Alexander V Pushkin

Title(s)Adjunct Professor, Medicine
SchoolMedicine
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    Collapse Research 
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    Biology of Mercapturic Acid Mediated Nephrotoxicity
    NIH R01ES012935Jul 25, 2005 - Apr 30, 2010
    Role: Principal Investigator

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    1. Molecular dynamics simulations of lipid-protein interactions in SLC4 proteins. Biophys J. 2024 Jun 18; 123(12):1705-1721. Zhekova HR, Ramirez Echemendía DP, Sejdiu BI, Pushkin A, Tieleman DP, Kurtz I. PMID: 38760929; PMCID: PMC11214021.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    2. Coarse-grained molecular dynamics simulations of lipid-protein interactions in SLC4 proteins. bioRxiv. 2023 Jun 28. Zhekova HR, Ramirez-Echemendía DP, Sejdiu BI, Pushkin A, Tieleman DP, Kurtz I. PMID: 37425774; PMCID: PMC10327080.
      View in: PubMed   Mentions:
    3. CryoEM structures of anion exchanger 1 capture multiple states of inward- and outward-facing conformations. Commun Biol. 2022 12 14; 5(1):1372. Zhekova HR, Jiang J, Wang W, Tsirulnikov K, Kayik G, Khan HM, Azimov R, Abuladze N, Kao L, Newman D, Noskov SY, Tieleman DP, Hong Zhou Z, Pushkin A, Kurtz I. PMID: 36517642; PMCID: PMC9751308.
      View in: PubMed   Mentions: 11  Translation:AnimalsCells
    4. Publisher Correction: Cryo-EM structure of the sodium-driven chloride/bicarbonate exchanger NDCBE. Nat Commun. 2021 Oct 13; 12(1):6083. Wang W, Tsirulnikov K, Zhekova HR, Kayik G, Khan HM, Azimov R, Abuladze N, Kao L, Newman D, Noskov SY, Zhou ZH, Pushkin A, Kurtz I. PMID: 34645810; PMCID: PMC8514430.
      View in: PubMed   Mentions: 1     Fields:    
    5. Cryo-EM structure of the sodium-driven chloride/bicarbonate exchanger NDCBE. Nat Commun. 2021 09 28; 12(1):5690. Wang W, Tsirulnikov K, Zhekova HR, Kayik G, Khan HM, Azimov R, Abuladze N, Kao L, Newman D, Noskov SY, Zhou ZH, Pushkin A, Kurtz I. PMID: 34584093; PMCID: PMC8478935.
      View in: PubMed   Mentions: 22     Fields:    Translation:HumansCells
    6. Identification of multiple substrate binding sites in SLC4 transporters in the outward-facing conformation: Insights into the transport mechanism. J Biol Chem. 2021 Jan-Jun; 296:100724. Zhekova HR, Pushkin A, Kayik G, Kao L, Azimov R, Abuladze N, Kurtz D, Damergi M, Noskov SY, Kurtz I. PMID: 33932403; PMCID: PMC8191340.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCells
    7. SLC4A11 function: evidence for H+(OH-) and NH3-H+ transport. Am J Physiol Cell Physiol. 2020 02 01; 318(2):C392-C405. Kao L, Azimov R, Shao XM, Abuladze N, Newman D, Zhekova H, Noskov S, Pushkin A, Kurtz I. PMID: 31774702; PMCID: PMC7052617.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansCells
    8. CryoEM structure of the human SLC4A4 sodium-coupled acid-base transporter NBCe1. Nat Commun. 2018 03 02; 9(1):900. Huynh KW, Jiang J, Abuladze N, Tsirulnikov K, Kao L, Shao X, Newman D, Azimov R, Pushkin A, Zhou ZH, Kurtz I. PMID: 29500354; PMCID: PMC5834491.
      View in: PubMed   Mentions: 51     Fields:    Translation:HumansCells
    9. Aminoacylase 3 Is a New Potential Marker and Therapeutic Target in Hepatocellular Carcinoma. J Cancer. 2018; 9(1):1-12. Tsirulnikov K, Duarte S, Ray A, Datta N, Zarrinpar A, Hwang L, Faull K, Pushkin A, Kurtz I. PMID: 29290764; PMCID: PMC5743706.
      View in: PubMed   Mentions: 2  
    10. Single particle electron microscopy analysis of the bovine anion exchanger 1 reveals a flexible linker connecting the cytoplasmic and membrane domains. PLoS One. 2013; 8(2):e55408. Jiang J, Magilnick N, Tsirulnikov K, Abuladze N, Atanasov I, Ge P, Narla M, Pushkin A, Zhou ZH, Kurtz I. PMID: 23393575; PMCID: PMC3564912.
