Jeffrey Kraut

Title(s)Professor-in-Residence, Medicine
Address555 Westwood Plaza MAILROOM
Los Angeles CA 90024
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    1. Drug removal of gastric acid: a novel treatment of metabolic acidosis. Lancet. 2019 08 03; 394(10196):363-364. Kraut JA, Raphael KL. PMID: 31248664.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    2. Treatment of acute acidaemia in the seriously ill patient: Should base be given? Anaesth Crit Care Pain Med. 2018 12; 37(6):495-497. Kraut JA. PMID: 30573203.
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    3. Intravenous Sodium Bicarbonate in Treating Patients With Severe Metabolic Acidemia. Am J Kidney Dis. 2019 04; 73(4):572-575. Kraut JA, Madias NE. PMID: 30343957.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    4. Re-Evaluation of Total CO2 Concentration in Apparently Healthy Younger Adults. Am J Nephrol. 2018; 48(1):15-20. Kraut JA, Lew V, Madias NE. PMID: 29990967.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    5. Sodium bicarbonate for severe metabolic acidaemia. Lancet. 2018 07 07; 392(10141):3-4. Kraut JA, Madias NE. PMID: 29910039.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    6. Retarding progression of chronic kidney disease: use of modalities that counter acid retention. Curr Opin Nephrol Hypertens. 2018 03; 27(2):94-101. Kraut JA, Madias NE. PMID: 29140821.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimals
    7. Toxic Alcohols. N Engl J Med. 2018 01 18; 378(3):270-280. Kraut JA, Mullins ME. PMID: 29342392.
      View in: PubMed   Mentions: 10     Fields:    Translation:Humans
    8. Re-Evaluation of the Normal Range of Serum Total CO2 Concentration. Clin J Am Soc Nephrol. 2018 02 07; 13(2):343-347. Kraut JA, Madias NE. PMID: 29339355.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    9. Adverse Effects of the Metabolic Acidosis of Chronic Kidney Disease. Adv Chronic Kidney Dis. 2017 09; 24(5):289-297. Kraut JA, Madias NE. PMID: 29031355.
      View in: PubMed   Mentions: 10     Fields:    Translation:Humans
    10. Disturbances in Acid-Base, Potassium, and Sodium Balance in Patients With CKD: New Insights and Novel Therapies. Adv Chronic Kidney Dis. 2017 09; 24(5):272-273. Kraut JA. PMID: 29031352.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    11. Treatment of Acidified Blood Using Reduced Osmolarity Mixed-Base Solutions. Front Physiol. 2016; 7:625. Mason TG, Kraut JA. PMID: 28082905.
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    12. Adverse postresuscitation myocardial effects elicited by buffer-induced alkalemia ameliorated by NHE-1 inhibition in a rat model of ventricular fibrillation. J Appl Physiol (1985). 2016 11 01; 121(5):1160-1168. Lamoureux L, Radhakrishnan J, Mason TG, Kraut JA, Gazmuri RJ. PMID: 27633736.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    13. Lactic Acidosis: Current Treatments and Future Directions. Am J Kidney Dis. 2016 Sep; 68(3):473-82. Kraut JA, Madias NE. PMID: 27291485.
      View in: PubMed   Mentions: 11     Fields:    Translation:Humans
    14. Approach to the Treatment of Methanol Intoxication. Am J Kidney Dis. 2016 Jul; 68(1):161-7. Kraut JA. PMID: 27180631.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    15. Metabolic Acidosis of CKD: An Update. Am J Kidney Dis. 2016 Feb; 67(2):307-17. Kraut JA, Madias NE. PMID: 26477665.
      View in: PubMed   Mentions: 33     Fields:    Translation:HumansAnimals
    16. Diagnosis of toxic alcohols: limitations of present methods. Clin Toxicol (Phila). 2015; 53(7):589-95. Kraut JA. PMID: 26114345.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    17. Interaction of sodium bicarbonate and Na+/H+ exchanger inhibition in the treatment of acute metabolic acidosis in pigs. Crit Care Med. 2015 Jun; 43(6):e160-9. Lin X, More AS, Kraut JA, Wu D. PMID: 25785519.
      View in: PubMed   Mentions: 1     Fields:    Translation:Animals
    18. Lactic acidosis. N Engl J Med. 2015 03 12; 372(11):1078-9. Kraut JA, Madias NE. PMID: 25760366.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    19. Lactic acidosis. N Engl J Med. 2014 Dec 11; 371(24):2309-19. Kraut JA, Madias NE. PMID: 25494270.
