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Xia Yang

Photo of Xia Yang
Title(s)Professor, Integrative Biology And Physiology
SchoolCollege of Letters and Science
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    Other Positions
    Title(s)Professor, Molecular and Medical Pharmacology


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    Discriminating hormonal and sex chromosomal origins of sex differences in the septohippocampal circuit
    NIH R21MH129020May 6, 2022 - Apr 30, 2025
    Role: Co-Principal Investigator
    Spatiotemporal Molecular Substrates of TBI at Single Cell Resolution
    NIH R01NS117148Jul 1, 2020 - Mar 31, 2025
    Role: Principal Investigator
    Precision Medicine Approach: Using genomic information to guide TBI treatment
    NIH R01NS111378Jan 15, 2020 - Dec 31, 2024
    Role: Co-Principal Investigator
    Systems Genetics Dissection of Non-alcoholic Steatohepatitis
    NIH R01DK117850Jul 1, 2019 - Mar 31, 2028
    Role: Co-Principal Investigator
    Cell-specific novel genomic biomarkers of TBI pathology
    NIH R21NS103088May 15, 2017 - Apr 30, 2020
    Role: Principal Investigator
    DHA Reverses Gene Network Signatures of Fructose-induced Metabolic Syndrome
    NIH R01DK104363Dec 1, 2014 - Nov 30, 2020
    Role: Principal Investigator

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Multi-tissue multi-omics integration reveals tissue-specific pathways, gene networks and drug candidates for type 1 diabetes. Diabetologia. 2026 Apr 15. Blencowe M, Saleem Z, Liu R, Wang M, Tseng IH, Wier J, Mutter S, Vaida F, Guo Y, Sandholm N, Ackeifi C, Kaufman DL, Yang X. PMID: 41986815.
      View in: PubMed   Mentions:    Fields:    
    2. Neuronal and glial networks interact with traumatic brain injury to modulate cognition in ABCD study. NPJ Syst Biol Appl. 2026 Mar 13; 12(1). Cheng M, Mao M, Meng W, Jacobus J, Troyer EA, Delfel EL, Dennis EL, Wilde EA, Abildskov T, de Souza NL, Vaida F, Max JE, Yang X. PMID: 41826372; PMCID: PMC13128933.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    3. Estradiol treatment induces both shared and unique gene regulation and networks in adipose cell types of gonadectomized obese XX and XY mice. Biol Sex Differ. 2026 Feb 23; 17(1). Zhao Y, Liu R, Ng JP, Yu S, Ahn IS, Diamante G, Zhang G, Thorson A, Schaefers KP, Stafford JM, Yang X. PMID: 41731620; PMCID: PMC12930959.
      View in: PubMed   Mentions:    Fields:    
    4. Convergence and divergence of genes informed by common and rare variants of autism spectrum disorders in tissue-specific pathways and gene networks. Transl Psychiatry. 2026 Feb 06; 16(1). Gill C, Zuo Y, Ha DS, Littman R, Hong J, Cheng J, Blencowe M, Wang SS, Hong W, Wu YE, Yang X. PMID: 41651809; PMCID: PMC12923589.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    5. Comparative analysis of 105 datasets across species and tissues reveals differential transcriptomic responses to cannabinoids THC and CBD. J Cannabis Res. 2025 Dec 16; 8(1):13. Liu R, Kowal T, Chow C, Olson T, Nguyen E, Yang S, Lee J, Cai H, Yang X, Blencowe M. PMID: 41402937; PMCID: PMC12821297.
      View in: PubMed   Mentions:
    6. Multitissue single-cell analysis reveals differential cellular and molecular sensitivity between fructose and high-fat high-sucrose diets. Cell Rep. 2025 May 27; 44(5):115690. Chen YW, Ahn IS, Wang SS, Majid S, Diamante G, Cely I, Zhang G, Cabanayan A, Komzyuk S, Bonnett J, Arneson D, Yang X. PMID: 40349341; PMCID: PMC12182283.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    7. Circulating glycerate predicts resilience to fructose-induced hepatic steatosis. Cell Metab. 2025 May 06; 37(5):1223-1234.e5. Ramirez CB, Ahn IS, Rubtsova VI, Cely I, Le J, Kim J, Jung S, Kelly ME, Kim Y, Bae H, Song WS, Alam YH, Zhang G, Diamante G, Chao A, Hoffner L, Anica A, Le I, Lopez ML, Tamburini IJ, Moyer EM, Tsai A, Yang Q, Dai X, Piomelli D, Lee G, Yang X, Jang C. PMID: 40267913; PMCID: PMC12058382.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    8. Thyroid hormone T4 mitigates traumatic brain injury in mice by dynamically remodeling cell type specific genes, pathways, and networks in hippocampus and frontal cortex. Biochim Biophys Acta Mol Basis Dis. 2024 12; 1870(8):167344. Zhang G, Diamante G, Ahn IS, Palafox-Sanchez V, Cheng J, Cheng M, Ying Z, Wang SS, Abuhanna KD, Phi N, Arneson D, Cely I, Arellano K, Wang N, Zhang S, Peng C, Gomez-Pinilla F, Yang X. PMID: 39004380; PMCID: PMC12962868.
