Loading...

Aldrovandi, Grace M

Title(s)Professor, Pediatrics
SchoolPed - Infectious Diseases
Phone3109833084
vCardDownload vCard

    Collapse Research 
    Collapse Research Activities and Funding
    Effects of Human Milk Oligosaccharides and Gut Microbiome on Growth and Morbidity in HIV-Exposed Uninfected Infants
    NIH/NICHD R01HD096999Apr 24, 2019 - Mar 31, 2024
    Role: Co-Principal Investigator
    Maturation, Infectibility, and Trauma(MIT) Contributes to HIV Susceptibility in Adolescents
    NIH/NIAID R01AI128796Feb 24, 2017 - Jan 31, 2021
    Role: Principal Investigator
    Laboratory Center, AIDS Clinical Trials Group (ACTG); LC 2 / 3
    NIH/NIAID UM1AI106701Jan 1, 2014 - Nov 30, 2020
    Role: Principal Investigator
    International Maternal Pediatric Adolescent AIDS Clinical Trials (IMPAACT) Laboratory Center
    NIH/NIAID UM1AI106716Jan 1, 2014 - Nov 30, 2020
    Role: Principal Investigator
    Oral Transmission of HIV through Breastfeeding
    NIH/NIDCR R01DE021238Sep 1, 2010 - May 31, 2014
    Role: Co-Principal Investigator
    Immunologic Effects of Lactation on HIV infected women
    NIH/NICHD R21HD049287Mar 1, 2005 - Feb 28, 2008
    Role: Principal Investigator
    Pathogenesis of Mother to Child Transmission of HIV
    NIH/NICHD R01HD040777Jul 5, 2002 - May 31, 2014
    Role: Principal Investigator
    HIV RESISTANCE AND RECOMBINATION IN SCID-HU MICE
    NIH/NIAID R01AI041924May 1, 1998 - Apr 30, 2003
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
    List All   |   Timeline
    1. Birse KD, Kratzer K, Zuend CF, Mutch S, Noël-Romas L, Lamont A, Abou M, Jalil E, Veloso V, Grinsztejn B, Friedman RK, Broliden K, Bradley F, Poliquin V, Li F, Yanavich C, Burgener A, Aldrovandi G. The neovaginal microbiome of transgender women post-gender reassignment surgery. Microbiome. 2020 May 05; 8(1):61. PMID: 32370783.
      View in: PubMed
    2. Contreras DA, Fitzwater SP, Nanayakkara DD, Schaenman J, Aldrovandi GM, Garner OB, Yang S. Coinfections of Two Strains of NDM-1- and OXA-232-Coproducing Klebsiella pneumoniae in a Kidney Transplant Patient. Antimicrob Agents Chemother. 2020 Mar 24; 64(4). PMID: 31527031.
      View in: PubMed
    3. Farr Zuend C, Tobin NH, Vera T, Kotyrba L, Noël-Romas L, Birse K, Mutch S, Li F, Lee D, McCorrister S, Westmacott G, Aldrovandi GM, Burgener A. Pregnancy associates with alterations to the host and microbial proteome in vaginal mucosa. Am J Reprod Immunol. 2020 Mar 20; e13235. PMID: 32196803.
      View in: PubMed
    4. Kordy K, Gaufin T, Mwangi M, Li F, Cerini C, Lee DJ, Adisetiyo H, Woodward C, Pannaraj PS, Tobin NH, Aldrovandi GM. Contributions to human breast milk microbiome and enteromammary transfer of Bifidobacterium breve. PLoS One. 2020; 15(1):e0219633. PMID: 31990909.
      View in: PubMed
    5. Kuhn L, Strehlau R, Shiau S, Patel F, Shen Y, Technau KG, Burke M, Sherman G, Coovadia A, Aldrovandi GM, Hazra R, Tsai WY, Tiemessen CT, Abrams EJ. Early antiretroviral treatment of infants to attain HIV remission. EClinicalMedicine. 2020 Jan; 18:100241. PMID: 31993578.
      View in: PubMed
    6. Joseph Davey DL, Pintye J, Baeten JM, Aldrovandi G, Baggaley R, Bekker LG, Celum C, Chi BH, Coates TJ, Haberer JE, Heffron R, Kinuthia J, Matthews LT, McIntyre J, Moodley D, Mofenson LM, Mugo N, Myer L, Mujugira A, Shoptaw S, Stranix-Chibanda L, John-Stewart G. Emerging evidence from a systematic review of safety of pre-exposure prophylaxis for pregnant and postpartum women: where are we now and where are we heading? J Int AIDS Soc. 2020 Jan; 23(1):e25426. PMID: 31912985.
      View in: PubMed
    7. Cook RR, Fulcher JA, Tobin NH, Li F, Lee D, Woodward C, Javanbakht M, Brookmeyer R, Shoptaw S, Bolan R, Aldrovandi GM, Gorbach PM. Combined effects of HIV and obesity on the gastrointestinal microbiome of young men who have sex with men. HIV Med. 2019 Dec 27. PMID: 31883184.
      View in: PubMed
    8. Bender JM, Li F, Purswani H, Capretz T, Cerini C, Zabih S, Hung L, Francis N, Chin S, Pannaraj PS, Aldrovandi G. Early exposure to antibiotics in the neonatal intensive care unit alters the taxonomic and functional infant gut microbiome. J Matern Fetal Neonatal Med. 2019 Nov 19; 1-9. PMID: 31744351.
      View in: PubMed
    9. Fulcher JA, Li F, Cook RR, Zabih S, Louie A, Okochi H, Tobin NH, Gandhi M, Shoptaw S, Gorbach PM, Aldrovandi GM. Rectal Microbiome Alterations Associated With Oral Human Immunodeficiency Virus Pre-Exposure Prophylaxis. Open Forum Infect Dis. 2019 Nov; 6(11):ofz463. PMID: 32258202.
      View in: PubMed
    10. Cook RR, Fulcher JA, Tobin NH, Li F, Lee DJ, Woodward C, Javanbakht M, Brookmeyer R, Shoptaw S, Bolan R, Aldrovandi GM, Gorbach PM. Alterations to the Gastrointestinal Microbiome Associated with Methamphetamine Use among Young Men who have Sex with Men. Sci Rep. 2019 Oct 16; 9(1):14840. PMID: 31619731.
      View in: PubMed
    11. Kim-Chang JJ, Wilson L, Chan C, Fischer B, Venturi G, Goodenow MM, Aldrovandi G, Weber TJ, Sleasman JW. Tenofovir Has Minimal Effect on Biomarkers of Bone Health in Youth with HIV Receiving Initial Antiretroviral Therapy. AIDS Res Hum Retroviruses. 2019 08; 35(8):746-754. PMID: 31115244.
      View in: PubMed
    12. Cook RR, Fulcher JA, Tobin NH, Li F, Lee D, Javanbakht M, Brookmeyer R, Shoptaw S, Bolan R, Aldrovandi GM, Gorbach PM. Effects of HIV viremia on the gastrointestinal microbiome of young MSM. AIDS. 2019 04 01; 33(5):793-804. PMID: 30649052.
      View in: PubMed
    13. Patel K, Lindsey J, Angelidou K, Aldrovandi G, Palumbo P. Metabolic effects of initiating lopinavir/ritonavir-based regimens among young children. AIDS. 2018 10 23; 32(16):2327-2336. PMID: 30102656.
