Duilio D Cascio

Title(s)Adjunct Professor, Biological Chemistry
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    1. AlphaFold-assisted structure determination of a bacterial protein of unknown function using X-ray and electron crystallography. Acta Crystallogr D Struct Biol. 2024 Apr 01; 80(Pt 4):270-278. Miller JE, Agdanowski MP, Dolinsky JL, Sawaya MR, Cascio D, Rodriguez JA, Yeates TO. PMID: 38451205; PMCID: PMC10994174.
      View in: PubMed   Mentions:
    2. Cryo-EM structures of the D290V mutant of the hnRNPA2 low-complexity domain suggests how D290V affects phase separation and aggregation. J Biol Chem. 2024 Feb; 300(2):105531. Lu J, Ge P, Sawaya MR, Hughes MP, Boyer DR, Cao Q, Abskharon R, Cascio D, Tayeb-Fligelman E, Eisenberg DS. PMID: 38072051; PMCID: PMC10844680.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    3. A Highly Ordered Nitroxide Side Chain for Distance Mapping and Monitoring Slow Structural Fluctuations in Proteins. Appl Magn Reson. 2024; 55(1-3):251-277. Chen M, Kálai T, Cascio D, Bridges MD, Whitelegge JP, Elgeti M, Hubbell WL. PMID: 38357006; PMCID: PMC10861403.
      View in: PubMed   Mentions:
    4. Structure-based design of nanobodies that inhibit seeding of Alzheimer's patient-extracted tau fibrils. Proc Natl Acad Sci U S A. 2023 10 10; 120(41):e2300258120. Abskharon R, Pan H, Sawaya MR, Seidler PM, Olivares EJ, Chen Y, Murray KA, Zhang J, Lantz C, Bentzel M, Boyer DR, Cascio D, Nguyen BA, Hou K, Cheng X, Pardon E, Williams CK, Nana AL, Vinters HV, Spina S, Grinberg LT, Seeley WW, Steyaert J, Glabe CG, Ogorzalek Loo RR, Loo JA, Eisenberg DS. PMID: 37801475; PMCID: PMC10576031.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimalsCells
    5. Development and atomic structure of a new fluorescence-based sensor to probe heme transfer in bacterial pathogens. J Inorg Biochem. 2023 12; 249:112368. Mahoney BJ, Goring AK, Wang Y, Dasika P, Zhou A, Grossbard E, Cascio D, Loo JA, Clubb RT. PMID: 37729854.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    6. Cryo-EM structure determination of small therapeutic protein targets at 3 Å-resolution using a rigid imaging scaffold. Proc Natl Acad Sci U S A. 2023 09 12; 120(37):e2305494120. Castells-Graells R, Meador K, Arbing MA, Sawaya MR, Gee M, Cascio D, Gleave E, Debreczeni JÉ, Breed J, Leopold K, Patel A, Jahagirdar D, Lyons B, Subramaniam S, Phillips C, Yeates TO. PMID: 37669364; PMCID: PMC10500258.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    7. Low complexity domains of the nucleocapsid protein of SARS-CoV-2 form amyloid fibrils. Nat Commun. 2023 04 25; 14(1):2379. Tayeb-Fligelman E, Bowler JT, Tai CE, Sawaya MR, Jiang YX, Garcia G, Griner SL, Cheng X, Salwinski L, Lutter L, Seidler PM, Lu J, Rosenberg GM, Hou K, Abskharon R, Pan H, Zee CT, Boyer DR, Li Y, Anderson DH, Murray KA, Falcon G, Cascio D, Saelices L, Damoiseaux R, Arumugaswami V, Guo F, Eisenberg DS. PMID: 37185252; PMCID: PMC10127185.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    8. The Shr receptor from Streptococcus pyogenes uses a cap and release mechanism to acquire heme-iron from human hemoglobin. Proc Natl Acad Sci U S A. 2023 01 31; 120(5):e2211939120. Macdonald R, Mahoney BJ, Soule J, Goring AK, Ford J, Loo JA, Cascio D, Clubb RT. PMID: 36693107; PMCID: PMC9945957.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    9. Micro-electron diffraction structure of the aggregation-driving N terminus of Drosophila neuronal protein Orb2A reveals amyloid-like β-sheets. J Biol Chem. 2022 10; 298(10):102396. Bowler JT, Sawaya MR, Boyer DR, Cascio D, Bali M, Eisenberg DS. PMID: 35988647; PMCID: PMC9556795.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    10. Cryo-EM structure of RNA-induced tau fibrils reveals a small C-terminal core that may nucleate fibril formation. Proc Natl Acad Sci U S A. 2022 04 12; 119(15):e2119952119. Abskharon R, Sawaya MR, Boyer DR, Cao Q, Nguyen BA, Cascio D, Eisenberg DS. PMID: 35377792; PMCID: PMC9169762.