      View in: PubMed   Mentions: 8     Fields:    Translation:AnimalsCells
    9. Gene Regulatory Networks in Coronary Artery Disease. Curr Atheroscler Rep. 2023 12; 25(12):1013-1023. Cheng J, Cheng M, Lusis AJ, Yang X. PMID: 38008808; PMCID: PMC11466510.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    10. Systematic transcriptome-wide meta-analysis across endocrine disrupting chemicals reveals shared and unique liver pathways, gene networks, and disease associations. Environ Int. 2024 01; 183:108339. Zamora Z, Wang S, Chen YW, Diamante G, Yang X. PMID: 38043319; PMCID: PMC11216742.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimalsCells
    11. Editorial: Chordoma: advances in biology and clinical management. Front Oncol. 2023; 13:1175683. Gardner P, Bai J, Froelich S, Yang XR, Yang XR, Yang C. PMID: 37213281; PMCID: PMC10196620.
      View in: PubMed   Mentions: 1  
    12. Vaping in a Time of Pandemics: Risk Perception and Motivations for Electronic Cigarette Use. Nicotine Tob Res. 2023 01 05; 25(2):237-246. Yang XY, Kelly BC, Pawson M, Vuolo M. PMID: 35182425; PMCID: PMC9383448.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansPHPublic Health
    13. Systems spatiotemporal dynamics of traumatic brain injury at single-cell resolution reveals humanin as a therapeutic target. Cell Mol Life Sci. 2022 Aug 11; 79(9):480. Arneson D, Zhang G, Ahn IS, Ying Z, Diamante G, Cely I, Palafox-Sanchez V, Gomez-Pinilla F, Yang X. PMID: 35951114; PMCID: PMC9372016.
      View in: PubMed   Mentions: 22     Fields:    Translation:Animals
    14. IAPP-induced beta cell stress recapitulates the islet transcriptome in type 2 diabetes. Diabetologia. 2022 01; 65(1):173-187. Blencowe M, Furterer A, Wang Q, Gao F, Rosenberger M, Pei L, Nomoto H, Mawla AM, Huising MO, Coppola G, Yang X, Butler PC, Gurlo T. PMID: 34554282; PMCID: PMC8660728.
      View in: PubMed   Mentions: 21     Fields:    Translation:AnimalsCells
    15. Novel MAPK/AKT-impairing germline NRAS variant identified in a melanoma-prone family. Fam Cancer. 2022 07; 21(3):347-355. Brown KM, Xu M, Sargen M, Jang H, Zhang M, Zhang T, Zhu B, Jones K, Kim J, Mendoza L, Hayward NK, Tucker MA, Goldstein AM, Yang XR, Stewart DR, Hicks B, Consonni D, Pesatori AC, Fargnoli MC, Peris K, Stratigos A, Menin C, Ghiorzo P, Puig S, Nagore E, MelaNostrum Consortium, Andresson T, Nussinov R, Calista D, Landi MT. PMID: 34215961; PMCID: PMC8720902.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    16. Mergeomics 2.0: a web server for multi-omics data integration to elucidate disease networks and predict therapeutics. Nucleic Acids Res. 2021 07 02; 49(W1):W375-W387. Ding J, Blencowe M, Nghiem T, Ha SM, Chen YW, Li G, Yang X. PMID: 34048577; PMCID: PMC8262738.
      View in: PubMed   Mentions: 57     Fields:    Translation:Humans
    17. Conservation and divergence of vulnerability and responses to stressors between human and mouse astrocytes. Nat Commun. 2021 06 25; 12(1):3958. Li J, Pan L, Pembroke WG, Rexach JE, Godoy MI, Condro MC, Alvarado AG, Harteni M, Chen YW, Stiles L, Chen AY, Wanner IB, Yang X, Goldman SA, Geschwind DH, Kornblum HI, Zhang Y. PMID: 34172753; PMCID: PMC8233314.
