Hung Ton-That

Title(s)Professor, Dentistry Dept.
vCardDownload vCard
    Other Positions
    Title(s)Professor, MIMG

    Collapse Research 
    Collapse Research Activities and Funding
    UCLA Dentist-Scientist and Oral Health-Researcher Training Program
    NIH R90DE031531Jul 1, 2021 - Jun 30, 2026
    Role: Principal Investigator
    UCLA Dentist-Scientist and Oral Health-Researcher Training Program
    NIH T90DE030860Jul 1, 2021 - Jun 30, 2026
    Role: Principal Investigator
    Virulence determinants of Fusobacterium nucleatum
    NIH R01DE026758Sep 13, 2017 - Aug 31, 2022
    Role: Principal Investigator
    Post-translocational protein folding in Gram-positive bacteria
    NIH R01DE025015Mar 1, 2015 - Aug 31, 2025
    Role: Principal Investigator
    Pilus assembly in Gram-positive bacteria
    NIH R56AI061381Aug 1, 2012 - Jul 31, 2014
    Role: Principal Investigator
    Molecular Assembly on the Cell Surface of Actinomyces
    NIH R01DE017382Feb 19, 2008 - Aug 31, 2023
    Role: Principal Investigator
    Pilus Assembly in Gram-Positive Bacteria
    NIH R01AI061381Dec 15, 2005 - Nov 30, 2011
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
    Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. A conserved signal-peptidase antagonist modulates membrane homeostasis of actinobacterial sortase critical for surface morphogenesis. Proc Natl Acad Sci U S A. 2022 07 12; 119(28):e2203114119. Ramirez NA, Wu C, Chang C, Siegel SD, Das A, Ton-That H. PMID: 35787040; PMCID: PMC9282373.
      View in: PubMed   Mentions:    Fields:    Translation:Cells
    2. Topical application of Porphyromonas gingivalis into the gingival pocket in mice leads to chronic‑active infection, periodontitis and systemic inflammation. Int J Mol Med. 2022 08; 50(2). Kim S, Bando Y, Chang C, Kwon J, Tarverti B, Kim D, Lee SH, Ton-That H, Kim R, Nara PL, Park NH. PMID: 35703359; PMCID: PMC9242655.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    3. The Fused Methionine Sulfoxide Reductase MsrAB Promotes Oxidative Stress Defense and Bacterial Virulence in Fusobacterium nucleatum. mBio. 2022 06 28; 13(3):e0302221. Scheible M, Nguyen CT, Luong TT, Lee JH, Chen YW, Chang C, Wittchen M, Camacho MI, Tiner BL, Wu C, Tauch A, Das A, Ton-That H. PMID: 35420473; PMCID: PMC9239216.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    4. A cell wall-anchored glycoprotein confers resistance to cation stress in Actinomyces oris biofilms. Mol Oral Microbiol. 2022 Mar 15. Al Mamun AAM, Wu C, Chang C, Sanchez BC, Das A, Ton-That H. PMID: 35289506.
      View in: PubMed   Mentions:    Fields:    
    5. Genetic and molecular determinants of polymicrobial interactions in Fusobacterium nucleatum. Proc Natl Acad Sci U S A. 2021 06 08; 118(23). Wu C, Chen YW, Scheible M, Chang C, Wittchen M, Lee JH, Luong TT, Tiner BL, Tauch A, Das A, Ton-That H. PMID: 34074747; PMCID: PMC8201914.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimalsCells
    6. Sortase-assembled pili in Corynebacterium diphtheriae are built using a latch mechanism. Proc Natl Acad Sci U S A. 2021 03 23; 118(12). McConnell SA, McAllister RA, Amer BR, Mahoney BJ, Sue CK, Chang C, Ton-That H, Clubb RT. PMID: 33723052; PMCID: PMC7999877.
