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hTERT Peptide Fragment GV1001 Prevents the Development of Porphyromonas gingivalis-Induced Periodontal Disease and Systemic Disorders in ApoE-Deficient Mice. Int J Mol Sci. 2024 Jun 01; 25(11).
Chen W, Kim SY, Lee A, Kim YJ, Chang C, Ton-That H, Kim R, Kim S, Park NH. PMID: 38892314.
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Translation:
HumansAnimalsCells
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Molecular basis for dual functions in pilus assembly modulated by the lid of a pilus-specific sortase. J Biol Chem. 2024 Jun; 300(6):107329.
Chang C, Ton-That H, Osipiuk J, Joachimiak A, Das A, Ton-That H. PMID: 38679328; PMCID: PMC11131087.
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Translation:
Cells
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Visualization of a Cell Wall Hydrolase Inhibitor in Fusobacterium nucleatum by Immunofluorescence Microscopy. Methods Mol Biol. 2024; 2727:27-33.
To K, Britton T, Ton-That H. PMID: 37815706.
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PubMed Mentions: Fields:
Translation:
Cells
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Single-Copy Gene Editing of a Cell Wall-Anchored Pilin in Actinomyces oris. Methods Mol Biol. 2024; 2727:125-134.
Bhat AH, Das A, Ton-That H. PMID: 37815713.
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Translation:
Cells
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Detection of Cell Wall-Anchoring Machinery by Immunogold-Labeling Thin-Section Electron Microscopy. Methods Mol Biol. 2024; 2727:145-152.
Chang C, Ton-That H. PMID: 37815715.
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PubMed Mentions: Fields:
Translation:
Cells
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Biological biomarkers of oral cancer. Periodontol 2000. 2023 Dec 10.
Radaic A, Kamarajan P, Cho A, Wang S, Hung GC, Najarzadegan F, Wong DT, Ton-That H, Wang CY, Kapila YL. PMID: 38073011; PMCID: PMC11163022.
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PubMed Mentions:
3 Fields:
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The respiratory enzyme complex Rnf is vital for metabolic adaptation and virulence in Fusobacterium nucleatum. mBio. 2024 Jan 16; 15(1):e0175123.
Britton TA, Wu C, Chen Y-W, Franklin D, Chen Y, Camacho MI, Luong TT, Das A, Ton-That H. PMID: 38059640; PMCID: PMC10790702.
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PubMed Mentions:
1 Fields:
Translation:
HumansAnimalsCells
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The basal and major pilins in the Corynebacterium diphtheriae SpaA pilus adopt similar structures that competitively react with the pilin polymerase. Biopolymers. 2024 Jan; 115(1):e23539.
Sue CK, Cheung NA, Mahoney BJ, McConnell SA, Scully JM, Fu JY, Chang C, Ton-That H, Loo JA, Clubb RT. PMID: 37227047.
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PubMed Mentions:
1 Fields:
Translation:
Cells
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A cryptic oxidoreductase safeguards oxidative protein folding in Corynebacterium diphtheriae. Proc Natl Acad Sci U S A. 2023 02 21; 120(8):e2208675120.
Reardon-Robinson ME, Nguyen MT, Sanchez BC, Osipiuk J, Rückert C, Chang C, Chen B, Nagvekar R, Joachimiak A, Tauch A, Das A, Ton-That H. PMID: 36787356; PMCID: PMC9974433.
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Translation:
Cells
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Genetic Determinants of Hydrogen Sulfide Biosynthesis in Fusobacterium nucleatum Are Required for Bacterial Fitness, Antibiotic Sensitivity, and Virulence. mBio. 2022 10 26; 13(5):e0193622.
Chen YW, Camacho MI, Chen Y, Bhat AH, Chang C, Peluso EA, Wu C, Das A, Ton-That H. PMID: 36073813; PMCID: PMC9600241.
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PubMed Mentions:
5 Fields:
Translation:
HumansAnimalsCells
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A conserved signal-peptidase antagonist modulates membrane homeostasis of actinobacterial sortase critical for surface morphogenesis. Proc Natl Acad Sci U S A. 2022 07 12; 119(28):e2203114119.
Ramirez NA, Wu C, Chang C, Siegel SD, Das A, Ton-That H. PMID: 35787040; PMCID: PMC9282373.
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PubMed Mentions:
1 Fields:
Translation:
Cells
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Topical application of Porphyromonas gingivalis into the gingival pocket in mice leads to chronic‑active infection, periodontitis and systemic inflammation. Int J Mol Med. 2022 08; 50(2).
Kim S, Bando Y, Chang C, Kwon J, Tarverti B, Kim D, Lee SH, Ton-That H, Kim R, Nara PL, Park NH. PMID: 35703359; PMCID: PMC9242655.
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PubMed Mentions:
4 Fields:
Translation:
AnimalsCells
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The Fused Methionine Sulfoxide Reductase MsrAB Promotes Oxidative Stress Defense and Bacterial Virulence in Fusobacterium nucleatum. mBio. 2022 06 28; 13(3):e0302221.
