Vaithilingaraja Arumugaswami

Title(s)Professor, Molecular and Medical Pharmacology
SchoolMedicine
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    1. Mpox Virus and its ocular surface manifestations. Ocul Surf. 2024 Oct; 34:108-121. Chakravarty N, Hemani D, Paravastu R, Ahmad Z, Palani SN, Arumugaswami V, Kumar A. PMID: 38972544; PMCID: PMC11625629.
      View in: PubMed   Mentions: 2     Fields:    
    2. Envelope protein-specific B cell receptors direct lentiviral vector tropism in vivo. Mol Ther. 2024 May 01; 32(5):1311-1327. Takano KA, Wong AAL, Brown R, Situ K, Chua BA, Abu AE, Pham TT, Reyes GC, Ramachandran S, Kamata M, Li MMH, Wu TT, Rao DS, Arumugaswami V, Dorshkind K, Cole S, Morizono K. PMID: 38449314; PMCID: PMC11081870.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimalsCells
    3. Harnessing Biomaterials to Amplify Immunity in Aged Mice through T Memory Stem Cells. ACS Nano. 2024 Mar 05; 18(9):6908-6926. Hasani-Sadrabadi MM, Majedi FS, Zarubova J, Thauland TJ, Arumugaswami V, Hsiai TK, Bouchard LS, Butte MJ, Li S. PMID: 38381620.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    4. Targeting ABCG1 and SREBP-2 mediated cholesterol homeostasis ameliorates Zika virus-induced ocular pathology. iScience. 2024 Mar 15; 27(3):109088. Singh S, Wright RE, Giri S, Arumugaswami V, Kumar A. PMID: 38405605; PMCID: PMC10884761.
      View in: PubMed   Mentions:
    5. A ketogenic diet can mitigate SARS-CoV-2 induced systemic reprogramming and inflammation. Commun Biol. 2023 11 03; 6(1):1115. Palermo A, Li S, Ten Hoeve J, Chellappa A, Morris A, Dillon B, Ma F, Wang Y, Cao E, Shabane B, Acín-Perez R, Petcherski A, Lusis AJ, Hazen S, Shirihai OS, Pellegrini M, Arumugaswami V, Graeber TG, Deb A. PMID: 37923961; PMCID: PMC10624922.
      View in: PubMed   Mentions: 1  Translation:AnimalsCells
    6. The Apolipoprotein E neutralizing antibody inhibits SARS-CoV-2 infection by blocking cellular entry of lipoviral particles. MedComm (2020). 2023 Oct; 4(5):e400. Cui Q, Jeyachandran AV, Garcia G, Qin C, Zhou Y, Zhang M, Wang C, Sun G, Liu W, Zhou T, Feng L, Palmer C, Li Z, Aziz A, Gomperts BN, Feng P, Arumugaswami V, Shi Y. PMID: 37822714; PMCID: PMC10563865.
      View in: PubMed   Mentions: 2  
    7. Differential Susceptibility of Ex Vivo Primary Glioblastoma Tumors to Oncolytic Effect of Modified Zika Virus. Cells. 2023 09 29; 12(19). Garcia G, Chakravarty N, Paiola S, Urena E, Gyani P, Tse C, French SW, Danielpour M, Breunig JJ, Nathanson DA, Arumugaswami V. PMID: 37830597; PMCID: PMC10572118.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    8. Comparative Analysis of Molecular Pathogenic Mechanisms and Antiviral Development Targeting Old and New World Hantaviruses. bioRxiv. 2023 Aug 05. Jeyachandran AV, Irudayam JI, Dubey S, Chakravarty N, Konda B, Shah A, Su B, Wang C, Cui Q, Williams KJ, Srikanth S, Shi Y, Deb A, Damoiseaux R, Stripp BR, Ramaiah A, Arumugaswami V. PMID: 37577539; PMCID: PMC10418258.
      View in: PubMed   Mentions:
    9. Innate immune pathway modulator screen identifies STING pathway activation as a strategy to inhibit multiple families of arbo and respiratory viruses. Cell Rep Med. 2023 05 16; 4(5):101024. Garcia G, Irudayam JI, Jeyachandran AV, Dubey S, Chang C, Castillo Cario S, Price N, Arumugam S, Marquez AL, Shah A, Fanaei A, Chakravarty N, Joshi S, Sinha S, French SW, Parcells MS, Ramaiah A, Arumugaswami V. PMID: 37119814; PMCID: PMC10213809.
      View in: PubMed   Mentions: 7     Fields:    Translation:AnimalsCells
    10. Low complexity domains of the nucleocapsid protein of SARS-CoV-2 form amyloid fibrils. Nat Commun. 2023 04 25; 14(1):2379. Tayeb-Fligelman E, Bowler JT, Tai CE, Sawaya MR, Jiang YX, Garcia G, Griner SL, Cheng X, Salwinski L, Lutter L, Seidler PM, Lu J, Rosenberg GM, Hou K, Abskharon R, Pan H, Zee CT, Boyer DR, Li Y, Anderson DH, Murray KA, Falcon G, Cascio D, Saelices L, Damoiseaux R, Arumugaswami V, Guo F, Eisenberg DS. PMID: 37185252; PMCID: PMC10127185.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCells
    11. Broad-spectrum antiviral inhibitors targeting pandemic potential RNA viruses. bioRxiv. 2023 Jan 20. Garcia G, Irudayam JI, Jeyachandran AV, Dubey S, Chang C, Cario SC, Price N, Arumugam S, Marquez AL, Shah A, Fanaei A, Chakravarty N, Joshi S, Sinha S, French SW, Parcells M, Ramaiah A, Arumugaswami V. PMID: 36711787; PMCID: PMC9882367.
