Catherine Freitag Clarke

Title(s)Professor, Chemistry and Biochemistry
SchoolCollege of Letters and Science
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    Collapse Research 
    Collapse Research Activities and Funding
    FASEB Summer Research Conference on Biological Methylation
    NIH R13CA121747Jun 27, 2006 - May 31, 2007
    Role: Principal Investigator
    Coenzyme Q and Aging in Caenorhabditis elegans
    NIH R01AG019777Apr 1, 2002 - Mar 31, 2009
    Role: Principal Investigator
    Coenzyme Q and Aging in Caenorhabditis elegans
    NIH R55AG019777Sep 15, 2001 - Mar 31, 2002
    Role: Principal Investigator
    COENZYME Q AND AGING IN CAENORHABDITIES ELEGANS
    NIH R03AG018085Apr 1, 2000 - Mar 31, 2002
    Role: Principal Investigator
    UCLA Maximizing Student Development (MSD) Program
    NIH R25GM055052Sep 30, 1996 - Feb 28, 2022
    Role: Co-Principal Investigator
    FUNCTIONAL ROLES OF COENZYME Q IN YEAST AND HUMAN CELLS
    NIH R01GM045952Apr 1, 1991 - Nov 30, 2011
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Nonfunctional coq10 mutants maintain the ERMES complex and reveal true phenotypes associated with the loss of the coenzyme Q chaperone protein Coq10. J Biol Chem. 2024 Sep 27; 107820. Novales NA, Feustel KJ, He KL, Chanfreau GF, Clarke CF. PMID: 39343004.
      View in: PubMed   Mentions:    Fields:    
    2. New Insights on the Uptake and Trafficking of Coenzyme Q. Antioxidants (Basel). 2023 Jul 06; 12(7). Guile MD, Jain A, Anderson KA, Clarke CF. PMID: 37507930; PMCID: PMC10376127.
      View in: PubMed   Mentions: 3  
    3. Predicting and Understanding the Pathology of Single Nucleotide Variants in Human COQ Genes. Antioxidants (Basel). 2022 Nov 22; 11(12). Wang S, Jain A, Novales NA, Nashner AN, Tran F, Clarke CF. PMID: 36552517; PMCID: PMC9774615.
      View in: PubMed   Mentions: 3  
    4. Carbonyl Posttranslational Modification Associated With Early-Onset Type 1 Diabetes Autoimmunity. Diabetes. 2022 09 01; 71(9):1979-1993. Yang ML, Connolly SE, Gee RJ, Lam TT, Kanyo J, Peng J, Guyer P, Syed F, Tse HM, Clarke SG, Clarke CF, James EA, Speake C, Evans-Molina C, Arvan P, Herold KC, Wen L, Mamula MJ. PMID: 35730902; PMCID: PMC9450849.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansAnimalsCells
    5. A dedicated flavin-dependent monooxygenase catalyzes the hydroxylation of demethoxyubiquinone into ubiquinone (coenzyme Q) in Arabidopsis. J Biol Chem. 2021 11; 297(5):101283. Latimer S, Keene SA, Stutts LR, Berger A, Bernert AC, Soubeyrand E, Wright J, Clarke CF, Block AK, Colquhoun TA, Elowsky C, Christensen A, Wilson MA, Basset GJ. PMID: 34626646; PMCID: PMC8559556.
      View in: PubMed   Mentions: 7     Fields:    Translation:AnimalsCells
    6. Genetic screening reveals phospholipid metabolism as a key regulator of the biosynthesis of the redox-active lipid coenzyme Q. Redox Biol. 2021 10; 46:102127. Ayer A, Fazakerley DJ, Suarna C, Maghzal GJ, Sheipouri D, Lee KJ, Bradley MC, Fernández-Del-Rio L, Tumanov S, Kong SM, van der Veen JN, Yang A, Ho JWK, Clarke SG, James DE, Dawes IW, Vance DE, Clarke CF, Jacobs RL, Stocker R. PMID: 34521065; PMCID: PMC8435697.
      View in: PubMed   Mentions: 6     Fields:    Translation:AnimalsCells
    7. Regulation of hepatic coenzyme Q biosynthesis by dietary omega-3 polyunsaturated fatty acids. Redox Biol. 2021 10; 46:102061. Fernández-Del-Río L, Rodríguez-López S, Gutiérrez-Casado E, González-Reyes JA, Clarke CF, Burón MI, Villalba JM. PMID: 34246922; PMCID: PMC8274332.
      View in: PubMed   Mentions: 4     Fields:    Translation:AnimalsCells
    8. Coenzyme Q Biosynthesis: An Update on the Origins of the Benzenoid Ring and Discovery of New Ring Precursors. Metabolites. 2021 Jun 14; 11(6). Fernández-Del-Río L, Clarke CF. PMID: 34198496; PMCID: PMC8231959.
      View in: PubMed   Mentions: 13  
    9. The mitochondrial carrier SFXN1 is critical for complex III integrity and cellular metabolism. Cell Rep. 2021 03 16; 34(11):108869. Acoba MG, Alpergin ESS, Renuse S, Fernández-Del-Río L, Lu YW, Khalimonchuk O, Clarke CF, Pandey A, Wolfgang MJ, Claypool SM. PMID: 33730581; PMCID: PMC8048093.
      View in: PubMed   Mentions: 24     Fields:    Translation:HumansCells
    10. Metabolism of the Flavonol Kaempferol in Kidney Cells Liberates the B-ring to Enter Coenzyme Q Biosynthesis. Molecules. 2020 Jun 27; 25(13). Fernández-Del-Río L, Soubeyrand E, Basset GJ, Clarke CF. PMID: 32605010; PMCID: PMC7412559.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansAnimalsCells
    11. Intragenic suppressor mutations of the COQ8 protein kinase homolog restore coenzyme Q biosynthesis and function in Saccharomyces cerevisiae. PLoS One. 2020; 15(6):e0234192. Awad AM, Nag A, Pham NVB, Bradley MC, Jabassini N, Nathaniel J, Clarke CF. PMID: 32479562; PMCID: PMC7263595.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    12. ADCK4 Deficiency Destabilizes the Coenzyme Q Complex, Which Is Rescued by 2,4-Dihydroxybenzoic Acid Treatment. J Am Soc Nephrol. 2020 06; 31(6):1191-1211. Widmeier E, Yu S, Nag A, Chung YW, Nakayama M, Fernández-Del-Río L, Hugo H, Schapiro D, Buerger F, Choi WI, Helmstädter M, Kim JW, Ryu JH, Lee MG, Clarke CF, Hildebrandt F, Gee HY. PMID: 32381600; PMCID: PMC7269352.