      View in: PubMed   Mentions: 106     Fields:    Translation:HumansAnimalsCells
    18. Joint cell segmentation and cell type annotation for spatial transcriptomics. Mol Syst Biol. 2021 06; 17(6):e10108. Littman R, Hemminger Z, Foreman R, Arneson D, Zhang G, Gómez-Pinilla F, Yang X, Wollman R. PMID: 34057817; PMCID: PMC8166214.
      View in: PubMed   Mentions: 52     Fields:    Translation:AnimalsCells
    19. Tumor-Associated Stromal Cellular Density as a Predictor of Recurrence and Mortality in Breast Cancer: Results from Ethnically Diverse Study Populations. Cancer Epidemiol Biomarkers Prev. 2021 07; 30(7):1397-1407. Abubakar M, Zhang J, Ahearn TU, Koka H, Guo C, Lawrence SM, Mutreja K, Figueroa JD, Ying J, Lissowska J, Lyu N, Garcia-Closas M, Yang XR. PMID: 33952648; PMCID: PMC8254774.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansCells
    20. Single-Cell Study of Two Rat Models of Pulmonary Arterial Hypertension Reveals Connections to Human Pathobiology and Drug Repositioning. Am J Respir Crit Care Med. 2021 04 15; 203(8):1006-1022. Hong J, Arneson D, Umar S, Ruffenach G, Cunningham CM, Ahn IS, Diamante G, Bhetraratana M, Park JF, Said E, Huynh C, Le T, Medzikovic L, Humbert M, Soubrier F, Montani D, Girerd B, Trégouët DA, Channick R, Saggar R, Eghbali M, Yang X. PMID: 33021809; PMCID: PMC8048757.
      View in: PubMed   Mentions: 50     Fields:    Translation:HumansAnimalsCells
    21. Gut microbial taxa elevated by dietary sugar disrupt memory function. Transl Psychiatry. 2021 03 31; 11(1):194. Noble EE, Olson CA, Davis E, Tsan L, Chen YW, Schade R, Liu C, Suarez A, Jones RB, de La Serre C, Yang X, Hsiao EY, Kanoski SE. PMID: 33790226; PMCID: PMC8012713.
      View in: PubMed   Mentions: 47     Fields:    Translation:Animals
    22. Estrogen receptor alpha in the brain mediates tamoxifen-induced changes in physiology in mice. Elife. 2021 03 01; 10. Zhang Z, Park JW, Ahn IS, Diamante G, Sivakumar N, Arneson D, Yang X, van Veen JE, Correa SM. PMID: 33647234; PMCID: PMC7924955.
      View in: PubMed   Mentions: 22     Fields:    Translation:Animals
    23. Single-cell transcriptomic profiling of satellite glial cells in stellate ganglia reveals developmental and functional axial dynamics. Glia. 2021 05; 69(5):1281-1291. van Weperen VYH, Littman RJ, Arneson DV, Contreras J, Yang X, Ajijola OA. PMID: 33432730.
      View in: PubMed   Mentions: 20     Fields:    Translation:AnimalsCells
    24. Gene networks and pathways for plasma lipid traits via multitissue multiomics systems analysis. J Lipid Res. 2021; 62:100019. Blencowe M, Ahn IS, Saleem Z, Luk H, Cely I, Mäkinen VP, Zhao Y, Yang X. PMID: 33561811; PMCID: PMC7873371.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansAnimals
    25. Systems toxicogenomics of prenatal low-dose BPA exposure on liver metabolic pathways, gut microbiota, and metabolic health in mice. Environ Int. 2021 01; 146:106260. Diamante G, Cely I, Zamora Z, Ding J, Blencowe M, Lang J, Bline A, Singh M, Lusis AJ, Yang X. PMID: 33221593; PMCID: PMC7775895.
      View in: PubMed   Mentions: 34     Fields:    Translation:Animals
    26. MethylResolver-a method for deconvoluting bulk DNA methylation profiles into known and unknown cell contents. Commun Biol. 2020 08 03; 3(1):422. Arneson D, Yang X, Wang K. PMID: 32747663; PMCID: PMC7400544.