      View in: PubMed   Mentions:
    12. Longitudinal Evaluation of Antibody Persistence in Mother-Infant Dyads After Severe Acute Respiratory Syndrome Coronavirus 2 Infection in Pregnancy. J Infect Dis. 2023 01 11; 227(2):236-245. Cambou MC, Liu CM, Mok T, Fajardo-Martinez V, Paiola SG, Ibarrondo FJ, Kerin T, Fuller T, Tobin NH, Garcia G, Bhattacharya D, Aldrovandi GM, Arumugaswami V, Foo SS, Jung JU, Vasconcelos Z, Brasil P, Brendolin M, Yang OO, Rao R, Nielsen-Saines K. PMID: 36082433; PMCID: PMC9494415.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansCells
    13. Differential Susceptibility of Fetal Retinal Pigment Epithelial Cells, hiPSC- Retinal Stem Cells, and Retinal Organoids to Zika Virus Infection. Viruses. 2023 01 01; 15(1). Contreras D, Garcia G, Jones MK, Martinez LE, Jayakarunakaran A, Gangalapudi V, Tang J, Wu Y, Zhao JJ, Chen Z, Ramaiah A, Tsui I, Kumar A, Nielsen-Saines K, Wang S, Arumugaswami V. PMID: 36680182; PMCID: PMC9864143.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    14. Hippo signaling pathway activation during SARS-CoV-2 infection contributes to host antiviral response. PLoS Biol. 2022 11; 20(11):e3001851. Garcia G, Jeyachandran AV, Wang Y, Irudayam JI, Cario SC, Sen C, Li S, Li Y, Kumar A, Nielsen-Saines K, French SW, Shah PS, Morizono K, Gomperts BN, Deb A, Ramaiah A, Arumugaswami V. PMID: 36346780; PMCID: PMC9642871.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansCells
    15. In Silico Genome Analysis Reveals the Evolution and Potential Impact of SARS-CoV-2 Omicron Structural Changes on Host Immune Evasion and Antiviral Therapeutics. Viruses. 2022 11 06; 14(11). Chauhan D, Chakravarty N, Jeyachandran AV, Jayakarunakaran A, Sinha S, Mishra R, Arumugaswami V, Ramaiah A. PMID: 36366559; PMCID: PMC9697451.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCells
    16. Replication-Deficient Zika Vector-Based Vaccine Provides Maternal and Fetal Protection in Mouse Model. Microbiol Spectr. 2022 10 26; 10(5):e0113722. Garcia G, Chakravarty N, Abu AE, Jeyachandran AV, Takano KA, Brown R, Morizono K, Arumugaswami V. PMID: 36169338; PMCID: PMC9602260.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCellsPHPublic Health
    17. Mitoquinone mesylate targets SARS-CoV-2 infection in preclinical models. bioRxiv. 2022 Jun 23. Petcherski A, Sharma M, Daskou M, Satta S, Vasilopoulos H, Hugo C, Ritou E, Dillon BJ, Fung E, Garcia G, Scafoglio C, Purkayastha A, Gomperts BN, Fishbein GA, Arumugaswami V, Liesa M, Shirihai OS, Kelesidis T. PMID: 35233569; PMCID: PMC8887067.
      View in: PubMed   Mentions: 1  
    18. Draft Genome Sequence of the Earthworm Eudrilus eugeniae. Curr Genomics. 2022 Jun 10; 23(2):118-125. Arumugaperumal A, Sudalaimani DK, Arumugaswami V, Sivasubramaniam S. PMID: 36778974; PMCID: PMC9878837.
      View in: PubMed   Mentions:
    19. Importance of clitellar tissue in the regeneration ability of earthworm Eudrilus eugeniae. Funct Integr Genomics. 2022 Aug; 22(4):1-32. Paul S, Balakrishnan S, Arumugaperumal A, Lathakumari S, Syamala SS, Vijayan V, Durairaj SCJ, Arumugaswami V, Sivasubramaniam S. PMID: 35416560.
      View in: PubMed   Mentions: 1     Fields:    Translation:Animals
    20. Hippo Signaling Pathway Activation during SARS-CoV-2 Infection Contributes to Host Antiviral Response. bioRxiv. 2022 Apr 08. Garcia G, Wang Y, Ignatius Irudayam J, Jeyachandran AV, Cario SC, Sen C, Li S, Li Y, Kumar A, Nielsen-Saines K, French SW, Shah PS, Morizono K, Gomperts B, Deb A, Ramaiah A, Arumugaswami V. PMID: 35441167; PMCID: PMC9016637.
      View in: PubMed   Mentions:
    21. Development of off-the-shelf hematopoietic stem cell-engineered invariant natural killer T cells for COVID-19 therapeutic intervention. Stem Cell Res Ther. 2022 03 21; 13(1):112. Li YR, Dunn ZS, Garcia G, Carmona C, Zhou Y, Lee D, Yu J, Huang J, Kim JT, Arumugaswami V, Wang P, Yang L. PMID: 35313965; PMCID: PMC8935266.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansAnimalsCells
    22. Identification, tissue specific expression analysis and functional characterization of arrestin gene (ARRDC) in the earthworm Eudrilus eugeniae: a molecular hypothesis behind worm photoreception. Mol Biol Rep. 2022 Jun; 49(6):4225-4236. Paul S, Dinesh Kumar SM, Syamala SS, Balakrishnan S, Vijayan V, Arumugaswami V, Sudhakar S. PMID: 35211863.
      View in: PubMed   Mentions:    Fields:    Translation:Animals
    23. Engineered extracellular vesicles antagonize SARS-CoV-2 infection by inhibiting mTOR signaling. Biomater Biosyst. 2022 Jun; 6:100042. Ibrahim AG, Ciullo A, Li C, Garcia G, Peck K, Miyamoto K, Arumugaswami V, Marbán E. PMID: 35187508; PMCID: PMC8841010.