      View in: PubMed   Mentions: 30     Fields:    Translation:HumansAnimalsCells
    13. Genes and lipids that impact uptake and assimilation of exogenous coenzyme Q in Saccharomyces cerevisiae. Free Radic Biol Med. 2020 07; 154:105-118. Fernández-Del-Río L, Kelly ME, Contreras J, Bradley MC, James AM, Murphy MP, Payne GS, Clarke CF. PMID: 32387128; PMCID: PMC7611304.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansAnimals
    14. COQ11 deletion mitigates respiratory deficiency caused by mutations in the gene encoding the coenzyme Q chaperone protein Coq10. J Biol Chem. 2020 05 01; 295(18):6023-6042. Bradley MC, Yang K, Fernández-Del-Río L, Ngo J, Ayer A, Tsui HS, Novales NA, Stocker R, Shirihai OS, Barros MH, Clarke CF. PMID: 32205446; PMCID: PMC7196636.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansAnimalsCells
    15. Recombinant RquA catalyzes the in vivo conversion of ubiquinone to rhodoquinone in Escherichia coli and Saccharomyces cerevisiae. Biochim Biophys Acta Mol Cell Biol Lipids. 2019 09; 1864(9):1226-1234. Bernert AC, Jacobs EJ, Reinl SR, Choi CCY, Roberts Buceta PM, Culver JC, Goodspeed CR, Bradley MC, Clarke CF, Basset GJ, Shepherd JN. PMID: 31121262; PMCID: PMC6874216.
      View in: PubMed   Mentions: 7     Fields:    Translation:AnimalsCells
    16. Human COQ10A and COQ10B are distinct lipid-binding START domain proteins required for coenzyme Q function. J Lipid Res. 2019 07; 60(7):1293-1310. Tsui HS, Pham NVB, Amer BR, Bradley MC, Gosschalk JE, Gallagher-Jones M, Ibarra H, Clubb RT, Blaby-Haas CE, Clarke CF. PMID: 31048406; PMCID: PMC6602128.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansAnimalsCells
    17. Ubiquinone Biosynthetic Complexes in Prokaryotes and Eukaryotes. Cell Chem Biol. 2019 04 18; 26(4):465-467. Tsui HS, Clarke CF. PMID: 31002800; PMCID: PMC6952117.
      View in: PubMed   Mentions: 7     Fields:    Translation:Animals
    18. The Endoplasmic Reticulum-Mitochondria Encounter Structure Complex Coordinates Coenzyme Q Biosynthesis. Contact (Thousand Oaks). 2019 Feb 22; 2:2515256418825409. Eisenberg-Bord M, Tsui HS, Antunes D, Fernández-Del-Río L, Bradley MC, Dunn CD, Nguyen TPT, Rapaport D, Clarke CF, Schuldiner M. PMID: 30937424; PMCID: PMC6441334.
      View in: PubMed   Mentions: 26  
    19. Treatment with 2,4-Dihydroxybenzoic Acid Prevents FSGS Progression and Renal Fibrosis in Podocyte-Specific Coq6 Knockout Mice. J Am Soc Nephrol. 2019 Mar; 30(3):393-405. Widmeier E, Airik M, Hugo H, Schapiro D, Wedel J, Ghosh CC, Nakayama M, Schneider R, Awad AM, Nag A, Cho J, Schueler M, Clarke CF, Airik R, Hildebrandt F. PMID: 30737270; PMCID: PMC6405149.
      View in: PubMed   Mentions: 26     Fields:    
    20. Coenzyme Q10 deficiencies: pathways in yeast and humans. Essays Biochem. 2018 07 20; 62(3):361-376. Awad AM, Bradley MC, Fernández-Del-Río L, Nag A, Tsui HS, Clarke CF. PMID: 29980630; PMCID: PMC6056717.
      View in: PubMed   Mentions: 53     Fields:    Translation:HumansAnimals
    21. Insights into an Ancient Atypical Kinase Essential for Biosynthesis of Coenzyme Q. Cell Chem Biol. 2018 02 15; 25(2):123-125. Clarke CF. PMID: 29452608.
      View in: PubMed   Mentions: 1     Fields:    Translation:Animals
    22. Chromatin-remodeling SWI/SNF complex regulates coenzyme Q6 synthesis and a metabolic shift to respiration in yeast. J Biol Chem. 2017 09 08; 292(36):14851-14866. Awad AM, Venkataramanan S, Nag A, Galivanche AR, Bradley MC, Neves LT, Douglass S, Clarke CF, Johnson TL. PMID: 28739803; PMCID: PMC5592666.
      View in: PubMed   Mentions: 9     Fields:    Translation:AnimalsCells
    23. Human COQ9 Rescues a coq9 Yeast Mutant by Enhancing Coenzyme Q Biosynthesis from 4-Hydroxybenzoic Acid and Stabilizing the CoQ-Synthome. Front Physiol. 2017; 8:463. He CH, Black DS, Allan CM, Meunier B, Rahman S, Clarke CF. PMID: 28736527; PMCID: PMC5500610.
      View in: PubMed   Mentions: 8  
    24. Kaempferol increases levels of coenzyme Q in kidney cells and serves as a biosynthetic ring precursor. Free Radic Biol Med. 2017 09; 110:176-187. Fernández-Del-Río L, Nag A, Gutiérrez Casado E, Ariza J, Awad AM, Joseph AI, Kwon O, Verdin E, de Cabo R, Schneider C, Torres JZ, Burón MI, Clarke CF, Villalba JM. PMID: 28603085; PMCID: PMC5539908.
      View in: PubMed   Mentions: 22     Fields:    Translation:HumansAnimalsCells
    25. Biochemistry: Unexpected role for vitamin B2. Nature. 2015 Jun 25; 522(7557):427-8. Clarke CF, Allan CM. PMID: 26083748.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    26. Yeast Coq9 controls deamination of coenzyme Q intermediates that derive from para-aminobenzoic acid. Biochim Biophys Acta. 2015 Sep; 1851(9):1227-39. He CH, Black DS, Nguyen TP, Wang C, Srinivasan C, Clarke CF. PMID: 26008578; PMCID: PMC4516658.
      View in: PubMed   Mentions: 17     Fields:    Translation:AnimalsCells
    27. Resveratrol and para-coumarate serve as ring precursors for coenzyme Q biosynthesis. J Lipid Res. 2015 Apr; 56(4):909-19. Xie LX, Williams KJ, He CH, Weng E, Khong S, Rose TE, Kwon O, Bensinger SJ, Marbois BN, Clarke CF. PMID: 25681964; PMCID: PMC4373747.
