Steven G Clarke

Title(s)Professor, Chemistry and Biochemistry
SchoolCollege of Letters and Science
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    Steven Clarke previously held the Elizabeth R. and Thomas E. Plott Chair in Gerontololgy.

    Collapse Research 
    Collapse Research Activities and Funding
    Linked Protein Repair, Proteolysis, and Oxidation in Aging
    NIH R21AG032303Aug 15, 2008 - Jul 31, 2011
    Role: Principal Investigator
    ENYZMES AFFECTING THE ACCUMULATION OF ALTERED PROTEINS
    NIH R01AG018000Jun 15, 2000 - May 31, 2005
    Role: Principal Investigator
    FASEB RESEARCH CONFERENCE ON BIOLOGICAL METHYLATION
    NIH R13GM052978Jul 1, 1995 - Jun 30, 1996
    Role: Principal Investigator
    ROLE OF PROTEIN METHYLATION IN CATARACT FORMATION
    NIH R01EY004942Jul 1, 1983 - Jun 30, 1987
    Role: Principal Investigator
    CONTROL OF EUCARYOTIC FUNCTION BY METHYLATION
    NIH R01GM026020Dec 1, 1978 - Jan 31, 2016
    Role: Principal Investigator
    CONTROL OF EUCARYOTIC FUNCTION BY METHYLATION
    NIH R37GM026020Dec 1, 1978 - Mar 31, 2010
    Role: Principal Investigator
    Research Tranining in Cellular and Molecular Biology
    NIH T32GM007185Jul 1, 1975 - Jun 30, 2021
    Role: Co-Principal Investigator

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    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Asymmetric and symmetric protein arginine methylation in methionine-addicted human cancer cells. PLoS One. 2023; 18(12):e0296291. Holtz AG, Lowe TL, Aoki Y, Kubota Y, Hoffman RM, Clarke SG. PMID: 38134182; PMCID: PMC10745221.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    2. Natural isoaspartyl protein modification of ZAP70 alters T cell responses in lupus. Autoimmunity. 2023 12; 56(1):2282945. Yang ML, Lam TT, Kanyo J, Kang I, Zhou ZS, Clarke SG, Mamula MJ. PMID: 37994408; PMCID: PMC10897934.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    3. Identification of a Protein Arginine Methyltransferase 7 (PRMT7)/Protein Arginine Methyltransferase 9 (PRMT9) Inhibitor. J Med Chem. 2023 10 12; 66(19):13665-13683. Feoli A, Iannelli G, Cipriano A, Milite C, Shen L, Wang Z, Hadjikyriacou A, Lowe TL, Safaeipour C, Viviano M, Sarno G, Morretta E, Monti MC, Yang Y, Clarke SG, Cosconati S, Castellano S, Sbardella G. PMID: 37560786; PMCID: PMC10578352.
      View in: PubMed   Mentions:    Fields:    Translation:Cells
    4. The exquisite specificity of human protein arginine methyltransferase 7 (PRMT7) toward Arg-X-Arg sites. PLoS One. 2023; 18(5):e0285812. Bondoc TJ, Lowe TL, Clarke SG. PMID: 37216364; PMCID: PMC10202292.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    5. Reversion of methionine addiction of osteosarcoma cells to methionine independence results in loss of malignancy, modulation of the epithelial-mesenchymal phenotype and alteration of histone-H3 lysine-methylation. Front Oncol. 2022; 12:1009548. Aoki Y, Han Q, Tome Y, Yamamoto J, Kubota Y, Masaki N, Obara K, Hamada K, Wang JD, Inubushi S, Bouvet M, Clarke SG, Nishida K, Hoffman RM. PMID: 36408173; PMCID: PMC9671209.
      View in: PubMed   Mentions: 10  
    6. Carbonyl Posttranslational Modification Associated With Early-Onset Type 1 Diabetes Autoimmunity. Diabetes. 2022 09 01; 71(9):1979-1993. Yang ML, Connolly SE, Gee RJ, Lam TT, Kanyo J, Peng J, Guyer P, Syed F, Tse HM, Clarke SG, Clarke CF, James EA, Speake C, Evans-Molina C, Arvan P, Herold KC, Wen L, Mamula MJ. PMID: 35730902; PMCID: PMC9450849.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansAnimalsCells
    7. Human protein arginine methyltransferases (PRMTs) can be optimally active under nonphysiological conditions. J Biol Chem. 2022 09; 298(9):102290. Lowe TL, Clarke SG. PMID: 35868559; PMCID: PMC9418908.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCells
    8. Human Protein-l-isoaspartate O-Methyltransferase Domain-Containing Protein 1 (PCMTD1) Associates with Cullin-RING Ligase Proteins. Biochemistry. 2022 05 17; 61(10):879-894. Warmack RA, Pang EZ, Peluso E, Lowenson JD, Ong JY, Torres JZ, Clarke SG. PMID: 35486881; PMCID: PMC9875861.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    9. Linkage of methionine addiction, histone lysine hypermethylation, and malignancy. iScience. 2022 Apr 15; 25(4):104162. Yamamoto J, Inubushi S, Han Q, Tashiro Y, Sugisawa N, Hamada K, Aoki Y, Miyake K, Matsuyama R, Bouvet M, Clarke SG, Endo I, Hoffman RM. PMID: 35434545; PMCID: PMC9010622.
      View in: PubMed   Mentions: 10  
    10. Extent and Instability of Trimethylation of Histone H3 Lysine Increases With Degree of Malignancy and Methionine Addiction. Cancer Genomics Proteomics. 2022 Jan-Feb; 19(1):12-18. Yamamoto J, Aoki Y, Inubushi S, Han Q, Hamada K, Tashiro Y, Miyake K, Matsuyama R, Bouvet M, Clarke SG, Endo I, Hoffman RM. PMID: 34949655; PMCID: PMC8717956.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansAnimalsCells
    11. l-Isoaspartyl Methyltransferase Deficiency in Zebrafish Leads to Impaired Calcium Signaling in the Brain. Front Genet. 2020; 11:612343. Soliman R, Cordero-Maldonado ML, Martins TG, Moein M, Conrotte JF, Warmack RA, Skupin A, Crawford AD, Clarke SG, Linster CL. PMID: 33552132; PMCID: PMC7859441.