      View in: PubMed   Mentions:    Fields:    Translation:Cells
    7. Anchoring surface proteins to the bacterial cell wall by sortase enzymes: how it started and what we know now. Curr Opin Microbiol. 2021 04; 60:73-79. Bhat AH, Nguyen MT, Das A, Ton-That H. PMID: 33611145; PMCID: PMC7990056.
      View in: PubMed   Mentions: 2     Fields:    Translation:Cells
    8. Ribonuclease J-Mediated mRNA Turnover Modulates Cell Shape, Metabolism and Virulence in Corynebacterium diphtheriae. Microorganisms. 2021 Feb 14; 9(2). Luong TT, Nguyen MT, Chen YW, Chang C, Lee JH, Wittchen M, Ton-That H, Cruz M, Garsin DA, Das A, Tauch A, Ton-That H. PMID: 33672886; PMCID: PMC7917786.
      View in: PubMed   Mentions: 1  
    9. Genetic Manipulation of Corynebacterium diphtheriae and Other Corynebacterium Species. Curr Protoc Microbiol. 2020 09; 58(1):e111. Chang C, Nguyen MT, Ton-That H. PMID: 32865881; PMCID: PMC8325488.
      View in: PubMed   Mentions: 2     Fields:    Translation:Cells
    10. Corynebacterium diphtheriae Virulence Analyses Using a Caenorhabditis elegans Model. Curr Protoc Microbiol. 2020 09; 58(1):e109. Chen YW, Ton-That H. PMID: 32658384; PMCID: PMC7939059.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    11. Novel structure of the N-terminal helical domain of BibA, a group B streptococcus immunogenic bacterial adhesin. Acta Crystallogr D Struct Biol. 2020 Aug 01; 76(Pt 8):759-770. Manne K, Chattopadhyay D, Agarwal V, Blom AM, Khare B, Chakravarthy S, Chang C, Ton-That H, Narayana SVL. PMID: 32744258; PMCID: PMC7397492.
      View in: PubMed   Mentions: 1  Translation:Cells
    12. Genetic Manipulation and Virulence Assessment of Fusobacterium nucleatum. Curr Protoc Microbiol. 2020 06; 57(1):e104. Peluso EA, Scheible M, Ton-That H, Wu C. PMID: 32539234; PMCID: PMC7398570.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimalsCells
    13. New Paradigms of Pilus Assembly Mechanisms in Gram-Positive Actinobacteria. Trends Microbiol. 2020 12; 28(12):999-1009. Ramirez NA, Das A, Ton-That H. PMID: 32499101; PMCID: PMC7657965.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansCells
    14. Kinetics and Optimization of the Lysine-Isopeptide Bond Forming Sortase Enzyme from Corynebacterium diphtheriae. Bioconjug Chem. 2020 06 17; 31(6):1624-1634. Sue CK, McConnell SA, Ellis-Guardiola K, Muroski JM, McAllister RA, Yu J, Alvarez AI, Chang C, Ogorzalek Loo RR, Loo JA, Ton-That H, Clubb RT. PMID: 32396336; PMCID: PMC8153732.
      View in: PubMed   Mentions: 3     Fields:    Translation:Cells
    15. A Cell-based Screen in Actinomyces oris to Identify Sortase Inhibitors. Sci Rep. 2020 05 22; 10(1):8520. Gosschalk JE, Chang C, Sue CK, Siegel SD, Wu C, Kattke MD, Yi SW, Damoiseaux R, Jung ME, Ton-That H, Clubb RT. PMID: 32444661; PMCID: PMC7244523.
      View in: PubMed   Mentions: 6     Fields:    Translation:Cells
    16. Antimicrobial sensing coupled with cell membrane remodeling mediates antibiotic resistance and virulence in Enterococcus faecalis. Proc Natl Acad Sci U S A. 2019 Dec 09. Khan A, Davlieva M, Panesso D, Rincon S, Miller WR, Diaz L, Reyes J, Cruz MR, Pemberton O, Nguyen AH, Siegel SD, Planet PJ, Narechania A, Latorre M, Rios R, Singh KV, Ton-That H, Garsin DA, Tran TT, Shamoo Y, Arias CA. PMID: 31818937; PMCID: PMC6936494.