Scheible M, Nguyen CT, Luong TT, Lee JH, Chen YW, Chang C, Wittchen M, Camacho MI, Tiner BL, Wu C, Tauch A, Das A, Ton-That H. PMID: 35420473; PMCID: PMC9239216.
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PubMed Mentions:
4 Fields:
Translation:
HumansAnimalsCells
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A cell wall-anchored glycoprotein confers resistance to cation stress in Actinomyces oris biofilms. Mol Oral Microbiol. 2022 10; 37(5):206-217.
Al Mamun AAM, Wu C, Chang C, Sanchez BC, Das A, Ton-That H. PMID: 35289506; PMCID: PMC9474737.
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PubMed Mentions:
1 Fields:
Translation:
Cells
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Genetic and molecular determinants of polymicrobial interactions in Fusobacterium nucleatum. Proc Natl Acad Sci U S A. 2021 06 08; 118(23).
Wu C, Chen YW, Scheible M, Chang C, Wittchen M, Lee JH, Luong TT, Tiner BL, Tauch A, Das A, Ton-That H. PMID: 34074747; PMCID: PMC8201914.
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PubMed Mentions:
22 Fields:
Translation:
HumansAnimalsCells
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Sortase-assembled pili in Corynebacterium diphtheriae are built using a latch mechanism. Proc Natl Acad Sci U S A. 2021 03 23; 118(12).
McConnell SA, McAllister RA, Amer BR, Mahoney BJ, Sue CK, Chang C, Ton-That H, Clubb RT. PMID: 33723052; PMCID: PMC7999877.
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PubMed Mentions:
3 Fields:
Translation:
Cells
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Anchoring surface proteins to the bacterial cell wall by sortase enzymes: how it started and what we know now. Curr Opin Microbiol. 2021 04; 60:73-79.
Bhat AH, Nguyen MT, Das A, Ton-That H. PMID: 33611145; PMCID: PMC7990056.
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PubMed Mentions:
11 Fields:
Translation:
Cells
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Ribonuclease J-Mediated mRNA Turnover Modulates Cell Shape, Metabolism and Virulence in Corynebacterium diphtheriae. Microorganisms. 2021 Feb 14; 9(2).
Luong TT, Nguyen MT, Chen YW, Chang C, Lee JH, Wittchen M, Ton-That H, Cruz M, Garsin DA, Das A, Tauch A, Ton-That H. PMID: 33672886; PMCID: PMC7917786.
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PubMed Mentions:
3
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Corynebacterium diphtheriae Virulence Analyses Using a Caenorhabditis elegans Model. Curr Protoc Microbiol. 2020 09; 58(1):e109.
Chen YW, Ton-That H. PMID: 32658384; PMCID: PMC7939059.
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PubMed Mentions:
2 Fields:
Translation:
AnimalsCells
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Genetic Manipulation of Corynebacterium diphtheriae and Other Corynebacterium Species. Curr Protoc Microbiol. 2020 09; 58(1):e111.
Chang C, Nguyen MT, Ton-That H. PMID: 32865881; PMCID: PMC8325488.
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PubMed Mentions:
2 Fields:
Translation:
Cells
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Novel structure of the N-terminal helical domain of BibA, a group B streptococcus immunogenic bacterial adhesin. Acta Crystallogr D Struct Biol. 2020 Aug 01; 76(Pt 8):759-770.
Manne K, Chattopadhyay D, Agarwal V, Blom AM, Khare B, Chakravarthy S, Chang C, Ton-That H, Narayana SVL. PMID: 32744258; PMCID: PMC7397492.
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PubMed Mentions:
4 Translation:
Cells
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New Paradigms of Pilus Assembly Mechanisms in Gram-Positive Actinobacteria. Trends Microbiol. 2020 12; 28(12):999-1009.
Ramirez NA, Das A, Ton-That H. PMID: 32499101; PMCID: PMC7657965.
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PubMed Mentions:
13 Fields:
Translation:
HumansCells
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Genetic Manipulation and Virulence Assessment of Fusobacterium nucleatum. Curr Protoc Microbiol. 2020 06; 57(1):e104.
Peluso EA, Scheible M, Ton-That H, Wu C. PMID: 32539234; PMCID: PMC7398570.
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PubMed Mentions:
13 Fields:
Translation:
HumansAnimalsCells
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Kinetics and Optimization of the Lysine-Isopeptide Bond Forming Sortase Enzyme from Corynebacterium diphtheriae. Bioconjug Chem. 2020 06 17; 31(6):1624-1634.
Sue CK, McConnell SA, Ellis-Guardiola K, Muroski JM, McAllister RA, Yu J, Alvarez AI, Chang C, Ogorzalek Loo RR, Loo JA, Ton-That H, Clubb RT. PMID: 32396336; PMCID: PMC8153732.
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PubMed Mentions:
5 Fields:
Translation:
Cells
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A Cell-based Screen in Actinomyces oris to Identify Sortase Inhibitors. Sci Rep. 2020 05 22; 10(1):8520.
Gosschalk JE, Chang C, Sue CK, Siegel SD, Wu C, Kattke MD, Yi SW, Damoiseaux R, Jung ME, Ton-That H, Clubb RT. PMID: 32444661; PMCID: PMC7244523.