      View in: PubMed   Mentions: 2  
    12. Human ARMT1 structure and substrate specificity indicates that it is a DUF89 family damage-control phosphatase. J Struct Biol. 2020 10 01; 212(1):107576. Dennis TN, Kenjic N, Kang AS, Lowenson JD, Kirkwood JS, Clarke SG, Perry JJP. PMID: 32682077.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimalsCells
    13. Protein Methylation and Translation: Role of Lysine Modification on the Function of Yeast Elongation Factor 1A. Biochemistry. 2019 12 10; 58(49):4997-5010. White JT, Cato T, Deramchi N, Gabunilas J, Roy KR, Wang C, Chanfreau GF, Clarke SG. PMID: 31738538; PMCID: PMC6913935.
      View in: PubMed   Mentions: 7     Fields:    Translation:AnimalsCells
    14. Structure of amyloid-β (20-34) with Alzheimer's-associated isomerization at Asp23 reveals a distinct protofilament interface. Nat Commun. 2019 07 26; 10(1):3357. Warmack RA, Boyer DR, Zee CT, Richards LS, Sawaya MR, Cascio D, Gonen T, Eisenberg DS, Clarke SG. PMID: 31350392; PMCID: PMC6659688.
      View in: PubMed   Mentions: 24     Fields:    Translation:HumansCells
    15. The l-isoaspartate modification within protein fragments in the aging lens can promote protein aggregation. J Biol Chem. 2019 08 09; 294(32):12203-12219. Warmack RA, Shawa H, Liu K, Lopez K, Loo JA, Horwitz J, Clarke SG. PMID: 31239355; PMCID: PMC6690693.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansCells
    16. PRMT7 as a unique member of the protein arginine methyltransferase family: A review. Arch Biochem Biophys. 2019 04 15; 665:36-45. Jain K, Clarke SG. PMID: 30802433; PMCID: PMC6461449.
      View in: PubMed   Mentions: 34     Fields:    Translation:HumansAnimalsCells
    17. The ribosome: A hot spot for the identification of new types of protein methyltransferases. J Biol Chem. 2018 07 06; 293(27):10438-10446. Clarke SG. PMID: 29743234; PMCID: PMC6036201.
      View in: PubMed   Mentions: 12     Fields:    Translation:AnimalsCells
    18. Epigenetic control via allosteric regulation of mammalian protein arginine methyltransferases. Proc Natl Acad Sci U S A. 2017 09 19; 114(38):10101-10106. Jain K, Jin CY, Clarke SG. PMID: 28874563; PMCID: PMC5617285.
      View in: PubMed   Mentions: 26     Fields:    Translation:HumansCells
    19. Caenorhabditis elegans PRMT-7 and PRMT-9 Are Evolutionarily Conserved Protein Arginine Methyltransferases with Distinct Substrate Specificities. Biochemistry. 2017 05 23; 56(20):2612-2626. Hadjikyriacou A, Clarke SG. PMID: 28441492; PMCID: PMC5503151.
      View in: PubMed   Mentions: 11     Fields:    Translation:AnimalsCells
    20. The Major Protein Arginine Methyltransferase in Trypanosoma brucei Functions as an Enzyme-Prozyme Complex. J Biol Chem. 2017 02 10; 292(6):2089-2100. Kafková L, Debler EW, Fisk JC, Jain K, Clarke SG, Read LK. PMID: 27998975; PMCID: PMC5313084.
      View in: PubMed   Mentions: 20     Fields:    Translation:AnimalsCells
    21. Determining the Mitochondrial Methyl Proteome in Saccharomyces cerevisiae using Heavy Methyl SILAC. J Proteome Res. 2016 12 02; 15(12):4436-4451. Caslavka Zempel KE, Vashisht AA, Barshop WD, Wohlschlegel JA, Clarke SG. PMID: 27696855; PMCID: PMC5148652.
      View in: PubMed   Mentions: 10     Fields:    Translation:AnimalsCells
    22. Protein Arginine Methyltransferase Product Specificity Is Mediated by Distinct Active-site Architectures. J Biol Chem. 2016 08 26; 291(35):18299-308. Jain K, Warmack RA, Debler EW, Hadjikyriacou A, Stavropoulos P, Clarke SG. PMID: 27387499; PMCID: PMC5000077.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansAnimalsCells
    23. Deuteration protects asparagine residues against racemization. Amino Acids. 2016 09; 48(9):2189-96. Lowenson JD, Shmanai VV, Shklyaruck D, Clarke SG, Shchepinov MS. PMID: 27169868; PMCID: PMC4990494.
      View in: PubMed   Mentions: 1     Fields:    
    24. Production of FAME biodiesel in E. coli by direct methylation with an insect enzyme. Sci Rep. 2016 Apr 07; 6:24239. Sherkhanov S, Korman TP, Clarke SG, Bowie JU. PMID: 27053100; PMCID: PMC4823748.
      View in: PubMed   Mentions: 9     Fields:    Translation:AnimalsCells
    25. Racemized and Isomerized Proteins in Aging Rat Teeth and Eye Lens. Rejuvenation Res. 2016 Aug; 19(4):309-17. Warmack RA, Mansilla E, Goya RG, Clarke SG. PMID: 26650547; PMCID: PMC4971426.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    26. A glutamate/aspartate switch controls product specificity in a protein arginine methyltransferase. Proc Natl Acad Sci U S A. 2016 Feb 23; 113(8):2068-73. Debler EW, Jain K, Warmack RA, Feng Y, Clarke SG, Blobel G, Stavropoulos P. PMID: 26858449; PMCID: PMC4776506.
      View in: PubMed   Mentions: 20     Fields:    Translation:AnimalsCells
    27. Methylation of yeast ribosomal protein Rpl3 promotes translational elongation fidelity. RNA. 2016 Apr; 22(4):489-98. Al-Hadid Q, Roy K, Chanfreau G, Clarke SG. PMID: 26826131; PMCID: PMC4793205.