      View in: PubMed   Mentions: 17     Fields:    
    17. Cell-to-cell interaction requires optimal positioning of a pilus tip adhesin modulated by gram-positive transpeptidase enzymes. Proc Natl Acad Sci U S A. 2019 09 03; 116(36):18041-18049. Chang C, Wu C, Osipiuk J, Siegel SD, Zhu S, Liu X, Joachimiak A, Clubb RT, Das A, Ton-That H. PMID: 31427528; PMCID: PMC6731673.
      View in: PubMed   Mentions: 8     Fields:    Translation:Cells
    18. Erratum for Siegel et al., "Structure and Mechanism of LcpA, a Phosphotransferase That Mediates Glycosylation of a Gram-Positive Bacterial Cell Wall-Anchored Protein". mBio. 2019 04 16; 10(2). Siegel SD, Amer BR, Wu C, Sawaya MR, Gosschalk JE, Clubb RT, Ton-That H. PMID: 30992357; PMCID: PMC6469975.
      View in: PubMed   Mentions:    Fields:    
    19. Structure and Mechanism of LcpA, a Phosphotransferase That Mediates Glycosylation of a Gram-Positive Bacterial Cell Wall-Anchored Protein. mBio. 2019 02 19; 10(1). Siegel SD, Amer BR, Wu C, Sawaya MR, Gosschalk JE, Clubb RT, Ton-That H. PMID: 30782654; PMCID: PMC6381275.
      View in: PubMed   Mentions: 11     Fields:    Translation:Cells
    20. Protein Labeling via a Specific Lysine-Isopeptide Bond Using the Pilin Polymerizing Sortase from Corynebacterium diphtheriae. J Am Chem Soc. 2018 07 11; 140(27):8420-8423. McConnell SA, Amer BR, Muroski J, Fu J, Chang C, Ogorzalek Loo RR, Loo JA, Osipiuk J, Ton-That H, Clubb RT. PMID: 29927249; PMCID: PMC6230430.
      View in: PubMed   Mentions: 14     Fields:    Translation:Cells
    21. In vitro reconstitution of sortase-catalyzed pilus polymerization reveals structural elements involved in pilin cross-linking. Proc Natl Acad Sci U S A. 2018 06 12; 115(24):E5477-E5486. Chang C, Amer BR, Osipiuk J, McConnell SA, Huang IH, Hsieh V, Fu J, Nguyen HH, Muroski J, Flores E, Ogorzalek Loo RR, Loo JA, Putkey JA, Joachimiak A, Das A, Clubb RT, Ton-That H. PMID: 29844180; PMCID: PMC6004493.
      View in: PubMed   Mentions: 9     Fields:    Translation:Cells
    22. Forward Genetic Dissection of Biofilm Development by Fusobacterium nucleatum: Novel Functions of Cell Division Proteins FtsX and EnvC. mBio. 2018 04 24; 9(2). Wu C, Al Mamun AAM, Luong TT, Hu B, Gu J, Lee JH, D'Amore M, Das A, Ton-That H. PMID: 29691334; PMCID: PMC5915739.
      View in: PubMed   Mentions: 12     Fields:    Translation:Cells
    23. Structural Basis of a Thiol-Disulfide Oxidoreductase in the Hedgehog-Forming Actinobacterium Corynebacterium matruchotii. J Bacteriol. 2018 05 01; 200(9). Luong TT, Tirgar R, Reardon-Robinson ME, Joachimiak A, Osipiuk J, Ton-That H. PMID: 29440253; PMCID: PMC5892113.