      View in: PubMed   Mentions: 16     Fields:    Translation:Humans
    11. The structure of the Clostridium thermocellum RsgI9 ectodomain provides insight into the mechanism of biomass sensing. Proteins. 2022 07; 90(7):1457-1467. Mahoney BJ, Takayesu A, Zhou A, Cascio D, Clubb RT. PMID: 35194841; PMCID: PMC9177573.
      View in: PubMed   Mentions: 1     Fields:    Translation:Cells
    12. Insight into the molecular basis of substrate recognition by the wall teichoic acid glycosyltransferase TagA. J Biol Chem. 2022 02; 298(2):101464. Martinez OE, Mahoney BJ, Goring AK, Yi SW, Tran DP, Cascio D, Phillips ML, Muthana MM, Chen X, Jung ME, Loo JA, Clubb RT. PMID: 34864059; PMCID: PMC8784642.
      View in: PubMed   Mentions: 2     Fields:    Translation:Cells
    13. Prospecting for natural products by genome mining and microcrystal electron diffraction. Nat Chem Biol. 2021 08; 17(8):872-877. Kim LJ, Ohashi M, Zhang Z, Tan D, Asay M, Cascio D, Rodriguez JA, Tang Y, Nelson HM. PMID: 34312563; PMCID: PMC8447837.
      View in: PubMed   Mentions: 15     Fields:    Translation:Cells
    14. Structure of human factor VIIa-soluble tissue factor with calcium, magnesium and rubidium. Acta Crystallogr D Struct Biol. 2021 Jun 01; 77(Pt 6):809-819. Vadivel K, Schmidt AE, Cascio D, Padmanabhan K, Krishnaswamy S, Brandstetter H, Bajaj SP. PMID: 34076594; PMCID: PMC8171065.
      View in: PubMed   Mentions: 2  Translation:HumansCells
    15. Isolation and X-ray Crystal Structure of an Electrogenerated TEMPO-N3 Charge-Transfer Complex. Org Lett. 2021 01 15; 23(2):454-458. Nelson HM, Siu JC, Saha A, Cascio D, MacMillan SN, Wu SB, Lu C, Rodríguez JA, Houk KN, Lin S. PMID: 33406362.
      View in: PubMed   Mentions: 5     Fields:    
    16. CryoEM structure of the low-complexity domain of hnRNPA2 and its conversion to pathogenic amyloid. Nat Commun. 2020 08 14; 11(1):4090. Lu J, Cao Q, Hughes MP, Sawaya MR, Boyer DR, Cascio D, Eisenberg DS. PMID: 32796831; PMCID: PMC7427792.
      View in: PubMed   Mentions: 38     Fields:    Translation:Humans
    17. Crystal structure of a conformational antibody that binds tau oligomers and inhibits pathological seeding by extracts from donors with Alzheimer's disease. J Biol Chem. 2020 07 31; 295(31):10662-10676. Abskharon R, Seidler PM, Sawaya MR, Cascio D, Yang TP, Philipp S, Williams CK, Newell KL, Ghetti B, DeTure MA, Dickson DW, Vinters HV, Felgner PL, Nakajima R, Glabe CG, Eisenberg DS. PMID: 32493775; PMCID: PMC7397112.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansCells
    18. Structure-based inhibitors of amyloid beta core suggest a common interface with tau. Elife. 2019 10 15; 8. Griner SL, Seidler P, Bowler J, Murray KA, Yang TP, Sahay S, Sawaya MR, Cascio D, Rodriguez JA, Philipp S, Sosna J, Glabe CG, Gonen T, Eisenberg DS. PMID: 31612856; PMCID: PMC6850776.
