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Yang, Otto Orlean

Title(s)Professor, Medicine
SchoolMed - Infectious Diseases
Phone3107949491
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    Title(s)Professor, Mimg


    Collapse Research 
    Collapse Research Activities and Funding
    Dual CMV and HIV CARs for Cure of HIV
    NIH/NIAID R21AI136606Mar 5, 2020 - Feb 28, 2022
    Role: Principal Investigator
    Therapeutic Anti-HIV Chimeric Antigen Receptors Via Stem Cell Delivery
    NIH/NIAID R01AI140775Jan 16, 2020 - Dec 31, 2024
    Role: Principal Investigator
    Los Angeles CRS for the MACS/WIHS Combined Cohort Study
    NIH/NHLBI U01HL146333Apr 15, 2019 - Mar 31, 2026
    Role: Co-Principal Investigator
    Chimeric Broadly Neutralizing Anti-HIV Antibodies
    NIH/NIAID R21AI131879May 11, 2018 - Apr 30, 2020
    Role: Principal Investigator
    CD4 T Cell Differentiation and Susceptibility to HIV-Specific CTL Killing
    NIH/NIAID R21AI122939Aug 16, 2016 - Jul 31, 2018
    Role: Principal Investigator
    Dissection of HIV-1 CTL Escape Pathways
    NIH/NIDCR R01DE025166Sep 13, 2014 - Aug 31, 2019
    Role: Principal Investigator
    Topical Microbicides: Targeted Intracellular Delivery
    NIH/NIAID R01AI112016Mar 1, 2014 - Feb 28, 2018
    Role: Principal Investigator
    Functional Assessment of CTL Anergy in HIV Infection
    NIH/NIAID R21AI110343Feb 1, 2014 - Jan 31, 2016
    Role: Principal Investigator
    Bio-Nanoparticles for HIV Antigen Delivery
    NIH/NIAID R21AI106528Apr 19, 2013 - Mar 31, 2015
    Role: Principal Investigator
    Mechanistic Studies of HIV-exposed Seronegative Individuals
    NIH/NIAID R56AI100638Aug 1, 2012 - Jul 31, 2014
    Role: Principal Investigator
    Identifying and closing gaps in TCR coverage of HIV-1 escape
    NIH/NIAID R56AI093138Aug 1, 2011 - Jul 31, 2013
    Role: Principal Investigator
    TRANSLATIONAL AIDS AND VIRAL PATHOGENESIS TRAINING
    NIH/NIAID T32AI089398May 15, 2010 - Jul 31, 2020
    Role: Principal Investigator
    Addressing Intra-/Inter-Clade Diversity in HIV Vaccine Design by Immune Focusing
    NIH/NIAID R21AI087382Apr 12, 2010 - Mar 31, 2013
    Role: Principal Investigator
    Mucosal and Peripheral NK-T Cells in HIV Infection
    NIH/NIAID R21AI063974Apr 1, 2006 - Mar 31, 2008
    Role: Principal Investigator
    Immune Pressure on HIV-1 Nef by Cytotoxic T Lymphocytes
    NIH/NIAID R01AI051970Apr 1, 2002 - Jun 30, 2013
    Role: Principal Investigator
    HIV-1 Escape from Inhibition by Cytotoxic T Lymphocytes
    NIH/NIAID R01AI043203Apr 1, 1998 - Mar 31, 2013
    Role: Principal Investigator
    INHIBITION OF HIV 1 BY CYTOTOXIC T LYMPHOCYTES
    NIH/NIAID K08AI001413Aug 1, 1996 - Jun 30, 1999
    Role: Principal Investigator
    INHIBITION OF HIV-1 BY CYTOTOXIC T LYMPHOCYTES
    NIH/NIAID F32AI009270Jul 1, 1996
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Brown TT, Moser C, Currier JS, Ribaudo HJ, Rothenberg J, Kelesidis T, Yang O, Dubé MP, Murphy RL, Stein JH, McComsey GA. Erratum to: Changes in Bone Mineral Density After Initiation of Antiretroviral Treatment With Tenofovir Disoproxil Fumarate/Emtricitabine Plus Atazanavir/Ritonavir, Darunavir/Ritonavir, or Raltegravir. J Infect Dis. 2020 Feb 05. PMID: 32022230.