      View in: PubMed   Mentions: 24     Fields:    Translation:HumansAnimalsCells
    28. Identification of Coq11, a new coenzyme Q biosynthetic protein in the CoQ-synthome in Saccharomyces cerevisiae. J Biol Chem. 2015 Mar 20; 290(12):7517-34. Allan CM, Awad AM, Johnson JS, Shirasaki DI, Wang C, Blaby-Haas CE, Merchant SS, Loo JA, Clarke CF. PMID: 25631044; PMCID: PMC4367260.
      View in: PubMed   Mentions: 37     Fields:    Translation:Animals
    29. Isotope-reinforced polyunsaturated fatty acids protect mitochondria from oxidative stress. Free Radic Biol Med. 2015 May; 82:63-72. Andreyev AY, Tsui HS, Milne GL, Shmanai VV, Bekish AV, Fomich MA, Pham MN, Nong Y, Murphy AN, Clarke CF, Shchepinov MS. PMID: 25578654.
      View in: PubMed   Mentions: 24     Fields:    Translation:AnimalsCells
    30. Molecular characterization of the human COQ5 C-methyltransferase in coenzyme Q10 biosynthesis. Biochim Biophys Acta. 2014 Nov; 1841(11):1628-38. Nguyen TP, Casarin A, Desbats MA, Doimo M, Trevisson E, Santos-Ocaña C, Navas P, Clarke CF, Salviati L. PMID: 25152161; PMCID: PMC4331671.
      View in: PubMed   Mentions: 30     Fields:    
    31. The metabolite α-ketoglutarate extends lifespan by inhibiting ATP synthase and TOR. Nature. 2014 Jun 19; 510(7505):397-401. Chin RM, Fu X, Pai MY, Vergnes L, Hwang H, Deng G, Diep S, Lomenick B, Meli VS, Monsalve GC, Hu E, Whelan SA, Wang JX, Jung G, Solis GM, Fazlollahi F, Kaweeteerawat C, Quach A, Nili M, Krall AS, Godwin HA, Chang HR, Faull KF, Guo F, Jiang M, Trauger SA, Saghatelian A, Braas D, Christofk HR, Clarke CF, Teitell MA, Petrascheck M, Reue K, Jung ME, Frand AR, Huang J. PMID: 24828042; PMCID: PMC4263271.
      View in: PubMed   Mentions: 283     Fields:    Translation:HumansAnimalsCells
    32. Osmotic stress: Is CoQ a membrane stabilizer? Nat Chem Biol. 2014 Apr; 10(4):242-3. Clarke CF, Rowat AC, Gober JW. PMID: 24643237.
      View in: PubMed   Mentions: 7     Fields:    Translation:Cells
    33. Unusual kinetic isotope effects of deuterium reinforced polyunsaturated fatty acids in tocopherol-mediated free radical chain oxidations. J Am Chem Soc. 2014 Jan 22; 136(3):838-41. Lamberson CR, Xu L, Muchalski H, Montenegro-Burke JR, Shmanai VV, Bekish AV, McLean JA, Clarke CF, Shchepinov MS, Porter NA. PMID: 24380377; PMCID: PMC4578730.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansCells
    34. Coenzyme Q supplementation or over-expression of the yeast Coq8 putative kinase stabilizes multi-subunit Coq polypeptide complexes in yeast coq null mutants. Biochim Biophys Acta. 2014 Apr 04; 1841(4):630-44. He CH, Xie LX, Allan CM, Tran UC, Clarke CF. PMID: 24406904; PMCID: PMC3959571.
      View in: PubMed   Mentions: 52     Fields:    Translation:Animals
    35. ADCK4 mutations promote steroid-resistant nephrotic syndrome through CoQ10 biosynthesis disruption. J Clin Invest. 2013 Dec; 123(12):5179-89. Ashraf S, Gee HY, Woerner S, Xie LX, Vega-Warner V, Lovric S, Fang H, Song X, Cattran DC, Avila-Casado C, Paterson AD, Nitschké P, Bole-Feysot C, Cochat P, Esteve-Rudd J, Haberberger B, Allen SJ, Zhou W, Airik R, Otto EA, Barua M, Al-Hamed MH, Kari JA, Evans J, Bierzynska A, Saleem MA, Böckenhauer D, Kleta R, El Desoky S, Hacihamdioglu DO, Gok F, Washburn J, Wiggins RC, Choi M, Lifton RP, Levy S, Han Z, Salviati L, Prokisch H, Williams DS, Pollak M, Clarke CF, Pei Y, Antignac C, Hildebrandt F. PMID: 24270420; PMCID: PMC3859425.
      View in: PubMed   Mentions: 180     Fields:    Translation:HumansAnimalsCells
    36. Focal segmental glomerulosclerosis is associated with a PDSS2 haplotype and, independently, with a decreased content of coenzyme Q10. Am J Physiol Renal Physiol. 2013 Oct 15; 305(8):F1228-38. Gasser DL, Winkler CA, Peng M, An P, McKenzie LM, Kirk GD, Shi Y, Xie LX, Marbois BN, Clarke CF, Kopp JB. PMID: 23926186; PMCID: PMC3798722.
      View in: PubMed   Mentions: 30     Fields:    Translation:HumansCells
    37. A conserved START domain coenzyme Q-binding polypeptide is required for efficient Q biosynthesis, respiratory electron transport, and antioxidant function in Saccharomyces cerevisiae. Biochim Biophys Acta. 2013 Apr; 1831(4):776-791. Allan CM, Hill S, Morvaridi S, Saiki R, Johnson JS, Liau WS, Hirano K, Kawashima T, Ji Z, Loo JA, Shepherd JN, Clarke CF. PMID: 23270816; PMCID: PMC3909687.
      View in: PubMed   Mentions: 28     Fields:    Translation:AnimalsCells
    38. Delayed accumulation of intestinal coliform bacteria enhances life span and stress resistance in Caenorhabditis elegans fed respiratory deficient E. coli. BMC Microbiol. 2012 Dec 20; 12:300. Gomez F, Monsalve GC, Tse V, Saiki R, Weng E, Lee L, Srinivasan C, Frand AR, Clarke CF. PMID: 23256533; PMCID: PMC3548685.
      View in: PubMed   Mentions: 21     Fields:    Translation:AnimalsCells
    39. Folate status of gut microbiome affects Caenorhabditis elegans lifespan. BMC Biol. 2012 Jul 31; 10:66. Nguyen TP, Clarke CF. PMID: 22849295; PMCID: PMC3409036.
