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Ira Kurtz

Title(s)Professor, Medicine
SchoolMedicine
Phone66741
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    Collapse Research 
    Collapse Research Activities and Funding
    The Biology of NBCe1 in Health and Disease
    NIH/NIDDK R01DK077162Mar 19, 2019 - Nov 30, 2016
    Role: Principal Investigator
    Modulation of Electrogenic Sodium Bicarbonate Transport
    NIH/NIDDK R01DK063125Jan 1, 2003 - Dec 31, 2008
    Role: Principal Investigator
    Biology of Sodium Bicarbonate Transport
    NIH/NIDDK R01DK058563Mar 1, 2001 - Feb 28, 2006
    Role: Principal Investigator
    Nephrology Scientist Training Grant
    NIH/NIDDK T32DK007789Sep 30, 2000 - Jun 30, 2012
    Role: Principal Investigator
    NA+ AND CL- TRANSPORT IN THE MAMMALIAN PROXIMAL TUBULE
    NIH/NIDDK R01DK046976May 20, 1997 - Apr 30, 2001
    Role: Principal Investigator
    CONFOCAL MICROSCOPY--COLLECTING DUCT PHI REGULATION
    NIH/NIDDK R01DK041212Aug 1, 1991 - Jul 31, 1997
    Role: Principal Investigator
    INTRACELLULAR PH REGULATION IN THE KIDNEY TUBULE
    NIH/NIDDK R29DK039212Aug 15, 1987 - Dec 31, 1991
    Role: Principal Investigator
    INTRACELLULAR PH REGULATION IN THE MEDULLARY TUBULE
    NIH/NIDDK R23DK036324Jan 1, 1986 - Jul 31, 1987
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Frausto RF, Swamy VS, Peh GSL, Boere PM, Hanser EM, Chung DD, George BL, Morselli M, Kao L, Azimov R, Wu J, Pellegrini M, Kurtz I, Mehta JS, Aldave AJ. Phenotypic and functional characterization of corneal endothelial cells during in vitro expansion. Sci Rep. 2020 May 04; 10(1):7402. PMID: 32366916.
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    2. Selamet U, Hanna RM, Sisk A, Abdelnour L, Ghobry L, Kurtz I. Acute interstitial nephritis and drug-induced systemic lupus erythematosus due to chlorthalidone and amiodarone: A case report. SAGE Open Med Case Rep. 2020; 8:2050313X20910029. PMID: 32166031.
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    3. Hanna RM, Abdelnour L, Hasnain H, Selamet U, Kurtz I. Intravitreal bevacizumab-induced exacerbation of proteinuria in diabetic nephropathy, and amelioration by switching to ranibizumab. SAGE Open Med Case Rep. 2020; 8:2050313X20907033. PMID: 32110410.
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    4. Nguyen MK, Song L, Kao L, Tong K, De La Cruz MJ, Rodriguez G, Nguyen MK, Nguyen DS, Kurtz I. Is the Osmolal Concentration of Ethanol Greater Than Its Molar Concentration? Front Med (Lausanne). 2019; 6:306. PMID: 31970159.
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    5. Kao L, Azimov R, Shao XM, Abuladze N, Newman D, Zhekova H, Noskov S, Pushkin A, Kurtz I. SLC4A11 function: evidence for H+(OH-) and NH3-H+ transport. Am J Physiol Cell Physiol. 2020 Feb 01; 318(2):C392-C405. PMID: 31774702.
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    6. Frausto RF, Chung DD, Boere PM, Swamy VS, Duong HNV, Kao L, Azimov R, Zhang W, Carrigan L, Wong D, Morselli M, Zakharevich M, Hanser EM, Kassels AC, Kurtz I, Pellegrini M, Aldave AJ. ZEB1 insufficiency causes corneal endothelial cell state transition and altered cellular processing. PLoS One. 2019; 14(6):e0218279. PMID: 31194824.
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    7. Hanna RM, Barsoum M, Vandross A, Kurtz I, Burwick R. Atypical hemolytic uremic syndrome and complement blockade: established and emerging uses of complement inhibition. Curr Opin Nephrol Hypertens. 2019 05; 28(3):278-287. PMID: 30865166.