      View in: PubMed   Mentions: 99     Fields:    Translation:Humans
    20. Treatment of acute non-anion gap metabolic acidosis. Clin Kidney J. 2015 Feb; 8(1):93-9. Kraut JA, Kurtz I. PMID: 25852932.
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    21. The use and interpretation of serum bicarbonate concentration in dialysis patients. Semin Dial. 2014 Nov-Dec; 27(6):577-9. Kraut JA, Nagami GT. PMID: 24995487.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    22. Role of NHE1 in the cellular dysfunction of acute metabolic acidosis. Am J Nephrol. 2014; 40(1):36-42. Wu D, Kraut JA. PMID: 24994076.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimals
    23. Coadministration of a Na+-H+ exchange inhibitor and sodium bicarbonate for the treatment of asphyxia-induced cardiac arrest in piglets. Pediatr Res. 2014 Aug; 76(2):118-26. Lin X, Kraut JA, Wu D. PMID: 24796369.
      View in: PubMed   Mentions: 4     Fields:    Translation:AnimalsCells
    24. Commentary. Clin Chem. 2014 Mar; 60(3):449. Kraut JA. PMID: 24584408.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    25. Association of serum bicarbonate with clinical outcomes in CKD: could an increase in serum bicarbonate be a double-edged sword? Am J Kidney Dis. 2013 Oct; 62(4):647-9. Kraut JA, Madias NE. PMID: 24054938.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    26. The serum anion gap in the evaluation of acid-base disorders: what are its limitations and can its effectiveness be improved? Clin J Am Soc Nephrol. 2013 Nov; 8(11):2018-24. Kraut JA, Nagami GT. PMID: 23833313.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansAnimals
    27. Sabiporide improves cardiovascular function, decreases the inflammatory response and reduces mortality in acute metabolic acidosis in pigs. PLoS One. 2013; 8(1):e53932. Wu D, Kraut JA, Abraham WM. PMID: 23326542.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimals
    28. Acid stress increases gene expression of proinflammatory cytokines in Madin-Darby canine kidney cells. Am J Physiol Renal Physiol. 2013 Jan 01; 304(1):F41-8. Raj S, Scott DR, Nguyen T, Sachs G, Kraut JA. PMID: 23077097.
      View in: PubMed   Mentions: 5     Fields:    Translation:AnimalsCells
    29. Treatment of acute metabolic acidosis: a pathophysiologic approach. Nat Rev Nephrol. 2012 Oct; 8(10):589-601. Kraut JA, Madias NE. PMID: 22945490.
      View in: PubMed   Mentions: 28     Fields:    Translation:Humans
    30. Differential diagnosis of nongap metabolic acidosis: value of a systematic approach. Clin J Am Soc Nephrol. 2012 Apr; 7(4):671-9. Kraut JA, Madias NE. PMID: 22403272.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansAnimals
    31. Re: Ketoacidosis with unexpected serum isopropyl alcohol. Clin Chem. 2011 Oct; 57(10):1364-5. Kraut JA. PMID: 21956920.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    32. Approach to the evaluation of a patient with an increased serum osmolal gap and high-anion-gap metabolic acidosis. Am J Kidney Dis. 2011 Sep; 58(3):480-4. Kraut JA, Xing SX. PMID: 21794966.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    33. Potential role of NHE1 (sodium-hydrogen exchanger 1) in the cellular dysfunction of lactic acidosis: implications for treatment. Am J Kidney Dis. 2011 May; 57(5):781-7. Wu D, Kraut JA. PMID: 21349616.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimalsCells
    34. Effect of metabolic acidosis on progression of chronic kidney disease. Am J Physiol Renal Physiol. 2011 Apr; 300(4):F828-9. Kraut JA. PMID: 21307127.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    35. Consequences and therapy of the metabolic acidosis of chronic kidney disease. Pediatr Nephrol. 2011 Jan; 26(1):19-28. Kraut JA, Madias NE. PMID: 20526632.
      View in: PubMed   Mentions: 32     Fields:    Translation:HumansAnimals
    36. Metabolic acidosis: pathophysiology, diagnosis and management. Nat Rev Nephrol. 2010 May; 6(5):274-85. Kraut JA, Madias NE. PMID: 20308999.
