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Holden H Wu

Title(s)Associate Professor-in-Residence, Radiological Sciences
SchoolMedicine
Address300 Medical Plaza B130
Los Angeles CA 90024
Phone76843
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    Collapse Research 
    Collapse Research Activities and Funding
    Quantifying Body Composition and Liver Disease in Children using Free-Breathing MRI and MRE
    NIH R01DK124417May 8, 2020 - Feb 29, 2024
    Role: Principal Investigator
    Integrating Quantitative MRI and Artificial Intelligence to Improve Prostate Cancer Classification
    NIH R01CA248506Mar 1, 2020 - Feb 28, 2025
    Role: Co-Principal Investigator
    Validating Cardiac MRI Biomarkers and Genotype-Phenotype Correlations for DMD
    NIH R01HL131975Apr 1, 2016 - Mar 31, 2021
    Role: Co-Principal Investigator

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    Collapse Clinical Trials

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    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. T1-Mapping and extracellular volume estimates in pediatric subjects with Duchenne muscular dystrophy and healthy controls at 3T. J Cardiovasc Magn Reson. 2020 12 10; 22(1):85. Maforo NG, Magrath P, Moulin K, Shao J, Kim GH, Prosper A, Renella P, Wu HH, Halnon N, Ennis DB. PMID: 33302967.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    2. Characterization of Uterine Motion in Early Gestation Using MRI-Based Motion Tracking. Diagnostics (Basel). 2020 Oct 19; 10(10). Martin T, Janzen C, Li X, Del Rosario I, Chanlaw T, Choi S, Armstrong T, Masamed R, Wu HH, Devaskar SU, Sung K. PMID: 33086473.
      View in: PubMed   Mentions:
    3. Magnetic resonance imaging of high-intensity focused ultrasound-stimulated drug release from a self-reporting core@shell nanoparticle platform. Chem Commun (Camb). 2020 Sep 14; 56(71):10297-10300. Cheng CA, Chen W, Zhang L, Wu HH, Zink JI. PMID: 32756711.
      View in: PubMed   Mentions:    Fields:    
    4. A generalized system of tissue-mimicking materials for computed tomography and magnetic resonance imaging. Phys Med Biol. 2020 07 21; 65(13):13NT01. Singhrao K, Fu J, Gao Y, Wu HH, Yang Y, Hu P, Lewis JH. PMID: 32252048.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    5. Automatic needle tracking using Mask R-CNN for MRI-guided percutaneous interventions. Int J Comput Assist Radiol Surg. 2020 Oct; 15(10):1673-1684. Li X, Young AS, Raman SS, Lu DS, Lee YH, Tsao TC, Wu HH. PMID: 32676870.
      View in: PubMed   Mentions:    Fields:    
    6. Prostate Microstructure in Prostate Cancer Using 3-T MRI with Diffusion-Relaxation Correlation Spectrum Imaging: Validation with Whole-Mount Digital Histopathology. Radiology. 2020 08; 296(2):348-355. Zhang Z, Wu HH, Priester A, Magyar C, Afshari Mirak S, Shakeri S, Mohammadian Bajgiran A, Hosseiny M, Azadikhah A, Sung K, Reiter RE, Sisk AE, Raman S, Enzmann DR. PMID: 32515678.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    7. A novel anthropomorphic multimodality phantom for MRI-based radiotherapy quality assurance testing. Med Phys. 2020 Apr; 47(4):1443-1451. Singhrao K, Fu J, Wu HH, Hu P, Kishan AU, Chin RK, Lewis JH. PMID: 31954078.
      View in: PubMed   Mentions:    Fields:    
    8. Real-time 3T MRI-guided cardiovascular catheterization in a porcine model using a glass-fiber epoxy-based guidewire. PLoS One. 2020; 15(2):e0229711. Li X, Perotti LE, Martinez JA, Duarte-Vogel SM, Ennis DB, Wu HH. PMID: 32102092.
      View in: PubMed   Mentions:    Fields:    Translation:Animals
    9. Tumescent Injections in Subcutaneous Pig Tissue Disperse Fluids Volumetrically and Maintain Elevated Local Concentrations of Additives for Several Hours, Suggesting a Treatment for Drug Resistant Wounds. Pharm Res. 2020 Feb 10; 37(3):51. Koulakis JP, Rouch J, Huynh N, Wu HH, Dunn JCY, Putterman S. PMID: 32043171.
      View in: PubMed   Mentions:    Fields:    Translation:Animals
    10. MRI-guided targeted needle placement during motion using hydrostatic actuators. Int J Med Robot. 2020 Apr; 16(2):e2041. Mikaiel S, Simonelli J, Li X, Lee YH, Lee YS, Sung K, Lu DS, Tsao TC, Wu HH. PMID: 31674721.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    11. A Responsive Mesoporous Silica Nanoparticle Platform for Magnetic Resonance Imaging-Guided High-Intensity Focused Ultrasound-Stimulated Cargo Delivery with Controllable Location, Time, and Dose. J Am Chem Soc. 2019 11 06; 141(44):17670-17684. Cheng CA, Chen W, Zhang L, Wu HH, Zink JI. PMID: 31604010.
      View in: PubMed   Mentions: 4     Fields:    Translation:AnimalsCells
    12. Prostate diffusion MRI with minimal echo time using eddy current nulled convex optimized diffusion encoding. J Magn Reson Imaging. 2020 05; 51(5):1526-1539. Zhang Z, Moulin K, Aliotta E, Shakeri S, Afshari Mirak S, Hosseiny M, Raman S, Ennis DB, Wu HH. PMID: 31625663.
      View in: PubMed   Mentions:    Fields:    
    13. A nanoparticle enabled focused ultrasound-stimulated magnetic resonance imaging spotlight. Chem Commun (Camb). 2019 Aug 22; 55(69):10261-10264. Deng T, Zhang L, Wu HH, Zink JI. PMID: 31393462.
