMID: 31468711; PMCID: PMC6728601.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansAnimalsCells
    56. HDL and LDL: Potential New Players in Breast Cancer Development. J Clin Med. 2019 Jun 14; 8(6). Cedó L, Reddy ST, Mato E, Blanco-Vaca F, Escolà-Gil JC. PMID: 31208017; PMCID: PMC6616617.
      View in: PubMed   Mentions: 70  
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    118. Anti-inflammatory and antioxidant properties of HDLs are impaired in type 2 diabetes. Diabetes. 2011 Oct; 60(10):2617-23. Morgantini C, Natali A, Boldrini B, Imaizumi S, Navab M, Fogelman AM, Ferrannini E, Reddy ST. PMID: 21852676; PMCID: PMC3178289.
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    119. Enhancement by LDL of transfer of L-4F and oxidized lipids to HDL in C57BL/6J mice and human plasma. J Lipid Res. 2011 Oct; 52(10):1795-809. Meriwether D, Imaizumi S, Grijalva V, Hough G, Vakili L, Anantharamaiah GM, Farias-Eisner R, Navab M, Fogelman AM, Reddy ST, Shechter I. PMID: 21804067; PMCID: PMC3173006.
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    120. Dysfunctional high-density lipoprotein and the potential of apolipoprotein A-1 mimetic peptides to normalize the composition and function of lipoproteins. Circ J. 2011; 75(7):1533-8. Imaizumi S, Navab M, Morgantini C, Charles-Schoeman C, Su F, Gao F, Kwon M, Ganapathy E, Meriwether D, Farias-Eisner R, Fogelman AM, Reddy ST. PMID: 21628835; PMCID: PMC3625624.
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    121. D-4F, an apoA-I mimetic peptide, inhibits proliferation and tumorigenicity of epithelial ovarian cancer cells by upregulating the antioxidant enzyme MnSOD. Int J Cancer. 2012 Mar 01; 130(5):1071-81. Ganapathy E, Su F, Meriwether D, Devarajan A, Grijalva V, Gao F, Chattopadhyay A, Anantharamaiah GM, Navab M, Fogelman AM, Reddy ST, Farias-Eisner R. PMID: 21425255; PMCID: PMC3248802.
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    122. Impaired hepatic insulin signalling in PON2-deficient mice: a novel role for the PON2/apoE axis on the macrophage inflammatory response. Biochem J. 2011 May 15; 436(1):91-100. Bourquard N, Ng CJ, Reddy ST. PMID: 21361875; PMCID: PMC3743554.
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    123. Optimization of microCT imaging and blood vessel diameter quantitation of preclinical specimen vasculature with radiopaque polymer injection medium. PLoS One. 2011 Apr 18; 6(4):e19099. Vasquez SX, Gao F, Su F, Grijalva V, Pope J, Martin B, Stinstra J, Masner M, Shah N, Weinstein DM, Farias-Eisner R, Reddy ST. PMID: 21533123; PMCID: PMC3078938.
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    124. Intestine may be a major site of action for the apoA-I mimetic peptide 4F whether administered subcutaneously or orally. J Lipid Res. 2011 Jun; 52(6):1200-1210. Navab M, Reddy ST, Anantharamaiah GM, Imaizumi S, Hough G, Hama S, Fogelman AM. PMID: 21444758; PMCID: PMC3090241.
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    125. HDL and cardiovascular disease: atherogenic and atheroprotective mechanisms. Nat Rev Cardiol. 2011 Apr; 8(4):222-32. Navab M, Reddy ST, Van Lenten BJ, Fogelman AM. PMID: 21304474.
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    126. L-5F, an apolipoprotein A-I mimetic, inhibits tumor angiogenesis by suppressing VEGF/basic FGF signaling pathways. Integr Biol (Camb). 2011 Apr; 3(4):479-89. Gao F, Vasquez SX, Su F, Roberts S, Shah N, Grijalva V, Imaizumi S, Chattopadhyay A, Ganapathy E, Meriwether D, Johnston B, Anantharamaiah GM, Navab M, Fogelman AM, Reddy ST, Farias-Eisner R. PMID: 21283904; PMCID: PMC3248743.