      View in: PubMed   Mentions: 67     Fields:    Translation:Humans
    37. Acid-base regulation of angiotensin receptors in the kidney. Curr Opin Nephrol Hypertens. 2010 Jan; 19(1):91-7. Nagami GT, Kraut JA. PMID: 19816174.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    38. Role of N-glycosylation in trafficking of apical membrane proteins in epithelia. Am J Physiol Renal Physiol. 2009 Mar; 296(3):F459-69. Vagin O, Kraut JA, Sachs G. PMID: 18971212.
      View in: PubMed   Mentions: 68     Fields:    Translation:Cells
    39. Simple diagnostic tests to detect toxic alcohol intoxications. Transl Res. 2008 Oct; 152(4):194-201. Shin JM, Sachs G, Kraut JA. PMID: 18940722.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    40. Spurious elevation in serum creatinine caused by ingestion of nitromethane: implication for the diagnosis and treatment of methanol intoxication. Am J Kidney Dis. 2008 Jul; 52(1):181-7. Rastogi A, Itagaki B, Bajwa M, Kraut JA. PMID: 18589218.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    41. Acid-base analysis: a critique of the Stewart and bicarbonate-centered approaches. Am J Physiol Renal Physiol. 2008 May; 294(5):F1009-31. Kurtz I, Kraut J, Ornekian V, Nguyen MK. PMID: 18184741.
      View in: PubMed   Mentions: 21     Fields:    Translation:HumansAnimals
    42. Toxic alcohol ingestions: clinical features, diagnosis, and management. Clin J Am Soc Nephrol. 2008 Jan; 3(1):208-25. Kraut JA, Kurtz I. PMID: 18045860.
      View in: PubMed   Mentions: 54     Fields:    Translation:Humans
    43. Urea transport in bacteria: acid acclimation by gastric Helicobacter spp. J Membr Biol. 2006; 212(2):71-82. Sachs G, Kraut JA, Wen Y, Feng J, Scott DR. PMID: 17264989.
      View in: PubMed   Mentions: 23     Fields:    Translation:Cells
    44. Serum anion gap: its uses and limitations in clinical medicine. Clin J Am Soc Nephrol. 2007 Jan; 2(1):162-74. Kraut JA, Madias NE. PMID: 17699401.
      View in: PubMed   Mentions: 58     Fields:    Translation:Humans
    45. Use of base in the treatment of acute severe organic acidosis by nephrologists and critical care physicians: results of an online survey. Clin Exp Nephrol. 2006 Jun; 10(2):111-7. Kraut JA, Kurtz I. PMID: 16791396.
      View in: PubMed   Mentions: 14     Fields:    Translation:Humans
    46. Metabolic acidosis of CKD: diagnosis, clinical characteristics, and treatment. Am J Kidney Dis. 2005 Jun; 45(6):978-93. Kraut JA, Kurtz I. PMID: 15957126.
      View in: PubMed   Mentions: 62     Fields:    Translation:Humans
    47. Hartnup disorder: unraveling the mystery. Trends Pharmacol Sci. 2005 Feb; 26(2):53-5. Kraut JA, Sachs G. PMID: 15681018.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    48. What unique acid-base considerations exist in dialysis patients? Semin Dial. 2004 Sep-Oct; 17(5):351-64. Oh MS, Uribarri J, Weinstein J, Schreiber M, Kamel KS, Kraut JA, Madias NE, Laski ME. PMID: 15461741.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimals
    49. Isometric exercise increases the size of forearm veins in patients with chronic renal failure. Am J Med Sci. 2003 Mar; 325(3):115-9. Leaf DA, MacRae HS, Grant E, Kraut J. PMID: 12640286.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCTClinical Trials
    50. Use of base in the treatment of severe acidemic states. Am J Kidney Dis. 2001 Oct; 38(4):703-27. Kraut JA, Kurtz I. PMID: 11576874.
