Shangxin Yang

Title(s)HS Associate Clinical Professor, Pathology and Laboratory Medicine
SchoolMedicine
ORCID ORCID Icon0000-0001-9991-1178 Additional info
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    Collapse Biography 
    Collapse Education and Training
    University of California, Los Angeles, Los Angeles, CAFellow06/2016Medical and Public Health Laboratory Microbiology
    University of Southern California, Los Angeles, CAPhD06/2006Biochemistry and Molecular Biology
    Peking University, BeijingBS07/2001Biotechnology

    Collapse Overview 
    Collapse Overview
    Dr. Yang is a molecular biologist and clinical microbiologist, with extensive experience in clinical microbiology, clinical virology, molecular diagnostics, microbial genomics, genomic epidemiology, antimicrobial resistance, and transplant infectious disease diagnostics. He is also a pioneer in the clinical applications of Next-generation Sequencing (NGS) in infectious diseases. Dr. Yang developed and implemented numerous cutting-edge molecular microbiological tests, and authored or coauthored over 80 peer-reviewed papers and 3 book chapters. Dr. Yang currently is an Associate Clinical Professor in the Department of Pathology and Laboratory Medicine, UCLA School of Medicine, and serves as the Associate Medical Director of the Clinical Microbiology Laboratory. Dr. Yang is also the Director of the Molecular Microbiology and Pathogen Genomics (MMPG) Laboratory, which integrates the most advanced NGS technologies with pathogen-focused bioinformatics for microbial whole-genome sequencing (WGS) and metagenomics testing, solving the unmet clinical needs in diagnosing and treating challenging infectious diseases cases. The MMPG Laboratory also performs real-time institution-level microbial genomic surveillance for outbreak investigation, emerging pathogen characterization, and AMR monitoring, providing timely and highly actionable information to guide infection prevention and treatment optimization.

    Dr. Yang graduated from Beijing University with a B.S degree in Biotechnology in 2001, and from the University of Southern California with a Ph.D. degree in Molecular Biology and Biochemistry in 2006. He received Clinical and Public Health Microbiology Fellowship training at UCLA (2014-2016) and became board certified by the American Board of Medical Microbiology (ABMM) in 2016.

    Dr. Yang's main research interests include molecular diagnostics test development and innovation, clinical applications of NGS, transplant-related infectious diseases testing, genomic epidemiology, hospital outbreak investigation, and antimicrobial resistance (AMR) mechanisms and genotypic prediction. Dr. Yang also works closely with international collaborators in the investigation and monitoring of global emerging infectious diseases and novel AMR mechanisms. He is an advocate and public speaker for vaccines, infection prevention, drug resistance and preparedness for emerging outbreaks in the community. He is also an enthusiastic educator to promote the science of microbiology and infectious diseases to the public and younger generation.
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    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Editorial: Integration of NGS in clinical and public health microbiology workflows: applications, compliance, quality considerations. Front Public Health. 2024; 12:1357098. Yang S, Kozyreva VK, Timme RE, Hemarajata P. PMID: 38322128; PMCID: PMC10845330.
      View in: PubMed   Mentions:    Fields:    Translation:PHPublic Health
    2. Elucidating the Clinical Interpretation and Impact of a Positive Plasma Cell-Free DNA Metagenomics Test Result-A Single Center Retrospective Study. J Appl Lab Med. 2024 Jan 03; 9(1):14-27. Vinh Dong H, Saleh T, Kaur I, Yang S. PMID: 38167775.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    3. Case Report: Disseminated Edwardsiella tarda infection in an immunocompromised patient. Front Cell Infect Microbiol. 2023; 13:1292768. An L, Chan JL, Nguyen M, Yang S, Deville JG. PMID: 38053529; PMCID: PMC10694257.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    4. Domestically Acquired NDM-1-Producing Pseudomonas aeruginosa, Southern California, USA, 2023. Emerg Infect Dis. 2023 11; 29(11):2382-2385. Gray HK, Beaird OE, Smith EA, Schaenman JM, Yang S. PMID: 37877613; PMCID: PMC10617354.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    5. Clinical Whole-Genome Sequencing Assay for Rapid Mycobacterium tuberculosis Complex First-Line Drug Susceptibility Testing and Phylogenetic Relatedness Analysis. Microorganisms. 2023 Oct 11; 11(10). Shaw B, von Bredow B, Tsan A, Garner O, Yang S. PMID: 37894195; PMCID: PMC10609454.
