Heather R Christofk

Title(s)Professor, Biological Chemistry
SchoolMedicine
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    Collapse Research 
    Collapse Research Activities and Funding
    Metabolic Control of Hair Follicle Stem Cell Homeostasis and Tumorigenesis
    NIH R01AR070245Mar 12, 2018 - Feb 28, 2023
    Role: Co-Principal Investigator
    Nutrient regulation of cancer cell growth
    NIH R01CA215185Dec 6, 2017 - Nov 30, 2022
    Role: Principal Investigator
    Regulation of the Warburg Effect in Cancer
    NIH DP2OD008454Sep 30, 2011 - Jun 30, 2016
    Role: Principal Investigator

    Collapse Bibliographic 
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Endothelial Jagged1 levels and distribution are post-transcriptionally controlled by ZFP36 decay proteins. Cell Rep. 2024 01 23; 43(1):113627. Sunshine HL, Cicchetto AC, Kaczor-Urbanowicz KE, Ma F, Pi D, Symons C, Turner M, Shukla V, Christofk HR, Vallim TA, Iruela-Arispe ML. PMID: 38157296; PMCID: PMC10884959.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    2. Atlas of fetal metabolism during mid-to-late gestation and diabetic pregnancy. Cell. 2024 01 04; 187(1):204-215.e14. Perez-Ramirez CA, Nakano H, Law RC, Matulionis N, Thompson J, Pfeiffer A, Park JO, Nakano A, Christofk HR. PMID: 38070508; PMCID: PMC10843853.
      View in: PubMed   Mentions: 2     Fields:    Translation:Animals
    3. Defining metabolic flexibility in hair follicle stem cell induced squamous cell carcinoma. bioRxiv. 2023 Oct 19. Galvan C, Flores A, Cerrillos V, Avila I, Murphy C, Zheng W, To TT, Christofk HR, Lowry WE. PMID: 37905122; PMCID: PMC10614763.
      View in: PubMed   Mentions:
    4. MYC is a regulator of androgen receptor inhibition-induced metabolic requirements in prostate cancer. Cell Rep. 2023 10 31; 42(10):113221. Crowell PD, Giafaglione JM, Jones AE, Nunley NM, Hashimoto T, Delcourt AML, Petcherski A, Agrawal R, Bernard MJ, Diaz JA, Heering KY, Huang RR, Low JY, Matulionis N, Navone NM, Ye H, Zoubeidi A, Christofk HR, Rettig MB, Reiter RE, Haffner MC, Boutros PC, Shirihai OS, Divakaruni AS, Goldstein AS. PMID: 37815914.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    5. Vitamin B6 is governed by the local compartmentalization of metabolic enzymes during growth. Sci Adv. 2023 09 08; 9(36):eadi2232. Franco CN, Seabrook LJ, Nguyen ST, Yang Y, Campos M, Fan Q, Cicchetto AC, Kong M, Christofk HR, Albrecht LV. PMID: 37682999; PMCID: PMC10491294.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    6. FH Variant Pathogenicity Promotes Purine Salvage Pathway Dependence in Kidney Cancer. Cancer Discov. 2023 09 06; 13(9):2072-2089. Wilde BR, Chakraborty N, Matulionis N, Hernandez S, Ueno D, Gee ME, Esplin ED, Ouyang K, Nykamp K, Shuch B, Christofk HR. PMID: 37255402; PMCID: PMC10527600.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    7. Acute activation of adipocyte lipolysis reveals dynamic lipid remodeling of the hepatic lipidome. J Lipid Res. 2024 Feb; 65(2):100434. Zhang S, Williams KJ, Verlande-Ferrero A, Chan AP, Su GB, Kershaw EE, Cox JE, Maschek JA, Shapira SN, Christofk HR, de Aguiar Vallim TQ, Masri S, Villanueva CJ. PMID: 37640283; PMCID: PMC10839691.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    8. Nutrient regulation of development and cell fate decisions. Development. 2023 10 15; 150(20). Tu WB, Christofk HR, Plath K. PMID: 37260407; PMCID: PMC10281554.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    9. ZFP36-mediated mRNA decay regulates metabolism. Cell Rep. 2023 05 30; 42(5):112411. Cicchetto AC, Jacobson EC, Sunshine H, Wilde BR, Krall AS, Jarrett KE, Sedgeman L, Turner M, Plath K, Iruela-Arispe ML, de Aguiar Vallim TQ, Christofk HR. PMID: 37086408; PMCID: PMC10332406.