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    127. Chronic inflammatory disorders and accelerated atherosclerosis: chronic kidney disease. Curr Pharm Des. 2011; 17(1):17-20. Navab KD, Elboudwarej O, Gharif M, Yu J, Hama SY, Safarpour S, Hough GP, Vakili L, Reddy ST, Navab M, Vaziri ND. PMID: 21222643.
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    128. Treatment of patients with cardiovascular disease with L-4F, an apo-A1 mimetic, did not improve select biomarkers of HDL function. J Lipid Res. 2011 Feb; 52(2):361-73. Watson CE, Weissbach N, Kjems L, Ayalasomayajula S, Zhang Y, Chang I, Navab M, Hama S, Hough G, Reddy ST, Soffer D, Rader DJ, Fogelman AM, Schecter A. PMID: 21068008; PMCID: PMC3023557.
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    129. Human CYP2S1 metabolizes cyclooxygenase- and lipoxygenase-derived eicosanoids. Drug Metab Dispos. 2011 Feb; 39(2):180-90. Bui P, Imaizumi S, Beedanagari SR, Reddy ST, Hankinson O. PMID: 21068195; PMCID: PMC3033693.
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    130. Apolipoprotein A-I (apoA-I) and apoA-I mimetic peptides inhibit tumor development in a mouse model of ovarian cancer. Proc Natl Acad Sci U S A. 2010 Nov 16; 107(46):19997-20002. Su F, Kozak KR, Imaizumi S, Gao F, Amneus MW, Grijalva V, Ng C, Wagner A, Hough G, Farias-Eisner G, Anantharamaiah GM, Van Lenten BJ, Navab M, Fogelman AM, Reddy ST, Farias-Eisner R. PMID: 21041624; PMCID: PMC2993420.
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    131. Apolipoprotein A-I mimetic peptides prevent atherosclerosis development and reduce plaque inflammation in a murine model of diabetes. Diabetes. 2010 Dec; 59(12):3223-8. Morgantini C, Imaizumi S, Grijalva V, Navab M, Fogelman AM, Reddy ST. PMID: 20826564; PMCID: PMC2992786.
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    132. Paraoxonase 2 deficiency alters mitochondrial function and exacerbates the development of atherosclerosis. Antioxid Redox Signal. 2011 Feb 01; 14(3):341-51. Devarajan A, Bourquard N, Hama S, Navab M, Grijalva VR, Morvardi S, Clarke CF, Vergnes L, Reue K, Teiber JF, Reddy ST. PMID: 20578959; PMCID: PMC3011913.
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    133. Effect of different intravenous iron preparations on lymphocyte intracellular reactive oxygen species generation and subpopulation survival. BMC Nephrol. 2010 Aug 17; 11:16. Gupta A, Zhuo J, Zha J, Reddy S, Olp J, Pai A. PMID: 20716362; PMCID: PMC2933673.
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    134. L-4F differentially alters plasma levels of oxidized fatty acids resulting in more anti-inflammatory HDL in mice. Drug Metab Lett. 2010 Aug; 4(3):139-48. Imaizumi S, Grijalva V, Navab M, Van Lenten BJ, Wagner AC, Anantharamiah GM, Fogelman AM, Reddy ST. PMID: 20642447; PMCID: PMC3037264.
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    135. Mitogen-activated protein kinase phosphatase-1 deficiency decreases atherosclerosis in apolipoprotein E null mice by reducing monocyte chemoattractant protein-1 levels. Mol Genet Metab. 2010 Sep; 101(1):66-75. Imaizumi S, Grijalva V, Priceman S, Wu L, Su F, Farias-Eisner R, Hama S, Navab M, Fogelman AM, Reddy ST. PMID: 20619710; PMCID: PMC3037189.
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    136. Novel anti-inflammatory functions for endothelial and myeloid cyclooxygenase-2 in a new mouse model of Crohn's disease. Am J Physiol Gastrointest Liver Physiol. 2010 Jun; 298(6):G842-50. Watanabe J, Lin JA, Narasimha AJ, Shahbazian A, Ishikawa TO, Martin MG, Herschman HR, Reddy ST. PMID: 20299600; PMCID: PMC8875131.
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    137. Putative innate immunity of antiatherogenic paraoxanase-2 via STAT5 signal transduction in HIV-1 infection of hematopoietic TF-1 cells and in SCID-hu mice. J Stem Cells. 2010; 5(1):43-8. Yuan J, Devarajan A, Moya-Castro R, Zhang M, Evans S, Bourquard N, Dias P, Lacout C, Vainchenker W, Reddy ST, Koka PS. PMID: 20861927.