      View in: PubMed
    14. Ho NT, Li F, Lee-Sarwar KA, Tun HM, Brown BP, Pannaraj PS, Bender JM, Azad MB, Thompson AL, Weiss ST, Azcarate-Peril MA, Litonjua AA, Kozyrskyj AL, Jaspan HB, Aldrovandi GM, Kuhn L. Meta-analysis of effects of exclusive breastfeeding on infant gut microbiota across populations. Nat Commun. 2018 10 09; 9(1):4169. PMID: 30301893.
      View in: PubMed
    15. Fulcher JA, Hussain SK, Cook R, Li F, Tobin NH, Ragsdale A, Shoptaw S, Gorbach PM, Aldrovandi GM. Effects of Substance Use and Sex Practices on the Intestinal Microbiome During HIV-1 Infection. J Infect Dis. 2018 10 05; 218(10):1560-1570. PMID: 29982500.
      View in: PubMed
    16. Bender JM, Li F, Adisetiyo H, Lee D, Zabih S, Hung L, Wilkinson TA, Pannaraj PS, She RC, Bard JD, Tobin NH, Aldrovandi GM. Quantification of variation and the impact of biomass in targeted 16S rRNA gene sequencing studies. Microbiome. 2018 09 10; 6(1):155. PMID: 30201048.
      View in: PubMed
    17. Kordy K, Romeo AC, Lee DJ, Li F, Zabih S, Saavedra M, Cunningham NJ, Tobin N, Aldrovandi GM. Combination Antibiotics Improves Disease Activity and Alters Microbial Communities in Children With Ulcerative Colitis. J Pediatr Gastroenterol Nutr. 2018 09; 67(3):e60-e63. PMID: 29762192.
      View in: PubMed
    18. Pannaraj PS, Ly M, Cerini C, Saavedra M, Aldrovandi GM, Saboory AA, Johnson KM, Pride DT. Shared and Distinct Features of Human Milk and Infant Stool Viromes. Front Microbiol. 2018; 9:1162. PMID: 29910789.
      View in: PubMed
    19. Tobin NH, Woodward C, Zabih S, Lee DJ, Li F, Aldrovandi GM. A Method for Targeted 16S Sequencing of Human Milk Samples. J Vis Exp. 2018 03 23; (133). PMID: 29630048.
      View in: PubMed
    20. Gaufin T, Tobin NH, Aldrovandi GM. The importance of the microbiome in pediatrics and pediatric infectious diseases. Curr Opin Pediatr. 2018 02; 30(1):117-124. PMID: 29206649.
      View in: PubMed
    21. Lee HR, Li F, Choi UY, Yu HR, Aldrovandi GM, Feng P, Gao SJ, Hong YK, Jung JU. Deregulation of HDAC5 by Viral Interferon Regulatory Factor 3 Plays an Essential Role in Kaposi's Sarcoma-Associated Herpesvirus-Induced Lymphangiogenesis. mBio. 2018 01 16; 9(1). PMID: 29339432.
      View in: PubMed
    22. Jacobson DL, Lindsey JC, Coull BA, Mulligan K, Bhagwat P, Aldrovandi GM. The Association of Fat and Lean Tissue With Whole Body and Spine Bone Mineral Density Is Modified by HIV Status and Sex in Children and Youth. Pediatr Infect Dis J. 2018 Jan; 37(1):71-77. PMID: 28817419.
      View in: PubMed
    23. Mongkolrattanothai K, Naccache SN, Bender JM, Samayoa E, Pham E, Yu G, Dien Bard J, Miller S, Aldrovandi G, Chiu CY. Neurobrucellosis: Unexpected Answer From Metagenomic Next-Generation Sequencing. J Pediatric Infect Dis Soc. 2017 Nov 24; 6(4):393-398. PMID: 28062553.
      View in: PubMed
    24. Humphries RM, Yang S, Kim S, Muthusamy VR, Russell D, Trout AM, Zaroda T, Cheng QJ, Aldrovandi G, Uslan DZ, Hemarajata P, Rubin ZA. Duodenoscope-Related Outbreak of a Carbapenem-Resistant Klebsiella pneumoniae Identified Using Advanced Molecular Diagnostics. Clin Infect Dis. 2017 10 01; 65(7):1159-1166. PMID: 29579235.
      View in: PubMed
    25. Jean-Philippe P, Spiegel H, Gnanashanmugam D, Fitzgibbon J, D'Souza P, Crawford KW, Jayashankar L, Bacon MC, Essajee SM, Aldrovandi GM, Cotton M, Abrams EJ. HIV birth testing and linkage to care for HIV-infected infants. AIDS. 2017 08 24; 31(13):1797-1807. PMID: 28590330.
      View in: PubMed
    26. Pannaraj PS, Li F, Cerini C, Bender JM, Yang S, Rollie A, Adisetiyo H, Zabih S, Lincez PJ, Bittinger K, Bailey A, Bushman FD, Sleasman JW, Aldrovandi GM. Association Between Breast Milk Bacterial Communities and Establishment and Development of the Infant Gut Microbiome. JAMA Pediatr. 2017 07 01; 171(7):647-654. PMID: 28492938.
      View in: PubMed
    27. Yang S, Hemarajata P, Hindler J, Li F, Adisetiyo H, Aldrovandi G, Sebra R, Kasarskis A, MacCannell D, Didelot X, Russell D, Rubin Z, Humphries R. Evolution and Transmission of Carbapenem-Resistant Klebsiella pneumoniae Expressing the blaOXA-232 Gene During an Institutional Outbreak Associated With Endoscopic Retrograde Cholangiopancreatography. Clin Infect Dis. 2017 Apr 01; 64(7):894-901. PMID: 28362935.
      View in: PubMed
    28. Nakamura KJ, Heath L, Sobrera ER, Wilkinson TA, Semrau K, Kankasa C, Tobin NH, Webb NE, Lee B, Thea DM, Kuhn L, Mullins JI, Aldrovandi GM. Breast milk and in utero transmission of HIV-1 select for envelope variants with unique molecular signatures. Retrovirology. 2017 01 26; 14(1):6. PMID: 28122636.
      View in: PubMed
    29. Ruan A, Tobin NH, Mulligan K, Rollie A, Li F, Sleasman J, Aldrovandi GM. Brief Report: Macrophage Activation in HIV-Infected Adolescent Males Contributes to Differential Bone Loss by Sex: Adolescent Trials Network Study 021. J Acquir Immune Defic Syndr. 2016 08 01; 72(4):372-5. PMID: 26885808.
      View in: PubMed
    30. Bender JM, Li F, Martelly S, Byrt E, Rouzier V, Leo M, Tobin N, Pannaraj PS, Adisetiyo H, Rollie A, Santiskulvong C, Wang S, Autran C, Bode L, Fitzgerald D, Kuhn L, Aldrovandi GM. Maternal HIV infection influences the microbiome of HIV-uninfected infants. Sci Transl Med. 2016 07 27; 8(349):349ra100. PMID: 27464748.
      View in: PubMed
    31. Yang Y, He S, Wang Q, Li F, Kwak MJ, Chen S, O'Connell D, Zhang T, Pirooz SD, Jeon YH, Chimge NO, Frenkel B, Choi Y, Aldrovandi GM, Oh BH, Yuan Z, Liang C. Autophagic UVRAG Promotes UV-Induced Photolesion Repair by Activation of the CRL4(DDB2) E3 Ligase. Mol Cell. 2016 05 19; 62(4):507-19. PMID: 27203177.