      View in: PubMed   Mentions: 2     Fields:    Translation:Cells
    10. Fumarate Hydratase Variants and Their Association With Paraganglioma/Pheochromocytoma. Urology. 2023 Jun; 176:106-114. Zavoshi S, Lu E, Boutros PC, Zhang L, Harari A, Hatchell KE, Nielsen SM, Esplin ED, Ouyang K, Nykamp K, Wilde B, Christofk H, Shuch B. PMID: 36773955.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    11. Differential integrated stress response and asparagine production drive symbiosis and therapy resistance of pancreatic adenocarcinoma cells. Nat Cancer. 2022 11; 3(11):1386-1403. Halbrook CJ, Thurston G, Boyer S, Anaraki C, Jiménez JA, McCarthy A, Steele NG, Kerk SA, Hong HS, Lin L, Law FV, Felton C, Scipioni L, Sajjakulnukit P, Andren A, Beutel AK, Singh R, Nelson BS, Van Den Bergh F, Krall AS, Mullen PJ, Zhang L, Batra S, Morton JP, Stanger BZ, Christofk HR, Digman MA, Beard DA, Viale A, Zhang J, Crawford HC, Pasca di Magliano M, Jorgensen C, Lyssiotis CA. PMID: 36411320; PMCID: PMC9701142.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansAnimals
    12. TGFβ superfamily signaling regulates the state of human stem cell pluripotency and capacity to create well-structured telencephalic organoids. Stem Cell Reports. 2022 10 11; 17(10):2220-2238. Watanabe M, Buth JE, Haney JR, Vishlaghi N, Turcios F, Elahi LS, Gu W, Pearson CA, Kurdian A, Baliaouri NV, Collier AJ, Miranda OA, Dunn N, Chen D, Sabri S, Torre-Ubieta L, Clark AT, Plath K, Christofk HR, Kornblum HI, Gandal MJ, Novitch BG. PMID: 36179695; PMCID: PMC9561534.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCells
    13. A pathogenic role for histone H3 copper reductase activity in a yeast model of Friedreich's ataxia. Sci Adv. 2021 Dec 17; 7(51):eabj9889. Campos OA, Attar N, Cheng C, Vogelauer M, Mallipeddi NV, Schmollinger S, Matulionis N, Christofk HR, Merchant SS, Kurdistani SK. PMID: 34919435; PMCID: PMC8682991.
      View in: PubMed   Mentions: 1     Fields:    
    14. Fumarate hydratase variant prevalence and manifestations among individuals receiving germline testing. Cancer. 2022 02 15; 128(4):675-684. Lu E, Hatchell KE, Nielsen SM, Esplin ED, Ouyang K, Nykamp K, Zavoshi S, Li S, Zhang L, Wilde BR, Christofk HR, Boutros PC, Shuch B. PMID: 34724198; PMCID: PMC9170268.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
    15. More Metabolism! Mol Cell. 2021 09 16; 81(18):3659-3664. Olzmann JA, Fendt SM, Shah YM, Vousden K, Chandel N, Horng T, Danial N, Tu B, Christofk H, Vander Heiden MG, Wellen K. PMID: 34547228.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    16. Metabolic decisions in development and disease-a Keystone Symposia report. Ann N Y Acad Sci. 2021 12; 1506(1):55-73. Cable J, Pourquié O, Wellen KE, Finley LWS, Aulehla A, Gould AP, Teleman A, Tu WB, Garrett WS, Miguel-Aliaga I, Perrimon N, Hooper LV, Walhout AJM, Wei W, Alexandrov T, Erez A, Ralser M, Rabinowitz JD, Hemalatha A, Gutiérrez-Pérez P, Chandel NS, Rutter J, Locasale JW, Landoni JC, Christofk H. PMID: 34414571.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimalsCells
    17. Monocarboxylate transporter antagonism reveals metabolic vulnerabilities of viral-driven lymphomas. Proc Natl Acad Sci U S A. 2021 06 22; 118(25). Bonglack EN, Messinger JE, Cable JM, Ch'ng J, Parnell KM, Reinoso-Vizcaíno NM, Barry AP, Russell VS, Dave SS, Christofk HR, Luftig MA. PMID: 34161263; PMCID: PMC8237662.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansCells
    18. Targeting nucleotide metabolism as the nexus of viral infections, cancer, and the immune response. Sci Adv. 2021 05; 7(21). Ariav Y, Ch'ng JH, Christofk HR, Ron-Harel N, Erez A. PMID: 34138729; PMCID: PMC8133749.