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    138. L-4F alters hyperlipidemic (but not healthy) mouse plasma to reduce platelet aggregation. Arterioscler Thromb Vasc Biol. 2010 Feb; 30(2):283-9. Buga GM, Navab M, Imaizumi S, Reddy ST, Yekta B, Hough G, Chanslor S, Anantharamaiah GM, Fogelman AM. PMID: 19965777; PMCID: PMC2818809.
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    139. HDL as a biomarker, potential therapeutic target, and therapy. Diabetes. 2009 Dec; 58(12):2711-7. Navab M, Anantharamaiah GM, Reddy ST, Van Lenten BJ, Fogelman AM. PMID: 19940234; PMCID: PMC2780869.
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    140. Absence of myeloid COX-2 attenuates acute inflammation but does not influence development of atherosclerosis in apolipoprotein E null mice. Arterioscler Thromb Vasc Biol. 2010 Feb; 30(2):260-8. Narasimha AJ, Watanabe J, Ishikawa TO, Priceman SJ, Wu L, Herschman HR, Reddy ST. PMID: 19926832; PMCID: PMC2859183.
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    141. Abnormal function of high-density lipoprotein is associated with poor disease control and an altered protein cargo in rheumatoid arthritis. Arthritis Rheum. 2009 Oct; 60(10):2870-9. Charles-Schoeman C, Watanabe J, Lee YY, Furst DE, Amjadi S, Elashoff D, Park G, McMahon M, Paulus HE, Fogelman AM, Reddy ST. PMID: 19790070; PMCID: PMC2828490.
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    142. Validation of serum biomarkers for detection of early- and late-stage endometrial cancer. Am J Obstet Gynecol. 2010 Jan; 202(1):73.e1-5. Farias-Eisner G, Su F, Robbins T, Kotlerman J, Reddy S, Farias-Eisner R. PMID: 19766980.
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    143. Structure and function of HDL mimetics. Arterioscler Thromb Vasc Biol. 2010 Feb; 30(2):164-8. Navab M, Shechter I, Anantharamaiah GM, Reddy ST, Van Lenten BJ, Fogelman AM. PMID: 19608977; PMCID: PMC2860541.
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    144. Hemoglobin and its scavenger protein haptoglobin associate with apoA-1-containing particles and influence the inflammatory properties and function of high density lipoprotein. J Biol Chem. 2009 Jul 03; 284(27):18292-301. Watanabe J, Grijalva V, Hama S, Barbour K, Berger FG, Navab M, Fogelman AM, Reddy ST. PMID: 19433579; PMCID: PMC2709397.
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    145. Validation of serum biomarkers for detection of early-stage ovarian cancer. Am J Obstet Gynecol. 2009 Jun; 200(6):639.e1-5. Nosov V, Su F, Amneus M, Birrer M, Robins T, Kotlerman J, Reddy S, Farias-Eisner R. PMID: 19285648.
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    146. Apolipoprotein A-I mimetic peptides. Curr Atheroscler Rep. 2009 Jan; 11(1):52-7. Van Lenten BJ, Wagner AC, Anantharamaiah GM, Navab M, Reddy ST, Buga GM, Fogelman AM. PMID: 19080728; PMCID: PMC2856617.
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    147. Paraoxonase 2 attenuates macrophage triglyceride accumulation via inhibition of diacylglycerol acyltransferase 1. J Lipid Res. 2009 May; 50(5):870-9. Rosenblat M, Coleman R, Reddy ST, Aviram M. PMID: 19091699; PMCID: PMC2666173.
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    148. Multiple indications for anti-inflammatory apolipoprotein mimetic peptides. Curr Opin Investig Drugs. 2008 Nov; 9(11):1157-62. Van Lenten BJ, Navab M, Anantharamaiah GM, Buga GM, Reddy ST, Fogelman AM. PMID: 18951294; PMCID: PMC2856620.
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    149. The role of dysfunctional HDL in atherosclerosis. J Lipid Res. 2009 Apr; 50 Suppl:S145-9. Navab M, Reddy ST, Van Lenten BJ, Anantharamaiah GM, Fogelman AM. PMID: 18955731; PMCID: PMC2674720.