      View in: PubMed   Mentions: 8  
    24. Compound screen identifies the small molecule Q34 as an inhibitor of SARS-CoV-2 infection. iScience. 2022 Jan 21; 25(1):103684. Cui Q, Garcia G, Zhang M, Wang C, Li H, Zhou T, Sun G, Arumugaswami V, Shi Y. PMID: 34977495; PMCID: PMC8704726.
      View in: PubMed   Mentions: 3  
    25. ORAI1 Limits SARS-CoV-2 Infection by Regulating Tonic Type I IFN Signaling. J Immunol. 2022 01 01; 208(1):74-84. Wu B, Ramaiah A, Garcia G, Hasiakos S, Arumugaswami V, Srikanth S. PMID: 34819389; PMCID: PMC8702473.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCells
    26. Neurological pathophysiology of SARS-CoV-2 and pandemic potential RNA viruses: a comparative analysis. FEBS Lett. 2021 12; 595(23):2854-2871. Chakravarty N, Senthilnathan T, Paiola S, Gyani P, Castillo Cario S, Urena E, Jeysankar A, Jeysankar P, Ignatius Irudayam J, Natesan Subramanian S, Lavretsky H, Joshi S, Garcia G, Ramaiah A, Arumugaswami V. PMID: 34757622; PMCID: PMC8652524.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansCells
    27. The systemic inflammatory landscape of COVID-19 in pregnancy: Extensive serum proteomic profiling of mother-infant dyads with in utero SARS-CoV-2. Cell Rep Med. 2021 11 16; 2(11):100453. Foo SS, Cambou MC, Mok T, Fajardo VM, Jung KL, Fuller T, Chen W, Kerin T, Mei J, Bhattacharya D, Choi Y, Wu X, Xia T, Shin WJ, Cranston J, Aldrovandi G, Tobin N, Contreras D, Ibarrondo FJ, Yang O, Yang S, Garner O, Cortado R, Bryson Y, Janzen C, Ghosh S, Devaskar S, Asilnejad B, Moreira ME, Vasconcelos Z, Soni PR, Gibson LC, Brasil P, Comhair SAA, Arumugaswami V, Erzurum SC, Rao R, Jung JU, Nielsen-Saines K. PMID: 34723226; PMCID: PMC8549189.
      View in: PubMed   Mentions: 26     Fields:    Translation:Humans
    28. A CRISPR Activation Screen Identifies an Atypical Rho GTPase That Enhances Zika Viral Entry. Viruses. 2021 10 20; 13(11). Luu AP, Yao Z, Ramachandran S, Azzopardi SA, Miles LA, Schneider WM, Hoffmann HH, Bozzacco L, Garcia G, Gong D, Damoiseaux R, Tang H, Morizono K, Rudin CM, Sun R, Arumugaswami V, Poirier JT, MacDonald MR, Rice CM, Li MMH. PMID: 34834920; PMCID: PMC8623001.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansCells
    29. Targeting the coronavirus nucleocapsid protein through GSK-3 inhibition. Proc Natl Acad Sci U S A. 2021 10 19; 118(42). Liu X, Verma A, Garcia G, Ramage H, Lucas A, Myers RL, Michaelson JJ, Coryell W, Kumar A, Charney AW, Kazanietz MG, Rader DJ, Ritchie MD, Berrettini WH, Schultz DC, Cherry S, Damoiseaux R, Arumugaswami V, Klein PS. PMID: 34593624; PMCID: PMC8594528.
      View in: PubMed   Mentions: 51     Fields:    Translation:HumansCells
    30. SARS-CoV-2 and its beta variant of concern infect human conjunctival epithelial cells and induce differential antiviral innate immune response. Ocul Surf. 2022 01; 23:184-194. Singh S, Garcia G, Shah R, Kramerov AA, Wright RE, Spektor TM, Ljubimov AV, Arumugaswami V, Kumar A. PMID: 34583089; PMCID: PMC8464027.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansCells
    31. Comparative transcriptomic analysis of SARS-CoV-2 infected cell model systems reveals differential innate immune responses. Sci Rep. 2021 Aug 25; 11(1):17146. Sun G, Cui Q, Garcia G, Wang C, Zhang M, Arumugaswami V, Riggs AD, Shi Y. PMID: 34433867; PMCID: PMC8387424.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansCells
    32. Structure-based design of antisense oligonucleotides that inhibit SARS-CoV-2 replication. bioRxiv. 2021 Aug 24. Li Y, Garcia G, Arumugaswami V, Guo F. PMID: 34462746; PMCID: PMC8404888.
      View in: PubMed   Mentions: 1  
    33. A systems-level study reveals host-targeted repurposable drugs against SARS-CoV-2 infection. Mol Syst Biol. 2021 08; 17(8):e10239. Chen F, Shi Q, Pei F, Vogt A, Porritt RA, Garcia G, Gomez AC, Cheng MH, Schurdak ME, Liu B, Chan SY, Arumugaswami V, Stern AM, Taylor DL, Arditi M, Bahar I. PMID: 34339582; PMCID: PMC8328275.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansAnimalsCells
    34. Targeting the Coronavirus Nucleocapsid Protein through GSK-3 Inhibition. medRxiv. 2021 Jul 21. Liu X, Verma A, Garcia G, Ramage H, Myers RL, Lucas A, Michaelson JJ, Coryell W, Kumar A, Charney AW, Kazanietz MG, Rader DJ, Ritchie MD, Berrettini WH, Schultz DC, Cherry S, Damoiseaux R, Arumugaswami V, Klein PS. PMID: 33655282; PMCID: PMC7924307.
      View in: PubMed   Mentions:
    35. Deleterious Effects of SARS-CoV-2 Infection on Human Pancreatic Cells. Front Cell Infect Microbiol. 2021; 11:678482. Shaharuddin SH, Wang V, Santos RS, Gross A, Wang Y, Jawanda H, Zhang Y, Hasan W, Garcia G, Arumugaswami V, Sareen D. PMID: 34282405; PMCID: PMC8285288.