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PubMed Mentions:
10 Fields:
Translation:
Cells
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Antimicrobial sensing coupled with cell membrane remodeling mediates antibiotic resistance and virulence in Enterococcus faecalis. Proc Natl Acad Sci U S A. 2019 Dec 26; 116(52):26925-26932.
Khan A, Davlieva M, Panesso D, Rincon S, Miller WR, Diaz L, Reyes J, Cruz MR, Pemberton O, Nguyen AH, Siegel SD, Planet PJ, Narechania A, Latorre M, Rios R, Singh KV, Ton-That H, Garsin DA, Tran TT, Shamoo Y, Arias CA. PMID: 31818937; PMCID: PMC6936494.
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PubMed Mentions:
28 Fields:
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Cell-to-cell interaction requires optimal positioning of a pilus tip adhesin modulated by gram-positive transpeptidase enzymes. Proc Natl Acad Sci U S A. 2019 09 03; 116(36):18041-18049.
Chang C, Wu C, Osipiuk J, Siegel SD, Zhu S, Liu X, Joachimiak A, Clubb RT, Das A, Ton-That H. PMID: 31427528; PMCID: PMC6731673.
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PubMed Mentions:
12 Fields:
Translation:
Cells
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Erratum for Siegel et al., "Structure and Mechanism of LcpA, a Phosphotransferase That Mediates Glycosylation of a Gram-Positive Bacterial Cell Wall-Anchored Protein". mBio. 2019 04 16; 10(2).
Siegel SD, Amer BR, Wu C, Sawaya MR, Gosschalk JE, Clubb RT, Ton-That H. PMID: 30992357; PMCID: PMC6469975.
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PubMed Mentions: Fields:
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Structure and Mechanism of LcpA, a Phosphotransferase That Mediates Glycosylation of a Gram-Positive Bacterial Cell Wall-Anchored Protein. mBio. 2019 02 19; 10(1).
Siegel SD, Amer BR, Wu C, Sawaya MR, Gosschalk JE, Clubb RT, Ton-That H. PMID: 30782654; PMCID: PMC6381275.
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PubMed Mentions:
17 Fields:
Translation:
Cells
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Protein Labeling via a Specific Lysine-Isopeptide Bond Using the Pilin Polymerizing Sortase from Corynebacterium diphtheriae. J Am Chem Soc. 2018 07 11; 140(27):8420-8423.
McConnell SA, Amer BR, Muroski J, Fu J, Chang C, Ogorzalek Loo RR, Loo JA, Osipiuk J, Ton-That H, Clubb RT. PMID: 29927249; PMCID: PMC6230430.
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PubMed Mentions:
16 Fields:
Translation:
Cells
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In vitro reconstitution of sortase-catalyzed pilus polymerization reveals structural elements involved in pilin cross-linking. Proc Natl Acad Sci U S A. 2018 06 12; 115(24):E5477-E5486.
Chang C, Amer BR, Osipiuk J, McConnell SA, Huang IH, Hsieh V, Fu J, Nguyen HH, Muroski J, Flores E, Ogorzalek Loo RR, Loo JA, Putkey JA, Joachimiak A, Das A, Clubb RT, Ton-That H. PMID: 29844180; PMCID: PMC6004493.
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PubMed Mentions:
13 Fields:
Translation:
Cells
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Forward Genetic Dissection of Biofilm Development by Fusobacterium nucleatum: Novel Functions of Cell Division Proteins FtsX and EnvC. mBio. 2018 04 24; 9(2).
Wu C, Al Mamun AAM, Luong TT, Hu B, Gu J, Lee JH, D'Amore M, Das A, Ton-That H. PMID: 29691334; PMCID: PMC5915739.
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PubMed Mentions:
24 Fields:
Translation:
Cells
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Structural Basis of a Thiol-Disulfide Oxidoreductase in the Hedgehog-Forming Actinobacterium Corynebacterium matruchotii. J Bacteriol. 2018 05 01; 200(9).
Luong TT, Tirgar R, Reardon-Robinson ME, Joachimiak A, Osipiuk J, Ton-That H. PMID: 29440253; PMCID: PMC5892113.
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PubMed Mentions:
6 Fields:
Translation:
Cells
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Transcriptome sequencing of the human pathogen Corynebacterium diphtheriae NCTC 13129 provides detailed insights into its transcriptional landscape and into DtxR-mediated transcriptional regulation. BMC Genomics. 2018 01 25; 19(1):82.
Wittchen M, Busche T, Gaspar AH, Lee JH, Ton-That H, Kalinowski J, Tauch A. PMID: 29370758; PMCID: PMC5784534.
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PubMed Mentions:
12 Fields:
Translation:
HumansCells
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Electron Transport Chain Is Biochemically Linked to Pilus Assembly Required for Polymicrobial Interactions and Biofilm Formation in the Gram-Positive Actinobacterium Actinomyces oris. mBio. 2017 06 20; 8(3).
Sanchez BC, Chang C, Wu C, Tran B, Ton-That H. PMID: 28634238; PMCID: PMC5478893.