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    150. Host-derived oxidized phospholipids and HDL regulate innate immunity in human leprosy. J Clin Invest. 2008 Aug; 118(8):2917-28. Cruz D, Watson AD, Miller CS, Montoya D, Ochoa MT, Sieling PA, Gutierrez MA, Navab M, Reddy ST, Witztum JL, Fogelman AM, Rea TH, Eisenberg D, Berliner J, Modlin RL. PMID: 18636118; PMCID: PMC2467381.
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    151. Is it just paraoxonase 1 or are other members of the paraoxonase gene family implicated in atherosclerosis? Curr Opin Lipidol. 2008 Aug; 19(4):405-8. Reddy ST, Devarajan A, Bourquard N, Shih D, Fogelman AM. PMID: 18607188.
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    152. The early detection of ovarian cancer: from traditional methods to proteomics. Can we really do better than serum CA-125? Am J Obstet Gynecol. 2008 Sep; 199(3):215-23. Nossov V, Amneus M, Su F, Lang J, Janco JM, Reddy ST, Farias-Eisner R. PMID: 18468571.
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    153. Apo A-1 mimetic peptides as atheroprotective agents in murine models. Curr Drug Targets. 2008 Mar; 9(3):204-9. Navab M, Anantharamaiah GM, Reddy ST, Van Lenten BJ, Fogelman AM. PMID: 18336238.
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    154. Validation of candidate serum ovarian cancer biomarkers for early detection. Biomark Insights. 2007 Oct 16; 2:369-75. Su F, Lang J, Kumar A, Ng C, Hsieh B, Suchard MA, Reddy ST, Farias-Eisner R. PMID: 19662218; PMCID: PMC2717832.
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    155. D-4F reduces EO6 immunoreactivity, SREBP-1c mRNA levels, and renal inflammation in LDL receptor-null mice fed a Western diet. J Lipid Res. 2008 Jan; 49(1):192-205. Buga GM, Frank JS, Mottino GA, Hakhamian A, Narasimha A, Watson AD, Yekta B, Navab M, Reddy ST, Anantharamaiah GM, Fogelman AM. PMID: 17925450.
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    156. High-density lipoprotein: antioxidant and anti-inflammatory properties. Curr Atheroscler Rep. 2007 Sep; 9(3):244-8. Navab M, Yu R, Gharavi N, Huang W, Ezra N, Lotfizadeh A, Anantharamaiah GM, Alipour N, Van Lenten BJ, Reddy ST, Marelli D. PMID: 18241620.
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    157. Lipoprotein inflammatory properties and serum amyloid A levels but not cholesterol levels predict lesion area in cholesterol-fed rabbits. J Lipid Res. 2007 Nov; 48(11):2344-53. Van Lenten BJ, Wagner AC, Navab M, Anantharamaiah GM, Hama S, Reddy ST, Fogelman AM. PMID: 17693626.
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    158. Characterization of the rat urokinase plasminogen activator receptor promoter in PC12 cells. J Neurosci Res. 2007 Jul; 85(9):1952-8. Su F, Kozak KR, Herschman H, Reddy ST, Farias-Eisner R. PMID: 17455298.
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    159. Structural requirements for antioxidative and anti-inflammatory properties of apolipoprotein A-I mimetic peptides. J Lipid Res. 2007 Sep; 48(9):1915-23. Anantharamaiah GM, Mishra VK, Garber DW, Datta G, Handattu SP, Palgunachari MN, Chaddha M, Navab M, Reddy ST, Segrest JP, Fogelman AM. PMID: 17570869.
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    160. Differential association of hemoglobin with proinflammatory high density lipoproteins in atherogenic/hyperlipidemic mice. A novel biomarker of atherosclerosis. J Biol Chem. 2007 Aug 10; 282(32):23698-707. Watanabe J, Chou KJ, Liao JC, Miao Y, Meng HH, Ge H, Grijalva V, Hama S, Kozak K, Buga G, Whitelegge JP, Lee TD, Farias-Eisner R, Navab M, Fogelman AM, Reddy ST. PMID: 17556366.
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    161. Effects of high-dose atorvastatin on antiinflammatory properties of high density lipoprotein in patients with rheumatoid arthritis: a pilot study. J Rheumatol. 2007 Jul; 34(7):1459-64. Charles-Schoeman C, Khanna D, Furst DE, McMahon M, Reddy ST, Fogelman AM, Paulus HE, Park GS, Gong T, Ansell BJ. PMID: 17552046.