      View in: PubMed
    32. Smit MA, Wang HL, Kim E, Barragan N, Aldrovandi GM, El Amin AN, Mascola L, Pannaraj PS. Influenza Vaccine is Protective Against Laboratory-confirmed Influenza in Obese Children. Pediatr Infect Dis J. 2016 Apr; 35(4):440-5. PMID: 26658380.
      View in: PubMed
    33. Yang S, Hemarajata P, Hindler J, Ward K, Adisetiyo H, Li F, Aldrovandi GM, Green NM, Russell D, Rubin Z, Humphries RM. Investigation of a suspected nosocomial transmission of blaKPC3-mediated carbapenem-resistant Klebsiella pneumoniae by whole genome sequencing. Diagn Microbiol Infect Dis. 2016 Apr; 84(4):337-42. PMID: 26867964.
      View in: PubMed
    34. Van Haren K, Ayscue P, Waubant E, Clayton A, Sheriff H, Yagi S, Glenn-Finer R, Padilla T, Strober JB, Aldrovandi G, Wadford DA, Chiu CY, Xia D, Harriman K, Watt JP, Glaser CA. Acute Flaccid Myelitis of Unknown Etiology in California, 2012-2015. JAMA. 2015 Dec 22-29; 314(24):2663-71. PMID: 26720027.
      View in: PubMed
    35. Wahl A, Baker C, Spagnuolo RA, Stamper LW, Fouda GG, Permar SR, Hinde K, Kuhn L, Bode L, Aldrovandi GM, Garcia JV. Breast Milk of HIV-Positive Mothers Has Potent and Species-Specific In Vivo HIV-Inhibitory Activity. J Virol. 2015 Nov; 89(21):10868-78. PMID: 26292320.
      View in: PubMed
    36. Lombardi F, Nakamura KJ, Chen T, Sobrera ER, Tobin NH, Aldrovandi GM. A Conserved Glycan in the C2 Domain of HIV-1 Envelope Acts as a Molecular Switch to Control X4 Utilization by Clonal Variants with Identical V3 Loops. PLoS One. 2015; 10(6):e0128116. PMID: 26083631.
      View in: PubMed
    37. Greninger AL, Naccache SN, Messacar K, Clayton A, Yu G, Somasekar S, Federman S, Stryke D, Anderson C, Yagi S, Messenger S, Wadford D, Xia D, Watt JP, Van Haren K, Dominguez SR, Glaser C, Aldrovandi G, Chiu CY. A novel outbreak enterovirus D68 strain associated with acute flaccid myelitis cases in the USA (2012-14): a retrospective cohort study. Lancet Infect Dis. 2015 Jun; 15(6):671-82. PMID: 25837569.
      View in: PubMed
    38. Sattler FR, He J, Letendre S, Wilson C, Sanders C, Heaton R, Ellis R, Franklin D, Aldrovandi G, Marra CM, Clifford D, Morgello S, Grant I, McCutchan JA. Abdominal obesity contributes to neurocognitive impairment in HIV-infected patients with increased inflammation and immune activation. J Acquir Immune Defic Syndr. 2015 Mar 01; 68(3):281-8. PMID: 25469522.
      View in: PubMed
    39. Kuhn L, Kim HY, Hsiao L, Nissan C, Kankasa C, Mwiya M, Thea DM, Aldrovandi GM, Bode L. Oligosaccharide composition of breast milk influences survival of uninfected children born to HIV-infected mothers in Lusaka, Zambia. J Nutr. 2015 Jan; 145(1):66-72. PMID: 25527660.
      View in: PubMed
    40. Rubinstein ML, Harris DR, Rudy BJ, Kapogiannis BG, Aldrovandi GM, Mulligan K. Exploration of the Effect of Tobacco Smoking on Metabolic Measures in Young People Living with HIV. AIDS Res Treat. 2014; 2014:740545. PMID: 25114801.
      View in: PubMed
    41. Pannaraj PS, Wang HL, Rivas H, Wiryawan H, Smit M, Green N, Aldrovandi GM, El Amin AN, Mascola L. School-located influenza vaccination decreases laboratory-confirmed influenza and improves school attendance. Clin Infect Dis. 2014 Aug 01; 59(3):325-32. PMID: 24829215.
      View in: PubMed
    42. Felsenstein S, Yang S, Eubanks N, Sobrera E, Grimm JP, Aldrovandi G. Human parechovirus central nervous system infections in southern California children. Pediatr Infect Dis J. 2014 Apr; 33(4):e87-91. PMID: 24104958.
      View in: PubMed
    43. Segat L, Zupin L, Kim HY, Catamo E, Thea DM, Kankasa C, Aldrovandi GM, Kuhn L, Crovella S. HLA-G 14?bp deletion/insertion polymorphism and mother-to-child transmission of HIV. Tissue Antigens. 2014 Mar; 83(3):161-7. PMID: 24571474.
      View in: PubMed
    44. Tobin NH, Aldrovandi GM. Are infants unique in their ability to be "functionally cured" of HIV-1? Curr HIV/AIDS Rep. 2014 Mar; 11(1):1-10. PMID: 24390641.
      View in: PubMed
    45. Chan CS, Kim HY, Autran C, Kim JH, Sinkala M, Kankasa C, Mwiya M, Thea DM, Aldrovandi GM, Kuhn L, Bode L. Human milk galectin-3 binding protein and breast-feeding-associated HIV transmission. Pediatr Infect Dis J. 2013 Dec; 32(12):e473-5. PMID: 23899964.
      View in: PubMed
    46. Sriaroon P, Elizalde A, Perez EE, Leiding JW, Aldrovandi GM, Sleasman JW. Psychrobacter immobilis septicemia in a boy with X-linked chronic granulomatous disease and fulminant hepatic failure. J Clin Immunol. 2014 Jan; 34(1):39-41. PMID: 24217814.
      View in: PubMed
    47. Timmons T, Shen C, Aldrovandi G, Rollie A, Gupta SK, Stein JH, Dubé MP. Microbial translocation and metabolic and body composition measures in treated and untreated HIV infection. AIDS Res Hum Retroviruses. 2014 Mar; 30(3):272-7. PMID: 24033288.
      View in: PubMed
    48. Tobin NH, Aldrovandi GM. Immunology of pediatric HIV infection. Immunol Rev. 2013 Jul; 254(1):143-69. PMID: 23772619.
      View in: PubMed
    49. Kuhn L, Kim HY, Walter J, Thea DM, Sinkala M, Mwiya M, Kankasa C, Decker D, Aldrovandi GM. HIV-1 concentrations in human breast milk before and after weaning. Sci Transl Med. 2013 Apr 17; 5(181):181ra51. PMID: 23596203.
      View in: PubMed
    50. Bonhoeffer J, Imoukhuede EB, Aldrovandi G, Bachtiar NS, Chan ES, Chang S, Chen RT, Fernandopulle R, Goldenthal KL, Heffelfinger JD, Hossain S, Jevaji I, Khamesipour A, Kochhar S, Makhene M, Malkin E, Nalin D, Prevots R, Ramasamy R, Sellers S, Vekemans J, Walker KB, Wilson P, Wong V, Zaman K, Heininger U. Template protocol for clinical trials investigating vaccines--focus on safety elements. Vaccine. 2013 Nov 12; 31(47):5602-20. PMID: 23499603.