      View in: PubMed   Mentions: 5     Fields:    Translation:Cells
    24. Transcriptome sequencing of the human pathogen Corynebacterium diphtheriae NCTC 13129 provides detailed insights into its transcriptional landscape and into DtxR-mediated transcriptional regulation. BMC Genomics. 2018 01 25; 19(1):82. Wittchen M, Busche T, Gaspar AH, Lee JH, Ton-That H, Kalinowski J, Tauch A. PMID: 29370758; PMCID: PMC5784534.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansCells
    25. Electron Transport Chain Is Biochemically Linked to Pilus Assembly Required for Polymicrobial Interactions and Biofilm Formation in the Gram-Positive Actinobacterium Actinomyces oris. mBio. 2017 06 20; 8(3). Sanchez BC, Chang C, Wu C, Tran B, Ton-That H. PMID: 28634238; PMCID: PMC5478893.
      View in: PubMed   Mentions: 8     Fields:    Translation:Cells
    26. Reoxidation of the Thiol-Disulfide Oxidoreductase MdbA by a Bacterial Vitamin K Epoxide Reductase in the Biofilm-Forming Actinobacterium Actinomyces oris. J Bacteriol. 2017 05 15; 199(10). Luong TT, Reardon-Robinson ME, Siegel SD, Ton-That H. PMID: 28289087; PMCID: PMC5405209.
      View in: PubMed   Mentions: 6     Fields:    Translation:Cells
    27. Evolution of substrate specificity in a retained enzyme driven by gene loss. Elife. 2017 03 31; 6. Juárez-Vázquez AL, Edirisinghe JN, Verduzco-Castro EA, Michalska K, Wu C, Noda-García L, Babnigg G, Endres M, Medina-Ruíz S, Santoyo-Flores J, Carrillo-Tripp M, Ton-That H, Joachimiak A, Henry CS, Barona-Gómez F. PMID: 28362260; PMCID: PMC5404923.
      View in: PubMed   Mentions: 9     Fields:    Translation:Cells
    28. Anchoring of LPXTG-Like Proteins to the Gram-Positive Cell Wall Envelope. Curr Top Microbiol Immunol. 2017; 404:159-175. Siegel SD, Reardon ME, Ton-That H. PMID: 27097813.
      View in: PubMed   Mentions: 17     Fields:    Translation:Cells
    29. Biogenesis of the Gram-positive bacterial cell envelope. Curr Opin Microbiol. 2016 12; 34:31-37. Siegel SD, Liu J, Ton-That H. PMID: 27497053; PMCID: PMC5164837.
      View in: PubMed   Mentions: 28     Fields:    Translation:Cells
    30. A Type I Signal Peptidase Is Required for Pilus Assembly in the Gram-Positive, Biofilm-Forming Bacterium Actinomyces oris. J Bacteriol. 2016 08 01; 198(15):2064-73. Siegel SD, Wu C, Ton-That H. PMID: 27215787; PMCID: PMC4944219.
      View in: PubMed   Mentions: 10     Fields:    Translation:Cells
    31. Role of the Emp Pilus Subunits of Enterococcus faecium in Biofilm Formation, Adherence to Host Extracellular Matrix Components, and Experimental Infection. Infect Immun. 2016 05; 84(5):1491-1500. Montealegre MC, Singh KV, Somarajan SR, Yadav P, Chang C, Spencer R, Sillanpää J, Ton-That H, Murray BE. PMID: 26930703; PMCID: PMC4862714.
      View in: PubMed   Mentions: 10     Fields:    Translation:AnimalsCells
    32. CnaA domains in bacterial pili are efficient dissipaters of large mechanical shocks. Proc Natl Acad Sci U S A. 2016 Mar 01; 113(9):2490-5. Echelman DJ, Alegre-Cebollada J, Badilla CL, Chang C, Ton-That H, Fernández JM. PMID: 26884173; PMCID: PMC4780631.
      View in: PubMed   Mentions: 27     Fields:    Translation:Cells
    33. Genetics and Cell Morphology Analyses of the Actinomyces oris srtA Mutant. Methods Mol Biol. 2016; 1440:109-22. Wu C, Reardon-Robinson ME, Ton-That H. PMID: 27311668.