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    162. Peptide Mimetics of Apolipoproteins Improve HDL Function. J Clin Lipidol. 2007 May; 1(2):142-7. Navab M, Anantharamaiah GM, Reddy ST, Van Lenten BJ, Buga GM, Fogelman AM. PMID: 18449337; PMCID: PMC2130772.
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    163. Atherogenic diet causes lethal ileo-ceco-colitis in cyclooxygenase-2 deficient mice. Prostaglandins Other Lipid Mediat. 2007 Nov; 84(3-4):98-107. Lin JA, Watanabe J, Rozengurt N, Narasimha A, Martin MG, Wang J, Braun J, Langenbach R, Reddy ST. PMID: 17991612; PMCID: PMC2701900.
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    164. Adenovirus-mediated expression of human paraoxonase 3 protects against the progression of atherosclerosis in apolipoprotein E-deficient mice. Arterioscler Thromb Vasc Biol. 2007 Jun; 27(6):1368-74. Ng CJ, Bourquard N, Hama SY, Shih D, Grijalva VR, Navab M, Fogelman AM, Reddy ST. PMID: 17446441.
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    165. Decreased obesity and atherosclerosis in human paraoxonase 3 transgenic mice. Circ Res. 2007 Apr 27; 100(8):1200-7. Shih DM, Xia YR, Wang XP, Wang SS, Bourquard N, Fogelman AM, Lusis AJ, Reddy ST. PMID: 17379834; PMCID: PMC3740095.
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    166. A novel anti-atherogenic role for COX-2--potential mechanism for the cardiovascular side effects of COX-2 inhibitors. Prostaglandins Other Lipid Mediat. 2007 Aug; 84(1-2):24-33. Narasimha A, Watanabe J, Lin JA, Hama S, Langenbach R, Navab M, Fogelman AM, Reddy ST. PMID: 17643885; PMCID: PMC2701232.
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    167. Paraoxonase-2 deficiency enhances Pseudomonas aeruginosa quorum sensing in murine tracheal epithelia. Am J Physiol Lung Cell Mol Physiol. 2007 Apr; 292(4):L852-60. Stoltz DA, Ozer EA, Ng CJ, Yu JM, Reddy ST, Lusis AJ, Bourquard N, Parsek MR, Zabner J, Shih DM. PMID: 17122353.
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    168. Apolipoprotein A-I mimetic peptides and their role in atherosclerosis prevention. Nat Clin Pract Cardiovasc Med. 2006 Oct; 3(10):540-7. Navab M, Anantharamaiah GM, Reddy ST, Fogelman AM. PMID: 16990839.
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    169. Mechanisms of disease: proatherogenic HDL--an evolving field. Nat Clin Pract Endocrinol Metab. 2006 Sep; 2(9):504-11. Navab M, Anantharamaiah GM, Reddy ST, Van Lenten BJ, Ansell BJ, Fogelman AM. PMID: 16957764.
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    170. Adenovirus mediated expression of human paraoxonase 2 protects against the development of atherosclerosis in apolipoprotein E-deficient mice. Mol Genet Metab. 2006 Dec; 89(4):368-73. Ng CJ, Hama SY, Bourquard N, Navab M, Reddy ST. PMID: 16935014.
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    171. Paraoxonase-2 deficiency aggravates atherosclerosis in mice despite lower apolipoprotein-B-containing lipoproteins: anti-atherogenic role for paraoxonase-2. J Biol Chem. 2006 Oct 06; 281(40):29491-500. Ng CJ, Bourquard N, Grijalva V, Hama S, Shih DM, Navab M, Fogelman AM, Lusis AJ, Young S, Reddy ST. PMID: 16891303.
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    172. Effect of altering dietary omega-6/omega-3 fatty acid ratios on prostate cancer membrane composition, cyclooxygenase-2, and prostaglandin E2. Clin Cancer Res. 2006 Aug 01; 12(15):4662-70. Kobayashi N, Barnard RJ, Henning SM, Elashoff D, Reddy ST, Cohen P, Leung P, Hong-Gonzalez J, Freedland SJ, Said J, Gui D, Seeram NP, Popoviciu LM, Bagga D, Heber D, Glaspy JA, Aronson WJ. PMID: 16899616; PMCID: PMC3410648.