      View in: PubMed   Mentions: 23     Fields:    Translation:Humans
    19. GLUT1 overexpression enhances glucose metabolism and promotes neonatal heart regeneration. Sci Rep. 2021 04 21; 11(1):8669. Fajardo VM, Feng I, Chen BY, Perez-Ramirez CA, Shi B, Clark P, Tian R, Lien CL, Pellegrini M, Christofk H, Nakano H, Nakano A. PMID: 33883682; PMCID: PMC8060418.
      View in: PubMed   Mentions: 18     Fields:    Translation:AnimalsCells
    20. SARS-CoV-2 infection rewires host cell metabolism and is potentially susceptible to mTORC1 inhibition. Nat Commun. 2021 03 25; 12(1):1876. Mullen PJ, Garcia G, Purkayastha A, Matulionis N, Schmid EW, Momcilovic M, Sen C, Langerman J, Ramaiah A, Shackelford DB, Damoiseaux R, French SW, Plath K, Gomperts BN, Arumugaswami V, Christofk HR. PMID: 33767183; PMCID: PMC7994801.
      View in: PubMed   Mentions: 60     Fields:    Translation:HumansAnimalsCells
    21. Challenges in Studying Stem Cell Metabolism. Cell Stem Cell. 2021 03 04; 28(3):409-423. Perez-Ramirez CA, Christofk HR. PMID: 33667361.
      View in: PubMed   Mentions: 7     Fields:    Translation:Cells
    22. Asparagine couples mitochondrial respiration to ATF4 activity and tumor growth. Cell Metab. 2021 05 04; 33(5):1013-1026.e6. Krall AS, Mullen PJ, Surjono F, Momcilovic M, Schmid EW, Halbrook CJ, Thambundit A, Mittelman SD, Lyssiotis CA, Shackelford DB, Knott SRV, Christofk HR. PMID: 33609439; PMCID: PMC8102379.
      View in: PubMed   Mentions: 78     Fields:    Translation:HumansAnimalsCells
    23. Development of Novel Mitochondrial Pyruvate Carrier Inhibitors to Treat Hair Loss. J Med Chem. 2021 02 25; 64(4):2046-2063. Liu X, Flores AA, Situ L, Gu W, Ding H, Christofk HR, Lowry WE, Jung ME. PMID: 33534563; PMCID: PMC8939290.
      View in: PubMed   Mentions: 7     Fields:    Translation:AnimalsCells
    24. O-Mg! Lactate Drives Mg2+ Mobilization. Mol Cell. 2020 12 03; 80(5):762-763. Wilde BR, Christofk HR. PMID: 33275887.
      View in: PubMed   Mentions:    Fields:    Translation:Cells
    25. Glioblastoma Utilizes Fatty Acids and Ketone Bodies for Growth Allowing Progression during Ketogenic Diet Therapy. iScience. 2020 Sep 25; 23(9):101453. Sperry J, Condro MC, Guo L, Braas D, Vanderveer-Harris N, Kim KKO, Pope WB, Divakaruni AS, Lai A, Christofk H, Castro MG, Lowenstein PR, Le Belle JE, Kornblum HI. PMID: 32861192; PMCID: PMC7471621.