      View in: PubMed   Mentions:
    6. FDA trial regulation of laboratory developed tests (LDTs): An academic medical center's experience with Mpox in-house testing. J Clin Virol. 2023 Dec; 169:105611. Caldera JR, Gray HK, Garner OB, Yang S. PMID: 37866092.
      View in: PubMed   Mentions:    Fields:    Translation:HumansPHPublic Health
    7. Nosocomial infections by diverse carbapenemase-producing Aeromonas hydrophila associated with combination of plumbing issues and heat waves. Am J Infect Control. 2024 Mar; 52(3):337-343. Gray HK, Bisht A, Caldera JR, Fossas Braegger NM, Cambou MC, Sakona AN, Beaird OE, Uslan DZ, Walton SC, Yang S. PMID: 37778710.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCellsPHPublic Health
    8. Development of a Rapid and High-Throughput Multiplex Real-Time PCR Assay for Mycoplasma hominis and Ureaplasma Species. J Mol Diagn. 2023 Sep 07. Chan JL, Cerón S, Horiuchi SM, Yap JP, Chihuahua EG, Tsan AT, Kamau E, Yang S. PMID: 37683891.
      View in: PubMed   Mentions:    Fields:    
    9. Transient SARS-CoV-2 RNA-Dependent RNA Polymerase Mutations after Remdesivir Treatment for Chronic COVID-19 in Two Transplant Recipients: Case Report and Intra-Host Viral Genomic Investigation. Microorganisms. 2023 Aug 16; 11(8). Yang S, Multani A, Garrigues JM, Oh MS, Hemarajata P, Burleson T, Green NM, Oliai C, Gaynor PT, Beaird OE, Winston DJ, Seet CS, Schaenman JM. PMID: 37630656; PMCID: PMC10460003.
      View in: PubMed   Mentions: 2  
    10. Clinical and Genomic Characterization of Carbapenem-Resistant Klebsiella pneumoniae with Concurrent Production of NDM and OXA-48-like Carbapenemases in Southern California, 2016-2022. Microorganisms. 2023 Jun 30; 11(7). Cerón S, Salem-Bango Z, Contreras DA, Ranson EL, Yang S. PMID: 37512889; PMCID: PMC10383945.
      View in: PubMed   Mentions:
    11. Clinical next-generation sequencing assay combining full-length gene amplification and shotgun sequencing for the detection of CMV drug resistance mutations. J Clin Virol. 2023 08; 165:105520. von Bredow B, Caldera JR, Cerón S, Chan JL, Gray HK, Garner OB, Yang S. PMID: 37336174.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    12. Epidemiology and SARS-CoV-2 Infection Patterns among Youth Followed at a Large Los Angeles Health Network during 2020-2022: Clinical Presentation, Prevalent Strains, and Correlates of Disease Severity. Vaccines (Basel). 2023 May 25; 11(6). Saleh T, Fuller T, Cambou MC, Segura ER, Kamau E, Yang S, Garner OB, Nielsen-Saines K. PMID: 37376413; PMCID: PMC10300956.
      View in: PubMed   Mentions: 1  
    13. Extensively Drug-Resistant Shigella flexneri 2a, California, USA, 2022. Emerg Infect Dis. 2023 07; 29(7):1473-1475. Caldera JR, Yang S, Uslan DZ. PMID: 37204919; PMCID: PMC10310382.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    14. Metagenomic Sequencing of Positive Blood Culture Fluid for Accurate Bacterial and Fungal Species Identification: A Pilot Study. Microorganisms. 2023 May 10; 11(5). Kamau E, Yang S. PMID: 37317232; PMCID: PMC10224492.
      View in: PubMed   Mentions: 1  
    15. Accurate subspecies-level identification of clinically significant Mycobacterium avium and Mycobacterium intracellulare by whole-genome sequencing. J Microbiol Methods. 2023 05; 208:106726. Chawla R, Shaw B, von Bredow B, Chong C, Garner OB, Zangwill KM, Yang S. PMID: 37120137.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    16. Discovery of a novel sub-lineage of multi-drug resistant Shigella flexneri in Southern California. Int J Infect Dis. 2023 Jul; 132:1-3. Kamau E, Adamson PC, Crandall J, Mukhopadhyay R, Yang S. PMID: 36990199; PMCID: PMC10275642.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    17. Application of CRISPR-Based Human and Bacterial Ribosomal RNA Depletion for SARS-CoV-2 Shotgun Metagenomic Sequencing. Am J Clin Pathol. 2023 02 01; 159(2):111-115. Cerón S, Clemons NC, von Bredow B, Yang S. PMID: 36495133.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    18. Fungal Whole-Genome Sequencing for Species Identification: From Test Development to Clinical Utilization. J Fungi (Basel). 2023 Jan 29; 9(2). Salem-Bango Z, Price TK, Chan JL, Chandrasekaran S, Garner OB, Yang S. PMID: 36836298; PMCID: PMC9965959.
