Mansoureh Eghbali

Title(s)Professor, Anesthesiology
SchoolMedicine
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    Role of Chromosome Y gene, Uty, in protecting against Pulmonary Hypertension
    NIH R01HL159865Jul 20, 2021 - Jun 30, 2025
    Role: Principal Investigator
    Role of miR125 in pulmonary hypertension secondary to interstitial lung disease
    NIH R01HL147586Dec 1, 2019 - Nov 30, 2023
    Role: Principal Investigator
    Role of miR193 in oxidized lipid induced pulmonary hypertension
    NIH R01HL129051Aug 15, 2016 - Jun 30, 2021
    Role: Principal Investigator
    Epigenetic regulation of myocardial ischemia/reperfusion injury by X chromosome
    NIH R01HL131182Apr 15, 2016 - Mar 31, 2021
    Role: Principal Investigator
    Sex differences in myocardial ischemia/reperfusion injury
    NIH R56HL119886Jul 24, 2014 - Dec 31, 2015
    Role: Co-Principal Investigator
    Cardiac KCNE2 (MIRP1) Regulation by Estrogen and Cardiac Stress
    NIH R01HL089876Jul 14, 2008 - Apr 30, 2014
    Role: Principal Investigator

    Collapse Bibliographic 
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Transcriptome analyses reveal common immune system dysregulation in PAH patients and Kcnk3-deficient rats. Pulm Circ. 2024 Oct; 14(4):e12434. Ruffenach G, Le Ribeuz H, Dutheil M, El Jekmek K, Dumont F, Willer AS, Humbert M, Capuano V, Medzikovic L, Eghbali M, Montani D, Antigny F. PMID: 39444497; PMCID: PMC11497494.
      View in: PubMed   Mentions:
    2. Integrative Multiomics in the Lung Reveals a Protective Role of Asporin in Pulmonary Arterial Hypertension. Circulation. 2024 Oct 15; 150(16):1268-1287. Hong J, Medzikovic L, Sun W, Wong B, Ruffenach G, Rhodes CJ, Brownstein A, Liang LL, Aryan L, Li M, Vadgama A, Kurt Z, Schwantes-An TH, Mickler EA, Gräf S, Eyries M, Lutz KA, Pauciulo MW, Trembath RC, Perros F, Montani D, Morrell NW, Soubrier F, Wilkins MR, Nichols WC, Aldred MA, Desai AA, Trégouët DA, Umar S, Saggar R, Channick R, Tuder RM, Geraci MW, Stearman RS, Yang X, Eghbali M. PMID: 39167456; PMCID: PMC11473243.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    3. Dissecting the lung transcriptome of pulmonary fibrosis-associated pulmonary hypertension. Am J Physiol Lung Cell Mol Physiol. 2024 Oct 01; 327(4):L520-L534. Brownstein AJ, Mura M, Ruffenach G, Channick RN, Saggar R, Kim A, Umar S, Eghbali M, Yang X, Hong J. PMID: 39137526; PMCID: PMC11482468.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    4. Guidelines for assessing maternal cardiovascular physiology during pregnancy and postpartum. Am J Physiol Heart Circ Physiol. 2024 07 01; 327(1):H191-H220. Collins HE, Alexander BT, Care AS, Davenport MH, Davidge ST, Eghbali M, Giussani DA, Hoes MF, Julian CG, LaVoie HA, Olfert IM, Ozanne SE, Bytautiene Prewit E, Warrington JP, Zhang L, Goulopoulou S. PMID: 38758127; PMCID: PMC11380979.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimals
    5. Effects of particle size reduction of meadow hay on feed intake, performance, and apparent total tract nutrient digestibility in dairy cows. Arch Anim Nutr. 2023 Dec; 77(6):452-467. Bauer K, Eghbali M, Hartinger T, Haselmann A, Fuerst-Waltl B, Zollitsch W, Zebeli Q, Knaus W. PMID: 38012072.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimals
    6. Functions of RNA-Binding Proteins in Cardiovascular Disease. Cells. 2023 12 08; 12(24). Ruffenach G, Medzikovic L, Sun W, Hong J, Eghbali M. PMID: 38132114; PMCID: PMC10742114.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    7. Amnion responses to intrauterine inflammation and effects of inhibition of TNF signaling in preterm Rhesus macaque. iScience. 2023 Nov 17; 26(11):108118. Presicce P, Cappelletti M, Morselli M, Ma F, Senthamaraikannan P, Protti G, Nadel BB, Aryan L, Eghbali M, Salwinski L, Pithia N, De Franco E, Miller LA, Pellegrini M, Jobe AH, Chougnet CA, Kallapur SG. PMID: 37953944; PMCID: PMC10637919.
      View in: PubMed   Mentions: 1  
    8. 17 β-Estradiol Impedes Aortic Root Dilation and Rupture in Male Marfan Mice. Int J Mol Sci. 2023 Sep 01; 24(17). Saddic L, Escopete S, Zilberberg L, Kalsow S, Gupta D, Eghbali M, Parker S. PMID: 37686377; PMCID: PMC10487461.