      View in: PubMed
    51. Semrau K, Kuhn L, Brooks DR, Cabral H, Sinkala M, Kankasa C, Thea DM, Aldrovandi GM. Dynamics of breast milk HIV-1 RNA with unilateral mastitis or abscess. J Acquir Immune Defic Syndr. 2013 Mar 01; 62(3):348-55. PMID: 23202812.
      View in: PubMed
    52. Nakamura KJ, Cerini C, Sobrera ER, Heath L, Sinkala M, Kankasa C, Thea DM, Mullins JI, Kuhn L, Aldrovandi GM. Coverage of primary mother-to-child HIV transmission isolates by second-generation broadly neutralizing antibodies. AIDS. 2013 Jan 28; 27(3):337-46. PMID: 23296195.
      View in: PubMed
    53. Kim HY, Kasonde P, Mwiya M, Thea DM, Kankasa C, Sinkala M, Aldrovandi G, Kuhn L. Pregnancy loss and role of infant HIV status on perinatal mortality among HIV-infected women. BMC Pediatr. 2012 Aug 31; 12:138. PMID: 22937874.
      View in: PubMed
    54. Blodget E, Shen C, Aldrovandi G, Rollie A, Gupta SK, Stein JH, Dubé MP. Relationship between microbial translocation and endothelial function in HIV infected patients. PLoS One. 2012; 7(8):e42624. PMID: 22952600.
      View in: PubMed
    55. Bode L, Kuhn L, Kim HY, Hsiao L, Nissan C, Sinkala M, Kankasa C, Mwiya M, Thea DM, Aldrovandi GM. Human milk oligosaccharide concentration and risk of postnatal transmission of HIV through breastfeeding. Am J Clin Nutr. 2012 Oct; 96(4):831-9. PMID: 22894939.
      View in: PubMed
    56. Henrick BM, Nag K, Yao XD, Drannik AG, Aldrovandi GM, Rosenthal KL. Milk matters: soluble Toll-like receptor 2 (sTLR2) in breast milk significantly inhibits HIV-1 infection and inflammation. PLoS One. 2012; 7(7):e40138. PMID: 22792230.
      View in: PubMed
    57. Ponrartana S, Aggabao PC, Hu HH, Aldrovandi GM, Wren TA, Gilsanz V. Brown adipose tissue and its relationship to bone structure in pediatric patients. J Clin Endocrinol Metab. 2012 Aug; 97(8):2693-8. PMID: 22593587.
      View in: PubMed
    58. Mulligan K, Harris DR, Emmanuel P, Fielding RA, Worrell C, Kapogiannis BG, Monte D, Sleasman J, Wilson CM, Aldrovandi GM. Low bone mass in behaviorally HIV-infected young men on antiretroviral therapy: Adolescent Trials Network Study 021B. Clin Infect Dis. 2012 Aug; 55(3):461-8. PMID: 22573848.
      View in: PubMed
    59. Lindsey JC, Jacobson DL, Li H, Houseman EA, Aldrovandi GM, Mulligan K. Using cluster heat maps to investigate relationships between body composition and laboratory measurements in HIV-infected and HIV-uninfected children and young adults. J Acquir Immune Defic Syndr. 2012 Mar 01; 59(3):325-8. PMID: 22083069.
      View in: PubMed
    60. Fiscus SA, Aldrovandi GM. Virologic determinants of breast milk transmission of HIV-1. Adv Exp Med Biol. 2012; 743:69-80. PMID: 22454342.
      View in: PubMed
    61. Kuhn L, Aldrovandi G. Pendulum swings in HIV-1 and infant feeding policies: now halfway back. Adv Exp Med Biol. 2012; 743:273-87. PMID: 22454357.
      View in: PubMed
    62. Krogstad P, Aldrovandi G. Editorial: developmental regulation of P-glycoprotein and HIV therapy: spare the thymus but spoil the child? J Leukoc Biol. 2011 Oct; 90(4):639-41. PMID: 21965311.
      View in: PubMed
    63. Walter J, Fraga L, Orin MJ, Decker WD, Gipps T, Stek A, Aldrovandi GM. Immunomodulatory factors in cervicovaginal secretions from pregnant and non-pregnant women: a cross-sectional study. BMC Infect Dis. 2011 Sep 30; 11:263. PMID: 21961998.
      View in: PubMed
    64. Kiser JJ, Rutstein RM, Samson P, Graham B, Aldrovandi G, Mofenson LM, Smith E, Schnittman S, Fenton T, Brundage RC, Fletcher CV. Atazanavir and atazanavir/ritonavir pharmacokinetics in HIV-infected infants, children, and adolescents. AIDS. 2011 Jul 31; 25(12):1489-96. PMID: 21610486.
      View in: PubMed
    65. Semrau K, Kuhn L, Brooks DR, Cabral H, Sinkala M, Kankasa C, Thea DM, Aldrovandi GM. Exclusive breastfeeding, maternal HIV disease, and the risk of clinical breast pathology in HIV-infected, breastfeeding women. Am J Obstet Gynecol. 2011 Oct; 205(4):344.e1-8. PMID: 21784403.
      View in: PubMed
    66. Fawzy A, Arpadi S, Kankasa C, Sinkala M, Mwiya M, Thea DM, Aldrovandi GM, Kuhn L. Early weaning increases diarrhea morbidity and mortality among uninfected children born to HIV-infected mothers in Zambia. J Infect Dis. 2011 May 01; 203(9):1222-30. PMID: 21459815.
      View in: PubMed
    67. Jassal MS, Aldrovandi GM. 2050: Ending the odyssey of the great white plague. Part of a series on Pediatric Pharmacology, guest edited by Gianvincenzo Zuccotti, Emilio Clementi, and Massimo Molteni. Pharmacol Res. 2011 Sep; 64(3):176-9. PMID: 21540112.
      View in: PubMed
    68. Gray RR, Salemi M, Lowe A, Nakamura KJ, Decker WD, Sinkala M, Kankasa C, Mulligan CJ, Thea DM, Kuhn L, Aldrovandi G, Goodenow MM. Multiple independent lineages of HIV-1 persist in breast milk and plasma. AIDS. 2011 Jan 14; 25(2):143-52. PMID: 21173592.
      View in: PubMed
    69. Kuhn L, Aldrovandi G. Survival and health benefits of breastfeeding versus artificial feeding in infants of HIV-infected women: developing versus developed world. Clin Perinatol. 2010 Dec; 37(4):843-62, x. PMID: 21078454.
      View in: PubMed
    70. Aldrovandi GM, Kuhn L. What infants and breasts can teach us about natural protection from HIV infection. J Infect Dis. 2010 Nov 01; 202 Suppl 3:S366-70. PMID: 20887226.
      View in: PubMed
    71. McComsey GA, Tebas P, Shane E, Yin MT, Overton ET, Huang JS, Aldrovandi GM, Cardoso SW, Santana JL, Brown TT. Bone disease in HIV infection: a practical review and recommendations for HIV care providers. Clin Infect Dis. 2010 Oct 15; 51(8):937-46. PMID: 20839968.
      View in: PubMed
    72. Kuhn L, Aldrovandi GM, Sinkala M, Kankasa C, Mwiya M, Thea DM. Potential impact of new WHO criteria for antiretroviral treatment for prevention of mother-to- child HIV transmission. AIDS. 2010 Jun 01; 24(9):1374-7. PMID: 20568677.