      View in: PubMed   Mentions: 34  
    26. GSK3 Inhibits Macropinocytosis and Lysosomal Activity through the Wnt Destruction Complex Machinery. Cell Rep. 2020 07 28; 32(4):107973. Albrecht LV, Tejeda-Muñoz N, Bui MH, Cicchetto AC, Di Biagio D, Colozza G, Schmid E, Piccolo S, Christofk HR, De Robertis EM. PMID: 32726636; PMCID: PMC7666578.
      View in: PubMed   Mentions: 28     Fields:    Translation:AnimalsCells
    27. Metabolic Regulation of Tissue Stem Cells. Trends Cell Biol. 2020 07; 30(7):566-576. Shapira SN, Christofk HR. PMID: 32359707; PMCID: PMC8059102.
      View in: PubMed   Mentions: 21     Fields:    Translation:HumansAnimalsCells
    28. Publisher Correction: In vivo imaging of mitochondrial membrane potential in non-small-cell lung cancer. Nature. 2020 01; 577(7791):E7. Momcilovic M, Jones A, Bailey ST, Waldmann CM, Li R, Lee JT, Abdelhady G, Gomez A, Holloway T, Schmid E, Stout D, Fishbein MC, Stiles L, Dabir DV, Dubinett SM, Christofk H, Shirihai O, Koehler CM, Sadeghi S, Shackelford DB. PMID: 31896820.
      View in: PubMed   Mentions:    Fields:    
    29. In vivo imaging of mitochondrial membrane potential in non-small-cell lung cancer. Nature. 2019 11; 575(7782):380-384. Momcilovic M, Jones A, Bailey ST, Waldmann CM, Li R, Lee JT, Abdelhady G, Gomez A, Holloway T, Schmid E, Stout D, Fishbein MC, Stiles L, Dabir DV, Dubinett SM, Christofk H, Shirihai O, Koehler CM, Sadeghi S, Shackelford DB. PMID: 31666695; PMCID: PMC7328016.
      View in: PubMed   Mentions: 86     Fields:    Translation:HumansAnimalsCells
    30. Viral hijacking of cellular metabolism. BMC Biol. 2019 07 18; 17(1):59. Thaker SK, Ch'ng J, Christofk HR. PMID: 31319842; PMCID: PMC6637495.
      View in: PubMed   Mentions: 196     Fields:    Translation:Cells
    31. Author Correction: Increased lactate dehydrogenase activity is dispensable in squamous carcinoma cells of origin. Nat Commun. 2019 03 26; 10(1):1449. Flores A, Sandoval-Gonzalez S, Takahashi R, Krall A, Sathe L, Wei L, Radu C, Joly JH, Graham NA, Christofk HR, Lowry WE. PMID: 30914644; PMCID: PMC6435690.
      View in: PubMed   Mentions:    Fields:    
    32. Differential Metabolic Reprogramming by Zika Virus Promotes Cell Death in Human versus Mosquito Cells. Cell Metab. 2019 05 07; 29(5):1206-1216.e4. Thaker SK, Chapa T, Garcia G, Gong D, Schmid EW, Arumugaswami V, Sun R, Christofk HR. PMID: 30827860; PMCID: PMC6818653.
      View in: PubMed   Mentions: 41     Fields:    Translation:HumansAnimalsCells
    33. Increased lactate dehydrogenase activity is dispensable in squamous carcinoma cells of origin. Nat Commun. 2019 01 09; 10(1):91. Flores A, Sandoval-Gonzalez S, Takahashi R, Krall A, Sathe L, Wei L, Radu C, Joly JH, Graham NA, Christofk HR, Lowry WE. PMID: 30626875; PMCID: PMC6327029.