      View in: PubMed   Mentions: 6  
    19. Catheter-Related Bloodstream Infection Caused by Mycolicibacterium iranicum, California, USA. Emerg Infect Dis. 2023 01; 29(1):217-219. Ranson EL, Tsevat RK, von Bredow B, Kamau E, Yang S, Prabaker KK. PMID: 36573647; PMCID: PMC9796217.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    20. On variants and vaccines: The effectiveness of Covid-19 monoclonal antibody therapy during two distinct periods in the pandemic. PLoS One. 2022; 17(12):e0278394. Srinivasan V, Weinstein SE, Bhimani A, Clemons NC, Dinolfo M, Shin CS, Grier J, Lopez A, Braggs J, Boucher J, Batiste QN, Garner OB, Yang S, Vijayan T. PMID: 36454767.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCellsPHPublic Health
    21. Case report: Disseminated histoplasmosis in a renal transplant recipient from a non-endemic region. Front Pediatr. 2022; 10:985475. Chang B, Saleh T, Wales C, Kuklinski L, Malla P, Yang S, Fuller D, Nielsen-Saines K. PMID: 36452357; PMCID: PMC9701819.
      View in: PubMed   Mentions: 2  
    22. Case Report: Symptomatic Herpes Simplex Virus Type 2 and Monkeypox Coinfection in an Adult Male. Am J Trop Med Hyg. 2022 12 14; 107(6):1258-1260. Prabaker KK, de St Maurice A, Uslan DZ, Yen GC, Manavi S, Gray HK, Caldera JR, Chan JL, Garner OB, Yang S. PMID: 36375467; PMCID: PMC9768272.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    23. Clinical and genomic characterization of hypervirulent Klebsiella pneumoniae (hvKp) infections via passive surveillance in Southern California, 2020-2022. Front Microbiol. 2022; 13:1001169. Kamau E, Ranson EL, Tsan AT, Bergmann-Leitner ES, Garner OB, Yang S. PMID: 36312975; PMCID: PMC9614223.
      View in: PubMed   Mentions: 6  
    24. Endofungal Mycetohabitans rhizoxinica Bacteremia Associated with Rhizopus microsporus Respiratory Tract Infection. Emerg Infect Dis. 2022 Oct; 28(10):2091-2095. Yang S, Anikst V, Adamson PC. PMID: 36148964; PMCID: PMC9514336.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimalsCells
    25. Clinical, microbiological, and genomic characteristics of clade-III Candida auris colonization and infection in southern California, 2019-2022. Infect Control Hosp Epidemiol. 2023 Jul; 44(7):1093-1101. de St Maurice A, Parti U, Anikst VE, Harper T, Mirasol R, Dayo AJ, Garner OB, Prabaker KK, Yang S. PMID: 36052507; PMCID: PMC10369217.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimals
    26. Clinical and epidemiological characteristics of SARS-CoV-2 Infection in Los Angeles County youth during the first year of the pandemic. Int J Infect Dis. 2022 Sep; 122:514-520. Saleh T, Kerin T, Fuller T, Paiola S, Cambou MC, Motwani Y, Newhouse CN, Yang S, Kamau E, Garner OB, Chandrasekaran S, Nielsen-Saines K. PMID: 35803467; PMCID: PMC9259006.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCellsPHPublic Health
    27. Disguised as Ovarian Tumor: A Rare Case of Uterine Abscess Due to Hypervirulent Klebsiella pneumoniae Infection. Open Forum Infect Dis. 2022 Jul; 9(7):ofac321. Kamau E, Ranson EL, Zakhour M, Mayo MS, Sakona AN, Allyn PR, Yang S. PMID: 35899277; PMCID: PMC9310266.
      View in: PubMed   Mentions: 1  
    28. Investigation of SARS-CoV-2 Epsilon Variant and Hospitalization Status by Genomic Surveillance in a Single Large Health System During the 2020-2021 Winter Surge in Southern California. Am J Clin Pathol. 2022 05 04; 157(5):649-652. Yang S, Hemarajata P, Hilt EE, Price TK, Garner OB, Green NM. PMID: 34875004; PMCID: PMC8689746.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    29. Genomic epidemiology of the Los Angeles COVID-19 outbreak and the early history of the B.1.43 strain in the USA. BMC Genomics. 2022 Apr 04; 23(1):260. Guo L, Boocock J, Hilt EE, Chandrasekaran S, Zhang Y, Munugala C, Sathe L, Alexander N, Arboleda VA, Flint J, Eskin E, Luo C, Yang S, Garner OB, Yin Y, Bloom JS, Kruglyak L. PMID: 35379194; PMCID: PMC8978495.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCellsPHPublic Health
    30. Reinfection or relapse? A case study of whole genome sequencing guided genomic characterization of Mycobacterium abscessus chronic infection in a cystic fibrosis patient. IDCases. 2022; 28:e01491. Chawla R, von Bredow B, Deville J, Yang S. PMID: 35369567; PMCID: PMC8968000.