      View in: PubMed   Mentions: 17     Fields:    Translation:AnimalsCells
    28. Ribosomal protein methyltransferases in the yeast Saccharomyces cerevisiae: Roles in ribosome biogenesis and translation. Biochem Biophys Res Commun. 2016 Feb 12; 470(3):552-557. Al-Hadid Q, White J, Clarke S. PMID: 26801560; PMCID: PMC4750496.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    29. 2-Hydroxyglutarate Inhibits ATP Synthase and mTOR Signaling. Cell Metab. 2015 Sep 01; 22(3):508-15. Fu X, Chin RM, Vergnes L, Hwang H, Deng G, Xing Y, Pai MY, Li S, Ta L, Fazlollahi F, Chen C, Prins RM, Teitell MA, Nathanson DA, Lai A, Faull KF, Jiang M, Clarke SG, Cloughesy TF, Graeber TG, Braas D, Christofk HR, Jung ME, Reue K, Huang J. PMID: 26190651; PMCID: PMC4663076.
      View in: PubMed   Mentions: 124     Fields:    Translation:HumansAnimalsCells
    30. Unique Features of Human Protein Arginine Methyltransferase 9 (PRMT9) and Its Substrate RNA Splicing Factor SF3B2. J Biol Chem. 2015 Jul 03; 290(27):16723-43. Hadjikyriacou A, Yang Y, Espejo A, Bedford MT, Clarke SG. PMID: 25979344; PMCID: PMC4505422.
      View in: PubMed   Mentions: 52     Fields:    Translation:HumansAnimalsCells
    31. PRMT9 is a type II methyltransferase that methylates the splicing factor SAP145. Nat Commun. 2015 Mar 04; 6:6428. Yang Y, Hadjikyriacou A, Xia Z, Gayatri S, Kim D, Zurita-Lopez C, Kelly R, Guo A, Li W, Clarke SG, Bedford MT. PMID: 25737013; PMCID: PMC4351962.
      View in: PubMed   Mentions: 98     Fields:    Translation:HumansCells
    32. The invertebrate Caenorhabditis elegans biosynthesizes ascorbate. Arch Biochem Biophys. 2015 Mar 01; 569:32-44. Patananan AN, Budenholzer LM, Pedraza ME, Torres ER, Adler LN, Clarke SG. PMID: 25668719; PMCID: PMC4357563.
      View in: PubMed   Mentions: 10     Fields:    Translation:Animals
    33. Ethanol-induced differential gene expression and acetyl-CoA metabolism in a longevity model of the nematode Caenorhabditis elegans. Exp Gerontol. 2015 Jan; 61:20-30. Patananan AN, Budenholzer LM, Eskin A, Torres ER, Clarke SG. PMID: 25449858; PMCID: PMC4289658.
      View in: PubMed   Mentions: 8     Fields:    Translation:Animals
    34. A new type of protein lysine methyltransferase trimethylates Lys-79 of elongation factor 1A. Biochem Biophys Res Commun. 2014 Dec 12; 455(3-4):382-9. Dzialo MC, Travaglini KJ, Shen S, Loo JA, Clarke SG. PMID: 25446118; PMCID: PMC4263273.
      View in: PubMed   Mentions: 13     Fields:    Translation:AnimalsCells
    35. Substrate specificity of human protein arginine methyltransferase 7 (PRMT7): the importance of acidic residues in the double E loop. J Biol Chem. 2014 Nov 21; 289(47):32604-16. Feng Y, Hadjikyriacou A, Clarke SG. PMID: 25294873; PMCID: PMC4239614.
      View in: PubMed   Mentions: 25     Fields:    Translation:HumansCells
    36. Translational roles of elongation factor 2 protein lysine methylation. J Biol Chem. 2014 Oct 31; 289(44):30511-30524. Dzialo MC, Travaglini KJ, Shen S, Roy K, Chanfreau GF, Loo JA, Clarke SG. PMID: 25231983; PMCID: PMC4215232.
      View in: PubMed   Mentions: 16     Fields:    Translation:AnimalsCells
    37. Histidine methylation of yeast ribosomal protein Rpl3p is required for proper 60S subunit assembly. Mol Cell Biol. 2014 Aug; 34(15):2903-16. Al-Hadid Q, Roy K, Munroe W, Dzialo MC, Chanfreau GF, Clarke SG. PMID: 24865971; PMCID: PMC4135575.
      View in: PubMed   Mentions: 21     Fields:    Translation:AnimalsCells
    38. Non-repair pathways for minimizing protein isoaspartyl damage in the yeast Saccharomyces cerevisiae. J Biol Chem. 2014 Jun 13; 289(24):16936-53. Patananan AN, Capri J, Whitelegge JP, Clarke SG. PMID: 24764295; PMCID: PMC4059137.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansAnimalsCells
    39. Mammalian protein arginine methyltransferase 7 (PRMT7) specifically targets RXR sites in lysine- and arginine-rich regions. J Biol Chem. 2013 Dec 27; 288(52):37010-25. Feng Y, Maity R, Whitelegge JP, Hadjikyriacou A, Li Z, Zurita-Lopez C, Al-Hadid Q, Clark AT, Bedford MT, Masson JY, Clarke SG. PMID: 24247247; PMCID: PMC3873558.
      View in: PubMed   Mentions: 79     Fields:    Translation:HumansAnimalsCells
    40. A novel small molecule methyltransferase is important for virulence in Candida albicans. ACS Chem Biol. 2013 Dec 20; 8(12):2785-93. Lissina E, Weiss D, Young B, Rella A, Cheung-Ong K, Del Poeta M, Clarke SG, Giaever G, Nislow C. PMID: 24083538; PMCID: PMC3928151.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    41. Thermal-stable proteins of fruit of long-living Sacred Lotus Nelumbo nucifera Gaertn var. China Antique. Trop Plant Biol. 2013 Sep 01; 6(2-3). Shen-Miller J, Lindner P, Xie Y, Villa S, Wooding K, Clarke SG, Loo RR, Loo JA. PMID: 24363819; PMCID: PMC3869599.
