Thomas G Graeber

Title(s)Professor, Molecular and Medical Pharmacology
SchoolMedicine
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    Collapse Research 
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    Metabolic and epigenetic reprogramming of vital organs in SARS-CoV-2 induced systemic toxicity
    NIH R01DK132735Sep 17, 2021 - Aug 31, 2024
    Role: Co-Principal Investigator
    Targeting Genomic Instability in Lethal Neuroendocrine Prostate Cancer
    NIH R01CA222877Jun 6, 2018 - May 31, 2023
    Role: Principal Investigator
    Mammalian models for integrated metabolic and molecular profiling of malignant glioma
    NIH R01CA227089Jun 6, 2018 - May 31, 2023
    Role: Co-Principal Investigator
    Quantitative Mass Spectrometer for Targeted and Global Proteomics, Metabolomics
    NIH S10OD016387Jul 1, 2013 - Jun 30, 2014
    Role: Principal Investigator
    Diagnosing Emergence of Kinase Inhibitor Resistance on a Microchip
    NIH R21CA169993Aug 24, 2012 - Jul 31, 2014
    Role: Principal Investigator
    Profiling of Protein Modifications by Mass Spectrometry
    NIH K22HG002807May 12, 2003 - Mar 31, 2008
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Combined inhibition of de novo glutathione and nucleotide biosynthesis is synthetically lethal in glioblastoma. Cell Rep. 2025 May 27; 44(5):115596. Udutha S, Taglang C, Batsios G, Gillespie AM, Tran M, Hoeve JT, Graeber TG, Viswanath P. PMID: 40253695.
      View in: PubMed   Mentions:    Fields:    
    2. Supercharged NK cells, unlike primary activated NK cells, effectively target ovarian cancer cells irrespective of MHC-class I expression. BMJ Oncol. 2025; 4(1):e000618. Huerta-Yepez S, Chen PC, Kaur K, Jain Y, Singh T, Esedebe F, Liao YJ, DiBernardo G, Moatamed NA, Mei A, Malarkannan S, Graeber TG, Memarzadeh S, Jewett A. PMID: 40196236; PMCID: PMC11973776.
      View in: PubMed   Mentions:
    3. Defined cellular reprogramming of androgen receptor-active prostate cancer to neuroendocrine prostate cancer. bioRxiv. 2025 Mar 07. Li S, Song K, Sun H, Tao Y, Huang A, Bhatia V, Hanratty B, Patel RA, Long HW, Morrissey C, Haffner MC, Nelson PS, Graeber TG, Lee JK. PMID: 40027790; PMCID: PMC11870442.
      View in: PubMed   Mentions:
    4. The metabolic cofactor Coenzyme A enhances alternative macrophage activation via MyD88-linked signaling. bioRxiv. 2025 Jan 20. Jones AE, Rios A, Ibrahimovic N, Chavez C, Bayley NA, Ball AB, Hsieh WY, Sammarco A, Bianchi AR, Cortez AA, Graeber TG, Hoffmann A, Bensinger SJ, Divakaruni AS. PMID: 38585887; PMCID: PMC10996702.
      View in: PubMed   Mentions:
    5. WITHDRAWN: Single-Cell Heterogeneity of EGFR Pathway Is Linked to Unique Signatures of Drug Response and Malignancy in Patient Derived Glioblastoma Stem Cells. Cancer Res Treat. 2025 01 07. Masterman-Smith MD, Graham NA, Panosyan EH, Mottahedeh J, Samuels ER, Nunez A, Phillips T, Choe M, Cloughesy TF, Lazareff JA, Liau LM, Yong WH, Graeber TG, Kornblum HI, Lang MF, Li Y, Sun J. PMID: 39788641.
      View in: PubMed   Mentions:    Fields:    
    6. PGC-1α drives small cell neuroendocrine cancer progression toward an ASCL1-expressing subtype with increased mitochondrial capacity. Proc Natl Acad Sci U S A. 2024 Dec 03; 121(49):e2416882121. Varuzhanyan G, Chen CC, Freeland J, He T, Tran W, Song K, Wang L, Cheng D, Xu S, Dibernardo GA, Esedebe FN, Bhatia V, Han M, Abt ER, Park JW, Memarzadeh S, Shackelford DB, Lee JK, Graeber TG, Shirihai OS, Witte ON. PMID: 39589879; PMCID: PMC11626175.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    7. Integrated molecular and functional characterization of the intrinsic apoptotic machinery identifies therapeutic vulnerabilities in glioma. Nat Commun. 2024 11 21; 15(1):10089. Fernandez EG, Mai WX, Song K, Bayley NA, Kim J, Zhu H, Pioso M, Young P, Andrasz CL, Cadet D, Liau LM, Li G, Yong WH, Rodriguez FJ, Dixon SJ, Souers AJ, Li JJ, Graeber TG, Cloughesy TF, Nathanson DA. PMID: 39572533; PMCID: PMC11582606.
      View in: PubMed   Mentions:    Fields:    
    8. Genetic Screen in a Preclinical Model of Sarcoma Development Defines Drivers and Therapeutic Vulnerabilities. Clin Cancer Res. 2024 Nov 01; 30(21):4957-4973. Freeland J, Muñoz M, O'Donnell E, Langerman J, Darrow M, Bergonio J, Suarez-Navarro J, Thorpe S, Canter R, Randall RL, Plath K, Carraway KL, Witte ON, Graeber TG, Carr-Ascher JR. PMID: 39177582; PMCID: PMC11530313.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    9. A humanized monoclonal antibody targeting an ectonucleotidase rescues cardiac metabolism and heart function after myocardial infarction. Cell Rep Med. 2024 Nov 19; 5(11):101795. Li S, Tao B, Wan J, Montecino-Rodriguez E, Wang P, Ma F, Sun B, Gu Y, Ramadoss S, Su L, Sun Q, Hoeve JT, Stiles L, Collins J, van Dam RM, Tamboline M, Taschereau R, Shirihai O, Kitchen DB, Pellegrini M, Graeber T, Dorshkind K, Xu S, Deb A. PMID: 39454569; PMCID: PMC11604407.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimalsCells
    10. MITF regulates IDH1, NNT, and a transcriptional program protecting melanoma from reactive oxygen species. Sci Rep. 2024 09 14; 14(1):21527. Roider E, Lakatos AIT, McConnell AM, Wang P, Mueller A, Kawakami A, Tsoi J, Szabolcs BL, Ascsillán AA, Suita Y, Igras V, Lo JA, Hsiao JJ, Lapides R, Pál DMP, Lengyel AS, Navarini A, Okazaki A, Iliopoulos O, Németh I, Graeber TG, Zon L, Giese RW, Kemeny LV, Fisher DE. PMID: 39277608; PMCID: PMC11401838.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimalsCells
    11. Targeting Asparagine Metabolism in Well-Differentiated/Dedifferentiated Liposarcoma. Cancers (Basel). 2024 Aug 30; 16(17). Klingbeil KD, Wilde BR, Graham DS, Lofftus S, McCaw T, Matulionis N, Dry SM, Crompton JG, Eilber FC, Graeber TG, Shackelford DB, Christofk HR, Kadera BE. PMID: 39272889; PMCID: PMC11394161.
      View in: PubMed   Mentions: 1  
    12. Oncogenic pathway signatures predict the risk of progression and recurrence in well-differentiated pancreatic neuroendocrine tumors. J Surg Oncol. 2024 Oct; 130(5):1070-1077. Mederos MA, Court CM, Dipardo BJ, Pisegna JR, Dawson DW, Joe Hines O, Donahue TR, Graeber TG, Girgis MD, Tomlinson JS. PMID: 39155697; PMCID: PMC11654900.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    13. PGC-1α drives small cell neuroendocrine cancer progression towards an ASCL1-expressing subtype with increased mitochondrial capacity. bioRxiv. 2024 Jul 25. Varuzhanyan G, Chen CC, Freeland J, He T, Tran W, Song K, Wang L, Cheng D, Xu S, Dibernardo GA, Esedebe FN, Bhatia V, Han M, Abt ER, Park JW, Memarzadeh S, Shackelford D, Lee JK, Graeber T, Shirihai O, Witte O. PMID: 38645232; PMCID: PMC11030384.
      View in: PubMed   Mentions:
    14. Host immunity contributes to the anti-melanoma activity of BRAF inhibitors. J Clin Invest. 2023 12 15; 133(24). Knight DA, Ngiow SF, Li M, Parmenter T, Mok S, Cass A, Haynes NM, Kinross K, Yagita H, Koya RC, Graeber TG, Ribas A, McArthur GA, Smyth MJ. PMID: 38099495; PMCID: PMC10721136.
      View in: PubMed   Mentions:    Fields:    
    15. Temporal evolution reveals bifurcated lineages in aggressive neuroendocrine small cell prostate cancer trans-differentiation. Cancer Cell. 2023 12 11; 41(12):2066-2082.e9. Chen CC, Tran W, Song K, Sugimoto T, Obusan MB, Wang L, Sheu KM, Cheng D, Ta L, Varuzhanyan G, Huang A, Xu R, Zeng Y, Borujerdpur A, Bayley NA, Noguchi M, Mao Z, Morrissey C, Corey E, Nelson PS, Zhao Y, Huang J, Park JW, Witte ON, Graeber TG. PMID: 37995683; PMCID: PMC10878415.
      View in: PubMed   Mentions: 22     Fields:    Translation:HumansCells
    16. Telomerase reverse transcriptase induces targetable alterations in glutathione and nucleotide biosynthesis in glioblastomas. bioRxiv. 2023 Nov 16. Udutha S, Taglang C, Batsios G, Gillespie AM, Tran M, Ronen SM, Ten Hoeve J, Graeber TG, Viswanath P. PMID: 38014170; PMCID: PMC10680720.
