-
Double assurance in the induction of axial development by egg dorsal determinants in Xenopus embryos. Proc Natl Acad Sci U S A. 2025 Feb 18; 122(7):e2421772122.
Azbazdar Y, De Robertis EM. PMID: 39928870; PMCID: PMC11848351.
View in:
PubMed Mentions: Fields:
-
Molecular analysis of a self-organizing signaling pathway for Xenopus axial patterning from egg to tailbud. Proc Natl Acad Sci U S A. 2024 Jul 09; 121(28):e2408346121.
Azbazdar Y, De Robertis EM. PMID: 38968117; PMCID: PMC11252917.
View in:
PubMed Mentions: Fields:
Translation:
AnimalsCells
-
Na,K-ATPase activity promotes macropinocytosis in colon cancer via Wnt signaling. Biol Open. 2024 May 15; 13(5).
Tejeda-Muñoz N, Azbazdar Y, Sosa EA, Monka J, Wei PS, Binder G, Mei KC, Kurmangaliyev YZ, De Robertis EM. PMID: 38713004; PMCID: PMC11139033.
View in:
PubMed Mentions:
2 Fields:
Translation:
HumansAnimalsCells
-
Celebrating the centennial of the most famous experiment in embryology: Hilde Mangold, Hans Spemann and the organizer. Cells Dev. 2024 Jun; 178:203921.
De Robertis EM, Driever W, Mayor R. PMID: 38636902.
View in:
PubMed Mentions:
1 Fields:
Translation:
HumansAnimals
-
Strategies to decrease inequalities in cancer therapeutics, care and prevention: Proceedings on a conference organized by the Pontifical Academy of Sciences and the European Academy of Cancer Sciences, Vatican City, February 23-24, 2023. Mol Oncol. 2024 Feb; 18(2):245-279.
Ringborg U, von Braun J, Celis J, Baumann M, Berns A, Eggermont A, Heard E, Heitor M, Chandy M, Chen CJ, Costa A, De Lorenzo F, De Robertis EM, Dubee FC, Ernberg I, Gabriel M, Helland Å, Henrique R, Jönsson B, Kallioniemi O, Korbel J, Krause M, Lowy DR, Michielin O, Nagy P, Oberst S, Paglia V, Parker MI, Ryan K, Sawyers CL, Schüz J, Silkaitis K, Solary E, Thomas D, Turkson P, Weiderpass E, Yang H. PMID: 38135904; PMCID: PMC10850793.
View in:
PubMed Mentions:
5 Fields:
Translation:
Humans
-
Head organizer: Cerberus and IGF cooperate in brain induction in Xenopus embryos. Cells Dev. 2023 Dec 16; 203897.
Azbazdar Y, Pera EM, De Robertis EM. PMID: 38109998.
View in:
PubMed Mentions:
1 Fields:
-
The early dorsal signal in vertebrate embryos requires endolysosomal membrane trafficking. Bioessays. 2024 Jan; 46(1):e2300179.
Azbazdar Y, De Robertis EM. PMID: 37983969.
View in:
PubMed Mentions:
2 Fields:
Translation:
AnimalsCells
-
The PMA phorbol ester tumor promoter increases canonical Wnt signaling via macropinocytosis. Elife. 2023 Oct 30; 12.
Tejeda-Munoz N, Azbazdar Y, Monka J, Binder G, Dayrit A, Ayala R, O'Brien N, De Robertis EM. PMID: 37902809; PMCID: PMC10615368.
View in:
PubMed Mentions:
5 Fields:
Translation:
HumansAnimalsCells
-
Addition of exogenous diacylglycerol enhances Wnt/ß-catenin signaling through stimulation of macropinocytosis. iScience. 2023 Oct 20; 26(10):108075.
Azbazdar Y, Tejeda-Munoz N, Monka JC, Dayrit A, Binder G, Ozhan G, De Robertis EM. PMID: 37860772; PMCID: PMC10582480.
View in:
PubMed Mentions:
2
-
The PMA Phorbol Ester Tumor Promoter Increases Canonical Wnt Signaling Via Macropinocytosis. bioRxiv. 2023 Aug 30.
Tejeda-Muñoz N, Azbazdar Y, Monka J, Binder G, Dayrit A, Ayala R, O'Brien N, De Robertis EM. PMID: 37333286; PMCID: PMC10274750.
View in:
PubMed Mentions:
-
The developmental gene Chordin is amplified and expressed in human cancers. Mol Cell Oncol. 2023; 10(1):2218147.
Sosa E, De Robertis EM. PMID: 37260544; PMCID: PMC10228393.
View in:
PubMed Mentions:
1
-
Protocol for culturing and imaging of ectodermal cells from Xenopus. STAR Protoc. 2022 Sep 16; 3(3):101455.
Tejeda-Muñoz N, Monka J, De Robertis EM. PMID: 35839770; PMCID: PMC9293668.
View in:
PubMed Mentions:
2 Fields:
Translation:
AnimalsCells
-
The impact of developmental biology in the last 100 years. Dev Biol. 2022 09; 489:118-121.
De Robertis EM. PMID: 35716718.
View in:
PubMed Mentions: Fields:
-
Lysosomes are required for early dorsal signaling in the Xenopus embryo. Proc Natl Acad Sci U S A. 2022 Apr 26; 119(17):e2201008119.