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    8. Hanna RM, Barsoum M, Arman F, Selamet U, Hasnain H, Kurtz I. Nephrotoxicity induced by intravitreal vascular endothelial growth factor inhibitors: emerging evidence. Kidney Int. 2019 Sep; 96(3):572-580. PMID: 31229276.
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    9. Lang JM, Pan C, Cantor RM, Tang WHW, Garcia-Garcia JC, Kurtz I, Hazen SL, Bergeron N, Krauss RM, Lusis AJ. Impact of Individual Traits, Saturated Fat, and Protein Source on the Gut Microbiome. mBio. 2018 12 11; 9(6). PMID: 30538180.
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    10. Song L, Hanna RM, Nguyen MK, Kurtz I, Wilson J. A Novel Case of Pseudohyponatremia Caused by Hypercholesterolemia. Kidney Int Rep. 2019 Mar; 4(3):491-493. PMID: 30899877.
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    11. Kurtz I. Renal Tubular Acidosis: H+/Base and Ammonia Transport Abnormalities and Clinical Syndromes. Adv Chronic Kidney Dis. 2018 07; 25(4):334-350. PMID: 30139460.
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    12. Huynh KW, Jiang J, Abuladze N, Tsirulnikov K, Kao L, Shao X, Newman D, Azimov R, Pushkin A, Zhou ZH, Kurtz I. CryoEM structure of the human SLC4A4 sodium-coupled acid-base transporter NBCe1. Nat Commun. 2018 03 02; 9(1):900. PMID: 29500354.
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    13. Tsirulnikov K, Duarte S, Ray A, Datta N, Zarrinpar A, Hwang L, Faull K, Pushkin A, Kurtz I. Aminoacylase 3 Is a New Potential Marker and Therapeutic Target in Hepatocellular Carcinoma. J Cancer. 2018; 9(1):1-12. PMID: 29290764.
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    14. Zhu Q, Kao L, Azimov R, Abuladze N, Newman D, Kurtz I. Interplay between disulfide bonding and N-glycosylation defines SLC4 Na+-coupled transporter extracellular topography. J Biol Chem. 2015 Feb 27; 290(9):5391-404. PMID: 25568315.
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    15. Shcheynikov N, Son A, Hong JH, Yamazaki O, Ohana E, Kurtz I, Shin DM, Muallem S. Intracellular Cl- as a signaling ion that potently regulates Na+/HCO3- transporters. Proc Natl Acad Sci U S A. 2015 Jan 20; 112(3):E329-37. PMID: 25561556.
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    16. Shao XM, Kao L, Kurtz I. A novel delta current method for transport stoichiometry estimation. BMC Biophys. 2014; 7(1):14. PMID: 25558372.
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    17. Kraut JA, Kurtz I. Treatment of acute non-anion gap metabolic acidosis. Clin Kidney J. 2015 Feb; 8(1):93-9. PMID: 25852932.
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    18. Kao L, Azimov R, Abuladze N, Newman D, Kurtz I. Human SLC4A11-C functions as a DIDS-stimulatable H?(OH?) permeation pathway: partial correction of R109H mutant transport. Am J Physiol Cell Physiol. 2015 Jan 15; 308(2):C176-88. PMID: 25394471.
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    19. Kurtz I. Molecular mechanisms and regulation of urinary acidification. Compr Physiol. 2014 Oct; 4(4):1737-74. PMID: 25428859.
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    20. Nguyen MK, Ornekian V, Kao L, Butch AW, Kurtz I. Defining the role of albumin infusion in cirrhosis-associated hyponatremia. Am J Physiol Gastrointest Liver Physiol. 2014 Jul 15; 307(2):G229-32. PMID: 24833711.
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    21. Kurtz I. NBCe1 as a model carrier for understanding the structure-function properties of Na? -coupled SLC4 transporters in health and disease. Pflugers Arch. 2014 Aug; 466(8):1501-16. PMID: 24515290.