      View in: PubMed   Mentions:
    17. MITF regulates IDH1 and NNT and drives a transcriptional program protecting cutaneous melanoma from reactive oxygen species. bioRxiv. 2023 Nov 14. Roider E, Lakatos AIT, McConnell AM, Wang P, Mueller A, Kawakami A, Tsoi J, Szabolcs BL, Ascsillán AA, Suita Y, Igras V, Lo JA, Hsiao JJ, Lapides R, Pál DMP, Lengyel AS, Navarini A, Okazaki A, Iliopoulos O, Németh I, Graeber TG, Zon L, Giese RW, Kemeny LV, Fisher DE. PMID: 38014031; PMCID: PMC10680652.
      View in: PubMed   Mentions: 1  
    18. A ketogenic diet can mitigate SARS-CoV-2 induced systemic reprogramming and inflammation. Commun Biol. 2023 11 03; 6(1):1115. Palermo A, Li S, Ten Hoeve J, Chellappa A, Morris A, Dillon B, Ma F, Wang Y, Cao E, Shabane B, Acín-Perez R, Petcherski A, Lusis AJ, Hazen S, Shirihai OS, Pellegrini M, Arumugaswami V, Graeber TG, Deb A. PMID: 37923961; PMCID: PMC10624922.
      View in: PubMed   Mentions: 4  Translation:AnimalsCells
    19. Fibroblast Activation Protein Expression in Sarcomas. Sarcoma. 2023; 2023:2480493. Crane JN, Graham DS, Mona CE, Nelson SD, Samiei A, Dawson DW, Dry SM, Masri MG, Crompton JG, Benz MR, Czernin J, Eilber FC, Graeber TG, Calais J, Federman NC. PMID: 37333052; PMCID: PMC10275689.
      View in: PubMed   Mentions: 6  
    20. CDKN2A deletion remodels lipid metabolism to prime glioblastoma for ferroptosis. Cancer Cell. 2023 06 12; 41(6):1048-1060.e9. Minami JK, Morrow D, Bayley NA, Fernandez EG, Salinas JJ, Tse C, Zhu H, Su B, Plawat R, Jones A, Sammarco A, Liau LM, Graeber TG, Williams KJ, Cloughesy TF, Dixon SJ, Bensinger SJ, Nathanson DA. PMID: 37236196; PMCID: PMC10330677.
      View in: PubMed   Mentions: 50     Fields:    Translation:Humans
    21. Tumor heterogeneity in VHL drives metastasis in clear cell renal cell carcinoma. Signal Transduct Target Ther. 2023 04 17; 8(1):155. Hu J, Tan P, Ishihara M, Bayley NA, Schokrpur S, Reynoso JG, Zhang Y, Lim RJ, Dumitras C, Yang L, Dubinett SM, Jat PS, Van Snick J, Huang J, Chin AI, Prins RM, Graeber TG, Xu H, Wu L. PMID: 37069149; PMCID: PMC10110583.
      View in: PubMed   Mentions: 22     Fields:    Translation:Humans
    22. Targeting PEA3 transcription factors to mitigate small cell lung cancer progression. Oncogene. 2023 02; 42(6):434-448. Shia DW, Choi W, Vijayaraj P, Vuong V, Sandlin JM, Lu MM, Aziz A, Marin C, Aros CJ, Sen C, Durra A, Lund AJ, Purkayastha A, Rickabaugh TM, Graeber TG, Gomperts BN. PMID: 36509998; PMCID: PMC9898033.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansCells
    23. Primary and metastatic tumors exhibit systems-level differences in dependence on mitochondrial respiratory function. PLoS Biol. 2022 09; 20(9):e3001753. Bennett NK, Nakaoka HJ, Laurent D, Okimoto RA, Sei Y, Horvai AE, Bivona TG, Ten Hoeve J, Graeber TG, Nakamura K, Nakamura JL. PMID: 36137002; PMCID: PMC9498964.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
    24. Plasticity of Extrachromosomal and Intrachromosomal BRAF Amplifications in Overcoming Targeted Therapy Dosage Challenges. Cancer Discov. 2022 04 01; 12(4):1046-1069. Song K, Minami JK, Huang A, Dehkordi SR, Lomeli SH, Luebeck J, Goodman MH, Moriceau G, Krijgsman O, Dharanipragada P, Ridgley T, Crosson WP, Salazar J, Pazol E, Karin G, Jayaraman R, Balanis NG, Alhani S, Sheu K, Ten Hoeve J, Palermo A, Motika SE, Senaratne TN, Paraiso KH, Hergenrother PJ, Rao PN, Multani AS, Peeper DS, Bafna V, Lo RS, Graeber TG. PMID: 34930786; PMCID: PMC9192483.
      View in: PubMed   Mentions: 32     Fields:    Translation:HumansCells
    25. Cardiomyocytes disrupt pyrimidine biosynthesis in nonmyocytes to regulate heart repair. J Clin Invest. 2022 01 18; 132(2). Li S, Yokota T, Wang P, Ten Hoeve J, Ma F, Le TM, Abt ER, Zhou Y, Wu R, Nanthavongdouangsy M, Rodriguez A, Wang Y, Lin YJ, Muranaka H, Sharpley M, Braddock DT, MacRae VE, Banerjee U, Chiou PY, Seldin M, Huang D, Teitell M, Gertsman I, Jung M, Bensinger SJ, Damoiseaux R, Faull K, Pellegrini M, Lusis AJ, Graeber TG, Radu CG, Deb A. PMID: 34813507; PMCID: PMC8759793.
      View in: PubMed   Mentions: 16     Fields:    Translation:AnimalsCells
    26. Measuring the scientific effectiveness of contact tracing: Evidence from a natural experiment. Proc Natl Acad Sci U S A. 2021 08 17; 118(33). Fetzer T, Graeber T. PMID: 34385318; PMCID: PMC8380024.
      View in: PubMed   Mentions: 30     Fields:    Translation:HumansCellsPHPublic Health
    27. Melanoma dedifferentiation induced by IFN-γ epigenetic remodeling in response to anti-PD-1 therapy. J Clin Invest. 2021 06 15; 131(12). Kim YJ, Sheu KM, Tsoi J, Abril-Rodriguez G, Medina E, Grasso CS, Torrejon DY, Champhekar AS, Litchfield K, Swanton C, Speiser DE, Scumpia PO, Hoffmann A, Graeber TG, Puig-Saus C, Ribas A. PMID: 33914706; PMCID: PMC8203459.
      View in: PubMed   Mentions: 29     Fields:    
    28. Confidence and central tendency in perceptual judgment. Atten Percept Psychophys. 2021 Oct; 83(7):3024-3034. Xiang Y, Graeber T, Enke B, Gershman SJ. PMID: 33890239.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    29. Metabolic reprogramming and epigenetic changes of vital organs in SARS-CoV-2-induced systemic toxicity. JCI Insight. 2021 01 25; 6(2). Li S, Ma F, Yokota T, Garcia G, Palermo A, Wang Y, Farrell C, Wang YC, Wu R, Zhou Z, Pan C, Morselli M, Teitell MA, Ryazantsev S, Fishbein GA, Hoeve JT, Arboleda VA, Bloom J, Dillon B, Pellegrini M, Lusis AJ, Graeber TG, Arumugaswami V, Deb A. PMID: 33284134; PMCID: PMC7934846.
      View in: PubMed   Mentions: 51     Fields:    Translation:HumansAnimalsCells
    30. Intracellular C4BPA Levels Regulate NF-κB-Dependent Apoptosis. iScience. 2020 Oct 23; 23(10):101594. Olcina MM, Kim RK, Balanis NG, Li CG, von Eyben R, Graeber TG, Ricklin D, Stucki M, Giaccia AJ. PMID: 33205012; PMCID: PMC7648136.
      View in: PubMed   Mentions: 5  
    31. Defining the ATPome reveals cross-optimization of metabolic pathways. Nat Commun. 2020 08 28; 11(1):4319. Bennett NK, Nguyen MK, Darch MA, Nakaoka HJ, Cousineau D, Ten Hoeve J, Graeber TG, Schuelke M, Maltepe E, Kampmann M, Mendelsohn BA, Nakamura JL, Nakamura K. PMID: 32859923; PMCID: PMC7455733.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansCells
    32. Thermodynamic energetics underlying genomic instability and whole-genome doubling in cancer. Proc Natl Acad Sci U S A. 2020 08 04; 117(31):18880-18890. Remacle F, Graeber TG, Levine RD. PMID: 32694208; PMCID: PMC7414060.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    33. Integrin α6 mediates the drug resistance of acute lymphoblastic B-cell leukemia. Blood. 2020 07 09; 136(2):210-223. Gang EJ, Kim HN, Hsieh YT, Ruan Y, Ogana HA, Lee S, Pham J, Geng H, Park E, Klemm L, Willman CL, Carroll WL, Mittelman SD, Orgel E, Oberley MJ, Parekh C, Abdel-Azim H, Bhojwani D, Wayne AS, De Arcangelis A, Georges-Labouesse E, Wayner E, Bonig H, Minasyan A, Ten Hoeve J, Graeber TG, Müschen M, Heisterkamp N, Kim YM. PMID: 32219444; PMCID: PMC7357190.
      View in: PubMed   Mentions: 28     Fields:    Translation:HumansAnimals
    34. Somatic copy number profiling from hepatocellular carcinoma circulating tumor cells. NPJ Precis Oncol. 2020; 4:16. Court CM, Hou S, Liu L, Winograd P, DiPardo BJ, Liu SX, Chen PJ, Zhu Y, Smalley M, Zhang R, Sadeghi S, Finn RS, Kaldas FM, Busuttil RW, Zhou XJ, Tseng HR, Tomlinson JS, Graeber TG, Agopian VG. PMID: 32637655; PMCID: PMC7331695.