      View in: PubMed   Mentions: 9  
    42. An Arabidopsis ATP-dependent, DEAD-box RNA helicase loses activity upon IsoAsp formation but is restored by PROTEIN ISOASPARTYL METHYLTRANSFERASE. Plant Cell. 2013 Jul; 25(7):2573-86. Nayak NR, Putnam AA, Addepalli B, Lowenson JD, Chen T, Jankowsky E, Perry SE, Dinkins RD, Limbach PA, Clarke SG, Downie AB. PMID: 23903319; PMCID: PMC3753384.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansAnimalsCells
    43. Circumventing embryonic lethality with Lcmt1 deficiency: generation of hypomorphic Lcmt1 mice with reduced protein phosphatase 2A methyltransferase expression and defects in insulin signaling. PLoS One. 2013; 8(6):e65967. MacKay KB, Tu Y, Young SG, Clarke SG. PMID: 23840384; PMCID: PMC3688711.
      View in: PubMed   Mentions: 5     Fields:    Translation:AnimalsCells
    44. A novel automethylation reaction in the Aspergillus nidulans LaeA protein generates S-methylmethionine. J Biol Chem. 2013 May 17; 288(20):14032-14045. Patananan AN, Palmer JM, Garvey GS, Keller NP, Clarke SG. PMID: 23532849; PMCID: PMC3656261.
      View in: PubMed   Mentions: 31     Fields:    Translation:AnimalsCells
    45. Protein methylation at the surface and buried deep: thinking outside the histone box. Trends Biochem Sci. 2013 May; 38(5):243-52. Clarke SG. PMID: 23490039; PMCID: PMC3634909.
      View in: PubMed   Mentions: 81     Fields:    Translation:HumansAnimalsCells
    46. Integrated proteomic analysis of major isoaspartyl-containing proteins in the urine of wild type and protein L-isoaspartate O-methyltransferase-deficient mice. Anal Chem. 2013 Feb 19; 85(4):2423-30. Dai S, Ni W, Patananan AN, Clarke SG, Karger BL, Zhou ZS. PMID: 23327623; PMCID: PMC3599293.
      View in: PubMed   Mentions: 15     Fields:    Translation:AnimalsCells
    47. Loss of the major Type I arginine methyltransferase PRMT1 causes substrate scavenging by other PRMTs. Sci Rep. 2013; 3:1311. Dhar S, Vemulapalli V, Patananan AN, Huang GL, Di Lorenzo A, Richard S, Comb MJ, Guo A, Clarke SG, Bedford MT. PMID: 23419748; PMCID: PMC3575585.
      View in: PubMed   Mentions: 100     Fields:    Translation:HumansCells
    48. Lupus autoimmunity altered by cellular methylation metabolism. Autoimmunity. 2013 Feb; 46(1):21-31. Yang ML, Gee AJ, Gee RJ, Zurita-Lopez CI, Khare S, Clarke SG, Mamula MJ. PMID: 23039363; PMCID: PMC3543504.
      View in: PubMed   Mentions: 21     Fields:    Translation:HumansAnimalsCells
    49. Systems and trans-system level analysis identifies conserved iron deficiency responses in the plant lineage. Plant Cell. 2012 Oct; 24(10):3921-48. Urzica EI, Casero D, Yamasaki H, Hsieh SI, Adler LN, Karpowicz SJ, Blaby-Haas CE, Clarke SG, Loo JA, Pellegrini M, Merchant SS. PMID: 23043051; PMCID: PMC3517228.
      View in: PubMed   Mentions: 74     Fields:    Translation:AnimalsCells
    50. Wortmannin reduces insulin signaling and death in seizure-prone Pcmt1-/- mice. PLoS One. 2012; 7(10):e46719. MacKay KB, Lowenson JD, Clarke SG. PMID: 23071621; PMCID: PMC3465263.
      View in: PubMed   Mentions: 7     Fields:    Translation:AnimalsCells
    51. Identification of methylated proteins in the yeast small ribosomal subunit: a role for SPOUT methyltransferases in protein arginine methylation. Biochemistry. 2012 Jun 26; 51(25):5091-104. Young BD, Weiss DI, Zurita-Lopez CI, Webb KJ, Clarke SG, McBride AE. PMID: 22650761; PMCID: PMC3383884.
      View in: PubMed   Mentions: 36     Fields:    Translation:AnimalsCells
    52. Impact of oxidative stress on ascorbate biosynthesis in Chlamydomonas via regulation of the VTC2 gene encoding a GDP-L-galactose phosphorylase. J Biol Chem. 2012 Apr 20; 287(17):14234-45. Urzica EI, Adler LN, Page MD, Linster CL, Arbing MA, Casero D, Pellegrini M, Merchant SS, Clarke SG. PMID: 22393048; PMCID: PMC3340187.
      View in: PubMed   Mentions: 41     Fields:    Translation:AnimalsCells
    53. Caenorhabditis elegans battling starvation stress: low levels of ethanol prolong lifespan in L1 larvae. PLoS One. 2012; 7(1):e29984. Castro PV, Khare S, Young BD, Clarke SG. PMID: 22279556; PMCID: PMC3261173.
      View in: PubMed   Mentions: 24     Fields:    Translation:Animals
    54. Human protein arginine methyltransferase 7 (PRMT7) is a type III enzyme forming ω-NG-monomethylated arginine residues. J Biol Chem. 2012 Mar 09; 287(11):7859-70. Zurita-Lopez CI, Sandberg T, Kelly R, Clarke SG. PMID: 22241471; PMCID: PMC3318701.
      View in: PubMed   Mentions: 112     Fields:    Translation:HumansCells
    55. A systems biology approach reveals the role of a novel methyltransferase in response to chemical stress and lipid homeostasis. PLoS Genet. 2011 Oct; 7(10):e1002332. Lissina E, Young B, Urbanus ML, Guan XL, Lowenson J, Hoon S, Baryshnikova A, Riezman I, Michaut M, Riezman H, Cowen LE, Wenk MR, Clarke SG, Giaever G, Nislow C. PMID: 22028670; PMCID: PMC3197675.
      View in: PubMed   Mentions: 10     Fields:    Translation:AnimalsCells
    56. The interplay between protein L-isoaspartyl methyltransferase activity and insulin-like signaling to extend lifespan in Caenorhabditis elegans. PLoS One. 2011; 6(6):e20850. Khare S, Linster CL, Clarke SG. PMID: 21695191; PMCID: PMC3113807.