      View in: PubMed   Mentions: 3     Fields:    Translation:Cells
    34. Disulfide-Bond-Forming Pathways in Gram-Positive Bacteria. J Bacteriol. 2015 Dec 07; 198(5):746-54. Reardon-Robinson ME, Ton-That H. PMID: 26644434; PMCID: PMC4810614.
      View in: PubMed   Mentions: 30     Fields:    Translation:Cells
    35. A thiol-disulfide oxidoreductase of the Gram-positive pathogen Corynebacterium diphtheriae is essential for viability, pilus assembly, toxin production and virulence. Mol Microbiol. 2015 Dec; 98(6):1037-50. Reardon-Robinson ME, Osipiuk J, Jooya N, Chang C, Joachimiak A, Das A, Ton-That H. PMID: 26294390; PMCID: PMC4981772.
      View in: PubMed   Mentions: 20     Fields:    Translation:AnimalsCells
    36. A Disulfide Bond-forming Machine Is Linked to the Sortase-mediated Pilus Assembly Pathway in the Gram-positive Bacterium Actinomyces oris. J Biol Chem. 2015 Aug 28; 290(35):21393-405. Reardon-Robinson ME, Osipiuk J, Chang C, Wu C, Jooya N, Joachimiak A, Das A, Ton-That H. PMID: 26170452; PMCID: PMC4571867.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansCells
    37. The identification and functional characterization of WxL proteins from Enterococcus faecium reveal surface proteins involved in extracellular matrix interactions. J Bacteriol. 2015 Mar; 197(5):882-92. Galloway-Peña JR, Liang X, Singh KV, Yadav P, Chang C, La Rosa SL, Shelburne S, Ton-That H, Höök M, Murray BE. PMID: 25512313; PMCID: PMC4325096.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansAnimalsCells
    38. Lethality of sortase depletion in Actinomyces oris caused by excessive membrane accumulation of a surface glycoprotein. Mol Microbiol. 2014 Dec; 94(6):1227-41. Wu C, Huang IH, Chang C, Reardon-Robinson ME, Das A, Ton-That H. PMID: 25230351; PMCID: PMC4262642.
      View in: PubMed   Mentions: 26     Fields:    Translation:Cells
    39. A slow-forming isopeptide bond in the structure of the major pilin SpaD from Corynebacterium diphtheriae has implications for pilus assembly. Acta Crystallogr D Biol Crystallogr. 2014 May; 70(Pt 5):1190-201. Kang HJ, Paterson NG, Kim CU, Middleditch M, Chang C, Ton-That H, Baker EN. PMID: 24816089; PMCID: PMC4014117.
      View in: PubMed   Mentions: 13     Fields:    Translation:Cells
    40. Pilus hijacking by a bacterial coaggregation factor critical for oral biofilm development. Proc Natl Acad Sci U S A. 2014 Mar 11; 111(10):3835-40. Reardon-Robinson ME, Wu C, Mishra A, Chang C, Bier N, Das A, Ton-That H. PMID: 24567409; PMCID: PMC3956193.
      View in: PubMed   Mentions: 26     Fields:    Translation:HumansCells
    41. Contribution of individual Ebp Pilus subunits of Enterococcus faecalis OG1RF to pilus biogenesis, biofilm formation and urinary tract infection. PLoS One. 2013; 8(7):e68813. Sillanpää J, Chang C, Singh KV, Montealegre MC, Nallapareddy SR, Harvey BR, Ton-That H, Murray BE. PMID: 23874774; PMCID: PMC3708956.