      View in: PubMed   Mentions: 8  
    35. Delayed negative effects of prosocial spending on happiness. Proc Natl Acad Sci U S A. 2020 03 24; 117(12):6463-6468. Falk A, Graeber T. PMID: 32152104; PMCID: PMC7161742.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    36. A genetically defined disease model reveals that urothelial cells can initiate divergent bladder cancer phenotypes. Proc Natl Acad Sci U S A. 2020 01 07; 117(1):563-572. Wang L, Smith BA, Balanis NG, Tsai BL, Nguyen K, Cheng MW, Obusan MB, Esedebe FN, Patel SJ, Zhang H, Clark PM, Sisk AE, Said JW, Huang J, Graeber TG, Witte ON, Chin AI, Park JW. PMID: 31871155; PMCID: PMC6955337.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansAnimalsCells
    37. Modeling Progressive Fibrosis with Pluripotent Stem Cells Identifies an Anti-fibrotic Small Molecule. Cell Rep. 2019 12 10; 29(11):3488-3505.e9. Vijayaraj P, Minasyan A, Durra A, Karumbayaram S, Mehrabi M, Aros CJ, Ahadome SD, Shia DW, Chung K, Sandlin JM, Darmawan KF, Bhatt KV, Manze CC, Paul MK, Wilkinson DC, Yan W, Clark AT, Rickabaugh TM, Wallace WD, Graeber TG, Damoiseaux R, Gomperts BN. PMID: 31825831; PMCID: PMC6927560.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansAnimalsCells
    38. Interferon Receptor Signaling Pathways Regulating PD-L1 and PD-L2 Expression. Cell Rep. 2019 Dec 10; 29(11):3766. Garcia-Diaz A, Shin DS, Moreno BH, Saco J, Escuin-Ordinas H, Rodriguez GA, Zaretsky JM, Sun L, Hugo W, Wang X, Parisi G, Saus CP, Torrejon DY, Graeber TG, Comin-Anduix B, Hu-Lieskovan S, Damoiseaux R, Lo RS, Ribas A. PMID: 31825850.
      View in: PubMed   Mentions: 59     Fields:    
    39. Global alteration of T-lymphocyte metabolism by PD-L1 checkpoint involves a block of de novo nucleoside phosphate synthesis. Cell Discov. 2019; 5:62. Palaskas NJ, Garcia JD, Shirazi R, Shin DS, Puig-Saus C, Braas D, Ribas A, Graeber TG. PMID: 31798961; PMCID: PMC6877514.
      View in: PubMed   Mentions: 16  
    40. Hyperoxia but not AOX expression mitigates pathological cardiac remodeling in a mouse model of inflammatory cardiomyopathy. Sci Rep. 2019 09 04; 9(1):12741. Dhandapani PK, Begines-Moreno IM, Brea-Calvo G, Gärtner U, Graeber TG, Javier Sanchez G, Morty RE, Schönig K, Hoeve JT, Wietelmann A, Braun T, Jacobs HT, Szibor M. PMID: 31484989; PMCID: PMC6726756.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansAnimalsCells
    41. A linear mixed model approach to gene expression-tumor aneuploidy association studies. Sci Rep. 2019 08 16; 9(1):11944. Yao DW, Balanis NG, Eskin E, Graeber TG. PMID: 31420589; PMCID: PMC6697733.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    42. Pan-cancer Convergence to a Small-Cell Neuroendocrine Phenotype that Shares Susceptibilities with Hematological Malignancies. Cancer Cell. 2019 07 08; 36(1):17-34.e7. Balanis NG, Sheu KM, Esedebe FN, Patel SJ, Smith BA, Park JW, Alhani S, Gomperts BN, Huang J, Witte ON, Graeber TG. PMID: 31287989; PMCID: PMC6703903.
      View in: PubMed   Mentions: 74     Fields:    Translation:HumansCells
    43. Ampk regulates IgD expression but not energy stress with B cell activation. Sci Rep. 2019 06 03; 9(1):8176. Waters LR, Ahsan FM, Ten Hoeve J, Hong JS, Kim DNH, Minasyan A, Braas D, Graeber TG, Zangle TA, Teitell MA. PMID: 31160601; PMCID: PMC6546716.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansAnimalsCells
    44. Multi-omics of the gut microbial ecosystem in inflammatory bowel diseases. Nature. 2019 05; 569(7758):655-662. Lloyd-Price J, Arze C, Ananthakrishnan AN, Schirmer M, Avila-Pacheco J, Poon TW, Andrews E, Ajami NJ, Bonham KS, Brislawn CJ, Casero D, Courtney H, Gonzalez A, Graeber TG, Hall AB, Lake K, Landers CJ, Mallick H, Plichta DR, Prasad M, Rahnavard G, Sauk J, Shungin D, Vázquez-Baeza Y, White RA, IBDMDB Investigators, Braun J, Denson LA, Jansson JK, Knight R, Kugathasan S, McGovern DPB, Petrosino JF, Stappenbeck TS, Winter HS, Clish CB, Franzosa EA, Vlamakis H, Xavier RJ, Huttenhower C. PMID: 31142855; PMCID: PMC6650278.
      View in: PubMed   Mentions: 1147     Fields:    Translation:HumansAnimalsCells
    45. Interleukin 32 expression in human melanoma. J Transl Med. 2019 04 05; 17(1):113. Paz H, Tsoi J, Kalbasi A, Grasso CS, McBride WH, Schaue D, Butterfield LH, Maurer DM, Ribas A, Graeber TG, Economou JS. PMID: 30953519; PMCID: PMC6449995.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansCells
    46. Mutations in an Innate Immunity Pathway Are Associated with Poor Overall Survival Outcomes and Hypoxic Signaling in Cancer. Cell Rep. 2018 12 26; 25(13):3721-3732.e6. Olcina MM, Balanis NG, Kim RK, Aksoy BA, Kodysh J, Thompson MJ, Hammerbacher J, Graeber TG, Giaccia AJ. PMID: 30590044; PMCID: PMC6405289.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansAnimalsCells
    47. Reprogramming normal human epithelial tissues to a common, lethal neuroendocrine cancer lineage. Science. 2018 10 05; 362(6410):91-95. Park JW, Lee JK, Sheu KM, Wang L, Balanis NG, Nguyen K, Smith BA, Cheng C, Tsai BL, Cheng D, Huang J, Kurdistani SK, Graeber TG, Witte ON. PMID: 30287662; PMCID: PMC6414229.
      View in: PubMed   Mentions: 155     Fields:    Translation:HumansCells
    48. A Human Adult Stem Cell Signature Marks Aggressive Variants across Epithelial Cancers. Cell Rep. 2018 09 18; 24(12):3353-3366.e5. Smith BA, Balanis NG, Nanjundiah A, Sheu KM, Tsai BL, Zhang Q, Park JW, Thompson M, Huang J, Witte ON, Graeber TG. PMID: 30232014; PMCID: PMC6382070.
      View in: PubMed   Mentions: 58     Fields:    Translation:AnimalsCells
    49. Phosphopeptide Enrichment Coupled with Label-free Quantitative Mass Spectrometry to Investigate the Phosphoproteome in Prostate Cancer. J Vis Exp. 2018 08 02; (138). Cheng LC, Li Z, Graeber TG, Graham NA, Drake JM. PMID: 30124664; PMCID: PMC6126612.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    50. A precision therapeutic strategy for hexokinase 1-null, hexokinase 2-positive cancers. Cancer Metab. 2018; 6:7. Xu S, Catapang A, Braas D, Stiles L, Doh HM, Lee JT, Graeber TG, Damoiseaux R, Shirihai O, Herschman HR. PMID: 29988332; PMCID: PMC6022704.
      View in: PubMed   Mentions: 16  
    51. Hexokinase 2 is targetable for HK1 negative, HK2 positive tumors from a wide variety of tissues of origin. J Nucl Med. 2018 Jun 07. Xu S, Catapang A, Doh HM, Bayley NA, Lee JT, Braas D, Graeber TG, Herschman HR. PMID: 29880505; PMCID: PMC8833855.
      View in: PubMed   Mentions: 10     Fields:    
    52. Author Correction: Metabolic gatekeeper function of B-lymphoid transcription factors. Nature. 2018 06; 558(7711):E5. Chan LN, Chen Z, Braas D, Lee JW, Xiao G, Geng H, Cosgun KN, Hurtz C, Shojaee S, Cazzaniga V, Schjerven H, Ernst T, Hochhaus A, Kornblau SM, Konopleva M, Pufall MA, Cazzaniga G, Liu GJ, Milne TA, Koeffler HP, Ross TS, Sánchez-García I, Borkhardt A, Yamamoto KR, Dickins RA, Graeber TG, Müschen M. PMID: 29849140.
      View in: PubMed   Mentions:    Fields:    
    53. Making Mistakes Empowers Cancer Cells. Trends Cancer. 2018 07; 4(7):461-463. Balanis NG, Graeber TG. PMID: 29937042.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    54. The GSK3 Signaling Axis Regulates Adaptive Glutamine Metabolism in Lung Squamous Cell Carcinoma. Cancer Cell. 2018 05 14; 33(5):905-921.e5. Momcilovic M, Bailey ST, Lee JT, Fishbein MC, Braas D, Go J, Graeber TG, Parlati F, Demo S, Li R, Walser TC, Gricowski M, Shuman R, Ibarra J, Fridman D, Phelps ME, Badran K, St John M, Bernthal NM, Federman N, Yanagawa J, Dubinett SM, Sadeghi S, Christofk HR, Shackelford DB. PMID: 29763624; PMCID: PMC6451645.