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PubMed Mentions:
11 Fields:
Translation:
Cells
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Reoxidation of the Thiol-Disulfide Oxidoreductase MdbA by a Bacterial Vitamin K Epoxide Reductase in the Biofilm-Forming Actinobacterium Actinomyces oris. J Bacteriol. 2017 05 15; 199(10).
Luong TT, Reardon-Robinson ME, Siegel SD, Ton-That H. PMID: 28289087; PMCID: PMC5405209.
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PubMed Mentions:
6 Fields:
Translation:
Cells
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Evolution of substrate specificity in a retained enzyme driven by gene loss. Elife. 2017 03 31; 6.
Juárez-Vázquez AL, Edirisinghe JN, Verduzco-Castro EA, Michalska K, Wu C, Noda-García L, Babnigg G, Endres M, Medina-Ruíz S, Santoyo-Flores J, Carrillo-Tripp M, Ton-That H, Joachimiak A, Henry CS, Barona-Gómez F. PMID: 28362260; PMCID: PMC5404923.
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PubMed Mentions:
11 Fields:
Translation:
Cells
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Anchoring of LPXTG-Like Proteins to the Gram-Positive Cell Wall Envelope. Curr Top Microbiol Immunol. 2017; 404:159-175.
Siegel SD, Reardon ME, Ton-That H. PMID: 27097813.
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PubMed Mentions:
24 Fields:
Translation:
Cells
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Biogenesis of the Gram-positive bacterial cell envelope. Curr Opin Microbiol. 2016 12; 34:31-37.
Siegel SD, Liu J, Ton-That H. PMID: 27497053; PMCID: PMC5164837.
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PubMed Mentions:
31 Fields:
Translation:
Cells
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A Type I Signal Peptidase Is Required for Pilus Assembly in the Gram-Positive, Biofilm-Forming Bacterium Actinomyces oris. J Bacteriol. 2016 08 01; 198(15):2064-73.
Siegel SD, Wu C, Ton-That H. PMID: 27215787; PMCID: PMC4944219.
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PubMed Mentions:
13 Fields:
Translation:
Cells
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Role of the Emp Pilus Subunits of Enterococcus faecium in Biofilm Formation, Adherence to Host Extracellular Matrix Components, and Experimental Infection. Infect Immun. 2016 05; 84(5):1491-1500.
Montealegre MC, Singh KV, Somarajan SR, Yadav P, Chang C, Spencer R, Sillanpää J, Ton-That H, Murray BE. PMID: 26930703; PMCID: PMC4862714.
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PubMed Mentions:
14 Fields:
Translation:
AnimalsCells
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CnaA domains in bacterial pili are efficient dissipaters of large mechanical shocks. Proc Natl Acad Sci U S A. 2016 Mar 01; 113(9):2490-5.
Echelman DJ, Alegre-Cebollada J, Badilla CL, Chang C, Ton-That H, Fernández JM. PMID: 26884173; PMCID: PMC4780631.
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PubMed Mentions:
28 Fields:
Translation:
Cells
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Genetics and Cell Morphology Analyses of the Actinomyces oris srtA Mutant. Methods Mol Biol. 2016; 1440:109-22.
Wu C, Reardon-Robinson ME, Ton-That H. PMID: 27311668.
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PubMed Mentions:
5 Fields:
Translation:
Cells
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Disulfide-Bond-Forming Pathways in Gram-Positive Bacteria. J Bacteriol. 2015 Dec 07; 198(5):746-54.
Reardon-Robinson ME, Ton-That H. PMID: 26644434; PMCID: PMC4810614.
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PubMed Mentions:
34 Fields:
Translation:
Cells
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A thiol-disulfide oxidoreductase of the Gram-positive pathogen Corynebacterium diphtheriae is essential for viability, pilus assembly, toxin production and virulence. Mol Microbiol. 2015 Dec; 98(6):1037-50.
Reardon-Robinson ME, Osipiuk J, Jooya N, Chang C, Joachimiak A, Das A, Ton-That H. PMID: 26294390; PMCID: PMC4981772.
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PubMed Mentions:
23 Fields:
Translation:
AnimalsCells
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A Disulfide Bond-forming Machine Is Linked to the Sortase-mediated Pilus Assembly Pathway in the Gram-positive Bacterium Actinomyces oris. J Biol Chem. 2015 Aug 28; 290(35):21393-405.
Reardon-Robinson ME, Osipiuk J, Chang C, Wu C, Jooya N, Joachimiak A, Das A, Ton-That H. PMID: 26170452; PMCID: PMC4571867.
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PubMed Mentions:
20 Fields:
Translation:
HumansCells
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The identification and functional characterization of WxL proteins from Enterococcus faecium reveal surface proteins involved in extracellular matrix interactions. J Bacteriol. 2015 Mar; 197(5):882-92.
Galloway-Peña JR, Liang X, Singh KV, Yadav P, Chang C, La Rosa SL, Shelburne S, Ton-That H, Höök M, Murray BE. PMID: 25512313; PMCID: PMC4325096.
