Carla Janzen

Title(s)	Professor, Obstetrics and Gynecology
School	Medicine
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Research

research activities and funding

Imaging Innovations for Placental Assessment in Response to Environmental Pollution
NIH U01HD087221Sep 17, 2015 - Aug 31, 2019
Role: Co-Principal Investigator

Bibliographic

selected publications

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.

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Fertility and Pregnancy Outcomes in Primary Hyperparathyroidism: Observations From a Large Insured Population. J Clin Endocrinol Metab. 2025 Apr 22; 110(5):1427-1433. Sant VR, Zhou H, Zhou MM, Adams AL, Ryan DS, Case SK, Seo YJ, Haigh PI, Janzen C, Yeh MW. PMID: 38867506.

View in: PubMed Mentions: Fields:
End Endocrinology Met Metabolism
Translation:Humans
Diet, polycyclic aromatic hydrocarbons, and oxidative stress biomarkers in pregnancy: A Los Angeles pregnancy cohort. Environ Res. 2025 Jun 15; 275:121399. Yu KE, Mitra S, Meng Q, DelRosario I, Devaskar SU, Janzen C, Sullivan PS, Chen L, Jerrett M, Ritz B. PMID: 40088999.

View in: PubMed Mentions: Fields:
Env Environmental Health
Ambient exposure to fine particulate matter with oxidative potential affects oxidative stress biomarkers in pregnancy. Am J Epidemiol. 2025 Jan 08; 194(1):27-34. Meng Q, Liu J, Shen J, Del Rosario I, Janzen C, Devaskar SU, Lakey PSJ, Shiraiwa M, Weichenthal S, Zhu Y, Oroumiyeh F, Banerjee S, Paulson SE, Jerrett M, Paul KC, Ritz B. PMID: 38918040; PMCID: PMC11735968.

View in: PubMed Mentions: 3 Fields:
Epi Epidemiology
Translation:Humans PHPublic Health
Does Amsterdam criteria applied to largely unsubmitted term placentas with favorable fetal outcomes show significant maternal clinicopathologic correlation? Am J Clin Pathol. 2025 Jan 06. Fortes PA, Janzen C, Lei MYY, Vangala S, Sung K, Devaskar SU, Sullivan PS. PMID: 39761233; PMCID: PMC12086057.

View in: PubMed Mentions: Fields:
Pat Pathology
Urinary polycyclic aromatic hydrocarbon metabolites and their association with oxidative stress among pregnant women in Los Angeles. Environ Health. 2024 Aug 13; 23(1):68. Meng Q, Mitra S, Del Rosario I, Jerrett M, Janzen C, Devaskar SU, Ritz B. PMID: 39138494; PMCID: PMC11321171.

View in: PubMed Mentions: Fields:
Env Environmental Health
Translation:Humans PHPublic Health
Circulating extracellular vesicular microRNA signatures in early gestation show an association with subsequent clinical features of pre-eclampsia. Sci Rep. 2024 07 22; 14(1):16770. Ghosh S, Thamotharan S, Fong J, Lei MYY, Janzen C, Devaskar SU. PMID: 39039088; PMCID: PMC11263608.

View in: PubMed Mentions: 2 Fields:
Sci Science
Translation:Humans Cells
Urinary polycyclic aromatic hydrocarbon metabolites and their association with oxidative stress among pregnant women in Los Angeles. Res Sq. 2024 Mar 20. Meng Q, Mitra S, Del Rosario I, Jerrett M, Janzen C, Devaskar SU, Ritz B. PMID: 38562764; PMCID: PMC10984082.

View in: PubMed Mentions:
Association Between Gestational Diabetes Mellitus and Hypertension: A Systematic Review and Meta-Analysis of Cohort Studies With a Quantitative Bias Analysis of Uncontrolled Confounding. Hypertension. 2024 Jun; 81(6):1257-1268. Liu X, Nianogo RA, Janzen C, Fei Z, Seamans MJ, Wen R, Li X, Chen L. PMID: 38501243.