      View in: PubMed
    73. Murnane PM, Arpadi SM, Sinkala M, Kankasa C, Mwiya M, Kasonde P, Thea DM, Aldrovandi GM, Kuhn L. Lactation-associated postpartum weight changes among HIV-infected women in Zambia. Int J Epidemiol. 2010 Oct; 39(5):1299-310. PMID: 20484334.
      View in: PubMed
    74. Heath L, Conway S, Jones L, Semrau K, Nakamura K, Walter J, Decker WD, Hong J, Chen T, Heil M, Sinkala M, Kankasa C, Thea DM, Kuhn L, Mullins JI, Aldrovandi GM. Restriction of HIV-1 genotypes in breast milk does not account for the population transmission genetic bottleneck that occurs following transmission. PLoS One. 2010 Apr 20; 5(4):e10213. PMID: 20422033.
      View in: PubMed
    75. Nakamura KJ, Gach JS, Jones L, Semrau K, Walter J, Bibollet-Ruche F, Decker JM, Heath L, Decker WD, Sinkala M, Kankasa C, Thea D, Mullins J, Kuhn L, Zwick MB, Aldrovandi GM. 4E10-resistant HIV-1 isolated from four subjects with rare membrane-proximal external region polymorphisms. PLoS One. 2010 Mar 23; 5(3):e9786. PMID: 20352106.
      View in: PubMed
    76. Jacobson DL, Lindsey JC, Gordon CM, Moye J, Hardin DS, Mulligan K, Aldrovandi GM. Total body and spinal bone mineral density across Tanner stage in perinatally HIV-infected and uninfected children and youth in PACTG 1045. AIDS. 2010 Mar 13; 24(5):687-96. PMID: 20168204.
      View in: PubMed
    77. Kuhn L, Sinkala M, Semrau K, Kankasa C, Kasonde P, Mwiya M, Hu CC, Tsai WY, Thea DM, Aldrovandi GM. Elevations in mortality associated with weaning persist into the second year of life among uninfected children born to HIV-infected mothers. Clin Infect Dis. 2010 Feb 01; 50(3):437-44. PMID: 20047479.
      View in: PubMed
    78. Mulligan K, Harris DR, Monte D, Stoszek S, Emmanuel P, Hardin DS, Kapogiannis BG, Worrell C, Meyer WA, Sleasman J, Wilson CM, Aldrovandi GM. Obesity and dyslipidemia in behaviorally HIV-infected young women: Adolescent Trials Network study 021. Clin Infect Dis. 2010 Jan 01; 50(1):106-14. PMID: 19947855.
      View in: PubMed
    79. Kuhn L, Sinkala M, Thea DM, Kankasa C, Aldrovandi GM. HIV prevention is not enough: child survival in the context of prevention of mother to child HIV transmission. J Int AIDS Soc. 2009 Dec 11; 12:36. PMID: 20015345.
      View in: PubMed
    80. Aldrovandi GM, Chu C, Shearer WT, Li D, Walter J, Thompson B, McIntosh K, Foca M, Meyer WA, Ha BF, Rich KC, Moye J. Antiretroviral exposure and lymphocyte mtDNA content among uninfected infants of HIV-1-infected women. Pediatrics. 2009 Dec; 124(6):e1189-97. PMID: 19933732.
      View in: PubMed
    81. Walter J, Ghosh MK, Kuhn L, Semrau K, Sinkala M, Kankasa C, Thea DM, Aldrovandi GM. High concentrations of interleukin 15 in breast milk are associated with protection against postnatal HIV transmission. J Infect Dis. 2009 Nov 15; 200(10):1498-502. PMID: 19835475.
      View in: PubMed
    82. Chi BH, Ellis GM, Chintu N, Cantrell RA, Sinkala M, Aldrovandi GM, Warrier R, Mbewe F, Nakamura K, Stringer EM, Frenkel LM, Stringer JS. Intrapartum tenofovir and emtricitabine reduces low-concentration drug resistance selected by single-dose nevirapine for perinatal HIV prevention. AIDS Res Hum Retroviruses. 2009 Nov; 25(11):1099-106. PMID: 19886836.
      View in: PubMed
    83. Kuhn L, Aldrovandi GM. Clean water helps but is not enough: challenges for safe replacement feeding of infants exposed to HIV. J Infect Dis. 2009 Oct 15; 200(8):1183-5. PMID: 19758096.
      View in: PubMed
    84. Kuhn L, Semrau K, Ramachandran S, Sinkala M, Scott N, Kasonde P, Mwiya M, Kankasa C, Decker D, Thea DM, Aldrovandi GM. Mortality and virologic outcomes after access to antiretroviral therapy among a cohort of HIV-infected women who received single-dose nevirapine in Lusaka, Zambia. J Acquir Immune Defic Syndr. 2009 Sep 01; 52(1):132-6. PMID: 19506483.
      View in: PubMed
    85. Walter J, Kuhn L, Semrau K, Decker DW, Sinkala M, Kankasa C, Thea DM, Bulterys M, Ou CY, Aldrovandi GM. Detection of low levels of human immunodeficiency virus (HIV) may be critical for early diagnosis of pediatric HIV infection by use of dried blood spots. J Clin Microbiol. 2009 Sep; 47(9):2989-91. PMID: 19625479.
      View in: PubMed
    86. Kuhn L, Aldrovandi GM, Sinkala M, Kankasa C, Semrau K, Kasonde P, Mwiya M, Tsai WY, Thea DM. Differential effects of early weaning for HIV-free survival of children born to HIV-infected mothers by severity of maternal disease. PLoS One. 2009 Jun 26; 4(6):e6059. PMID: 19557167.
      View in: PubMed
    87. Arpadi S, Fawzy A, Aldrovandi GM, Kankasa C, Sinkala M, Mwiya M, Thea DM, Kuhn L. Growth faltering due to breastfeeding cessation in uninfected children born to HIV-infected mothers in Zambia. Am J Clin Nutr. 2009 Aug; 90(2):344-53. PMID: 19553300.
      View in: PubMed
    88. Aldrovandi GM, Lindsey JC, Jacobson DL, Zadzilka A, Sheeran E, Moye J, Borum P, Meyer WA, Hardin DS, Mulligan K. Morphologic and metabolic abnormalities in vertically HIV-infected children and youth. AIDS. 2009 Mar 27; 23(6):661-72. PMID: 19279441.
      View in: PubMed
    89. Walter J, Kuhn L, Kankasa C, Semrau K, Sinkala M, Thea DM, Aldrovandi GM. Reuse of single-dose nevirapine in subsequent pregnancies for the prevention of mother-to-child HIV transmission in Lusaka, Zambia: a cohort study. BMC Infect Dis. 2008 Dec 30; 8:172. PMID: 19116004.
      View in: PubMed
    90. Fox MP, Brooks DR, Kuhn L, Aldrovandi G, Sinkala M, Kankasa C, Horsburgh R, Thea DM. Role of breastfeeding cessation in mediating the relationship between maternal HIV disease stage and increased child mortality among HIV-exposed uninfected children. Int J Epidemiol. 2009 Apr; 38(2):569-76. PMID: 19047077.
      View in: PubMed
    91. Chen TK, Aldrovandi GM. Review of HIV antiretroviral drug resistance. Pediatr Infect Dis J. 2008 Aug; 27(8):749-52. PMID: 18664987.