      View in: PubMed
    2. Ali A, Furler RL, Pedroza-Martins L, Colantonio AD, Anisman-Posner D, Bryson Y, Yang OO, Uittenbogaart CH. A Novel HIV-1 Nef Mutation in a Primary Pediatric Isolate Impairs MHC-Class I Downregulation and Cytopathicity. AIDS Res Hum Retroviruses. 2020 Feb; 36(2):122-130. PMID: 31571497.
      View in: PubMed
    3. Grossman MA, Hofmann C, Ng HL, Yang OO. Suboptimal stimulation by weak agonist epitope variants does not drive dysfunction of HIV-1-specific cytotoxic T lymphocyte clones. AIDS. 2019 08 01; 33(10):1565-1574. PMID: 31306165.
      View in: PubMed
    4. Fulcher JA, Tamshen K, Wollenberg AL, Kickhoefer VA, Mrazek J, Elliott J, Ibarrondo FJ, Anton PA, Rome LH, Maynard HD, Deming T, Yang OO. Human Vault Nanoparticle Targeted Delivery of Antiretroviral Drugs to Inhibit Human Immunodeficiency Virus Type 1 Infection. Bioconjug Chem. 2019 Aug 21; 30(8):2216-2227. PMID: 31265254.
      View in: PubMed
    5. Furler RL, Ali A, Yang OO, Nixon DF. Nef-induced differential gene expression in primary CD4+ T cells following infection with HIV-1 isolates. Virus Genes. 2019 Aug; 55(4):541-544. PMID: 31093843.
      View in: PubMed
    6. Ali A, Ng HL, Blankson JN, Burton DR, Buckheit RW, Moldt B, Fulcher JA, Ibarrondo FJ, Anton PA, Yang OO. Highly Attenuated Infection With a Vpr-Deleted Molecular Clone of Human Immunodeficiency Virus-1. J Infect Dis. 2018 09 22; 218(9):1447-1452. PMID: 29878133.
      View in: PubMed
    7. Balamurugan A, Ng HL, Yang OO. Cross-Reactivity against Multiple HIV-1 Epitopes Is Characteristic of HIV-1-Specific Cytotoxic T Lymphocyte Clones. J Virol. 2018 08 15; 92(16). PMID: 29899094.
      View in: PubMed
    8. Kim J, De La Cruz J, Lam K, Ng H, Daar ES, Balamurugan A, Yang OO. CD8+ Cytotoxic T Lymphocyte Responses and Viral Epitope Escape in Acute HIV-1 Infection. Viral Immunol. 2018 09; 31(7):525-536. PMID: 30059271.
      View in: PubMed
    9. Kelesidis T, Moser CB, Johnston E, Stein JH, Dube MP, Yang OO, McComsey GA, Currier JS, Brown TT. Brief Report: Changes in Plasma RANKL-Osteoprotegerin in a Prospective, Randomized Clinical Trial of Initial Antiviral Therapy: A5260s. J Acquir Immune Defic Syndr. 2018 07 01; 78(3):362-366. PMID: 29533303.
      View in: PubMed
    10. Ding K, Zhang X, Mrazek J, Kickhoefer VA, Lai M, Ng HL, Yang OO, Rome LH, Zhou ZH. Solution Structures of Engineered Vault Particles. Structure. 2018 04 03; 26(4):619-626.e3. PMID: 29551289.