Tejeda-Muñoz N, De Robertis EM. PMID: 35446621; PMCID: PMC9170039.
View in:
PubMed Mentions:
9 Fields:
Translation:
AnimalsCells
-
Evo-Devo of Urbilateria and its larval forms. Dev Biol. 2022 07; 487:10-20.
De Robertis EM, Tejeda-Muñoz N. PMID: 35443190.
View in:
PubMed Mentions:
10 Fields:
Translation:
Animals
-
Canonical Wnt signaling induces focal adhesion and Integrin beta-1 endocytosis. iScience. 2022 Apr 15; 25(4):104123.
Tejeda-Muñoz N, Morselli M, Moriyama Y, Sheladiya P, Pellegrini M, De Robertis EM. PMID: 35402867; PMCID: PMC8987407.
View in:
PubMed Mentions:
8
-
Wnt, GSK3, and Macropinocytosis. Subcell Biochem. 2022; 98:169-187.
Tejeda-Muñoz N, De Robertis EM. PMID: 35378708.
View in:
PubMed Mentions:
7 Fields:
Translation:
Cells
-
A Brief History of Xenopus in Biology. Cold Spring Harb Protoc. 2021 12 01; 2021(12).
De Robertis EM, Gurdon JB. PMID: 33785561.
View in:
PubMed Mentions:
7 Fields:
Translation:
AnimalsCells
-
Cell Biology of Canonical Wnt Signaling. Annu Rev Cell Dev Biol. 2021 10 06; 37:369-389.
Albrecht LV, Tejeda-Muñoz N, De Robertis EM. PMID: 34196570.
View in:
PubMed Mentions:
58 Fields:
Translation:
HumansCells
-
The cytokine FAM3B/PANDER is an FGFR ligand that promotes posterior development in Xenopus. Proc Natl Acad Sci U S A. 2021 05 18; 118(20).
Zhang F, Zhu X, Wang P, He Q, Huang H, Zheng T, Li Y, Jia H, Xu L, Zhao H, Colozza G, Tao Q, De Robertis EM, Ding Y. PMID: 33975953; PMCID: PMC8158011.
View in:
PubMed Mentions:
5 Fields:
Translation:
HumansAnimalsCells
-
Wnt-inducible Lrp6-APEX2 interacting proteins identify ESCRT machinery and Trk-fused gene as components of the Wnt signaling pathway. Sci Rep. 2020 12 09; 10(1):21555.
Colozza G, Jami-Alahmadi Y, Dsouza A, Tejeda-Muñoz N, Albrecht LV, Sosa EA, Wohlschlegel JA, De Robertis EM. PMID: 33299006; PMCID: PMC7726150.
View in:
PubMed Mentions:
18 Fields:
Translation:
HumansCells
-
Dact-4 is a Xenopus laevis Spemann organizer gene related to the Dapper/Frodo antagonist of β-catenin family of proteins. Gene Expr Patterns. 2020 12; 38:119153.
Colozza G, De Robertis EM. PMID: 33186756.
View in:
PubMed Mentions:
2 Fields:
Translation:
Animals
-
Protocol for Probing Regulated Lysosomal Activity and Function in Living Cells. STAR Protoc. 2020 12 18; 1(3):100132.
Albrecht LV, Tejeda-Muñoz N, De Robertis EM. PMID: 33377026; PMCID: PMC7757114.
View in:
PubMed Mentions:
9 Fields:
Translation:
HumansAnimalsCells
-
GSK3 Inhibits Macropinocytosis and Lysosomal Activity through the Wnt Destruction Complex Machinery. Cell Rep. 2020 07 28; 32(4):107973.
Albrecht LV, Tejeda-Muñoz N, Bui MH, Cicchetto AC, Di Biagio D, Colozza G, Schmid E, Piccolo S, Christofk HR, De Robertis EM. PMID: 32726636; PMCID: PMC7666578.
View in:
PubMed Mentions:
33 Fields:
Translation:
AnimalsCells
-
Wnt canonical pathway activates macropinocytosis and lysosomal degradation of extracellular proteins. Proc Natl Acad Sci U S A. 2019 05 21; 116(21):10402-10411.
Tejeda-Muñoz N, Albrecht LV, Bui MH, De Robertis EM. PMID: 31061124; PMCID: PMC6534993.
View in:
PubMed Mentions:
51 Fields:
Translation:
HumansAnimalsCells
-
Canonical Wnt is inhibited by targeting one-carbon metabolism through methotrexate or methionine deprivation. Proc Natl Acad Sci U S A. 2019 02 19; 116(8):2987-2995.
Albrecht LV, Bui MH, De Robertis EM. PMID: 30679275; PMCID: PMC6386671.
View in:
PubMed Mentions:
34 Fields:
Translation:
HumansCells
-
Transcriptome analysis of regeneration during Xenopus laevis experimental twinning. Int J Dev Biol. 2019; 63(6-7):301-309.
Sosa EA, Moriyama Y, Ding Y, Tejeda-Muñoz N, Colozza G, De Robertis EM. PMID: 31250914; PMCID: PMC7032064.
View in:
PubMed Mentions:
1 Fields:
Translation:
AnimalsCells
-
Bighead is a Wnt antagonist secreted by the Xenopus Spemann organizer that promotes Lrp6 endocytosis. Proc Natl Acad Sci U S A. 2018 09 25; 115(39):E9135-E9144.