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    22. Kurtz I, Zhu Q. Proximal renal tubular acidosis mediated by mutations in NBCe1-A: unraveling the transporter's structure-functional properties. Front Physiol. 2013 Dec 19; 4:350. PMID: 24391589.
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    23. Kurtz I, Zhu Q. Structure, function, and regulation of the SLC4 NBCe1 transporter and its role in causing proximal renal tubular acidosis. Curr Opin Nephrol Hypertens. 2013 Sep; 22(5):572-83. PMID: 23917030.
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    24. Zhu Q, Shao XM, Kao L, Azimov R, Weinstein AM, Newman D, Liu W, Kurtz I. Missense mutation T485S alters NBCe1-A electrogenicity causing proximal renal tubular acidosis. Am J Physiol Cell Physiol. 2013 Aug 15; 305(4):C392-405. PMID: 23636456.
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    25. Zhu Q, Liu W, Kao L, Azimov R, Newman D, Abuladze N, Kurtz I. Topology of NBCe1 protein transmembrane segment 1 and structural effect of proximal renal tubular acidosis (pRTA) S427L mutation. J Biol Chem. 2013 Mar 15; 288(11):7894-906. PMID: 23362273.
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    26. Tsirulnikov K, Abuladze N, Vahi R, Hasnain H, Phillips M, Ryan CM, Atanasov I, Faull KF, Kurtz I, Pushkin A. Aminoacylase 3 binds to and cleaves the N-terminus of the hepatitis C virus core protein. FEBS Lett. 2012 Nov 02; 586(21):3799-804. PMID: 23010594.
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    27. Kurtz L, Kao L, Newman D, Kurtz I, Zhu Q. Integrin aIIbß3 inside-out activation: an in situ conformational analysis reveals a new mechanism. J Biol Chem. 2012 Jun 29; 287(27):23255-65. PMID: 22613710.
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    28. Kao L, Abuladze N, Shao XM, McKeegan K, Kurtz I. A new technique for multiple re-use of planar patch clamp chips. J Neurosci Methods. 2012 Jul 15; 208(2):205-10. PMID: 22609774.
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    29. Sergeev M, Godin AG, Kao L, Abuladze N, Wiseman PW, Kurtz I. Determination of membrane protein transporter oligomerization in native tissue using spatial fluorescence intensity fluctuation analysis. PLoS One. 2012; 7(4):e36215. PMID: 22558387.
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    30. Lacruz RS, Smith CE, Moffatt P, Chang EH, Bromage TG, Bringas P, Nanci A, Baniwal SK, Zabner J, Welsh MJ, Kurtz I, Paine ML. Requirements for ion and solute transport, and pH regulation during enamel maturation. J Cell Physiol. 2012 Apr; 227(4):1776-85. PMID: 21732355.
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    31. Nguyen MK, Kao L, Kurtz I. Defining the buffering process by a triprotic acid without relying on Stewart-electroneutrality considerations. Theor Biol Med Model. 2011 Aug 17; 8:29. PMID: 21849064.
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    32. Kao L, Kurtz LM, Shao X, Papadopoulos MC, Liu L, Bok D, Nusinowitz S, Chen B, Stella SL, Andre M, Weinreb J, Luong SS, Piri N, Kwong JM, Newman D, Kurtz I. Severe neurologic impairment in mice with targeted disruption of the electrogenic sodium bicarbonate cotransporter NBCe2 (Slc4a5 gene). J Biol Chem. 2011 Sep 16; 286(37):32563-74. PMID: 21705333.
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    33. Hsieh JM, Tsirulnikov K, Sawaya MR, Magilnick N, Abuladze N, Kurtz I, Abramson J, Pushkin A. Structures of aminoacylase 3 in complex with acetylated substrates. Proc Natl Acad Sci U S A. 2010 Oct 19; 107(42):17962-7. PMID: 20921362.