      View in: PubMed   Mentions: 19     Fields:    Translation:Animals
    34. The next decade of metabolism. Nat Metab. 2019 01; 1(1):2-4. Bäckhed F, Bugianesi E, Christofk H, Dikic I, Gupta R, Mair WB, O'Neill LAJ, Ralser M, Sabatini DM, Tschöp M. PMID: 32694817.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimals
    35. Extracellular Matrix Remodeling Regulates Glucose Metabolism through TXNIP Destabilization. Cell. 2018 09 20; 175(1):117-132.e21. Sullivan WJ, Mullen PJ, Schmid EW, Flores A, Momcilovic M, Sharpley MS, Jelinek D, Whiteley AE, Maxwell MB, Wilde BR, Banerjee U, Coller HA, Shackelford DB, Braas D, Ayer DE, de Aguiar Vallim TQ, Lowry WE, Christofk HR. PMID: 30197082; PMCID: PMC6151140.
      View in: PubMed   Mentions: 111     Fields:    Translation:HumansCells
    36. Mapping Metabolism: Monitoring Lactate Dehydrogenase Activity Directly in Tissue. J Vis Exp. 2018 06 21; (136). Jelinek D, Flores A, Uebelhoer M, Pasque V, Plath K, Iruela-Arispe ML, Christofk HR, Lowry WE, Coller HA. PMID: 29985359; PMCID: PMC6101961.
      View in: PubMed   Mentions: 5     Fields:    Translation:Animals
    37. The GSK3 Signaling Axis Regulates Adaptive Glutamine Metabolism in Lung Squamous Cell Carcinoma. Cancer Cell. 2018 05 14; 33(5):905-921.e5. Momcilovic M, Bailey ST, Lee JT, Fishbein MC, Braas D, Go J, Graeber TG, Parlati F, Demo S, Li R, Walser TC, Gricowski M, Shuman R, Ibarra J, Fridman D, Phelps ME, Badran K, St John M, Bernthal NM, Federman N, Yanagawa J, Dubinett SM, Sadeghi S, Christofk HR, Shackelford DB. PMID: 29763624; PMCID: PMC6451645.
      View in: PubMed   Mentions: 85     Fields:    Translation:HumansAnimalsCells
    38. Metabolic characterization of isocitrate dehydrogenase (IDH) mutant and IDH wildtype gliomaspheres uncovers cell type-specific vulnerabilities. Cancer Metab. 2018; 6:4. Garrett M, Sperry J, Braas D, Yan W, Le TM, Mottahedeh J, Ludwig K, Eskin A, Qin Y, Levy R, Breunig JJ, Pajonk F, Graeber TG, Radu CG, Christofk H, Prins RM, Lai A, Liau LM, Coppola G, Kornblum HI. PMID: 29692895; PMCID: PMC5905129.
      View in: PubMed   Mentions: 34  
    39. Glucose inhibits cardiac muscle maturation through nucleotide biosynthesis. Elife. 2017 12 12; 6. Nakano H, Minami I, Braas D, Pappoe H, Wu X, Sagadevan A, Vergnes L, Fu K, Morselli M, Dunham C, Ding X, Stieg AZ, Gimzewski JK, Pellegrini M, Clark PM, Reue K, Lusis AJ, Ribalet B, Kurdistani SK, Christofk H, Nakatsuji N, Nakano A. PMID: 29231167; PMCID: PMC5726851.
      View in: PubMed   Mentions: 84     Fields:    Translation:HumansAnimalsCells
    40. Topical Inhibition of the Electron Transport Chain Can Stimulate the Hair Cycle. J Invest Dermatol. 2018 04; 138(4):968-972. Miranda M, Christofk H, Jones DL, Lowry WE. PMID: 29106930; PMCID: PMC8966693.
      View in: PubMed   Mentions: 4     Fields:    Translation:AnimalsCells
    41. Lactate dehydrogenase activity drives hair follicle stem cell activation. Nat Cell Biol. 2017 Sep; 19(9):1017-1026. Flores A, Schell J, Krall AS, Jelinek D, Miranda M, Grigorian M, Braas D, White AC, Zhou JL, Graham NA, Graeber T, Seth P, Evseenko D, Coller HA, Rutter J, Christofk HR, Lowry WE. PMID: 28812580; PMCID: PMC5657543.