      View in: PubMed
    11. Du Y, Zhang TH, Dai L, Zheng X, Gorin AM, Oishi J, Wu TT, Yoshizawa JM, Li X, Yang OO, Martinez-Maza O, Detels R, Sun R. Effects of Mutations on Replicative Fitness and Major Histocompatibility Complex Class I Binding Affinity Are Among the Determinants Underlying Cytotoxic-T-Lymphocyte Escape of HIV-1 Gag Epitopes. mBio. 2017 11 28; 8(6). PMID: 29184023.
      View in: PubMed
    12. Leitman EM, Willberg CB, Tsai MH, Chen H, Buus S, Chen F, Riddell L, Haas D, Fellay J, Goedert JJ, Piechocka-Trocha A, Walker BD, Martin J, Deeks S, Wolinsky SM, Martinson J, Martin M, Qi Y, Sáez-Cirión A, Yang OO, Matthews PC, Carrington M, Goulder PJR. HLA-B*14:02-Restricted Env-Specific CD8+ T-Cell Activity Has Highly Potent Antiviral Efficacy Associated with Immune Control of HIV Infection. J Virol. 2017 11 15; 91(22). PMID: 28878089.
      View in: PubMed
    13. Weinstein M, Yang OO, Cohen AC. Were we prepared for PrEP? Five years of implementation. AIDS. 2017 10 23; 31(16):2303-2305. PMID: 28857829.
      View in: PubMed
    14. Homann S, Hofmann C, Gorin AM, Nguyen HCX, Huynh D, Hamid P, Maithel N, Yacoubian V, Mu W, Kossyvakis A, Sen Roy S, Yang OO, Kelesidis T. A novel rapid and reproducible flow cytometric method for optimization of transfection efficiency in cells. PLoS One. 2017; 12(9):e0182941. PMID: 28863132.
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    15. Dock J, Ramirez CM, Hultin L, Hausner MA, Hultin P, Elliott J, Yang OO, Anton PA, Jamieson BD, Effros RB. Distinct aging profiles of CD8+ T cells in blood versus gastrointestinal mucosal compartments. PLoS One. 2017; 12(8):e0182498. PMID: 28832609.
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    16. Gorin AM, Du Y, Liu FY, Zhang TH, Ng HL, Hofmann C, Cumberland WG, Sun R, Yang OO. HIV-1 epitopes presented by MHC class I types associated with superior immune containment of viremia have highly constrained fitness landscapes. PLoS Pathog. 2017 Aug; 13(8):e1006541. PMID: 28787455.
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    17. Balamurugan A, Claiborne D, Ng HL, Yang OO. HIV-1 Epitope Variability Is Associated with T Cell Receptor Repertoire Instability and Breadth. J Virol. 2017 08 15; 91(16). PMID: 28592539.
      View in: PubMed
    18. Fulcher JA, Romas L, Hoffman JC, Elliott J, Saunders T, Burgener AD, Anton PA, Yang OO. Highly Human Immunodeficiency Virus-Exposed Seronegative Men Have Lower Mucosal Innate Immune Reactivity. AIDS Res Hum Retroviruses. 2017 08; 33(8):788-795. PMID: 28503933.
      View in: PubMed
    19. Yang OO, Cumberland WG, Escobar R, Liao D, Chew KW. Demographics and natural history of HIV-1-infected spontaneous controllers of viremia. AIDS. 2017 05 15; 31(8):1091-1098. PMID: 28301422.
      View in: PubMed
    20. Shaw KL, Garabedian E, Mishra S, Barman P, Davila A, Carbonaro D, Shupien S, Silvin C, Geiger S, Nowicki B, Smogorzewska EM, Brown B, Wang X, de Oliveira S, Choi Y, Ikeda A, Terrazas D, Fu PY, Yu A, Fernandez BC, Cooper AR, Engel B, Podsakoff G, Balamurugan A, Anderson S, Muul L, Jagadeesh GJ, Kapoor N, Tse J, Moore TB, Purdy K, Rishi R, Mohan K, Skoda-Smith S, Buchbinder D, Abraham RS, Scharenberg A, Yang OO, Cornetta K, Gjertson D, Hershfield M, Sokolic R, Candotti F, Kohn DB. Clinical efficacy of gene-modified stem cells in adenosine deaminase-deficient immunodeficiency. J Clin Invest. 2017 May 01; 127(5):1689-1699. PMID: 28346229.