      View in: PubMed   Mentions: 1  
    31. Mycoplasma hominis infections in solid organ transplant recipients: Clinical characteristics, treatment outcomes, and comparison of phenotypic and genotypic susceptibility profiles. Transpl Infect Dis. 2022 Jun; 24(3):e13822. Chang SY, Price TK, Beaird OE, Gaynor PT, Schaenman JM, Carlson ME, Kubak BM, Yang S, Multani A. PMID: 35253965.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    32. Genomic diversity and antimicrobial resistance among non-typhoidal Salmonella associated with human disease in The Gambia. Microb Genom. 2022 03; 8(3). Darboe S, Bradbury RS, Phelan J, Kanteh A, Muhammad AK, Worwui A, Yang S, Nwakanma D, Perez-Sepulveda B, Kariuki S, Kwambana-Adams B, Antonio M. PMID: 35302932; PMCID: PMC9176284.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCells
    33. Case Report and Genomic Analysis of Cefiderocol-Resistant Escherichia coli Clinical Isolates. Am J Clin Pathol. 2022 Feb 03; 157(2):257-265. Price TK, Davar K, Contreras D, Ward KW, Garner OB, Simner PJ, Yang S, Chandrasekaran S. PMID: 34542575.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCells
    34. Retrospective Detection of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) in Symptomatic Patients Prior to Widespread Diagnostic Testing in Southern California. Clin Infect Dis. 2022 01 29; 74(2):271-277. Hilt EE, Boocock J, Trejo M, Le CQ, Guo L, Zhang Y, Sathe L, Arboleda VA, Yin Y, Bloom JS, Wang PC, Elmore JG, Kruglyak L, Shrestha L, Bakhash SAM, Lin M, Xie H, Huang ML, Roychoudhury P, Greninger A, Chandrasekaran S, Yang S, Garner OB. PMID: 33939799; PMCID: PMC8135745.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    35. AMP case report: Rhinoscleroma in Southern California—diagnosis made by multidisciplinary investigation. CAP TODAY. 2022; (2022). Edwin Kamau, PhD; Tara Narasumhalu, MD Omai Garner, PhD; Abie H. Mendelsohn, MD Jeffrey D. Goldstein, MD; Shangxin Yang, PhD. View Publication.
    36. The systemic inflammatory landscape of COVID-19 in pregnancy: Extensive serum proteomic profiling of mother-infant dyads with in utero SARS-CoV-2. Cell Rep Med. 2021 11 16; 2(11):100453. Foo SS, Cambou MC, Mok T, Fajardo VM, Jung KL, Fuller T, Chen W, Kerin T, Mei J, Bhattacharya D, Choi Y, Wu X, Xia T, Shin WJ, Cranston J, Aldrovandi G, Tobin N, Contreras D, Ibarrondo FJ, Yang O, Yang S, Garner O, Cortado R, Bryson Y, Janzen C, Ghosh S, Devaskar S, Asilnejad B, Moreira ME, Vasconcelos Z, Soni PR, Gibson LC, Brasil P, Comhair SAA, Arumugaswami V, Erzurum SC, Rao R, Jung JU, Nielsen-Saines K. PMID: 34723226; PMCID: PMC8549189.
      View in: PubMed   Mentions: 22     Fields:    Translation:Humans
    37. Utilization of whole genome sequencing for resolution of discrepant Mycobacterium tuberculosis drug susceptibility results: A case report. IDCases. 2021; 26:e01308. Realegeno S, Adeyiga O, Winston DJ, Beaird OE, Garner OB, Yang S. PMID: 34745885; PMCID: PMC8551521.