Ding Y, Colozza G, Sosa EA, Moriyama Y, Rundle S, Salwinski L, De Robertis EM. PMID: 30209221; PMCID: PMC6166843.
View in:
PubMed Mentions:
21 Fields:
Translation:
AnimalsCells
-
Arginine methylation is required for canonical Wnt signaling and endolysosomal trafficking. Proc Natl Acad Sci U S A. 2018 06 05; 115(23):E5317-E5325.
Albrecht LV, Ploper D, Tejeda-Muñoz N, De Robertis EM. PMID: 29773710; PMCID: PMC6003351.
View in:
PubMed Mentions:
41 Fields:
Translation:
HumansCells
-
Embryonic regeneration by relocalization of the Spemann organizer during twinning in Xenopus. Proc Natl Acad Sci U S A. 2018 05 22; 115(21):E4815-E4822.
Moriyama Y, De Robertis EM. PMID: 29686106; PMCID: PMC6003488.
View in:
PubMed Mentions:
7 Fields:
Translation:
AnimalsCells
-
Angiopoietin-like 4 Is a Wnt Signaling Antagonist that Promotes LRP6 Turnover. Dev Cell. 2017 10 09; 43(1):71-82.e6.
Kirsch N, Chang LS, Koch S, Glinka A, Dolde C, Colozza G, Benitez MDJ, De Robertis EM, Niehrs C. PMID: 29017031.
View in:
PubMed Mentions:
35 Fields:
Translation:
HumansAnimalsCells
-
Generation of animal form by the Chordin/Tolloid/BMP gradient: 100 years after D'Arcy Thompson. Dev Growth Differ. 2017 Sep; 59(7):580-592.
De Robertis EM, Moriyama Y, Colozza G. PMID: 28815565.
View in:
PubMed Mentions:
5 Fields:
Translation:
AnimalsCells
-
Spemann organizer transcriptome induction by early beta-catenin, Wnt, Nodal, and Siamois signals in Xenopus laevis. Proc Natl Acad Sci U S A. 2017 04 11; 114(15):E3081-E3090.
Ding Y, Ploper D, Sosa EA, Colozza G, Moriyama Y, Benitez MD, Zhang K, Merkurjev D, De Robertis EM. PMID: 28348214; PMCID: PMC5393196.
View in:
PubMed Mentions:
26 Fields:
Translation:
AnimalsCells
-
Genome-wide analysis of dorsal and ventral transcriptomes of the Xenopus laevis gastrula. Dev Biol. 2017 06 15; 426(2):176-187.
Ding Y, Colozza G, Zhang K, Moriyama Y, Ploper D, Sosa EA, Benitez MDJ, De Robertis EM. PMID: 27016259; PMCID: PMC5033668.
View in:
PubMed Mentions:
26 Fields:
Translation:
AnimalsCells
-
The Chordin Morphogenetic Pathway. Curr Top Dev Biol. 2016; 116:231-45.
De Robertis EM, Moriyama Y. PMID: 26970622.
View in:
PubMed Mentions:
8 Fields:
Translation:
AnimalsCells
-
Sperm Motility Requires Wnt/GSK3 Stabilization of Proteins. Dev Cell. 2015 Nov 23; 35(4):401-2.
De Robertis EM, Ploper D. PMID: 26609954.
View in:
PubMed Mentions:
4 Fields:
Translation:
AnimalsCells
-
Morpholinos: Antisense and Sensibility. Dev Cell. 2015 Oct 26; 35(2):145-9.
Blum M, De Robertis EM, Wallingford JB, Niehrs C. PMID: 26506304.
View in:
PubMed Mentions:
83 Fields:
Translation:
HumansAnimals
-
EMBRYO DEVELOPMENT. BMP gradients: A paradigm for morphogen-mediated developmental patterning. Science. 2015 Jun 26; 348(6242):aaa5838.
Bier E, De Robertis EM. PMID: 26113727.
View in:
PubMed Mentions:
121 Fields:
Translation:
Animals
-
Wnt Signaling Translocates Lys48-Linked Polyubiquitinated Proteins to the Lysosomal Pathway. Cell Rep. 2015 May 26; 11(8):1151-9.
Kim H, Vick P, Hedtke J, Ploper D, De Robertis EM. PMID: 26004177.
View in:
PubMed Mentions:
22 Fields:
Translation:
HumansCells
-
The MITF family of transcription factors: Role in endolysosomal biogenesis, Wnt signaling, and oncogenesis. Pharmacol Res. 2015 Sep; 99:36-43.
Ploper D, De Robertis EM. PMID: 26003288.
View in:
PubMed Mentions:
36 Fields:
Translation:
HumansAnimalsCells
-
Point mutations in the tumor suppressor Smad4/DPC4 enhance its phosphorylation by GSK3 and reversibly inactivate TGF-β signaling. Mol Cell Oncol. 2016 Jan; 3(1):e1025181.
Demagny H, De Robertis EM. PMID: 27308538; PMCID: PMC4845174.
View in:
PubMed Mentions:
23
-
Smad4/DPC4: A barrier against tumor progression driven by RTK/Ras/Erk and Wnt/GSK3 signaling. Mol Cell Oncol. 2016 Mar; 3(2):e989133.