      View in: PubMed   Mentions: 40     Fields:    Translation:AnimalsCells
    42. Pilus gene pool variation and the virulence of Corynebacterium diphtheriae clinical isolates during infection of a nematode. J Bacteriol. 2013 Aug; 195(16):3774-83. Broadway MM, Rogers EA, Chang C, Huang IH, Dwivedi P, Yildirim S, Schmitt MP, Das A, Ton-That H. PMID: 23772071; PMCID: PMC3754579.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansAnimalsCells
    43. Visualization of Gram-positive bacterial pili. Methods Mol Biol. 2013; 966:77-95. Chang C, Huang IH, Hendrickx AP, Ton-That H. PMID: 23299729.
      View in: PubMed   Mentions: 14     Fields:    Translation:Cells
    44. Pangenomic study of Corynebacterium diphtheriae that provides insights into the genomic diversity of pathogenic isolates from cases of classical diphtheria, endocarditis, and pneumonia. J Bacteriol. 2012 Jun; 194(12):3199-215. Trost E, Blom J, Soares Sde C, Huang IH, Al-Dilaimi A, Schröder J, Jaenicke S, Dorella FA, Rocha FS, Miyoshi A, Azevedo V, Schneider MP, Silva A, Camello TC, Sabbadini PS, Santos CS, Santos LS, Hirata R, Mattos-Guaraldi AL, Efstratiou A, Schmitt MP, Ton-That H, Tauch A. PMID: 22505676; PMCID: PMC3370855.
      View in: PubMed   Mentions: 58     Fields:    Translation:HumansCells
    45. Structural determinants of Actinomyces sortase SrtC2 required for membrane localization and assembly of type 2 fimbriae for interbacterial coaggregation and oral biofilm formation. J Bacteriol. 2012 May; 194(10):2531-9. Wu C, Mishra A, Reardon ME, Huang IH, Counts SC, Das A, Ton-That H. PMID: 22447896; PMCID: PMC3347213.
      View in: PubMed   Mentions: 14     Fields:    Translation:Cells
    46. The crystal structure analysis of group B Streptococcus sortase C1: a model for the "lid" movement upon substrate binding. J Mol Biol. 2011 Dec 09; 414(4):563-77. Khare B, Fu ZQ, Huang IH, Ton-That H, Narayana SV. PMID: 22033482; PMCID: PMC3230703.
      View in: PubMed   Mentions: 12     Fields:    Translation:Cells
    47. Two autonomous structural modules in the fimbrial shaft adhesin FimA mediate Actinomyces interactions with streptococci and host cells during oral biofilm development. Mol Microbiol. 2011 Sep; 81(5):1205-20. Mishra A, Devarajan B, Reardon ME, Dwivedi P, Krishnan V, Cisar JO, Das A, Narayana SV, Ton-That H. PMID: 21696465; PMCID: PMC3177855.
      View in: PubMed   Mentions: 35     Fields:    Translation:Cells
    48. Dual function of a tip fimbrillin of Actinomyces in fimbrial assembly and receptor binding. J Bacteriol. 2011 Jul; 193(13):3197-206. Wu C, Mishra A, Yang J, Cisar JO, Das A, Ton-That H. PMID: 21531799; PMCID: PMC3133261.
      View in: PubMed   Mentions: 22     Fields:    Translation:Cells
    49. Cell surface display of minor pilin adhesins in the form of a simple heterodimeric assembly in Corynebacterium diphtheriae. Mol Microbiol. 2011 Mar; 79(5):1236-47. Chang C, Mandlik A, Das A, Ton-That H. PMID: 21205008; PMCID: PMC3043122.
      View in: PubMed   Mentions: 19     Fields:    Translation:Cells
    50. Adhesion by pathogenic corynebacteria. Adv Exp Med Biol. 2011; 715:91-103. Rogers EA, Das A, Ton-That H. PMID: 21557059.
      View in: PubMed   Mentions: 24     Fields:    Translation:HumansCells
    51. Preliminary crystallographic study of the Streptococcus agalactiae sortases, sortase A and sortase C1. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2010 Sep 01; 66(Pt 9):1096-100. Khare B, Samal A, Vengadesan K, Rajashankar KR, Ma X, Huang IH, Ton-That H, Narayana SV. PMID: 20823536; PMCID: PMC2935237.