      View in: PubMed   Mentions: 9     Fields:    Translation:AnimalsCells
    40. Restoring de novo coenzyme Q biosynthesis in Caenorhabditis elegans coq-3 mutants yields profound rescue compared to exogenous coenzyme Q supplementation. Gene. 2012 Sep 10; 506(1):106-16. Gomez F, Saiki R, Chin R, Srinivasan C, Clarke CF. PMID: 22735617; PMCID: PMC3437764.
      View in: PubMed   Mentions: 13     Fields:    Translation:AnimalsCells
    41. Small amounts of isotope-reinforced polyunsaturated fatty acids suppress lipid autoxidation. Free Radic Biol Med. 2012 Aug 15; 53(4):893-906. Hill S, Lamberson CR, Xu L, To R, Tsui HS, Shmanai VV, Bekish AV, Awad AM, Marbois BN, Cantor CR, Porter NA, Clarke CF, Shchepinov MS. PMID: 22705367; PMCID: PMC3437768.
      View in: PubMed   Mentions: 51     Fields:    Translation:AnimalsCells
    42. Overexpression of the Coq8 kinase in Saccharomyces cerevisiae coq null mutants allows for accumulation of diagnostic intermediates of the coenzyme Q6 biosynthetic pathway. J Biol Chem. 2012 Jul 06; 287(28):23571-81. Xie LX, Ozeir M, Tang JY, Chen JY, Jaquinod SK, Fontecave M, Clarke CF, Pierrel F. PMID: 22593570; PMCID: PMC3390632.
      View in: PubMed   Mentions: 54     Fields:    Translation:AnimalsCells
    43. Coq6 hydroxylase: unmasked and bypassed. Chem Biol. 2011 Sep 23; 18(9):1069-70. Clarke CF. PMID: 21944743; PMCID: PMC3245979.
      View in: PubMed   Mentions: 1     Fields:    
    44. Caenorhabditis elegans UCP4 protein controls complex II-mediated oxidative phosphorylation through succinate transport. J Biol Chem. 2011 Oct 28; 286(43):37712-20. Pfeiffer M, Kayzer EB, Yang X, Abramson E, Kenaston MA, Lago CU, Lo HH, Sedensky MM, Lunceford A, Clarke CF, Wu SJ, McLeod C, Finkel T, Morgan PG, Mills EM. PMID: 21862587; PMCID: PMC3199514.
      View in: PubMed   Mentions: 20     Fields:    Translation:AnimalsCells
    45. 176th ENMC International Workshop: diagnosis and treatment of coenzyme Q₁₀ deficiency. Neuromuscul Disord. 2012 Jan; 22(1):76-86. Rahman S, Clarke CF, Hirano M. PMID: 21723727; PMCID: PMC3222743.
      View in: PubMed   Mentions: 36     Fields:    Translation:HumansAnimals
    46. Probucol ameliorates renal and metabolic sequelae of primary CoQ deficiency in Pdss2 mutant mice. EMBO Mol Med. 2011 Jul; 3(7):410-27. Falk MJ, Polyak E, Zhang Z, Peng M, King R, Maltzman JS, Okwuego E, Horyn O, Nakamaru-Ogiso E, Ostrovsky J, Xie LX, Chen JY, Marbois B, Nissim I, Clarke CF, Gasser DL. PMID: 21567994; PMCID: PMC3394513.
      View in: PubMed   Mentions: 33     Fields:    Translation:AnimalsCells
    47. COQ6 mutations in human patients produce nephrotic syndrome with sensorineural deafness. J Clin Invest. 2011 May; 121(5):2013-24. Heeringa SF, Chernin G, Chaki M, Zhou W, Sloan AJ, Ji Z, Xie LX, Salviati L, Hurd TW, Vega-Warner V, Killen PD, Raphael Y, Ashraf S, Ovunc B, Schoeb DS, McLaughlin HM, Airik R, Vlangos CN, Gbadegesin R, Hinkes B, Saisawat P, Trevisson E, Doimo M, Casarin A, Pertegato V, Giorgi G, Prokisch H, Rötig A, Nürnberg G, Becker C, Wang S, Ozaltin F, Topaloglu R, Bakkaloglu A, Bakkaloglu SA, Müller D, Beissert A, Mir S, Berdeli A, Varpizen S, Zenker M, Matejas V, Santos-Ocaña C, Navas P, Kusakabe T, Kispert A, Akman S, Soliman NA, Krick S, Mundel P, Reiser J, Nürnberg P, Clarke CF, Wiggins RC, Faul C, Hildebrandt F. PMID: 21540551; PMCID: PMC3083770.
      View in: PubMed   Mentions: 195     Fields:    Translation:HumansAnimalsCells
    48. Expression of the human atypical kinase ADCK3 rescues coenzyme Q biosynthesis and phosphorylation of Coq polypeptides in yeast coq8 mutants. Biochim Biophys Acta. 2011 May; 1811(5):348-60. Xie LX, Hsieh EJ, Watanabe S, Allan CM, Chen JY, Tran UC, Clarke CF. PMID: 21296186; PMCID: PMC3075350.
      View in: PubMed   Mentions: 57     Fields:    Translation:HumansAnimalsCells
    49. Isotope-reinforced polyunsaturated fatty acids protect yeast cells from oxidative stress. Free Radic Biol Med. 2011 Jan 01; 50(1):130-8. Hill S, Hirano K, Shmanai VV, Marbois BN, Vidovic D, Bekish AV, Kay B, Tse V, Fine J, Clarke CF, Shchepinov MS. PMID: 20955788; PMCID: PMC3014413.
      View in: PubMed   Mentions: 32     Fields:    Translation:Animals
    50. Paraoxonase 2 deficiency alters mitochondrial function and exacerbates the development of atherosclerosis. Antioxid Redox Signal. 2011 Feb 01; 14(3):341-51. Devarajan A, Bourquard N, Hama S, Navab M, Grijalva VR, Morvardi S, Clarke CF, Vergnes L, Reue K, Teiber JF, Reddy ST. PMID: 20578959; PMCID: PMC3011913.
      View in: PubMed   Mentions: 99     Fields:    Translation:HumansAnimalsCells
    51. para-Aminobenzoic acid is a precursor in coenzyme Q6 biosynthesis in Saccharomyces cerevisiae. J Biol Chem. 2010 Sep 03; 285(36):27827-38. Marbois B, Xie LX, Choi S, Hirano K, Hyman K, Clarke CF. PMID: 20592037; PMCID: PMC2934650.