      View in: PubMed   Mentions: 39     Fields:    Translation:HumansAnimalsCells
    19. Author Correction: Atomic structures of TDP-43 LCD segments and insights into reversible or pathogenic aggregation. Nat Struct Mol Biol. 2019 Oct; 26(10):988. Guenther EL, Cao Q, Trinh H, Lu J, Sawaya MR, Cascio D, Boyer DR, Rodriguez JA, Hughes MP, Eisenberg DS. PMID: 31530939; PMCID: PMC7103477.
      View in: PubMed   Mentions:    Fields:    
    20. Cooperative DNA binding by proteins through DNA shape complementarity. Nucleic Acids Res. 2019 09 19; 47(16):8874-8887. Hancock SP, Cascio D, Johnson RC. PMID: 31616952; PMCID: PMC7145599.
      View in: PubMed   Mentions: 6     Fields:    Translation:Cells
    21. Structure-based inhibitors halt prion-like seeding by Alzheimer's disease-and tauopathy-derived brain tissue samples. J Biol Chem. 2019 11 01; 294(44):16451-16464. Seidler PM, Boyer DR, Murray KA, Yang TP, Bentzel M, Sawaya MR, Rosenberg G, Cascio D, Williams CK, Newell KL, Ghetti B, DeTure MA, Dickson DW, Vinters HV, Eisenberg DS. PMID: 31537646; PMCID: PMC6827308.
      View in: PubMed   Mentions: 26     Fields:    Translation:HumansCells
    22. Characterization of Reactive Organometallic Species via MicroED. ACS Cent Sci. 2019 Sep 25; 5(9):1507-1513. Jones CG, Asay M, Kim LJ, Kleinsasser JF, Saha A, Fulton TJ, Berkley KR, Cascio D, Malyutin AG, Conley MP, Stoltz BM, Lavallo V, Rodríguez JA, Nelson HM. PMID: 31572777; PMCID: PMC6764211.
      View in: PubMed   Mentions: 13  
    23. Structure of amyloid-β (20-34) with Alzheimer's-associated isomerization at Asp23 reveals a distinct protofilament interface. Nat Commun. 2019 07 26; 10(1):3357. Warmack RA, Boyer DR, Zee CT, Richards LS, Sawaya MR, Cascio D, Gonen T, Eisenberg DS, Clarke SG. PMID: 31350392; PMCID: PMC6659688.
      View in: PubMed   Mentions: 24     Fields:    Translation:HumansCells
    24. Structure and mechanism of TagA, a novel membrane-associated glycosyltransferase that produces wall teichoic acids in pathogenic bacteria. PLoS Pathog. 2019 04; 15(4):e1007723. Kattke MD, Gosschalk JE, Martinez OE, Kumar G, Gale RT, Cascio D, Sawaya MR, Philips M, Brown ED, Clubb RT. PMID: 31002736; PMCID: PMC6493773.
      View in: PubMed   Mentions: 10     Fields:    Translation:Cells
    25. Homochiral and racemic MicroED structures of a peptide repeat from the ice-nucleation protein InaZ. IUCrJ. 2019 Mar 01; 6(Pt 2):197-205. Zee CT, Glynn C, Gallagher-Jones M, Miao J, Santiago CG, Cascio D, Gonen T, Sawaya MR, Rodriguez JA. PMID: 30867917; PMCID: PMC6400192.
      View in: PubMed   Mentions: 9     Fields:    
    26. Structural basis of 7SK RNA 5'-γ-phosphate methylation and retention by MePCE. Nat Chem Biol. 2019 02; 15(2):132-140. Yang Y, Eichhorn CD, Wang Y, Cascio D, Feigon J. PMID: 30559425; PMCID: PMC6339579.