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PubMed Mentions:
19 Fields:
Translation:
HumansAnimalsCells
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Lethality of sortase depletion in Actinomyces oris caused by excessive membrane accumulation of a surface glycoprotein. Mol Microbiol. 2014 Dec; 94(6):1227-41.
Wu C, Huang IH, Chang C, Reardon-Robinson ME, Das A, Ton-That H. PMID: 25230351; PMCID: PMC4262642.
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PubMed Mentions:
31 Fields:
Translation:
Cells
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A slow-forming isopeptide bond in the structure of the major pilin SpaD from Corynebacterium diphtheriae has implications for pilus assembly. Acta Crystallogr D Biol Crystallogr. 2014 May; 70(Pt 5):1190-201.
Kang HJ, Paterson NG, Kim CU, Middleditch M, Chang C, Ton-That H, Baker EN. PMID: 24816089; PMCID: PMC4014117.
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PubMed Mentions:
13 Fields:
Translation:
Cells
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Pilus hijacking by a bacterial coaggregation factor critical for oral biofilm development. Proc Natl Acad Sci U S A. 2014 Mar 11; 111(10):3835-40.
Reardon-Robinson ME, Wu C, Mishra A, Chang C, Bier N, Das A, Ton-That H. PMID: 24567409; PMCID: PMC3956193.
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PubMed Mentions:
28 Fields:
Translation:
HumansCells
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Contribution of individual Ebp Pilus subunits of Enterococcus faecalis OG1RF to pilus biogenesis, biofilm formation and urinary tract infection. PLoS One. 2013; 8(7):e68813.
Sillanpää J, Chang C, Singh KV, Montealegre MC, Nallapareddy SR, Harvey BR, Ton-That H, Murray BE. PMID: 23874774; PMCID: PMC3708956.
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PubMed Mentions:
46 Fields:
Translation:
AnimalsCells
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Pilus gene pool variation and the virulence of Corynebacterium diphtheriae clinical isolates during infection of a nematode. J Bacteriol. 2013 Aug; 195(16):3774-83.
Broadway MM, Rogers EA, Chang C, Huang IH, Dwivedi P, Yildirim S, Schmitt MP, Das A, Ton-That H. PMID: 23772071; PMCID: PMC3754579.
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PubMed Mentions:
21 Fields:
Translation:
HumansAnimalsCells
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Structure of Streptococcus agalactiae tip pilin GBS104: a model for GBS pili assembly and host interactions. Acta Crystallogr D Biol Crystallogr. 2013 Jun; 69(Pt 6):1073-89.
Krishnan V, Dwivedi P, Kim BJ, Samal A, Macon K, Ma X, Mishra A, Doran KS, Ton-That H, Narayana SV. PMID: 23695252; PMCID: PMC3663123.
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PubMed Mentions:
15 Fields:
Translation:
Cells
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Visualization of Gram-positive bacterial pili. Methods Mol Biol. 2013; 966:77-95.
Chang C, Huang IH, Hendrickx AP, Ton-That H. PMID: 23299729.
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PubMed Mentions:
14 Fields:
Translation:
Cells
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Pangenomic study of Corynebacterium diphtheriae that provides insights into the genomic diversity of pathogenic isolates from cases of classical diphtheria, endocarditis, and pneumonia. J Bacteriol. 2012 Jun; 194(12):3199-215.
Trost E, Blom J, Soares Sde C, Huang IH, Al-Dilaimi A, Schröder J, Jaenicke S, Dorella FA, Rocha FS, Miyoshi A, Azevedo V, Schneider MP, Silva A, Camello TC, Sabbadini PS, Santos CS, Santos LS, Hirata R, Mattos-Guaraldi AL, Efstratiou A, Schmitt MP, Ton-That H, Tauch A. PMID: 22505676; PMCID: PMC3370855.
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PubMed Mentions:
67 Fields:
Translation:
HumansCells
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Structural determinants of Actinomyces sortase SrtC2 required for membrane localization and assembly of type 2 fimbriae for interbacterial coaggregation and oral biofilm formation. J Bacteriol. 2012 May; 194(10):2531-9.
Wu C, Mishra A, Reardon ME, Huang IH, Counts SC, Das A, Ton-That H. PMID: 22447896; PMCID: PMC3347213.
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PubMed Mentions:
16 Fields:
Translation:
Cells
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The crystal structure analysis of group B Streptococcus sortase C1: a model for the "lid" movement upon substrate binding. J Mol Biol. 2011 Dec 09; 414(4):563-77.
Khare B, Fu ZQ, Huang IH, Ton-That H, Narayana SV. PMID: 22033482; PMCID: PMC3230703.
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PubMed Mentions:
13 Fields:
Translation:
Cells
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Structural differences between the Streptococcus agalactiae housekeeping and pilus-specific sortases: SrtA and SrtC1. PLoS One. 2011; 6(8):e22995.
Khare B, Krishnan V, Rajashankar KR, I-Hsiu H, Xin M, Ton-That H, Narayana SV. PMID: 21912586; PMCID: PMC3166054.
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PubMed Mentions:
21 Fields:
Translation:
Cells
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Two autonomous structural modules in the fimbrial shaft adhesin FimA mediate Actinomyces interactions with streptococci and host cells during oral biofilm development. Mol Microbiol. 2011 Sep; 81(5):1205-20.