      View in: PubMed   Mentions: 58     Fields:    Translation:AnimalsCells
    52. Target identification using drug affinity responsive target stability (DARTS). Proc Natl Acad Sci U S A. 2009 Dec 22; 106(51):21984-9. Lomenick B, Hao R, Jonai N, Chin RM, Aghajan M, Warburton S, Wang J, Wu RP, Gomez F, Loo JA, Wohlschlegel JA, Vondriska TM, Pelletier J, Herschman HR, Clardy J, Clarke CF, Huang J. PMID: 19995983; PMCID: PMC2789755.
      View in: PubMed   Mentions: 357     Fields:    Translation:Cells
    53. Evidence that ubiquinone is a required intermediate for rhodoquinone biosynthesis in Rhodospirillum rubrum. J Bacteriol. 2010 Jan; 192(2):436-45. Brajcich BC, Iarocci AL, Johnstone LA, Morgan RK, Lonjers ZT, Hotchko MJ, Muhs JD, Kieffer A, Reynolds BJ, Mandel SM, Marbois BN, Clarke CF, Shepherd JN. PMID: 19933361; PMCID: PMC2805321.
      View in: PubMed   Mentions: 18     Fields:    Translation:Cells
    54. A regulated response to impaired respiration slows behavioral rates and increases lifespan in Caenorhabditis elegans. PLoS Genet. 2009 Apr; 5(4):e1000450. Cristina D, Cary M, Lunceford A, Clarke C, Kenyon C. PMID: 19360127; PMCID: PMC2660839.
      View in: PubMed   Mentions: 84     Fields:    Translation:AnimalsCells
    55. Genetic evidence for the requirement of the endocytic pathway in the uptake of coenzyme Q6 in Saccharomyces cerevisiae. Biochim Biophys Acta. 2009 Jun; 1788(6):1238-48. Padilla-López S, Jiménez-Hidalgo M, Martín-Montalvo A, Clarke CF, Navas P, Santos-Ocaña C. PMID: 19345667; PMCID: PMC3070215.
      View in: PubMed   Mentions: 12     Fields:    Translation:AnimalsCells
    56. Hydroxylation of demethoxy-Q6 constitutes a control point in yeast coenzyme Q6 biosynthesis. Cell Mol Life Sci. 2009 Jan; 66(1):173-86. Padilla S, Tran UC, Jiménez-Hidalgo M, López-Martín JM, Martín-Montalvo A, Clarke CF, Navas P, Santos-Ocaña C. PMID: 19002377; PMCID: PMC3070445.
      View in: PubMed   Mentions: 30     Fields:    Translation:AnimalsCells
    57. The yeast Coq4 polypeptide organizes a mitochondrial protein complex essential for coenzyme Q biosynthesis. Biochim Biophys Acta. 2009 Jan; 1791(1):69-75. Marbois B, Gin P, Gulmezian M, Clarke CF. PMID: 19022396; PMCID: PMC2627766.
      View in: PubMed   Mentions: 49     Fields:    Translation:AnimalsCells
    58. Lipids including cholesteryl linoleate and cholesteryl arachidonate contribute to the inherent antibacterial activity of human nasal fluid. J Immunol. 2008 Sep 15; 181(6):4177-87. Do TQ, Moshkani S, Castillo P, Anunta S, Pogosyan A, Cheung A, Marbois B, Faull KF, Ernst W, Chiang SM, Fujii G, Clarke CF, Foster K, Porter E. PMID: 18768875; PMCID: PMC2597438.
      View in: PubMed   Mentions: 48     Fields:    Translation:HumansCells
    59. Coenzyme Q10 supplementation rescues renal disease in Pdss2kd/kd mice with mutations in prenyl diphosphate synthase subunit 2. Am J Physiol Renal Physiol. 2008 Nov; 295(5):F1535-44. Saiki R, Lunceford AL, Shi Y, Marbois B, King R, Pachuski J, Kawamukai M, Gasser DL, Clarke CF. PMID: 18784258; PMCID: PMC2584909.
      View in: PubMed   Mentions: 49     Fields:    Translation:AnimalsCells
    60. Lipidomic analysis and electron transport chain activities in C57BL/6J mouse brain mitochondria. J Neurochem. 2008 Jul; 106(1):299-312. Kiebish MA, Han X, Cheng H, Lunceford A, Clarke CF, Moon H, Chuang JH, Seyfried TN. PMID: 18373617; PMCID: PMC3104050.
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    61. Primary coenzyme Q deficiency in Pdss2 mutant mice causes isolated renal disease. PLoS Genet. 2008 Apr 25; 4(4):e1000061. Peng M, Falk MJ, Haase VH, King R, Polyak E, Selak M, Yudkoff M, Hancock WW, Meade R, Saiki R, Lunceford AL, Clarke CF, Gasser DL. PMID: 18437205; PMCID: PMC2291193.
      View in: PubMed   Mentions: 77     Fields:    Translation:AnimalsCells
    62. Altered bacterial metabolism, not coenzyme Q content, is responsible for the lifespan extension in Caenorhabditis elegans fed an Escherichia coli diet lacking coenzyme Q. Aging Cell. 2008 Jun; 7(3):291-304. Saiki R, Lunceford AL, Bixler T, Dang P, Lee W, Furukawa S, Larsen PL, Clarke CF. PMID: 18267002; PMCID: PMC3104051.
      View in: PubMed   Mentions: 29     Fields:    Translation:AnimalsCells
    63. The role of UbiX in Escherichia coli coenzyme Q biosynthesis. Arch Biochem Biophys. 2007 Nov 15; 467(2):144-53. Gulmezian M, Hyman KR, Marbois BN, Clarke CF, Javor GT. PMID: 17889824; PMCID: PMC2475804.
      View in: PubMed   Mentions: 37     Fields:    Translation:Cells
    64. Endogenous synthesis of coenzyme Q in eukaryotes. Mitochondrion. 2007 Jun; 7 Suppl:S62-71. Tran UC, Clarke CF. PMID: 17482885; PMCID: PMC1974887.
      View in: PubMed   Mentions: 124     Fields:    Translation:HumansAnimalsCells
    65. Saccharomyces cerevisiae Coq9 polypeptide is a subunit of the mitochondrial coenzyme Q biosynthetic complex. Arch Biochem Biophys. 2007 Jul 01; 463(1):19-26. Hsieh EJ, Gin P, Gulmezian M, Tran UC, Saiki R, Marbois BN, Clarke CF. PMID: 17391640; PMCID: PMC2080827.