      View in: PubMed   Mentions: 1     Fields:    Translation:Animals
    9. Sex Differences in Therapies against Myocardial Ischemia-Reperfusion Injury: From Basic Science to Clinical Perspectives. Cells. 2023 08 16; 12(16). Medzikovic L, Azem T, Sun W, Rejali P, Esdin L, Rahman S, Dehghanitafti A, Aryan L, Eghbali M. PMID: 37626887; PMCID: PMC10453147.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    10. Myocardial fibrosis and calcification are attenuated by microRNA-129-5p targeting Asporin and Sox9 in cardiac fibroblasts. JCI Insight. 2023 05 08; 8(9). Medzikovic L, Aryan L, Ruffenach G, Li M, Savalli N, Sun W, Sarji S, Hong J, Sharma S, Olcese R, Fishbein G, Eghbali M. PMID: 37154157; PMCID: PMC10243800.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansAnimalsCells
    11. Tm4sf1-marked Endothelial Subpopulation Is Dysregulated in Pulmonary Arterial Hypertension. Am J Respir Cell Mol Biol. 2023 04; 68(4):381-394. Hong J, Wong B, Huynh C, Tang B, Ruffenach G, Li M, Umar S, Yang X, Eghbali M. PMID: 36252184; PMCID: PMC10112423.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimalsCells
    12. Integrative Multiomics to Dissect the Lung Transcriptional Landscape of Pulmonary Arterial Hypertension. bioRxiv. 2023 Jan 16. Hong J, Wong B, Rhodes CJ, Kurt Z, Schwantes-An TH, Mickler EA, Gräf S, Eyries M, Lutz KA, Pauciulo MW, Trembath RC, Montani D, Morrell NW, Wilkins MR, Nichols WC, Trégouët DA, Aldred MA, Desai AA, Tuder RM, Geraci MW, Eghbali M, Stearman RS, Yang X. PMID: 36712057; PMCID: PMC9882207.
      View in: PubMed   Mentions: 2  
    13. Intralipid® improves left ventricular function in rats with lipopolysaccharide-induced endotoxaemia by a Src-STAT3-mediated mechanism. Br J Anaesth. 2023 02; 130(2):e183-e187. Banerjee S, Zargari M, Medzikovic L, Russino H, Mikhael M, Koons N, Grogan T, Rahman S, Eghbali M, Umar S. PMID: 36462942; PMCID: PMC10170391.
      View in: PubMed   Mentions:    Fields:    Translation:Animals
    14. HNRNPA2B1: RNA-Binding Protein That Orchestrates Smooth Muscle Cell Phenotype in Pulmonary Arterial Hypertension. Circulation. 2022 10 18; 146(16):1243-1258. Ruffenach G, Medzikovic L, Aryan L, Li M, Eghbali M. PMID: 35993245; PMCID: PMC9588778.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansAnimalsCells
    15. Intralipid fails to rescue bupivacaine-induced cardiotoxicity in late-pregnant rats. Front Med (Lausanne). 2022; 9:899036. Sherman C, Koons N, Zargari M, Cha C, Hirsch J, Hong R, Eghbali M, Umar S. PMID: 36035396; PMCID: PMC9411664.
      View in: PubMed   Mentions:
    16. Y-Chromosome Gene, Uty, Protects Against Pulmonary Hypertension by Reducing Proinflammatory Chemokines. Am J Respir Crit Care Med. 2022 07 15; 206(2):186-196. Cunningham CM, Li M, Ruffenach G, Doshi M, Aryan L, Hong J, Park J, Hrncir H, Medzikovic L, Umar S, Arnold AP, Eghbali M. PMID: 35504005; PMCID: PMC9887415.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansAnimalsCells
    17. Role of miRNA-1 and miRNA-21 in Acute Myocardial Ischemia-Reperfusion Injury and Their Potential as Therapeutic Strategy. Int J Mol Sci. 2022 Jan 28; 23(3). Jayawardena E, Medzikovic L, Ruffenach G, Eghbali M. PMID: 35163436; PMCID: PMC8836257.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansAnimals
    18. Radiosensitizing Pancreatic Cancer via Effective Autophagy Inhibition. Mol Cancer Ther. 2022 01; 21(1):79-88. Yazal T, Bailleul J, Ruan Y, Sung D, Chu FI, Palomera D, Dao A, Sehgal A, Gurunathan V, Aryan L, Eghbali M, Vlashi E. PMID: 34725193.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimals
    19. A novel miRNA biomarker panel associated with mortality in pediatric patients with ARDS. Respir Res. 2021 Jun 04; 22(1):169. Lee LK, Eghbali M, Sapru A. PMID: 34088312; PMCID: PMC8177032.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    20. Single-Cell Study of Two Rat Models of Pulmonary Arterial Hypertension Reveals Connections to Human Pathobiology and Drug Repositioning. Am J Respir Crit Care Med. 2021 04 15; 203(8):1006-1022. Hong J, Arneson D, Umar S, Ruffenach G, Cunningham CM, Ahn IS, Diamante G, Bhetraratana M, Park JF, Said E, Huynh C, Le T, Medzikovic L, Humbert M, Soubrier F, Montani D, Girerd B, Trégouët DA, Channick R, Saggar R, Eghbali M, Yang X. PMID: 33021809; PMCID: PMC8048757.