Mishra A, Devarajan B, Reardon ME, Dwivedi P, Krishnan V, Cisar JO, Das A, Narayana SV, Ton-That H. PMID: 21696465; PMCID: PMC3177855.
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PubMed Mentions:
35 Fields:
Translation:
Cells
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Dual function of a tip fimbrillin of Actinomyces in fimbrial assembly and receptor binding. J Bacteriol. 2011 Jul; 193(13):3197-206.
Wu C, Mishra A, Yang J, Cisar JO, Das A, Ton-That H. PMID: 21531799; PMCID: PMC3133261.
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PubMed Mentions:
23 Fields:
Translation:
Cells
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A model for group B Streptococcus pilus type 1: the structure of a 35-kDa C-terminal fragment of the major pilin GBS80. J Mol Biol. 2011 Apr 15; 407(5):731-43.
Vengadesan K, Ma X, Dwivedi P, Ton-That H, Narayana SV. PMID: 21333654; PMCID: PMC3102248.
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PubMed Mentions:
18 Fields:
Translation:
HumansCells
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Cell surface display of minor pilin adhesins in the form of a simple heterodimeric assembly in Corynebacterium diphtheriae. Mol Microbiol. 2011 Mar; 79(5):1236-47.
Chang C, Mandlik A, Das A, Ton-That H. PMID: 21205008; PMCID: PMC3043122.
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PubMed Mentions:
20 Fields:
Translation:
Cells
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Adhesion by pathogenic corynebacteria. Adv Exp Med Biol. 2011; 715:91-103.
Rogers EA, Das A, Ton-That H. PMID: 21557059.
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PubMed Mentions:
25 Fields:
Translation:
HumansCells
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Purification, crystallization and halide phasing of a Streptococcus agalactiae backbone pilin GBS80 fragment. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2010 Dec 01; 66(Pt 12):1666-9.
Vengadesan K, Ma X, Dwivedi P, Ton-That H, Narayana SV. PMID: 21139220; PMCID: PMC2998379.
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PubMed Mentions:
4 Fields:
Translation:
HumansCells
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Preliminary crystallographic study of the Streptococcus agalactiae sortases, sortase A and sortase C1. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2010 Sep 01; 66(Pt 9):1096-100.
Khare B, Samal A, Vengadesan K, Rajashankar KR, Ma X, Huang IH, Ton-That H, Narayana SV. PMID: 20823536; PMCID: PMC2935237.
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PubMed Mentions:
5 Fields:
Translation:
Cells
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Allelic exchange in Actinomyces oris with mCherry fluorescence counterselection. Appl Environ Microbiol. 2010 Sep; 76(17):5987-9.
Wu C, Ton-That H. PMID: 20601506; PMCID: PMC2935053.
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PubMed Mentions:
15 Fields:
Translation:
Cells
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Characterization of the ebp(fm) pilus-encoding operon of Enterococcus faecium and its role in biofilm formation and virulence in a murine model of urinary tract infection. Virulence. 2010 Jul-Aug; 1(4):236-46.
Sillanpää J, Nallapareddy SR, Singh KV, Prakash VP, Fothergill T, Ton-That H, Murray BE. PMID: 20676385; PMCID: PMC2910428.
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PubMed Mentions:
55 Fields:
Translation:
HumansAnimalsCells
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The Actinomyces oris type 2 fimbrial shaft FimA mediates co-aggregation with oral streptococci, adherence to red blood cells and biofilm development. Mol Microbiol. 2010 Aug; 77(4):841-54.
Mishra A, Wu C, Yang J, Cisar JO, Das A, Ton-That H. PMID: 20545853; PMCID: PMC2946971.
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48 Fields:
Translation:
Cells
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The Corynebacterium diphtheriae shaft pilin SpaA is built of tandem Ig-like modules with stabilizing isopeptide and disulfide bonds. Proc Natl Acad Sci U S A. 2009 Oct 06; 106(40):16967-71.
Kang HJ, Paterson NG, Gaspar AH, Ton-That H, Baker EN. PMID: 19805181; PMCID: PMC2761350.
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PubMed Mentions:
67 Fields:
Translation:
Cells
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Acyl enzyme intermediates in sortase-catalyzed pilus morphogenesis in gram-positive bacteria. J Bacteriol. 2009 Sep; 191(18):5603-12.
Guttilla IK, Gaspar AH, Swierczynski A, Swaminathan A, Dwivedi P, Das A, Ton-That H. PMID: 19592583; PMCID: PMC2737948.
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PubMed Mentions:
24 Fields:
Translation:
Cells
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The molecular switch that activates the cell wall anchoring step of pilus assembly in gram-positive bacteria. Proc Natl Acad Sci U S A. 2008 Sep 16; 105(37):14147-52.
Mandlik A, Das A, Ton-That H. PMID: 18779588; PMCID: PMC2734112.
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PubMed Mentions:
67 Fields:
Translation:
Cells
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Pili in Gram-positive bacteria: assembly, involvement in colonization and biofilm development. Trends Microbiol. 2008 Jan; 16(1):33-40.