      View in: PubMed   Mentions: 39  Translation:HumansCells
    27. Oral 15-Hydroxyeicosatetraenoic Acid Induces Pulmonary Hypertension in Mice by Triggering T Cell-Dependent Endothelial Cell Apoptosis. Hypertension. 2020 09; 76(3):985-996. Ruffenach G, O'Connor E, Vaillancourt M, Hong J, Cao N, Sarji S, Moazeni S, Papesh J, Grijalva V, Cunningham CM, Shu L, Chattopadhyay A, Tiwari S, Mercier O, Perros F, Umar S, Yang X, Gomes AV, Fogelman AM, Reddy ST, Eghbali M. PMID: 32713273; PMCID: PMC8008496.
      View in: PubMed   Mentions: 18     Fields:    Translation:AnimalsCells
    28. Omega-3 fatty acids increase OXPHOS energy for immune therapy of Alzheimer disease patients. FASEB J. 2020 08; 34(8):9982-9994. Lau YCC, Ding JA, Simental A, Mirzoyan H, Lee W, Diamante G, Cely I, Tran M, Morselli M, Dang J, Kaczor-Urbanowicz KE, Sayre J, Stiles L, Yang X, Pellegrini M, Fiala M. PMID: 32614485.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    29. Behavioral and psychosocial correlates of road traffic injuries: evidence from a nationwide study on Chinese undergraduates. Traffic Inj Prev. 2020; 21(6):375-381. Wu D, Yang T, Yang XY, Hoe CH, Peng S, Yu L. PMID: 32496809.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    30. Multitissue Multiomics Systems Biology to Dissect Complex Diseases. Trends Mol Med. 2020 08; 26(8):718-728. Yang X. PMID: 32439301; PMCID: PMC7395877.
      View in: PubMed   Mentions: 37     Fields:    Translation:HumansAnimals
    31. Single-cell RNA-seq analysis of the brainstem of mutant SOD1 mice reveals perturbed cell types and pathways of amyotrophic lateral sclerosis. Neurobiol Dis. 2020 07; 141:104877. Liu W, Venugopal S, Majid S, Ahn IS, Diamante G, Hong J, Yang X, Chandler SH. PMID: 32360664; PMCID: PMC7519882.
      View in: PubMed   Mentions: 51     Fields:    Translation:AnimalsCells
    32. Therapeutic IDOL Reduction Ameliorates Amyloidosis and Improves Cognitive Function in APP/PS1 Mice. Mol Cell Biol. 2020 03 30; 40(8). Gao J, Littman R, Diamante G, Xiao X, Ahn IS, Yang X, Cole TA, Tontonoz P. PMID: 31964754; PMCID: PMC7108818.
      View in: PubMed   Mentions: 10     Fields:    Translation:AnimalsCells
    33. IDOL regulates systemic energy balance through control of neuronal VLDLR expression. Nat Metab. 2019 11; 1(11):1089-1100. Lee SD, Priest C, Bjursell M, Gao J, Arneson DV, Ahn IS, Diamante G, van Veen JE, Massa MG, Calkin AC, Kim J, Andersén H, Rajbhandari P, Porritt M, Carreras A, Ahnmark A, Seeliger F, Maxvall I, Eliasson P, Althage M, Åkerblad P, Lindén D, Cole TA, Lee R, Boyd H, Bohlooly-Y M, Correa SM, Yang X, Tontonoz P, Hong C. PMID: 32072135; PMCID: PMC7028310.
      View in: PubMed   Mentions: 15     Fields:    Translation:AnimalsCells
    34. Differential metabolic and multi-tissue transcriptomic responses to fructose consumption among genetically diverse mice. Biochim Biophys Acta Mol Basis Dis. 2020 01 01; 1866(1):165569. Zhang G, Byun HR, Ying Z, Blencowe M, Zhao Y, Hong J, Shu L, Chella Krishnan K, Gomez-Pinilla F, Yang X. PMID: 31669422; PMCID: PMC6993985.
      View in: PubMed   Mentions: 17     Fields:    Translation:AnimalsCells
    35. A typology of social capital and its mixed blessing for suicidal ideation: A multilevel study of college students. Soc Sci Med. 2019 12; 243:112640. Peng S, Yang XY, Yang XY, Rockett IRH. PMID: 31665656.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
    36. Systems genetics applications in metabolism research. Nat Metab. 2019 11; 1(11):1038-1050. Seldin M, Yang X, Lusis AJ. PMID: 32259026; PMCID: PMC7111511.
      View in: PubMed   Mentions: 28     Fields:    Translation:Humans
    37. Diesel exhaust particles dysregulate multiple immunological pathways in murine macrophages: Lessons from microarray and scRNA-seq technologies. Arch Biochem Biophys. 2019 12 15; 678:108116. Bhetraratana M, Orozco LD, Hong J, Diamante G, Majid S, Bennett BJ, Ahn IS, Yang X, Lusis AJ, Araujo JA. PMID: 31568751; PMCID: PMC7984963.
