Stanley Thomas Carmichael

Title(s)Department Chair, Neurology
ORCID ORCID Icon0000-0002-1169-9203 Additional info
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    Title(s)Professor, Neurology

    Title(s)Professor, Neurobiology

    Collapse Biography 
    Collapse Education and Training
    Washington University School of Medicine, St. Louis, MOMD06/1996Medicine
    Washington University School of Medicine, St. Louis, MOPhD06/1993Neuroscience
    UCLA, Los Angeles, CABS06/1986Biology

    Collapse Overview 
    Collapse Overview
    S. Thomas Carmichael is a neurologist and neuroscientist in the Departments of Neurology and of Neurobiology at the David Geffen School of Medicine at UCLA. Dr. Carmichael is Professor and Chair of the Department of Neurology, co-Director of the UCLA Broad Stem Cell Center and co-Director of the Regenerative Medicine Theme in the David Geffen School of Medicine. He also holds the Frances Stark Chair in Neurology. Dr. Carmichael has active laboratory and clinical interests in stroke and neurorehabilitation and how the brain repairs from injury. He received his M.D. and Ph.D. degrees from Washington University School of Medicine in 1993 and 1994, and completed a Neurology residency at Washington University School of Medicine, serving as Chief Resident. Dr. Carmichael was a Howard Hughes Medical Institute postdoctoral fellow at UCLA from 1998-2001. He has been on the UCLA faculty since 2001. Dr. Carmichael’s laboratory studies the molecular and cellular mechanisms of neural repair after stroke and other forms of brain injury. This research focuses on the processes of axonal sprouting and neural stem cell and progenitor responses after stroke, and on neural stem cell transplantation. Dr. Carmichael is an attending physician on the General Neurology and outpatient clinical services at UCLA.

    Dr. Carmichael has published important papers on stroke recovery that have defined mechanisms of plasticity and repair. These include the fact that the stroke produces partially damage circuits that limit recovery, but can be restored to normal functioning with newly applied experimental drugs. His work has identified a novel brain “growth program” that is activated by stroke and leads to the formation of new connections. These studies have also identified how this growth program changes with age, and how specific molecules in the aged brain block the formation of new connections and of recovery.
    This and other work has led to new directions in stroke therapeutics, including therapies with stem cell and tissue engineering applications. Dr. Carmichael is in the midst of stroke stem cell development applications with the FDA and with biotechnology companies.