      View in: PubMed   Mentions: 31     Fields:    Translation:HumansAnimalsCells
    21. Editorial: Oxidative Stress in Myocardial and Neural Remodeling. Front Physiol. 2021; 12:606484. Nguyen TP, Frautschy SA, Eghbali M. PMID: 33613307; PMCID: PMC7893088.
      View in: PubMed   Mentions:
    22. Pulmonary hypertension secondary to pulmonary fibrosis: clinical data, histopathology and molecular insights. Respir Res. 2020 Nov 18; 21(1):303. Ruffenach G, Hong J, Vaillancourt M, Medzikovic L, Eghbali M. PMID: 33208169; PMCID: PMC7677848.
      View in: PubMed   Mentions: 31     Fields:    Translation:HumansAnimals
    23. The Role of MicroRNAs in Acute Respiratory Distress Syndrome and Sepsis, From Targets to Therapies: A Narrative Review. Anesth Analg. 2020 11; 131(5):1471-1484. Lee LK, Medzikovic L, Eghbali M, Eltzschig HK, Yuan X. PMID: 33079870; PMCID: PMC8532045.
      View in: PubMed   Mentions: 22     Fields:    Translation:HumansAnimals
    24. Sex differences underlying preexisting cardiovascular disease and cardiovascular injury in COVID-19. J Mol Cell Cardiol. 2020 11; 148:25-33. Medzikovic L, Cunningham CM, Li M, Amjedi M, Hong J, Ruffenach G, Eghbali M. PMID: 32835666; PMCID: PMC7442559.
      View in: PubMed   Mentions: 20     Fields:    Translation:Humans
    25. Oral 15-Hydroxyeicosatetraenoic Acid Induces Pulmonary Hypertension in Mice by Triggering T Cell-Dependent Endothelial Cell Apoptosis. Hypertension. 2020 09; 76(3):985-996. Ruffenach G, O'Connor E, Vaillancourt M, Hong J, Cao N, Sarji S, Moazeni S, Papesh J, Grijalva V, Cunningham CM, Shu L, Chattopadhyay A, Tiwari S, Mercier O, Perros F, Umar S, Yang X, Gomes AV, Fogelman AM, Reddy ST, Eghbali M. PMID: 32713273; PMCID: PMC8008496.
      View in: PubMed   Mentions: 11     Fields:    Translation:AnimalsCells
    26. The Role of Estrogen Receptors in Cardiovascular Disease. Int J Mol Sci. 2020 Jun 17; 21(12). Aryan L, Younessi D, Zargari M, Banerjee S, Agopian J, Rahman S, Borna R, Ruffenach G, Umar S, Eghbali M. PMID: 32560398; PMCID: PMC7352426.
      View in: PubMed   Mentions: 57     Fields:    Translation:HumansAnimalsCells
    27. Pregnancy-associated cardiac dysfunction and the regulatory role of microRNAs. Biol Sex Differ. 2020 04 06; 11(1):14. Aryan L, Medzikovic L, Umar S, Eghbali M. PMID: 32252821; PMCID: PMC7137306.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansAnimals
    28. Involvement of Low-Density Lipoprotein Receptor in the Pathogenesis of Pulmonary Hypertension. J Am Heart Assoc. 2020 01 21; 9(2):e012063. Umar S, Ruffenach G, Moazeni S, Vaillancourt M, Hong J, Cunningham C, Cao N, Navab S, Sarji S, Li M, Lee L, Fishbein G, Ardehali A, Navab M, Reddy ST, Eghbali M. PMID: 31914876; PMCID: PMC7033825.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansAnimalsCells
    29. Oxidative Stress and Its Implications in the Right Ventricular Remodeling Secondary to Pulmonary Hypertension. Front Physiol. 2019; 10:1233. Mikhael M, Makar C, Wissa A, Le T, Eghbali M, Umar S. PMID: 31607955; PMCID: PMC6769067.
      View in: PubMed   Mentions: 12  
    30. Radiation mitigation of the intestinal acute radiation injury in mice by 1-[(4-nitrophenyl)sulfonyl]-4-phenylpiperazine. Stem Cells Transl Med. 2020 01; 9(1):106-119. Duhachek-Muggy S, Bhat K, Medina P, Cheng F, He L, Alli C, Saki M, Muthukrishnan SD, Ruffenach G, Eghbali M, Vlashi E, Pajonk F. PMID: 31464098; PMCID: PMC6954722.