      View in: PubMed   Mentions: 14     Fields:    Translation:AnimalsCells
    11. Aminoacylase 3 binds to and cleaves the N-terminus of the hepatitis C virus core protein. FEBS Lett. 2012 Nov 02; 586(21):3799-804. Tsirulnikov K, Abuladze N, Vahi R, Hasnain H, Phillips M, Ryan CM, Atanasov I, Faull KF, Kurtz I, Pushkin A. PMID: 23010594; PMCID: PMC3483449.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    12. Inhibition of aminoacylase 3 protects rat brain cortex neuronal cells from the toxicity of 4-hydroxy-2-nonenal mercapturate and 4-hydroxy-2-nonenal. Toxicol Appl Pharmacol. 2012 Sep 15; 263(3):303-14. Tsirulnikov K, Abuladze N, Bragin A, Faull K, Cascio D, Damoiseaux R, Schibler MJ, Pushkin A. PMID: 22819785; PMCID: PMC5575769.
      View in: PubMed   Mentions: 9     Fields:    Translation:AnimalsCells
    13. Structures of aminoacylase 3 in complex with acetylated substrates. Proc Natl Acad Sci U S A. 2010 Oct 19; 107(42):17962-7. Hsieh JM, Tsirulnikov K, Sawaya MR, Magilnick N, Abuladze N, Kurtz I, Abramson J, Pushkin A. PMID: 20921362; PMCID: PMC2964198.
      View in: PubMed   Mentions: 5     Fields:    Translation:AnimalsCells
    14. Structural and functional characterization of the C-terminal transmembrane region of NBCe1-A. J Biol Chem. 2010 Nov 26; 285(48):37178-87. Zhu Q, Kao L, Azimov R, Abuladze N, Newman D, Pushkin A, Liu W, Chang C, Kurtz I. PMID: 20837482; PMCID: PMC2988324.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansCells
    15. Topological location and structural importance of the NBCe1-A residues mutated in proximal renal tubular acidosis. J Biol Chem. 2010 Apr 30; 285(18):13416-26. Zhu Q, Kao L, Azimov R, Newman D, Liu W, Pushkin A, Abuladze N, Kurtz I. PMID: 20197274; PMCID: PMC2859501.
      View in: PubMed   Mentions: 30     Fields:    Translation:HumansCells
    16. Transport of N-acetyl-S-(1,2-dichlorovinyl)-L-cysteine, a metabolite of trichloroethylene, by mouse multidrug resistance associated protein 2 (Mrp2). Toxicol Appl Pharmacol. 2010 Apr 15; 244(2):218-25. Tsirulnikov K, Abuladze N, Koag MC, Newman D, Scholz K, Bondar G, Zhu Q, Avliyakulov NK, Dekant W, Faull K, Kurtz I, Pushkin A. PMID: 20060011; PMCID: PMC2847015.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    17. Slc4a11 gene disruption in mice: cellular targets of sensorineuronal abnormalities. J Biol Chem. 2009 Sep 25; 284(39):26882-96. Lopez IA, Rosenblatt MI, Kim C, Galbraith GC, Jones SM, Kao L, Newman D, Liu W, Yeh S, Pushkin A, Abuladze N, Kurtz I. PMID: 19586905; PMCID: PMC2785376.
      View in: PubMed   Mentions: 43     Fields:    Translation:HumansAnimalsCells
    18. Mouse aminoacylase 3: a metalloenzyme activated by cobalt and nickel. Biochim Biophys Acta. 2009 Jul; 1794(7):1049-57. Tsirulnikov K, Abuladze N, Newman D, Ryazantsev S, Wolak T, Magilnick N, Koag MC, Kurtz I, Pushkin A. PMID: 19362172; PMCID: PMC2735877.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansAnimalsCells
    19. NBCe1-A Transmembrane Segment 1 Lines the Ion Translocation Pathway. J Biol Chem. 2009 Mar 27; 284(13):8918-29. Zhu Q, Azimov R, Kao L, Newman D, Liu W, Abuladze N, Pushkin A, Kurtz I. PMID: 19158093; PMCID: PMC2659249.
