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FURVENT: Phase 3 trial of firmonertinib vs chemotherapy as first-line treatment for advanced NSCLC with EGFR exon 20 insertion mutations (FURMO-004). Lung Cancer. 2025 Jan; 199:108066.
Spira A, Cho BC, Felip E, Garon EB, Goto K, Johnson M, Leighl N, Passaro A, Planchard D, Popat S, Yang JC, Lu X, Jiang Y, Huang J, Lam M, Kowanetz M, Wang S, Le J, Hsu JY, Zhou CC. PMID: 39764938.
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RELAY: Final Overall Survival for Erlotinib Plus Ramucirumab or Placebo in Untreated, EGFR-Mutated Metastatic NSCLC. J Thorac Oncol. 2024 Nov 30.
Nakagawa K, Garon EB, Seto T, Nishio M, Aix SP, Paz-Ares L, Chiu CH, Park K, Novello S, Nadal E, Nishino K, Yoh K, Shih JY, Chik JYK, Moro-Sibilot D, Puri T, Chacko Varughese S, Frimodt-Moller B, Visseren-Grul C, Reck M. PMID: 39622410.
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PubMed Mentions: Fields:
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Characteristics of a CCL21-gene modified dendritic cell vaccine utilized for a clinical trial in non-small cell lung cancer. Mol Cancer Ther. 2024 Nov 19.
Oh MS, Dumitras C, Salehi-Rad R, Tran LM, Krysan K, Lim RJ, Jing Z, Tappuni S, Lisberg A, Garon EB, Dubinett SM, Liu B. PMID: 39559833.
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PubMed Mentions: Fields:
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CTLA4 blockade abrogates KEAP1/STK11-related resistance to PD-(L)1 inhibitors. Nature. 2024 Nov; 635(8038):462-471.
Skoulidis F, Araujo HA, Do MT, Qian Y, Sun X, Cobo AG, Le JT, Montesion M, Palmer R, Jahchan N, Juan JM, Min C, Yu Y, Pan X, Arbour KC, Vokes N, Schmidt ST, Molkentine D, Owen DH, Memmott R, Patil PD, Marmarelis ME, Awad MM, Murray JC, Hellyer JA, Gainor JF, Dimou A, Bestvina CM, Shu CA, Riess JW, Blakely CM, Pecot CV, Mezquita L, Tabbó F, Scheffler M, Digumarthy S, Mooradian MJ, Sacher AG, Lau SCM, Saltos AN, Rotow J, Johnson RP, Liu C, Stewart T, Goldberg SB, Killam J, Walther Z, Schalper K, Davies KD, Woodcock MG, Anagnostou V, Marrone KA, Forde PM, Ricciuti B, Venkatraman D, Van Allen EM, Cummings AL, Goldman JW, Shaish H, Kier M, Katz S, Aggarwal C, Ni Y, Azok JT, Segal J, Ritterhouse L, Neal JW, Lacroix L, Elamin YY, Negrao MV, Le X, Lam VK, Lewis WE, Kemp HN, Carter B, Roth JA, Swisher S, Lee R, Zhou T, Poteete A, Kong Y, Takehara T, Paula AG, Parra Cuentas ER, Behrens C, Wistuba II, Zhang J, Blumenschein GR, Gay C, Byers LA, Gibbons DL, Tsao A, Lee JJ, Bivona TG, Camidge DR, Gray JE, Lieghl N, Levy B, Brahmer JR, Garassino MC, Gandara DR, Garon EB, Rizvi NA, Scagliotti GV, Wolf J, Planchard D, Besse B, Herbst RS, Wakelee HA, Pennell NA, Shaw AT, Jänne PA, Carbone DP, Hellmann MD, Rudin CM, Albacker L, Mann H, Zhu Z, Lai Z, Stewart R, Peters S, Johnson ML, Wong KK, Huang A, Winslow MM, Rosen MJ, Winters IP, Papadimitrakopoulou VA, Cascone T, Jewsbury P, Heymach JV. PMID: 39385035; PMCID: PMC11560846.
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PubMed Mentions:
1 Fields:
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Capmatinib in MET exon 14-mutated non-small-cell lung cancer: final results from the open-label, phase 2 GEOMETRY mono-1 trial. Lancet Oncol. 2024 Oct; 25(10):1357-1370.