      View in: PubMed
    92. Robbins BL, Capparelli EV, Chadwick EG, Yogev R, Serchuck L, Worrell C, Smith ME, Alvero C, Fenton T, Heckman B, Pelton SI, Aldrovandi G, Borkowsky W, Rodman J, Havens PL. Pharmacokinetics of high-dose lopinavir-ritonavir with and without saquinavir or nonnucleoside reverse transcriptase inhibitors in human immunodeficiency virus-infected pediatric and adolescent patients previously treated with protease inhibitors. Antimicrob Agents Chemother. 2008 Sep; 52(9):3276-83. PMID: 18625762.
      View in: PubMed
    93. Mitchell C, Jennings C, Brambilla D, Aldrovandi G, Amedee AM, Beck I, Bremer JW, Coombs R, Decker D, Fiscus S, Fitzgibbon J, Luzuriaga K, Moye J, Palumbo P, Reichelderfer P, Somasundaran M, Stevens W, Frenkel L. Diminished human immunodeficiency virus type 1 DNA yield from dried blood spots after storage in a humid incubator at 37 degrees C compared to -20 degrees C. J Clin Microbiol. 2008 Sep; 46(9):2945-9. PMID: 18614660.
      View in: PubMed
    94. Kuhn L, Aldrovandi GM, Sinkala M, Kankasa C, Semrau K, Mwiya M, Kasonde P, Scott N, Vwalika C, Walter J, Bulterys M, Tsai WY, Thea DM. Effects of early, abrupt weaning on HIV-free survival of children in Zambia. N Engl J Med. 2008 Jul 10; 359(2):130-41. PMID: 18525036.
      View in: PubMed
    95. Fox MP, Brooks D, Kuhn L, Aldrovandi G, Sinkala M, Kankasa C, Mwiya M, Horsburgh R, Thea DM. Reduced mortality associated with breast-feeding-acquired HIV infection and breast-feeding among HIV-infected children in Zambia. J Acquir Immune Defic Syndr. 2008 May 01; 48(1):90-6. PMID: 18344878.
      View in: PubMed
    96. Semrau K, Ghosh M, Kankasa C, Sinkala M, Kasonde P, Mwiya M, Thea DM, Kuhn L, Aldrovandi GM. Temporal and lateral dynamics of HIV shedding and elevated sodium in breast milk among HIV-positive mothers during the first 4 months of breast-feeding. J Acquir Immune Defic Syndr. 2008 Mar 01; 47(3):320-8. PMID: 18398972.
      View in: PubMed
    97. Walter J, Kuhn L, Aldrovandi GM. Advances in basic science understanding of mother-to-child HIV-1 transmission. Curr Opin HIV AIDS. 2008 Mar; 3(2):146-50. PMID: 19372957.
      View in: PubMed
    98. Kuhn L, Sinkala M, Kankasa C, Semrau K, Kasonde P, Scott N, Mwiya M, Vwalika C, Walter J, Tsai WY, Aldrovandi GM, Thea DM. High uptake of exclusive breastfeeding and reduced early post-natal HIV transmission. PLoS One. 2007 Dec 26; 2(12):e1363. PMID: 18159246.
      View in: PubMed
    99. Kuhn L, Thea DM, Aldrovandi GM. Bystander effects: children who escape infection but not harm. J Acquir Immune Defic Syndr. 2007 Dec 15; 46(5):517-8. PMID: 18043311.
      View in: PubMed
    100. Chi BH, Sinkala M, Mbewe F, Cantrell RA, Kruse G, Chintu N, Aldrovandi GM, Stringer EM, Kankasa C, Safrit JT, Stringer JS. Single-dose tenofovir and emtricitabine for reduction of viral resistance to non-nucleoside reverse transcriptase inhibitor drugs in women given intrapartum nevirapine for perinatal HIV prevention: an open-label randomised trial. Lancet. 2007 Nov 17; 370(9600):1698-705. PMID: 17997151.
      View in: PubMed
    101. Castelletti E, Lo Caputo S, Kuhn L, Borelli M, Gajardo J, Sinkala M, Trabattoni D, Kankasa C, Lauri E, Clivio A, Piacentini L, Bray DH, Aldrovandi GM, Thea DM, Veas F, Nebuloni M, Mazzotta F, Clerici M. The mucosae-associated epithelial chemokine (MEC/CCL28) modulates immunity in HIV infection. PLoS One. 2007 Oct 03; 2(10):e969. PMID: 17912348.
      View in: PubMed
    102. Walter J, Kuhn L, Ghosh MK, Kankasa C, Semrau K, Sinkala M, Mwiya M, Thea DM, Aldrovandi GM. Low and undetectable breast milk interleukin-7 concentrations are associated with reduced risk of postnatal HIV transmission. J Acquir Immune Defic Syndr. 2007 Oct 01; 46(2):200-7. PMID: 17667336.
      View in: PubMed
    103. Dorosko SM, Thea DM, Saperstein G, Russell RM, Paape MJ, Hinckley LS, Decker WD, Semrau K, Sinkala M, Kasonde P, Kankasa C, Aldrovandi GM, Hamer DH. Veterinary field test as screening tool for mastitis and HIV-1 viral load in breastmilk from HIV-infected Zambian women. Breastfeed Med. 2007 Sep; 2(3):172-5. PMID: 17903106.
      View in: PubMed
    104. Bennetto-Hood C, Aldrovandi GM, King JR, Woodman K, Ashouri N, Acosta EP. Persistence of nevirapine in breast milk after discontinuation of treatment. Clin Infect Dis. 2007 Aug 01; 45(3):391-4. PMID: 17599320.
      View in: PubMed
    105. Kuhn L, Thea DM, Aldrovandi GM. Re: HIV-1 disease progression in breast-feeding and formula-feeding mothers: a prospective 2-year comparison of T cell subsets, HIV-1 RNA levels, and mortality. J Infect Dis. 2007 Jun 01; 195(11):1728-9; author reply 1729-30. PMID: 17471447.
      View in: PubMed
    106. Kuhn L, Trabattoni D, Kankasa C, Sinkala M, Lissoni F, Ghosh M, Aldrovandi G, Thea D, Clerici M. Hiv-specific secretory IgA in breast milk of HIV-positive mothers is not associated with protection against HIV transmission among breast-fed infants. J Pediatr. 2006 Nov; 149(5):611-6. PMID: 17095329.
      View in: PubMed
    107. Viani RM, Peralta L, Aldrovandi G, Kapogiannis BG, Mitchell R, Spector SA, Lie YS, Weidler JM, Bates MP, Liu N, Wilson CM. Prevalence of primary HIV-1 drug resistance among recently infected adolescents: a multicenter adolescent medicine trials network for HIV/AIDS interventions study. J Infect Dis. 2006 Dec 01; 194(11):1505-9. PMID: 17083034.
      View in: PubMed
    108. Walter J, Mwiya M, Scott N, Kasonde P, Sinkala M, Kankasa C, Kauchali S, Aldrovandi GM, Thea DM, Kuhn L. Reduction in preterm delivery and neonatal mortality after the introduction of antenatal cotrimoxazole prophylaxis among HIV-infected women with low CD4 cell counts. J Infect Dis. 2006 Dec 01; 194(11):1510-8. PMID: 17083035.
      View in: PubMed
    109. Murray LK, Haworth A, Semrau K, Singh M, Aldrovandi GM, Sinkala M, Thea DM, Bolton PA. Violence and abuse among HIV-infected women and their children in Zambia: a qualitative study. J Nerv Ment Dis. 2006 Aug; 194(8):610-5. PMID: 16909070.