      View in: PubMed   Mentions: 8     Fields:    Translation:AnimalsPHPublic Health
    31. Histological hallmarks and role of Slug/PIP axis in pulmonary hypertension secondary to pulmonary fibrosis. EMBO Mol Med. 2019 09; 11(9):e10061. Ruffenach G, Umar S, Vaillancourt M, Hong J, Cao N, Sarji S, Moazeni S, Cunningham CM, Ardehali A, Reddy ST, Saggar R, Fishbein G, Eghbali M. PMID: 31468711; PMCID: PMC6728601.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansAnimalsCells
    32. Connecting sex differences, estrogen signaling, and microRNAs in cardiac fibrosis. J Mol Med (Berl). 2019 10; 97(10):1385-1398. Medzikovic L, Aryan L, Eghbali M. PMID: 31448389.
      View in: PubMed   Mentions: 22     Fields:    Translation:HumansAnimalsCells
    33. In Reply. Anesthesiology. 2019 03; 130(3):519-521. Umar S, Eghbali M. PMID: 30762648.
      View in: PubMed   Mentions:    Fields:    
    34. Paraoxonase 2 protects against acute myocardial ischemia-reperfusion injury by modulating mitochondrial function and oxidative stress via the PI3K/Akt/GSK-3β RISK pathway. J Mol Cell Cardiol. 2019 04; 129:154-164. Sulaiman D, Li J, Devarajan A, Cunningham CM, Li M, Fishbein GA, Fogelman AM, Eghbali M, Reddy ST. PMID: 30802459.
      View in: PubMed   Mentions: 31     Fields:    Translation:HumansAnimalsCells
    35. Estrogen rescues heart failure through estrogen receptor Beta activation. Biol Sex Differ. 2018 10 30; 9(1):48. Iorga A, Umar S, Ruffenach G, Aryan L, Li J, Sharma S, Motayagheni N, Nadadur RD, Bopassa JC, Eghbali M. PMID: 30376877; PMCID: PMC6208048.
      View in: PubMed   Mentions: 29     Fields:    Translation:AnimalsCells
    36. Progression of myocardial ischemia leads to unique changes in immediate-early gene expression in the spinal cord dorsal horn. Am J Physiol Heart Circ Physiol. 2018 12 01; 315(6):H1592-H1601. Saddic LA, Howard-Quijano K, Kipke J, Kubo Y, Dale EA, Hoover D, Shivkumar K, Eghbali M, Mahajan A. PMID: 30216122; PMCID: PMC6336975.
      View in: PubMed   Mentions: 12     Fields:    Translation:AnimalsCells
    37. Free Fatty Acid Receptor G-protein-coupled Receptor 40 Mediates Lipid Emulsion-induced Cardioprotection. Anesthesiology. 2018 07; 129(1):154-162. Umar S, Li J, Hannabass K, Vaillancourt M, Cunningham CM, Moazeni S, Mahajan A, Eghbali M. PMID: 29620570; PMCID: PMC6084795.
      View in: PubMed   Mentions: 7     Fields:    Translation:AnimalsCells
    38. The Y Chromosome Plays a Protective Role in Experimental Hypoxic Pulmonary Hypertension. Am J Respir Crit Care Med. 2018 04 01; 197(7):952-955. Umar S, Cunningham CM, Itoh Y, Moazeni S, Vaillancourt M, Sarji S, Centala A, Arnold AP, Eghbali M. PMID: 28934553; PMCID: PMC6020406.
      View in: PubMed   Mentions: 38     Fields:    Translation:AnimalsCells
    39. An Introduction to Epigenetics in Cardiovascular Development, Disease, and Sexualization. Adv Exp Med Biol. 2018; 1065:31-47. Cunningham CM, Eghbali M. PMID: 30051375.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimalsCells
    40. Autonomic nervous system involvement in pulmonary arterial hypertension. Respir Res. 2017 12 04; 18(1):201. Vaillancourt M, Chia P, Sarji S, Nguyen J, Hoftman N, Ruffenach G, Eghbali M, Mahajan A, Umar S. PMID: 29202826; PMCID: PMC5715548.
      View in: PubMed   Mentions: 49     Fields:    Translation:HumansAnimals
    41. The protective role of estrogen and estrogen receptors in cardiovascular disease and the controversial use of estrogen therapy. Biol Sex Differ. 2017 10 24; 8(1):33. Iorga A, Cunningham CM, Moazeni S, Ruffenach G, Umar S, Eghbali M. PMID: 29065927; PMCID: PMC5655818.
      View in: PubMed   Mentions: 298     Fields:    Translation:HumansAnimals
    42. Advances in treatment of pulmonary arterial hypertension: patent review. Expert Opin Ther Pat. 2017 Aug; 27(8):907-918. Vaidya B, Pangallo M, Ruffenach G, Cunningham CM, Perron JC, Kolluru S, Eghbali M, Gupta V. PMID: 28355094.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimals
    43. Severe pulmonary hypertension in aging female apolipoprotein E-deficient mice is rescued by estrogen replacement therapy. Biol Sex Differ. 2017; 8:9. Umar S, Partow-Navid R, Ruffenach G, Iorga A, Moazeni S, Eghbali M. PMID: 28344760; PMCID: PMC5360087.
