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Dan Ruan

Title(s)Associate Professor-in-Residence, Radiation Oncology
SchoolMedicine
Phone310-825-9771
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Ginn JS, Low DA, Lamb JM, Ruan D. A Motion Prediction Confidence Estimation Framework for Prediction-Based Radiotherapy Gating. Med Phys. 2020 May 16. PMID: 32415857.
      View in: PubMed
    2. Pan X, Levin-Epstein R, Huang J, Ruan D, King CR, Kishan AU, Steinberg ML, Qi XS. Dosimetric predictors of patient-reported toxicity after prostate stereotactic body radiotherapy: Analysis of full range of the dose-volume histogram using ensemble machine learning. Radiother Oncol. 2020 Apr 17; 148:181-188. PMID: 32388444.
      View in: PubMed
    3. Levin-Epstein R, Qiao-Guan G, Juarez JE, Shen Z, Steinberg ML, Ruan D, Valle L, Nickols NG, Kupelian PA, King CR, Cao M, Kishan AU. Clinical Assessment of Prostate Displacement and Planning Target Volume Margins for Stereotactic Body Radiotherapy of Prostate Cancer. Front Oncol. 2020; 10:539. PMID: 32373529.
      View in: PubMed
    4. Kalbasi A, Kamrava M, Chu FI, Telesca D, Van Dams R, Yang Y, Ruan D, Nelson SD, Dry SM, Hernandez J, Chmielowski B, Singh AS, Bukata SV, Bernthal NM, Steinberg ML, Weidhaas JB, Eilber FC. A Phase II Trial of 5-Day Neoadjuvant Radiotherapy for Patients with High-Risk Primary Soft Tissue Sarcoma. Clin Cancer Res. 2020 Apr 15; 26(8):1829-1836. PMID: 32054730.
      View in: PubMed
    5. Gu W, Ruan D, Lyu Q, Zou W, Dong L, Sheng K. A novel energy layer optimization framework for spot-scanning proton arc therapy. Med Phys. 2020 Feb 10. PMID: 32040214.
      View in: PubMed
    6. Lyu Q, Neph R, Yu VY, Ruan D, Boucher S, Sheng K. Many-isocenter optimization for robotic radiotherapy. Phys Med Biol. 2020 Feb 10; 65(4):045003. PMID: 31851958.
      View in: PubMed
    7. Singhrao K, Ruan D, Fu J, Gao Y, Chee G, Yang Y, King C, Hu P, Kishan AU, Lewis JH. Quantification of fiducial marker visibility for MRI-only prostate radiotherapy simulation. Phys Med Biol. 2020 Feb 05; 65(3):035015. PMID: 31881546.
      View in: PubMed
    8. McKenzie EM, Santhanam A, Ruan D, O'Connor D, Cao M, Sheng K. Multimodality image registration in the head-and-neck using a deep learning-derived synthetic CT as a bridge. Med Phys. 2020 Mar; 47(3):1094-1104. PMID: 31853975.
      View in: PubMed
    9. Ginn JS, Ruan D, Low DA, Lamb JM. An image regression motion prediction technique for MRI-guided radiotherapy evaluated in single-plane cine imaging. Med Phys. 2020 Feb; 47(2):404-413. PMID: 31808161.
      View in: PubMed
    10. Woods K, Nguyen D, Neph R, Ruan D, O'Connor D, Sheng K. A sparse orthogonal collimator for small animal intensity-modulated radiation therapy part I: Planning system development and commissioning. Med Phys. 2019 Dec; 46(12):5703-5713. PMID: 31621920.
      View in: PubMed
    11. Chan ST, Ruan D, Shaverdian N, Raghavan G, Cao M, Lee P. Effect of Radiation Doses to the Heart on Survival for Stereotactic Ablative Radiotherapy for Early-stage Non-Small-cell Lung Cancer: An Artificial Neural Network Approach. Clin Lung Cancer. 2020 Mar; 21(2):136-144.e1. PMID: 31932217.