View in: PubMed Mentions: 1 Fields:
Vas Vascular Diseases
Translation:Humans
Prevalence of maternal hyperglycemic subtypes by race/ethnicity and associations between these subtypes with adverse pregnancy outcomes: Findings from a large retrospective multi-ethnic cohort in the United States. Diabetes Res Clin Pract. 2024 Mar; 209:111576. Liu X, Janzen C, Zhu Y, Seamans M, Fei Z, Nianogo R, Chen L. PMID: 38360094.

View in: PubMed Mentions: Fields:
End Endocrinology
Translation:Humans
Alpha-1 antitrypsin deficiency and pregnancy complications and birth outcomes: A population-based cohort study in Denmark. PLoS One. 2024; 19(1):e0296434. Orimoloye HT, He D, Li T, Janzen C, Barjaktarevic I, Wang X, Hansen J, Heck JE. PMID: 38166066; PMCID: PMC10760838.

View in: PubMed Mentions: 2 Fields:
Med Medicine (General)Sci Science
Translation:Humans
Maternal dietary patterns and placental outcomes among pregnant women in Los Angeles. Placenta. 2024 01; 145:72-79. Meng Q, Del Rosario I, Sung K, Janzen C, Devaskar SU, Carpenter CL, Ritz B. PMID: 38100961; PMCID: PMC11419549.

View in: PubMed Mentions: 1 Fields:
Emb Embryology Obs Obstetrics Phy Physiology
Translation:Humans Animals
Gestational diabetes mellitus and risk of neurodevelopmental disorders in young offspring: does the risk differ by race and ethnicity? Am J Obstet Gynecol MFM. 2024 01; 6(1):101217. Liu X, Zhu Y, Seamans M, Nianogo R, Janzen C, Fei Z, Chen L. PMID: 37940104.

View in: PubMed Mentions: 2 Fields:
Gyn Gynecology Obs Obstetrics
Translation:Humans
Preeclampsia, antihypertensive medication use in pregnancy and risk of childhood cancer in offspring. Cancer Causes Control. 2024 Jan; 35(1):43-53. Askins L, Orimoloye HT, Deng C, Hansen J, Olsen J, Ritz B, Janzen C, Heck JE. PMID: 37535154; PMCID: PMC10764520.

View in: PubMed Mentions: 4 Fields:
Epi Epidemiology Neo Neoplasms
Translation:Humans
Early pregnancy imaging predicts ischemic placental disease. Placenta. 2023 09 07; 140:90-99. Lee B, Janzen C, Aliabadi AR, Lei MYY, Wu H, Liu D, Vangala SS, Devaskar SU, Sung K. PMID: 37549442; PMCID: PMC11090111.

View in: PubMed Mentions: 1 Fields:
Emb Embryology Obs Obstetrics Phy Physiology
Translation:Humans
PRENATAL MATERNAL CHARACTERISTICS ASSOCIATED WITH RETINOPATHY OF PREMATURITY. Retina. 2023 02 01; 43(2):230-237. Strawbridge JC, Chu A, Dammann O, Hanson J, Janzen C, Tsui I. PMID: 36695795.

View in: PubMed Mentions: 2 Fields:
Oph Ophthalmology
Translation:Humans
Utility of In Vivo Magnetic Resonance Imaging Is Predictive of Gestational Diabetes Mellitus During Early Pregnancy. J Clin Endocrinol Metab. 2023 01 17; 108(2):281-294. Lee B, Janzen C, Wu H, Vangala SS, Devaskar SU, Sung K. PMID: 36251771; PMCID: PMC9844964.

View in: PubMed Mentions: 2 Fields:
End Endocrinology Met Metabolism
Translation:Humans
A Description of the Imaging Innovations for Placental Assessment in Response to Environmental Pollution Study. Am J Perinatol. 2024 05; 41(S 01):e853-e862. Janzen C, Lei MYY, Lee BR, Vangala S, DelRosario I, Meng Q, Ritz B, Liu J, Jerrett M, Chanlaw T, Choi S, Aliabadi A, Fortes PA, Sullivan PS, Murphy A, Vecchio GD, Thamotharan S, Sung K, Devaskar SU. PMID: 36241211; PMCID: PMC11111287.