Mandlik A, Swierczynski A, Das A, Ton-That H. PMID: 18083568; PMCID: PMC2841691.
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PubMed Mentions:
181 Fields:
Translation:
Cells
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Housekeeping sortase facilitates the cell wall anchoring of pilus polymers in Corynebacterium diphtheriae. Mol Microbiol. 2007 Nov; 66(4):961-74.
Swaminathan A, Mandlik A, Swierczynski A, Gaspar A, Das A, Ton-That H. PMID: 17919283; PMCID: PMC2841690.
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PubMed Mentions:
71 Fields:
Translation:
HumansCells
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An IgG-like domain in the minor pilin GBS52 of Streptococcus agalactiae mediates lung epithelial cell adhesion. Structure. 2007 Aug; 15(8):893-903.
Krishnan V, Gaspar AH, Ye N, Mandlik A, Ton-That H, Narayana SV. PMID: 17697995; PMCID: PMC2844079.
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PubMed Mentions:
58 Fields:
Translation:
HumansCells
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Corynebacterium diphtheriae employs specific minor pilins to target human pharyngeal epithelial cells. Mol Microbiol. 2007 Apr; 64(1):111-24.
Mandlik A, Swierczynski A, Das A, Ton-That H. PMID: 17376076; PMCID: PMC2844904.
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PubMed Mentions:
82 Fields:
Translation:
HumansCells
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Sortase-catalyzed assembly of distinct heteromeric fimbriae in Actinomyces naeslundii. J Bacteriol. 2007 Apr; 189(8):3156-65.
Mishra A, Das A, Cisar JO, Ton-That H. PMID: 17277070; PMCID: PMC1855841.
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PubMed Mentions:
58 Fields:
Translation:
HumansCells
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Type III pilus of corynebacteria: Pilus length is determined by the level of its major pilin subunit. J Bacteriol. 2006 Sep; 188(17):6318-25.
Swierczynski A, Ton-That H. PMID: 16923899; PMCID: PMC1595371.
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54 Fields:
Translation:
Cells
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Assembly of distinct pilus structures on the surface of Corynebacterium diphtheriae. J Bacteriol. 2006 Feb; 188(4):1526-33.
Gaspar AH, Ton-That H. PMID: 16452436; PMCID: PMC1367254.
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PubMed Mentions:
69 Fields:
Translation:
Cells
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Bacillus anthracis sortase A (SrtA) anchors LPXTG motif-containing surface proteins to the cell wall envelope. J Bacteriol. 2005 Jul; 187(13):4646-55.
Gaspar AH, Marraffini LA, Glass EM, Debord KL, Ton-That H, Schneewind O. PMID: 15968076; PMCID: PMC1151759.
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PubMed Mentions:
49 Fields:
Translation:
AnimalsCells
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Protein sorting to the cell wall envelope of Gram-positive bacteria. Biochim Biophys Acta. 2004 Nov 11; 1694(1-3):269-78.
Ton-That H, Marraffini LA, Schneewind O. PMID: 15546671.
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PubMed Mentions:
104 Fields:
Translation:
Cells
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The secretion signal of YopN, a regulatory protein of the Yersinia enterocolitica type III secretion pathway. J Bacteriol. 2004 Sep; 186(18):6320-4.
Goss JW, Sorg JA, Ramamurthi KS, Ton-That H, Schneewind O. PMID: 15342604; PMCID: PMC515147.
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PubMed Mentions:
8 Fields:
Translation:
Cells
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Anchoring of surface proteins to the cell wall of Staphylococcus aureus. A conserved arginine residue is required for efficient catalysis of sortase A. J Biol Chem. 2004 Sep 03; 279(36):37763-70.
Marraffini LA, Ton-That H, Zong Y, Narayana SV, Schneewind O. PMID: 15247224.
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PubMed Mentions:
32 Fields:
Translation:
Cells
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Sortases and pilin elements involved in pilus assembly of Corynebacterium diphtheriae. Mol Microbiol. 2004 Jul; 53(1):251-61.
Ton-That H, Marraffini LA, Schneewind O. PMID: 15225319.
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PubMed Mentions:
91 Fields:
Translation:
Cells
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Assembly of pili in Gram-positive bacteria. Trends Microbiol. 2004 May; 12(5):228-34.
Ton-That H, Schneewind O. PMID: 15120142.
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PubMed Mentions:
108 Fields:
Translation:
Cells
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Crystal structures of Staphylococcus aureus sortase A and its substrate complex. J Biol Chem. 2004 Jul 23; 279(30):31383-9.
Zong Y, Bice TW, Ton-That H, Schneewind O, Narayana SV. PMID: 15117963.
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PubMed Mentions:
88 Fields:
Translation:
Cells
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Assembly of pili on the surface of Corynebacterium diphtheriae. Mol Microbiol. 2003 Nov; 50(4):1429-38.
Ton-That H, Schneewind O. PMID: 14622427.