      View in: PubMed   Mentions: 4     Fields:    Translation:Cells
    52. Allelic exchange in Actinomyces oris with mCherry fluorescence counterselection. Appl Environ Microbiol. 2010 Sep; 76(17):5987-9. Wu C, Ton-That H. PMID: 20601506; PMCID: PMC2935053.
      View in: PubMed   Mentions: 12     Fields:    Translation:Cells
    53. Characterization of the ebp(fm) pilus-encoding operon of Enterococcus faecium and its role in biofilm formation and virulence in a murine model of urinary tract infection. Virulence. 2010 Jul-Aug; 1(4):236-46. Sillanpää J, Nallapareddy SR, Singh KV, Prakash VP, Fothergill T, Ton-That H, Murray BE. PMID: 20676385; PMCID: PMC2910428.
      View in: PubMed   Mentions: 50     Fields:    Translation:HumansAnimalsCells
    54. The Actinomyces oris type 2 fimbrial shaft FimA mediates co-aggregation with oral streptococci, adherence to red blood cells and biofilm development. Mol Microbiol. 2010 Aug; 77(4):841-54. Mishra A, Wu C, Yang J, Cisar JO, Das A, Ton-That H. PMID: 20545853; PMCID: PMC2946971.
      View in: PubMed   Mentions: 45     Fields:    Translation:Cells
    55. Acyl enzyme intermediates in sortase-catalyzed pilus morphogenesis in gram-positive bacteria. J Bacteriol. 2009 Sep; 191(18):5603-12. Guttilla IK, Gaspar AH, Swierczynski A, Swaminathan A, Dwivedi P, Das A, Ton-That H. PMID: 19592583; PMCID: PMC2737948.
      View in: PubMed   Mentions: 23     Fields:    Translation:Cells
    56. The molecular switch that activates the cell wall anchoring step of pilus assembly in gram-positive bacteria. Proc Natl Acad Sci U S A. 2008 Sep 16; 105(37):14147-52. Mandlik A, Das A, Ton-That H. PMID: 18779588; PMCID: PMC2734112.
      View in: PubMed   Mentions: 73     Fields:    Translation:Cells
    57. Pili in Gram-positive bacteria: assembly, involvement in colonization and biofilm development. Trends Microbiol. 2008 Jan; 16(1):33-40. Mandlik A, Swierczynski A, Das A, Ton-That H. PMID: 18083568; PMCID: PMC2841691.
      View in: PubMed   Mentions: 174     Fields:    Translation:Cells
    58. Housekeeping sortase facilitates the cell wall anchoring of pilus polymers in Corynebacterium diphtheriae. Mol Microbiol. 2007 Nov; 66(4):961-74. Swaminathan A, Mandlik A, Swierczynski A, Gaspar A, Das A, Ton-That H. PMID: 17919283; PMCID: PMC2841690.
      View in: PubMed   Mentions: 71     Fields:    Translation:HumansCells
    59. Corynebacterium diphtheriae employs specific minor pilins to target human pharyngeal epithelial cells. Mol Microbiol. 2007 Apr; 64(1):111-24. Mandlik A, Swierczynski A, Das A, Ton-That H. PMID: 17376076; PMCID: PMC2844904.
      View in: PubMed   Mentions: 83     Fields:    Translation:HumansCells
    60. Sortase-catalyzed assembly of distinct heteromeric fimbriae in Actinomyces naeslundii. J Bacteriol. 2007 Apr; 189(8):3156-65. Mishra A, Das A, Cisar JO, Ton-That H. PMID: 17277070; PMCID: PMC1855841.
      View in: PubMed   Mentions: 54     Fields:    Translation:HumansCells
    61. Assembly of distinct pilus structures on the surface of Corynebacterium diphtheriae. J Bacteriol. 2006 Feb; 188(4):1526-33. Gaspar AH, Ton-That H. PMID: 16452436; PMCID: PMC1367254.