      View in: PubMed   Mentions: 30     Fields:    Translation:HumansCellsPHPublic Health
    36. Development of a blocker of the universal phosphatidylserine- and phosphatidylethanolamine-dependent viral entry pathways. Virology. 2021 08; 560:17-33. Song DH, Garcia G, Situ K, Chua BA, Hong MLO, Do EA, Ramirez CM, Harui A, Arumugaswami V, Morizono K. PMID: 34020328; PMCID: PMC8673400.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansAnimalsCells
    37. ORAI1 establishes resistance to SARS-CoV-2 infection by regulating tonic type I interferon signaling. bioRxiv. 2021 May 04. Wu B, Ramaiah A, Garcia G, Gwack Y, Arumugaswami V, Srikanth S. PMID: 33972946; PMCID: PMC8109209.
      View in: PubMed   Mentions:
    38. A monoclonal antibody against staphylococcal enterotoxin B superantigen inhibits SARS-CoV-2 entry in vitro. Structure. 2021 09 02; 29(9):951-962.e3. Cheng MH, Porritt RA, Rivas MN, Krieger JM, Ozdemir AB, Garcia G, Arumugaswami V, Fries BC, Arditi M, Bahar I. PMID: 33930306; PMCID: PMC8082696.
      View in: PubMed   Mentions: 23     Fields:    Translation:HumansCells
    39. SARS-CoV-2 infection of primary human lung epithelium for COVID-19 modeling and drug discovery. Cell Rep. 2021 05 04; 35(5):109055. Mulay A, Konda B, Garcia G, Yao C, Beil S, Villalba JM, Koziol C, Sen C, Purkayastha A, Kolls JK, Pociask DA, Pessina P, de Aja JS, Garcia-de-Alba C, Kim CF, Gomperts B, Arumugaswami V, Stripp BR. PMID: 33905739; PMCID: PMC8043574.
      View in: PubMed   Mentions: 146     Fields:    Translation:HumansCells
    40. SARS-CoV-2 infection rewires host cell metabolism and is potentially susceptible to mTORC1 inhibition. Nat Commun. 2021 03 25; 12(1):1876. Mullen PJ, Garcia G, Purkayastha A, Matulionis N, Schmid EW, Momcilovic M, Sen C, Langerman J, Ramaiah A, Shackelford DB, Damoiseaux R, French SW, Plath K, Gomperts BN, Arumugaswami V, Christofk HR. PMID: 33767183; PMCID: PMC7994801.
      View in: PubMed   Mentions: 73     Fields:    Translation:HumansAnimalsCells
    41. Antiviral drug screen identifies DNA-damage response inhibitor as potent blocker of SARS-CoV-2 replication. Cell Rep. 2021 04 06; 35(1):108940. Garcia G, Sharma A, Ramaiah A, Sen C, Purkayastha A, Kohn DB, Parcells MS, Beck S, Kim H, Bakowski MA, Kirkpatrick MG, Riva L, Wolff KC, Han B, Yuen C, Ulmert D, Purbey PK, Scumpia P, Beutler N, Rogers TF, Chatterjee AK, Gabriel G, Bartenschlager R, Gomperts B, Svendsen CN, Betz UAK, Damoiseaux RD, Arumugaswami V. PMID: 33784499; PMCID: PMC7969873.
      View in: PubMed   Mentions: 63     Fields:    Translation:HumansAnimalsCells
    42. Metabolic reprogramming and epigenetic changes of vital organs in SARS-CoV-2-induced systemic toxicity. JCI Insight. 2021 01 25; 6(2). Li S, Ma F, Yokota T, Garcia G, Palermo A, Wang Y, Farrell C, Wang YC, Wu R, Zhou Z, Pan C, Morselli M, Teitell MA, Ryazantsev S, Fishbein GA, Hoeve JT, Arboleda VA, Bloom J, Dillon B, Pellegrini M, Lusis AJ, Graeber TG, Arumugaswami V, Deb A. PMID: 33284134; PMCID: PMC7934846.
      View in: PubMed   Mentions: 49     Fields:    Translation:HumansAnimalsCells
    43. Systemic diseases and the cornea. Exp Eye Res. 2021 03; 204:108455. Shah R, Amador C, Tormanen K, Ghiam S, Saghizadeh M, Arumugaswami V, Kumar A, Kramerov AA, Ljubimov AV. PMID: 33485845; PMCID: PMC7946758.
      View in: PubMed   Mentions: 31     Fields:    Translation:HumansCells
    44. ApoE-Isoform-Dependent SARS-CoV-2 Neurotropism and Cellular Response. Cell Stem Cell. 2021 02 04; 28(2):331-342.e5. Wang C, Zhang M, Garcia G, Tian E, Cui Q, Chen X, Sun G, Wang J, Arumugaswami V, Shi Y. PMID: 33450186; PMCID: PMC7832490.
      View in: PubMed   Mentions: 122     Fields:    Translation:HumansAnimalsCells
    45. The transcriptome of anterior regeneration in earthworm Eudrilus eugeniae. Mol Biol Rep. 2021 Jan; 48(1):259-283. Paul S, Balakrishnan S, Arumugaperumal A, Lathakumari S, Syamala SS, Arumugaswami V, Sivasubramaniam S. PMID: 33306150.
      View in: PubMed   Mentions: 8     Fields:    Translation:AnimalsCells
    46. A monoclonal antibody against staphylococcal enterotoxin B superantigen inhibits SARS-CoV-2 entry in vitro. bioRxiv. 2020 Nov 24. Cheng MH, Porritt RA, Rivas MN, Krieger JM, Ozdemir AB, Garcia G, Arumugaswami V, Fries BC, Arditi M, Bahar I. PMID: 33269352; PMCID: PMC7709177.