      View in: PubMed   Mentions: 1  
    38. Mycobacterium chimaera infections among cardiothoracic surgery patients associated with heater-cooler devices-Kansas and California, 2019. Infect Control Hosp Epidemiol. 2022 10; 43(10):1333-1338. Xu K, Finn LE, Geist RL, Prestel C, Moulton-Meissner H, Kim M, Stacey B, McAllister GA, Gable P, Kamali T, de St Maurice A, Yang S, Perkins KM, Crist MB. PMID: 34612179.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCellsPHPublic Health
    39. Clinical Whole Genome Sequencing for Clarithromycin and Amikacin Resistance Prediction and Subspecies Identification of Mycobacterium abscessus. J Mol Diagn. 2021 11; 23(11):1460-1467. Realegeno S, Mirasol R, Garner OB, Yang S. PMID: 34454109.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansCells
    40. Validation, Implementation, and Clinical Utility of Whole Genome Sequence-Based Bacterial Identification in the Clinical Microbiology Laboratory. J Mol Diagn. 2021 11; 23(11):1468-1477. Price TK, Realegeno S, Mirasol R, Tsan A, Chandrasekaran S, Garner OB, Yang S. PMID: 34384892.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansCellsPHPublic Health
    41. Catabacter hongkongensis bacteremia identified by direct metagenomic sequencing of positive blood culture fluid, first case report in the US. Anaerobe. 2021 Oct; 71:102421. Kamau E, Maliksi E, Kwan N, Garner OB, Yang S. PMID: 34314867.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCells
    42. Clinical Impact of Metagenomic Next-Generation Sequencing of Bronchoalveolar Lavage in the Diagnosis and Management of Pneumonia: A Multicenter Prospective Observational Study. J Mol Diagn. 2021 10; 23(10):1259-1268. Zhou H, Larkin PMK, Zhao D, Ma Q, Yao Y, Wu X, Wang J, Zhou X, Li Y, Wang G, Feng M, Wu L, Chen J, Zhou C, Hua X, Zhou J, Yang S, Yu Y. PMID: 34197923.
      View in: PubMed   Mentions: 28     Fields:    Translation:Humans
    43. Deceiving Phenotypic Susceptibility Results on a Klebsiella pneumoniae Blood Isolate Carrying Plasmid-Mediated AmpC Gene blaDHA-1. Front Cell Infect Microbiol. 2021; 11:561880. Realegeno S, Ward K, Garner OB, Yang S. PMID: 33791229; PMCID: PMC8006929.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCells
    44. Investigation of Phylogeny and Drug Resistance Mechanisms of Elizabethkingia anophelis Isolated from Blood and Lower Respiratory Tract. Microb Drug Resist. 2021 Sep; 27(9):1259-1264. Larkin PMK, Mortimer L, Malenfant JH, Gaynor P, Contreras DA, Garner OB, Yang S, Allyn P. PMID: 33656389.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCells
    45. Clinical and Epidemiologic Evaluation of Inconclusive COVID-19 PCR Results Using a Quantitative Algorithm. Am J Clin Pathol. 2021 Feb 11; 155(3):376-380. Yang S, Stanzione N, Uslan DZ, Garner OB, de St Maurice A. PMID: 33274731; PMCID: PMC7799210.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCells
    46. Clinical Impact of Metagenomic Next-Generation Sequencing of Plasma Cell-Free DNA for the Diagnosis of Infectious Diseases: A Multicenter Retrospective Cohort Study. Clin Infect Dis. 2021 01 27; 72(2):239-245. Hogan CA, Yang S, Garner OB, Green DA, Gomez CA, Dien Bard J, Pinsky BA, Banaei N. PMID: 31942944.