      View in: PubMed
    21. Dock J, Hultin L, Hultin P, Elliot J, Yang OO, Anton PA, Jamieson BD, Effros RB. Human immune compartment comparisons: Optimization of proliferative assays for blood and gut T lymphocytes. J Immunol Methods. 2017 06; 445:77-87. PMID: 28336395.
      View in: PubMed
    22. Kim JY, Kelesidis T, Yang OO. Detection of Donor-Derived Microparticles in the Peripheral Blood of a Hand Transplant Recipient During Rejection. Transplant Direct. 2017 Mar; 3(3):e131. PMID: 28361115.
      View in: PubMed
    23. Schlimgen R, Howard J, Wooley D, Thompson M, Baden LR, Yang OO, Christiani DC, Mostoslavsky G, Diamond DV, Duane EG, Byers K, Winters T, Gelfand JA, Fujimoto G, Hudson TW, Vyas JM. Risks Associated With Lentiviral Vector Exposures and Prevention Strategies. J Occup Environ Med. 2016 12; 58(12):1159-1166. PMID: 27930472.
      View in: PubMed
    24. Kelesidis T, Jackson N, McComsey GA, Wang X, Elashoff D, Dube MP, Brown TT, Yang OO, Stein JH, Currier JS. Oxidized lipoproteins are associated with markers of inflammation and immune activation in HIV-1 infection. AIDS. 2016 11 13; 30(17):2625-2633. PMID: 27603288.
      View in: PubMed
    25. Zhang X, Lai M, Chang W, Yu I, Ding K, Mrazek J, Ng HL, Yang OO, Maslov DA, Zhou ZH. Structures and stabilization of kinetoplastid-specific split rRNAs revealed by comparing leishmanial and human ribosomes. Nat Commun. 2016 10 18; 7:13223. PMID: 27752045.
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    26. Kelesidis T, Tran TTT, Brown TT, Moser C, Ribaudo HJ, Dube MP, Yang OO, McComsey GA, Stein JH, Currier JS. Changes in plasma levels of oxidized lipoproteins and lipoprotein subfractions with atazanavir-, raltegravir-, darunavir-based initial antiviral therapy and associations with common carotid artery intima-media thickness: ACTG 5260s. Antivir Ther. 2017; 22(2):113-126. PMID: 27661466.
      View in: PubMed
    27. Lake JE, Seang S, Kelesidis T, Currier JS, Yang OO. Telmisartan increases vascular reparative capacity in older HIV-infected adults: a pilot study. HIV Clin Trials. 2016 11; 17(6):225-232. PMID: 27658740.
      View in: PubMed
    28. Yang OO, Currier JS. Reimann's "Habitual Hyperthermia" Responding to Hormone Therapy. Open Forum Infect Dis. 2016 Sep; 3(3):ofw127. PMID: 27800522.
      View in: PubMed
    29. Ali A, Kitchen SG, Chen ISY, Ng HL, Zack JA, Yang OO. HIV-1-Specific Chimeric Antigen Receptors Based on Broadly Neutralizing Antibodies. J Virol. 2016 08 01; 90(15):6999-7006. PMID: 27226366.
      View in: PubMed
    30. Kelesidis T, Moser C, Stein JH, Brown TT, Tran TT, Ribaudo HJ, Dube MP, Yang OO, Currier JS, McComsey GA. Changes in Markers of T-Cell Senescence and Exhaustion With Atazanavir-, Raltegravir-, and Darunavir-Based Initial Antiviral Therapy: ACTG 5260s. J Infect Dis. 2016 09 01; 214(5):748-52. PMID: 27354367.