      View in: PubMed   Mentions: 5     Fields:    Translation:AnimalsCells
    38. Brain Trauma Disrupts Hepatic Lipid Metabolism: Blame It on Fructose? Mol Nutr Food Res. 2019 08; 63(15):e1801054. Rege SD, Royes L, Tsai B, Zhang G, Yang X, Gomez-Pinilla F. PMID: 31087499; PMCID: PMC6763319.
      View in: PubMed   Mentions: 10     Fields:    Translation:AnimalsCells
    39. Multi-omics integration reveals molecular networks and regulators of psoriasis. BMC Syst Biol. 2019 01 14; 13(1):8. Zhao Y, Jhamb D, Shu L, Arneson D, Rajpal DK, Yang X. PMID: 30642337; PMCID: PMC6332659.
      View in: PubMed   Mentions: 27     Fields:    Translation:Humans
    40. Tissue-specific pathways and networks underlying sexual dimorphism in non-alcoholic fatty liver disease. Biol Sex Differ. 2018 10 22; 9(1):46. Kurt Z, Barrere-Cain R, LaGuardia J, Mehrabian M, Pan C, Hui ST, Norheim F, Zhou Z, Hasin Y, Lusis AJ, Yang X. PMID: 30343673; PMCID: PMC6196429.
      View in: PubMed   Mentions: 44     Fields:    Translation:AnimalsCells
    41. Biglycan gene connects metabolic dysfunction with brain disorder. Biochim Biophys Acta Mol Basis Dis. 2018 12; 1864(12):3679-3687. Ying Z, Byun HR, Meng Q, Noble E, Zhang G, Yang X, Gomez-Pinilla F. PMID: 30291886; PMCID: PMC6239930.
      View in: PubMed   Mentions: 10     Fields:    Translation:AnimalsCells
    42. Single cell molecular alterations reveal target cells and pathways of concussive brain injury. Nat Commun. 2018 09 25; 9(1):3894. Arneson D, Zhang G, Ying Z, Zhuang Y, Byun HR, Ahn IS, Gomez-Pinilla F, Yang X. PMID: 30254269; PMCID: PMC6156584.
      View in: PubMed   Mentions: 111     Fields:    Translation:AnimalsCells
    43. System biology approach intersecting diet and cell metabolism with pathogenesis of brain disorders. Prog Neurobiol. 2018 10; 169:76-90. Gomez-Pinilla F, Yang X. PMID: 30059718; PMCID: PMC6231047.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimals
    44. Shared mechanisms among neurodegenerative diseases: from genetic factors to gene networks. J Genet. 2018 Jul; 97(3):795-806. Arneson D, Zhang Y, Yang X, Narayanan M. PMID: 30027910; PMCID: PMC6211183.
      View in: PubMed   Mentions: 33     Fields:    Translation:Humans
    45. The Memory of Environmental Chemical Exposure in C. elegans Is Dependent on the Jumonji Demethylases jmjd-2 and jmjd-3/utx-1. Cell Rep. 2018 05 22; 23(8):2392-2404. Camacho J, Truong L, Kurt Z, Chen YW, Morselli M, Gutierrez G, Pellegrini M, Yang X, Allard P. PMID: 29791850; PMCID: PMC6003705.
      View in: PubMed   Mentions: 38     Fields:    Translation:AnimalsCells
    46. Integration of Multi-omics Data from Mouse Diversity Panel Highlights Mitochondrial Dysfunction in Non-alcoholic Fatty Liver Disease. Cell Syst. 2018 Jan 24; 6(1):103-115.e7. Chella Krishnan K, Kurt Z, Barrere-Cain R, Sabir S, Das A, Floyd R, Vergnes L, Zhao Y, Che N, Charugundla S, Qi H, Zhou Z, Meng Y, Pan C, Seldin MM, Norheim F, Hui S, Reue K, Lusis AJ, Yang X. PMID: 29361464; PMCID: PMC5799036.