      View in: PubMed   Mentions: 22     Fields:    Translation:HumansCells
    20. Oligomeric structure and minimal functional unit of the electrogenic sodium bicarbonate cotransporter NBCe1-A. J Biol Chem. 2008 Sep 26; 283(39):26782-94. Kao L, Sassani P, Azimov R, Pushkin A, Abuladze N, Peti-Peterdi J, Liu W, Newman D, Kurtz I. PMID: 18658147; PMCID: PMC2546552.
      View in: PubMed   Mentions: 43     Fields:    Translation:HumansAnimalsCells
    21. G418-mediated ribosomal read-through of a nonsense mutation causing autosomal recessive proximal renal tubular acidosis. Am J Physiol Renal Physiol. 2008 Sep; 295(3):F633-41. Azimov R, Abuladze N, Sassani P, Newman D, Kao L, Liu W, Orozco N, Ruchala P, Pushkin A, Kurtz I. PMID: 18614622; PMCID: PMC2653109.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCells
    22. Measurement of aminoacylases. Curr Protoc Toxicol. 2008 Feb; Chapter 6:Unit6.14. Pushkin A, Kurtz I. PMID: 23045009.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    23. Structural characterization of dimeric murine aminoacylase III. FEBS Lett. 2007 May 01; 581(9):1898-902. Ryazantsev S, Abuladze N, Newman D, Bondar G, Kurtz I, Pushkin A. PMID: 17434493.
      View in: PubMed   Mentions: 7     Fields:    Translation:AnimalsCells
    24. Specificity of aminoacylase III-mediated deacetylation of mercapturic acids. Drug Metab Dispos. 2007 Jan; 35(1):43-50. Newman D, Abuladze N, Scholz K, Dekant W, Tsuprun V, Ryazantsev S, Bondar G, Sassani P, Kurtz I, Pushkin A. PMID: 17012540.
      View in: PubMed   Mentions: 14     Fields:    Translation:AnimalsCells
    25. SLC4 base (HCO3 -, CO3 2-) transporters: classification, function, structure, genetic diseases, and knockout models. Am J Physiol Renal Physiol. 2006 Mar; 290(3):F580-99. Pushkin A, Kurtz I. PMID: 16461757.
      View in: PubMed   Mentions: 74     Fields:    Translation:HumansAnimalsCells
    26. Critical amino acid residues involved in the electrogenic sodium-bicarbonate cotransporter kNBC1-mediated transport. J Physiol. 2005 Jun 15; 565(Pt 3):717-30. Abuladze N, Azimov R, Newman D, Sassani P, Liu W, Tatishchev S, Pushkin A, Kurtz I. PMID: 15817634; PMCID: PMC1464572.
      View in: PubMed   Mentions: 24     Fields:    Translation:HumansCells
    27. Molecular mechanism of kNBC1-carbonic anhydrase II interaction in proximal tubule cells. J Physiol. 2004 Aug 15; 559(Pt 1):55-65. Pushkin A, Abuladze N, Gross E, Newman D, Tatishchev S, Lee I, Fedotoff O, Bondar G, Azimov R, Ngyuen M, Kurtz I. PMID: 15218065; PMCID: PMC1665076.
      View in: PubMed   Mentions: 38     Fields:    Translation:HumansAnimalsCells
    28. Expression and localization of rat NBC4c in liver and renal uroepithelium. Am J Physiol Cell Physiol. 2004 Sep; 287(3):C781-9. Abuladze N, Pushkin A, Tatishchev S, Newman D, Sassani P, Kurtz I. PMID: 15151908.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansAnimalsCells
    29. Structural characterization, tissue distribution, and functional expression of murine aminoacylase III. Am J Physiol Cell Physiol. 2004 Apr; 286(4):C848-56. Pushkin A, Carpenito G, Abuladze N, Newman D, Tsuprun V, Ryazantsev S, Motemoturu S, Sassani P, Solovieva N, Dukkipati R, Kurtz I. PMID: 14656720.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansAnimalsCells
    30. Blindness and auditory impairment caused by loss of the sodium bicarbonate cotransporter NBC3. Nat Genet. 2003 Jul; 34(3):313-9. Bok D, Galbraith G, Lopez I, Woodruff M, Nusinowitz S, BeltrandelRio H, Huang W, Zhao S, Geske R, Montgomery C, Van Sligtenhorst I, Friddle C, Platt K, Sparks MJ, Pushkin A, Abuladze N, Ishiyama A, Dukkipati R, Liu W, Kurtz I. PMID: 12808454.