    Collapse Research 
    Collapse Research Activities and Funding
    The role of pericytes in scar formation following stroke and myocardial infarction
    NIH R01NS112256Mar 1, 2020 - Feb 28, 2025
    Role: Principal Investigator
    ASNR Annual Meeting
    NIH R13HD101240Sep 25, 2019 - Aug 31, 2020
    Role: Principal Investigator
    iPS-Glial Restricted Progenitors in White Matter Repair for Stroke
    NIH R01NS103788May 15, 2018 - Feb 28, 2023
    Role: Principal Investigator
    Mechanisms of White Matter Repair in Subcortical White Matter Ischemia
    NIH R37NS102185Apr 1, 2018 - Mar 31, 2022
    Role: Principal Investigator
    Molecular Mechanisms of Axonal Sprouting and Recovery from Stroke
    NIH R01NS085019May 15, 2014 - Apr 30, 2019
    Role: Principal Investigator
    Molecular Signaling within a Regenerative Neurovascular Niche after Stroke
    NIH R01NS081055Jul 1, 2013 - Jun 30, 2018
    Role: Principal Investigator
    Mechanisms of Axonal Sprouting and Recovery in Intracerebral Hemorrhage
    NIH R01NS077521May 1, 2012 - Apr 30, 2017
    Role: Principal Investigator
    Mechanisms of Neural Repair in White Matter Stroke
    NIH R01NS071481Jul 15, 2010 - Jun 30, 2015
    Role: Principal Investigator
    Stroke Stem Cell/Hydrogel Therapy
    NIH R21NS067692Aug 15, 2009 - Jan 31, 2012
    Role: Principal Investigator
    Neurology Physician Research Training Grant
    NIH R25NS065723Mar 4, 2009 - Jun 30, 2025
    Role: Principal Investigator
    Mechanisms of Neuronal Regeneration after Stroke in a Novel Neurovascular Niche
    NIH R01NS053957Jul 1, 2006 - Jun 30, 2012
    Role: Principal Investigator
    Mechanisms of Axonal Sprouting After Stroke
    NIH R01NS045729Aug 15, 2004 - May 31, 2009
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Evaluation of two eco-friendly neutralizers for a spectrum of tissue fixatives for biomedical applications. Future Sci OA. 2018 Sep; 4(8):FSO329. Prakash R, Carmichael ST. PMID: 30271616; PMCID: PMC6153453.
      View in: PubMed   Mentions:
    2. Customized Brain Cells for Stroke Patients Using Pluripotent Stem Cells. Stroke. 2018 05; 49(5):1091-1098. Kokaia Z, Llorente IL, Carmichael ST. PMID: 29669871; PMCID: PMC5916498.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansCells
    3. Hydrogels for brain repair after stroke: an emerging treatment option. Curr Opin Biotechnol. 2016 08; 40:155-163. Nih LR, Carmichael ST, Segura T. PMID: 27162093; PMCID: PMC4975623.
      View in: PubMed   Mentions: 35     Fields:    Translation:HumansAnimals
    4. The 3 Rs of Stroke Biology: Radial, Relayed, and Regenerative. Neurotherapeutics. 2016 Apr; 13(2):348-59. Carmichael ST. PMID: 26602550; PMCID: PMC4824028.
      View in: PubMed   Mentions: 39     Fields:    Translation:Humans
    5. Molecular, cellular and functional events in axonal sprouting after stroke. Exp Neurol. 2017 Jan; 287(Pt 3):384-394. Carmichael ST, Kathirvelu B, Schweppe CA, Nie EH. PMID: 26874223; PMCID: PMC4980303.
      View in: PubMed   Mentions: 87     Fields:    Translation:HumansAnimalsCells
    6. The promise of neuro-recovery after stroke: introduction. Stroke. 2013 Jun; 44(6 Suppl 1):S103. Carmichael ST, Krakauer JW. PMID: 23709697.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimals
    7. Opinion & special articles: a guide from fellowship to faculty: Nietzsche and the academic neurologist. Neurology. 2012 Oct 02; 79(14):e116-9. Carmichael ST. PMID: 23033506; PMCID: PMC3525297.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    8. Brain excitability in stroke: the yin and yang of stroke progression. Arch Neurol. 2012 Feb; 69(2):161-7. Carmichael ST. PMID: 21987395; PMCID: PMC4698890.
      View in: PubMed   Mentions: 105     Fields:    Translation:HumansCells
    9. Targets for neural repair therapies after stroke. Stroke. 2010 Oct; 41(10 Suppl):S124-6. Carmichael ST. PMID: 20876486; PMCID: PMC2955885.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansCells
    10. Translating the frontiers of brain repair to treatments: starting not to break the rules. Neurobiol Dis. 2010 Feb; 37(2):237-42. Carmichael ST. PMID: 19770043; PMCID: PMC2818165.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansAnimals
    11. Genomic profiles of damage and protection in human intracerebral hemorrhage. J Cereb Blood Flow Metab. 2008 Nov; 28(11):1860-75. Carmichael ST, Vespa PM, Saver JL, Coppola G, Geschwind DH, Starkman S, Miller CM, Kidwell CS, Liebeskind DS, Martin NA. PMID: 18628781; PMCID: PMC2745827.
      View in: PubMed   Mentions: 39     Fields:    Translation:HumansAnimalsCells
    12. Image-guided endoscopic evacuation of spontaneous intracerebral hemorrhage. Surg Neurol. 2008 May; 69(5):441-6; discussion 446. Miller CM, Vespa P, Saver JL, Kidwell CS, Carmichael ST, Alger J, Frazee J, Starkman S, Liebeskind D, Nenov V, Elashoff R, Martin N. PMID: 18424298; PMCID: PMC4160887.
      View in: PubMed   Mentions: 27     Fields:    Translation:HumansCTClinical Trials
    13. Themes and strategies for studying the biology of stroke recovery in the poststroke epoch. Stroke. 2008 Apr; 39(4):1380-8. Carmichael ST. PMID: 18309162; PMCID: PMC2711539.
      View in: PubMed   Mentions: 47     Fields:    Translation:HumansAnimals
    14. The response of the aged brain to stroke: too much, too soon? Curr Neurovasc Res. 2007 Aug; 4(3):216-27. Popa-Wagner A, Carmichael ST, Kokaia Z, Kessler C, Walker LC. PMID: 17691975.
      View in: PubMed   Mentions: 68     Fields:    Translation:HumansAnimals
    15. Cellular and molecular mechanisms of neural repair after stroke: making waves. Ann Neurol. 2006 May; 59(5):735-42. Carmichael ST. PMID: 16634041.
      View in: PubMed   Mentions: 231     Fields:    Translation:HumansAnimalsCells
    16. Rodent models of focal stroke: size, mechanism, and purpose. NeuroRx. 2005 Jul; 2(3):396-409. Carmichael ST. PMID: 16389304; PMCID: PMC1144484.
      View in: PubMed   Mentions: 294     Fields:    Translation:HumansAnimalsCells
    17. Growth-associated gene expression after stroke: evidence for a growth-promoting region in peri-infarct cortex. Exp Neurol. 2005 Jun; 193(2):291-311. Carmichael ST, Archibeque I, Luke L, Nolan T, Momiy J, Li S. PMID: 15869933.
      View in: PubMed   Mentions: 175     Fields:    Translation:Animals
    18. Evolution of diaschisis in a focal stroke model. Stroke. 2004 Mar; 35(3):758-63. Carmichael ST, Tatsukawa K, Katsman D, Tsuyuguchi N, Kornblum HI. PMID: 14963280.
      View in: PubMed   Mentions: 57     Fields:    Translation:Animals
    19. Gene expression changes after focal stroke, traumatic brain and spinal cord injuries. Curr Opin Neurol. 2003 Dec; 16(6):699-704. Carmichael ST. PMID: 14624079.
      View in: PubMed   Mentions: 35     Fields:    Translation:HumansAnimalsCells
    20. Plasticity of cortical projections after stroke. Neuroscientist. 2003 Feb; 9(1):64-75. Carmichael ST. PMID: 12580341.
      View in: PubMed   Mentions: 136     Fields:    Translation:HumansAnimalsCells
    21. Synchronous neuronal activity is a signal for axonal sprouting after cortical lesions in the adult. J Neurosci. 2002 Jul 15; 22(14):6062-70. Carmichael ST, Chesselet MF. PMID: 12122067; PMCID: PMC6757933.
      View in: PubMed   Mentions: 143     Fields:    Translation:AnimalsCells
    22. New laboratory start-up in the 21st century. Trends Neurosci. 2002 Jun; 25(6):287-8. Carmichael ST. PMID: 12086740.
      View in: PubMed   Mentions:    Fields:    Translation:Animals
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