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    34. Zhu Q, Kao L, Azimov R, Abuladze N, Newman D, Pushkin A, Liu W, Chang C, Kurtz I. Structural and functional characterization of the C-terminal transmembrane region of NBCe1-A. J Biol Chem. 2010 Nov 26; 285(48):37178-87. PMID: 20837482.
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    35. Lacruz RS, Nanci A, White SN, Wen X, Wang H, Zalzal SF, Luong VQ, Schuetter VL, Conti PS, Kurtz I, Paine ML. The sodium bicarbonate cotransporter (NBCe1) is essential for normal development of mouse dentition. J Biol Chem. 2010 Aug 06; 285(32):24432-8. PMID: 20529845.
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    36. Zhu Q, Kao L, Azimov R, Newman D, Liu W, Pushkin A, Abuladze N, Kurtz I. Topological location and structural importance of the NBCe1-A residues mutated in proximal renal tubular acidosis. J Biol Chem. 2010 Apr 30; 285(18):13416-26. PMID: 20197274.
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    37. Lacruz RS, Hilvo M, Kurtz I, Paine ML. A survey of carbonic anhydrase mRNA expression in enamel cells. Biochem Biophys Res Commun. 2010 Mar 19; 393(4):883-7. PMID: 20175995.
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    38. Tsirulnikov K, Abuladze N, Koag MC, Newman D, Scholz K, Bondar G, Zhu Q, Avliyakulov NK, Dekant W, Faull K, Kurtz I, Pushkin A. Transport of N-acetyl-S-(1,2-dichlorovinyl)-L-cysteine, a metabolite of trichloroethylene, by mouse multidrug resistance associated protein 2 (Mrp2). Toxicol Appl Pharmacol. 2010 Apr 15; 244(2):218-25. PMID: 20060011.
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    39. Lopez IA, Rosenblatt MI, Kim C, Galbraith GC, Jones SM, Kao L, Newman D, Liu W, Yeh S, Pushkin A, Abuladze N, Kurtz I. Slc4a11 gene disruption in mice: cellular targets of sensorineuronal abnormalities. J Biol Chem. 2009 Sep 25; 284(39):26882-96. PMID: 19586905.
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    40. Tsirulnikov K, Abuladze N, Newman D, Ryazantsev S, Wolak T, Magilnick N, Koag MC, Kurtz I, Pushkin A. Mouse aminoacylase 3: a metalloenzyme activated by cobalt and nickel. Biochim Biophys Acta. 2009 Jul; 1794(7):1049-57. PMID: 19362172.
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    41. Nguyen MK, Kao L, Kurtz I. Calculation of the equilibrium pH in a multiple-buffered aqueous solution based on partitioning of proton buffering: a new predictive formula. Am J Physiol Renal Physiol. 2009 Jun; 296(6):F1521-9. PMID: 19339630.
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    42. Zhu Q, Azimov R, Kao L, Newman D, Liu W, Abuladze N, Pushkin A, Kurtz I. NBCe1-A Transmembrane Segment 1 Lines the Ion Translocation Pathway. J Biol Chem. 2009 Mar 27; 284(13):8918-29. PMID: 19158093.
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    43. Kao L, Sassani P, Azimov R, Pushkin A, Abuladze N, Peti-Peterdi J, Liu W, Newman D, Kurtz I. Oligomeric structure and minimal functional unit of the electrogenic sodium bicarbonate cotransporter NBCe1-A. J Biol Chem. 2008 Sep 26; 283(39):26782-94. PMID: 18658147.
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    44. Azimov R, Abuladze N, Sassani P, Newman D, Kao L, Liu W, Orozco N, Ruchala P, Pushkin A, Kurtz I. G418-mediated ribosomal read-through of a nonsense mutation causing autosomal recessive proximal renal tubular acidosis. Am J Physiol Renal Physiol. 2008 Sep; 295(3):F633-41. PMID: 18614622.
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    45. Nguyen MK, Kurtz I. Correction of hypervolaemic hypernatraemia by inducing negative Na+ and K+ balance in excess of negative water balance: a new quantitative approach. Nephrol Dial Transplant. 2008 Jul; 23(7):2223-7. PMID: 18283087.