      View in: PubMed
    31. Aguilera-Sandoval CR, Yang OO, Jojic N, Lovato P, Chen DY, Boechat MI, Cooper P, Zuo J, Ramirez C, Belzer M, Church JA, Krogstad P. Supranormal thymic output up to 2 decades after HIV-1 infection. AIDS. 2016 Mar 13; 30(5):701-11. PMID: 26730570.
      View in: PubMed
    32. Kim JY, Balamurugan A, Azari K, Hofmann C, Ng HL, Reed EF, McDiarmid S, Yang OO. Correction: Clonal CD8+ T Cell Persistence and Variable Gene Usage Bias in a Human Transplanted Hand. PLoS One. 2015; 10(12):e0146008. PMID: 26699875.
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    33. Kim JY, Balamurugan A, Azari K, Hofmann C, Ng HL, Reed EF, McDiarmid S, Yang OO. Clonal CD8+ T Cell Persistence and Variable Gene Usage Bias in a Human Transplanted Hand. PLoS One. 2015; 10(8):e0136235. PMID: 26287728.
      View in: PubMed
    34. Zhen A, Kamata M, Rezek V, Rick J, Levin B, Kasparian S, Chen IS, Yang OO, Zack JA, Kitchen SG. HIV-specific Immunity Derived From Chimeric Antigen Receptor-engineered Stem Cells. Mol Ther. 2015 Aug; 23(8):1358-1367. PMID: 26050990.
      View in: PubMed
    35. Shen X, Duffy R, Howington R, Cope A, Sadagopal S, Park H, Pal R, Kwa S, Ding S, Yang OO, Fouda GG, Le Grand R, Bolton D, Esteban M, Phogat S, Roederer M, Amara RR, Picker LJ, Seder RA, McElrath MJ, Barnett S, Permar SR, Shattock R, DeVico AL, Felber BK, Pavlakis GN, Pantaleo G, Korber BT, Montefiori DC, Tomaras GD. Vaccine-Induced Linear Epitope-Specific Antibodies to Simian Immunodeficiency Virus SIVmac239 Envelope Are Distinct from Those Induced to the Human Immunodeficiency Virus Type 1 Envelope in Nonhuman Primates. J Virol. 2015 Aug; 89(16):8643-50. PMID: 26018159.
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    36. Kamata M, Kim PY, Ng HL, Ringpis GE, Kranz E, Chan J, O'Connor S, Yang OO, Chen IS. Ectopic expression of anti-HIV-1 shRNAs protects CD8(+) T cells modified with CD4? CAR from HIV-1 infection and alleviates impairment of cell proliferation. Biochem Biophys Res Commun. 2015 Jul 31; 463(3):216-21. PMID: 25998390.
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    37. Brown TT, Moser C, Currier JS, Ribaudo HJ, Rothenberg J, Kelesidis T, Yang O, Dubé MP, Murphy RL, Stein JH, McComsey GA. Changes in Bone Mineral Density After Initiation of Antiretroviral Treatment With Tenofovir Disoproxil Fumarate/Emtricitabine Plus Atazanavir/Ritonavir, Darunavir/Ritonavir, or Raltegravir. J Infect Dis. 2015 Oct 15; 212(8):1241-9. PMID: 25948863.
      View in: PubMed
    38. Kelesidis T, Tran TT, Stein JH, Brown TT, Moser C, Ribaudo HJ, Dube MP, Murphy R, Yang OO, Currier JS, McComsey GA. Changes in Inflammation and Immune Activation With Atazanavir-, Raltegravir-, Darunavir-Based Initial Antiviral Therapy: ACTG 5260s. Clin Infect Dis. 2015 Aug 15; 61(4):651-60. PMID: 25904376.