      View in: PubMed   Mentions: 90     Fields:    Translation:HumansAnimalsCells
    55. Systemic surfaceome profiling identifies target antigens for immune-based therapy in subtypes of advanced prostate cancer. Proc Natl Acad Sci U S A. 2018 05 08; 115(19):E4473-E4482. Lee JK, Bangayan NJ, Chai T, Smith BA, Pariva TE, Yun S, Vashisht A, Zhang Q, Park JW, Corey E, Huang J, Graeber TG, Wohlschlegel J, Witte ON. PMID: 29686080; PMCID: PMC5949005.
      View in: PubMed   Mentions: 76     Fields:    Translation:HumansCells
    56. Metabolic characterization of isocitrate dehydrogenase (IDH) mutant and IDH wildtype gliomaspheres uncovers cell type-specific vulnerabilities. Cancer Metab. 2018; 6:4. Garrett M, Sperry J, Braas D, Yan W, Le TM, Mottahedeh J, Ludwig K, Eskin A, Qin Y, Levy R, Breunig JJ, Pajonk F, Graeber TG, Radu CG, Christofk H, Prins RM, Lai A, Liau LM, Coppola G, Kornblum HI. PMID: 29692895; PMCID: PMC5905129.
      View in: PubMed   Mentions: 39  
    57. Multi-stage Differentiation Defines Melanoma Subtypes with Differential Vulnerability to Drug-Induced Iron-Dependent Oxidative Stress. Cancer Cell. 2018 05 14; 33(5):890-904.e5. Tsoi J, Robert L, Paraiso K, Galvan C, Sheu KM, Lay J, Wong DJL, Atefi M, Shirazi R, Wang X, Braas D, Grasso CS, Palaskas N, Ribas A, Graeber TG. PMID: 29657129; PMCID: PMC5953834.
      View in: PubMed   Mentions: 410     Fields:    Translation:HumansCells
    58. B-Cell-Specific Diversion of Glucose Carbon Utilization Reveals a Unique Vulnerability in B Cell Malignancies. Cell. 2018 04 05; 173(2):470-484.e18. Xiao G, Chan LN, Klemm L, Braas D, Chen Z, Geng H, Zhang QC, Aghajanirefah A, Cosgun KN, Sadras T, Lee J, Mirzapoiazova T, Salgia R, Ernst T, Hochhaus A, Jumaa H, Jiang X, Weinstock DM, Graeber TG, Müschen M. PMID: 29551267; PMCID: PMC6284818.
      View in: PubMed   Mentions: 70     Fields:    Translation:HumansAnimalsCells
    59. Circulating Tumor Cells Predict Occult Metastatic Disease and Prognosis in Pancreatic Cancer. Ann Surg Oncol. 2018 Apr; 25(4):1000-1008. Court CM, Ankeny JS, Sho S, Winograd P, Hou S, Song M, Wainberg ZA, Girgis MD, Graeber TG, Agopian VG, Tseng HR, Tomlinson JS. PMID: 29442211; PMCID: PMC5896564.
      View in: PubMed   Mentions: 52     Fields:    Translation:HumansCells
    60. Single-cell analysis resolves the cell state transition and signaling dynamics associated with melanoma drug-induced resistance. Proc Natl Acad Sci U S A. 2017 12 26; 114(52):13679-13684. Su Y, Wei W, Robert L, Xue M, Tsoi J, Garcia-Diaz A, Homet Moreno B, Kim J, Ng RH, Lee JW, Koya RC, Comin-Anduix B, Graeber TG, Ribas A, Heath JR. PMID: 29229836; PMCID: PMC5748184.
      View in: PubMed   Mentions: 120     Fields:    Translation:HumansCells
    61. Lactate dehydrogenase activity drives hair follicle stem cell activation. Nat Cell Biol. 2017 Sep; 19(9):1017-1026. Flores A, Schell J, Krall AS, Jelinek D, Miranda M, Grigorian M, Braas D, White AC, Zhou JL, Graham NA, Graeber T, Seth P, Evseenko D, Coller HA, Rutter J, Christofk HR, Lowry WE. PMID: 28812580; PMCID: PMC5657543.
      View in: PubMed   Mentions: 126     Fields:    Translation:AnimalsCells
    62. Precision oncology using a limited number of cells: optimization of whole genome amplification products for sequencing applications. BMC Cancer. 2017 Jul 01; 17(1):457. Sho S, Court CM, Winograd P, Lee S, Hou S, Graeber TG, Tseng HR, Tomlinson JS. PMID: 28666423; PMCID: PMC5493892.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansCells
    63. Ibrutinib Unmasks Critical Role of Bruton Tyrosine Kinase in Primary CNS Lymphoma. Cancer Discov. 2017 09; 7(9):1018-1029. Grommes C, Pastore A, Palaskas N, Tang SS, Campos C, Schartz D, Codega P, Nichol D, Clark O, Hsieh WY, Rohle D, Rosenblum M, Viale A, Tabar VS, Brennan CW, Gavrilovic IT, Kaley TJ, Nolan CP, Omuro A, Pentsova E, Thomas AA, Tsyvkin E, Noy A, Palomba ML, Hamlin P, Sauter CS, Moskowitz CH, Wolfe J, Dogan A, Won M, Glass J, Peak S, Lallana EC, Hatzoglou V, Reiner AS, Gutin PH, Huse JT, Panageas KS, Graeber TG, Schultz N, DeAngelis LM, Mellinghoff IK. PMID: 28619981; PMCID: PMC5581705.
      View in: PubMed   Mentions: 159     Fields:    Translation:HumansCTClinical Trials
    64. Interferon Receptor Signaling Pathways Regulating PD-L1 and PD-L2 Expression. Cell Rep. 2017 05 09; 19(6):1189-1201. Garcia-Diaz A, Shin DS, Moreno BH, Saco J, Escuin-Ordinas H, Rodriguez GA, Zaretsky JM, Sun L, Hugo W, Wang X, Parisi G, Saus CP, Torrejon DY, Graeber TG, Comin-Anduix B, Hu-Lieskovan S, Damoiseaux R, Lo RS, Ribas A. PMID: 28494868; PMCID: PMC6420824.
      View in: PubMed   Mentions: 913     Fields:    Translation:HumansCells
    65. Recurrent patterns of DNA copy number alterations in tumors reflect metabolic selection pressures. Mol Syst Biol. 2017 02 15; 13(2):914. Graham NA, Minasyan A, Lomova A, Cass A, Balanis NG, Friedman M, Chan S, Zhao S, Delgado A, Go J, Beck L, Hurtz C, Ng C, Qiao R, Ten Hoeve J, Palaskas N, Wu H, Müschen M, Multani AS, Port E, Larson SM, Schultz N, Braas D, Christofk HR, Mellinghoff IK, Graeber TG. PMID: 28202506; PMCID: PMC5327725.
      View in: PubMed   Mentions: 37     Fields:    Translation:HumansCells
    66. Metabolic gatekeeper function of B-lymphoid transcription factors. Nature. 2017 02 23; 542(7642):479-483. Chan LN, Chen Z, Braas D, Lee JW, Xiao G, Geng H, Cosgun KN, Hurtz C, Shojaee S, Cazzaniga V, Schjerven H, Ernst T, Hochhaus A, Kornblau SM, Konopleva M, Pufall MA, Cazzaniga G, Liu GJ, Milne TA, Koeffler HP, Ross TS, Sánchez-García I, Borkhardt A, Yamamoto KR, Dickins RA, Graeber TG, Müschen M. PMID: 28192788; PMCID: PMC5621518.
      View in: PubMed   Mentions: 126     Fields:    
    67. Targeted Inhibition of EGFR and Glutaminase Induces Metabolic Crisis in EGFR Mutant Lung Cancer. Cell Rep. 2017 01 17; 18(3):601-610. Momcilovic M, Bailey ST, Lee JT, Fishbein MC, Magyar C, Braas D, Graeber T, Jackson NJ, Czernin J, Emberley E, Gross M, Janes J, Mackinnon A, Pan A, Rodriguez M, Works M, Zhang W, Parlati F, Demo S, Garon E, Krysan K, Walser TC, Dubinett SM, Sadeghi S, Christofk HR, Shackelford DB. PMID: 28099841; PMCID: PMC5260616.
      View in: PubMed   Mentions: 81     Fields:    Translation:HumansAnimalsCells
    68. Primary Resistance to PD-1 Blockade Mediated by JAK1/2 Mutations. Cancer Discov. 2017 02; 7(2):188-201. Shin DS, Zaretsky JM, Escuin-Ordinas H, Garcia-Diaz A, Hu-Lieskovan S, Kalbasi A, Grasso CS, Hugo W, Sandoval S, Torrejon DY, Palaskas N, Rodriguez GA, Parisi G, Azhdam A, Chmielowski B, Cherry G, Seja E, Berent-Maoz B, Shintaku IP, Le DT, Pardoll DM, Diaz LA, Tumeh PC, Graeber TG, Lo RS, Comin-Anduix B, Ribas A. PMID: 27903500; PMCID: PMC5296316.
      View in: PubMed   Mentions: 649     Fields:    Translation:HumansCells
    69. JUN dependency in distinct early and late BRAF inhibition adaptation states of melanoma. Cell Discov. 2016; 2:16028. Titz B, Lomova A, Le A, Hugo W, Kong X, Ten Hoeve J, Friedman M, Shi H, Moriceau G, Song C, Hong A, Atefi M, Li R, Komisopoulou E, Ribas A, Lo RS, Graeber TG. PMID: 27648299; PMCID: PMC5012007.