      View in: PubMed   Mentions: 11     Fields:    Translation:AnimalsCells
    57. A novel GDP-D-glucose phosphorylase involved in quality control of the nucleoside diphosphate sugar pool in Caenorhabditis elegans and mammals. J Biol Chem. 2011 Jun 17; 286(24):21511-23. Adler LN, Gomez TA, Clarke SG, Linster CL. PMID: 21507950; PMCID: PMC3122210.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansAnimalsCells
    58. The ribosomal l1 protuberance in yeast is methylated on a lysine residue catalyzed by a seven-beta-strand methyltransferase. J Biol Chem. 2011 May 27; 286(21):18405-13. Webb KJ, Al-Hadid Q, Zurita-Lopez CI, Young BD, Lipson RS, Clarke SG. PMID: 21460220; PMCID: PMC3099657.
      View in: PubMed   Mentions: 18     Fields:    Translation:AnimalsCells
    59. Protein-arginine methyltransferase 1 (PRMT1) methylates Ash2L, a shared component of mammalian histone H3K4 methyltransferase complexes. J Biol Chem. 2011 Apr 08; 286(14):12234-44. Butler JS, Zurita-Lopez CI, Clarke SG, Bedford MT, Dent SY. PMID: 21285357; PMCID: PMC3069427.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansCells
    60. Uncovering the human methyltransferasome. Mol Cell Proteomics. 2011 Jan; 10(1):M110.000976. Petrossian TC, Clarke SG. PMID: 20930037; PMCID: PMC3013446.
      View in: PubMed   Mentions: 150     Fields:    Translation:HumansAnimalsCells
    61. Substrates of the Arabidopsis thaliana protein isoaspartyl methyltransferase 1 identified using phage display and biopanning. J Biol Chem. 2010 Nov 26; 285(48):37281-92. Chen T, Nayak N, Majee SM, Lowenson J, Schäfermeyer KR, Eliopoulos AC, Lloyd TD, Dinkins R, Perry SE, Forsthoefel NR, Clarke SG, Vernon DM, Zhou ZS, Rejtar T, Downie AB. PMID: 20870712; PMCID: PMC2988334.
      View in: PubMed   Mentions: 20     Fields:    Translation:AnimalsCells
    62. A novel 3-methylhistidine modification of yeast ribosomal protein Rpl3 is dependent upon the YIL110W methyltransferase. J Biol Chem. 2010 Nov 26; 285(48):37598-606. Webb KJ, Zurita-Lopez CI, Al-Hadid Q, Laganowsky A, Young BD, Lipson RS, Souda P, Faull KF, Whitelegge JP, Clarke SG. PMID: 20864530; PMCID: PMC2988365.
      View in: PubMed   Mentions: 44     Fields:    Translation:AnimalsCells
    63. Identification of protein N-terminal methyltransferases in yeast and humans. Biochemistry. 2010 Jun 29; 49(25):5225-35. Webb KJ, Lipson RS, Al-Hadid Q, Whitelegge JP, Clarke SG. PMID: 20481588; PMCID: PMC2890028.
      View in: PubMed   Mentions: 59     Fields:    Translation:HumansAnimalsCells
    64. Two novel methyltransferases acting upon eukaryotic elongation factor 1A in Saccharomyces cerevisiae. Arch Biochem Biophys. 2010 Aug 15; 500(2):137-43. Lipson RS, Webb KJ, Clarke SG. PMID: 20510667; PMCID: PMC2904425.
      View in: PubMed   Mentions: 31     Fields:    Translation:AnimalsCells
    65. Homocysteine methyltransferases Mht1 and Sam4 prevent the accumulation of age-damaged (R,S)-AdoMet in the yeast Saccharomyces cerevisiae. J Biol Chem. 2010 Jul 02; 285(27):20526-31. Vinci CR, Clarke SG. PMID: 20421295; PMCID: PMC2898356.
      View in: PubMed   Mentions: 11     Fields:    Translation:Animals
    66. TbPRMT6 is a type I protein arginine methyltransferase that contributes to cytokinesis in Trypanosoma brucei. Eukaryot Cell. 2010 Jun; 9(6):866-77. Fisk JC, Zurita-Lopez C, Sayegh J, Tomasello DL, Clarke SG, Read LK. PMID: 20418380; PMCID: PMC2901642.
      View in: PubMed   Mentions: 22     Fields:    Translation:HumansAnimalsCells
    67. Yeast, plants, worms, and flies use a methyltransferase to metabolize age-damaged (R,S)-AdoMet, but what do mammals do? Rejuvenation Res. 2010 Apr-Jun; 13(2-3):362-4. Vinci CR, Clarke SG. PMID: 20370499; PMCID: PMC2946053.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimalsCells
    68. Rmt1 catalyzes zinc-finger independent arginine methylation of ribosomal protein Rps2 in Saccharomyces cerevisiae. Biochem Biophys Res Commun. 2010 Jan 22; 391(4):1658-62. Lipson RS, Webb KJ, Clarke SG. PMID: 20035717; PMCID: PMC2813213.
      View in: PubMed   Mentions: 15     Fields:    Translation:AnimalsCells
    69. Bioinformatic Identification of Novel Methyltransferases. Epigenomics. 2009 Oct 01; 1(1):163-175. Petrossian T, Clarke S. PMID: 20582239; PMCID: PMC2891558.
      View in: PubMed   Mentions: 30     Fields:    
    70. Approaches to measuring the activities of protein arginine N-methyltransferases. Anal Biochem. 2010 Feb 01; 397(1):1-11. Lakowski TM, Zurita-Lopez C, Clarke SG, Frankel A. PMID: 19761747; PMCID: PMC2808438.
      View in: PubMed   Mentions: 6     Fields:    Translation:Cells
    71. Defective responses to oxidative stress in protein l-isoaspartyl repair-deficient Caenorhabditis elegans. Mech Ageing Dev. 2009 Oct; 130(10):670-80. Khare S, Gomez T, Linster CL, Clarke SG. PMID: 19682488; PMCID: PMC2757507.
      View in: PubMed   Mentions: 14     Fields:    Translation:Animals
    72. Multiple Motif Scanning to identify methyltransferases from the yeast proteome. Mol Cell Proteomics. 2009 Jul; 8(7):1516-26. Petrossian TC, Clarke SG. PMID: 19351663; PMCID: PMC2709183.