      View in: PubMed
    39. Preza GC, Yang OO, Elliott J, Anton PA, Ochoa MT. T lymphocyte density and distribution in human colorectal mucosa, and inefficiency of current cell isolation protocols. PLoS One. 2015; 10(4):e0122723. PMID: 25856343.
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    40. D'Souza MP, Yang OO. Adenovirus vectors as HIV-1 vaccines: where are we? What next? AIDS. 2015 Feb 20; 29(4):395-400. PMID: 25630039.
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    41. Yang OO, Ali A, Kasahara N, Faure-Kumar E, Bae JY, Picker LJ, Park H. Short conserved sequences of HIV-1 are highly immunogenic and shift immunodominance. J Virol. 2015 Jan 15; 89(2):1195-204. PMID: 25378501.
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    42. Kelesidis T, Roberts CK, Huynh D, Martínez-Maza O, Currier JS, Reddy ST, Yang OO. A high throughput biochemical fluorometric method for measuring lipid peroxidation in HDL. PLoS One. 2014; 9(11):e111716. PMID: 25368900.
      View in: PubMed
    43. Hoffman JC, Anton PA, Baldwin GC, Elliott J, Anisman-Posner D, Tanner K, Grogan T, Elashoff D, Sugar C, Yang OO, Hoffman RM. Seminal plasma HIV-1 RNA concentration is strongly associated with altered levels of seminal plasma interferon-?, interleukin-17, and interleukin-5. AIDS Res Hum Retroviruses. 2014 Nov; 30(11):1082-8. PMID: 25209674.
      View in: PubMed
    44. Yang OO, Kelesidis T, Cordova R, Khanlou H. Immunomodulation of antiretroviral drug-suppressed chronic HIV-1 infection in an oral probiotic double-blind placebo-controlled trial. AIDS Res Hum Retroviruses. 2014 Oct; 30(10):988-95. PMID: 25127924.
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    45. Chung B, Montel-Hagen A, Ge S, Blumberg G, Kim K, Klein S, Zhu Y, Parekh C, Balamurugan A, Yang OO, Crooks GM. Engineering the human thymic microenvironment to support thymopoiesis in vivo. Stem Cells. 2014 Sep; 32(9):2386-96. PMID: 24801626.
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    46. Al-Mawsawi LQ, Wu NC, De La Cruz J, Shi VC, Wu TT, Daar ES, Lewis MJ, Yang OO, Sun R. Short communication: HIV-1 gag genetic variation in a single acutely infected participant defined by high-resolution deep sequencing. AIDS Res Hum Retroviruses. 2014 Aug; 30(8):806-11. PMID: 24914638.
      View in: PubMed
    47. Kelesidis T, Currier JS, Yang OO, Brown TT. Role of RANKL-RANK/osteoprotegerin pathway in cardiovascular and bone disease associated with HIV infection. AIDS Rev. 2014 Jul-Sep; 16(3):123-33. PMID: 25102334.
      View in: PubMed
    48. Wu NC, De La Cruz J, Al-Mawsawi LQ, Olson CA, Qi H, Luan HH, Nguyen N, Du Y, Le S, Wu TT, Li X, Lewis MJ, Yang OO, Sun R. HIV-1 quasispecies delineation by tag linkage deep sequencing. PLoS One. 2014; 9(5):e97505. PMID: 24842159.
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    49. De La Cruz J, Vollbrecht T, Frohnen P, Ng HL, Daar ES, Yang OO, Lewis MJ. Ineffectual targeting of HIV-1 Nef by cytotoxic T lymphocytes in acute infection results in no functional impairment or viremia reduction. J Virol. 2014 Jul; 88(14):7881-92. PMID: 24789790.
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    50. Yang OO, Ibarrondo FJ, Price C, Hultin LE, Elliott J, Hultin PM, Shih R, Hausner MA, Ng HL, Hoffman J, Jamieson BD, Anton PA. Differential blood and mucosal immune responses against an HIV-1 vaccine administered via inguinal or deltoid injection. PLoS One. 2014; 9(2):e88621. PMID: 24558403.