      View in: PubMed   Mentions: 31  
    70. Response to Programmed Cell Death-1 Blockade in a Murine Melanoma Syngeneic Model Requires Costimulation, CD4, and CD8 T Cells. Cancer Immunol Res. 2016 10; 4(10):845-857. Homet Moreno B, Zaretsky JM, Garcia-Diaz A, Tsoi J, Parisi G, Robert L, Meeth K, Ndoye A, Bosenberg M, Weeraratna AT, Graeber TG, Comin-Anduix B, Hu-Lieskovan S, Ribas A. PMID: 27589875; PMCID: PMC5050168.
      View in: PubMed   Mentions: 87     Fields:    Translation:AnimalsCells
    71. Phosphoproteome Integration Reveals Patient-Specific Networks in Prostate Cancer. Cell. 2016 Aug 11; 166(4):1041-1054. Drake JM, Paull EO, Graham NA, Lee JK, Smith BA, Titz B, Stoyanova T, Faltermeier CM, Uzunangelov V, Carlin DE, Fleming DT, Wong CK, Newton Y, Sudha S, Vashisht AA, Huang J, Wohlschlegel JA, Graeber TG, Witte ON, Stuart JM. PMID: 27499020; PMCID: PMC4985183.
      View in: PubMed   Mentions: 111     Fields:    Translation:HumansCells
    72. α-Ketoglutarate Accelerates the Initial Differentiation of Primed Human Pluripotent Stem Cells. Cell Metab. 2016 09 13; 24(3):485-493. TeSlaa T, Chaikovsky AC, Lipchina I, Escobar SL, Hochedlinger K, Huang J, Graeber TG, Braas D, Teitell MA. PMID: 27476976; PMCID: PMC5023506.
      View in: PubMed   Mentions: 139     Fields:    Translation:HumansCells
    73. Mutations Associated with Acquired Resistance to PD-1 Blockade in Melanoma. N Engl J Med. 2016 Sep 01; 375(9):819-29. Zaretsky JM, Garcia-Diaz A, Shin DS, Escuin-Ordinas H, Hugo W, Hu-Lieskovan S, Torrejon DY, Abril-Rodriguez G, Sandoval S, Barthly L, Saco J, Homet Moreno B, Mezzadra R, Chmielowski B, Ruchalski K, Shintaku IP, Sanchez PJ, Puig-Saus C, Cherry G, Seja E, Kong X, Pang J, Berent-Maoz B, Comin-Anduix B, Graeber TG, Tumeh PC, Schumacher TN, Lo RS, Ribas A. PMID: 27433843; PMCID: PMC5007206.
      View in: PubMed   Mentions: 1512     Fields:    Translation:HumansCells
    74. Reality of Single Circulating Tumor Cell Sequencing for Molecular Diagnostics in Pancreatic Cancer. J Mol Diagn. 2016 09; 18(5):688-696. Court CM, Ankeny JS, Sho S, Hou S, Li Q, Hsieh C, Song M, Liao X, Rochefort MM, Wainberg ZA, Graeber TG, Tseng HR, Tomlinson JS. PMID: 27375074; PMCID: PMC5397706.
      View in: PubMed   Mentions: 24     Fields:    Translation:HumansCells
    75. CRAF R391W is a melanoma driver oncogene. Sci Rep. 2016 06 08; 6:27454. Atefi M, Titz B, Tsoi J, Avramis E, Le A, Ng C, Lomova A, Lassen A, Friedman M, Chmielowski B, Ribas A, Graeber TG. PMID: 27273450; PMCID: PMC4897636.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansAnimalsCells
    76. Microgeographic Proteomic Networks of the Human Colonic Mucosa and Their Association With Inflammatory Bowel Disease. Cell Mol Gastroenterol Hepatol. 2016 Sep; 2(5):567-583. Li X, LeBlanc J, Elashoff D, McHardy I, Tong M, Roth B, Ippoliti A, Barron G, McGovern D, McDonald K, Newberry R, Graeber T, Horvath S, Goodglick L, Braun J. PMID: 28174738; PMCID: PMC5042708.
      View in: PubMed   Mentions: 21     Fields:    
    77. Mitochondrial Transfer by Photothermal Nanoblade Restores Metabolite Profile in Mammalian Cells. Cell Metab. 2016 05 10; 23(5):921-9. Wu TH, Sagullo E, Case D, Zheng X, Li Y, Hong JS, TeSlaa T, Patananan AN, McCaffery JM, Niazi K, Braas D, Koehler CM, Graeber TG, Chiou PY, Teitell MA. PMID: 27166949; PMCID: PMC5062745.
      View in: PubMed   Mentions: 51     Fields:    Translation:HumansAnimalsCells
    78. Multiplexed immunofluorescence delineates proteomic cancer cell states associated with metabolism. JCI Insight. 2016 May 05; 1(6). Sood A, Miller AM, Brogi E, Sui Y, Armenia J, McDonough E, Santamaria-Pang A, Carlin S, Stamper A, Campos C, Pang Z, Li Q, Port E, Graeber TG, Schultz N, Ginty F, Larson SM, Mellinghoff IK. PMID: 27182557; PMCID: PMC4863708.
      View in: PubMed   Mentions: 26     Fields:    
    79. Asparagine promotes cancer cell proliferation through use as an amino acid exchange factor. Nat Commun. 2016 Apr 29; 7:11457. Krall AS, Xu S, Graeber TG, Braas D, Christofk HR. PMID: 27126896; PMCID: PMC4855534.
      View in: PubMed   Mentions: 251     Fields:    Translation:HumansCells
    80. PTEN opposes negative selection and enables oncogenic transformation of pre-B cells. Nat Med. 2016 Apr; 22(4):379-87. Shojaee S, Chan LN, Buchner M, Cazzaniga V, Cosgun KN, Geng H, Qiu YH, von Minden MD, Ernst T, Hochhaus A, Cazzaniga G, Melnick A, Kornblau SM, Graeber TG, Wu H, Jumaa H, Müschen M. PMID: 26974310; PMCID: PMC5178869.
      View in: PubMed   Mentions: 60     Fields:    Translation:HumansAnimalsCells
    81. Corrigendum: Signalling thresholds and negative B-cell selection in acute lymphoblastic leukaemia. Nature. 2016 06 02; 534(7605):138. Chen Z, Shojaee S, Buchner M, Geng H, Lee JW, Klemm L, Titz B, Graeber TG, Park E, Tan YX, Satterthwaite A, Paietta E, Hunger SP, Willman CL, Melnick A, Loh ML, Jung JU, Coligan JE, Bolland S, Mak TW, Limnander A, Jumaa H, Reth M, Weiss A, Lowell CA, Müschen M. PMID: 26958840.
      View in: PubMed   Mentions:    Fields:    
    82. MCT1 Modulates Cancer Cell Pyruvate Export and Growth of Tumors that Co-express MCT1 and MCT4. Cell Rep. 2016 Feb 23; 14(7):1590-1601. Hong CS, Graham NA, Gu W, Espindola Camacho C, Mah V, Maresh EL, Alavi M, Bagryanova L, Krotee PAL, Gardner BK, Behbahan IS, Horvath S, Chia D, Mellinghoff IK, Hurvitz SA, Dubinett SM, Critchlow SE, Kurdistani SK, Goodglick L, Braas D, Graeber TG, Christofk HR. PMID: 26876179; PMCID: PMC4816454.
      View in: PubMed   Mentions: 113     Fields:    Translation:HumansAnimalsCells
    83. The Role of CD44 in Glucose Metabolism in Prostatic Small Cell Neuroendocrine Carcinoma. Mol Cancer Res. 2016 Apr; 14(4):344-53. Li W, Cohen A, Sun Y, Squires J, Braas D, Graeber TG, Du L, Li G, Li Z, Xu X, Chen X, Huang J. PMID: 26832214; PMCID: PMC4834240.
      View in: PubMed   Mentions: 26     Fields:    Translation:HumansCells
    84. Host immunity contributes to the anti-melanoma activity of BRAF inhibitors. J Clin Invest. 2016 Jan; 126(1):402-3. Knight DA, Ngiow SF, Li M, Parmenter T, Mok S, Cass A, Haynes NM, Kinross K, Yagita H, Koya RC, Graeber TG, Ribas A, McArthur GA, Smyth MJ. PMID: 26595810; PMCID: PMC4701538.
      View in: PubMed   Mentions: 9     Fields:    
    85. MYC-induced reprogramming of glutamine catabolism supports optimal virus replication. Nat Commun. 2015 Nov 12; 6:8873. Thai M, Thaker SK, Feng J, Du Y, Hu H, Ting Wu T, Graeber TG, Braas D, Christofk HR. PMID: 26561297; PMCID: PMC4660206.
      View in: PubMed   Mentions: 74     Fields:    Translation:HumansCells
    86. 2-Hydroxyglutarate Inhibits ATP Synthase and mTOR Signaling. Cell Metab. 2015 Sep 01; 22(3):508-15. Fu X, Chin RM, Vergnes L, Hwang H, Deng G, Xing Y, Pai MY, Li S, Ta L, Fazlollahi F, Chen C, Prins RM, Teitell MA, Nathanson DA, Lai A, Faull KF, Jiang M, Clarke SG, Cloughesy TF, Graeber TG, Braas D, Christofk HR, Jung ME, Reue K, Huang J. PMID: 26190651; PMCID: PMC4663076.
      View in: PubMed   Mentions: 125     Fields:    Translation:HumansAnimalsCells
    87. DNA-PKcs-Mediated Transcriptional Regulation Drives Prostate Cancer Progression and Metastasis. Cancer Cell. 2015 Jul 13; 28(1):97-113. Goodwin JF, Kothari V, Drake JM, Zhao S, Dylgjeri E, Dean JL, Schiewer MJ, McNair C, Jones JK, Aytes A, Magee MS, Snook AE, Zhu Z, Den RB, Birbe RC, Gomella LG, Graham NA, Vashisht AA, Wohlschlegel JA, Graeber TG, Karnes RJ, Takhar M, Davicioni E, Tomlins SA, Abate-Shen C, Sharifi N, Witte ON, Feng FY, Knudsen KE. PMID: 26175416; PMCID: PMC4531387.