Wolf J, Hochmair M, Han JY, Reguart N, Souquet PJ, Smit EF, Orlov SV, Vansteenkiste J, Nishio M, de Jonge M, Akerley W, Garon EB, Groen HJM, Tan DSW, Seto T, Frampton GM, Robeva A, Carbini M, Le Mouhaer S, Yovine A, Boran A, Bossen C, Yang Y, Ji L, Fairchild L, Heist RS. PMID: 39362249.
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PubMed Mentions:
1 Fields:
Translation:
HumansCTClinical Trials
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Neoantigen immunogenicity landscapes and evolution of tumor ecosystems during immunotherapy with nivolumab. Nat Med. 2024 Nov; 30(11):3209-3222.
Alban TJ, Riaz N, Parthasarathy P, Makarov V, Kendall S, Yoo SK, Shah R, Weinhold N, Srivastava R, Ma X, Krishna C, Mok JY, van Esch WJE, Garon E, Akerley W, Creelan B, Aanur N, Chowell D, Geese WJ, Rizvi NA, Chan TA. PMID: 39349627.
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PubMed Mentions:
1 Fields:
Translation:
HumansCells
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Durvalumab With or Without Tremelimumab in Combination With Chemotherapy in First-Line Metastatic NSCLC: Five-Year Overall Survival Outcomes From the Phase 3 POSEIDON Trial. J Thorac Oncol. 2024 Sep 05.
Peters S, Cho BC, Luft AV, Alatorre-Alexander J, Geater SL, Laktionov K, Trukhin D, Kim SW, Ursol GM, Hussein M, Lim FL, Yang CT, Araujo LH, Saito H, Reinmuth N, Lowery C, Mann H, Stewart R, Jiang H, Garon EB, Mok T, Johnson ML. PMID: 39243945.
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PubMed Mentions: Fields:
Translation:
HumansCTClinical Trials
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Detecting HLA loss of heterozygosity within a standard diagnostic sequencing workflow for prognostic and therapeutic opportunities. NPJ Precis Oncol. 2024 Aug 05; 8(1):174.
Lozac'hmeur A, Danek T, Yang Q, Rosasco MG, Welch JS, Go WY, Ng EW, Mardiros A, Maloney DG, Garon EB, Kirtane K, Simeone DM, Molina JR, Salahudeen AA, Stein MM, Hecht JR. PMID: 39103508; PMCID: PMC11300791.
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PubMed Mentions:
1
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Author Correction: Cost-effective methylome sequencing of cell-free DNA for accurately detecting and locating cancer. Nat Commun. 2024 May 01; 15(1):3693.
Stackpole ML, Zeng W, Li S, Liu CC, Zhou Y, He S, Yeh A, Wang Z, Sun F, Li Q, Yuan Z, Yildirim A, Chen PJ, Winograd P, Tran B, Lee YT, Li PS, Noor Z, Yokomizo M, Ahuja P, Zhu Y, Tseng HR, Tomlinson JS, Garon E, French S, Magyar CE, Dry S, Lajonchere C, Geschwind D, Choi G, Saab S, Alber F, Wong WH, Dubinett SM, Aberle DR, Agopian V, Han SB, Ni X, Li W, Zhou XJ. PMID: 38693151; PMCID: PMC11063198.
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PubMed Mentions: Fields:
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A Brief Report of Durvalumab With or Without Tremelimumab in Combination With Chemotherapy as First-Line Therapy for Metastatic Non-Small-Cell Lung Cancer: Outcomes by Tumor PD-L1 Expression in the Phase 3 POSEIDON Study. Clin Lung Cancer. 2024 May; 25(3):266-273.e5.
Garon EB, Cho BC, Luft A, Alatorre-Alexander J, Geater SL, Trukhin D, Kim SW, Ursol G, Hussein M, Lim FL, Yang CT, Araujo LH, Saito H, Reinmuth N, Kohlmann M, Lowery C, Mann H, Peters S, Mok TS, Johnson ML. PMID: 38584069.