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    173. Potential clinical utility of high-density lipoprotein-mimetic peptides. Curr Opin Lipidol. 2006 Aug; 17(4):440-4. Navab M, Anantharamaiah GM, Reddy ST, Van Lenten BJ, Datta G, Garber D, Fogelman AM. PMID: 16832169.
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    174. Understanding changes in high density lipoproteins during the acute phase response. Arterioscler Thromb Vasc Biol. 2006 Aug; 26(8):1687-8. Van Lenten BJ, Reddy ST, Navab M, Fogelman AM. PMID: 16857958.
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    175. D-4F decreases brain arteriole inflammation and improves cognitive performance in LDL receptor-null mice on a Western diet. J Lipid Res. 2006 Oct; 47(10):2148-60. Buga GM, Frank JS, Mottino GA, Hendizadeh M, Hakhamian A, Tillisch JH, Reddy ST, Navab M, Anantharamaiah GM, Ignarro LJ, Fogelman AM. PMID: 16835442.
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    176. Synthetic peptides: managing lipid disorders. Curr Opin Lipidol. 2006 Jun; 17(3):233-7. Anantharamaiah G, Navab M, Reddy ST, Garber DW, Datta G, Gupta H, White CR, Handattu SP, Palgunachari MN, Chaddha M, Mishra VK, Segrest JP, Fogelman AM. PMID: 16680027.
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    177. Oral amphipathic peptides as therapeutic agents. Expert Opin Investig Drugs. 2006 Jan; 15(1):13-21. Reddy ST, Anantharamaiah GM, Navab M, Hama S, Hough G, Grijalva V, Garber DW, Datta G, Fogelman AM. PMID: 16370930.
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    178. Characterization of serum biomarkers for detection of early stage ovarian cancer. Proteomics. 2005 Nov; 5(17):4589-96. Kozak KR, Su F, Whitelegge JP, Faull K, Reddy S, Farias-Eisner R. PMID: 16237736.
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    179. Oxidized phospholipids mediate occludin expression and phosphorylation in vascular endothelial cells. Am J Physiol Heart Circ Physiol. 2006 Feb; 290(2):H674-83. DeMaio L, Rouhanizadeh M, Reddy S, Sevanian A, Hwang J, Hsiai TK. PMID: 16172163.
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    180. Oral small peptides render HDL antiinflammatory in mice and monkeys and reduce atherosclerosis in ApoE null mice. Circ Res. 2005 Sep 16; 97(6):524-32. Navab M, Anantharamaiah GM, Reddy ST, Hama S, Hough G, Frank JS, Grijalva VR, Ganesh VK, Mishra VK, Palgunachari MN, Fogelman AM. PMID: 16100046.
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    181. An oral apoJ peptide renders HDL antiinflammatory in mice and monkeys and dramatically reduces atherosclerosis in apolipoprotein E-null mice. Arterioscler Thromb Vasc Biol. 2005 Sep; 25(9):1932-7. Navab M, Anantharamaiah GM, Reddy ST, Van Lenten BJ, Wagner AC, Hama S, Hough G, Bachini E, Garber DW, Mishra VK, Palgunachari MN, Fogelman AM. PMID: 15961700.
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    182. D-4F and statins synergize to render HDL antiinflammatory in mice and monkeys and cause lesion regression in old apolipoprotein E-null mice. Arterioscler Thromb Vasc Biol. 2005 Jul; 25(7):1426-32. Navab M, Anantharamaiah GM, Hama S, Hough G, Reddy ST, Frank JS, Garber DW, Handattu S, Fogelman AM. PMID: 15845909.
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    183. Apolipoprotein A-I mimetic peptides. Arterioscler Thromb Vasc Biol. 2005 Jul; 25(7):1325-31. Navab M, Anantharamaiah GM, Reddy ST, Hama S, Hough G, Grijalva VR, Yu N, Ansell BJ, Datta G, Garber DW, Fogelman AM. PMID: 15831812.
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    184. The paraoxonase gene family and atherosclerosis. Free Radic Biol Med. 2005 Jan 15; 38(2):153-63. Ng CJ, Shih DM, Hama SY, Villa N, Navab M, Reddy ST. PMID: 15607899.