      View in: PubMed   Mentions: 23     Fields:    Translation:HumansCells
    27. The Streptococcus pyogenes Shr protein captures human hemoglobin using two structurally unique binding domains. J Biol Chem. 2018 11 23; 293(47):18365-18377. Macdonald R, Cascio D, Collazo MJ, Phillips M, Clubb RT. PMID: 30301765; PMCID: PMC6254355.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCells
    28. Multiple serine transposase dimers assemble the transposon-end synaptic complex during IS607-family transposition. Elife. 2018 10 05; 7. Chen W, Mandali S, Hancock SP, Kumar P, Collazo M, Cascio D, Johnson RC. PMID: 30289389; PMCID: PMC6188088.
      View in: PubMed   Mentions: 4     Fields:    Translation:Cells
    29. Atomic structures of TDP-43 LCD segments and insights into reversible or pathogenic aggregation. Nat Struct Mol Biol. 2018 06; 25(6):463-471. Guenther EL, Cao Q, Trinh H, Lu J, Sawaya MR, Cascio D, Boyer DR, Rodriguez JA, Hughes MP, Eisenberg DS. PMID: 29786080; PMCID: PMC5990464.
      View in: PubMed   Mentions: 98     Fields:    Translation:HumansCells
    30. Microfocus diffraction from different regions of a protein crystal: structural variations and unit-cell polymorphism. Acta Crystallogr D Struct Biol. 2018 05 01; 74(Pt 5):411-421. Thompson MC, Cascio D, Yeates TO. PMID: 29717712; PMCID: PMC5930349.
      View in: PubMed   Mentions: 6  Translation:Cells
    31. Atomic-level evidence for packing and positional amyloid polymorphism by segment from TDP-43 RRM2. Nat Struct Mol Biol. 2018 04; 25(4):311-319. Guenther EL, Ge P, Trinh H, Sawaya MR, Cascio D, Boyer DR, Gonen T, Zhou ZH, Eisenberg DS. PMID: 29531287; PMCID: PMC6056015.
      View in: PubMed   Mentions: 42     Fields:    Translation:HumansCells
    32. Atomic structures of low-complexity protein segments reveal kinked β sheets that assemble networks. Science. 2018 02 09; 359(6376):698-701. Hughes MP, Sawaya MR, Boyer DR, Goldschmidt L, Rodriguez JA, Cascio D, Chong L, Gonen T, Eisenberg DS. PMID: 29439243; PMCID: PMC6192703.
      View in: PubMed   Mentions: 195     Fields:    Translation:HumansCells
    33. Sub-ångström cryo-EM structure of a prion protofibril reveals a polar clasp. Nat Struct Mol Biol. 2018 02; 25(2):131-134. Gallagher-Jones M, Glynn C, Boyer DR, Martynowycz MW, Hernandez E, Miao J, Zee CT, Novikova IV, Goldschmidt L, McFarlane HT, Helguera GF, Evans JE, Sawaya MR, Cascio D, Eisenberg DS, Gonen T, Rodriguez JA. PMID: 29335561; PMCID: PMC6170007.
      View in: PubMed   Mentions: 43     Fields:    Translation:HumansAnimalsCells
    34. Common fibrillar spines of amyloid-β and human islet amyloid polypeptide revealed by microelectron diffraction and structure-based inhibitors. J Biol Chem. 2018 02 23; 293(8):2888-2902. Krotee P, Griner SL, Sawaya MR, Cascio D, Rodriguez JA, Shi D, Philipp S, Murray K, Saelices L, Lee J, Seidler P, Glabe CG, Jiang L, Gonen T, Eisenberg DS. PMID: 29282295; PMCID: PMC5827424.
      View in: PubMed   Mentions: 30     Fields:    Translation:HumansAnimalsCells
    35. Structure-based inhibitors of tau aggregation. Nat Chem. 2018 02; 10(2):170-176. Seidler PM, Boyer DR, Rodriguez JA, Sawaya MR, Cascio D, Murray K, Gonen T, Eisenberg DS. PMID: 29359764; PMCID: PMC5784779.
