Alexander V Pushkin

Title(s)Adjunct Professor, Medicine
SchoolMedicine
Address
vCardDownload vCard

    Collapse Research 
    Collapse Research Activities and Funding
    Biology of Mercapturic Acid Mediated Nephrotoxicity
    NIH R01ES012935Jul 25, 2005 - Apr 30, 2010
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
    Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Identification of multiple substrate binding sites in SLC4 transporters in the outward-facing conformation: insights into the transport mechanism. J Biol Chem. 2021 Apr 28; 100724. Zhekova HR, Pushkin A, Kayik G, Kao L, Azimov R, Abuladze N, Kurtz D, Damergi M, Noskov S, Kurtz I. PMID: 33932403.
      View in: PubMed   Mentions:    Fields:    
    2. SLC4A11 function: evidence for H+(OH-) and NH3-H+ transport. Am J Physiol Cell Physiol. 2020 02 01; 318(2):C392-C405. Kao L, Azimov R, Shao XM, Abuladze N, Newman D, Zhekova H, Noskov S, Pushkin A, Kurtz I. PMID: 31774702.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    3. CryoEM structure of the human SLC4A4 sodium-coupled acid-base transporter NBCe1. Nat Commun. 2018 03 02; 9(1):900. Huynh KW, Jiang J, Abuladze N, Tsirulnikov K, Kao L, Shao X, Newman D, Azimov R, Pushkin A, Zhou ZH, Kurtz I. PMID: 29500354.
      View in: PubMed   Mentions: 21     Fields:    Translation:HumansCells
    4. Aminoacylase 3 Is a New Potential Marker and Therapeutic Target in Hepatocellular Carcinoma. J Cancer. 2018; 9(1):1-12. Tsirulnikov K, Duarte S, Ray A, Datta N, Zarrinpar A, Hwang L, Faull K, Pushkin A, Kurtz I. PMID: 29290764.
      View in: PubMed   Mentions:
    5. Single particle electron microscopy analysis of the bovine anion exchanger 1 reveals a flexible linker connecting the cytoplasmic and membrane domains. PLoS One. 2013; 8(2):e55408. Jiang J, Magilnick N, Tsirulnikov K, Abuladze N, Atanasov I, Ge P, Narla M, Pushkin A, Zhou ZH, Kurtz I. PMID: 23393575.
      View in: PubMed   Mentions: 10     Fields:    Translation:AnimalsCells
    6. Aminoacylase 3 binds to and cleaves the N-terminus of the hepatitis C virus core protein. FEBS Lett. 2012 Nov 02; 586(21):3799-804. Tsirulnikov K, Abuladze N, Vahi R, Hasnain H, Phillips M, Ryan CM, Atanasov I, Faull KF, Kurtz I, Pushkin A. PMID: 23010594.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    7. Inhibition of aminoacylase 3 protects rat brain cortex neuronal cells from the toxicity of 4-hydroxy-2-nonenal mercapturate and 4-hydroxy-2-nonenal. Toxicol Appl Pharmacol. 2012 Sep 15; 263(3):303-14. Tsirulnikov K, Abuladze N, Bragin A, Faull K, Cascio D, Damoiseaux R, Schibler MJ, Pushkin A. PMID: 22819785.
      View in: PubMed   Mentions: 8     Fields:    Translation:AnimalsCells
    8. Structures of aminoacylase 3 in complex with acetylated substrates. Proc Natl Acad Sci U S A. 2010 Oct 19; 107(42):17962-7. Hsieh JM, Tsirulnikov K, Sawaya MR, Magilnick N, Abuladze N, Kurtz I, Abramson J, Pushkin A. PMID: 20921362.
      View in: PubMed   Mentions: 5     Fields:    Translation:AnimalsCells
    9. Structural and functional characterization of the C-terminal transmembrane region of NBCe1-A. J Biol Chem. 2010 Nov 26; 285(48):37178-87. Zhu Q, Kao L, Azimov R, Abuladze N, Newman D, Pushkin A, Liu W, Chang C, Kurtz I. PMID: 20837482.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansCells
    10. Topological location and structural importance of the NBCe1-A residues mutated in proximal renal tubular acidosis. J Biol Chem. 2010 Apr 30; 285(18):13416-26. Zhu Q, Kao L, Azimov R, Newman D, Liu W, Pushkin A, Abuladze N, Kurtz I. PMID: 20197274.