      View in: PubMed   Mentions: 49     Fields:    Translation:AnimalsCells
    66. Genetic evidence for an interaction of the UbiG O-methyltransferase with UbiX in Escherichia coli coenzyme Q biosynthesis. J Bacteriol. 2006 Sep; 188(17):6435-9. Gulmezian M, Zhang H, Javor GT, Clarke CF. PMID: 16923914; PMCID: PMC1595381.
      View in: PubMed   Mentions: 4     Fields:    Translation:Cells
    67. Complementation of Saccharomyces cerevisiae coq7 mutants by mitochondrial targeting of the Escherichia coli UbiF polypeptide: two functions of yeast Coq7 polypeptide in coenzyme Q biosynthesis. J Biol Chem. 2006 Jun 16; 281(24):16401-9. Tran UC, Marbois B, Gin P, Gulmezian M, Jonassen T, Clarke CF. PMID: 16624818; PMCID: PMC3066048.
      View in: PubMed   Mentions: 38     Fields:    Translation:AnimalsCells
    68. The Saccharomyces cerevisiae COQ10 gene encodes a START domain protein required for function of coenzyme Q in respiration. J Biol Chem. 2005 Dec 30; 280(52):42627-35. Barros MH, Johnson A, Gin P, Marbois BN, Clarke CF, Tzagoloff A. PMID: 16230336.
      View in: PubMed   Mentions: 41     Fields:    Translation:HumansAnimalsCells
    69. COQ9, a new gene required for the biosynthesis of coenzyme Q in Saccharomyces cerevisiae. J Biol Chem. 2005 Sep 09; 280(36):31397-404. Johnson A, Gin P, Marbois BN, Hsieh EJ, Wu M, Barros MH, Clarke CF, Tzagoloff A. PMID: 16027161.
      View in: PubMed   Mentions: 48     Fields:    Translation:Animals
    70. Coq3 and Coq4 define a polypeptide complex in yeast mitochondria for the biosynthesis of coenzyme Q. J Biol Chem. 2005 May 27; 280(21):20231-8. Marbois B, Gin P, Faull KF, Poon WW, Lee PT, Strahan J, Shepherd JN, Clarke CF. PMID: 15792955.
      View in: PubMed   Mentions: 44     Fields:    Translation:AnimalsCells
    71. Genetic evidence for a multi-subunit complex in coenzyme Q biosynthesis in yeast and the role of the Coq1 hexaprenyl diphosphate synthase. J Biol Chem. 2005 Jan 28; 280(4):2676-81. Gin P, Clarke CF. PMID: 15548532.
      View in: PubMed   Mentions: 33     Fields:    Translation:AnimalsCells
    72. Non-mitochondrial complex I proteins in a hydrogenosomal oxidoreductase complex. Nature. 2004 Oct 28; 431(7012):1103-7. Dyall SD, Yan W, Delgadillo-Correa MG, Lunceford A, Loo JA, Clarke CF, Johnson PJ. PMID: 15510149.
      View in: PubMed   Mentions: 31     Fields:    Translation:AnimalsCells
    73. A tRNA(TRP) gene mediates the suppression of cbs2-223 previously attributed to ABC1/COQ8. Biochem Biophys Res Commun. 2004 Apr 30; 317(2):648-53. Hsieh EJ, Dinoso JB, Clarke CF. PMID: 15063807.
      View in: PubMed   Mentions: 17     Fields:    Translation:Animals
    74. Ubiquinone is not required for proton conductance by uncoupling protein 1 in yeast mitochondria. Biochem J. 2004 Apr 15; 379(Pt 2):309-15. Esteves TC, Echtay KS, Jonassen T, Clarke CF, Brand MD. PMID: 14680474; PMCID: PMC1224067.
      View in: PubMed   Mentions: 15     Fields:    Translation:AnimalsCells
    75. Demethoxy-Q, an intermediate of coenzyme Q biosynthesis, fails to support respiration in Saccharomyces cerevisiae and lacks antioxidant activity. J Biol Chem. 2004 Jun 18; 279(25):25995-6004. Padilla S, Jonassen T, Jiménez-Hidalgo MA, Fernández-Ayala DJ, López-Lluch G, Marbois B, Navas P, Clarke CF, Santos-Ocaña C. PMID: 15078893.
      View in: PubMed   Mentions: 29     Fields:    Translation:AnimalsCells
    76. Yeast Coq5 C-methyltransferase is required for stability of other polypeptides involved in coenzyme Q biosynthesis. J Biol Chem. 2004 Mar 12; 279(11):10052-9. Baba SW, Belogrudov GI, Lee JC, Lee PT, Strahan J, Shepherd JN, Clarke CF. PMID: 14701817.
      View in: PubMed   Mentions: 29     Fields:    Translation:HumansAnimalsCells
    77. Reproductive fitness and quinone content of Caenorhabditis elegans clk-1 mutants fed coenzyme Q isoforms of varying length. J Biol Chem. 2003 Dec 19; 278(51):51735-42. Jonassen T, Davis DE, Larsen PL, Clarke CF. PMID: 14530273.
      View in: PubMed   Mentions: 8     Fields:    Translation:AnimalsCells
    78. The Saccharomyces cerevisiae COQ6 gene encodes a mitochondrial flavin-dependent monooxygenase required for coenzyme Q biosynthesis. J Biol Chem. 2003 Jul 11; 278(28):25308-16. Gin P, Hsu AY, Rothman SC, Jonassen T, Lee PT, Tzagoloff A, Clarke CF. PMID: 12721307.
      View in: PubMed   Mentions: 30     Fields:    Translation:AnimalsCells
    79. Development and fertility in Caenorhabditis elegans clk-1 mutants depend upon transport of dietary coenzyme Q8 to mitochondria. J Biol Chem. 2002 Nov 22; 277(47):45020-7. Jonassen T, Marbois BN, Faull KF, Clarke CF, Larsen PL. PMID: 12324451.
      View in: PubMed   Mentions: 39     Fields:    Translation:AnimalsCells
    80. Uptake of exogenous coenzyme Q and transport to mitochondria is required for bc1 complex stability in yeast coq mutants. J Biol Chem. 2002 Mar 29; 277(13):10973-81. Santos-Ocaña C, Do TQ, Padilla S, Navas P, Clarke CF. PMID: 11788608.
      View in: PubMed   Mentions: 36     Fields:    Translation:AnimalsCells
    81. Extension of life-span in Caenorhabditis elegans by a diet lacking coenzyme Q. Science. 2002 Jan 04; 295(5552):120-3. Larsen PL, Clarke CF. PMID: 11778046.