      View in: PubMed
    12. Fu J, Yang Y, Singhrao K, Ruan D, Chu FI, Low DA, Lewis JH. Deep learning approaches using 2D and 3D convolutional neural networks for generating male pelvic synthetic computed tomography from magnetic resonance imaging. Med Phys. 2019 Sep; 46(9):3788-3798. PMID: 31220353.
      View in: PubMed
    13. Landers A, O'Connor D, Ruan D, Sheng K. Automated 4p radiotherapy treatment planning with evolving knowledge-base. Med Phys. 2019 Sep; 46(9):3833-3843. PMID: 31233619.
      View in: PubMed
    14. Zhao T, McNitt-Gray M, Ruan D. A convolutional neural network for ultra-low-dose CT denoising and emphysema screening. Med Phys. 2019 Sep; 46(9):3941-3950. PMID: 31220358.
      View in: PubMed
    15. Gu W, Neph R, Ruan D, Zou W, Dong L, Sheng K. Robust beam orientation optimization for intensity-modulated proton therapy. Med Phys. 2019 Aug; 46(8):3356-3370. PMID: 31169917.
      View in: PubMed
    16. Guo M, Chee G, O'Connell D, Dhou S, Fu J, Singhrao K, Ionascu D, Ruan D, Lee P, Low DA, Zhao J, Lewis JH. Reconstruction of a high-quality volumetric image and a respiratory motion model from patient CBCT projections. Med Phys. 2019 Aug; 46(8):3627-3639. PMID: 31087359.
      View in: PubMed
    17. Lyu Q, Neph R, Yu VY, Ruan D, Sheng K. Single-arc VMAT optimization for dual-layer MLC. Phys Med Biol. 2019 05 02; 64(9):095028. PMID: 30844772.
      View in: PubMed
    18. Gu W, Ruan D, O'Connor D, Zou W, Dong L, Tsai MY, Jia X, Sheng K. Robust optimization for intensity-modulated proton therapy with soft spot sensitivity regularization. Med Phys. 2019 Mar; 46(3):1408-1425. PMID: 30570164.
      View in: PubMed
    19. Ginn JS, Ruan D, Low DA, Lamb JM. Multislice motion modeling for MRI-guided radiotherapy gating. Med Phys. 2019 Feb; 46(2):465-474. PMID: 30570755.
      View in: PubMed
    20. Zhao T, Hoffman J, McNitt-Gray M, Ruan D. Ultra-low-dose CT image denoising using modified BM3D scheme tailored to data statistics. Med Phys. 2019 Jan; 46(1):190-198. PMID: 30351450.
      View in: PubMed
    21. Lyu Q, Yu VY, Ruan D, Neph R, O'Connor D, Sheng K. A novel optimization framework for VMAT with dynamic gantry couch rotation. Phys Med Biol. 2018 06 13; 63(12):125013. PMID: 29786614.
      View in: PubMed
    22. Lyu Q, O'Connor D, Ruan D, Yu V, Nguyen D, Sheng K. VMAT optimization with dynamic collimator rotation. Med Phys. 2018 Jun; 45(6):2399-2410. PMID: 29659018.
      View in: PubMed
    23. Gu W, O'Connor D, Nguyen D, Yu VY, Ruan D, Dong L, Sheng K. Integrated beam orientation and scanning-spot optimization in intensity-modulated proton therapy for brain and unilateral head and neck tumors. Med Phys. 2018 Apr; 45(4):1338-1350. PMID: 29394454.
      View in: PubMed
    24. O'Connor D, Yu V, Nguyen D, Ruan D, Sheng K. Fraction-variant beam orientation optimization for non-coplanar IMRT. Phys Med Biol. 2018 02 15; 63(4):045015. PMID: 29351088.
      View in: PubMed
    25. Landers A, Neph R, Scalzo F, Ruan D, Sheng K. Performance Comparison of Knowledge-Based Dose Prediction Techniques Based on Limited Patient Data. Technol Cancer Res Treat. 2018 01 01; 17:1533033818811150. PMID: 30411666.
