Rosalie E Lawrence

Title(s)Assistant Professor, Biological Chemistry
SchoolMedicine
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Allosteric disordering of eIF2B regulates the integrated stress response. Nat Chem Biol. 2026 Jun 29. Dalwadi U, Subramanian A, Deal A, Conrad JE, Nadjsombati T, Venkatesh M, Boone M, Egea PF, He L, Jain N, Lee DJ, Liu Y, Reineke LC, Saito K, Talledge N, Toutkoushian H, Le Vasseur M, Zappa F, de Groot RJ, Acosta-Alvear D, Arthur CP, Nunnari J, Marqusee S, Lawrence RE, Costa-Mattioli M, Crawford JJ, van Kuppeveld FJM, Croll TI, Walter P, Frost A. PMID: 42373951.
      View in: PubMed   Mentions: 1     Fields:    
    2. CRISPR screens in iPSC-derived neurons reveal principles of tau proteostasis. Cell. 2026 Mar 05; 189(5):1517-1534.e19. Samelson AJ, Ariqat N, McKetney J, Rohanitazangi G, Parra Bravo C, Bose RS, Travaglini KJ, Lam VL, Goodness D, Ta T, Dixon G, Marzette E, Jin J, Tian R, Tse E, Abskharon R, Pan HS, Carroll EC, Lawrence RE, Gestwicki JE, Rexach JE, Eisenberg DS, Kanaan NM, Southworth DR, Gross JD, Gan L, Swaney DL, Kampmann M. PMID: 41610849; PMCID: PMC12978015.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCells
    3. CRISPR screens in iPSC-derived neurons reveal principles of tau proteostasis. bioRxiv. 2024 Nov 04. Samelson AJ, Ariqat N, McKetney J, Rohanitazangi G, Bravo CP, Bose R, Travaglini KJ, Lam VL, Goodness D, Dixon G, Marzette E, Jin J, Tian R, Tse E, Abskharon R, Pan H, Carroll EC, Lawrence RE, Gestwicki JE, Eisenberg D, Kanaan NM, Southworth DR, Gross JD, Gan L, Swaney DL, Kampmann M. PMID: 37398204; PMCID: PMC10312804.
      View in: PubMed   Mentions: 1  
    4. A helical fulcrum in eIF2B coordinates allosteric regulation of stress signaling. Nat Chem Biol. 2024 04; 20(4):422-431. Lawrence RE, Shoemaker SR, Deal A, Sangwan S, Anand AA, Wang L, Marqusee S, Walter P. PMID: 37945896; PMCID: PMC10972756.
      View in: PubMed   Mentions: 6     Fields:    Translation:Cells
    5. A point mutation in the nucleotide exchange factor eIF2B constitutively activates the integrated stress response by allosteric modulation. Elife. 2022 04 13; 11. Boone M, Wang L, Lawrence RE, Frost A, Walter P, Schoof M. PMID: 35416150; PMCID: PMC9132573.
      View in: PubMed   Mentions: 4     Fields:    Translation:Cells
    6. Viral evasion of the integrated stress response through antagonism of eIF2-P binding to eIF2B. Nat Commun. 2021 12 07; 12(1):7103. Schoof M, Wang L, Cogan JZ, Lawrence RE, Boone M, Wuerth JD, Frost A, Walter P. PMID: 34876554; PMCID: PMC8651678.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansCells
    7. Structural mechanism for amino acid-dependent Rag GTPase nucleotide state switching by SLC38A9. Nat Struct Mol Biol. 2020 11; 27(11):1017-1023. Fromm SA, Lawrence RE, Hurley JH. PMID: 32868926; PMCID: PMC7644641.
      View in: PubMed   Mentions: 33     Fields:    Translation:HumansCells
    8. Structural mechanism of a Rag GTPase activation checkpoint by the lysosomal folliculin complex. Science. 2019 11 22; 366(6468):971-977. Lawrence RE, Fromm SA, Fu Y, Yokom AL, Kim DJ, Thelen AM, Young LN, Lim CY, Samelson AJ, Hurley JH, Zoncu R. PMID: 31672913; PMCID: PMC6945816.
      View in: PubMed   Mentions: 108     Fields:    Translation:HumansCells
    9. Positive and Negative Regulation of the Master Metabolic Regulator mTORC1 by Two Families of Legionella pneumophila Effectors. Cell Rep. 2017 Nov 21; 21(8):2031-2038. De Leon JA, Qiu J, Nicolai CJ, Counihan JL, Barry KC, Xu L, Lawrence RE, Castellano BM, Zoncu R, Nomura DK, Luo ZQ, Vance RE. PMID: 29166595; PMCID: PMC5726772.
      View in: PubMed   Mentions: 40     Fields:    Translation:Cells
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