      View in: PubMed   Mentions: 1  
    47. Direct Exposure to SARS-CoV-2 and Cigarette Smoke Increases Infection Severity and Alters the Stem Cell-Derived Airway Repair Response. Cell Stem Cell. 2020 12 03; 27(6):869-875.e4. Purkayastha A, Sen C, Garcia G, Langerman J, Shia DW, Meneses LK, Vijayaraj P, Durra A, Koloff CR, Freund DR, Chi J, Rickabaugh TM, Mulay A, Konda B, Sim MS, Stripp BR, Plath K, Arumugaswami V, Gomperts BN. PMID: 33259798; PMCID: PMC7670932.
      View in: PubMed   Mentions: 50     Fields:    Translation:HumansCells
    48. Cold atmospheric plasma for SARS-CoV-2 inactivation. Phys Fluids (1994). 2020 Nov 01; 32(11):111702. Chen Z, Garcia G, Arumugaswami V, Wirz RE. PMID: 33244211; PMCID: PMC7684674.
      View in: PubMed   Mentions: 41  
    49. Direct exposure to SARS-CoV-2 and cigarette smoke increases infection severity and alters the stem cell-derived airway repair response. bioRxiv. 2020 Jul 29. Purkayastha A, Sen C, Garcia G, Langerman J, Vijayaraj P, Shia DW, Meneses LK, Rickabaugh TM, Mulay A, Konda B, Sim MS, Stripp BR, Plath K, Arumugaswami V, Gomperts BN. PMID: 32766588; PMCID: PMC7402049.
      View in: PubMed   Mentions:
    50. SARS-CoV-2 infection of primary human lung epithelium for COVID-19 modeling and drug discovery. bioRxiv. 2020 Jun 29. Mulay A, Konda B, Garcia G, Yao C, Beil S, Sen C, Purkayastha A, Kolls JK, Pociask DA, Pessina P, de Aja JS, Garcia-de-Alba C, Kim CF, Gomperts B, Arumugaswami V, Stripp BR. PMID: 32637946; PMCID: PMC7337376.
      View in: PubMed   Mentions:
    51. Human iPSC-Derived Cardiomyocytes Are Susceptible to SARS-CoV-2 Infection. Cell Rep Med. 2020 07 21; 1(4):100052. Sharma A, Garcia G, Wang Y, Plummer JT, Morizono K, Arumugaswami V, Svendsen CN. PMID: 32835305; PMCID: PMC7323681.
      View in: PubMed   Mentions: 193     Fields:    
    52. Human iPSC-Derived Cardiomyocytes are Susceptible to SARS-CoV-2 Infection. bioRxiv. 2020 Apr 21. Sharma A, Garcia G, Arumugaswami V, Svendsen CN. PMID: 32511402; PMCID: PMC7263549.
      View in: PubMed   Mentions:
    53. Zika Virus Mucosal Infection Provides Protective Immunity. J Virol. 2020 04 16; 94(9). Martínez LE, Garcia G, Contreras D, Gong D, Sun R, Arumugaswami V. PMID: 32051274; PMCID: PMC7163142.
      View in: PubMed   Mentions: 9     Fields:    Translation:AnimalsCellsPHPublic Health
    54. AMP-Activated Protein Kinase Restricts Zika Virus Replication in Endothelial Cells by Potentiating Innate Antiviral Responses and Inhibiting Glycolysis. J Immunol. 2020 04 01; 204(7):1810-1824. Singh S, Singh PK, Suhail H, Arumugaswami V, Pellett PE, Giri S, Kumar A. PMID: 32086387; PMCID: PMC7310572.
      View in: PubMed   Mentions: 49     Fields:    Translation:HumansCells
    55. Hippo Signaling Pathway Has a Critical Role in Zika Virus Replication and in the Pathogenesis of Neuroinflammation. Am J Pathol. 2020 04; 190(4):844-861. Garcia G, Paul S, Beshara S, Ramanujan VK, Ramaiah A, Nielsen-Saines K, Li MMH, French SW, Morizono K, Kumar A, Arumugaswami V. PMID: 32035058; PMCID: PMC7163250.
      View in: PubMed   Mentions: 27     Fields:    Translation:AnimalsCells
    56. Differential Metabolic Reprogramming by Zika Virus Promotes Cell Death in Human versus Mosquito Cells. Cell Metab. 2019 05 07; 29(5):1206-1216.e4. Thaker SK, Chapa T, Garcia G, Gong D, Schmid EW, Arumugaswami V, Sun R, Christofk HR. PMID: 30827860; PMCID: PMC6818653.
      View in: PubMed   Mentions: 47     Fields:    Translation:HumansAnimalsCells
    57. Visual function in infants with antenatal Zika virus exposure. J AAPOS. 2018 12; 22(6):452-456.e1. Zin AA, Tsui I, Rossetto JD, Gaw SL, Neves LM, Zin OA, Haefeli L, Barros Silveira Filho JC, Adachi K, Vinicius da Silva Pone M, Pone SM, Molleri N, Pereira JP, Belfort R, Arumugaswami V, Vasconcelos Z, Brasil P, Nielsen-Saines K, Lopes Moreira ME. PMID: 30359768; PMCID: PMC6289819.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansCells
    58. Eye Findings in Infants With Suspected or Confirmed Antenatal Zika Virus Exposure. Pediatrics. 2018 10; 142(4). Tsui I, Moreira MEL, Rossetto JD, Vasconcelos Z, Gaw SL, Neves LM, Zin OA, Haefeli L, Silveira Filho JCB, Gomes SC, Adachi K, Pone MVDS, Pone SM, Pereira JP, Belfort R, Arumugaswami V, Brasil P, Nielsen-Saines K, Zin AA. PMID: 30213843; PMCID: PMC6317824.