View in: PubMed Mentions: 8 Fields:
Per Perinatology
Translation:Humans
Evaluation of Spatial Attentive Deep Learning for Automatic Placental Segmentation on Longitudinal MRI. J Magn Reson Imaging. 2023 05; 57(5):1533-1540. Liu Y, Zabihollahy F, Yan R, Lee B, Janzen C, Devaskar SU, Sung K. PMID: 37021577; PMCID: PMC10080136.

View in: PubMed Mentions: 5 Fields:
Dia Diagnostic Imaging
Translation:Humans
Circulating extracellular vesicles exhibit a differential miRNA profile in gestational diabetes mellitus pregnancies. PLoS One. 2022; 17(5):e0267564. Thamotharan S, Ghosh S, James-Allan L, Lei MYY, Janzen C, Devaskar SU. PMID: 35613088; PMCID: PMC9132306.

View in: PubMed Mentions: 9 Fields:
Med Medicine (General)Sci Science
Translation:Humans Cells
The systemic inflammatory landscape of COVID-19 in pregnancy: Extensive serum proteomic profiling of mother-infant dyads with in utero SARS-CoV-2. Cell Rep Med. 2021 11 16; 2(11):100453. Foo SS, Cambou MC, Mok T, Fajardo VM, Jung KL, Fuller T, Chen W, Kerin T, Mei J, Bhattacharya D, Choi Y, Wu X, Xia T, Shin WJ, Cranston J, Aldrovandi G, Tobin N, Contreras D, Ibarrondo FJ, Yang O, Yang S, Garner O, Cortado R, Bryson Y, Janzen C, Ghosh S, Devaskar S, Asilnejad B, Moreira ME, Vasconcelos Z, Soni PR, Gibson LC, Brasil P, Comhair SAA, Arumugaswami V, Erzurum SC, Rao R, Jung JU, Nielsen-Saines K. PMID: 34723226; PMCID: PMC8549189.

View in: PubMed Mentions: 30 Fields:
Med Medicine (General)
Maternal Optical Coherence Tomography Angiography Changes Related to Small for Gestational Age Pregnancies. Transl Vis Sci Technol. 2020 12; 9(13):4. Su L, Lin BR, Lin F, Tsui IK, Gaw SL, Janzen C, Sadda SR, Tsui I. PMID: 33344048; PMCID: PMC7718826.

View in: PubMed Mentions: 4 Fields:
Bio Biomedical Engineering Oph Ophthalmology
Translation:Humans
Characterization of Uterine Motion in Early Gestation Using MRI-Based Motion Tracking. Diagnostics (Basel). 2020 Oct 19; 10(10). Martin T, Janzen C, Li X, Del Rosario I, Chanlaw T, Choi S, Armstrong T, Masamed R, Wu HH, Devaskar SU, Sung K. PMID: 33086473; PMCID: PMC7603139.

View in: PubMed Mentions: 6
Cell-free DNA Methylation and Transcriptomic Signature Prediction of Pregnancies with Adverse Outcomes. Epigenetics. 2021 06; 16(6):642-661. Del Vecchio G, Li Q, Li W, Thamotharan S, Tosevska A, Morselli M, Sung K, Janzen C, Zhou X, Pellegrini M, Devaskar SU. PMID: 33045922; PMCID: PMC8143248.

View in: PubMed Mentions: 29 Fields:
Gen Genetics
Translation:Humans Cells
Diminished viability of human ovarian cancer cells by antigen-specific delivery of carbon monoxide with a family of photoactivatable antibody-photoCORM conjugates. Chem Sci. 2020 Jan 14; 11(2):467-473. Kawahara B, Gao L, Cohn W, Whitelegge JP, Sen S, Janzen C, Mascharak PK. PMID: 32190266; PMCID: PMC7067254.