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    46. Pushkin A, Kurtz I. Measurement of aminoacylases. Curr Protoc Toxicol. 2008 Feb; Chapter 6:Unit6.14. PMID: 23045009.
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    47. Kurtz I, Kraut J, Ornekian V, Nguyen MK. Acid-base analysis: a critique of the Stewart and bicarbonate-centered approaches. Am J Physiol Renal Physiol. 2008 May; 294(5):F1009-31. PMID: 18184741.
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    48. Kraut JA, Kurtz I. Toxic alcohol ingestions: clinical features, diagnosis, and management. Clin J Am Soc Nephrol. 2008 Jan; 3(1):208-25. PMID: 18045860.
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    49. Aldave AJ, Yellore VS, Bourla N, Momi RS, Khan MA, Salem AK, Rayner SA, Glasgow BJ, Kurtz I. Autosomal recessive CHED associated with novel compound heterozygous mutations in SLC4A11. Cornea. 2007 Aug; 26(7):896-900. PMID: 17667634.
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    50. Nguyen MK, Ornekian V, Butch AW, Kurtz I. A new method for determining plasma water content: application in pseudohyponatremia. Am J Physiol Renal Physiol. 2007 May; 292(5):F1652-6. PMID: 17299138.
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    51. Suh WM, Wainberg ZA, de Vos S, Cohen AH, Kurtz I, Nguyen MK. Acute lymphoblastic leukemia presenting as acute renal failure. Nat Clin Pract Nephrol. 2007 Feb; 3(2):106-10. PMID: 17251998.
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    52. Nguyen MK, Kurtz I. Is the osmotically inactive sodium storage pool fixed or variable? J Appl Physiol (1985). 2007 Jan; 102(1):445-7. PMID: 16916917.
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    53. Nguyen MK, Rastogi A, Kurtz I. True hyponatremia secondary to intravenous immunoglobulin. Clin Exp Nephrol. 2006 Jun; 10(2):124-6. PMID: 16791398.
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    54. Kraut JA, Kurtz I. Use of base in the treatment of acute severe organic acidosis by nephrologists and critical care physicians: results of an online survey. Clin Exp Nephrol. 2006 Jun; 10(2):111-7. PMID: 16791396.
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    55. Nguyen MK, Kurtz I. Physiologic Interrelationships between Gibbs-Donnan Equilibrium, Osmolality of Body Fluid Compartments, and Plasma Water Sodium Concentration. J Appl Physiol (1985). 2006 May 11. PMID: 16690786.
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    56. Kalantar-Zadeh K, Nguyen MK, Chang R, Kurtz I. Fatal hyponatremia in a young woman after ecstasy ingestion. Nat Clin Pract Nephrol. 2006 May; 2(5):283-8, quiz 289. PMID: 16932441.
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    57. Pushkin A, Kurtz I. SLC4 base (HCO3 -, CO3 2-) transporters: classification, function, structure, genetic diseases, and knockout models. Am J Physiol Renal Physiol. 2006 Mar; 290(3):F580-99. PMID: 16461757.
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    58. Nguyen MK, Kurtz I. Whole-body electrolyte-free water clearance: derivation and clinical utility in analyzing the pathogenesis of the dysnatremias. Clin Exp Nephrol. 2006 Mar; 10(1):19-24. PMID: 16544174.
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    59. Galbraith G, Waschek J, Armstrong B, Edmond J, Lopez I, Liu W, Kurtz I. Murine auditory brainstem evoked response: putative two-channel differentiation of peripheral and central neural pathways. J Neurosci Methods. 2006 Jun 15; 153(2):214-20. PMID: 16406043.
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    60. Nguyen MK, Kurtz I. Quantitative interrelationship between Gibbs-Donnan equilibrium, osmolality of body fluid compartments, and plasma water sodium concentration. J Appl Physiol (1985). 2006 Apr; 100(4):1293-300. PMID: 16357067.
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    61. Kurtz I, Nguyen MK. Evolving concepts in the quantitative analysis of the determinants of the plasma water sodium concentration and the pathophysiology and treatment of the dysnatremias. Kidney Int. 2005 Nov; 68(5):1982-93. PMID: 16221198.