Demagny H, De Robertis EM. PMID: 27308623; PMCID: PMC4905428.
View in:
PubMed Mentions:
8
-
MITF drives endolysosomal biogenesis and potentiates Wnt signaling in melanoma cells. Proc Natl Acad Sci U S A. 2015 Feb 03; 112(5):E420-9.
Ploper D, Taelman VF, Robert L, Perez BS, Titz B, Chen HW, Graeber TG, von Euw E, Ribas A, De Robertis EM. PMID: 25605940; PMCID: PMC4321275.
View in:
PubMed Mentions:
137 Fields:
Translation:
HumansCells
-
Lessons from a great developmental biologist. Differentiation. 2014 Jul; 88(1):3-8.
De Robertis EM. PMID: 25455202; PMCID: PMC4286343.
View in:
PubMed Mentions:
1 Fields:
-
The tumor suppressor Smad4/DPC4 is regulated by phosphorylations that integrate FGF, Wnt, and TGF-β signaling. Cell Rep. 2014 Oct 23; 9(2):688-700.
Demagny H, Araki T, De Robertis EM. PMID: 25373906.
View in:
PubMed Mentions:
38 Fields:
Translation:
HumansAnimalsCells
-
Yoshiki Sasai 1962-2014. Cell. 2014 Sep 11; 158(6):1233-5.
De Robertis EM. PMID: 25349875.
View in:
PubMed Mentions:
1 Fields:
Translation:
HumansAnimalsCells
-
Yoshiki Sasai 1962–2014. Dev Cell. 2014 Sep 08; 30(5):509-11.
De Robertis EM. PMID: 25340213.
View in:
PubMed Mentions: Fields:
Translation:
HumansAnimalsCells
-
Maternal syntabulin is required for dorsal axis formation and is a germ plasm component in Xenopus. Differentiation. 2014 Jul; 88(1):17-26.
Colozza G, De Robertis EM. PMID: 24798204.
View in:
PubMed Mentions:
24 Fields:
Translation:
HumansAnimalsCells
-
Herbert Steinbeisser: a life with the Xenopus embryo. Int J Dev Biol. 2014; 58(5):299-302.
De Robertis EM, Niehrs C. PMID: 25354448.
View in:
PubMed Mentions: Fields:
Translation:
Animals
-
Chordin forms a self-organizing morphogen gradient in the extracellular space between ectoderm and mesoderm in the Xenopus embryo. Proc Natl Acad Sci U S A. 2013 Dec 17; 110(51):20372-9.
Plouhinec JL, Zakin L, Moriyama Y, De Robertis EM. PMID: 24284174; PMCID: PMC3870759.
View in:
PubMed Mentions:
43 Fields:
Translation:
AnimalsCells
-
Development: scaling to size by protease inhibition. Curr Biol. 2013 Aug 05; 23(15):R652-4.
De Robertis EM, Colozza G. PMID: 23928082.
View in:
PubMed Mentions:
2 Fields:
Translation:
Animals
-
Presenilin deficiency or lysosomal inhibition enhances Wnt signaling through relocalization of GSK3 to the late-endosomal compartment. Cell Rep. 2012 Nov 29; 2(5):1316-28.
Dobrowolski R, Vick P, Ploper D, Gumper I, Snitkin H, Sabatini DD, De Robertis EM. PMID: 23122960; PMCID: PMC3538832.
View in:
PubMed Mentions:
47 Fields:
Translation:
HumansAnimalsCells
-
Endocytic control of growth factor signalling: multivesicular bodies as signalling organelles. Nat Rev Mol Cell Biol. 2011 11 23; 13(1):53-60.
Dobrowolski R, De Robertis EM. PMID: 22108513; PMCID: PMC3374592.
View in:
PubMed Mentions:
93 Fields:
Translation:
HumansAnimalsCells
-
Phosphorylation of Mad controls competition between wingless and BMP signaling. Sci Signal. 2011 Oct 11; 4(194):ra68.
Eivers E, Demagny H, Choi RH, De Robertis EM. PMID: 21990430; PMCID: PMC3215398.
View in:
PubMed Mentions:
18 Fields:
Translation:
HumansAnimalsCells
-
Systems control of BMP morphogen flow in vertebrate embryos. Curr Opin Genet Dev. 2011 Dec; 21(6):696-703.
Plouhinec JL, Zakin L, De Robertis EM. PMID: 21937218; PMCID: PMC3224208.
View in:
PubMed Mentions:
23 Fields:
Translation:
AnimalsCells
-
Temporal pattern of the posterior expression of Wingless in Drosophila blastoderm. Gene Expr Patterns. 2011 Oct; 11(7):456-63.
Vorwald-Denholtz PP, De Robertis EM. PMID: 21821151; PMCID: PMC3200307.
View in:
PubMed Mentions:
8 Fields:
Translation:
AnimalsCells
-
Dorsal-ventral patterning: Crescent is a dorsally secreted Frizzled-related protein that competitively inhibits Tolloid proteases. Dev Biol. 2011 Apr 15; 352(2):317-28.
Ploper D, Lee HX, De Robertis EM. PMID: 21295563; PMCID: PMC3088358.