      View in: PubMed   Mentions: 1     Fields:    
    14. A variable flip angle golden-angle-ordered 3D stack-of-radial MRI technique for simultaneous proton resonant frequency shift and T1 -based thermometry. Magn Reson Med. 2019 12; 82(6):2062-2076. Zhang L, Armstrong T, Li X, Wu HH. PMID: 31257639.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimals
    15. Deep transfer learning-based prostate cancer classification using 3 Tesla multi-parametric MRI. Abdom Radiol (NY). 2019 06; 44(6):2030-2039. Zhong X, Cao R, Shakeri S, Scalzo F, Lee Y, Enzmann DR, Wu HH, Raman SS, Sung K. PMID: 30460529.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    16. Free-breathing 3-D quantification of infant body composition and hepatic fat using a stack-of-radial magnetic resonance imaging technique. Pediatr Radiol. 2019 06; 49(7):876-888. Armstrong T, Ly KV, Ghahremani S, Calkins KL, Wu HH. PMID: 31001664.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    17. Repeatability and reproducibility of variable flip angle T1 quantification in the prostate at 3 T. J Magn Reson Imaging. 2019 06; 49(6):1730-1735. Zhong X, Shakeri S, Liu D, Sayre J, Raman SS, Wu HH, Sung K. PMID: 30548513.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    18. 3D R2* mapping of the placenta during early gestation using free-breathing multiecho stack-of-radial MRI at 3T. J Magn Reson Imaging. 2019 01; 49(1):291-303. Armstrong T, Liu D, Martin T, Masamed R, Janzen C, Wong C, Chanlaw T, Devaskar SU, Sung K, Wu HH. PMID: 30142239.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    19. A system using patient-specific 3D-printed molds to spatially align in vivo MRI with ex vivo MRI and whole-mount histopathology for prostate cancer research. J Magn Reson Imaging. 2019 01; 49(1):270-279. Wu HH, Priester A, Khoshnoodi P, Zhang Z, Shakeri S, Afshari Mirak S, Asvadi NH, Ahuja P, Sung K, Natarajan S, Sisk A, Reiter R, Raman S, Enzmann D. PMID: 30069968.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    20. Liver MR Elastography at 3 T: Agreement Across Pulse Sequences and Effect of Liver R2* on Image Quality. AJR Am J Roentgenol. 2018 09; 211(3):588-594. Felker ER, Choi KS, Sung K, Wu HH, Raman SS, Bolster BD, Kannengiesser S, Sorge K, Lu DSK. PMID: 29995500.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    21. Prostate DCE-MRI with B 1 + correction using an approximated analytical approach. Magn Reson Med. 2018 12; 80(6):2525-2537. Zhong X, Martin T, Wu HH, Nayak KS, Sung K. PMID: 29770495.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    22. Free-breathing quantification of hepatic fat in healthy children and children with nonalcoholic fatty liver disease using a multi-echo 3-D stack-of-radial MRI technique. Pediatr Radiol. 2018 07; 48(7):941-953. Armstrong T, Ly KV, Murthy S, Ghahremani S, Kim GHJ, Calkins KL, Wu HH. PMID: 29728744.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    23. Free-breathing liver fat quantification using a multiecho 3D stack-of-radial technique. Magn Reson Med. 2018 Jan; 79(1):370-382. Armstrong T, Dregely I, Stemmer A, Han F, Natsuaki Y, Sung K, Wu HH. PMID: 28419582.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    24. Optimization and evaluation of reference region variable flip angle (RR-VFA) B1+ and T1 Mapping in the Prostate at 3T. J Magn Reson Imaging. 2017 03; 45(3):751-760. Rangwala NA, Dregely I, Wu HH, Sung K. PMID: 27532669.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    25. Convex optimized diffusion encoding (CODE) gradient waveforms for minimum echo time and bulk motion-compensated diffusion-weighted MRI. Magn Reson Med. 2017 02; 77(2):717-729. Aliotta E, Wu HH, Ennis DB. PMID: 26900872.
      View in: PubMed   Mentions: 22     Fields:    Translation:Humans
    26. Rapid quantitative T2 mapping of the prostate using three-dimensional dual echo steady state MRI at 3T. Magn Reson Med. 2016 12; 76(6):1720-1729. Dregely I, Margolis DA, Sung K, Zhou Z, Rangwala N, Raman SS, Wu HH. PMID: 26765746.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    27. Contrast Enhancement Patterns after Irreversible Electroporation: Experimental Study of CT Perfusion Correlated to Histopathology in Normal Porcine Liver. J Vasc Interv Radiol. 2016 Jan; 27(1):104-11. Chung DJ, Sung K, Osuagwu FC, Wu HH, Lassman C, Lu DS. PMID: 26547121.
      View in: PubMed   Mentions: 5     Fields:    Translation:Animals
    28. Fast 3D T2 -weighted imaging using variable flip angle transition into driven equilibrium (3D T2 -TIDE) balanced SSFP for prostate imaging at 3T. Magn Reson Med. 2015 Aug; 74(2):442-51. Srinivasan S, Wu HH, Sung K, Margolis DJ, Ennis DB. PMID: 25195659.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    29. Convex gradient optimization for increased spatiotemporal resolution and improved accuracy in phase contrast MRI. Magn Reson Med. 2014 Dec; 72(6):1552-64. Middione MJ, Wu HH, Ennis DB. PMID: 24347040.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
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