      View in: PubMed
    51. Zanni MV, Kelesidis T, Fitzgerald ML, Lo J, Abbara S, Wai B, Marmarelis E, Hernandez NJ, Yang OO, Currier JS, Grinspoon SK. HDL redox activity is increased in HIV-infected men in association with macrophage activation and non-calcified coronary atherosclerotic plaque. Antivir Ther. 2014; 19(8):805-811. PMID: 24535655.
      View in: PubMed
    52. Preza GC, Tanner K, Elliott J, Yang OO, Anton PA, Ochoa MT. Antigen-presenting cell candidates for HIV-1 transmission in human distal colonic mucosa defined by CD207 dendritic cells and CD209 macrophages. AIDS Res Hum Retroviruses. 2014 Mar; 30(3):241-9. PMID: 24134315.
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    53. Ibarrondo FJ, Yang OO, Chodon T, Avramis E, Lee Y, Sazegar H, Jalil J, Chmielowski B, Koya RC, Schmid I, Gomez-Navarro J, Jamieson BD, Ribas A, Comin-Anduix B. Natural killer T cells in advanced melanoma patients treated with tremelimumab. PLoS One. 2013; 8(10):e76829. PMID: 24167550.
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    54. Lewis MJ, Frohnen P, Ibarrondo FJ, Reed D, Iyer V, Ng HL, Elliott J, Yang OO, Anton P. HIV-1 Nef sequence and functional compartmentalization in the gut is not due to differential cytotoxic T lymphocyte selective pressure. PLoS One. 2013; 8(9):e75620. PMID: 24058696.
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    55. Roberts CK, Katiraie M, Croymans DM, Yang OO, Kelesidis T. Untrained young men have dysfunctional HDL compared with strength-trained men irrespective of body weight status. J Appl Physiol (1985). 2013 Oct 01; 115(7):1043-9. PMID: 23887902.
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    56. Balamurugan A, Ali A, Boucau J, Le Gall S, Ng HL, Yang OO. HIV-1 gag cytotoxic T lymphocyte epitopes vary in presentation kinetics relative to HLA class I downregulation. J Virol. 2013 Aug; 87(15):8726-34. PMID: 23740989.
      View in: PubMed
    57. Vatakis DN, Arumugam B, Kim SG, Bristol G, Yang O, Zack JA. Introduction of exogenous T-cell receptors into human hematopoietic progenitors results in exclusion of endogenous T-cell receptor expression. Mol Ther. 2013 May; 21(5):1055-63. PMID: 23481324.
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    58. Kelesidis T, Yang OO, Kendall MA, Hodis HN, Currier JS. Dysfunctional HDL and progression of atherosclerosis in HIV-1-infected and -uninfected adults. Lipids Health Dis. 2013 Mar 05; 12:23. PMID: 23510548.
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    59. Bhattacharya D, Lewis MJ, Lassmann B, Phan T, Knecht G, Bickel M, Yang OO. Combination of allele-specific detection techniques to quantify minority resistance variants in hepatitis B infection: a novel approach. J Virol Methods. 2013 Jun; 190(1-2):34-40. PMID: 23454647.
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    60. Kelesidis T, Kendall MA, Yang OO, Hodis H, Currier JS. Perturbations of circulating levels of RANKL-osteoprotegerin axis in relation to lipids and progression of atherosclerosis in HIV-infected and -uninfected adults: ACTG NWCS 332/A5078 Study. AIDS Res Hum Retroviruses. 2013 Jun; 29(6):938-48. PMID: 23351153.
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    61. Kløverpris HN, Payne RP, Sacha JB, Rasaiyaah JT, Chen F, Takiguchi M, Yang OO, Towers GJ, Goulder P, Prado JG. Early antigen presentation of protective HIV-1 KF11Gag and KK10Gag epitopes from incoming viral particles facilitates rapid recognition of infected cells by specific CD8+ T cells. J Virol. 2013 Mar; 87(5):2628-38. PMID: 23255798.