View in:
PubMed Mentions:
18 Fields:
Translation:
AnimalsCells
-
Wnt signaling requires sequestration of glycogen synthase kinase 3 inside multivesicular endosomes. Cell. 2010 Dec 23; 143(7):1136-48.
Taelman VF, Dobrowolski R, Plouhinec JL, Fuentealba LC, Vorwald PP, Gumper I, Sabatini DD, De Robertis EM. PMID: 21183076; PMCID: PMC3022472.
View in:
PubMed Mentions:
362 Fields:
Translation:
HumansAnimalsCells
-
Crossveinless-2 is required for the relocalization of Chordin protein within the vertebral field in mouse embryos. Dev Biol. 2010 Nov 01; 347(1):204-15.
Zakin L, Chang EY, Plouhinec JL, De Robertis EM. PMID: 20807528; PMCID: PMC2975673.
View in:
PubMed Mentions:
21 Fields:
Translation:
AnimalsCells
-
Wnt signaling in axial patterning and regeneration: lessons from planaria. Sci Signal. 2010 Jun 22; 3(127):pe21.
De Robertis EM. PMID: 20571126; PMCID: PMC3034647.
View in:
PubMed Mentions:
24 Fields:
Translation:
AnimalsCells
-
Drosophila Smad2 opposes Mad signaling during wing vein development. PLoS One. 2010 Apr 28; 5(4):e10383.
Sander V, Eivers E, Choi RH, De Robertis EM. PMID: 20442782; PMCID: PMC2860994.
View in:
PubMed Mentions:
11 Fields:
Translation:
AnimalsCells
-
The RNA-binding protein bicaudal C regulates polycystin 2 in the kidney by antagonizing miR-17 activity. Development. 2010 Apr; 137(7):1107-16.
Tran U, Zakin L, Schweickert A, Agrawal R, Döger R, Blum M, De Robertis EM, Wessely O. PMID: 20215348; PMCID: PMC2835326.
View in:
PubMed Mentions:
74 Fields:
Translation:
HumansAnimalsCells
-
Extracellular regulation of BMP signaling. Curr Biol. 2010 Feb 09; 20(3):R89-92.
Zakin L, De Robertis EM. PMID: 20144774; PMCID: PMC3034644.
View in:
PubMed Mentions:
38 Fields:
Translation:
AnimalsCells
-
Integration of BMP and Wnt signaling via vertebrate Smad1/5/8 and Drosophila Mad. Cytokine Growth Factor Rev. 2009; 20(5-6):357-65.
Eivers E, Demagny H, De Robertis EM. PMID: 19896409; PMCID: PMC2810204.
View in:
PubMed Mentions:
26 Fields:
Translation:
HumansAnimalsCells
-
Enzymatic regulation of pattern: BMP4 binds CUB domains of Tolloids and inhibits proteinase activity. Genes Dev. 2009 Nov 01; 23(21):2551-62.
Lee HX, Mendes FA, Plouhinec JL, De Robertis EM. PMID: 19884260; PMCID: PMC2779747.
View in:
PubMed Mentions:
25 Fields:
Translation:
AnimalsCells
-
Spemann's organizer and the self-regulation of embryonic fields. Mech Dev. 2009 Dec; 126(11-12):925-41.
De Robertis EM. PMID: 19733655; PMCID: PMC2803698.
View in:
PubMed Mentions:
73 Fields:
Translation:
Animals
-
Mad is required for wingless signaling in wing development and segment patterning in Drosophila. PLoS One. 2009 Aug 06; 4(8):e6543.
Eivers E, Fuentealba LC, Sander V, Clemens JC, Hartnett L, De Robertis EM. PMID: 19657393; PMCID: PMC2717371.
View in:
PubMed Mentions:
28 Fields:
Translation:
AnimalsCells
-
Systems biology of the self-regulating morphogenetic gradient of the Xenopus gastrula. Cold Spring Harb Perspect Biol. 2009 Aug; 1(2):a001701.
Plouhinec JL, De Robertis EM. PMID: 20066084; PMCID: PMC2742089.
View in:
PubMed Mentions:
20 Fields:
Translation:
AnimalsCells
-
The molecular ancestry of segmentation mechanisms. Proc Natl Acad Sci U S A. 2008 Oct 28; 105(43):16411-2.
De Robertis EM. PMID: 18948592; PMCID: PMC2575432.
View in:
PubMed Mentions:
18 Fields:
Translation:
Animals
-
Development of the vertebral morphogenetic field in the mouse: interactions between Crossveinless-2 and Twisted Gastrulation. Dev Biol. 2008 Nov 01; 323(1):6-18.
Zakin L, Metzinger CA, Chang EY, Coffinier C, De Robertis EM. PMID: 18789316; PMCID: PMC2647368.
View in:
PubMed Mentions:
30 Fields:
Translation:
AnimalsCells
-
Crossveinless-2 Is a BMP feedback inhibitor that binds Chordin/BMP to regulate Xenopus embryonic patterning. Dev Cell. 2008 Aug; 15(2):248-60.
Ambrosio AL, Taelman VF, Lee HX, Metzinger CA, Coffinier C, De Robertis EM. PMID: 18694564; PMCID: PMC2581521.
View in:
PubMed Mentions:
55 Fields:
Translation:
HumansAnimalsCells
-
Integrating positional information at the level of Smad1/5/8. Curr Opin Genet Dev. 2008 Aug; 18(4):304-10.