      View in: PubMed   Mentions: 89     Fields:    Translation:Humans
    47. Genomic Characterizations of Clade III Lineage of Candida auris, California, USA. Emerg Infect Dis. 2021; 27(4):1223-1227. Price TK, Mirasol R, Ward KW, Dayo AJ, Hilt EE, Chandrasekaran S, Garner OB, de St Maurice A, Yang S. PMID: 33755003; PMCID: PMC8007294.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansAnimals
    48. Endogenous Endophthalmitis Caused by ST66-K2 Hypervirulent Klebsiella pneumoniae, United States. Emerg Infect Dis. 2021; 27(8):2215-2218. Kamau E, Allyn PR, Beaird OE, Ward KW, Kwan N, Garner OB, Yang S. PMID: 34287130; PMCID: PMC8314818.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
    49. Performance Characteristics of Severe Acute Respiratory Syndrome Coronavirus 2 RT-PCR Tests in a Single Health System: Analysis of >10,000 Results from Three Different Assays. J Mol Diagn. 2021 02; 23(2):159-163. Price TK, Bowland BC, Chandrasekaran S, Garner OB, Yang S. PMID: 33285286; PMCID: PMC7718779.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansCells
    50. Carbapenem Resistant Aeromonas hydrophila Carrying blacphA7 Isolated From Two Solid Organ Transplant Patients. Front Cell Infect Microbiol. 2020; 10:563482. Hilt EE, Fitzwater SP, Ward K, de St Maurice A, Chandrasekaran S, Garner OB, Yang S. PMID: 33194801; PMCID: PMC7649429.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCells
    51. Seawater-Associated Highly Pathogenic Francisella hispaniensis Infections Causing Multiple Organ Failure. Emerg Infect Dis. 2020 10; 26(10):2424-2428. Zhou H, Yang Q, Shen L, Yao Y, Xu J, Ye J, Wu X, Yu Y, Li Z, Zhou J, Yang S. PMID: 32946719; PMCID: PMC7510699.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCells
    52. Epidemiological and Genomic Analysis of SARS-CoV-2 in 10 Patients From a Mid-Sized City Outside of Hubei, China in the Early Phase of the COVID-19 Outbreak. Front Public Health. 2020; 8:567621. Chen J, Hilt EE, Li F, Wu H, Jiang Z, Zhang Q, Wang J, Wang Y, Li Z, Tang J, Yang S. PMID: 33072702; PMCID: PMC7531217.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCellsPHPublic Health
    53. Diagnostic yield of repeat testing for SARS-CoV-2: Experience from a large health system in Los Angeles. Int J Infect Dis. 2020 Nov; 100:298-301. Adamson PC, Goodman-Meza D, Vijayan T, Yang S, Garner OB. PMID: 32835787; PMCID: PMC7441934.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCellsPHPublic Health
    54. Unusual presentation of meningococcal meningitis in the elderly and utility of CSF PCR testing. Access Microbiol. 2020; 2(10):acmi000158. Ranson E, Ship H, Garner O, Yang S, Bhattacharya D. PMID: 33195972; PMCID: PMC7660242.
      View in: PubMed   Mentions:
    55. Amplicon-Based Next-Generation Sequencing for Detection of Fungi in Formalin-Fixed, Paraffin-Embedded Tissues: Correlation with Histopathology and Clinical Applications. J Mol Diagn. 2020 10; 22(10):1287-1293. Larkin PMK, Lawson KL, Contreras DA, Le CQ, Trejo M, Realegeno S, Hilt EE, Chandrasekaran S, Garner OB, Fishbein GA, Yang S. PMID: 32738297.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansAnimals
    56. A Collaborative Tale of Diagnosing and Treating Chronic Pulmonary Aspergillosis, from the Perspectives of Clinical Microbiologists, Surgical Pathologists, and Infectious Disease Clinicians. J Fungi (Basel). 2020 Jul 11; 6(3). Larkin PMK, Multani A, Beaird OE, Dayo AJ, Fishbein GA, Yang S. PMID: 32664547; PMCID: PMC7558816.
      View in: PubMed   Mentions: 4  
    57. An Unusual Carbapenem Resistant Escherichia coli Carrying Plasmid-mediated AmpC and Mutated ompC in A Patient with Recurrent Urinary Tract Infections. IDCases. 2020; 20:e00781. Larkin PMK, Realegeno S, Ward KW, Garner OB, Yang S. PMID: 32420029; PMCID: PMC7215173.
      View in: PubMed   Mentions: 2  
    58. Discovery of a Novel Hypervirulent Acinetobacter baumannii Strain in a Case of Community-Acquired Pneumonia. Infect Drug Resist. 2020; 13:1147-1153. Zhou H, Larkin PMK, Huang J, Yao Y, Zhu B, Yang Q, Hua X, Zhou J, Yang S, Yu Y. PMID: 32368105; PMCID: PMC7183332.
      View in: PubMed   Mentions: 5  
    59. Coinfections of Two Strains of NDM-1- and OXA-232-Coproducing Klebsiella pneumoniae in a Kidney Transplant Patient. Antimicrob Agents Chemother. 2020 03 24; 64(4). Contreras DA, Fitzwater SP, Nanayakkara DD, Schaenman J, Aldrovandi GM, Garner OB, Yang S. PMID: 31527031; PMCID: PMC7179284.