      View in: PubMed   Mentions: 91     Fields:    Translation:HumansAnimalsCells
    47. Nighttime eating and breast cancer among Chinese women in Hong Kong. Breast Cancer Res. 2017 03 17; 19(1):31. Li M, Tse LA, Chan WC, Kwok CH, Leung SL, Wu C, Yu WC, Lee PM, Tsang KH, Law SH, Vermeulen R, Gu F, Caporaso NE, Yu IT, Wang F, Yang XR, Yang XR. PMID: 28302140; PMCID: PMC5356318.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansPHPublic Health
    48. Traumatic Brain Injury Induces Genome-Wide Transcriptomic, Methylomic, and Network Perturbations in Brain and Blood Predicting Neurological Disorders. EBioMedicine. 2017 Feb; 16:184-194. Meng Q, Zhuang Y, Ying Z, Agrawal R, Yang X, Gomez-Pinilla F. PMID: 28174132; PMCID: PMC5474519.
      View in: PubMed   Mentions: 69     Fields:    Translation:HumansAnimalsCells
    49. Applications and Limitations of Mouse Models for Understanding Human Atherosclerosis. Cell Metab. 2017 02 07; 25(2):248-261. von Scheidt M, Zhao Y, Kurt Z, Pan C, Zeng L, Yang X, Schunkert H, Lusis AJ. PMID: 27916529; PMCID: PMC5484632.
      View in: PubMed   Mentions: 111     Fields:    Translation:HumansAnimalsCells
    50. Mergeomics: multidimensional data integration to identify pathogenic perturbations to biological systems. BMC Genomics. 2016 11 04; 17(1):874. Shu L, Zhao Y, Kurt Z, Byars SG, Tukiainen T, Kettunen J, Orozco LD, Pellegrini M, Lusis AJ, Ripatti S, Zhang B, Inouye M, Mäkinen VP, Yang X. PMID: 27814671; PMCID: PMC5097440.
      View in: PubMed   Mentions: 76     Fields:    Translation:HumansAnimals
    51. Mergeomics: a web server for identifying pathological pathways, networks, and key regulators via multidimensional data integration. BMC Genomics. 2016 09 09; 17(1):722. Arneson D, Bhattacharya A, Shu L, Mäkinen VP, Yang X. PMID: 27612452; PMCID: PMC5016927.
      View in: PubMed   Mentions: 34     Fields:    Translation:HumansCells
    52. Molecular and genetic inflammation networks in major human diseases. Mol Biosyst. 2016 07 19; 12(8):2318-41. Zhao Y, Forst CV, Sayegh CE, Wang IM, Yang X, Zhang B. PMID: 27303926; PMCID: PMC4955784.
      View in: PubMed   Mentions: 30     Fields:    Translation:HumansAnimals
    53. Systems Nutrigenomics Reveals Brain Gene Networks Linking Metabolic and Brain Disorders. EBioMedicine. 2016 May; 7:157-66. Meng Q, Ying Z, Noble E, Zhao Y, Agrawal R, Mikhail A, Zhuang Y, Tyagi E, Zhang Q, Lee JH, Morselli M, Orozco L, Guo W, Kilts TM, Zhu J, Zhang B, Pellegrini M, Xiao X, Young MF, Gomez-Pinilla F, Yang X. PMID: 27322469; PMCID: PMC4909610.
      View in: PubMed   Mentions: 44     Fields:    Translation:HumansAnimals
    54. Network-Based Identification and Prioritization of Key Regulators of Coronary Artery Disease Loci. Arterioscler Thromb Vasc Biol. 2016 05; 36(5):928-41. Zhao Y, Chen J, Freudenberg JM, Meng Q, Rajpal DK, Yang X. PMID: 26966275; PMCID: PMC5576868.
      View in: PubMed   Mentions: 43     Fields:    Translation:HumansAnimalsCells
    55. Prediction of Causal Candidate Genes in Coronary Artery Disease Loci. Arterioscler Thromb Vasc Biol. 2015 Oct; 35(10):2207-17. Brænne I, Civelek M, Vilne B, Di Narzo A, Johnson AD, Zhao Y, Reiz B, Codoni V, Webb TR, Foroughi Asl H, Hamby SE, Zeng L, Trégouët DA, Hao K, Topol EJ, Schadt EE, Yang X, Samani NJ, Björkegren JL, Erdmann J, Schunkert H, Lusis AJ, Leducq Consortium CAD Genomics‡. PMID: 26293461; PMCID: PMC4583353.
      View in: PubMed   Mentions: 72     Fields:    Translation:HumansCells
    56. Integrative network analysis reveals molecular mechanisms of blood pressure regulation. Mol Syst Biol. 2015 Apr 16; 11(1):799. Huan T, Meng Q, Saleh MA, Norlander AE, Joehanes R, Zhu J, Chen BH, Zhang B, Johnson AD, Ying S, Courchesne P, Raghavachari N, Wang R, Liu P, International Consortium for Blood Pressure GWAS (ICBP), O'Donnell CJ, Vasan R, Munson PJ, Madhur MS, Harrison DG, Yang X, Levy D. PMID: 25882670; PMCID: PMC4422556.