Eivers E, Fuentealba LC, De Robertis EM. PMID: 18590818; PMCID: PMC3033225.
View in:
PubMed Mentions:
41 Fields:
Translation:
HumansAnimalsCells
-
Asymmetric mitosis: Unequal segregation of proteins destined for degradation. Proc Natl Acad Sci U S A. 2008 Jun 03; 105(22):7732-7.
Fuentealba LC, Eivers E, Geissert D, Taelman V, De Robertis EM. PMID: 18511557; PMCID: PMC2402384.
View in:
PubMed Mentions:
82 Fields:
Translation:
HumansAnimalsCells
-
Eddy M. De Robertis. Curr Biol. 2008 Apr 22; 18(8):R318-20.
De Robertis EM. PMID: 18561377; PMCID: PMC2606973.
View in:
PubMed Mentions: Fields:
Translation:
Animals
-
Evo-devo: variations on ancestral themes. Cell. 2008 Jan 25; 132(2):185-95.
De Robertis EM. PMID: 18243095; PMCID: PMC2280037.
View in:
PubMed Mentions:
123 Fields:
Translation:
AnimalsCells
-
Integrating patterning signals: Wnt/GSK3 regulates the duration of the BMP/Smad1 signal. Cell. 2007 Nov 30; 131(5):980-93.
Fuentealba LC, Eivers E, Ikeda A, Hurtado C, Kuroda H, Pera EM, De Robertis EM. PMID: 18045539; PMCID: PMC2200633.
View in:
PubMed Mentions:
258 Fields:
Translation:
HumansAnimalsCells
-
Activity-induced protocadherin arcadlin regulates dendritic spine number by triggering N-cadherin endocytosis via TAO2beta and p38 MAP kinases. Neuron. 2007 Nov 08; 56(3):456-71.
Yasuda S, Tanaka H, Sugiura H, Okamura K, Sakaguchi T, Tran U, Takemiya T, Mizoguchi A, Yagita Y, Sakurai T, De Robertis EM, Yamagata K. PMID: 17988630; PMCID: PMC2424284.
View in:
PubMed Mentions:
95 Fields:
Translation:
HumansAnimalsCells
-
Expression of Siamois and Twin in the blastula Chordin/Noggin signaling center is required for brain formation in Xenopus laevis embryos. Mech Dev. 2008; 125(1-2):58-66.
Ishibashi H, Matsumura N, Hanafusa H, Matsumoto K, De Robertis EM, Kuroda H. PMID: 18036787; PMCID: PMC2292103.
View in:
PubMed Mentions:
20 Fields:
Translation:
AnimalsCells
-
The opposing homeobox genes Goosecoid and Vent1/2 self-regulate Xenopus patterning. EMBO J. 2007 Jun 20; 26(12):2955-65.
Sander V, Reversade B, De Robertis EM. PMID: 17525737; PMCID: PMC1894760.
View in:
PubMed Mentions:
48 Fields:
Translation:
AnimalsCells
-
Neural induction in the absence of organizer in salamanders is mediated by MAPK. Dev Biol. 2007 Jul 15; 307(2):282-9.
Hurtado C, De Robertis EM. PMID: 17540356; PMCID: PMC2096472.
View in:
PubMed Mentions:
12 Fields:
Translation:
AnimalsCells
-
Systems biology of embryonic morphogens. Mol Biosyst. 2007 Jul; 3(7):454-7.
Plouhinec JL, De Robertis EM. PMID: 17579769; PMCID: PMC2412835.
View in:
PubMed Mentions:
3 Fields:
Translation:
Animals
-
Spemann's organizer and self-regulation in amphibian embryos. Nat Rev Mol Cell Biol. 2006 Apr; 7(4):296-302.
De Robertis EM. PMID: 16482093; PMCID: PMC2464568.
View in:
PubMed Mentions:
99 Fields:
Translation:
Animals
-
Embryonic dorsal-ventral signaling: secreted frizzled-related proteins as inhibitors of tolloid proteinases. Cell. 2006 Jan 13; 124(1):147-59.
Lee HX, Ambrosio AL, Reversade B, De Robertis EM. PMID: 16413488; PMCID: PMC2486255.
View in:
PubMed Mentions:
102 Fields:
Translation:
AnimalsCells
-
Regulation of ADMP and BMP2/4/7 at opposite embryonic poles generates a self-regulating morphogenetic field. Cell. 2005 Dec 16; 123(6):1147-60.
Reversade B, De Robertis EM. PMID: 16360041; PMCID: PMC2292129.
View in:
PubMed Mentions:
117 Fields:
Translation:
AnimalsCells
-
xBtg-x regulates Wnt/beta-Catenin signaling during early Xenopus development. Dev Biol. 2005 Jul 01; 283(1):17-28.
Wessely O, Kim JI, Tran U, Fuentealba L, De Robertis EM. PMID: 15975429; PMCID: PMC2278116.
View in:
PubMed Mentions:
5 Fields:
Translation:
HumansAnimalsCells
-
Depletion of Bmp2, Bmp4, Bmp7 and Spemann organizer signals induces massive brain formation in Xenopus embryos. Development. 2005 Aug; 132(15):3381-92.