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    62. Lopez IA, Acuna D, Galbraith G, Bok D, Ishiyama A, Liu W, Kurtz I. Time course of auditory impairment in mice lacking the electroneutral sodium bicarbonate cotransporter NBC3 (slc4a7). Brain Res Dev Brain Res. 2005 Nov 07; 160(1):63-77. PMID: 16181686.
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    63. Kraut JA, Kurtz I. Metabolic acidosis of CKD: diagnosis, clinical characteristics, and treatment. Am J Kidney Dis. 2005 Jun; 45(6):978-93. PMID: 15957126.
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    64. Abuladze N, Azimov R, Newman D, Sassani P, Liu W, Tatishchev S, Pushkin A, Kurtz I. Critical amino acid residues involved in the electrogenic sodium-bicarbonate cotransporter kNBC1-mediated transport. J Physiol. 2005 Jun 15; 565(Pt 3):717-30. PMID: 15817634.
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    65. Nguyen MK, Kurtz I. An analysis of current quantitative approaches to the treatment of severe symptomatic SIADH with intravenous saline therapy. Clin Exp Nephrol. 2005 Mar; 9(1):1-4. PMID: 15830266.
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    66. Nguyen MK, Kurtz I. A new formula for predicting alterations in plasma sodium concentration in peritoneal dialysis. Am J Physiol Renal Physiol. 2005 Jun; 288(6):F1113-7. PMID: 15625082.
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    67. Nguyen MK, Kurtz I. Derivation of a new formula for calculating urinary electrolyte-free water clearance based on the Edelman equation. Am J Physiol Renal Physiol. 2005 Jan; 288(1):F1-7. PMID: 15383402.
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    68. Nguyen MK, Kurtz I. New insights into the pathophysiology of the dysnatremias: a quantitative analysis. Am J Physiol Renal Physiol. 2004 Aug; 287(2):F172-80. PMID: 15271684.
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    69. Pushkin A, Abuladze N, Gross E, Newman D, Tatishchev S, Lee I, Fedotoff O, Bondar G, Azimov R, Ngyuen M, Kurtz I. Molecular mechanism of kNBC1-carbonic anhydrase II interaction in proximal tubule cells. J Physiol. 2004 Aug 15; 559(Pt 1):55-65. PMID: 15218065.
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    70. Nguyen MK, Kurtz I. Role of potassium in hypokalemia-induced hyponatremia: lessons learned from the Edelman equation. Clin Exp Nephrol. 2004 Jun; 8(2):98-102. PMID: 15235925.
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    71. Abuladze N, Pushkin A, Tatishchev S, Newman D, Sassani P, Kurtz I. Expression and localization of rat NBC4c in liver and renal uroepithelium. Am J Physiol Cell Physiol. 2004 Sep; 287(3):C781-9. PMID: 15151908.
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    72. Nguyen MK, Kurtz I. Analysis of current formulas used for treatment of the dysnatremias. Clin Exp Nephrol. 2004 Mar; 8(1):12-6. PMID: 15067511.
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    73. Nguyen MK, Kurtz I. Determinants of plasma water sodium concentration as reflected in the Edelman equation: role of osmotic and Gibbs-Donnan equilibrium. Am J Physiol Renal Physiol. 2004 May; 286(5):F828-37. PMID: 15075178.
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    74. Kurtz I, Petrasek D, Tatishchev S. Molecular mechanisms of electrogenic sodium bicarbonate cotransport: structural and equilibrium thermodynamic considerations. J Membr Biol. 2004 Jan 15; 197(2):77-90. PMID: 15014910.
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    75. Pushkin A, Carpenito G, Abuladze N, Newman D, Tsuprun V, Ryazantsev S, Motemoturu S, Sassani P, Solovieva N, Dukkipati R, Kurtz I. Structural characterization, tissue distribution, and functional expression of murine aminoacylase III. Am J Physiol Cell Physiol. 2004 Apr; 286(4):C848-56. PMID: 14656720.