      View in: PubMed   Mentions: 58     Fields:    Translation:AnimalsCells
    82. Yeast COQ4 encodes a mitochondrial protein required for coenzyme Q synthesis. Arch Biochem Biophys. 2001 Aug 01; 392(1):48-58. Belogrudov GI, Lee PT, Jonassen T, Hsu AY, Gin P, Clarke CF. PMID: 11469793.
      View in: PubMed   Mentions: 32     Fields:    Translation:AnimalsCells
    83. A defect in coenzyme Q biosynthesis is responsible for the respiratory deficiency in Saccharomyces cerevisiae abc1 mutants. J Biol Chem. 2001 May 25; 276(21):18161-8. Do TQ, Hsu AY, Jonassen T, Lee PT, Clarke CF. PMID: 11279158.
      View in: PubMed   Mentions: 47     Fields:    Translation:AnimalsCells
    84. A dietary source of coenzyme Q is essential for growth of long-lived Caenorhabditis elegans clk-1 mutants. Proc Natl Acad Sci U S A. 2001 Jan 16; 98(2):421-6. Jonassen T, Larsen PL, Clarke CF. PMID: 11136229; PMCID: PMC14601.
      View in: PubMed   Mentions: 55     Fields:    Translation:HumansAnimalsCells
    85. Identification of Escherichia coli ubiB, a gene required for the first monooxygenase step in ubiquinone biosynthesis. J Bacteriol. 2000 Sep; 182(18):5139-46. Poon WW, Davis DE, Ha HT, Jonassen T, Rather PN, Clarke CF. PMID: 10960098; PMCID: PMC94662.
      View in: PubMed   Mentions: 62     Fields:    Translation:AnimalsCells
    86. Isolation and functional expression of human COQ3, a gene encoding a methyltransferase required for ubiquinone biosynthesis. J Biol Chem. 2000 Apr 28; 275(17):12381-7. Jonassen T, Clarke CF. PMID: 10777520.
      View in: PubMed   Mentions: 34     Fields:    Translation:HumansAnimalsCells
    87. Genetic evidence for a multi-subunit complex in the O-methyltransferase steps of coenzyme Q biosynthesis. Biochim Biophys Acta. 2000 Apr 12; 1484(2-3):287-97. Hsu AY, Do TQ, Lee PT, Clarke CF. PMID: 10760477.
      View in: PubMed   Mentions: 25     Fields:    Translation:Animals
    88. Conservation of the Caenorhabditis elegans timing gene clk-1 from yeast to human: a gene required for ubiquinone biosynthesis with potential implications for aging. Mamm Genome. 1999 Oct; 10(10):1000-4. Vajo Z, King LM, Jonassen T, Wilkin DJ, Ho N, Munnich A, Clarke CF, Francomano CA. PMID: 10501970.
      View in: PubMed   Mentions: 22     Fields:    Translation:HumansAnimalsCells
    89. Yeast and rat Coq3 and Escherichia coli UbiG polypeptides catalyze both O-methyltransferase steps in coenzyme Q biosynthesis. J Biol Chem. 1999 Jul 30; 274(31):21665-72. Poon WW, Barkovich RJ, Hsu AY, Frankel A, Lee PT, Shepherd JN, Myles DC, Clarke CF. PMID: 10419476.
      View in: PubMed   Mentions: 43     Fields:    Translation:AnimalsCells
    90. Characterization of Saccharomyces cerevisiae ubiquinone-deficient mutants. Biofactors. 1999; 9(2-4):121-9. Schultz JR, Clarke CF. PMID: 10416023.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    91. Genetic evidence for coenzyme Q requirement in plasma membrane electron transport. J Bioenerg Biomembr. 1998 Oct; 30(5):465-75. Santos-Ocaña C, Villalba JM, Córdoba F, Padilla S, Crane FL, Clarke CF, Navas P. PMID: 9932649.
      View in: PubMed   Mentions: 14     Fields:    Translation:AnimalsCells
    92. Coenzyme Q6 and iron reduction are responsible for the extracellular ascorbate stabilization at the plasma membrane of Saccharomyces cerevisiae. J Biol Chem. 1998 Apr 03; 273(14):8099-105. Santos-Ocaña C, Córdoba F, Crane FL, Clarke CF, Navas P. PMID: 9525912.
      View in: PubMed   Mentions: 12     Fields:    Translation:AnimalsCells
    93. Yeast Clk-1 homologue (Coq7/Cat5) is a mitochondrial protein in coenzyme Q synthesis. J Biol Chem. 1998 Feb 06; 273(6):3351-7. Jonassen T, Proft M, Randez-Gil F, Schultz JR, Marbois BN, Entian KD, Clarke CF. PMID: 9452453.
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    94. Characterization of the COQ5 gene from Saccharomyces cerevisiae. Evidence for a C-methyltransferase in ubiquinone biosynthesis. J Biol Chem. 1997 Apr 04; 272(14):9182-8. Barkovich RJ, Shtanko A, Shepherd JA, Lee PT, Myles DC, Tzagoloff A, Clarke CF. PMID: 9083049.
      View in: PubMed   Mentions: 33     Fields:    Translation:AnimalsCells
    95. A C-methyltransferase involved in both ubiquinone and menaquinone biosynthesis: isolation and identification of the Escherichia coli ubiE gene. J Bacteriol. 1997 Mar; 179(5):1748-54. Lee PT, Hsu AY, Ha HT, Clarke CF. PMID: 9045837; PMCID: PMC178890.
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    96. Sensitivity to treatment with polyunsaturated fatty acids is a general characteristic of the ubiquinone-deficient yeast coq mutants. Mol Aspects Med. 1997; 18 Suppl:S121-7. Poon WW, Do TQ, Marbois BN, Clarke CF. PMID: 9266513.
      View in: PubMed   Mentions: 20     Fields:    Translation:AnimalsCells
    97. Complementation of coq3 mutant yeast by mitochondrial targeting of the Escherichia coli UbiG polypeptide: evidence that UbiG catalyzes both O-methylation steps in ubiquinone biosynthesis. Biochemistry. 1996 Jul 30; 35(30):9797-806. Hsu AY, Poon WW, Shepherd JA, Myles DC, Clarke CF. PMID: 8703953.
      View in: PubMed   Mentions: 50     Fields:    Translation:AnimalsCells
    98. Enhanced sensitivity of ubiquinone-deficient mutants of Saccharomyces cerevisiae to products of autoxidized polyunsaturated fatty acids. Proc Natl Acad Sci U S A. 1996 Jul 23; 93(15):7534-9. Do TQ, Schultz JR, Clarke CF. PMID: 8755509; PMCID: PMC38780.