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    62. Kelesidis T, Kendall MA, Yang OO, Hodis HN, Currier JS. Biomarkers of microbial translocation and macrophage activation: association with progression of subclinical atherosclerosis in HIV-1 infection. J Infect Dis. 2012 Nov 15; 206(10):1558-67. PMID: 23066162.
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    63. Wick WD, Yang OO. Biologically-directed modeling reflects cytolytic clearance of SIV-infected cells in vivo in macaques. PLoS One. 2012; 7(9):e44778. PMID: 23028619.
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    64. Candotti F, Shaw KL, Muul L, Carbonaro D, Sokolic R, Choi C, Schurman SH, Garabedian E, Kesserwan C, Jagadeesh GJ, Fu PY, Gschweng E, Cooper A, Tisdale JF, Weinberg KI, Crooks GM, Kapoor N, Shah A, Abdel-Azim H, Yu XJ, Smogorzewska M, Wayne AS, Rosenblatt HM, Davis CM, Hanson C, Rishi RG, Wang X, Gjertson D, Yang OO, Balamurugan A, Bauer G, Ireland JA, Engel BC, Podsakoff GM, Hershfield MS, Blaese RM, Parkman R, Kohn DB. Gene therapy for adenosine deaminase-deficient severe combined immune deficiency: clinical comparison of retroviral vectors and treatment plans. Blood. 2012 Nov 01; 120(18):3635-46. PMID: 22968453.
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    65. Brennan CA, Ibarrondo FJ, Sugar CA, Hausner MA, Shih R, Ng HL, Detels R, Margolick JB, Rinaldo CR, Phair J, Jacobson LP, Yang OO, Jamieson BD. Early HLA-B*57-restricted CD8+ T lymphocyte responses predict HIV-1 disease progression. J Virol. 2012 Oct; 86(19):10505-16. PMID: 22811521.
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    66. Kelesidis T, Reddy ST, Huynh D, Meriwether D, Fogelman AM, Navab M, Yang OO. Effects of lipid-probe interactions in biochemical fluorometric methods that assess HDL redox activity. Lipids Health Dis. 2012 Jul 06; 11:87. PMID: 22768920.
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    67. Chen DY, Balamurugan A, Ng HL, Cumberland WG, Yang OO. Epitope targeting and viral inoculum are determinants of Nef-mediated immune evasion of HIV-1 from cytotoxic T lymphocytes. Blood. 2012 Jul 05; 120(1):100-11. PMID: 22613796.
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    68. Lewis MJ, Lee P, Ng HL, Yang OO. Immune selection in vitro reveals human immunodeficiency virus type 1 Nef sequence motifs important for its immune evasion function in vivo. J Virol. 2012 Jul; 86(13):7126-35. PMID: 22553319.
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    69. Lewis MJ, Dagarag M, Khan B, Ali A, Yang OO. Partial escape of HIV-1 from cytotoxic T lymphocytes during chronic infection. J Virol. 2012 Jul; 86(13):7459-63. PMID: 22553321.
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    70. Gossett DR, Tse HT, Lee SA, Ying Y, Lindgren AG, Yang OO, Rao J, Clark AT, Di Carlo D. Hydrodynamic stretching of single cells for large population mechanical phenotyping. Proc Natl Acad Sci U S A. 2012 May 15; 109(20):7630-5. PMID: 22547795.
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    71. Kitchen SG, Levin BR, Bristol G, Rezek V, Kim S, Aguilera-Sandoval C, Balamurugan A, Yang OO, Zack JA. In vivo suppression of HIV by antigen specific T cells derived from engineered hematopoietic stem cells. PLoS Pathog. 2012; 8(4):e1002649. PMID: 22511873.
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