      View in: PubMed   Mentions: 106     Fields:    Translation:AnimalsCells
    42. Control of intestinal stem cell function and proliferation by mitochondrial pyruvate metabolism. Nat Cell Biol. 2017 Sep; 19(9):1027-1036. Schell JC, Wisidagama DR, Bensard C, Zhao H, Wei P, Tanner J, Flores A, Mohlman J, Sorensen LK, Earl CS, Olson KA, Miao R, Waller TC, Delker D, Kanth P, Jiang L, DeBerardinis RJ, Bronner MP, Li DY, Cox JE, Christofk HR, Lowry WE, Thummel CS, Rutter J. PMID: 28812582; PMCID: PMC6137334.
      View in: PubMed   Mentions: 140     Fields:    Translation:HumansAnimalsCells
    43. mTORC2 Regulates Amino Acid Metabolism in Cancer by Phosphorylation of the Cystine-Glutamate Antiporter xCT. Mol Cell. 2017 Jul 06; 67(1):128-138.e7. Gu Y, Albuquerque CP, Braas D, Zhang W, Villa GR, Bi J, Ikegami S, Masui K, Gini B, Yang H, Gahman TC, Shiau AK, Cloughesy TF, Christofk HR, Zhou H, Guan KL, Mischel PS. PMID: 28648777; PMCID: PMC5521991.
      View in: PubMed   Mentions: 97     Fields:    Translation:HumansCells
    44. Cell cycle: Division enzyme regulates metabolism. Nature. 2017 06 15; 546(7658):357-358. Krall AS, Christofk HR. PMID: 28607481.
      View in: PubMed   Mentions: 8     Fields:    
    45. Recurrent patterns of DNA copy number alterations in tumors reflect metabolic selection pressures. Mol Syst Biol. 2017 02 15; 13(2):914. Graham NA, Minasyan A, Lomova A, Cass A, Balanis NG, Friedman M, Chan S, Zhao S, Delgado A, Go J, Beck L, Hurtz C, Ng C, Qiao R, Ten Hoeve J, Palaskas N, Wu H, Müschen M, Multani AS, Port E, Larson SM, Schultz N, Braas D, Christofk HR, Mellinghoff IK, Graeber TG. PMID: 28202506; PMCID: PMC5327725.
      View in: PubMed   Mentions: 39     Fields:    Translation:HumansCells
    46. Targeted Inhibition of EGFR and Glutaminase Induces Metabolic Crisis in EGFR Mutant Lung Cancer. Cell Rep. 2017 01 17; 18(3):601-610. Momcilovic M, Bailey ST, Lee JT, Fishbein MC, Magyar C, Braas D, Graeber T, Jackson NJ, Czernin J, Emberley E, Gross M, Janes J, Mackinnon A, Pan A, Rodriguez M, Works M, Zhang W, Parlati F, Demo S, Garon E, Krysan K, Walser TC, Dubinett SM, Sadeghi S, Christofk HR, Shackelford DB. PMID: 28099841; PMCID: PMC5260616.
      View in: PubMed   Mentions: 78     Fields:    Translation:HumansAnimalsCells
    47. Glycolytic Metabolism Plays a Functional Role in Regulating Human Pluripotent Stem Cell State. Cell Stem Cell. 2016 10 06; 19(4):476-490. Gu W, Gaeta X, Sahakyan A, Chan AB, Hong CS, Kim R, Braas D, Plath K, Lowry WE, Christofk HR. PMID: 27618217; PMCID: PMC5055460.