      View in: PubMed   Mentions: 21     Fields:    Translation:HumansCells
    60. Validation and Retrospective Clinical Evaluation of a Quantitative 16S rRNA Gene Metagenomic Sequencing Assay for Bacterial Pathogen Detection in Body Fluids. J Mol Diagn. 2019 09; 21(5):913-923. Culbreath K, Melanson S, Gale J, Baker J, Li F, Saebo O, Kommedal O, Contreras D, Garner OB, Yang S. PMID: 31229651.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansCells
    61. Community acquired Stenotrophomonas maltophilia discitis: Diagnosis aided by shotgun metagenomic sequencing. Int J Infect Dis. 2019 Apr; 81:1-3. Wang G, Xu N, Yang L, Zheng F, Sai L, Zhou J, Yang S. PMID: 30684744.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansCells
    62. Diversity of upper respiratory tract infections and prevalence of Streptococcus pneumoniae colonization among patients with fever and flu-like symptoms. BMC Infect Dis. 2019 Jan 07; 19(1):24. Tang J, Chen J, He T, Jiang Z, Zhou J, Hu B, Yang S. PMID: 30616564; PMCID: PMC6323860.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCells
    63. Prediction of BK viremia by urine viral load in renal transplant patients: An analysis of BK viral load results in paired urine and plasma samples. Transpl Infect Dis. 2018 Oct; 20(5):e12952. Madden K, Janitell C, Sower D, Yang S. PMID: 29896858.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCells
    64. Real-time Utilization of Metagenomic Sequencing in the Diagnosis and Treatment Monitoring of an Invasive Adenovirus B55 Infection and Subsequent Herpes Simplex Virus Encephalitis in an Immunocompetent Young Adult. Open Forum Infect Dis. 2018 Jun; 5(6):ofy114. Fang X, Xu M, Fang Q, Tan H, Zhou J, Li Z, Li F, Yang S. PMID: 29977968; PMCID: PMC6016423.
      View in: PubMed   Mentions: 10  
    65. Selection of hyperproduction of AmpC and SME-1 in a carbapenem-resistant Serratia marcescens isolate during antibiotic therapy. J Antimicrob Chemother. 2018 05 01; 73(5):1256-1262. Hemarajata P, Amick T, Yang S, Gregson A, Holzmeyer C, Bush K, Humphries RM. PMID: 29471486.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansCells
    66. Evaluation of Diagnostic Utility of a High-Risk Human Papillomavirus PCR Test on Formalin-Fixed, Paraffin-Embedded Head and Neck Tumor Tissues. J Mol Diagn. 2018 03; 20(2):232-239. Huho AN, Yadak N, Bocklage TJ, Yang S. PMID: 29277636.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    67. Unusual carbapenem resistant but ceftriaxone and cefepime susceptible Klebsiella oxytoca isolated from a blood culture: Case report and whole-genome sequencing investigation. IDCases. 2018; 11:9-11. Yang S, Hemarajata P, Shevy L, Maciariello M, Culbreath K, Bush K, Humphries R. PMID: 29204354; PMCID: PMC5709312.
      View in: PubMed   Mentions: 6  
    68. Resistance to Ceftazidime-Avibactam Is Due to Transposition of KPC in a Porin-Deficient Strain of Klebsiella pneumoniae with Increased Efflux Activity. Antimicrob Agents Chemother. 2017 10; 61(10). Nelson K, Hemarajata P, Sun D, Rubio-Aparicio D, Tsivkovski R, Yang S, Sebra R, Kasarskis A, Nguyen H, Hanson BM, Leopold S, Weinstock G, Lomovskaya O, Humphries RM. PMID: 28739787; PMCID: PMC5610495.
      View in: PubMed   Mentions: 78     Fields:    Translation:HumansCells
    69. Association Between Breast Milk Bacterial Communities and Establishment and Development of the Infant Gut Microbiome. JAMA Pediatr. 2017 07 01; 171(7):647-654. Pannaraj PS, Li F, Cerini C, Bender JM, Yang S, Rollie A, Adisetiyo H, Zabih S, Lincez PJ, Bittinger K, Bailey A, Bushman FD, Sleasman JW, Aldrovandi GM. PMID: 28492938; PMCID: PMC5710346.
      View in: PubMed   Mentions: 401     Fields:    Translation:Humans
    70. Evolution and Transmission of Carbapenem-Resistant Klebsiella pneumoniae Expressing the blaOXA-232 Gene During an Institutional Outbreak Associated With Endoscopic Retrograde Cholangiopancreatography. Clin Infect Dis. 2017 Apr 01; 64(7):894-901. Yang S, Hemarajata P, Hindler J, Li F, Adisetiyo H, Aldrovandi G, Sebra R, Kasarskis A, MacCannell D, Didelot X, Russell D, Rubin Z, Humphries R. PMID: 28362935.