      View in: PubMed   Mentions: 71     Fields:    Translation:HumansAnimalsCells
    57. Familial risks and estrogen receptor-positive breast cancer in Hong Kong Chinese women. PLoS One. 2015; 10(3):e0120741. Tse LA, Li M, Chan WC, Kwok CH, Leung SL, Wu C, Yu IT, Yu WC, Lao X, Wang X, Wong CK, Lee PM, Wang F, Yang XR, Yang XR. PMID: 25756203; PMCID: PMC4355610.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
    58. A systems genetics study of swine illustrates mechanisms underlying human phenotypic traits. BMC Genomics. 2015 Feb 14; 16:88. Zhu J, Chen C, Yang B, Guo Y, Ai H, Ren J, Peng Z, Tu Z, Yang X, Meng Q, Friend S, Huang L. PMID: 25765547; PMCID: PMC4336704.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansAnimals
    59. Dissecting the roles of microRNAs in coronary heart disease via integrative genomic analyses. Arterioscler Thromb Vasc Biol. 2015 Apr; 35(4):1011-21. Huan T, Rong J, Tanriverdi K, Meng Q, Bhattacharya A, McManus DD, Joehanes R, Assimes TL, McPherson R, Samani NJ, Erdmann J, Schunkert H, Courchesne P, Munson PJ, Johnson AD, O'Donnell CJ, Zhang B, Larson MG, Freedman JE, Levy D, Yang X. PMID: 25657313; PMCID: PMC4376567.
      View in: PubMed   Mentions: 32     Fields:    Translation:Humans
    60. Shared molecular pathways and gene networks for cardiovascular disease and type 2 diabetes mellitus in women across diverse ethnicities. Circ Cardiovasc Genet. 2014 Dec; 7(6):911-9. Chan KH, Huang YT, Meng Q, Wu C, Reiner A, Sobel EM, Tinker L, Lusis AJ, Yang X, Liu S. PMID: 25371518.
      View in: PubMed   Mentions: 35     Fields:    Translation:Humans
    61. Variants associated with susceptibility to pancreatic cancer and melanoma do not reciprocally affect risk. Cancer Epidemiol Biomarkers Prev. 2014 Jun; 23(6):1121-4. Wu L, Goldstein AM, Yu K, Yang XR, Yang XR, Rabe KG, Arslan AA, Canzian F, Wolpin BM, Stolzenberg-Solomon R, Amundadottir LT, Petersen GM. PMID: 24642353; PMCID: PMC4120837.
      View in: PubMed   Mentions: 13     Fields:    Translation:Humans
    62. Constitutional promoter methylation and risk of familial melanoma. Epigenetics. 2014 May; 9(5):685-92. Hyland PL, Burke LS, Pfeiffer RM, Rotunno M, Sun D, Patil P, Wu X, Tucker MA, Goldstein AM, Yang XR, Yang XR. PMID: 24762620; PMCID: PMC4063827.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansCells
    63. Systems Biology Approaches and Applications in Obesity, Diabetes, and Cardiovascular Diseases. Curr Cardiovasc Risk Rep. 2013 Feb; 7(1):73-83. Meng Q, Mäkinen VP, Luk H, Yang X. PMID: 23326608; PMCID: PMC3543610.
      View in: PubMed   Mentions: 21  
    64. Functional genomics- and network-driven systems biology approaches for pharmacogenomics and toxicogenomics. Curr Drug Metab. 2012 Sep 01; 13(7):952-67. Yang X, Zhang B, Zhu J. PMID: 22591344.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansAnimals
    65. Use of functional genomics to identify candidate genes underlying human genetic association studies of vascular diseases. Arterioscler Thromb Vasc Biol. 2012 Feb; 32(2):216-22. Yang X. PMID: 22258904.
      View in: PubMed   Mentions: 10     Fields:    Translation:Humans
    66. Associations of 9p21 variants with cutaneous malignant melanoma, nevi, and pigmentation phenotypes in melanoma-prone families with and without CDKN2A mutations. Fam Cancer. 2010 Dec; 9(4):625-33. Yang XR, Yang XR, Liang X, Pfeiffer RM, Wheeler W, Maeder D, Burdette L, Yeager M, Chanock S, Tucker MA, Goldstein AM. PMID: 20574843; PMCID: PMC3233727.