      View in: PubMed   Mentions: 68     Fields:    Translation:Cells
    62. Bacillus anthracis sortase A (SrtA) anchors LPXTG motif-containing surface proteins to the cell wall envelope. J Bacteriol. 2005 Jul; 187(13):4646-55. Gaspar AH, Marraffini LA, Glass EM, Debord KL, Ton-That H, Schneewind O. PMID: 15968076; PMCID: PMC1151759.
      View in: PubMed   Mentions: 51     Fields:    Translation:AnimalsCells
    63. Protein sorting to the cell wall envelope of Gram-positive bacteria. Biochim Biophys Acta. 2004 Nov 11; 1694(1-3):269-78. Ton-That H, Marraffini LA, Schneewind O. PMID: 15546671.
      View in: PubMed   Mentions: 106     Fields:    Translation:Cells
    64. Anchoring of surface proteins to the cell wall of Staphylococcus aureus. A conserved arginine residue is required for efficient catalysis of sortase A. J Biol Chem. 2004 Sep 03; 279(36):37763-70. Marraffini LA, Ton-That H, Zong Y, Narayana SV, Schneewind O. PMID: 15247224.
      View in: PubMed   Mentions: 31     Fields:    Translation:Cells
    65. Sortases and pilin elements involved in pilus assembly of Corynebacterium diphtheriae. Mol Microbiol. 2004 Jul; 53(1):251-61. Ton-That H, Marraffini LA, Schneewind O. PMID: 15225319.
      View in: PubMed   Mentions: 96     Fields:    Translation:Cells
    66. Assembly of pili in Gram-positive bacteria. Trends Microbiol. 2004 May; 12(5):228-34. Ton-That H, Schneewind O. PMID: 15120142.
      View in: PubMed   Mentions: 109     Fields:    Translation:Cells
    67. Crystal structures of Staphylococcus aureus sortase A and its substrate complex. J Biol Chem. 2004 Jul 23; 279(30):31383-9. Zong Y, Bice TW, Ton-That H, Schneewind O, Narayana SV. PMID: 15117963.
      View in: PubMed   Mentions: 83     Fields:    Translation:Cells
    68. Assembly of pili on the surface of Corynebacterium diphtheriae. Mol Microbiol. 2003 Nov; 50(4):1429-38. Ton-That H, Schneewind O. PMID: 14622427.
      View in: PubMed   Mentions: 173     Fields:    Translation:Cells
    69. Anchoring of surface proteins to the cell wall of Staphylococcus aureus. III. Lipid II is an in vivo peptidoglycan substrate for sortase-catalyzed surface protein anchoring. J Biol Chem. 2002 May 03; 277(18):16241-8. Perry AM, Ton-That H, Mazmanian SK, Schneewind O. PMID: 11856734.
      View in: PubMed   Mentions: 94     Fields:    Translation:Cells
    70. An iron-regulated sortase anchors a class of surface protein during Staphylococcus aureus pathogenesis. Proc Natl Acad Sci U S A. 2002 Feb 19; 99(4):2293-8. Mazmanian SK, Ton-That H, Su K, Schneewind O. PMID: 11830639; PMCID: PMC122358.
      View in: PubMed   Mentions: 158     Fields:    Translation:Cells
    71. Anchoring of surface proteins to the cell wall of Staphylococcus aureus. Cysteine 184 and histidine 120 of sortase form a thiolate-imidazolium ion pair for catalysis. J Biol Chem. 2002 Mar 01; 277(9):7447-52. Ton-That H, Mazmanian SK, Alksne L, Schneewind O. PMID: 11714722.
      View in: PubMed   Mentions: 47     Fields:    Translation:Cells
    Hung's Networks
    Concepts (246)
    Derived automatically from this person's publications.
    Co-Authors (2)
    People in Profiles who have published with this person.
    Similar People (60)
    People who share similar concepts with this person.
    Same Department
    Search Department