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PubMed Mentions:
170 Fields:
Translation:
Cells
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Anchoring of surface proteins to the cell wall of Staphylococcus aureus. III. Lipid II is an in vivo peptidoglycan substrate for sortase-catalyzed surface protein anchoring. J Biol Chem. 2002 May 03; 277(18):16241-8.
Perry AM, Ton-That H, Mazmanian SK, Schneewind O. PMID: 11856734.
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PubMed Mentions:
95 Fields:
Translation:
Cells
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An iron-regulated sortase anchors a class of surface protein during Staphylococcus aureus pathogenesis. Proc Natl Acad Sci U S A. 2002 Feb 19; 99(4):2293-8.
Mazmanian SK, Ton-That H, Su K, Schneewind O. PMID: 11830639; PMCID: PMC122358.
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PubMed Mentions:
159 Fields:
Translation:
Cells
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Anchoring of surface proteins to the cell wall of Staphylococcus aureus. Cysteine 184 and histidine 120 of sortase form a thiolate-imidazolium ion pair for catalysis. J Biol Chem. 2002 Mar 01; 277(9):7447-52.
Ton-That H, Mazmanian SK, Alksne L, Schneewind O. PMID: 11714722.
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PubMed Mentions:
49 Fields:
Translation:
Cells
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Sortase-catalysed anchoring of surface proteins to the cell wall of Staphylococcus aureus. Mol Microbiol. 2001 Jun; 40(5):1049-57.
Mazmanian SK, Ton-That H, Schneewind O. PMID: 11401711.
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PubMed Mentions:
154 Fields:
Translation:
Cells
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Structure of sortase, the transpeptidase that anchors proteins to the cell wall of Staphylococcus aureus. Proc Natl Acad Sci U S A. 2001 May 22; 98(11):6056-61.
Ilangovan U, Ton-That H, Iwahara J, Schneewind O, Clubb RT. PMID: 11371637; PMCID: PMC33421.
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PubMed Mentions:
106 Fields:
Translation:
Cells
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Assignment of the 1H, 13C and 15N signals of Sortase. J Biomol NMR. 2001 Apr; 19(4):379-80.
Ilangovan U, Iwahara J, Ton-That H, Schneewind O, Clubb RT. PMID: 11370786.
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PubMed Mentions:
5 Fields:
Translation:
Cells
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Anchoring of surface proteins to the cell wall of Staphylococcus aureus. Sortase catalyzed in vitro transpeptidation reaction using LPXTG peptide and NH(2)-Gly(3) substrates. J Biol Chem. 2000 Mar 31; 275(13):9876-81.
Ton-That H, Mazmanian SK, Faull KF, Schneewind O. PMID: 10734144.
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PubMed Mentions:
107 Fields:
Translation:
Cells
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Purification and characterization of sortase, the transpeptidase that cleaves surface proteins of Staphylococcus aureus at the LPXTG motif. Proc Natl Acad Sci U S A. 1999 Oct 26; 96(22):12424-9.
Ton-That H, Liu G, Mazmanian SK, Faull KF, Schneewind O. PMID: 10535938; PMCID: PMC22937.
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PubMed Mentions:
218 Fields:
Translation:
Cells
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Anchor structure of staphylococcal surface proteins. IV. Inhibitors of the cell wall sorting reaction. J Biol Chem. 1999 Aug 20; 274(34):24316-20.
Ton-That H, Schneewind O. PMID: 10446208.
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PubMed Mentions:
64 Fields:
Translation:
Cells
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Staphylococcus aureus sortase, an enzyme that anchors surface proteins to the cell wall. Science. 1999 Jul 30; 285(5428):760-3.
Mazmanian SK, Liu G, Ton-That H, Schneewind O. PMID: 10427003.
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PubMed Mentions:
398 Fields:
Translation:
Cells
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Multiple enzymatic activities of the murein hydrolase from staphylococcal phage phi11. Identification of a D-alanyl-glycine endopeptidase activity. J Biol Chem. 1999 May 28; 274(22):15847-56.
Navarre WW, Ton-That H, Faull KF, Schneewind O. PMID: 10336488.
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PubMed Mentions:
64 Fields:
Translation:
Cells
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Anchor structure of staphylococcal surface proteins. III. Role of the FemA, FemB, and FemX factors in anchoring surface proteins to the bacterial cell wall. J Biol Chem. 1998 Oct 30; 273(44):29143-9.
Ton-That H, Labischinski H, Berger-Bächi B, Schneewind O. PMID: 9786923.
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PubMed Mentions:
27 Fields:
Translation:
Cells
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Anchor structure of staphylococcal surface proteins. II. Cooh-terminal structure of muramidase and amidase-solubilized surface protein. J Biol Chem. 1998 Oct 30; 273(44):29135-42.
Navarre WW, Ton-That H, Faull KF, Schneewind O. PMID: 9786922.
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PubMed Mentions:
23 Fields:
Translation:
Cells
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Anchor structure of staphylococcal surface proteins. A branched peptide that links the carboxyl terminus of proteins to the cell wall. J Biol Chem. 1997 Aug 29; 272(35):22285-92.
Ton-That H, Faull KF, Schneewind O. PMID: 9268378.
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PubMed Mentions:
48 Fields:
Translation:
Cells