View in: PubMed Mentions: 13
Human Placenta Blood Flow During Early Gestation With Pseudocontinuous Arterial Spin Labeling MRI. J Magn Reson Imaging. 2020 04; 51(4):1247-1257. Liu D, Shao X, Danyalov A, Chanlaw T, Masamed R, Wang DJJ, Janzen C, Devaskar SU, Sung K. PMID: 31680405; PMCID: PMC7654100.

View in: PubMed Mentions: 14 Fields:
Dia Diagnostic Imaging
Translation:Humans
Retinal Vascular Changes During Pregnancy Detected With Optical Coherence Tomography Angiography. Invest Ophthalmol Vis Sci. 2019 06 03; 60(7):2726-2732. Chanwimol K, Balasubramanian S, Nassisi M, Gaw SL, Janzen C, Sarraf D, Sadda SR, Tsui I. PMID: 31247113.

View in: PubMed Mentions: 21 Fields:
Oph Ophthalmology
Translation:Humans
Aldehyde dehydrogenase isoforms and inflammatory cell populations are differentially expressed in term human placentas affected by intrauterine growth restriction. Placenta. 2019 06; 81:9-17. Chu A, Najafzadeh P, Sullivan P, Cone B, Elshimali R, Shakeri H, Janzen C, Mah V, Wadehra M. PMID: 31138432; PMCID: PMC6719708.

View in: PubMed Mentions: 9 Fields:
Emb Embryology Obs Obstetrics Phy Physiology
Translation:Humans Cells
Neurodevelopment in Infants Exposed to Zika Virus In Utero. N Engl J Med. 2018 12 13; 379(24):2377-2379. Lopes Moreira ME, Nielsen-Saines K, Brasil P, Kerin T, Damasceno L, Pone M, Carvalho LMA, Pone SM, Vasconcelos Z, Ribeiro IP, Zin AA, Tsui I, Adachi K, Gaw SL, Halai UA, Salles TS, da Cunha DC, Bonaldo MC, Raja Gabaglia C, Guida L, Malacarne J, Costa RP, Gomes SC, Reis AB, Soares FVM, Hasue RH, Aizawa CYP, Genovesi FF, Aibe M, Einspieler C, Marschik PB, Pereira JP, Portari EA, Janzen C, Cherry JD. PMID: 30575464; PMCID: PMC6478167.

View in: PubMed Mentions: 52 Fields:
Med Medicine (General)
Translation:Humans Cells
Carbon monoxide sensitizes cisplatin-resistant ovarian cancer cell lines toward cisplatin via attenuation of levels of glutathione and nuclear metallothionein. J Inorg Biochem. 2019 02; 191:29-39. Kawahara B, Ramadoss S, Chaudhuri G, Janzen C, Sen S, Mascharak PK. PMID: 30458366.

View in: PubMed Mentions: 26 Fields:
Bio Biochemistry
Translation:Humans Cells
Fetal programming and Wilms tumor. Pediatr Blood Cancer. 2019 01; 66(1):e27461. Heck JE, He D, Janzen C, Federman N, Olsen J, Ritz B, Hansen J. PMID: 30255546; PMCID: PMC6530460.

View in: PubMed Mentions: 10 Fields:
Hem Hematology Neo Neoplasms Ped Pediatrics
Translation:Humans
Identification of novel PIEZO1 variants using prenatal exome sequencing and correlation to ultrasound and autopsy findings of recurrent hydrops fetalis. Am J Med Genet A. 2018 12; 176(12):2829-2834. Datkhaeva I, Arboleda VA, Senaratne TN, Nikpour G, Meyerson C, Geng Y, Afshar Y, Scibetta E, Goldstein J, Quintero-Rivera F, Crandall BF, Grody WW, Deignan J, Janzen C. PMID: 30244526.