      View in: PubMed   Mentions: 7     Fields:    Translation:Animals
    44. Sex Hormones and Sex Chromosomes Cause Sex Differences in the Development of Cardiovascular Diseases. Arterioscler Thromb Vasc Biol. 2017 05; 37(5):746-756. Arnold AP, Cassis LA, Eghbali M, Reue K, Sandberg K. PMID: 28279969; PMCID: PMC5437981.
      View in: PubMed   Mentions: 139     Fields:    Translation:HumansAnimalsCells
    45. Intralipid protects the heart in late pregnancy against ischemia/reperfusion injury via Caveolin2/STAT3/GSK-3β pathway. J Mol Cell Cardiol. 2017 01; 102:108-116. Li J, Ruffenach G, Kararigas G, Cunningham CM, Motayagheni N, Barakai N, Umar S, Regitz-Zagrosek V, Eghbali M. PMID: 27847332; PMCID: PMC5831539.
      View in: PubMed   Mentions: 17     Fields:    Translation:AnimalsCells
    46. Role of oxidized lipids in pulmonary arterial hypertension. Pulm Circ. 2016 Sep; 6(3):261-73. Sharma S, Ruffenach G, Umar S, Motayagheni N, Reddy ST, Eghbali M. PMID: 27683603; PMCID: PMC5019079.
      View in: PubMed   Mentions: 22  
    47. Novel biomarkers for pulmonary arterial hypertension. Respir Res. 2016 07 20; 17(1):88. Anwar A, Ruffenach G, Mahajan A, Eghbali M, Umar S. PMID: 27439993; PMCID: PMC4955255.
      View in: PubMed   Mentions: 25     Fields:    Translation:HumansAnimals
    48. The importance of having two X chromosomes. Philos Trans R Soc Lond B Biol Sci. 2016 Feb 19; 371(1688):20150113. Arnold AP, Reue K, Eghbali M, Vilain E, Chen X, Ghahramani N, Itoh Y, Li J, Link JC, Ngun T, Williams-Burris SM. PMID: 26833834; PMCID: PMC4785899.
      View in: PubMed   Mentions: 53     Fields:    Translation:AnimalsCells
    49. Rescue of Pressure Overload-Induced Heart Failure by Estrogen Therapy. J Am Heart Assoc. 2016 Jan 22; 5(1). Iorga A, Li J, Sharma S, Umar S, Bopassa JC, Nadadur RD, Centala A, Ren S, Saito T, Toro L, Wang Y, Stefani E, Eghbali M. PMID: 26802104; PMCID: PMC4859364.
      View in: PubMed   Mentions: 36     Fields:    Translation:AnimalsCells
    50. Proinflammatory high-density lipoprotein results from oxidized lipid mediators in the pathogenesis of both idiopathic and associated types of pulmonary arterial hypertension. Pulm Circ. 2015 Dec; 5(4):640-8. Ross DJ, Hough G, Hama S, Aboulhosn J, Belperio JA, Saggar R, Van Lenten BJ, Ardehali A, Eghbali M, Reddy S, Fogelman AM, Navab M. PMID: 26697171; PMCID: PMC4671738.
      View in: PubMed   Mentions: 29  
    51. Role of miR206 in genistein-induced rescue of pulmonary hypertension in monocrotaline model. J Appl Physiol (1985). 2015 Dec 15; 119(12):1374-82. Sharma S, Umar S, Centala A, Eghbali M. PMID: 26472874; PMCID: PMC4683348.
      View in: PubMed   Mentions: 7     Fields:    Translation:Animals
    52. Involvement of Opioid Receptors in the Lipid Rescue of Bupivacaine-Induced Cardiotoxicity. Anesth Analg. 2015 Aug; 121(2):340-7. Partownavid P, Sharma S, Li J, Umar S, Rahman S, Eghbali M. PMID: 25993392.
      View in: PubMed   Mentions: 8     Fields:    Translation:AnimalsCells
    53. Apolipoprotein A-I mimetic peptide 4F rescues pulmonary hypertension by inducing microRNA-193-3p. Circulation. 2014 Aug 26; 130(9):776-85. Sharma S, Umar S, Potus F, Iorga A, Wong G, Meriwether D, Breuils-Bonnet S, Mai D, Navab K, Ross D, Navab M, Provencher S, Fogelman AM, Bonnet S, Reddy ST, Eghbali M. PMID: 24963038; PMCID: PMC4194270.
      View in: PubMed   Mentions: 49     Fields:    Translation:HumansAnimalsCells
    54. The number of X chromosomes influences protection from cardiac ischaemia/reperfusion injury in mice: one X is better than two. Cardiovasc Res. 2014 Jun 01; 102(3):375-84. Li J, Chen X, McClusky R, Ruiz-Sundstrom M, Itoh Y, Umar S, Arnold AP, Eghbali M. PMID: 24654234; PMCID: PMC4030514.