      View in: PubMed   Mentions: 28     Fields:    Translation:HumansCellsPHPublic Health
    71. Microbial recovery from clot-activating Vacutainers®. Diagn Microbiol Infect Dis. 2016 Aug; 85(4):395-7. Yang S, McHardy IH, Hemarajata P, Wu MT, Garner OB. PMID: 27306117.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    72. Risk factors associated with the transmission of carbapenem-resistant Enterobacteriaceae via contaminated duodenoscopes. Gastrointest Endosc. 2016 Jun; 83(6):1121-9. Kim S, Russell D, Mohamadnejad M, Makker J, Sedarat A, Watson RR, Yang S, Hemarajata P, Humphries R, Rubin Z, Muthusamy VR. PMID: 26993149.
      View in: PubMed   Mentions: 21     Fields:    Translation:HumansCellsPHPublic Health
    73. Investigation of a suspected nosocomial transmission of blaKPC3-mediated carbapenem-resistant Klebsiella pneumoniae by whole genome sequencing. Diagn Microbiol Infect Dis. 2016 Apr; 84(4):337-42. Yang S, Hemarajata P, Hindler J, Ward K, Adisetiyo H, Li F, Aldrovandi GM, Green NM, Russell D, Rubin Z, Humphries RM. PMID: 26867964.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    74. First Report of Ceftazidime-Avibactam Resistance in a KPC-3-Expressing Klebsiella pneumoniae Isolate. Antimicrob Agents Chemother. 2015 Oct; 59(10):6605-7. Humphries RM, Yang S, Hemarajata P, Ward KW, Hindler JA, Miller SA, Gregson A. PMID: 26195508; PMCID: PMC4576121.
      View in: PubMed   Mentions: 114     Fields:    Translation:Cells
    75. Development of a novel real-time PCR assay with high-resolution melt analysis to detect and differentiate OXA-48-Like β-lactamases in carbapenem-resistant Enterobacteriaceae. Antimicrob Agents Chemother. 2015 Sep; 59(9):5574-80. Hemarajata P, Yang S, Hindler JA, Humphries RM. PMID: 26124164; PMCID: PMC4538549.
      View in: PubMed   Mentions: 13     Fields:    Translation:Cells
    76. Human parechovirus central nervous system infections in southern California children. Pediatr Infect Dis J. 2014 Apr; 33(4):e87-91. Felsenstein S, Yang S, Eubanks N, Sobrera E, Grimm JP, Aldrovandi G. PMID: 24104958.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansCells
    77. Runx2 regulates survivin expression in prostate cancer cells. Lab Invest. 2010 Feb; 90(2):222-33. Lim M, Zhong C, Yang S, Bell AM, Cohen MB, Roy-Burman P. PMID: 19949374; PMCID: PMC2815261.
      View in: PubMed   Mentions: 40     Fields:    Translation:HumansAnimalsCells
    78. A novel bone morphogenetic protein signaling in heterotypic cell interactions in prostate cancer. Cancer Res. 2008 Jan 01; 68(1):198-205. Yang S, Pham LK, Liao CP, Frenkel B, Reddi AH, Roy-Burman P. PMID: 18172312.
      View in: PubMed   Mentions: 31     Fields:    Translation:AnimalsCells
    79. Bone morphogenetic protein 7 protects prostate cancer cells from stress-induced apoptosis via both Smad and c-Jun NH2-terminal kinase pathways. Cancer Res. 2006 Apr 15; 66(8):4285-90. Yang S, Lim M, Pham LK, Kendall SE, Reddi AH, Altieri DC, Roy-Burman P. PMID: 16618753.
      View in: PubMed   Mentions: 21     Fields:    Translation:HumansCells
    80. Increased expression of osteopontin contributes to the progression of prostate cancer. Cancer Res. 2006 Jan 15; 66(2):883-8. Khodavirdi AC, Song Z, Yang S, Zhong C, Wang S, Wu H, Pritchard C, Nelson PS, Roy-Burman P. PMID: 16424021.
      View in: PubMed   Mentions: 48     Fields:    Translation:HumansAnimalsCells
    81. Diverse biological effect and Smad signaling of bone morphogenetic protein 7 in prostate tumor cells. Cancer Res. 2005 Jul 01; 65(13):5769-77. Yang S, Zhong C, Frenkel B, Reddi AH, Roy-Burman P. PMID: 15994952.
      View in: PubMed   Mentions: 56     Fields:    Translation:HumansCells
    82. Aberration in the expression of the retinoid receptor, RXRalpha, in prostate cancer. Cancer Biol Ther. 2003 Mar-Apr; 2(2):179-84. Zhong C, Yang S, Huang J, Cohen MB, Roy-Burman P. PMID: 12750559.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansAnimalsCells
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