      View in: PubMed   Mentions: 53     Fields:    Translation:AnimalsCells
    31. Identification of membrane topography of the electrogenic sodium bicarbonate cotransporter pNBC1 by in vitro transcription/translation. Biochemistry. 2003 Jan 28; 42(3):755-65. Tatishchev S, Abuladze N, Pushkin A, Newman D, Liu W, Weeks D, Sachs G, Kurtz I. PMID: 12534288.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansAnimalsCells
    32. The COOH termini of NBC3 and the 56-kDa H+-ATPase subunit are PDZ motifs involved in their interaction. Am J Physiol Cell Physiol. 2003 Mar; 284(3):C667-73. Pushkin A, Abuladze N, Newman D, Muronets V, Sassani P, Tatishchev S, Kurtz I. PMID: 12444018.
      View in: PubMed   Mentions: 18     Fields:    Translation:AnimalsCells
    33. Regulation of the sodium bicarbonate cotransporter kNBC1 function: role of Asp(986), Asp(988) and kNBC1-carbonic anhydrase II binding. J Physiol. 2002 11 01; 544(3):679-85. Gross E, Pushkin A, Abuladze N, Fedotoff O, Kurtz I. PMID: 12411514; PMCID: PMC2290621.
      View in: PubMed   Mentions: 35     Fields:    Translation:AnimalsCells
    34. The cystic fibrosis transmembrane conductance regulator interacts with and regulates the activity of the HCO3- salvage transporter human Na+-HCO3- cotransport isoform 3. J Biol Chem. 2002 Dec 27; 277(52):50503-9. Park M, Ko SB, Choi JY, Muallem G, Thomas PJ, Pushkin A, Lee MS, Kim JY, Lee MG, Muallem S, Kurtz I. PMID: 12403779.
      View in: PubMed   Mentions: 37     Fields:    Translation:HumansCells
    35. Functional characterization of NBC4: a new electrogenic sodium-bicarbonate cotransporter. Am J Physiol Cell Physiol. 2002 Feb; 282(2):C408-16. Sassani P, Pushkin A, Gross E, Gomer A, Abuladze N, Dukkipati R, Carpenito G, Kurtz I. PMID: 11788353.
      View in: PubMed   Mentions: 47     Fields:    Translation:HumansCells
    36. Genomic organization of the DCTN1-SLC4A5 locus encoding both NBC4 and p150(Glued). Cytogenet Cell Genet. 2001; 95(3-4):163-8. Pushkin A, Abuladze N, Newman D, Tatishchev S, Kurtz I. PMID: 12063394.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    37. Oligomeric structure of bAE3 protein. IUBMB Life. 2000 Dec; 50(6):397-401. Pushkin AV, Tsuprun VL, Abuladze NK, Newman D, Kurtz I. PMID: 11327314.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    38. Two C-terminal variants of NBC4, a new member of the sodium bicarbonate cotransporter family: cloning, characterization, and localization. IUBMB Life. 2000 Jul; 50(1):13-9. Pushkin A, Abuladze N, Newman D, Lee I, Xu G, Kurtz I. PMID: 11087115.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansCells
    39. Electron microscopy and image analysis of the GroEL-like protein and its complexes with glutamine synthetase from pea leaves. Biochim Biophys Acta. 1992 Jan 30; 1099(1):67-73. Tsuprun VL, Boekema EJ, Pushkin AV, Tagunova IV. PMID: 1346750.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    40. Electron microscopy of the complexes of ribulose-1,5-bisphosphate carboxylase (Rubisco) and Rubisco subunit-binding protein from pea leaves. FEBS Lett. 1991 Sep 09; 289(2):205-9. Tsuprun VL, Boekema EJ, Samsonidze TG, Pushkin AV. PMID: 1915848.
      View in: PubMed   Mentions: 4     Fields:    Translation:Animals
    41. [High molecular weight protein consisting of 14 monomers from pea leaves]. Biokhimiia. 1983 Sep; 48(9):1441-6. Pushkin AV, Tsuprun VL, Solov'eva NA, Shubin VV, Evstigneeva ZG. PMID: 6626605.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    42. Effect of light on the formation of multiple molecular forms of glutamine synthetase in plants. Mol Cell Biochem. 1981 Oct 30; 40(2):123-5. Evstigneeva ZG, Pushkin AV, Solovieva NA, Golova TV, Kretovich WL. PMID: 6118828.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    43. Electron microscopy of glutamine synthetase from pea leaf chloroplasts. Biochim Biophys Acta. 1980 Nov 20; 626(1):1-4. Tsuprun VL, Samsonidze TG, Radukina NA, Pushkin AV, Evstigneeva ZG, Kretovich WL. PMID: 6109548.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
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