      View in: PubMed   Mentions: 22     Fields:    Translation:HumansCellsPHPublic Health
    59. HSP70 Copurifies with Zika Virus Particles. Virology. 2018 09; 522:228-233. Khachatoorian R, Cohn W, Buzzanco A, Riahi R, Arumugaswami V, Dasgupta A, Whitelegge JP, French SW. PMID: 30053656.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansAnimalsCells
    60. Determination of system level alterations in host transcriptome due to Zika virus (ZIKV) Infection in retinal pigment epithelium. Sci Rep. 2018 07 25; 8(1):11209. Singh PK, Khatri I, Jha A, Pretto CD, Spindler KR, Arumugaswami V, Giri S, Kumar A, Bhasin MK. PMID: 30046058; PMCID: PMC6060127.
      View in: PubMed   Mentions: 28     Fields:    Translation:HumansCells
    61. Oncoprotein Stathmin Modulates Sensitivity to Apoptosis in Hepatocellular Carcinoma Cells During Hepatitis C Viral Replication. J Cell Death. 2018; 11:1179066018785141. Lu NT, Liu NM, Patel D, Vu JQ, Liu L, Kim CY, Cho P, Khachatoorian R, Patel N, Magyar CE, Ganapathy E, Arumugaswami V, Dasgupta A, French SW. PMID: 30034249; PMCID: PMC6047100.
      View in: PubMed   Mentions: 3  
    62. High-Throughput Fitness Profiling of Zika Virus E Protein Reveals Different Roles for Glycosylation during Infection of Mammalian and Mosquito Cells. iScience. 2018 Mar 23; 1:97-111. Gong D, Zhang TH, Zhao D, Du Y, Chapa TJ, Shi Y, Wang L, Contreras D, Zeng G, Shi PY, Wu TT, Arumugaswami V, Sun R. PMID: 30227960; PMCID: PMC6135943.
      View in: PubMed   Mentions: 20  
    63. Hepatic Tm6sf2 overexpression affects cellular ApoB-trafficking, plasma lipid levels, hepatic steatosis and atherosclerosis. Hum Mol Genet. 2017 07 15; 26(14):2719-2731. Ehrhardt N, Doche ME, Chen S, Mao HZ, Walsh MT, Bedoya C, Guindi M, Xiong W, Ignatius Irudayam J, Iqbal J, Fuchs S, French SW, Mahmood Hussain M, Arditi M, Arumugaswami V, Péterfy M. PMID: 28449094; PMCID: PMC5886214.
      View in: PubMed   Mentions: 30     Fields:    Translation:HumansAnimalsCells
    64. Function of translationally controlled tumor protein (TCTP) in Eudrilus eugeniae regeneration. PLoS One. 2017; 12(4):e0175319. Subramanian ER, Gopi Daisy N, Sudalaimani DK, Ramamoorthy K, Balakrishnan S, Selvan Christyraj JD, Arumugaswami V, Sivasubramaniam S. PMID: 28403226; PMCID: PMC5389791.
      View in: PubMed   Mentions: 5     Fields:    Translation:AnimalsCells
    65. Comparative analysis of protein evolution in the genome of pre-epidemic and epidemic Zika virus. Infect Genet Evol. 2017 07; 51:74-85. Ramaiah A, Dai L, Contreras D, Sinha S, Sun R, Arumugaswami V. PMID: 28315476.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansAnimalsCellsPHPublic Health
    66. Systematic identification of anti-interferon function on hepatitis C virus genome reveals p7 as an immune evasion protein. Proc Natl Acad Sci U S A. 2017 02 21; 114(8):2018-2023. Qi H, Chu V, Wu NC, Chen Z, Truong S, Brar G, Su SY, Du Y, Arumugaswami V, Olson CA, Chen SH, Lin CY, Wu TT, Sun R. PMID: 28159892; PMCID: PMC5338388.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansCells
    67. Erratum to: Effective endothelial cell and human pluripotent stem cell interactions generate functional insulin-producing beta cells. Diabetologia. 2016 12; 59(12):2730. Talavera-Adame D, Woolcott OO, Ignatius-Irudayam J, Arumugaswami V, Geller DH, Dafoe DC. PMID: 27752711; PMCID: PMC6828511.
      View in: PubMed   Mentions:    Fields:    
    68. Effective endothelial cell and human pluripotent stem cell interactions generate functional insulin-producing beta cells. Diabetologia. 2016 11; 59(11):2378-2386. Talavera-Adame D, Woolcott OO, Ignatius-Irudayam J, Arumugaswami V, Geller DH, Dafoe DC. PMID: 27567623; PMCID: PMC5506104.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansAnimalsCells
    69. Zika Virus Infectious Cell Culture System and the In Vitro Prophylactic Effect of Interferons. J Vis Exp. 2016 08 23; (114). Contreras D, Arumugaswami V. PMID: 27584546; PMCID: PMC5091946.
      View in: PubMed   Mentions: 22     Fields:    Translation:HumansAnimalsCellsPHPublic Health
    70. Studies on regeneration of central nervous system and social ability of the earthworm Eudrilus eugeniae. Invert Neurosci. 2016 09; 16(3):6. Gopi Daisy N, Subramanian ER, Selvan Christyraj JD, Sudalai Mani DK, Selvan Christyraj JR, Ramamoorthy K, Arumugaswami V, Sivasubramaniam S. PMID: 27279085.
      View in: PubMed   Mentions: 3     Fields:    Translation:Animals
    71. Allosteric heat shock protein 70 inhibitors block hepatitis C virus assembly. Int J Antimicrob Agents. 2016 Apr; 47(4):289-96. Khachatoorian R, Riahi R, Ganapathy E, Shao H, Wheatley NM, Sundberg C, Jung CL, Ruchala P, Dasgupta A, Arumugaswami V, Gestwicki JE, French SW. PMID: 27013001; PMCID: PMC4833571.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansCells
    72. Ebolavirus evolves in human to minimize the detection by immune cells by accumulating adaptive mutations. Virusdisease. 2016 Jun; 27(2):136-44. Ramaiah A, Arumugaswami V. PMID: 27366764; PMCID: PMC4908996.