      View in: PubMed   Mentions: 53     Fields:    Translation:AnimalsCells
    55. Influence of sex differences on microRNA gene regulation in disease. Biol Sex Differ. 2014 Feb 01; 5(1):3. Sharma S, Eghbali M. PMID: 24484532; PMCID: PMC3912347.
      View in: PubMed   Mentions: 83     Fields:    
    56. Inotropic effect of lipid emulsion: a new perspective*. Crit Care Med. 2013 Aug; 41(8):2060-1. Li J, Rahman S, Eghbali M. PMID: 23863251.
      View in: PubMed   Mentions:    Fields:    Translation:Animals
    57. In reply. Anesthesiology. 2013 May; 118(5):1238-40. Li J, Bopassa JC, Rahman S, Eghbali M. PMID: 23612141.
      View in: PubMed   Mentions:    Fields:    Translation:Animals
    58. Pregnancy is associated with decreased cardiac proteasome activity and oxidative stress in mice. PLoS One. 2012; 7(11):e48601. Iorga A, Dewey S, Partow-Navid R, Gomes AV, Eghbali M. PMID: 23166589; PMCID: PMC3499532.
      View in: PubMed   Mentions: 14     Fields:    Translation:AnimalsCells
    59. Intralipid, a clinically safe compound, protects the heart against ischemia-reperfusion injury more efficiently than cyclosporine-A. Anesthesiology. 2012 Oct; 117(4):836-46. Li J, Iorga A, Sharma S, Youn JY, Partow-Navid R, Umar S, Cai H, Rahman S, Eghbali M. PMID: 22814384; PMCID: PMC3769111.
      View in: PubMed   Mentions: 37     Fields:    Translation:AnimalsCells
    60. Cardiac structural and hemodynamic changes associated with physiological heart hypertrophy of pregnancy are reversed postpartum. J Appl Physiol (1985). 2012 Oct 15; 113(8):1253-9. Umar S, Nadadur R, Iorga A, Amjedi M, Matori H, Eghbali M. PMID: 22923507; PMCID: PMC3472485.
      View in: PubMed   Mentions: 32     Fields:    Translation:AnimalsCells
    61. Fatty-acid oxidation and calcium homeostasis are involved in the rescue of bupivacaine-induced cardiotoxicity by lipid emulsion in rats. Crit Care Med. 2012 Aug; 40(8):2431-7. Partownavid P, Umar S, Li J, Rahman S, Eghbali M. PMID: 22647409; PMCID: PMC3401289.
      View in: PubMed   Mentions: 38     Fields:    Translation:AnimalsCells
    62. New frontiers in heart hypertrophy during pregnancy. Am J Cardiovasc Dis. 2012; 2(3):192-207. Li J, Umar S, Amjedi M, Iorga A, Sharma S, Nadadur RD, Regitz-Zagrosek V, Eghbali M. PMID: 22937489; PMCID: PMC3427979.
      View in: PubMed   Mentions: 36  
    63. Genistein, a soy phytoestrogen, reverses severe pulmonary hypertension and prevents right heart failure in rats. Hypertension. 2012 Aug; 60(2):425-30. Matori H, Umar S, Nadadur RD, Sharma S, Partow-Navid R, Afkhami M, Amjedi M, Eghbali M. PMID: 22753213; PMCID: PMC4252152.
      View in: PubMed   Mentions: 37     Fields:    Translation:HumansAnimalsCells
    64. Cardiac vulnerability to ischemia/reperfusion injury drastically increases in late pregnancy. Basic Res Cardiol. 2012 Jul; 107(4):271. Li J, Umar S, Iorga A, Youn JY, Wang Y, Regitz-Zagrosek V, Cai H, Eghbali M. PMID: 22648276; PMCID: PMC3769136.
      View in: PubMed   Mentions: 16     Fields:    Translation:AnimalsCells
    65. Reverse right ventricular structural and extracellular matrix remodeling by estrogen in severe pulmonary hypertension. J Appl Physiol (1985). 2012 Jul; 113(1):149-58. Nadadur RD, Umar S, Wong G, Eghbali M, Iorga A, Matori H, Partow-Navid R, Eghbali M. PMID: 22628376; PMCID: PMC3404831.
      View in: PubMed   Mentions: 36     Fields:    Translation:AnimalsCells
    66. Estrogen paradox in pulmonary hypertension: current controversies and future perspectives. Am J Respir Crit Care Med. 2012 Jul 15; 186(2):125-31. Umar S, Rabinovitch M, Eghbali M. PMID: 22561960; PMCID: PMC3406082.
      View in: PubMed   Mentions: 37     Fields:    Translation:HumansAnimals
    67. Spontaneous ventricular fibrillation in right ventricular failure secondary to chronic pulmonary hypertension. Circ Arrhythm Electrophysiol. 2012 Feb; 5(1):181-90. Umar S, Lee JH, de Lange E, Iorga A, Partow-Navid R, Bapat A, van der Laarse A, Saggar R, Saggar R, Ypey DL, Karagueuzian HS, Eghbali M. PMID: 22199010; PMCID: PMC3319685.
