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Jessica Rexach

Title(s)Assistant Professor-in-Residence, Neurology
SchoolMedicine
Phone66814
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    Collapse Research 
    Collapse Research Activities and Funding
    Single cell and tissue level functional genomic analysis of astrocyte-related mechanisms in tauopathy
    NIH/NINDS K08NS105916Sep 15, 2019 - Aug 31, 2024
    Role: Principal Investigator
    The story of methyl-CpG binding protein 2 glycosylation
    NIH/NINDS F31NS056525Sep 1, 2006 - Aug 31, 2010
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Ngo KJ, Rexach JE, Lee H, Petty LE, Perlman S, Valera JM, Deignan JL, Mao Y, Aker M, Posey JE, Jhangiani SN, Coban-Akdemir ZH, Boerwinkle E, Muzny D, Nelson AB, Hassin-Baer S, Poke G, Neas K, Geschwind MD, Grody WW, Gibbs R, Geschwind DH, Lupski JR, Below JE, Nelson SF, Fogel BL. A diagnostic ceiling for exome sequencing in cerebellar ataxia and related neurological disorders. Hum Mutat. 2019 Nov 06. PMID: 31692161.
      View in: PubMed
    2. Xiao C, M Binkley E, Rexach J, Knight-Johnson A, Khemani P, Fogel BL, Das S, M Stone E, Gomez CM. A family with spinocerebellar ataxia and retinitis pigmentosa attributed to an ELOVL4 mutation. Neurol Genet. 2019 Oct; 5(5):e357. PMID: 31750392.
      View in: PubMed
    3. Rexach J, Lee H, Martinez-Agosto JA, Németh AH, Fogel BL. Clinical application of next-generation sequencing to the practice of neurology. Lancet Neurol. 2019 May; 18(5):492-503. PMID: 30981321.
      View in: PubMed
    4. Lee H, Martinez-Agosto JA, Rexach J, Fogel BL. Next generation sequencing in clinical diagnosis. Lancet Neurol. 2019 May; 18(5):426. PMID: 30981320.
      View in: PubMed
    5. Swarup V, Hinz FI, Rexach JE, Noguchi KI, Toyoshiba H, Oda A, Hirai K, Sarkar A, Seyfried NT, Cheng C, Haggarty SJ, Grossman M, Van Deerlin VM, Trojanowski JQ, Lah JJ, Levey AI, Kondou S, Geschwind DH. Identification of evolutionarily conserved gene networks mediating neurodegenerative dementia. Nat Med. 2019 01; 25(1):152-164. PMID: 30510257.
      View in: PubMed
    6. Wang AC, Jensen EH, Rexach JE, Vinters HV, Hsieh-Wilson LC. Loss of O-GlcNAc glycosylation in forebrain excitatory neurons induces neurodegeneration. Proc Natl Acad Sci U S A. 2016 12 27; 113(52):15120-15125. PMID: 27956640.
      View in: PubMed
    7. Trikamji B, Rexach J, Mishra SK. A Case of Spinocerebellar Ataxia With a Reversible Splenium Lesion Due to Malnutrition and Vitamin Deficiency. J Clin Neuromuscul Dis. 2015 Dec; 17(2):95-7. PMID: 26583499.
      View in: PubMed
    8. Clark PM, Rexach JE, Hsieh-Wilson LC. Visualization of O-GlcNAc glycosylation stoichiometry and dynamics using resolvable poly(ethylene glycol) mass tags. Curr Protoc Chem Biol. 2013; 5(4):281-302. PMID: 24391098.
      View in: PubMed
    9. Rexach JE, Clark PM, Mason DE, Neve RL, Peters EC, Hsieh-Wilson LC. Dynamic O-GlcNAc modification regulates CREB-mediated gene expression and memory formation. Nat Chem Biol. 2012 Jan 22; 8(3):253-61. PMID: 22267118.
      View in: PubMed
    10. Rexach JE, Rogers CJ, Yu SH, Tao J, Sun YE, Hsieh-Wilson LC. Quantification of O-glycosylation stoichiometry and dynamics using resolvable mass tags. Nat Chem Biol. 2010 Sep; 6(9):645-51. PMID: 20657584.
      View in: PubMed
    11. Rexach JE, Clark PM, Hsieh-Wilson LC. Chemical approaches to understanding O-GlcNAc glycosylation in the brain. Nat Chem Biol. 2008 Feb; 4(2):97-106. PMID: 18202679.
      View in: PubMed
    12. Khidekel N, Ficarro SB, Clark PM, Bryan MC, Swaney DL, Rexach JE, Sun YE, Coon JJ, Peters EC, Hsieh-Wilson LC. Probing the dynamics of O-GlcNAc glycosylation in the brain using quantitative proteomics. Nat Chem Biol. 2007 Jun; 3(6):339-48. PMID: 17496889.
      View in: PubMed