      View in: PubMed   Mentions: 1  
    73. Profile of Inflammation-associated genes during Hepatic Differentiation of Human Pluripotent Stem Cells. Data Brief. 2015 Dec; 5:871-8. Ignatius Irudayam J, Contreras D, Spurka L, Ren S, Kanagavel V, Ramaiah A, Annamalai A, French SW, Klein AS, Funari V, Arumugaswami V. PMID: 26702414; PMCID: PMC4669432.
      View in: PubMed   Mentions: 4  
    74. Characterization of type I interferon pathway during hepatic differentiation of human pluripotent stem cells and hepatitis C virus infection. Stem Cell Res. 2015 Sep; 15(2):354-364. Irudayam JI, Contreras D, Spurka L, Subramanian A, Allen J, Ren S, Kanagavel V, Nguyen Q, Ramaiah A, Ramamoorthy K, French SW, Klein AS, Funari V, Arumugaswami V. PMID: 26313525; PMCID: PMC4600668.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansCells
    75. Low-Dose Irradiation Enhances Gene Targeting in Human Pluripotent Stem Cells. Stem Cells Transl Med. 2015 Sep; 4(9):998-1010. Hatada S, Subramanian A, Mandefro B, Ren S, Kim HW, Tang J, Funari V, Baloh RH, Sareen D, Arumugaswami V, Svendsen CN. PMID: 26185257; PMCID: PMC4542875.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansCells
    76. Structural characterization of the HSP70 interaction domain of the hepatitis C viral protein NS5A. Virology. 2015 Jan 15; 475:46-55. Khachatoorian R, Ruchala P, Waring A, Jung CL, Ganapathy E, Wheatley N, Sundberg C, Arumugaswami V, Dasgupta A, French SW. PMID: 25462345; PMCID: PMC4284078.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansCells
    77. A comprehensive functional map of the hepatitis C virus genome provides a resource for probing viral proteins. mBio. 2014 Sep 30; 5(5):e01469-14. Remenyi R, Qi H, Su SY, Chen Z, Wu NC, Arumugaswami V, Truong S, Chu V, Stokelman T, Lo HH, Olson CA, Wu TT, Chen SH, Lin CY, Sun R. PMID: 25271282; PMCID: PMC4196222.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansCells
    78. Leptin enhances endothelial cell differentiation and angiogenesis in murine embryonic stem cells. Microvasc Res. 2015 Jan; 97:65-74. Kurtovic S, Ng TT, Gupta A, Arumugaswami V, Chaiboonma KL, Aminzadeh MA, Makkar R, Dafoe DC, Talavera-Adame D. PMID: 25250519.
      View in: PubMed   Mentions: 9     Fields:    Translation:AnimalsCells
    79. A protocol for analyzing hepatitis C virus replication. J Vis Exp. 2014 Jun 26; (88):e51362. Ren S, Contreras D, Arumugaswami V. PMID: 24998302; PMCID: PMC4206077.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    80. The NS5A-binding heat shock proteins HSC70 and HSP70 play distinct roles in the hepatitis C viral life cycle. Virology. 2014 Apr; 454-455:118-27. Khachatoorian R, Ganapathy E, Ahmadieh Y, Wheatley N, Sundberg C, Jung CL, Arumugaswami V, Raychaudhuri S, Dasgupta A, French SW. PMID: 24725938; PMCID: PMC4011396.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansCells
    81. Identification and comparative analysis of hepatitis C virus-host cell protein interactions. Mol Biosyst. 2013 Dec; 9(12):3199-209. Dolan PT, Zhang C, Khadka S, Arumugaswami V, Vangeloff AD, Heaton NS, Sahasrabudhe S, Randall G, Sun R, LaCount DJ. PMID: 24136289; PMCID: PMC4171131.
      View in: PubMed   Mentions: 22     Fields:    Translation:HumansCells
    82. Bone morphogenetic protein-2/-4 upregulation promoted by endothelial cells in coculture enhances mouse embryoid body differentiation. Stem Cells Dev. 2013 Dec 15; 22(24):3252-60. Talavera-Adame D, Gupta A, Kurtovic S, Chaiboonma KL, Arumugaswami V, Dafoe DC. PMID: 23924071; PMCID: PMC3868407.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimalsCells
    83. A new system to measure and compare hepatitis C virus replication capacity using full-length, replication competent viruses. J Virol Methods. 2013 Dec; 194(1-2):82-8. Lassmann B, Arumugaswami V, Chew KW, Lewis MJ. PMID: 23973740.
      View in: PubMed   Mentions:    Fields:    Translation:Cells
    84. Systematic analysis of enhancer and critical cis-acting RNA elements in the protein-encoding region of the hepatitis C virus genome. J Virol. 2013 May; 87(10):5678-96. Chu D, Ren S, Hu S, Wang WG, Subramanian A, Contreras D, Kanagavel V, Chung E, Ko J, Amirtham Jacob Appadorai RS, Sinha S, Jalali Z, Hardy DW, French SW, Arumugaswami V. PMID: 23487449; PMCID: PMC3648135.
      View in: PubMed   Mentions: 22     Fields:    Translation:HumansCells
    85. Mitochondrial NDUFS3 regulates the ROS-mediated onset of metabolic switch in transformed cells. Biol Open. 2013 Mar 15; 2(3):295-305. Suhane S, Kanzaki H, Arumugaswami V, Murali R, Ramanujan VK. PMID: 23519235; PMCID: PMC3603411.
      View in: PubMed   Mentions: 29     Fields:    
    86. Divergent antiviral effects of bioflavonoids on the hepatitis C virus life cycle. Virology. 2012 Nov 25; 433(2):346-55. Khachatoorian R, Arumugaswami V, Raychaudhuri S, Yeh GK, Maloney EM, Wang J, Dasgupta A, French SW. PMID: 22975673; PMCID: PMC3478964.