      View in: PubMed   Mentions: 47     Fields:    Translation:HumansAnimalsCells
    73. A type III protein arginine methyltransferase from the protozoan parasite Trypanosoma brucei. J Biol Chem. 2009 Apr 24; 284(17):11590-600. Fisk JC, Sayegh J, Zurita-Lopez C, Menon S, Presnyak V, Clarke SG, Read LK. PMID: 19254949; PMCID: PMC2670164.
      View in: PubMed   Mentions: 32     Fields:    Translation:HumansAnimalsCells
    74. Protein arginine methylation in mammals: who, what, and why. Mol Cell. 2009 Jan 16; 33(1):1-13. Bedford MT, Clarke SG. PMID: 19150423; PMCID: PMC3372459.
      View in: PubMed   Mentions: 816     Fields:    Translation:AnimalsCells
    75. Identification of two SET domain proteins required for methylation of lysine residues in yeast ribosomal protein Rpl42ab. J Biol Chem. 2008 Dec 19; 283(51):35561-8. Webb KJ, Laganowsky A, Whitelegge JP, Clarke SG. PMID: 18957409; PMCID: PMC2602916.
      View in: PubMed   Mentions: 27     Fields:    Translation:AnimalsCells
    76. The protein L-isoaspartyl-O-methyltransferase functions in the Caenorhabditis elegans stress response. Mech Ageing Dev. 2008 Dec; 129(12):752-8. Gomez TA, Banfield KL, Clarke SG. PMID: 18977240; PMCID: PMC2605584.
      View in: PubMed   Mentions: 6     Fields:    Translation:AnimalsCells
    77. L-Ascorbate biosynthesis in higher plants: the role of VTC2. Trends Plant Sci. 2008 Nov; 13(11):567-73. Linster CL, Clarke SG. PMID: 18824398; PMCID: PMC2583178.
      View in: PubMed   Mentions: 64     Fields:    Translation:Animals
    78. Hsl7 is a substrate-specific type II protein arginine methyltransferase in yeast. Biochem Biophys Res Commun. 2008 Aug 08; 372(4):811-5. Sayegh J, Clarke SG. PMID: 18515076; PMCID: PMC2505109.
      View in: PubMed   Mentions: 15     Fields:    Translation:AnimalsCells
    79. A second GDP-L-galactose phosphorylase in arabidopsis en route to vitamin C. Covalent intermediate and substrate requirements for the conserved reaction. J Biol Chem. 2008 Jul 04; 283(27):18483-92. Linster CL, Adler LN, Webb K, Christensen KC, Brenner C, Clarke SG. PMID: 18463094; PMCID: PMC2441562.
      View in: PubMed   Mentions: 18     Fields:    Translation:AnimalsCells
    80. Chemo-enzymatic detection of protein isoaspartate using protein isoaspartate methyltransferase and hydrazine trapping. Anal Chem. 2008 May 15; 80(10):3882-9. Alfaro JF, Gillies LA, Sun HG, Dai S, Zang T, Klaene JJ, Kim BJ, Lowenson JD, Clarke SG, Karger BL, Zhou ZS. PMID: 18419136.
      View in: PubMed   Mentions: 27     Fields:    
    81. Secreted 3-isopropylmalate methyl ester signals invasive growth during amino acid starvation in Saccharomyces cerevisiae. Biochemistry. 2008 Jan 15; 47(2):698-709. Dumlao DS, Hertz N, Clarke S. PMID: 18092814.
      View in: PubMed   Mentions: 5     Fields:    Translation:AnimalsCells
    82. Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes. Autophagy. 2008 Feb; 4(2):151-75. Klionsky DJ, Abeliovich H, Agostinis P, Agrawal DK, Aliev G, Askew DS, Baba M, Baehrecke EH, Bahr BA, Ballabio A, Bamber BA, Bassham DC, Bergamini E, Bi X, Biard-Piechaczyk M, Blum JS, Bredesen DE, Brodsky JL, Brumell JH, Brunk UT, Bursch W, Camougrand N, Cebollero E, Cecconi F, Chen Y, Chin LS, Choi A, Chu CT, Chung J, Clarke PG, Clark RS, Clarke SG, Clavé C, Cleveland JL, Codogno P, Colombo MI, Coto-Montes A, Cregg JM, Cuervo AM, Debnath J, Demarchi F, Dennis PB, Dennis PA, Deretic V, Devenish RJ, Di Sano F, Dice JF, Difiglia M, Dinesh-Kumar S, Distelhorst CW, Djavaheri-Mergny M, Dorsey FC, Dröge W, Dron M, Dunn WA, Duszenko M, Eissa NT, Elazar Z, Esclatine A, Eskelinen EL, Fésüs L, Finley KD, Fuentes JM, Fueyo J, Fujisaki K, Galliot B, Gao FB, Gewirtz DA, Gibson SB, Gohla A, Goldberg AL, Gonzalez R, González-Estévez C, Gorski S, Gottlieb RA, Häussinger D, He YW, Heidenreich K, Hill JA, Høyer-Hansen M, Hu X, Huang WP, Iwasaki A, Jäättelä M, Jackson WT, Jiang X, Jin S, Johansen T, Jung JU, Kadowaki M, Kang C, Kelekar A, Kessel DH, Kiel JA, Kim HP, Kimchi A, Kinsella TJ, Kiselyov K, Kitamoto K, Knecht E, Komatsu M, Kominami E, Kondo S, Kovács AL, Kroemer G, Kuan CY, Kumar R, Kundu M, Landry J, Laporte M, Le W, Lei HY, Lenardo MJ, Levine B, Lieberman A, Lim KL, Lin FC, Liou W, Liu LF, Lopez-Berestein G, López-Otín C, Lu B, Macleod KF, Malorni W, Martinet W, Matsuoka K, Mautner J, Meijer AJ, Meléndez A, Michels P, Miotto G, Mistiaen WP, Mizushima N, Mograbi B, Monastyrska I, Moore MN, Moreira PI, Moriyasu Y, Motyl T, Münz C, Murphy LO, Naqvi NI, Neufeld TP, Nishino I, Nixon RA, Noda T, Nürnberg B, Ogawa M, Oleinick NL, Olsen LJ, Ozpolat B, Paglin S, Palmer GE, Papassideri I, Parkes M, Perlmutter DH, Perry G, Piacentini M, Pinkas-Kramarski R, Prescott M, Proikas-Cezanne T, Raben N, Rami A, Reggiori F, Rohrer B, Rubinsztein DC, Ryan KM, Sadoshima J, Sakagami H, Sakai Y, Sandri M, Sasakawa C, Sass M, Schneider C, Seglen PO, Seleverstov O, Settleman J, Shacka JJ, Shapiro IM, Sibirny A, Silva-Zacarin EC, Simon HU, Simone C, Simonsen A, Smith MA, Spanel-Borowski K, Srinivas V, Steeves M, Stenmark H, Stromhaug PE, Subauste CS, Sugimoto S, Sulzer D, Suzuki T, Swanson MS, Tabas I, Takeshita F, Talbot NJ, Tallóczy Z, Tanaka K, Tanaka K, Tanida I, Taylor GS, Taylor JP, Terman A, Tettamanti G, Thompson CB, Thumm M, Tolkovsky AM, Tooze SA, Truant R, Tumanovska LV, Uchiyama Y, Ueno T, Uzcátegui NL, van der Klei I, Vaquero EC, Vellai T, Vogel MW, Wang HG, Webster P, Wiley JW, Xi Z, Xiao G, Yahalom J, Yang JM, Yap G, Yin XM, Yoshimori T, Yu L, Yue Z, Yuzaki M, Zabirnyk O, Zheng X, Zhu X, Deter RL. PMID: 18188003; PMCID: PMC2654259.