      View in: PubMed   Mentions: 116     Fields:    Translation:HumansCells
    36. Crystal structure of Mdm12 and combinatorial reconstitution of Mdm12/Mmm1 ERMES complexes for structural studies. Biochem Biophys Res Commun. 2017 06 17; 488(1):129-135. AhYoung AP, Lu B, Cascio D, Egea PF. PMID: 28479252; PMCID: PMC6061939.
      View in: PubMed   Mentions: 11     Fields:    Translation:AnimalsCells
    37. Atomic structures of fibrillar segments of hIAPP suggest tightly mated β-sheets are important for cytotoxicity. Elife. 2017 01 03; 6. Krotee P, Rodriguez JA, Sawaya MR, Cascio D, Reyes FE, Shi D, Hattne J, Nannenga BL, Oskarsson ME, Philipp S, Griner S, Jiang L, Glabe CG, Westermark GT, Gonen T, Eisenberg DS. PMID: 28045370; PMCID: PMC5207774.
      View in: PubMed   Mentions: 56     Fields:    Translation:HumansCells
    38. Crystal Structure of the Streptomyces coelicolor Sortase E1 Transpeptidase Provides Insight into the Binding Mode of the Novel Class E Sorting Signal. PLoS One. 2016; 11(12):e0167763. Kattke MD, Chan AH, Duong A, Sexton DL, Sawaya MR, Cascio D, Elliot MA, Clubb RT. PMID: 27936128; PMCID: PMC5148588.
      View in: PubMed   Mentions: 13     Fields:    Translation:Cells
    39. Crystal structure of the toxin Msmeg_6760, the structural homolog of Mycobacterium tuberculosis Rv2035, a novel type II toxin involved in the hypoxic response. Acta Crystallogr F Struct Biol Commun. 2016 12 01; 72(Pt 12):863-869. Bajaj RA, Arbing MA, Shin A, Cascio D, Miallau L. PMID: 27917833; PMCID: PMC5137462.
      View in: PubMed   Mentions: 3     Fields:    Translation:Cells
    40. Characterization of WY 14,643 and its Complex with Aldose Reductase. Sci Rep. 2016 10 10; 6:34394. Sawaya MR, Verma M, Balendiran V, Rath NP, Cascio D, Balendiran GK. PMID: 27721416; PMCID: PMC5056380.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    41. Ab initio structure determination from prion nanocrystals at atomic resolution by MicroED. Proc Natl Acad Sci U S A. 2016 10 04; 113(40):11232-11236. Sawaya MR, Rodriguez J, Cascio D, Collazo MJ, Shi D, Reyes FE, Hattne J, Gonen T, Eisenberg DS. PMID: 27647903; PMCID: PMC5056061.
      View in: PubMed   Mentions: 59     Fields:    Translation:Cells
    42. A PII-Like Protein Regulated by Bicarbonate: Structural and Biochemical Studies of the Carboxysome-Associated CPII Protein. J Mol Biol. 2016 10 09; 428(20):4013-4030. Wheatley NM, Eden KD, Ngo J, Rosinski JS, Sawaya MR, Cascio D, Collazo M, Hoveida H, Hubbell WL, Yeates TO. PMID: 27464895; PMCID: PMC5048545.
      View in: PubMed   Mentions: 5     Fields:    Translation:Cells
    43. DNA Sequence Determinants Controlling Affinity, Stability and Shape of DNA Complexes Bound by the Nucleoid Protein Fis. PLoS One. 2016; 11(3):e0150189. Hancock SP, Stella S, Cascio D, Johnson RC. PMID: 26959646; PMCID: PMC4784862.
      View in: PubMed   Mentions: 23     Fields:    Translation:Cells
    44. Structure of a putative ClpS N-end rule adaptor protein from the malaria pathogen Plasmodium falciparum. Protein Sci. 2016 Mar; 25(3):689-701. AhYoung AP, Koehl A, Vizcarra CL, Cascio D, Egea PF. PMID: 26701219; PMCID: PMC4815404.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansAnimalsCells
    45. Origins of stereoselectivity in evolved ketoreductases. Proc Natl Acad Sci U S A. 2015 Dec 22; 112(51):E7065-72. Noey EL, Tibrewal N, Jiménez-Osés G, Osuna S, Park J, Bond CM, Cascio D, Liang J, Zhang X, Huisman GW, Tang Y, Houk KN. PMID: 26644568; PMCID: PMC4697376.