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    76. Woo DD, Kurtz I. Mapping blood pressure loci in (A/J x B6)F2 mice. Physiol Genomics. 2003 Nov 11; 15(3):236-42. PMID: 14612590.
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    77. Nguyen MK, Kurtz I. An unusual case of pseudohyperkalaemia. Nephrol Dial Transplant. 2003 Aug; 18(8):1657-9. PMID: 12897110.
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    78. Nguyen MK, Kurtz I. Are the total exchangeable sodium, total exchangeable potassium and total body water the only determinants of the plasma water sodium concentration? Nephrol Dial Transplant. 2003 Jul; 18(7):1266-71. PMID: 12808160.
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    79. Bok D, Galbraith G, Lopez I, Woodruff M, Nusinowitz S, BeltrandelRio H, Huang W, Zhao S, Geske R, Montgomery C, Van Sligtenhorst I, Friddle C, Platt K, Sparks MJ, Pushkin A, Abuladze N, Ishiyama A, Dukkipati R, Liu W, Kurtz I. Blindness and auditory impairment caused by loss of the sodium bicarbonate cotransporter NBC3. Nat Genet. 2003 Jul; 34(3):313-9. PMID: 12808454.
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    80. Kurtz I, Nguyen MK. A simple quantitative approach to analyzing the generation of the dysnatremias. Clin Exp Nephrol. 2003 Jun; 7(2):138-43. PMID: 14586732.
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    81. Nguyen MK, Kurtz I. A new quantitative approach to the treatment of the dysnatremias. Clin Exp Nephrol. 2003 Jun; 7(2):125-37. PMID: 14586731.
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    82. Nguyen MK, Nielsen S, Kurtz I. Molecular pathogenesis of nephrogenic diabetes insipidus. Clin Exp Nephrol. 2003 Mar; 7(1):9-17. PMID: 14586738.
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    83. Tatishchev S, Abuladze N, Pushkin A, Newman D, Liu W, Weeks D, Sachs G, Kurtz I. Identification of membrane topography of the electrogenic sodium bicarbonate cotransporter pNBC1 by in vitro transcription/translation. Biochemistry. 2003 Jan 28; 42(3):755-65. PMID: 12534288.
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    84. Pushkin A, Abuladze N, Newman D, Muronets V, Sassani P, Tatishchev S, Kurtz I. The COOH termini of NBC3 and the 56-kDa H+-ATPase subunit are PDZ motifs involved in their interaction. Am J Physiol Cell Physiol. 2003 Mar; 284(3):C667-73. PMID: 12444018.
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    85. Yip KP, Tsuruoka S, Schwartz GJ, Kurtz I. Apical H(+)/base transporters mediating bicarbonate absorption and pH(i) regulation in the OMCD. Am J Physiol Renal Physiol. 2002 Nov; 283(5):F1098-104. PMID: 12372786.
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    86. Gross E, Kurtz I. Structural determinants and significance of regulation of electrogenic Na(+)-HCO(3)(-) cotransporter stoichiometry. Am J Physiol Renal Physiol. 2002 Nov; 283(5):F876-87. PMID: 12372762.
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    87. Carpenito G, Kurtz I. Green urine in a critically ill patient. Am J Kidney Dis. 2002 Apr; 39(4):E20. PMID: 11920362.
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    88. Kwon TH, Fulton C, Wang W, Kurtz I, Frøkiaer J, Aalkjaer C, Nielsen S. Chronic metabolic acidosis upregulates rat kidney Na-HCO cotransporters NBCn1 and NBC3 but not NBC1. Am J Physiol Renal Physiol. 2002 Feb; 282(2):F341-51. PMID: 11788449.
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    89. Sassani P, Pushkin A, Gross E, Gomer A, Abuladze N, Dukkipati R, Carpenito G, Kurtz I. Functional characterization of NBC4: a new electrogenic sodium-bicarbonate cotransporter. Am J Physiol Cell Physiol. 2002 Feb; 282(2):C408-16. PMID: 11788353.
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