      View in: PubMed   Mentions: 1202     Fields:    Translation:HumansAnimalsCells
    83. Regulation of protein arginine methyltransferase 8 (PRMT8) activity by its N-terminal domain. J Biol Chem. 2007 Dec 14; 282(50):36444-53. Sayegh J, Webb K, Cheng D, Bedford MT, Clarke SG. PMID: 17925405.
      View in: PubMed   Mentions: 53     Fields:    Translation:HumansCells
    84. S-adenosylmethionine-dependent protein methylation in mammalian cytosol via tyrphostin modification by catechol-O-methyltransferase. J Biol Chem. 2007 Oct 19; 282(42):31094-102. Lipson RS, Clarke SG. PMID: 17724020.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    85. HIV protease inhibitors and nuclear lamin processing: getting the right bells and whistles. Proc Natl Acad Sci U S A. 2007 Aug 28; 104(35):13857-8. Clarke SG. PMID: 17709742; PMCID: PMC1955769.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansAnimalsCells
    86. Autophagy and insulin/TOR signaling in Caenorhabditis elegans pcm-1 protein repair mutants. Autophagy. 2007 Jul-Aug; 3(4):357-9. Gomez TA, Clarke SG. PMID: 17404495.
      View in: PubMed   Mentions: 4     Fields:    Translation:AnimalsCells
    87. 16 Inhibition of mammalian protein methyltransferases by 5'-methylthioadenosine (MTA): A mechanism of action of dietary same? Enzymes. 2006; 24:467-93. Clarke SG. PMID: 26718050.
      View in: PubMed   Mentions: 18     Fields:    
    88. 10 Genetic approaches to understanding the physiologic importance of the carboxyl methylation of isoprenylated proteins. Enzymes. 2006; 24:273-301. Young SG, Clarke SG, Bergoc MO, Phillips M, Fong LG. PMID: 26718044.
      View in: PubMed   Mentions: 3     Fields:    
    89. Arabidopsis VTC2 encodes a GDP-L-galactose phosphorylase, the last unknown enzyme in the Smirnoff-Wheeler pathway to ascorbic acid in plants. J Biol Chem. 2007 Jun 29; 282(26):18879-85. Linster CL, Gomez TA, Christensen KC, Adler LN, Young BD, Brenner C, Clarke SG. PMID: 17462988; PMCID: PMC2556065.
      View in: PubMed   Mentions: 64     Fields:    Translation:AnimalsCells
    90. Yeast ribosomal/cytochrome c SET domain methyltransferase subfamily: identification of Rpl23ab methylation sites and recognition motifs. J Biol Chem. 2007 Apr 27; 282(17):12368-76. Porras-Yakushi TR, Whitelegge JP, Clarke S. PMID: 17327221.
      View in: PubMed   Mentions: 21     Fields:    Translation:HumansAnimalsCells
    91. Recognition of age-damaged (R,S)-adenosyl-L-methionine by two methyltransferases in the yeast Saccharomyces cerevisiae. J Biol Chem. 2007 Mar 23; 282(12):8604-12. Vinci CR, Clarke SG. PMID: 17264075.
      View in: PubMed   Mentions: 15     Fields:    Translation:AnimalsCells
    92. Arabidopsis Protein Repair L-Isoaspartyl Methyltransferases: Predominant Activities at Lethal Temperatures. Physiol Plant. 2006 Dec; 128(4):581-592. Villa ST, Xu Q, Downie AB, Clarke SG. PMID: 21076691; PMCID: PMC2980331.
      View in: PubMed   Mentions: 14     Fields:    
    93. The L-isoaspartyl-O-methyltransferase in Caenorhabditis elegans larval longevity and autophagy. Dev Biol. 2007 Mar 15; 303(2):493-500. Gomez TA, Banfield KL, Trogler DM, Clarke SG. PMID: 17187774; PMCID: PMC1868680.
      View in: PubMed   Mentions: 10     Fields:    Translation:Animals
    94. A novel SET domain methyltransferase in yeast: Rkm2-dependent trimethylation of ribosomal protein L12ab at lysine 10. J Biol Chem. 2006 Nov 24; 281(47):35835-45. Porras-Yakushi TR, Whitelegge JP, Clarke S. PMID: 17005568.
      View in: PubMed   Mentions: 31     Fields:    Translation:AnimalsCells
    95. Yeast Hsl7 (histone synthetic lethal 7) catalyses the in vitro formation of omega-N(G)-monomethylarginine in calf thymus histone H2A. Biochem J. 2006 May 01; 395(3):563-70. Miranda TB, Sayegh J, Frankel A, Katz JE, Miranda M, Clarke S. PMID: 16426232; PMCID: PMC1462694.
      View in: PubMed   Mentions: 16     Fields:    Translation:AnimalsCells
    96. Increased cell proliferation and granule cell number in the dentate gyrus of protein repair-deficient mice. J Comp Neurol. 2005 Dec 26; 493(4):524-37. Farrar CE, Huang CS, Clarke SG, Houser CR. PMID: 16304629.