Reversade B, Kuroda H, Lee H, Mays A, De Robertis EM. PMID: 15975940; PMCID: PMC2278118.
View in:
PubMed Mentions:
55 Fields:
Translation:
AnimalsCells
-
Default neural induction: neuralization of dissociated Xenopus cells is mediated by Ras/MAPK activation. Genes Dev. 2005 May 01; 19(9):1022-7.
Kuroda H, Fuentealba L, Ikeda A, Reversade B, De Robertis EM. PMID: 15879552; PMCID: PMC1091736.
View in:
PubMed Mentions:
57 Fields:
Translation:
AnimalsCells
-
Sirenomelia in Bmp7 and Tsg compound mutant mice: requirement for Bmp signaling in the development of ventral posterior mesoderm. Development. 2005 May; 132(10):2489-99.
Zakin L, Reversade B, Kuroda H, Lyons KM, De Robertis EM. PMID: 15843411.
View in:
PubMed Mentions:
28 Fields:
Translation:
AnimalsCells
-
Exploration of the extracellular space by a large-scale secretion screen in the early Xenopus embryo. Int J Dev Biol. 2005; 49(7):781-96.
Pera EM, Hou S, Strate I, Wessely O, De Robertis EM. PMID: 16172975.
View in:
PubMed Mentions:
4 Fields:
Translation:
HumansAnimalsCells
-
Paraxial protocadherin coordinates cell polarity during convergent extension via Rho A and JNK. EMBO J. 2004 Aug 18; 23(16):3259-69.
Unterseher F, Hefele JA, Giehl K, De Robertis EM, Wedlich D, Schambony A. PMID: 15297873; PMCID: PMC514506.
View in:
PubMed Mentions:
61 Fields:
Translation:
AnimalsCells
-
Analysis of Spemann organizer formation in Xenopus embryos by cDNA macroarrays. Dev Biol. 2004 May 15; 269(2):552-66.
Wessely O, Kim JI, Geissert D, Tran U, De Robertis EM. PMID: 15110719.
View in:
PubMed Mentions:
21 Fields:
Translation:
AnimalsCells
-
Neural induction in Xenopus: requirement for ectodermal and endomesodermal signals via Chordin, Noggin, beta-Catenin, and Cerberus. PLoS Biol. 2004 May; 2(5):E92.
Kuroda H, Wessely O, De Robertis EM. PMID: 15138495; PMCID: PMC406387.
View in:
PubMed Mentions:
67 Fields:
Translation:
AnimalsCells
-
Identification of a second Xenopus twisted gastrulation gene. Int J Dev Biol. 2004 Feb; 48(1):57-61.
Oelgeschläger M, Tran U, Grubisic K, De Robertis EM. PMID: 15005575; PMCID: PMC2311381.
View in:
PubMed Mentions:
4 Fields:
Translation:
AnimalsCells
-
Dorsal-ventral patterning and neural induction in Xenopus embryos. Annu Rev Cell Dev Biol. 2004; 20:285-308.
De Robertis EM, Kuroda H. PMID: 15473842; PMCID: PMC2280069.
View in:
PubMed Mentions:
246 Fields:
Translation:
AnimalsCells
-
Inactivation of mouse Twisted gastrulation reveals its role in promoting Bmp4 activity during forebrain development. Development. 2004 Jan; 131(2):413-24.
Zakin L, De Robertis EM. PMID: 14681194.
View in:
PubMed Mentions:
30 Fields:
Translation:
AnimalsCells
-
Integration of IGF, FGF, and anti-BMP signals via Smad1 phosphorylation in neural induction. Genes Dev. 2003 Dec 15; 17(24):3023-8.
Pera EM, Ikeda A, Eivers E, De Robertis EM. PMID: 14701872; PMCID: PMC305254.
View in:
PubMed Mentions:
154 Fields:
Translation:
AnimalsCells
-
The pro-BMP activity of Twisted gastrulation is independent of BMP binding. Development. 2003 Sep; 130(17):4047-56.
Oelgeschläger M, Reversade B, Larraín J, Little S, Mullins MC, De Robertis EM. PMID: 12874126; PMCID: PMC2277362.
View in:
PubMed Mentions:
27 Fields:
Translation:
AnimalsCells
-
The role of chordin/Bmp signals in mammalian pharyngeal development and DiGeorge syndrome. Development. 2003 Aug; 130(15):3567-78.
Bachiller D, Klingensmith J, Shneyder N, Tran U, Anderson R, Rossant J, De Robertis EM. PMID: 12810603.
View in:
PubMed Mentions:
64 Fields:
Translation:
Animals
-
Integrin-alpha3 mediates binding of Chordin to the cell surface and promotes its endocytosis. EMBO Rep. 2003 Aug; 4(8):813-8.
Larraín J, Brown C, De Robertis EM. PMID: 12897802; PMCID: PMC1326342.
View in:
PubMed Mentions:
6 Fields:
Translation:
AnimalsCells
-
Darmin is a novel secreted protein expressed during endoderm development in Xenopus. Gene Expr Patterns. 2003 May; 3(2):147-52.
Pera EM, Martinez SL, Flanagan JJ, Brechner M, Wessely O, De Robertis EM. PMID: 12711541.