      View in: PubMed   Mentions: 34     Fields:    Translation:Animals
    68. Phosphorylation of GSK-3β mediates intralipid-induced cardioprotection against ischemia/reperfusion injury. Anesthesiology. 2011 Aug; 115(2):242-53. Rahman S, Li J, Bopassa JC, Umar S, Iorga A, Partownavid P, Eghbali M. PMID: 21691195; PMCID: PMC3322241.
      View in: PubMed   Mentions: 62     Fields:    Translation:AnimalsCells
    69. Intralipid prevents and rescues fatal pulmonary arterial hypertension and right ventricular failure in rats. Hypertension. 2011 Sep; 58(3):512-8. Umar S, Nadadur RD, Li J, Maltese F, Partownavid P, van der Laarse A, Eghbali M. PMID: 21747043; PMCID: PMC3339261.
      View in: PubMed   Mentions: 11     Fields:    Translation:Animals
    70. Estrogen rescues preexisting severe pulmonary hypertension in rats. Am J Respir Crit Care Med. 2011 Sep 15; 184(6):715-23. Umar S, Iorga A, Matori H, Nadadur RD, Li J, Maltese F, van der Laarse A, Eghbali M. PMID: 21700911; PMCID: PMC3208600.
      View in: PubMed   Mentions: 79     Fields:    Translation:Animals
    71. Quantitative determination of spatial protein-protein correlations in fluorescence confocal microscopy. Biophys J. 2010 Feb 03; 98(3):493-504. Wu Y, Eghbali M, Ou J, Lu R, Toro L, Stefani E. PMID: 20141764; PMCID: PMC2814199.
      View in: PubMed   Mentions: 34     Fields:    Translation:HumansAnimalsCells
    72. A novel estrogen receptor GPER inhibits mitochondria permeability transition pore opening and protects the heart against ischemia-reperfusion injury. Am J Physiol Heart Circ Physiol. 2010 Jan; 298(1):H16-23. Bopassa JC, Eghbali M, Toro L, Stefani E. PMID: 19880667; PMCID: PMC2806134.
      View in: PubMed   Mentions: 104     Fields:    Translation:AnimalsCells
    73. Estrogen contributes to gender differences in mouse ventricular repolarization. Circ Res. 2009 Aug 14; 105(4):343-52. Saito T, Ciobotaru A, Bopassa JC, Toro L, Stefani E, Eghbali M. PMID: 19608983; PMCID: PMC2921935.
      View in: PubMed   Mentions: 47     Fields:    Translation:Animals
    74. In vivo imaging, tracking, and targeting of cancer stem cells. J Natl Cancer Inst. 2009 Mar 04; 101(5):350-9. Vlashi E, Kim K, Lagadec C, Donna LD, McDonald JT, Eghbali M, Sayre JW, Stefani E, McBride W, Pajonk F. PMID: 19244169; PMCID: PMC2727141.
      View in: PubMed   Mentions: 129     Fields:    Translation:HumansAnimalsCells
    75. Changes in global gene expression in rat myometrium in transition from late pregnancy to parturition. Physiol Genomics. 2009 Jan 08; 36(2):89-97. Helguera G, Eghbali M, Sforza D, Minosyan TY, Toro L, Stefani E. PMID: 19001510; PMCID: PMC2636924.
      View in: PubMed   Mentions: 9     Fields:    Translation:Animals
    76. Contrasting proteome biology and functional heterogeneity of the 20 S proteasome complexes in mammalian tissues. Mol Cell Proteomics. 2009 Feb; 8(2):302-15. Gomes AV, Young GW, Wang Y, Zong C, Eghbali M, Drews O, Lu H, Stefani E, Ping P. PMID: 18931337; PMCID: PMC2634581.
      View in: PubMed   Mentions: 50     Fields:    Translation:AnimalsCells
    77. c-Src tyrosine kinase, a critical component for 5-HT2A receptor-mediated contraction in rat aorta. J Physiol. 2008 Aug 15; 586(16):3855-69. Lu R, Alioua A, Kumar Y, Kundu P, Eghbali M, Weisstaub NV, Gingrich JA, Stefani E, Toro L. PMID: 18599541; PMCID: PMC2538937.
      View in: PubMed   Mentions: 19     Fields:    Translation:AnimalsCells
    78. Identification of a functional interaction between Kv4.3 channels and c-Src tyrosine kinase. Biochim Biophys Acta. 2008 Oct; 1783(10):1884-92. Gomes P, Saito T, Del Corsso C, Alioua A, Eghbali M, Toro L, Stefani E. PMID: 18620005; PMCID: PMC2617707.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
    79. Hormonal regulation of cardiac KCNE2 gene expression. Mol Cell Endocrinol. 2008 Sep 24; 292(1-2):50-62. Kundu P, Ciobotaru A, Foroughi S, Toro L, Stefani E, Eghbali M. PMID: 18611433; PMCID: PMC2893227.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansAnimalsCells
    80. Slo1 caveolin-binding motif, a mechanism of caveolin-1-Slo1 interaction regulating Slo1 surface expression. J Biol Chem. 2008 Feb 22; 283(8):4808-17. Alioua A, Lu R, Kumar Y, Eghbali M, Kundu P, Toro L, Stefani E. PMID: 18079116.