      View in: PubMed   Mentions: 95     Fields:    Translation:HumansAnimalsCells
    88. Erratum to: Antitumor activity of the ERK inhibitor SCH722984 against BRAF mutant, NRAS mutant and wild-type melanoma. Mol Cancer. 2015 Jul 02; 14:128. Wong DJ, Robert L, Atefi MS, Lassen A, Avarappatt G, Cerniglia M, Avramis E, Tsoi J, Foulad D, Graeber TG, Comin-Anduix B, Samatar A, Lo RS, Ribas A. PMID: 26134498; PMCID: PMC4488977.
      View in: PubMed   Mentions: 3     Fields:    
    89. Tyrosine phosphorylation of RAS by ABL allosterically enhances effector binding. FASEB J. 2015 Sep; 29(9):3750-61. Ting PY, Johnson CW, Fang C, Cao X, Graeber TG, Mattos C, Colicelli J. PMID: 25999467; PMCID: PMC4550377.
      View in: PubMed   Mentions: 25     Fields:    Translation:HumansAnimalsCells
    90. Inhibition of colony stimulating factor-1 receptor improves antitumor efficacy of BRAF inhibition. BMC Cancer. 2015 May 05; 15:356. Mok S, Tsoi J, Koya RC, Hu-Lieskovan S, West BL, Bollag G, Graeber TG, Ribas A. PMID: 25939769; PMCID: PMC4432503.
      View in: PubMed   Mentions: 33     Fields:    Translation:AnimalsCells
    91. Identification of small molecules that disrupt signaling between ABL and its positive regulator RIN1. PLoS One. 2015; 10(3):e0121833. Ting PY, Damoiseaux R, Titz B, Bradley KA, Graeber TG, Fernández-Vega V, Bannister TD, Chase P, Nair R, Scampavia L, Hodder P, Spicer TP, Colicelli J. PMID: 25811598; PMCID: PMC4374917.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    92. Signalling thresholds and negative B-cell selection in acute lymphoblastic leukaemia. Nature. 2015 May 21; 521(7552):357-61. Chen Z, Shojaee S, Buchner M, Geng H, Lee JW, Klemm L, Titz B, Graeber TG, Park E, Tan YX, Satterthwaite A, Paietta E, Hunger SP, Willman CL, Melnick A, Loh ML, Jung JU, Coligan JE, Bolland S, Mak TW, Limnander A, Jumaa H, Reth M, Weiss A, Lowell CA, Müschen M. PMID: 25799995; PMCID: PMC4441554.
      View in: PubMed   Mentions: 72     Fields:    
    93. Improved antitumor activity of immunotherapy with BRAF and MEK inhibitors in BRAF(V600E) melanoma. Sci Transl Med. 2015 Mar 18; 7(279):279ra41. Hu-Lieskovan S, Mok S, Homet Moreno B, Tsoi J, Robert L, Goedert L, Pinheiro EM, Koya RC, Graeber TG, Comin-Anduix B, Ribas A. PMID: 25787767; PMCID: PMC4765379.
      View in: PubMed   Mentions: 283     Fields:    Translation:HumansAnimalsCells
    94. Combination of pan-RAF and MEK inhibitors in NRAS mutant melanoma. Mol Cancer. 2015 Feb 03; 14:27. Atefi M, Titz B, Avramis E, Ng C, Wong DJ, Lassen A, Cerniglia M, Escuin-Ordinas H, Foulad D, Comin-Anduix B, Graeber TG, Ribas A. PMID: 25645078; PMCID: PMC4320814.
      View in: PubMed   Mentions: 32     Fields:    Translation:HumansCells
    95. MITF drives endolysosomal biogenesis and potentiates Wnt signaling in melanoma cells. Proc Natl Acad Sci U S A. 2015 Feb 03; 112(5):E420-9. Ploper D, Taelman VF, Robert L, Perez BS, Titz B, Chen HW, Graeber TG, von Euw E, Ribas A, De Robertis EM. PMID: 25605940; PMCID: PMC4321275.
      View in: PubMed   Mentions: 127     Fields:    Translation:HumansCells
    96. Low MITF/AXL ratio predicts early resistance to multiple targeted drugs in melanoma. Nat Commun. 2014 Dec 15; 5:5712. Müller J, Krijgsman O, Tsoi J, Robert L, Hugo W, Song C, Kong X, Possik PA, Cornelissen-Steijger PD, Geukes Foppen MH, Kemper K, Goding CR, McDermott U, Blank C, Haanen J, Graeber TG, Ribas A, Lo RS, Peeper DS. PMID: 25502142; PMCID: PMC4428333.
      View in: PubMed   Mentions: 304     Fields:    Translation:HumansAnimalsCells
    97. Antitumor activity of the ERK inhibitor SCH772984 [corrected] against BRAF mutant, NRAS mutant and wild-type melanoma. Mol Cancer. 2014 Aug 20; 13:194. Wong DJ, Robert L, Atefi MS, Lassen A, Avarappatt G, Cerniglia M, Avramis E, Tsoi J, Foulad D, Graeber TG, Comin-Anduix B, Samatar A, Lo RS, Ribas A. PMID: 25142146; PMCID: PMC4155088.
      View in: PubMed   Mentions: 48     Fields:    Translation:HumansCells
    98. Comparison of molecular signatures from multiple skin diseases identifies mechanisms of immunopathogenesis. J Invest Dermatol. 2015 Jan; 135(1):151-159. Inkeles MS, Scumpia PO, Swindell WR, Lopez D, Teles RMB, Graeber TG, Meller S, Homey B, Elder JT, Gilliet M, Modlin RL, Pellegrini M. PMID: 25111617; PMCID: PMC4268388.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansCells
    99. Phosphoproteomic profiling reveals IL6-mediated paracrine signaling within the Ewing sarcoma family of tumors. Mol Cancer Res. 2014 Dec; 12(12):1740-54. Anderson JL, Titz B, Akiyama R, Komisopoulou E, Park A, Tap WD, Graeber TG, Denny CT. PMID: 25092916.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansCells
    100. Complexity of metastasis-associated SDF-1 ligand signaling in breast cancer stem cells. Proc Natl Acad Sci U S A. 2014 May 27; 111(21):7503-4. Graham NA, Graeber TG. PMID: 24828528; PMCID: PMC4040584.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansAnimalsCells
    101. Effects of MAPK and PI3K pathways on PD-L1 expression in melanoma. Clin Cancer Res. 2014 Jul 01; 20(13):3446-57. Atefi M, Avramis E, Lassen A, Wong DJ, Robert L, Foulad D, Cerniglia M, Titz B, Chodon T, Graeber TG, Comin-Anduix B, Ribas A. PMID: 24812408; PMCID: PMC4079734.
      View in: PubMed   Mentions: 194     Fields:    Translation:HumansCells
    102. Reprograming of gut microbiome energy metabolism by the FUT2 Crohn's disease risk polymorphism. ISME J. 2014 Nov; 8(11):2193-206. Tong M, McHardy I, Ruegger P, Goudarzi M, Kashyap PC, Haritunians T, Li X, Graeber TG, Schwager E, Huttenhower C, Fornace AJ, Sonnenburg JL, McGovern DP, Borneman J, Braun J. PMID: 24781901; PMCID: PMC4992076.
      View in: PubMed   Mentions: 98     Fields:    Translation:HumansAnimalsCells
    103. Adenovirus E4ORF1-induced MYC activation promotes host cell anabolic glucose metabolism and virus replication. Cell Metab. 2014 Apr 01; 19(4):694-701. Thai M, Graham NA, Braas D, Nehil M, Komisopoulou E, Kurdistani SK, McCormick F, Graeber TG, Christofk HR. PMID: 24703700; PMCID: PMC4294542.
      View in: PubMed   Mentions: 129     Fields:    Translation:HumansCells
    104. CTLA4 blockade broadens the peripheral T-cell receptor repertoire. Clin Cancer Res. 2014 May 01; 20(9):2424-32. Robert L, Tsoi J, Wang X, Emerson R, Homet B, Chodon T, Mok S, Huang RR, Cochran AJ, Comin-Anduix B, Koya RC, Graeber TG, Robins H, Ribas A. PMID: 24583799; PMCID: PMC4008652.
      View in: PubMed   Mentions: 202     Fields:    Translation:HumansCells
    105. Phosphoproteomic analysis of platelets activated by pro-thrombotic oxidized phospholipids and thrombin. PLoS One. 2014; 9(1):e84488. Zimman A, Titz B, Komisopoulou E, Biswas S, Graeber TG, Podrez EA. PMID: 24400094; PMCID: PMC3882224.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansCells
    106. COX-2 inhibition prevents the appearance of cutaneous squamous cell carcinomas accelerated by BRAF inhibitors. Mol Oncol. 2014 Mar; 8(2):250-60. Escuin-Ordinas H, Atefi M, Fu Y, Cass A, Ng C, Huang RR, Yashar S, Comin-Anduix B, Avramis E, Cochran AJ, Marais R, Lo RS, Graeber TG, Herschman HR, Ribas A. PMID: 24345644; PMCID: PMC3943738.
      View in: PubMed   Mentions: 25     Fields:    
    107. Metastatic castration-resistant prostate cancer reveals intrapatient similarity and interpatient heterogeneity of therapeutic kinase targets. Proc Natl Acad Sci U S A. 2013 Dec 03; 110(49):E4762-9. Drake JM, Graham NA, Lee JK, Stoyanova T, Faltermeier CM, Sud S, Titz B, Huang J, Pienta KJ, Graeber TG, Witte ON. PMID: 24248375; PMCID: PMC3856845.