      View in: PubMed   Mentions: 28     Fields:    Translation:HumansCells
    11. Transport of N-acetyl-S-(1,2-dichlorovinyl)-L-cysteine, a metabolite of trichloroethylene, by mouse multidrug resistance associated protein 2 (Mrp2). Toxicol Appl Pharmacol. 2010 Apr 15; 244(2):218-25. Tsirulnikov K, Abuladze N, Koag MC, Newman D, Scholz K, Bondar G, Zhu Q, Avliyakulov NK, Dekant W, Faull K, Kurtz I, Pushkin A. PMID: 20060011.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    12. Slc4a11 gene disruption in mice: cellular targets of sensorineuronal abnormalities. J Biol Chem. 2009 Sep 25; 284(39):26882-96. Lopez IA, Rosenblatt MI, Kim C, Galbraith GC, Jones SM, Kao L, Newman D, Liu W, Yeh S, Pushkin A, Abuladze N, Kurtz I. PMID: 19586905.
      View in: PubMed   Mentions: 34     Fields:    Translation:HumansAnimalsCells
    13. Mouse aminoacylase 3: a metalloenzyme activated by cobalt and nickel. Biochim Biophys Acta. 2009 Jul; 1794(7):1049-57. Tsirulnikov K, Abuladze N, Newman D, Ryazantsev S, Wolak T, Magilnick N, Koag MC, Kurtz I, Pushkin A. PMID: 19362172.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansAnimalsCells
    14. NBCe1-A Transmembrane Segment 1 Lines the Ion Translocation Pathway. J Biol Chem. 2009 Mar 27; 284(13):8918-29. Zhu Q, Azimov R, Kao L, Newman D, Liu W, Abuladze N, Pushkin A, Kurtz I. PMID: 19158093.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansCells
    15. Oligomeric structure and minimal functional unit of the electrogenic sodium bicarbonate cotransporter NBCe1-A. J Biol Chem. 2008 Sep 26; 283(39):26782-94. Kao L, Sassani P, Azimov R, Pushkin A, Abuladze N, Peti-Peterdi J, Liu W, Newman D, Kurtz I. PMID: 18658147.
      View in: PubMed   Mentions: 37     Fields:    Translation:HumansAnimalsCells
    16. G418-mediated ribosomal read-through of a nonsense mutation causing autosomal recessive proximal renal tubular acidosis. Am J Physiol Renal Physiol. 2008 Sep; 295(3):F633-41. Azimov R, Abuladze N, Sassani P, Newman D, Kao L, Liu W, Orozco N, Ruchala P, Pushkin A, Kurtz I. PMID: 18614622.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
    17. Measurement of aminoacylases. Curr Protoc Toxicol. 2008 Feb; Chapter 6:Unit6.14. Pushkin A, Kurtz I. PMID: 23045009.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    18. Structural characterization of dimeric murine aminoacylase III. FEBS Lett. 2007 May 01; 581(9):1898-902. Ryazantsev S, Abuladze N, Newman D, Bondar G, Kurtz I, Pushkin A. PMID: 17434493.
      View in: PubMed   Mentions: 6     Fields:    Translation:AnimalsCells
    19. Specificity of aminoacylase III-mediated deacetylation of mercapturic acids. Drug Metab Dispos. 2007 Jan; 35(1):43-50. Newman D, Abuladze N, Scholz K, Dekant W, Tsuprun V, Ryazantsev S, Bondar G, Sassani P, Kurtz I, Pushkin A. PMID: 17012540.
      View in: PubMed   Mentions: 11     Fields:    Translation:AnimalsCells
    20. SLC4 base (HCO3 -, CO3 2-) transporters: classification, function, structure, genetic diseases, and knockout models. Am J Physiol Renal Physiol. 2006 Mar; 290(3):F580-99. Pushkin A, Kurtz I. PMID: 16461757.
      View in: PubMed   Mentions: 69     Fields:    Translation:HumansAnimalsCells
    21. Critical amino acid residues involved in the electrogenic sodium-bicarbonate cotransporter kNBC1-mediated transport. J Physiol. 2005 Jun 15; 565(Pt 3):717-30. Abuladze N, Azimov R, Newman D, Sassani P, Liu W, Tatishchev S, Pushkin A, Kurtz I. PMID: 15817634.
      View in: PubMed   Mentions: 21     Fields:    Translation:HumansCells
    22. Molecular mechanism of kNBC1-carbonic anhydrase II interaction in proximal tubule cells. J Physiol. 2004 Aug 15; 559(Pt 1):55-65. Pushkin A, Abuladze N, Gross E, Newman D, Tatishchev S, Lee I, Fedotoff O, Bondar G, Azimov R, Ngyuen M, Kurtz I. PMID: 15218065.