      View in: PubMed   Mentions: 41     Fields:    Translation:HumansAnimalsCells
    81. Increased 5-HT contractile response in late pregnant rat myometrium is associated with a higher density of 5-HT2A receptors. J Physiol. 2007 May 15; 581(Pt 1):91-7. Minosyan TY, Lu R, Eghbali M, Toro L, Stefani E. PMID: 17395633; PMCID: PMC2075229.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    82. Localization of sarcolemmal proteins to lipid rafts in the myocardium. Cell Calcium. 2007 Sep; 42(3):313-22. Cavalli A, Eghbali M, Minosyan TY, Stefani E, Philipson KD. PMID: 17320949; PMCID: PMC2724266.
      View in: PubMed   Mentions: 20     Fields:    Translation:AnimalsCells
    83. Heart hypertrophy during pregnancy: a better functioning heart? Trends Cardiovasc Med. 2006 Nov; 16(8):285-91. Eghbali M, Wang Y, Toro L, Stefani E. PMID: 17055385.
      View in: PubMed   Mentions: 27     Fields:    Translation:HumansAnimalsCells
    84. Heart estrogen receptor alpha: distinct membrane and nuclear distribution patterns and regulation by estrogen. J Mol Cell Cardiol. 2006 Sep; 41(3):496-510. Ropero AB, Eghbali M, Minosyan TY, Tang G, Toro L, Stefani E. PMID: 16876190.
      View in: PubMed   Mentions: 34     Fields:    Translation:AnimalsCells
    85. Kv channels contribute to nitric oxide- and atrial natriuretic peptide-induced relaxation of a rat conduit artery. J Pharmacol Exp Ther. 2006 Apr; 317(1):341-54. Tanaka Y, Tang G, Takizawa K, Otsuka K, Eghbali M, Song M, Nishimaru K, Shigenobu K, Koike K, Stefani E, Toro L. PMID: 16394199.
      View in: PubMed   Mentions: 14     Fields:    Translation:AnimalsCells
    86. MaxiK channel partners: physiological impact. J Physiol. 2006 Jan 01; 570(Pt 1):65-72. Lu R, Alioua A, Kumar Y, Eghbali M, Stefani E, Toro L. PMID: 16239267; PMCID: PMC1464300.
      View in: PubMed   Mentions: 116     Fields:    Translation:HumansAnimalsCells
    87. Alternative splicing of Slo channel gene programmed by estrogen, progesterone and pregnancy. FEBS Lett. 2005 Aug 29; 579(21):4856-60. Zhu N, Eghbali M, Helguera G, Song M, Stefani E, Toro L. PMID: 16102753.
      View in: PubMed   Mentions: 29     Fields:    Translation:HumansAnimalsCells
    88. Molecular and functional signature of heart hypertrophy during pregnancy. Circ Res. 2005 Jun 10; 96(11):1208-16. Eghbali M, Deva R, Alioua A, Minosyan TY, Ruan H, Wang Y, Toro L, Stefani E. PMID: 15905459.
      View in: PubMed   Mentions: 79     Fields:    Translation:Animals
    89. Functional and molecular evidence of MaxiK channel beta1 subunit decrease with coronary artery ageing in the rat. J Physiol. 2004 Sep 15; 559(Pt 3):849-62. Nishimaru K, Eghbali M, Lu R, Marijic J, Stefani E, Toro L. PMID: 15272033; PMCID: PMC1665167.
      View in: PubMed   Mentions: 36     Fields:    Translation:Animals
    90. Function and clustered expression of MaxiK channels in cerebral myocytes remain intact with aging. Exp Gerontol. 2004 May; 39(5):831-9. Nishimaru K, Eghbali M, Stefani E, Toro L. PMID: 15130678.
      View in: PubMed   Mentions: 13     Fields:    Translation:AnimalsCells
    91. Diminished surface clustering and increased perinuclear accumulation of large conductance Ca2+-activated K+ channel in mouse myometrium with pregnancy. J Biol Chem. 2003 Nov 14; 278(46):45311-7. Eghbali M, Toro L, Stefani E. PMID: 12952984.
      View in: PubMed   Mentions: 15     Fields:    Translation:AnimalsCells
    92. Conductance of GABAA channels activated by pentobarbitone in hippocampal neurons from newborn rats. J Physiol. 2003 Oct 01; 552(Pt 1):13-22. Eghbali M, Birnir B, Gage PW. PMID: 12897171; PMCID: PMC2343321.
      View in: PubMed   Mentions: 5     Fields:    Translation:AnimalsCells
    93. Effects of propofol on GABAA channel conductance in rat-cultured hippocampal neurons. Eur J Pharmacol. 2003 May 09; 468(2):75-82. Eghbali M, Gage PW, Birnir B. PMID: 12742514.
      View in: PubMed   Mentions: 8     Fields:    Translation:AnimalsCells
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