      View in: PubMed   Mentions: 13     Fields:    Translation:AnimalsCells
    97. Protein arginine methyltransferase 6 specifically methylates the nonhistone chromatin protein HMGA1a. Biochem Biophys Res Commun. 2005 Oct 28; 336(3):831-5. Miranda TB, Webb KJ, Edberg DD, Reeves R, Clarke S. PMID: 16157300.
      View in: PubMed   Mentions: 24     Fields:    Translation:HumansCells
    98. Diet-dependent survival of protein repair-deficient mice. J Nutr Biochem. 2005 Sep; 16(9):554-61. Farrar CE, Clarke S. PMID: 16115544.
      View in: PubMed   Mentions: 4     Fields:    Translation:Animals
    99. A novel methyltransferase required for the formation of the hypermodified nucleoside wybutosine in eucaryotic tRNA. Biochem Biophys Res Commun. 2005 Aug 26; 334(2):433-40. Kalhor HR, Penjwini M, Clarke S. PMID: 16005430.
      View in: PubMed   Mentions: 17     Fields:    Translation:AnimalsCells
    100. A novel SET domain methyltransferase modifies ribosomal protein Rpl23ab in yeast. J Biol Chem. 2005 Oct 14; 280(41):34590-8. Porras-Yakushi TR, Whitelegge JP, Miranda TB, Clarke S. PMID: 16096273.
      View in: PubMed   Mentions: 27     Fields:    Translation:AnimalsCells
    101. A new type of protein methylation activated by tyrphostin A25 and vanadate. FEBS Lett. 2004 Nov 05; 577(1-2):181-6. Miranda TB, Lowenson JD, Clarke S. PMID: 15527782.
      View in: PubMed   Mentions: 5     Fields:    Translation:AnimalsCells
    102. Spliceosome Sm proteins D1, D3, and B/B' are asymmetrically dimethylated at arginine residues in the nucleus. Biochem Biophys Res Commun. 2004 Oct 15; 323(2):382-7. Miranda TB, Khusial P, Cook JR, Lee JH, Gunderson SI, Pestka S, Zieve GW, Clarke S. PMID: 15369763.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansAnimalsCells
    103. A second protein L-isoaspartyl methyltransferase gene in Arabidopsis produces two transcripts whose products are sequestered in the nucleus. Plant Physiol. 2004 Sep; 136(1):2652-64. Xu Q, Belcastro MP, Villa ST, Dinkins RD, Clarke SG, Downie AB. PMID: 15347786; PMCID: PMC523330.
      View in: PubMed   Mentions: 20     Fields:    Translation:AnimalsCells
    104. Improved rotorod performance and hyperactivity in mice deficient in a protein repair methyltransferase. Behav Brain Res. 2004 Aug 12; 153(1):129-41. Vitali R, Clarke S. PMID: 15219714.
      View in: PubMed   Mentions: 16     Fields:    Translation:Animals
    105. PRMT7 is a member of the protein arginine methyltransferase family with a distinct substrate specificity. J Biol Chem. 2004 May 28; 279(22):22902-7. Miranda TB, Miranda M, Frankel A, Clarke S. PMID: 15044439.
      View in: PubMed   Mentions: 79     Fields:    Translation:HumansCells
    106. Fighting cancer by disrupting C-terminal methylation of signaling proteins. J Clin Invest. 2004 Feb; 113(4):513-5. Clarke S, Tamanoi F. PMID: 14966560; PMCID: PMC338270.
      View in: PubMed   Mentions: 14     Fields:    Translation:AnimalsCells
    107. Novel methyltransferase for modified uridine residues at the wobble position of tRNA. Mol Cell Biol. 2003 Dec; 23(24):9283-92. Kalhor HR, Clarke S. PMID: 14645538; PMCID: PMC309612.
      View in: PubMed   Mentions: 88     Fields:    Translation:AnimalsCells
    108. Automated identification of putative methyltransferases from genomic open reading frames. Mol Cell Proteomics. 2003 Aug; 2(8):525-40. Katz JE, Dlakic M, Clarke S. PMID: 12872006.
      View in: PubMed   Mentions: 69     Fields:    Translation:HumansAnimalsCells
    109. Aging as war between chemical and biochemical processes: protein methylation and the recognition of age-damaged proteins for repair. Ageing Res Rev. 2003 Jul; 2(3):263-85. Clarke S. PMID: 12726775.
      View in: PubMed   Mentions: 104     Fields:    Translation:HumansAnimalsCells
    110. Structure and function of an archaeal homolog of survival protein E (SurEalpha): an acid phosphatase with purine nucleotide specificity. J Mol Biol. 2003 Mar 07; 326(5):1559-75. Mura C, Katz JE, Clarke SG, Eisenberg D. PMID: 12595266.
      View in: PubMed   Mentions: 11     Fields:    Translation:Cells
    111. Altered levels of S-adenosylmethionine and S-adenosylhomocysteine in the brains of L-isoaspartyl (D-Aspartyl) O-methyltransferase-deficient mice. J Biol Chem. 2002 Aug 02; 277(31):27856-63. Farrar C, Clarke S. PMID: 12023972.
      View in: PubMed   Mentions: 17     Fields:    Translation:Animals
    112. The methylator meets the terminator. Proc Natl Acad Sci U S A. 2002 Feb 05; 99(3):1104-6. Clarke S. PMID: 11830650; PMCID: PMC122150.
      View in: PubMed   Mentions: 4     Fields:    Translation:Cells
    113. Crystal structure of human L-isoaspartyl methyltransferase. J Biol Chem. 2002 Mar 22; 277(12):10642-6. Ryttersgaard C, Griffith SC, Sawaya MR, MacLaren DC, Clarke S, Yeates TO. PMID: 11792715.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCells
    114. Protein repair methyltransferase from the hyperthermophilic archaeon Pyrococcus furiosus. Unusual methyl-accepting affinity for D-aspartyl and N-succinyl-containing peptides. J Biol Chem. 2002 Jan 11; 277(2):1058-65. Thapar N, Griffith SC, Yeates TO, Clarke S. PMID: 11694513.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
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