      View in: PubMed   Mentions: 136     Fields:    Translation:HumansAnimalsCells
    48. Epigenetic changes mediated by polycomb repressive complex 2 and E2a are associated with drug resistance in a mouse model of lymphoma. Genome Med. 2016 05 04; 8(1):54. Flinders C, Lam L, Rubbi L, Ferrari R, Fitz-Gibbon S, Chen PY, Thompson M, Christofk H, B Agus D, Ruderman D, Mallick P, Pellegrini M. PMID: 27146673; PMCID: PMC4857420.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansAnimalsCells
    49. Asparagine promotes cancer cell proliferation through use as an amino acid exchange factor. Nat Commun. 2016 Apr 29; 7:11457. Krall AS, Xu S, Graeber TG, Braas D, Christofk HR. PMID: 27126896; PMCID: PMC4855534.
      View in: PubMed   Mentions: 236     Fields:    Translation:HumansCells
    50. MCT1 Modulates Cancer Cell Pyruvate Export and Growth of Tumors that Co-express MCT1 and MCT4. Cell Rep. 2016 Feb 23; 14(7):1590-1601. Hong CS, Graham NA, Gu W, Espindola Camacho C, Mah V, Maresh EL, Alavi M, Bagryanova L, Krotee PAL, Gardner BK, Behbahan IS, Horvath S, Chia D, Mellinghoff IK, Hurvitz SA, Dubinett SM, Critchlow SE, Kurdistani SK, Goodglick L, Braas D, Graeber TG, Christofk HR. PMID: 26876179; PMCID: PMC4816454.
      View in: PubMed   Mentions: 108     Fields:    Translation:HumansAnimalsCells
    51. Rethinking glutamine addiction. Nat Cell Biol. 2015 Dec; 17(12):1515-7. Krall AS, Christofk HR. PMID: 26612572.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansAnimals
    52. MYC-induced reprogramming of glutamine catabolism supports optimal virus replication. Nat Commun. 2015 Nov 12; 6:8873. Thai M, Thaker SK, Feng J, Du Y, Hu H, Ting Wu T, Graeber TG, Braas D, Christofk HR. PMID: 26561297; PMCID: PMC4660206.
      View in: PubMed   Mentions: 69     Fields:    Translation:HumansCells
    53. 2-Hydroxyglutarate Inhibits ATP Synthase and mTOR Signaling. Cell Metab. 2015 Sep 01; 22(3):508-15. Fu X, Chin RM, Vergnes L, Hwang H, Deng G, Xing Y, Pai MY, Li S, Ta L, Fazlollahi F, Chen C, Prins RM, Teitell MA, Nathanson DA, Lai A, Faull KF, Jiang M, Clarke SG, Cloughesy TF, Graeber TG, Braas D, Christofk HR, Jung ME, Reue K, Huang J. PMID: 26190651; PMCID: PMC4663076.
      View in: PubMed   Mentions: 124     Fields:    Translation:HumansAnimalsCells
    54. Autocrine VEGF maintains endothelial survival through regulation of metabolism and autophagy. J Cell Sci. 2015 Jun 15; 128(12):2236-48. Domigan CK, Warren CM, Antanesian V, Happel K, Ziyad S, Lee S, Krall A, Duan L, Torres-Collado AX, Castellani LW, Elashoff D, Christofk HR, van der Bliek AM, Potente M, Iruela-Arispe ML. PMID: 25956888; PMCID: PMC4487014.
      View in: PubMed   Mentions: 69     Fields:    Translation:HumansAnimalsCells
    55. The metabolic milieu of metastases. Cell. 2015 Jan 29; 160(3):363-4. Sullivan WJ, Christofk HR. PMID: 25635452.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansAnimals
    56. Estrogen receptor (ER)α-regulated lipocalin 2 expression in adipose tissue links obesity with breast cancer progression. J Biol Chem. 2015 Feb 27; 290(9):5566-81. Drew BG, Hamidi H, Zhou Z, Villanueva CJ, Krum SA, Calkin AC, Parks BW, Ribas V, Kalajian NY, Phun J, Daraei P, Christofk HR, Hewitt SC, Korach KS, Tontonoz P, Lusis AJ, Slamon DJ, Hurvitz SA, Hevener AL. PMID: 25468909; PMCID: PMC4342471.
      View in: PubMed   Mentions: 41     Fields:    Translation:HumansAnimalsCells
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