      View in: PubMed   Mentions: 21     Fields:    Translation:Cells
    46. Inhibition by small-molecule ligands of formation of amyloid fibrils of an immunoglobulin light chain variable domain. Elife. 2015 Nov 18; 4:e10935. Brumshtein B, Esswein SR, Salwinski L, Phillips ML, Ly AT, Cascio D, Sawaya MR, Eisenberg DS. PMID: 26576950; PMCID: PMC4758944.
      View in: PubMed   Mentions: 22     Fields:    
    47. Structure of Tetrahymena telomerase reveals previously unknown subunits, functions, and interactions. Science. 2015 Oct 30; 350(6260):aab4070. Jiang J, Chan H, Cash DD, Miracco EJ, Ogorzalek Loo RR, Upton HE, Cascio D, O'Brien Johnson R, Collins K, Loo JA, Zhou ZH, Feigon J. PMID: 26472759; PMCID: PMC4687456.
      View in: PubMed   Mentions: 91     Fields:    Translation:AnimalsCells
    48. Uncovering the Mechanism of Aggregation of Human Transthyretin. J Biol Chem. 2015 Nov 27; 290(48):28932-43. Saelices L, Johnson LM, Liang WY, Sawaya MR, Cascio D, Ruchala P, Whitelegge J, Jiang L, Riek R, Eisenberg DS. PMID: 26459562; PMCID: PMC4661406.
      View in: PubMed   Mentions: 64     Fields:    Translation:HumansCells
    49. Structure of the toxic core of α-synuclein from invisible crystals. Nature. 2015 Sep 24; 525(7570):486-90. Rodriguez JA, Ivanova MI, Sawaya MR, Cascio D, Reyes FE, Shi D, Sangwan S, Guenther EL, Johnson LM, Zhang M, Jiang L, Arbing MA, Nannenga BL, Hattne J, Whitelegge J, Brewster AS, Messerschmidt M, Boutet S, Sauter NK, Gonen T, Eisenberg DS. PMID: 26352473; PMCID: PMC4791177.
      View in: PubMed   Mentions: 271     Fields:    Translation:HumansCells
    50. Biochemical and Structural Basis for Controlling Chemical Modularity in Fungal Polyketide Biosynthesis. J Am Chem Soc. 2015 Aug 12; 137(31):9885-93. Winter JM, Cascio D, Dietrich D, Sato M, Watanabe K, Sawaya MR, Vederas JC, Tang Y. PMID: 26172141; PMCID: PMC4922798.
      View in: PubMed   Mentions: 23     Fields:    Translation:AnimalsCells
    51. Structural mapping of the ClpB ATPases of Plasmodium falciparum: Targeting protein folding and secretion for antimalarial drug design. Protein Sci. 2015 Sep; 24(9):1508-20. AhYoung AP, Koehl A, Cascio D, Egea PF. PMID: 26130467; PMCID: PMC4570544.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansAnimalsCells
    52. An allosteric model for control of pore opening by substrate binding in the EutL microcompartment shell protein. Protein Sci. 2015 Jun; 24(6):956-75. Thompson MC, Cascio D, Leibly DJ, Yeates TO. PMID: 25752492; PMCID: PMC4456109.
      View in: PubMed   Mentions: 20     Fields:    Translation:Cells
    53. Toxicity of eosinophil MBP is repressed by intracellular crystallization and promoted by extracellular aggregation. Mol Cell. 2015 Mar 19; 57(6):1011-1021. Soragni A, Yousefi S, Stoeckle C, Soriaga AB, Sawaya MR, Kozlowski E, Schmid I, Radonjic-Hoesli S, Boutet S, Williams GJ, Messerschmidt M, Seibert MM, Cascio D, Zatsepin NA, Burghammer M, Riekel C, Colletier JP, Riek R, Eisenberg DS, Simon HU. PMID: 25728769; PMCID: PMC4904734.