      View in: PubMed   Mentions: 34     Fields:    Translation:HumansCells
    87. A cell-permeable hairpin peptide inhibits hepatitis C viral nonstructural protein 5A-mediated translation and virus production. Hepatology. 2012 Jun; 55(6):1662-72. Khachatoorian R, Arumugaswami V, Ruchala P, Raychaudhuri S, Maloney EM, Miao E, Dasgupta A, French SW. PMID: 22183951; PMCID: PMC3345309.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansCells
    88. The virion-associated open reading frame 49 of murine gammaherpesvirus 68 promotes viral replication both in vitro and in vivo as a derepressor of RTA. J Virol. 2012 Jan; 86(2):1109-18. Noh CW, Cho HJ, Kang HR, Jin HY, Lee S, Deng H, Wu TT, Arumugaswami V, Sun R, Song MJ. PMID: 22090108; PMCID: PMC3255801.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansAnimalsCells
    89. The heat shock protein inhibitor Quercetin attenuates hepatitis C virus production. Hepatology. 2009 Dec; 50(6):1756-64. Gonzalez O, Fontanes V, Raychaudhuri S, Loo R, Loo J, Arumugaswami V, Sun R, Dasgupta A, French SW. PMID: 19839005; PMCID: PMC3846025.
      View in: PubMed   Mentions: 78     Fields:    Translation:HumansCells
    90. Latency of Marek's disease virus (MDV) in a reticuloendotheliosis virus-transformed T-cell line. I: uptake and structure of the latent MDV genome. Avian Dis. 2009 Jun; 53(2):149-55. Arumugaswami V, Kumar PM, Konjufca V, Dienglewicz RL, Reddy SM, Parcells MS. PMID: 19630217.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    91. Latency of Marek's disease virus (MDV) in a reticuloendotheliosis virus-transformed T-cell line. II: expression of the latent MDV genome. Avian Dis. 2009 Jun; 53(2):156-65. Arumugaswami V, Kumar PM, Konjufca V, Dienglewicz RL, Reddy SM, Parcells MS. PMID: 19630218.
      View in: PubMed   Mentions: 9     Fields:    Translation:AnimalsCells
    92. Identification and functional characterization of the left origin of lytic replication of murine gammaherpesvirus 68. Virology. 2009 May 10; 387(2):285-95. Gong D, Qi J, Arumugaswami V, Sun R, Deng H. PMID: 19285330; PMCID: PMC2715915.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansAnimalsCells
    93. High-resolution functional profiling of a gammaherpesvirus RTA locus in the context of the viral genome. J Virol. 2009 Feb; 83(4):1811-22. Arumugaswami V, Sitapara R, Hwang S, Song MJ, Ho TN, Su NQ, Sue EY, Kanagavel V, Xing F, Zhang X, Zhao M, Deng H, Wu TT, Kanagavel S, Zhang L, Dandekar S, Papp J, Sun R. PMID: 19073723; PMCID: PMC2643748.
      View in: PubMed   Mentions: 5     Fields:    Translation:AnimalsCells
    94. High-resolution functional profiling of hepatitis C virus genome. PLoS Pathog. 2008 Oct; 4(10):e1000182. Arumugaswami V, Remenyi R, Kanagavel V, Sue EY, Ngoc Ho T, Liu C, Fontanes V, Dasgupta A, Sun R. PMID: 18927624; PMCID: PMC2564836.
      View in: PubMed   Mentions: 39     Fields:    Translation:Cells
    95. A repetitive region of gammaherpesvirus genomic DNA is a ligand for induction of type I interferon. J Virol. 2008 Mar; 82(5):2208-17. Sanchez DJ, Miranda D, Arumugaswami V, Hwang S, Singer AE, Senaati A, Shahangian A, Song MJ, Sun R, Cheng G. PMID: 18077715; PMCID: PMC2258961.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansAnimalsCells
    96. ORF18 is a transfactor that is essential for late gene transcription of a gammaherpesvirus. J Virol. 2006 Oct; 80(19):9730-40. Arumugaswami V, Wu TT, Martinez-Guzman D, Jia Q, Deng H, Reyes N, Sun R. PMID: 16973577; PMCID: PMC1617240.
      View in: PubMed   Mentions: 40     Fields:    Translation:HumansAnimalsCells
    97. Examination of the effect of a naturally occurring mutation in glycoprotein L on Marek's disease virus pathogenesis. Avian Dis. 2006 Mar; 50(1):96-103. Santin ER, Shamblin CE, Prigge JT, Arumugaswami V, Dienglewicz RL, Parcells MS. PMID: 16617990.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    98. Nuclear localization and dynamic properties of the Marek's disease virus oncogene products Meq and Meq/vIL8. J Virol. 2006 Feb; 80(3):1160-6. Anobile JM, Arumugaswami V, Downs D, Czymmek K, Parcells M, Schmidt CJ. PMID: 16414993; PMCID: PMC1346918.
      View in: PubMed   Mentions: 10     Fields:    Translation:AnimalsCells
    99. Comparative analysis of Marek's disease virus (MDV) glycoprotein-, lytic antigen pp38- and transformation antigen Meq-encoding genes: association of meq mutations with MDVs of high virulence. Vet Microbiol. 2004 Sep 08; 102(3-4):147-67. Shamblin CE, Greene N, Arumugaswami V, Dienglewicz RL, Parcells MS. PMID: 15327791.
      View in: PubMed   Mentions: 47     Fields:    Translation:AnimalsCells
    100. Marek's disease virus reactivation from latency: changes in gene expression at the origin of replication. Poult Sci. 2003 Jun; 82(6):893-8. Parcells MS, Arumugaswami V, Prigge JT, Pandya K, Dienglewicz RL. PMID: 12817443.
      View in: PubMed   Mentions: 16     Fields:    Translation:AnimalsCells
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