      View in: PubMed
    26. Nguyen D, O'Connor D, Ruan D, Sheng K. Deterministic direct aperture optimization using multiphase piecewise constant segmentation. Med Phys. 2017 Nov; 44(11):5596-5609. PMID: 28834556.
      View in: PubMed
    27. Zhao T, Ruan D. A general framework to learn surrogate relevance criterion for atlas based image segmentation. Phys Med Biol. 2016 09 07; 61(17):6502-14. PMID: 27524268.
      View in: PubMed
    28. Nguyen D, Lyu Q, Ruan D, O'Connor D, Low DA, Sheng K. A comprehensive formulation for volumetric modulated arc therapy planning. Med Phys. 2016 Jul; 43(7):4263. PMID: 27370141.
      View in: PubMed
    29. Zhao T, Ruan D. Learning image based surrogate relevance criterion for atlas selection in segmentation. Phys Med Biol. 2016 06 07; 61(11):4223-34. PMID: 27192550.
      View in: PubMed
    30. Zhao T, Ruan D. Image segmentation with a novel regularized composite shape prior based on surrogate study. Med Phys. 2016 May; 43(5):2187. PMID: 27147330.
      View in: PubMed
    31. Liu W, Cheung Y, Sawant A, Ruan D. A robust real-time surface reconstruction method on point clouds captured from a 3D surface photogrammetry system. Med Phys. 2016 May; 43(5):2353. PMID: 27147347.
      View in: PubMed
    32. Nguyen D, Ruan D, O'Connor D, Woods K, Low DA, Boucher S, Sheng K. A novel software and conceptual design of the hardware platform for intensity modulated radiation therapy. Med Phys. 2016 Feb; 43(2):917-29. PMID: 26843252.
      View in: PubMed
    33. Zhao T, Ruan D. Fusion set selection with surrogate metric in multi-atlas based image segmentation. Phys Med Biol. 2016 Feb 07; 61(3):1136-54. PMID: 26760496.
      View in: PubMed
    34. Liu W, Cheung Y, Sabouri P, Arai TJ, Sawant A, Ruan D. A continuous surface reconstruction method on point cloud captured from a 3D surface photogrammetry system. Med Phys. 2015 Nov; 42(11):6564-71. PMID: 26520747.
      View in: PubMed
    35. Yu VY, Tran A, Nguyen D, Cao M, Ruan D, Low DA, Sheng K. The development and verification of a highly accurate collision prediction model for automated noncoplanar plan delivery. Med Phys. 2015 Nov; 42(11):6457-67. PMID: 26520735.
      View in: PubMed
    36. Zhao T, Ruan D. Two-stage atlas subset selection in multi-atlas based image segmentation. Med Phys. 2015 Jun; 42(6):2933-41. PMID: 26127047.
      View in: PubMed
    37. Nguyen D, O'Connor D, Yu VY, Ruan D, Cao M, Low DA, Sheng K. Dose domain regularization of MLC leaf patterns for highly complex IMRT plans. Med Phys. 2015 Apr; 42(4):1858-70. PMID: 25832076.
      View in: PubMed
    38. Qi XS, Ruan D, Lee SP, Pham A, Kupelian P, Low DA, Steinberg M, Demarco J. Dependence of achievable plan quality on treatment technique and planning goal refinement: a head-and-neck intensity modulated radiation therapy application. Int J Radiat Oncol Biol Phys. 2015 Mar 15; 91(4):817-24. PMID: 25752396.
      View in: PubMed
    39. Ruan D, Thomas D, Low DA. Objective function to obtain multiple representative waveforms for a novel helical CT scan protocol. Med Phys. 2015 Mar; 42(3):1164-9. PMID: 25735271.