View in: PubMed Mentions: 13 Fields:
Gen Genetics
Translation:Humans
3D R2* mapping of the placenta during early gestation using free-breathing multiecho stack-of-radial MRI at 3T. J Magn Reson Imaging. 2019 01; 49(1):291-303. Armstrong T, Liu D, Martin T, Masamed R, Janzen C, Wong C, Chanlaw T, Devaskar SU, Sung K, Wu HH. PMID: 30142239; PMCID: PMC6298804.

View in: PubMed Mentions: 13 Fields:
Dia Diagnostic Imaging
Translation:Humans
Prenatal air pollution exposure, smoking, and uterine vascular resistance. Environ Epidemiol. 2018 Sep; 2(3). Contreras ZA, Heck JE, Lee PC, Cui X, Hobel CJ, Janzen C, Lurmann F, Ritz B. PMID: 30627692; PMCID: PMC6322670.

View in: PubMed Mentions: 3
Pilot Study of Intra-Aortic Balloon Occlusion to Limit Morbidity in Patients with Adherent Placentation Undergoing Cesarean Hysterectomy. AJP Rep. 2018 Apr; 8(2):e57-e63. Blumenthal E, Rao R, Murphy A, Gornbein J, Hong R, Moriarty JM, Kahn DA, Janzen C. PMID: 29651358; PMCID: PMC5895466.

View in: PubMed Mentions: 3
Humanin (HN) and glucose transporter 8 (GLUT8) in pregnancies complicated by intrauterine growth restriction. PLoS One. 2018; 13(3):e0193583. Janzen C, Lei MYY, Jeong ISD, Ganguly A, Sullivan P, Paharkova V, Capodanno G, Nakamura H, Perry A, Shin BC, Lee KW, Devaskar SU. PMID: 29590129; PMCID: PMC5873989.

View in: PubMed Mentions: 10 Fields:
Med Medicine (General)Sci Science
Translation:Humans Cells
Measuring human placental blood flow with multidelay 3D GRASE pseudocontinuous arterial spin labeling at 3T. J Magn Reson Imaging. 2018 06; 47(6):1667-1676. Shao X, Liu D, Martin T, Chanlaw T, Devaskar SU, Janzen C, Murphy AM, Margolis D, Sung K, Wang DJJ. PMID: 29135072; PMCID: PMC5951737.

View in: PubMed Mentions: 28 Fields:
Dia Diagnostic Imaging
Translation:Humans
Prenatal Growth Patterns and Birthweight Are Associated With Differential DNA Methylation and Gene Expression of Cardiometabolic Risk Genes in Human Placentas: A Discovery-Based Approach. Reprod Sci. 2018 04; 25(4):523-539. Chen PY, Chu A, Liao WW, Rubbi L, Janzen C, Hsu FM, Thamotharan S, Ganguly A, Lam L, Montoya D, Pellegrini M, Devaskar SU. PMID: 28693373; PMCID: PMC6348426.

View in: PubMed Mentions: 31 Fields:
Rep Reproductive Medicine
Translation:Humans Cells
Epithelial membrane protein 2 (EMP2) deficiency alters placental angiogenesis, mimicking features of human placental insufficiency. J Pathol. 2017 06; 242(2):246-259. Williams CJ, Chu A, Jefferson WN, Casero D, Sudhakar D, Khurana N, Hogue CP, Aryasomayajula C, Patel P, Sullivan P, Padilla-Banks E, Mohandessi S, Janzen C, Wadehra M. PMID: 28295343; PMCID: PMC5444952.

View in: PubMed Mentions: 14 Fields:
Pat Pathology
Differential microRNA expression in human placentas of term intra-uterine growth restriction that regulates target genes mediating angiogenesis and amino acid transport. PLoS One. 2017; 12(5):e0176493. Thamotharan S, Chu A, Kempf K, Janzen C, Grogan T, Elashoff DA, Devaskar SU. PMID: 28463968; PMCID: PMC5413012.