      View in: PubMed
    110. Thea DM, Aldrovandi G, Kankasa C, Kasonde P, Decker WD, Semrau K, Sinkala M, Kuhn L. Post-weaning breast milk HIV-1 viral load, blood prolactin levels and breast milk volume. AIDS. 2006 Jul 13; 20(11):1539-47. PMID: 16847409.
      View in: PubMed
    111. Halvas EK, Aldrovandi GM, Balfe P, Beck IA, Boltz VF, Coffin JM, Frenkel LM, Hazelwood JD, Johnson VA, Kearney M, Kovacs A, Kuritzkes DR, Metzner KJ, Nissley DV, Nowicki M, Palmer S, Ziermann R, Zhao RY, Jennings CL, Bremer J, Brambilla D, Mellors JW. Blinded, multicenter comparison of methods to detect a drug-resistant mutant of human immunodeficiency virus type 1 at low frequency. J Clin Microbiol. 2006 Jul; 44(7):2612-4. PMID: 16825395.
      View in: PubMed
    112. Kuhn L, Sinkala M, Kankasa MP, Kasonde P, Thea DM, Aldrovandi GM. Nevirapine resistance viral mutations after repeat use of nevirapine for prevention of perinatal HIV transmission. J Acquir Immune Defic Syndr. 2006 Jun; 42(2):260-2. PMID: 16760802.
      View in: PubMed
    113. Semrau K, Kuhn L, Kasonde P, Sinkala M, Kankasa C, Shutes E, Vwalika C, Ghosh M, Aldrovandi G, Thea DM. Impact of chloroquine on viral load in breast milk. Trop Med Int Health. 2006 Jun; 11(6):800-3. PMID: 16772000.
      View in: PubMed
    114. Stephensen CB, Marquis GS, Kruzich LA, Douglas SD, Aldrovandi GM, Wilson CM. Vitamin D status in adolescents and young adults with HIV infection. Am J Clin Nutr. 2006 May; 83(5):1135-41. PMID: 16685057.
      View in: PubMed
    115. Albrecht S, Semrau K, Kasonde P, Sinkala M, Kankasa C, Vwalika C, Aldrovandi GM, Thea DM, Kuhn L. Predictors of nonadherence to single-dose nevirapine therapy for the prevention of mother-to-child HIV transmission. J Acquir Immune Defic Syndr. 2006 Jan 01; 41(1):114-8. PMID: 16340483.
      View in: PubMed
    116. Kuhn L, Kasonde P, Sinkala M, Kankasa C, Semrau K, Scott N, Tsai WY, Vermund SH, Aldrovandi GM, Thea DM. Does severity of HIV disease in HIV-infected mothers affect mortality and morbidity among their uninfected infants? Clin Infect Dis. 2005 Dec 01; 41(11):1654-61. PMID: 16267740.
      View in: PubMed
    117. Kuhn L, Kasonde P, Sinkala M, Kankasa C, Semrau K, Vwalika C, Tsai WY, Aldrovandi GM, Thea DM. Prolonged breast-feeding and mortality up to two years post-partum among HIV-positive women in Zambia. AIDS. 2005 Oct 14; 19(15):1677-81. PMID: 16184038.
      View in: PubMed
    118. King JR, Nachman S, Yogev R, Hodge J, Aldrovandi G, Hughes MD, Chen J, Wiznia A, Damle B, Acosta EP. Efficacy, tolerability and pharmacokinetics of two nelfinavir-based regimens in human immunodeficiency virus-infected children and adolescents: pediatric AIDS clinical trials group protocol 403. Pediatr Infect Dis J. 2005 Oct; 24(10):880-5. PMID: 16220085.
      View in: PubMed
    119. Huang DD, Bremer JW, Brambilla DJ, Palumbo PE, Aldrovandi G, Eshleman S, Brown C, Fiscus S, Frenkel L, Hamdan H, Hart S, Kovacs A, Krogstad P, LaRussa P, Sullivan J, Weinberg A, Zhao YQ. Model for assessment of proficiency of human immunodeficiency virus type 1 sequencing-based genotypic antiretroviral assays. J Clin Microbiol. 2005 Aug; 43(8):3963-70. PMID: 16081937.
      View in: PubMed
    120. Kuhn L, Trabattoni D, Kankasa C, Semrau K, Kasonde P, Lissoni F, Sinkala M, Ghosh M, Vwalika C, Aldrovandi GM, Thea DM, Clerici M. Alpha-defensins in the prevention of HIV transmission among breastfed infants. J Acquir Immune Defic Syndr. 2005 Jun 01; 39(2):138-42. PMID: 15905728.
      View in: PubMed
    121. Semrau K, Kuhn L, Vwalika C, Kasonde P, Sinkala M, Kankasa C, Shutes E, Aldrovandi G, Thea DM. Women in couples antenatal HIV counseling and testing are not more likely to report adverse social events. AIDS. 2005 Mar 24; 19(6):603-9. PMID: 15802979.
      View in: PubMed
    122. Sabbaj S, Ghosh MK, Edwards BH, Leeth R, Decker WD, Goepfert PA, Aldrovandi GM. Breast milk-derived antigen-specific CD8+ T cells: an extralymphoid effector memory cell population in humans. J Immunol. 2005 Mar 01; 174(5):2951-6. PMID: 15728507.
      View in: PubMed
    123. Bansal A, Gough E, Sabbaj S, Ritter D, Yusim K, Sfakianos G, Aldrovandi G, Kaslow RA, Wilson CM, Mulligan MJ, Kilby JM, Goepfert PA. CD8 T-cell responses in early HIV-1 infection are skewed towards high entropy peptides. AIDS. 2005 Feb 18; 19(3):241-50. PMID: 15718834.
      View in: PubMed
    124. Viganò A, Aldrovandi GM, Giacomet V, Merlo M, Martelli L, Beretta S, Luraschi P, Rombolà G, Mora S. Improvement in dyslipidaemia after switching stavudine to tenofovir and replacing protease inhibitors with efavirenz in HIV-infected children. Antivir Ther. 2005; 10(8):917-24. PMID: 16430197.
      View in: PubMed
    125. King JR, Yogev R, Aldrovandi G, Chadwick E, Acosta EP. Pharmacokinetics of antiretrovirals administered to HIV-infected children via gastrostomy tube. HIV Clin Trials. 2004 Sep-Oct; 5(5):288-93. PMID: 15562369.
      View in: PubMed
    126. Thea DM, Vwalika C, Kasonde P, Kankasa C, Sinkala M, Semrau K, Shutes E, Ayash C, Tsai WY, Aldrovandi G, Kuhn L. Issues in the design of a clinical trial with a behavioral intervention--the Zambia exclusive breast-feeding study. Control Clin Trials. 2004 Aug; 25(4):353-65. PMID: 15296810.
      View in: PubMed
    127. Stringer JS, Sinkala M, Goldenberg RL, Kumwenda R, Acosta EP, Aldrovandi GM, Stout JP, Vermund SH. Universal nevirapine upon presentation in labor to prevent mother-to-child HIV transmission in high prevalence settings. AIDS. 2004 Apr 09; 18(6):939-43. PMID: 15060442.