View in:
PubMed Mentions:
7 Fields:
Translation:
AnimalsCells
-
Chordin is required for the Spemann organizer transplantation phenomenon in Xenopus embryos. Dev Cell. 2003 Feb; 4(2):219-30.
Oelgeschläger M, Kuroda H, Reversade B, De Robertis EM. PMID: 12586065.
View in:
PubMed Mentions:
58 Fields:
Translation:
Animals
-
Mouse Crossveinless-2 is the vertebrate homolog of a Drosophila extracellular regulator of BMP signaling. Gene Expr Patterns. 2002 Dec; 2(3-4):189-94.
Coffinier C, Ketpura N, Tran U, Geissert D, De Robertis EM. PMID: 12617799.
View in:
PubMed Mentions:
4 Fields:
Translation:
HumansAnimalsCells
-
Mouse Crossveinless-2 is the vertebrate homolog of a Drosophila extracellular regulator of BMP signaling. Mech Dev. 2002 Dec; 119 Suppl 1(Suppl 1):S179-84.
Coffinier C, Ketpura N, Tran U, Geissert D, De Robertis EM. PMID: 14516682; PMCID: PMC3039546.
View in:
PubMed Mentions:
22 Fields:
Translation:
HumansAnimalsCells
-
Connective-tissue growth factor (CTGF) modulates cell signalling by BMP and TGF-beta. Nat Cell Biol. 2002 Aug; 4(8):599-604.
Abreu JG, Ketpura NI, Reversade B, De Robertis EM. PMID: 12134160; PMCID: PMC2387275.
View in:
PubMed Mentions:
349 Fields:
Translation:
AnimalsCells
-
Isthmin is a novel secreted protein expressed as part of the Fgf-8 synexpression group in the Xenopus midbrain-hindbrain organizer. Mech Dev. 2002 Aug; 116(1-2):169-72.
Pera EM, Kim JI, Martinez SL, Brechner M, Li SY, Wessely O, De Robertis EM. PMID: 12128218.
View in:
PubMed Mentions:
31 Fields:
Translation:
HumansAnimalsCells
-
Chordin-like CR domains and the regulation of evolutionarily conserved extracellular signaling systems. Gene. 2002 Apr 03; 287(1-2):39-47.
Garcia Abreu J, Coffinier C, Larraín J, Oelgeschläger M, De Robertis EM. PMID: 11992721.
View in:
PubMed Mentions:
60 Fields:
Translation:
HumansAnimalsCells
-
Neural plate patterning by secreted signals. Neuron. 2002 Feb 14; 33(4):489-91.
Wessely O, De Robertis EM. PMID: 11856521; PMCID: PMC3039547.
View in:
PubMed Mentions:
8 Fields:
Translation:
HumansAnimalsCells
-
Proteolytic cleavage of Chordin as a switch for the dual activities of Twisted gastrulation in BMP signaling. Development. 2001 Nov; 128(22):4439-47.
Larraín J, Oelgeschläger M, Ketpura NI, Reversade B, Zakin L, De Robertis EM. PMID: 11714670; PMCID: PMC2277371.
View in:
PubMed Mentions:
63 Fields:
Translation:
AnimalsCells
-
Neural and head induction by insulin-like growth factor signals. Dev Cell. 2001 Nov; 1(5):655-65.
Pera EM, Wessely O, Li SY, De Robertis EM. PMID: 11709186.
View in:
PubMed Mentions:
71 Fields:
Translation:
HumansAnimalsCells
-
New twists on embryonic patterning. EMBO workshop: embryonic organizer signaling: the next frontiers. EMBO Rep. 2001 Aug; 2(8):661-5.
De Robertis EM, Bouwmeester T. PMID: 11493592; PMCID: PMC1084000.
View in:
PubMed Mentions: Fields:
Translation:
AnimalsCells
-
Neural induction in the absence of mesoderm: beta-catenin-dependent expression of secreted BMP antagonists at the blastula stage in Xenopus. Dev Biol. 2001 Jun 01; 234(1):161-73.
Wessely O, Agius E, Oelgeschläger M, Pera EM, De Robertis EM. PMID: 11356027; PMCID: PMC3039525.
View in:
PubMed Mentions:
34 Fields:
Translation:
AnimalsCells
-
Identification and expression of the mammalian homologue of Bicaudal-C. Mech Dev. 2001 Mar; 101(1-2):267-70.
Wessely O, Tran U, Zakin L, De Robertis EM. PMID: 11231089.
View in:
PubMed Mentions:
11 Fields:
Translation:
HumansAnimalsCells
-
Molecular mechanisms of cell-cell signaling by the Spemann-Mangold organizer. Int J Dev Biol. 2001; 45(1):189-97.
De Robertis EM, Wessely O, Oelgeschläger M, Brizuela B, Pera E, Larraín J, Abreu J, Bachiller D. PMID: 11291846; PMCID: PMC2354921.
View in:
PubMed Mentions:
17 Fields:
Translation:
AnimalsCells
-
The establishment of Spemann's organizer and patterning of the vertebrate embryo. Nat Rev Genet. 2000 Dec; 1(3):171-81.
De Robertis EM, Larraín J, Oelgeschläger M, Wessely O. PMID: 11252746; PMCID: PMC2291143.
View in:
PubMed Mentions:
115 Fields:
Translation:
AnimalsCells