      View in: PubMed   Mentions: 46     Fields:    Translation:AnimalsCells
    99. Isolation and sequencing of the rat Coq7 gene and the mapping of mouse Coq7 to chromosome 7. Arch Biochem Biophys. 1996 Jun 15; 330(2):285-9. Jonassen T, Marbois BN, Kim L, Chin A, Xia YR, Lusis AJ, Clarke CF. PMID: 8660658.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansAnimalsCells
    100. Autoxidation of ubiquinol-6 is independent of superoxide dismutase. Biochemistry. 1996 May 28; 35(21):6595-603. Schultz JR, Ellerby LM, Gralla EB, Valentine JS, Clarke CF. PMID: 8639607.
      View in: PubMed   Mentions: 6     Fields:    Translation:AnimalsCells
    101. The COQ7 gene encodes a protein in saccharomyces cerevisiae necessary for ubiquinone biosynthesis. J Biol Chem. 1996 Feb 09; 271(6):2995-3004. Marbois BN, Clarke CF. PMID: 8621692.
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    102. 3-Hexaprenyl-4-hydroxybenzoic acid forms a predominant intermediate pool in ubiquinone biosynthesis in Saccharomyces cerevisiae. Arch Biochem Biophys. 1995 Jul 10; 320(2):305-14. Poon WW, Marbois BN, Faull KF, Clarke CF. PMID: 7625838.
      View in: PubMed   Mentions: 14     Fields:    Translation:Animals
    103. Ubiquinone biosynthesis in eukaryotic cells: tissue distribution of mRNA encoding 3,4-dihydroxy-5-polyprenylbenzoate methyltransferase in the rat and mapping of the COQ3 gene to mouse chromosome 4. Arch Biochem Biophys. 1994 Aug 15; 313(1):83-8. Marbois BN, Xia YR, Lusis AJ, Clarke CF. PMID: 8053692.
      View in: PubMed   Mentions: 9     Fields:    Translation:Animals
    104. Cloning of a rat cDNA encoding dihydroxypolyprenylbenzoate methyltransferase by functional complementation of a Saccharomyces cerevisiae mutant deficient in ubiquinone biosynthesis. Gene. 1994 Jan 28; 138(1-2):213-7. Marbois BN, Hsu A, Pillai R, Colicelli J, Clarke CF. PMID: 8125303.
      View in: PubMed   Mentions: 7     Fields:    Translation:AnimalsCells
    105. Ubiquinone biosynthesis in Saccharomyces cerevisiae. Isolation and sequence of COQ3, the 3,4-dihydroxy-5-hexaprenylbenzoate methyltransferase gene. J Biol Chem. 1991 Sep 05; 266(25):16636-44. Clarke CF, Williams W, Teruya JH. PMID: 1885593.
      View in: PubMed   Mentions: 24     Fields:    Translation:AnimalsCells
    106. Testis-specific transcripts of rat farnesyl pyrophosphate synthetase are developmentally regulated and localized to haploid germ cells. Biol Reprod. 1991 Apr; 44(4):663-71. Teruya JH, Salido EC, Edwards PA, Clarke CF. PMID: 2043737.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    107. Testis-specific transcription initiation sites of rat farnesyl pyrophosphate synthetase mRNA. Mol Cell Biol. 1990 May; 10(5):2315-26. Teruya JH, Kutsunai SY, Spear DH, Edwards PA, Clarke CF. PMID: 2325654; PMCID: PMC360579.
      View in: PubMed   Mentions: 9     Fields:    Translation:AnimalsCells
    108. Dispersed family of human genes with sequence similarity to farnesyl pyrophosphate synthetase. Genomics. 1989 Oct; 5(3):493-500. Heinzmann C, Clarke CF, Klisak I, Mohandas T, Sparkes RS, Edwards PA, Lusis AJ. PMID: 2613235.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimalsCells
    109. Purification of complexes of nuclear oncogene p53 with rat and Escherichia coli heat shock proteins: in vitro dissociation of hsc70 and dnaK from murine p53 by ATP. Mol Cell Biol. 1988 Mar; 8(3):1206-15. Clarke CF, Cheng K, Frey AB, Stein R, Hinds PW, Levine AJ. PMID: 3285177; PMCID: PMC363265.
      View in: PubMed   Mentions: 33     Fields:    Translation:AnimalsCells
    110. Molecular cloning and sequence of a cholesterol-repressible enzyme related to prenyltransferase in the isoprene biosynthetic pathway. Mol Cell Biol. 1987 Sep; 7(9):3138-46. Clarke CF, Tanaka RD, Svenson K, Wamsley M, Fogelman AM, Edwards PA. PMID: 3670308; PMCID: PMC367948.
      View in: PubMed   Mentions: 22     Fields:    Translation:Cells
    111. Regulation of rat liver 3-hydroxy-3-methylglutaryl coenzyme A synthase and the chromosomal localization of the human gene. J Biol Chem. 1986 Dec 05; 261(34):16249-55. Mehrabian M, Callaway KA, Clarke CF, Tanaka RD, Greenspan M, Lusis AJ, Sparkes RS, Mohandas T, Edmond J, Fogelman AM, et al. PMID: 2877984.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansAnimalsCells
    112. Transcriptional regulation of the 3-hydroxy-3-methylglutaryl coenzyme A reductase gene in rat liver. J Biol Chem. 1985 Nov 15; 260(26):14363-7. Clarke CF, Fogelman AM, Edwards PA. PMID: 3850901.
      View in: PubMed   Mentions: 7     Fields:    Translation:AnimalsCells
    113. Role of mevalonate in regulation of cholesterol synthesis and 3-hydroxy-3-methylglutaryl coenzyme A reductase in cultured cells and their cytoplasts. J Lipid Res. 1985 Jul; 26(7):831-41. Popják G, Clarke CF, Hadley C, Meenan A. PMID: 2411835.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    114. Diurnal rhythm of rat liver mRNAs encoding 3-hydroxy-3-methylglutaryl coenzyme A reductase. Correlation of functional and total mRNA levels with enzyme activity and protein. J Biol Chem. 1984 Aug 25; 259(16):10439-47. Clarke CF, Fogelman AM, Edwards PA. PMID: 6540773.
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    115. Regulation of 3-hydroxy-3-methylglutaryl-coenzyme A reductase mRNA levels in rat liver. Proc Natl Acad Sci U S A. 1983 Jun; 80(11):3305-8. Clarke CF, Edwards PA, Lan SF, Tanaka RD, Fogelman AM. PMID: 6190175; PMCID: PMC394030.
      View in: PubMed   Mentions: 18     Fields:    Translation:AnimalsCells
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