      View in: PubMed   Mentions: 69     Fields:    Translation:HumansCells
    108. Inhibition of CSF-1 receptor improves the antitumor efficacy of adoptive cell transfer immunotherapy. Cancer Res. 2014 Jan 01; 74(1):153-161. Mok S, Koya RC, Tsui C, Xu J, Robert L, Wu L, Graeber T, West BL, Bollag G, Ribas A. PMID: 24247719; PMCID: PMC3947337.
      View in: PubMed   Mentions: 175     Fields:    Translation:AnimalsCells
    109. BACH2 mediates negative selection and p53-dependent tumor suppression at the pre-B cell receptor checkpoint. Nat Med. 2013 Aug; 19(8):1014-22. Swaminathan S, Huang C, Geng H, Chen Z, Harvey R, Kang H, Ng C, Titz B, Hurtz C, Sadiyah MF, Nowak D, Thoennissen GB, Rand V, Graeber TG, Koeffler HP, Carroll WL, Willman CL, Hall AG, Igarashi K, Melnick A, Müschen M. PMID: 23852341; PMCID: PMC3954721.
      View in: PubMed   Mentions: 49     Fields:    Translation:AnimalsCells
    110. Integrative analysis of the microbiome and metabolome of the human intestinal mucosal surface reveals exquisite inter-relationships. Microbiome. 2013 Jun 05; 1(1):17. McHardy IH, Goudarzi M, Tong M, Ruegger PM, Schwager E, Weger JR, Graeber TG, Sonnenburg JL, Horvath S, Huttenhower C, McGovern DP, Fornace AJ, Borneman J, Braun J. PMID: 24450808; PMCID: PMC3971612.
      View in: PubMed   Mentions: 148     Fields:    
    111. Doxycycline alters metabolism and proliferation of human cell lines. PLoS One. 2013; 8(5):e64561. Ahler E, Sullivan WJ, Cass A, Braas D, York AG, Bensinger SJ, Graeber TG, Christofk HR. PMID: 23741339; PMCID: PMC3669316.
      View in: PubMed   Mentions: 86     Fields:    Translation:HumansCells
    112. Sterol regulatory element-binding proteins are essential for the metabolic programming of effector T cells and adaptive immunity. Nat Immunol. 2013 May; 14(5):489-99. Kidani Y, Elsaesser H, Hock MB, Vergnes L, Williams KJ, Argus JP, Marbois BN, Komisopoulou E, Wilson EB, Osborne TF, Graeber TG, Reue K, Brooks DG, Bensinger SJ. PMID: 23563690; PMCID: PMC3652626.
      View in: PubMed   Mentions: 258     Fields:    Translation:AnimalsCells
    113. An inhibitor of mutant IDH1 delays growth and promotes differentiation of glioma cells. Science. 2013 May 03; 340(6132):626-30. Rohle D, Popovici-Muller J, Palaskas N, Turcan S, Grommes C, Campos C, Tsoi J, Clark O, Oldrini B, Komisopoulou E, Kunii K, Pedraza A, Schalm S, Silverman L, Miller A, Wang F, Yang H, Chen Y, Kernytsky A, Rosenblum MK, Liu W, Biller SA, Su SM, Brennan CW, Chan TA, Graeber TG, Yen KE, Mellinghoff IK. PMID: 23558169; PMCID: PMC3985613.
      View in: PubMed   Mentions: 596     Fields:    Translation:AnimalsCells
    114. Type I interferon suppresses type II interferon-triggered human anti-mycobacterial responses. Science. 2013 Mar 22; 339(6126):1448-53. Teles RM, Graeber TG, Krutzik SR, Montoya D, Schenk M, Lee DJ, Komisopoulou E, Kelly-Scumpia K, Chun R, Iyer SS, Sarno EN, Rea TH, Hewison M, Adams JS, Popper SJ, Relman DA, Stenger S, Bloom BR, Cheng G, Modlin RL. PMID: 23449998; PMCID: PMC3653587.
      View in: PubMed   Mentions: 194     Fields:    Translation:HumansCells
    115. An essential requirement for the SCAP/SREBP signaling axis to protect cancer cells from lipotoxicity. Cancer Res. 2013 May 01; 73(9):2850-62. Williams KJ, Argus JP, Zhu Y, Wilks MQ, Marbois BN, York AG, Kidani Y, Pourzia AL, Akhavan D, Lisiero DN, Komisopoulou E, Henkin AH, Soto H, Chamberlain BT, Vergnes L, Jung ME, Torres JZ, Liau LM, Christofk HR, Prins RM, Mischel PS, Reue K, Graeber TG, Bensinger SJ. PMID: 23440422; PMCID: PMC3919498.
      View in: PubMed   Mentions: 105     Fields:    Translation:HumansAnimalsCells
    116. Host immunity contributes to the anti-melanoma activity of BRAF inhibitors. J Clin Invest. 2013 Mar; 123(3):1371-81. Knight DA, Ngiow SF, Li M, Parmenter T, Mok S, Cass A, Haynes NM, Kinross K, Yagita H, Koya RC, Graeber TG, Ribas A, McArthur GA, Smyth MJ. PMID: 23454771; PMCID: PMC3582139.
      View in: PubMed   Mentions: 138     Fields:    Translation:HumansAnimalsCells
    117. Phosphoproteomic analysis of aortic endothelial cells activated by oxidized phospholipids. Methods Mol Biol. 2013; 1000:53-69. Zimman A, Berliner JA, Graeber TG. PMID: 23585084.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    118. Glucose deprivation activates a metabolic and signaling amplification loop leading to cell death. Mol Syst Biol. 2012 Jun 26; 8:589. Graham NA, Tahmasian M, Kohli B, Komisopoulou E, Zhu M, Vivanco I, Teitell MA, Wu H, Ribas A, Lo RS, Mellinghoff IK, Mischel PS, Graeber TG. PMID: 22735335; PMCID: PMC3397414.
      View in: PubMed   Mentions: 91     Fields:    Translation:HumansCells
    119. BRAF inhibitor vemurafenib improves the antitumor activity of adoptive cell immunotherapy. Cancer Res. 2012 Aug 15; 72(16):3928-37. Koya RC, Mok S, Otte N, Blacketor KJ, Comin-Anduix B, Tumeh PC, Minasyan A, Graham NA, Graeber TG, Chodon T, Ribas A. PMID: 22693252; PMCID: PMC3422880.
      View in: PubMed   Mentions: 109     Fields:    Translation:HumansAnimalsCells
    120. NOD2 triggers an interleukin-32-dependent human dendritic cell program in leprosy. Nat Med. 2012 Mar 25; 18(4):555-63. Schenk M, Krutzik SR, Sieling PA, Lee DJ, Teles RM, Ochoa MT, Komisopoulou E, Sarno EN, Rea TH, Graeber TG, Kim S, Cheng G, Modlin RL. PMID: 22447076; PMCID: PMC3348859.
      View in: PubMed   Mentions: 60     Fields:    
    121. Determining PTEN functional status by network component deduced transcription factor activities. PLoS One. 2012; 7(2):e31053. Tran LM, Chang CJ, Plaisier S, Wu S, Dang J, Mischel PS, Liao JC, Graeber TG, Wu H. PMID: 22347425; PMCID: PMC3275574.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimalsCells
    122. MicroRNA-21 targets the vitamin D-dependent antimicrobial pathway in leprosy. Nat Med. 2012 Jan 29; 18(2):267-73. Liu PT, Wheelwright M, Teles R, Komisopoulou E, Edfeldt K, Ferguson B, Mehta MD, Vazirnia A, Rea TH, Sarno EN, Graeber TG, Modlin RL. PMID: 22286305; PMCID: PMC3274599.
      View in: PubMed   Mentions: 109     Fields:    
    123. Oncogene-specific activation of tyrosine kinase networks during prostate cancer progression. Proc Natl Acad Sci U S A. 2012 Jan 31; 109(5):1643-8. Drake JM, Graham NA, Stoyanova T, Sedghi A, Goldstein AS, Cai H, Smith DA, Zhang H, Komisopoulou E, Huang J, Graeber TG, Witte ON. PMID: 22307624; PMCID: PMC3277127.
      View in: PubMed   Mentions: 87     Fields:    Translation:AnimalsCells
    124. RAF inhibitor resistance is mediated by dimerization of aberrantly spliced BRAF(V600E). Nature. 2011 Nov 23; 480(7377):387-90. Poulikakos PI, Persaud Y, Janakiraman M, Kong X, Ng C, Moriceau G, Shi H, Atefi M, Titz B, Gabay MT, Salton M, Dahlman KB, Tadi M, Wargo JA, Flaherty KT, Kelley MC, Misteli T, Chapman PB, Sosman JA, Graeber TG, Ribas A, Lo RS, Rosen N, Solit DB. PMID: 22113612; PMCID: PMC3266695.
      View in: PubMed   Mentions: 701     Fields:    
    125. A metaproteomic approach to study human-microbial ecosystems at the mucosal luminal interface. PLoS One. 2011; 6(11):e26542. Li X, LeBlanc J, Truong A, Vuthoori R, Chen SS, Lustgarten JL, Roth B, Allard J, Ippoliti A, Presley LL, Borneman J, Bigbee WL, Gopalakrishnan V, Graeber TG, Elashoff D, Braun J, Goodglick L. PMID: 22132074; PMCID: PMC3221670.