View in: PubMed Mentions: 23 Fields:
Med Medicine (General)Sci Science
Translation:Humans Cells
The Role of Epithelial to Mesenchymal Transition in Human Amniotic Membrane Rupture. J Clin Endocrinol Metab. 2017 04 01; 102(4):1261-1269. Janzen C, Sen S, Lei MY, Gagliardi de Assumpcao M, Challis J, Chaudhuri G. PMID: 28388726; PMCID: PMC5460731.

View in: PubMed Mentions: 36 Fields:
End Endocrinology Met Metabolism
Translation:Humans
Zika Virus Infection in Pregnant Women in Rio de Janeiro. N Engl J Med. 2016 12 15; 375(24):2321-2334. Brasil P, Pereira JP, Moreira ME, Ribeiro Nogueira RM, Damasceno L, Wakimoto M, Rabello RS, Valderramos SG, Halai UA, Salles TS, Zin AA, Horovitz D, Daltro P, Boechat M, Raja Gabaglia C, Carvalho de Sequeira P, Pilotto JH, Medialdea-Carrera R, Cotrim da Cunha D, Abreu de Carvalho LM, Pone M, Machado Siqueira A, Calvet GA, Rodrigues Baião AE, Neves ES, Nassar de Carvalho PR, Hasue RH, Marschik PB, Einspieler C, Janzen C, Cherry JD, Bispo de Filippis AM, Nielsen-Saines K. PMID: 26943629; PMCID: PMC5323261.

View in: PubMed Mentions: 839 Fields:
Med Medicine (General)
A pregnant dilemma: primary hyperparathyroidism due to parathyromatosis in pregnancy. Endocr Pract. 2014 Feb; 20(2):e14-7. Edling KL, Korenman SG, Janzen C, Sohsman MY, Apple SK, Bhuta S, Yeh MW. PMID: 24013984.

View in: PubMed Mentions: 16 Fields:
End Endocrinology
Placental glucose transporter 3 (GLUT3) is up-regulated in human pregnancies complicated by late-onset intrauterine growth restriction. Placenta. 2013 Nov; 34(11):1072-8. Janzen C, Lei MY, Cho J, Sullivan P, Shin BC, Devaskar SU. PMID: 24011442; PMCID: PMC3843645.

View in: PubMed Mentions: 43 Fields:
Emb Embryology Obs Obstetrics Phy Physiology
Translation:Humans Cells
Congenital malformations associated with assisted reproductive technology: a California statewide analysis. J Pediatr Surg. 2013 Jun; 48(6):1218-24. Kelley-Quon LI, Tseng CH, Janzen C, Shew SB. PMID: 23845610.

View in: PubMed Mentions: 10 Fields:
Gen General Surgery Ped Pediatrics
Translation:Humans
BabySTEPS: a sugar tracking electronic portal system for gestational diabetes. Stud Health Technol Inform. 2013; 192:1123. Arnold CW, Nguyen T, Janzen C. PMID: 23920897.

View in: PubMed Mentions: 1 Fields:
Hea Health Services Research Med Medical Informatics Tec Technology
Translation:Humans
Protein phosphatase 2A promotes endothelial survival via stabilization of translational inhibitor 4E-BP1 following exposure to tumor necrosis factor-α. Arterioscler Thromb Vasc Biol. 2011 Nov; 31(11):2586-94. Janzen C, Sen S, Cuevas J, Reddy ST, Chaudhuri G. PMID: 21903942; PMCID: PMC3206633.

View in: PubMed Mentions: 6 Fields:
Vas Vascular Diseases
Serum levels of soluble vascular cell adhesion molecule-1 are decreased in women receiving oral contraceptives compared with normally menstruating women: implications in atherosclerosis. Fertil Steril. 2005 May; 83(5):1480-8. Souter I, Janzen C, Martinez-Maza O, Breen EC, Stanczyk F, Chaudhuri G, Nathan L. PMID: 15866588.

View in: PubMed Mentions: 3 Fields:
Rep Reproductive Medicine
Translation:Humans