      View in: PubMed   Mentions: 24     Fields:    Translation:HumansCells
    67. Identification of modifier genes for cutaneous malignant melanoma in melanoma-prone families with and without CDKN2A mutations. Int J Cancer. 2009 Dec 15; 125(12):2912-7. Yang XR, Yang XR, Pfeiffer RM, Wheeler W, Yeager M, Chanock S, Tucker MA, Goldstein AM. PMID: 19626699; PMCID: PMC2767393.
      View in: PubMed   Mentions: 21     Fields:    Translation:Humans
    68. Association of human leukocyte antigens with nasopharyngeal carcinoma in high-risk multiplex families in Taiwan. Hum Immunol. 2009 Nov; 70(11):910-4. Yu KJ, Gao X, Chen CJ, Yang XR, Yang XR, Diehl SR, Goldstein A, Hsu WL, Liang XS, Marti D, Liu MY, Chen JY, Carrington M, Hildesheim A. PMID: 19683024; PMCID: PMC2764811.
      View in: PubMed   Mentions: 15     Fields:    Translation:Humans
    69. Estimating age-specific breast cancer risks: a descriptive tool to identify age interactions. Cancer Causes Control. 2007 May; 18(4):439-47. Anderson WF, Matsuno RK, Sherman ME, Lissowska J, Gail MH, Brinton LA, Yang XR, Yang XR, Peplonska B, Chen BE, Rosenberg PS, Chatterjee N, Szeszenia-Dabrowska N, Bardin-Mikolajczak A, Zatonski W, Devesa SS, García-Closas M. PMID: 17216325.
      View in: PubMed   Mentions: 27     Fields:    Translation:Humans
    70. Construction and validation of tissue microarrays of ductal carcinoma in situ and terminal duct lobular units associated with invasive breast carcinoma. Diagn Mol Pathol. 2006 Sep; 15(3):157-61. Yang XR, Yang XR, Charette LA, Garcia-Closas M, Lissowska J, Paal E, Sidawy M, Hewitt SM, Rimm DL, Sherman ME. PMID: 16932071.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
    71. Genetic variation of Cytochrome P450 1B1 (CYP1B1) and risk of breast cancer among Polish women. Pharmacogenet Genomics. 2006 Aug; 16(8):547-53. Gaudet MM, Chanock S, Lissowska J, Berndt SI, Yang XR, Yang XR, Peplonska B, Brinton LA, Welch R, Yeager M, Bardin-Mikolajczak A, Sherman ME, Sutter TR, Garcia-Closas M. PMID: 16847423.
      View in: PubMed   Mentions: 11     Fields:    Translation:Humans
    72. Identification of susceptibility loci for complex diseases in a case-control association study using the Genetic Analysis Workshop 14 dataset. BMC Genet. 2005 Dec 30; 6 Suppl 1:S102. Kerstann KF, Jacobs K, Yang XR, Yang XR, Bergen AW, Goldin LR, Goldstein AM. PMID: 16451558; PMCID: PMC1866837.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    73. Linkage analysis of the GAW14 simulated dataset with microsatellite and single-nucleotide polymorphism markers in large pedigrees. BMC Genet. 2005 Dec 30; 6 Suppl 1:S14. Yang XR, Yang XR, Jacobs K, Kerstann KF, Bergen AW, Goldstein AM, Goldin LR. PMID: 16451599; PMCID: PMC1866796.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
    74. Evaluation of risk factors for nasopharyngeal carcinoma in high-risk nasopharyngeal carcinoma families in Taiwan. Cancer Epidemiol Biomarkers Prev. 2005 Apr; 14(4):900-5. Yang XR, Yang XR, Diehl S, Pfeiffer R, Chen CJ, Hsu WL, Dosemeci M, Cheng YJ, Sun B, Goldstein AM, Hildesheim A, Chinese and American Genetic Epidemiology of NPC Study Team. PMID: 15826929.
      View in: PubMed   Mentions: 31     Fields:    Translation:HumansAnimalsPHPublic Health
    75. Genomic regions linked to alcohol consumption in the Framingham Heart Study. BMC Genet. 2003 Dec 31; 4 Suppl 1:S101. Bergen AW, Yang XR, Bai Y, Beerman MB, Goldstein AM, Goldin LR, Framingham Heart Study. PMID: 14975169; PMCID: PMC1866439.
      View in: PubMed   Mentions: 28     Fields:    Translation:HumansCells
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