      View in: PubMed   Mentions: 36     Fields:    Translation:HumansAnimalsCells
    23. Expression and localization of rat NBC4c in liver and renal uroepithelium. . 2004 Sep; 287(3):C781-9. Abuladze N, Pushkin A, Tatishchev S, Newman D, Sassani P, Kurtz I. PMID: 15151908.
      View in: PubMed   Mentions:
    24. Structural characterization, tissue distribution, and functional expression of murine aminoacylase III. . 2004 Apr; 286(4):C848-56. Pushkin A, Carpenito G, Abuladze N, Newman D, Tsuprun V, Ryazantsev S, Motemoturu S, Sassani P, Solovieva N, Dukkipati R, Kurtz I. PMID: 14656720.
      View in: PubMed   Mentions:
    25. Blindness and auditory impairment caused by loss of the sodium bicarbonate cotransporter NBC3. Nat Genet. 2003 Jul; 34(3):313-9. Bok D, Galbraith G, Lopez I, Woodruff M, Nusinowitz S, BeltrandelRio H, Huang W, Zhao S, Geske R, Montgomery C, Van Sligtenhorst I, Friddle C, Platt K, Sparks MJ, Pushkin A, Abuladze N, Ishiyama A, Dukkipati R, Liu W, Kurtz I. PMID: 12808454.
      View in: PubMed   Mentions: 45     Fields:    Translation:AnimalsCells
    26. Identification of membrane topography of the electrogenic sodium bicarbonate cotransporter pNBC1 by in vitro transcription/translation. Biochemistry. 2003 Jan 28; 42(3):755-65. Tatishchev S, Abuladze N, Pushkin A, Newman D, Liu W, Weeks D, Sachs G, Kurtz I. PMID: 12534288.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansAnimalsCells
    27. The COOH termini of NBC3 and the 56-kDa H+-ATPase subunit are PDZ motifs involved in their interaction. . 2003 Mar; 284(3):C667-73. Pushkin A, Abuladze N, Newman D, Muronets V, Sassani P, Tatishchev S, Kurtz I. PMID: 12444018.
      View in: PubMed   Mentions:
    28. Regulation of the sodium bicarbonate cotransporter kNBC1 function: role of Asp(986), Asp(988) and kNBC1-carbonic anhydrase II binding. J Physiol. 2002 11 01; 544(3):679-85. Gross E, Pushkin A, Abuladze N, Fedotoff O, Kurtz I. PMID: 12411514.
      View in: PubMed   Mentions: 29     Fields:    Translation:AnimalsCells
    29. The cystic fibrosis transmembrane conductance regulator interacts with and regulates the activity of the HCO3- salvage transporter human Na+-HCO3- cotransport isoform 3. J Biol Chem. 2002 Dec 27; 277(52):50503-9. Park M, Ko SB, Choi JY, Muallem G, Thomas PJ, Pushkin A, Lee MS, Kim JY, Lee MG, Muallem S, Kurtz I. PMID: 12403779.
      View in: PubMed   Mentions: 34     Fields:    Translation:HumansCells
    30. Functional characterization of NBC4: a new electrogenic sodium-bicarbonate cotransporter. . 2002 Feb; 282(2):C408-16. Sassani P, Pushkin A, Gross E, Gomer A, Abuladze N, Dukkipati R, Carpenito G, Kurtz I. PMID: 11788353.
      View in: PubMed   Mentions:
    31. Genomic organization of the DCTN1-SLC4A5 locus encoding both NBC4 and p150(Glued). Cytogenet Cell Genet. 2001; 95(3-4):163-8. Pushkin A, Abuladze N, Newman D, Tatishchev S, Kurtz I. PMID: 12063394.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    32. Oligomeric structure of bAE3 protein. IUBMB Life. 2000 Dec; 50(6):397-401. Pushkin AV, Tsuprun VL, Abuladze NK, Newman D, Kurtz I. PMID: 11327314.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    33. Two C-terminal variants of NBC4, a new member of the sodium bicarbonate cotransporter family: cloning, characterization, and localization. IUBMB Life. 2000 Jul; 50(1):13-9. Pushkin A, Abuladze N, Newman D, Lee I, Xu G, Kurtz I. PMID: 11087115.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansCells
    Alexander's Networks
    Concepts (182)
    Derived automatically from this person's publications.
    _
    Co-Authors (7)
    People in Profiles who have published with this person.
    _
    Similar People (60)
    People who share similar concepts with this person.
    _
    Same Department
    Search Department
    _