      View in: PubMed   Mentions: 42     Fields:    Translation:HumansCells
    126. An integrated approach to dissecting oncogene addiction implicates a Myb-coordinated self-renewal program as essential for leukemia maintenance. Genes Dev. 2011 Aug 01; 25(15):1628-40. Zuber J, Rappaport AR, Luo W, Wang E, Chen C, Vaseva AV, Shi J, Weissmueller S, Fellmann C, Fellman C, Taylor MJ, Weissenboeck M, Graeber TG, Kogan SC, Vakoc CR, Lowe SW. PMID: 21828272; PMCID: PMC3182026.
      View in: PubMed   Mentions: 143     Fields:    Translation:Animals
    127. 18F-fluorodeoxy-glucose positron emission tomography marks MYC-overexpressing human basal-like breast cancers. Cancer Res. 2011 Aug 01; 71(15):5164-74. Palaskas N, Larson SM, Schultz N, Komisopoulou E, Wong J, Rohle D, Campos C, Yannuzzi N, Osborne JR, Linkov I, Kastenhuber ER, Taschereau R, Plaisier SB, Tran C, Heguy A, Wu H, Sander C, Phelps ME, Brennan C, Port E, Huse JT, Graeber TG, Mellinghoff IK. PMID: 21646475; PMCID: PMC3148325.
      View in: PubMed   Mentions: 73     Fields:    
    128. Cell autonomous role of PTEN in regulating castration-resistant prostate cancer growth. Cancer Cell. 2011 Jun 14; 19(6):792-804. Mulholland DJ, Tran LM, Li Y, Cai H, Morim A, Wang S, Plaisier S, Garraway IP, Huang J, Graeber TG, Wu H. PMID: 21620777; PMCID: PMC3157296.
      View in: PubMed   Mentions: 289     Fields:    
    129. BCL6 enables Ph+ acute lymphoblastic leukaemia cells to survive BCR-ABL1 kinase inhibition. Nature. 2011 May 19; 473(7347):384-8. Duy C, Hurtz C, Shojaee S, Cerchietti L, Geng H, Swaminathan S, Klemm L, Kweon SM, Nahar R, Braig M, Park E, Kim YM, Hofmann WK, Herzog S, Jumaa H, Koeffler HP, Yu JJ, Heisterkamp N, Graeber TG, Wu H, Ye BH, Melnick A, Müschen M. PMID: 21593872; PMCID: PMC3597744.
      View in: PubMed   Mentions: 98     Fields:    
    130. Global phosphoproteomics reveals crosstalk between Bcr-Abl and negative feedback mechanisms controlling Src signaling. Sci Signal. 2011 Mar 29; 4(166):ra18. Rubbi L, Titz B, Brown L, Galvan E, Komisopoulou E, Chen SS, Low T, Tahmasian M, Skaggs B, Müschen M, Pellegrini M, Graeber TG. PMID: 21447799; PMCID: PMC4057100.
      View in: PubMed   Mentions: 30     Fields:    Translation:HumansCells
    131. The impact of ex vivo clinical grade activation protocols on human T-cell phenotype and function for the generation of genetically modified cells for adoptive cell transfer therapy. J Immunother. 2010 Oct; 33(8):759-68. Tumeh PC, Koya RC, Chodon T, Graham NA, Graeber TG, Comin-Anduix B, Ribas A. PMID: 20842061; PMCID: PMC3114626.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansCells
    132. Integrated microfluidic and imaging platform for a kinase activity radioassay to analyze minute patient cancer samples. Cancer Res. 2010 Nov 01; 70(21):8299-308. Fang C, Wang Y, Vu NT, Lin WY, Hsieh YT, Rubbi L, Phelps ME, Müschen M, Kim YM, Chatziioannou AF, Tseng HR, Graeber TG. PMID: 20837665; PMCID: PMC3989903.
      View in: PubMed   Mentions: 14     Fields:    
    133. Rank-rank hypergeometric overlap: identification of statistically significant overlap between gene-expression signatures. Nucleic Acids Res. 2010 Sep; 38(17):e169. Plaisier SB, Taschereau R, Wong JA, Graeber TG. PMID: 20660011; PMCID: PMC2943622.
      View in: PubMed   Mentions: 243     Fields:    Translation:HumansAnimals
    134. A microfluidic platform for systems pathology: multiparameter single-cell signaling measurements of clinical brain tumor specimens. Cancer Res. 2010 Aug 01; 70(15):6128-38. Sun J, Masterman-Smith MD, Graham NA, Jiao J, Mottahedeh J, Laks DR, Ohashi M, DeJesus J, Kamei K, Lee KB, Wang H, Yu ZT, Lu YT, Hou S, Li K, Liu M, Zhang N, Wang S, Angenieux B, Panosyan E, Samuels ER, Park J, Williams D, Konkankit V, Nathanson D, van Dam RM, Phelps ME, Wu H, Liau LM, Mischel PS, Lazareff JA, Kornblum HI, Yong WH, Graeber TG, Tseng HR. PMID: 20631065; PMCID: PMC3163840.
      View in: PubMed   Mentions: 39     Fields:    
    135. Activation of aortic endothelial cells by oxidized phospholipids: a phosphoproteomic analysis. J Proteome Res. 2010 Jun 04; 9(6):2812-24. Zimman A, Chen SS, Komisopoulou E, Titz B, Martínez-Pinna R, Kafi A, Berliner JA, Graeber TG. PMID: 20307106; PMCID: PMC2922471.
      View in: PubMed   Mentions: 18     Fields:    
    136. Fyn and SRC are effectors of oncogenic epidermal growth factor receptor signaling in glioblastoma patients. Cancer Res. 2009 Sep 01; 69(17):6889-98. Lu KV, Zhu S, Cvrljevic A, Huang TT, Sarkaria S, Ahkavan D, Dang J, Dinca EB, Plaisier SB, Oderberg I, Lee Y, Chen Z, Caldwell JS, Xie Y, Loo JA, Seligson D, Chakravari A, Lee FY, Weinmann R, Cloughesy TF, Nelson SF, Bergers G, Graeber T, Furnari FB, James CD, Cavenee WK, Johns TG, Mischel PS. PMID: 19690143; PMCID: PMC2770839.
      View in: PubMed   Mentions: 90     Fields:    
    137. Phosphorylation of the ATP-binding loop directs oncogenicity of drug-resistant BCR-ABL mutants. Proc Natl Acad Sci U S A. 2006 Dec 19; 103(51):19466-71. Skaggs BJ, Gorre ME, Ryvkin A, Burgess MR, Xie Y, Han Y, Komisopoulou E, Brown LM, Loo JA, Landaw EM, Sawyers CL, Graeber TG. PMID: 17164333; PMCID: PMC1698443.
      View in: PubMed   Mentions: 52     Fields:    Translation:AnimalsCells
    138. Vascular endothelial growth factor receptor 2 plays a role in the activation of aortic endothelial cells by oxidized phospholipids. Arterioscler Thromb Vasc Biol. 2007 Feb; 27(2):332-8. Zimman A, Mouillesseaux KP, Le T, Gharavi NM, Ryvkin A, Graeber TG, Chen TT, Watson AD, Berliner JA. PMID: 17110601.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansCells
    139. TLR activation triggers the rapid differentiation of monocytes into macrophages and dendritic cells. Nat Med. 2005 Jun; 11(6):653-60. Krutzik SR, Tan B, Li H, Ochoa MT, Liu PT, Sharfstein SE, Graeber TG, Sieling PA, Liu YJ, Rea TH, Bloom BR, Modlin RL. PMID: 15880118; PMCID: PMC1409736.
      View in: PubMed   Mentions: 123     Fields:    Translation:HumansCells
    140. Cross-species comparisons of cancer signaling. Nat Genet. 2005 Jan; 37(1):7-8. Graeber TG, Sawyers CL. PMID: 15624012.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimalsCells
    141. Visualization and interpretation of protein networks in Mycobacterium tuberculosis based on hierarchical clustering of genome-wide functional linkage maps. Nucleic Acids Res. 2003 Dec 15; 31(24):7099-109. Strong M, Graeber TG, Beeby M, Pellegrini M, Thompson MJ, Yeates TO, Eisenberg D. PMID: 14654685; PMCID: PMC291866.
      View in: PubMed   Mentions: 15     Fields:    Translation:Cells
    142. Use of genetic profiling in leprosy to discriminate clinical forms of the disease. Science. 2003 Sep 12; 301(5639):1527-30. Bleharski JR, Li H, Meinken C, Graeber TG, Ochoa MT, Yamamura M, Burdick A, Sarno EN, Wagner M, Röllinghoff M, Rea TH, Colonna M, Stenger S, Bloom BR, Eisenberg D, Modlin RL. PMID: 12970564.
      View in: PubMed   Mentions: 57     Fields:    Translation:HumansCells
    143. Myc-driven murine prostate cancer shares molecular features with human prostate tumors. Cancer Cell. 2003 Sep; 4(3):223-38. Ellwood-Yen K, Graeber TG, Wongvipat J, Iruela-Arispe ML, Zhang J, Matusik R, Thomas GV, Sawyers CL. PMID: 14522256.
      View in: PubMed   Mentions: 332     Fields:    Translation:HumansAnimals
    144. Heterogeneity of molecular targets on clonal cancer lines derived from a novel hormone-refractory prostate cancer tumor system. Prostate. 2003 Jun 01; 55(4):299-307. Freedland SJ, Pantuck AJ, Paik SH, Zisman A, Graeber TG, Eisenberg D, McBride WH, Nguyen D, Tso CL, Belldegrun AS. PMID: 12712409.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimalsCells
    145. Gene expression in epithelial ovarian carcinoma. Oncogene. 2002 Sep 12; 21(41):6289-98. Matei D, Graeber TG, Baldwin RL, Karlan BY, Rao J, Chang DD. PMID: 12214269.
      View in: PubMed   Mentions: 20     Fields:    Translation:Humans
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