      View in: PubMed   Mentions: 28     Fields:    Translation:HumansAnimals
    51. Detection and localization of H+-K+-ATPase isoforms in human kidney. Am J Physiol Renal Physiol. 2001 Oct; 281(4):F763-8. Kraut JA, Helander KG, Helander HF, Iroezi ND, Marcus EA, Sachs G. PMID: 11553523.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimals
    52. HEMO equilibrated Kt/V goals are difficult to achieve in large male patients. ASAIO J. 2001 May-Jun; 47(3):235-9. Elangovan L, Shinaberger CS, Kraut JA, Shinaberger JH. PMID: 11374764.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    53. Approach to patients with acid-base disorders. Respir Care. 2001 Apr; 46(4):392-403. Kraut JA, Madias NE. PMID: 11262558.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    54. Disturbances of acid-base balance and bone disease in end-stage renal disease. Semin Dial. 2000 Jul-Aug; 13(4):261-6. Kraut JA. PMID: 10923356.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    55. The Na(+)-K(+)-ATPase beta 1 subunit is associated with the HK alpha 2 protein in the rat kidney. Kidney Int. 1998 Apr; 53(4):958-62. Kraut JA, Hiura J, Shin JM, Smolka A, Sachs G, Scott D. PMID: 9551404.
      View in: PubMed   Mentions: 6     Fields:    Translation:AnimalsCells
    56. Effect of hypokalemia on the abundance of HK alpha 1 and HK alpha 2 protein in the rat kidney. Am J Physiol. 1997 Jun; 272(6 Pt 2):F744-50. Kraut JA, Hiura J, Besancon M, Smolka A, Sachs G, Scott D. PMID: 9227635.
      View in: PubMed   Mentions: 4     Fields:    Translation:Animals
    57. Identifying the physiological electron transfer site of cytochrome c peroxidase by structure-based engineering. Biochemistry. 1996 Jan 23; 35(3):667-73. Miller MA, Geren L, Han GW, Saunders A, Beasley J, Pielak GJ, Durham B, Millett F, Kraut J. PMID: 8547245.
      View in: PubMed   Mentions: 7     Fields:    Translation:AnimalsCells
    58. Effect of chronic respiratory acidosis on calcium metabolism in the rat. J Lab Clin Med. 1995 Jul; 126(1):81-7. Canzanello VJ, Kraut JA, Holick MF, Johns C, Liu CC, Madias NE. PMID: 7602239.
      View in: PubMed   Mentions: 1     Fields:    Translation:Animals
    59. Expression of gastric and colonic H(+)-K(+)-ATPase in the rat kidney. Am J Physiol. 1995 Apr; 268(4 Pt 2):F581-7. Kraut JA, Starr F, Sachs G, Reuben M. PMID: 7733314.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    60. The role of metabolic acidosis in the pathogenesis of renal osteodystrophy. Adv Ren Replace Ther. 1995 Jan; 2(1):40-51. Kraut JA. PMID: 7614335.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    61. 2.2 A structure of oxy-peroxidase as a model for the transient enzyme: peroxide complex. Nat Struct Biol. 1994 Aug; 1(8):524-31. Miller MA, Shaw A, Kraut J. PMID: 7664080.
      View in: PubMed   Mentions: 9     Fields:    Translation:AnimalsCells
    62. Bone, acid, and osteoporosis. N Engl J Med. 1994 Jun 23; 330(25):1821-2. Kraut JA, Coburn JW. PMID: 8190161.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    63. Basolateral Na(+)-independent Cl(-)-HCO3- exchange in primary cultures of rat IMCD cells. Am J Physiol. 1992 Sep; 263(3 Pt 2):F401-10. Kraut JA, Hart D, Nord EP. PMID: 1415568.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    64. Platelet-activating factor attenuates the arginine vasopressin-induced fall of transepithelial resistance across inner medullary collecting duct monolayers. Miner Electrolyte Metab. 1992; 18(1):9-14. Kraut JA, Mishler DR, Aboolian A, Nagami GT. PMID: 1406507.
      View in: PubMed   Mentions: 1     Fields:    Translation:Animals
    65. Effect of chronic respiratory acidosis on urinary calcium excretion in the dog. Kidney Int. 1990 Sep; 38(3):409-16. Canzanello VJ, Bodvarsson M, Kraut JA, Johns CA, Slatopolsky E, Madias NE. PMID: 2232483.
      View in: PubMed   Mentions: 3     Fields:    Translation:Animals
    66. AVP reduces transepithelial resistance across IMCD cell monolayers. Am J Physiol. 1990 Jun; 258(6 Pt 2):F1561-8. Mishler DR, Kraut JA, Nagami GT. PMID: 1694408.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    67. Modulation of Na+-H+ exchange activity by intracellular Na+, H+, and Li+ in IMCD cells. Am J Physiol. 1988 Aug; 255(2 Pt 2):F331-9. Wall SM, Kraut JA, Muallem S. PMID: 2841873.