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    185. The double jeopardy of HDL. Ann Med. 2005; 37(3):173-8. Navab M, Ananthramaiah GM, Reddy ST, Van Lenten BJ, Ansell BJ, Hama S, Hough G, Bachini E, Grijalva VR, Wagner AC, Shaposhnik Z, Fogelman AM. PMID: 16019715.
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    186. Human apolipoprotein A-I and A-I mimetic peptides: potential for atherosclerosis reversal. Curr Opin Lipidol. 2004 Dec; 15(6):645-9. Navab M, Anantharamaiah GM, Reddy ST, Van Lenten BJ, Datta G, Garber D, Fogelman AM. PMID: 15529023.
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    187. Targeting c-Mpl for revival of human immunodeficiency virus type 1-induced hematopoietic inhibition when CD34+ progenitor cells are re-engrafted into a fresh stromal microenvironment in vivo. J Virol. 2004 Oct; 78(20):11385-92. Koka PS, Kitchen CM, Reddy ST. PMID: 15452260; PMCID: PMC521839.
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    188. Potential role for mitogen-activated protein kinase phosphatase-1 in the development of atherosclerotic lesions in mouse models. Arterioscler Thromb Vasc Biol. 2004 Sep; 24(9):1676-81. Reddy ST, Nguyen JT, Grijalva V, Hough G, Hama S, Navab M, Fogelman AM. PMID: 15242861.
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    189. Cytopenias in HIV infection: mechanisms and alleviation of hematopoietic inhibition. Curr HIV Res. 2004 Jul; 2(3):275-82. Koka PS, Reddy ST. PMID: 15279591.
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    190. Oral D-4F causes formation of pre-beta high-density lipoprotein and improves high-density lipoprotein-mediated cholesterol efflux and reverse cholesterol transport from macrophages in apolipoprotein E-null mice. Circulation. 2004 Jun 29; 109(25):3215-20. Navab M, Anantharamaiah GM, Reddy ST, Hama S, Hough G, Grijalva VR, Wagner AC, Frank JS, Datta G, Garber D, Fogelman AM. PMID: 15197147.
      View in: PubMed   Mentions: 133     Fields:    Translation:HumansAnimalsCells
    191. Oxidized phospholipids increase interleukin 8 (IL-8) synthesis by activation of the c-src/signal transducers and activators of transcription (STAT)3 pathway. J Biol Chem. 2004 Jul 16; 279(29):30175-81. Yeh M, Gharavi NM, Choi J, Hsieh X, Reed E, Mouillesseaux KP, Cole AL, Reddy ST, Berliner JA. PMID: 15143062.
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    192. The oxidation hypothesis of atherogenesis: the role of oxidized phospholipids and HDL. J Lipid Res. 2004 Jun; 45(6):993-1007. Navab M, Ananthramaiah GM, Reddy ST, Van Lenten BJ, Ansell BJ, Fonarow GC, Vahabzadeh K, Hama S, Hough G, Kamranpour N, Berliner JA, Lusis AJ, Fogelman AM. PMID: 15060092.
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    193. Apparent paradox of low-fat "healthy" diets increasing plasma levels of oxidized low-density lipoprotein and lipoprotein(a). Arterioscler Thromb Vasc Biol. 2004 Mar; 24(3):392-3. Navab M, Reddy ST, Van Lenten BJ, Fogelman AM. PMID: 15003971.
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    194. Inflammatory/antiinflammatory properties of high-density lipoprotein distinguish patients from control subjects better than high-density lipoprotein cholesterol levels and are favorably affected by simvastatin treatment. Circulation. 2003 Dec 02; 108(22):2751-6. Ansell BJ, Navab M, Hama S, Kamranpour N, Fonarow G, Hough G, Rahmani S, Mottahedeh R, Dave R, Reddy ST, Fogelman AM. PMID: 14638544.
      View in: PubMed   Mentions: 223     Fields:    Translation:HumansCellsCTClinical Trials
    195. Identification of biomarkers for ovarian cancer using strong anion-exchange ProteinChips: potential use in diagnosis and prognosis. Proc Natl Acad Sci U S A. 2003 Oct 14; 100(21):12343-8. Kozak KR, Amneus MW, Pusey SM, Su F, Luong MN, Luong SA, Reddy ST, Farias-Eisner R. PMID: 14523236; PMCID: PMC218760.