      View in: PubMed
    128. Levy DN, Aldrovandi GM, Kutsch O, Shaw GM. Dynamics of HIV-1 recombination in its natural target cells. Proc Natl Acad Sci U S A. 2004 Mar 23; 101(12):4204-9. PMID: 15010526.
      View in: PubMed
    129. Tang J, Tang S, Lobashevsky E, Zulu I, Aldrovandi G, Allen S, Kaslow RA. HLA allele sharing and HIV type 1 viremia in seroconverting Zambians with known transmitting partners. AIDS Res Hum Retroviruses. 2004 Jan; 20(1):19-25. PMID: 15000695.
      View in: PubMed
    130. Stringer JS, Sinkala M, Chapman V, Acosta EP, Aldrovandi GM, Mudenda V, Stout JP, Goldenberg RL, Kumwenda R, Vermund SH. Timing of the maternal drug dose and risk of perinatal HIV transmission in the setting of intrapartum and neonatal single-dose nevirapine. AIDS. 2003 Jul 25; 17(11):1659-65. PMID: 12853748.
      View in: PubMed
    131. Ghosh MK, Kuhn L, West J, Semrau K, Decker D, Thea DM, Aldrovandi GM. Quantitation of human immunodeficiency virus type 1 in breast milk. J Clin Microbiol. 2003 Jun; 41(6):2465-70. PMID: 12791866.
      View in: PubMed
    132. Brambilla D, Jennings C, Aldrovandi G, Bremer J, Comeau AM, Cassol SA, Dickover R, Jackson JB, Pitt J, Sullivan JL, Butcher A, Grosso L, Reichelderfer P, Fiscus SA. Multicenter evaluation of use of dried blood and plasma spot specimens in quantitative assays for human immunodeficiency virus RNA: measurement, precision, and RNA stability. J Clin Microbiol. 2003 May; 41(5):1888-93. PMID: 12734222.
      View in: PubMed
    133. King JR, Acosta EP, Chadwick E, Yogev R, Crain M, Pass R, Kimberlin DW, Sturdevant MS, Aldrovandi GM. Evaluation of multiple drug therapy in human immunodeficiency virus-infected pediatric patients. Pediatr Infect Dis J. 2003 Mar; 22(3):239-44. PMID: 12634585.
      View in: PubMed
    134. King JR, Nachman S, Yogev R, Hodge J, Aldrovandi G, Damle B, Smith E, Wiznia A, Acosta EP. Single-dose pharmacokinetics of enteric-coated didanosine in HIV-infected children. Antivir Ther. 2002 Dec; 7(4):267-70. PMID: 12553481.
      View in: PubMed
    135. Tang J, Tang S, Lobashevsky E, Myracle AD, Fideli U, Aldrovandi G, Allen S, Musonda R, Kaslow RA. Favorable and unfavorable HLA class I alleles and haplotypes in Zambians predominantly infected with clade C human immunodeficiency virus type 1. J Virol. 2002 Aug; 76(16):8276-84. PMID: 12134033.
      View in: PubMed
    136. Sabbaj S, Edwards BH, Ghosh MK, Semrau K, Cheelo S, Thea DM, Kuhn L, Ritter GD, Mulligan MJ, Goepfert PA, Aldrovandi GM. Human immunodeficiency virus-specific CD8(+) T cells in human breast milk. J Virol. 2002 Aug; 76(15):7365-73. PMID: 12097549.
      View in: PubMed
    137. Hoesley CJ, Allen SA, Raper JL, Musonda R, Niu Y, Gao F, Squires KE, Aldrovandi GM. Comparative analysis of commercial assays for the detection and quantification of Human Immunodeficiency Virus Type 1 (HIV-1) RNA in plasma from patients infected with HIV-1 subtype C. Clin Infect Dis. 2002 Aug 01; 35(3):323-5. PMID: 12115099.
      View in: PubMed
    138. King JR, Kimberlin DW, Aldrovandi GM, Acosta EP. Antiretroviral pharmacokinetics in the paediatric population: a review. Clin Pharmacokinet. 2002; 41(14):1115-33. PMID: 12405863.
      View in: PubMed
    139. Allen SA, Musonda R, Trask S, Hahn BH, Weiss H, Mulenga J, Kasolo F, Vermund SH, Aldrovandi GM. Virologic and immunologic determinants of heterosexual transmission of human immunodeficiency virus type 1 in Africa. AIDS Res Hum Retroviruses. 2001 Jul 01; 17(10):901-10. PMID: 11461676.
      View in: PubMed
    140. Van Tine BA, Shaw GM, Aldrovandi G. Mother-to-infant transmission of the human immunodeficiency virus during primary infection. N Engl J Med. 1999 Nov 11; 341(20):1548. PMID: 10577111.
      View in: PubMed
    141. Aldrovandi GM, Gao L, Bristol G, Zack JA. Regions of human immunodeficiency virus type 1 nef required for function in vivo. J Virol. 1998 Sep; 72(9):7032-9. PMID: 9696795.
      View in: PubMed
    142. Koka PS, Fraser JK, Bryson Y, Bristol GC, Aldrovandi GM, Daar ES, Zack JA. Human immunodeficiency virus inhibits multilineage hematopoiesis in vivo. J Virol. 1998 Jun; 72(6):5121-7. PMID: 9573283.
      View in: PubMed
    143. Valentin A, Aldrovandi G, Zolotukhin AS, Cole SW, Zack JA, Pavlakis GN, Felber BK. Reduced viral load and lack of CD4 depletion in SCID-hu mice infected with Rev-independent clones of human immunodeficiency virus type 1. J Virol. 1997 Dec; 71(12):9817-22. PMID: 9371653.
      View in: PubMed
    144. Boldt-Houle DM, Jamieson BD, Aldrovandi GM, Rinaldo CR, Ehrlich GD, Zack JA. Loss of T cell receptor Vbeta repertoires in HIV type 1-infected SCID-hu mice. AIDS Res Hum Retroviruses. 1997 Jan 20; 13(2):125-34. PMID: 9007198.
      View in: PubMed
    145. Jamieson BD, Aldrovandi GM, Zack JA. The SCID-hu mouse: an in-vivo model for HIV-1 pathogenesis and stem cell gene therapy for AIDS. Semin Immunol. 1996 Aug; 8(4):215-21. PMID: 8883144.
      View in: PubMed
    146. Aldrovandi GM, Zack JA. Replication and pathogenicity of human immunodeficiency virus type 1 accessory gene mutants in SCID-hu mice. J Virol. 1996 Mar; 70(3):1505-11. PMID: 8627668.
      View in: PubMed
    147. Jamieson BD, Pang S, Aldrovandi GM, Zha J, Zack JA. In vivo pathogenic properties of two clonal human immunodeficiency virus type 1 isolates. J Virol. 1995 Oct; 69(10):6259-64. PMID: 7666526.
      View in: PubMed
    148. Jamieson BD, Aldrovandi GM, Planelles V, Jowett JB, Gao L, Bloch LM, Chen IS, Zack JA. Requirement of human immunodeficiency virus type 1 nef for in vivo replication and pathogenicity. J Virol. 1994 Jun; 68(6):3478-85. PMID: 8189487.
      View in: PubMed
    149. Aldrovandi GM, Feuer G, Gao L, Jamieson B, Kristeva M, Chen IS, Zack JA. The SCID-hu mouse as a model for HIV-1 infection. Nature. 1993 Jun 24; 363(6431):732-6. PMID: 8515816.
      View in: PubMed