      View in: PubMed   Mentions: 44     Fields:    Translation:HumansAnimalsCells
    54. Structure and interactions of the CS domain of human H/ACA RNP assembly protein Shq1. J Mol Biol. 2015 Feb 27; 427(4):807-823. Singh M, Wang Z, Cascio D, Feigon J. PMID: 25553844; PMCID: PMC4323627.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansAnimalsCells
    55. Crystal structure and solution characterization of the thioredoxin-2 from Plasmodium falciparum, a constituent of an essential parasitic protein export complex. Biochem Biophys Res Commun. 2015 Jan 02; 456(1):403-9. Peng M, Cascio D, Egea PF. PMID: 25475729; PMCID: PMC5023060.
      View in: PubMed   Mentions: 10     Fields:    Translation:AnimalsCells
    56. Formation of amyloid fibers by monomeric light chain variable domains. J Biol Chem. 2014 Oct 03; 289(40):27513-25. Brumshtein B, Esswein SR, Landau M, Ryan CM, Whitelegge JP, Phillips ML, Cascio D, Sawaya MR, Eisenberg DS. PMID: 25138218; PMCID: PMC4183792.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansCells
    57. Protein crystal structure obtained at 2.9 Å resolution from injecting bacterial cells into an X-ray free-electron laser beam. Proc Natl Acad Sci U S A. 2014 Sep 02; 111(35):12769-74. Sawaya MR, Cascio D, Gingery M, Rodriguez J, Goldschmidt L, Colletier JP, Messerschmidt MM, Boutet S, Koglin JE, Williams GJ, Brewster AS, Nass K, Hattne J, Botha S, Doak RB, Shoeman RL, DePonte DP, Park HW, Federici BA, Sauter NK, Schlichting I, Eisenberg DS. PMID: 25136092; PMCID: PMC4156696.
      View in: PubMed   Mentions: 51     Fields:    Translation:Cells
    58. Heterologous expression of mycobacterial Esx complexes in Escherichia coli for structural studies is facilitated by the use of maltose binding protein fusions. PLoS One. 2013; 8(11):e81753. Arbing MA, Chan S, Harris L, Kuo E, Zhou TT, Ahn CJ, Nguyen L, He Q, Lu J, Menchavez PT, Shin A, Holton T, Sawaya MR, Cascio D, Eisenberg D. PMID: 24312350; PMCID: PMC3843698.
      View in: PubMed   Mentions: 14     Fields:    Translation:Cells
    59. Control of DNA minor groove width and Fis protein binding by the purine 2-amino group. Nucleic Acids Res. 2013 Jul; 41(13):6750-60. Hancock SP, Ghane T, Cascio D, Rohs R, Di Felice R, Johnson RC. PMID: 23661683; PMCID: PMC3711457.
      View in: PubMed   Mentions: 47     Fields:    Translation:Cells
    60. Tetramerization reinforces the dimer interface of MnSOD. PLoS One. 2013; 8(5):e62446. Sheng Y, Durazo A, Schumacher M, Gralla EB, Cascio D, Cabelli DE, Valentine JS. PMID: 23667478; PMCID: PMC3646814.
      View in: PubMed   Mentions: 9     Fields:    Translation:AnimalsCells
    61. Structure and dynamics of an imidazoline nitroxide side chain with strongly hindered internal motion in proteins. J Magn Reson. 2013 Jul; 232:53-61. Toledo Warshaviak D, Khramtsov VV, Cascio D, Altenbach C, Hubbell WL. PMID: 23694751; PMCID: PMC3758229.
      View in: PubMed   Mentions: 26     Fields:    Translation:Cells
    62. Bacterial microcompartment shells of diverse functional types possess pentameric vertex proteins. Protein Sci. 2013 May; 22(5):660-5. Wheatley NM, Gidaniyan SD, Liu Y, Cascio D, Yeates TO. PMID: 23456886; PMCID: PMC3649267.
      View in: PubMed   Mentions: 43     Fields:    Translation:Cells
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