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    196. Human apolipoprotein AI mimetic peptides for the treatment of atherosclerosis. Curr Opin Investig Drugs. 2003 Sep; 4(9):1100-4. Navab M, Anantharamaiah GM, Reddy ST, Van Lenten BJ, Hough G, Wagner A, Nakamura K, Garber DW, Datta G, Segrest JP, Hama S, Fogelman AM. PMID: 14582455.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansAnimals
    197. Differential effects of prostaglandin derived from omega-6 and omega-3 polyunsaturated fatty acids on COX-2 expression and IL-6 secretion. Proc Natl Acad Sci U S A. 2003 Feb 18; 100(4):1751-6. Bagga D, Wang L, Farias-Eisner R, Glaspy JA, Reddy ST. PMID: 12578976; PMCID: PMC149905.
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    198. 17-epiestriol, an estrogen metabolite, is more potent than estradiol in inhibiting vascular cell adhesion molecule 1 (VCAM-1) mRNA expression. J Biol Chem. 2003 Apr 04; 278(14):11746-52. Mukherjee TK, Nathan L, Dinh H, Reddy ST, Chaudhuri G. PMID: 12547825.
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    199. Prostaglandin H synthase 2 variant (Val511Ala) in African Americans may reduce the risk for colorectal neoplasia. Cancer Epidemiol Biomarkers Prev. 2002 Nov; 11(11):1305-15. Lin HJ, Lakkides KM, Keku TO, Reddy ST, Louie AD, Kau IH, Zhou H, Gim JS, Ma HL, Matthies CF, Dai A, Huang HF, Materi AM, Lin JH, Frankl HD, Lee ER, Hardy SI, Herschman HR, Henderson BE, Kolonel LN, Le Marchand L, Garavito RM, Sandler RS, Haile RW, Smith WL. PMID: 12433707.
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    200. ATP-binding cassette transporter 1 participates in LDL oxidation by artery wall cells. Arterioscler Thromb Vasc Biol. 2002 Nov 01; 22(11):1877-83. Reddy ST, Hama S, Ng C, Grijalva V, Navab M, Fogelman AM. PMID: 12426219.
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    201. Diesel exhaust particle extracts and associated polycyclic aromatic hydrocarbons inhibit Cox-2-dependent prostaglandin synthesis in murine macrophages and fibroblasts. J Biol Chem. 2002 Oct 18; 277(42):39259-65. Rudra-Ganguly N, Reddy ST, Korge P, Herschman HR. PMID: 12163478.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCellsPHPublic Health
    202. Urokinase plasminogen activator receptor: Prognostic biomarker for endometrial cancer. Proc Natl Acad Sci U S A. 2002 Aug 06; 99(16):10647-52. Memarzadeh S, Kozak KR, Chang L, Natarajan S, Shintaku P, Reddy ST, Farias-Eisner R, Memarzedeh S. PMID: 12130664; PMCID: PMC125001.
      View in: PubMed   Mentions: 24     Fields:    Translation:Humans
    203. Identification of genes induced by oxidized phospholipids in human aortic endothelial cells. Vascul Pharmacol. 2002 Apr; 38(4):211-8. Reddy ST, Grijalva V, Ng C, Hassan K, Hama S, Mottahedeh R, Wadleigh DJ, Navab M, Fogelman AM. PMID: 12449017.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansCells
    204. Human paraoxonase-3 is an HDL-associated enzyme with biological activity similar to paraoxonase-1 protein but is not regulated by oxidized lipids. Arterioscler Thromb Vasc Biol. 2001 Apr; 21(4):542-7. Reddy ST, Wadleigh DJ, Grijalva V, Ng C, Hama S, Gangopadhyay A, Shih DM, Lusis AJ, Navab M, Fogelman AM. PMID: 11304470.
      View in: PubMed   Mentions: 106     Fields:    Translation:HumansAnimalsCells
    205. Mitogen-activated protein kinase phosphatase 1 activity is necessary for oxidized phospholipids to induce monocyte chemotactic activity in human aortic endothelial cells. J Biol Chem. 2001 May 18; 276(20):17030-5. Reddy S, Hama S, Grijalva V, Hassan K, Mottahedeh R, Hough G, Wadleigh DJ, Navab M, Fogelman AM. PMID: 11278958.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansCells
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