      View in: PubMed   Mentions: 5     Fields:    Translation:AnimalsCells
    68. Detection of a Na+-H+ antiporter in cultured rat renal papillary collecting duct cells. Am J Physiol. 1987 Nov; 253(5 Pt 2):F889-95. Wall SM, Muallem S, Kraut JA. PMID: 2825538.
      View in: PubMed   Mentions: 4     Fields:    Translation:Animals
    69. The use of intracatheter instillation of streptokinase in the treatment of recurrent bacterial peritonitis in continuous ambulatory peritoneal dialysis. Am J Kidney Dis. 1987 Jul; 10(1):62-5. Norris KC, Shinaberger JH, Reyes GD, Kraut JA. PMID: 3605085.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    70. Effect of acute acidemia on phosphate uptake by renal proximal tubular brush-border membranes. Am J Physiol. 1986 Nov; 251(5 Pt 2):F889-96. Levine BS, Kraut JA, Mishler DR, Crooks PW. PMID: 3777185.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    71. The effects of metabolic acidosis on bone formation and bone resorption in the rat. Kidney Int. 1986 Nov; 30(5):694-700. Kraut JA, Mishler DR, Singer FR, Goodman WG. PMID: 3784302.
      View in: PubMed   Mentions: 19     Fields:    Translation:Animals
    72. Renal proximal tubular brush-border membrane transport of phosphate with acute acidosis. Adv Exp Med Biol. 1986; 208:145-53. Levine BS, Kraut JA, Mishler DR. PMID: 3105267.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    73. Effect of colchicine and calcitonin on calcemic response to metabolic acidosis. Kidney Int. 1984 Apr; 25(4):608-12. Kraut JA, Mishler DR, Kurokawa K. PMID: 6090754.
      View in: PubMed   Mentions: 5     Fields:    Translation:Animals
    74. Effect of chronic metabolic acidosis on vitamin D metabolism in humans. Kidney Int. 1983 Nov; 24(5):644-8. Kraut JA, Gordon EM, Ransom JC, Horst R, Slatopolsky E, Coburn JW, Kurokawa K. PMID: 6689348.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    75. Parathyroid gland responsiveness to acute hypocalcemia in dialysis osteomalacia. Kidney Int. 1983 May; 23(5):725-30. Kraut JA, Shinaberger JH, Singer FR, Sherrard DJ, Saxton J, Miller JH, Kurokawa K, Coburn JW. PMID: 6876568.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    76. The effect of chronic metabolic acidosis on the end organ responsiveness to parathyroid hormone in man. J Clin Endocrinol Metab. 1983 Mar; 56(3):619-22. Kraut JA, Gordon EM, Ransom JC, Coburn JW, Kurokawa K. PMID: 6296190.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    77. Effect of metabolic acidosis on phosphate transport by the renal brush-border membrane. Biochim Biophys Acta. 1983 Jan 05; 727(1):7-12. Levine BS, Ho K, Kraut JA, Coburn JW, Kurokawa K. PMID: 6824655.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    78. Metabolic acidosis suppresses 25-hydroxyvitamin in D3-1alpha-hydroxylase in the rat kidney. Distinct site and mechanism of action. J Clin Invest. 1982 Jul; 70(1):135-40. Kawashima H, Kraut JA, Kurokawa K. PMID: 6282936.
      View in: PubMed   Mentions: 10     Fields:    Translation:Animals
    79. Failure of increased sodium avidity to facilitate renal acid excretion in dogs fed sulfuric acid. Kidney Int. 1981 Jul; 20(1):50-4. Kraut JA, Wish JB, Sweet SJ, Weinstein SS, Cohen JJ. PMID: 7300112.
      View in: PubMed   Mentions:    Fields:    Translation:Animals
    80. Prevention of hypoxemia during dialysis by the use of sequential isolated ultrafiltration-diffusion dialysis with bicarbonate dialyzate. Clin Nephrol. 1981 Apr; 15(4):181-4. Kraut J, Gafter U, Brautbar N, Miller J, Shinaberger J. PMID: 6786809.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    81. Course of poststreptococcal glomerulonephritis. N Engl J Med. 1977 Jan 27; 296(4):230-1. Sweet SJ, Kraut JA. PMID: 831096.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
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