      View in: PubMed
    40. Liu W, Ruan D. A unified variational segmentation framework with a level-set based sparse composite shape prior. Phys Med Biol. 2015 Mar 07; 60(5):1865-77. PMID: 25668234.
      View in: PubMed
    41. Liu W, Sung K, Ruan D. Shape-based motion correction in dynamic contrast-enhanced MRI for quantitative assessment of renal function. Med Phys. 2014 Dec; 41(12):122302. PMID: 25471978.
      View in: PubMed
    42. Kishan AU, Wang PC, Sheng K, Yu V, Ruan D, Cao M, Tenn S, Low DA, Lee P. Correlation of Clinical and Dosimetric Parameters With Radiographic Lung Injury Following Stereotactic Body Radiotherapy. Technol Cancer Res Treat. 2015 Aug; 14(4):411-8. PMID: 25261069.
      View in: PubMed
    43. Xie Q, Ruan D. Low-complexity atlas-based prostate segmentation by combining global, regional, and local metrics. Med Phys. 2014 Apr; 41(4):041909. PMID: 24694140.
      View in: PubMed
    44. Thomas D, Lamb J, White B, Jani S, Gaudio S, Lee P, Ruan D, McNitt-Gray M, Low D. A novel fast helical 4D-CT acquisition technique to generate low-noise sorting artifact-free images at user-selected breathing phases. Int J Radiat Oncol Biol Phys. 2014 May 01; 89(1):191-8. PMID: 24613815.
      View in: PubMed
    45. Yu V, Kishan AU, Cao M, Low D, Lee P, Ruan D. Dose impact in radiographic lung injury following lung SBRT: Statistical analysis and geometric interpretation. Med Phys. 2014 Mar; 41(3):031701. PMID: 24593705.
      View in: PubMed
    46. Nguyen D, Dong P, Long T, Ruan D, Low DA, Romeijn E, Sheng K. Integral dose investigation of non-coplanar treatment beam geometries in radiotherapy. Med Phys. 2014 Jan; 41(1):011905. PMID: 24387513.
      View in: PubMed
    47. Dong P, Nguyen D, Ruan D, King C, Long T, Romeijn E, Low DA, Kupelian P, Steinberg M, Yang Y, Sheng K. Feasibility of prostate robotic radiation therapy on conventional C-arm linacs. Pract Radiat Oncol. 2014 Jul-Aug; 4(4):254-60. PMID: 25012834.
      View in: PubMed
    48. Liu W, Ruan D. Estimating nonrigid motion from inconsistent intensity with robust shape features. Med Phys. 2013 Dec; 40(12):121912. PMID: 24320523.
      View in: PubMed
    49. Sayre GA, Ruan D. Dose-shaping using targeted sparse optimization. Med Phys. 2013 Jul; 40(7):071711. PMID: 23822415.
      View in: PubMed
    50. Dong P, Lee P, Ruan D, Long T, Romeijn E, Low DA, Kupelian P, Abraham J, Yang Y, Sheng K. 4p noncoplanar stereotactic body radiation therapy for centrally located or larger lung tumors. Int J Radiat Oncol Biol Phys. 2013 Jul 01; 86(3):407-13. PMID: 23523322.
      View in: PubMed
    51. Dong P, Lee P, Ruan D, Long T, Romeijn E, Yang Y, Low D, Kupelian P, Sheng K. 4p non-coplanar liver SBRT: a novel delivery technique. Int J Radiat Oncol Biol Phys. 2013 Apr 01; 85(5):1360-6. PMID: 23154076.
      View in: PubMed
    52. Ruan D, Shao W, Demarco J, Tenn S, King C, Low D, Kupelian P, Steinberg M. Evolving treatment plan quality criteria from institution-specific experience. Med Phys. 2012 May; 39(5):2708-12. PMID: 22559641.
      View in: PubMed
    53. Ruan D, Kupelian P, Low DA. Image-guided positioning and tracking. Cancer J. 2011 May-Jun; 17(3):155-8. PMID: 21610468.
      View in: PubMed