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PubMed Mentions: Fields:
Translation:
HumansCTClinical Trials
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Accelerated Hypofractionated Chemoradiation Followed by Stereotactic Ablative Radiotherapy Boost for Locally Advanced, Unresectable Non-Small Cell Lung Cancer: A Nonrandomized Controlled Trial. JAMA Oncol. 2024 Mar 01; 10(3):352-359.
Wu TC, Luterstein E, Neilsen BK, Goldman JW, Garon EB, Lee JM, Felix C, Cao M, Tenn SE, Low DA, Kupelian PA, Steinberg ML, Lee P. PMID: 38206614; PMCID: PMC10784998.
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PubMed Mentions:
2 Fields:
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Sleep Disturbance as a Mediator of Lung Cancer Stigma on Psychological Distress and Physical Symptom Burden. Psychosom Med. 2024 May 01; 86(4):334-341.
Williamson TJ, Garon EB, Irwin MR, Choi AK, Goldman JW, Stanton AL. PMID: 38436657; PMCID: PMC11081853.
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Translation:
Humans
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Safety profile of pembrolizumab monotherapy based on an aggregate safety evaluation of 8937 patients. Eur J Cancer. 2024 Mar; 199:113530.
Brahmer JR, Long GV, Hamid O, Garon EB, Herbst RS, Andre T, Armand P, Bajorin D, Bellmunt J, Burtness B, Choueiri TK, Cohen EEW, Diaz LA, Shitara K, Kulkarni G, McDermott D, Shah M, Tabernero J, Vogel A, Zinzani PL, Jafari N, Bird S, Snyder E, Gause C, Bracco OL, Pietanza MC, Gruber T, Ribas A. PMID: 38295556; PMCID: PMC11227881.
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PubMed Mentions:
7 Fields:
Translation:
Humans
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RELAY, Erlotinib Plus Ramucirumab in Untreated, EGFR-Mutated, Metastatic NSCLC: Outcomes by EGFR Exon 19 Deletion Variants. JTO Clin Res Rep. 2024 Feb; 5(2):100624.
Nishino K, Shih JY, Nakagawa K, Reck M, Garon EB, Carlsen M, Matsui T, Visseren-Grul C, Nadal E. PMID: 38304857; PMCID: PMC10832259.
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PubMed Mentions:
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Patient-reported outcomes with durvalumab, with or without tremelimumab, plus chemotherapy as first-line treatment for metastatic non-small-cell lung cancer (POSEIDON). Lung Cancer. 2023 12; 186:107422.
Garon EB, Cho BC, Luft A, Alatorre-Alexander J, Geater SL, Kim SW, Ursol G, Hussein M, Lim FL, Yang CT, Araujo LH, Saito H, Reinmuth N, Medic N, Mann H, Shi X, Peters S, Mok T, Johnson M. PMID: 37992595.
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PubMed Mentions:
2 Fields:
Translation:
Humans
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Understanding health-related quality of life measures used in early-stage non-small cell lung cancer clinical trials: A review. Lung Cancer. 2024 01; 187:107419.
Majem M, Basch E, Cella D, Garon EB, Herbst RS, Leighl NB. PMID: 38070301.
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PubMed Mentions:
1 Fields:
Translation:
Humans
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Bintrafusp Alfa With CCRT Followed by Bintrafusp Alfa Versus Placebo With CCRT Followed by Durvalumab in Patients With Unresectable Stage III NSCLC: A Phase 2 Randomized Study. J Thorac Oncol. 2024 02; 19(2):285-296.
Vokes EE, Mornex F, Sezer A, Cheng Y, Fang J, Baz DV, Cil T, Adjei AA, Ahn MJ, Barlesi F, Felip E, Garon EB, Audhuy F, Ito R, Sato M, Eggleton SP, Martin CM, Reck M, Robinson CG, Paz-Ares L. PMID: 37797733.
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PubMed Mentions:
4 Fields:
Translation:
HumansCTClinical Trials
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Canakinumab as Adjuvant Therapy in Patients With Completely Resected Non-Small-Cell Lung Cancer: Results From the CANOPY-A Double-Blind, Randomized Clinical Trial. J Clin Oncol. 2024 Jan 10; 42(2):180-191.
Garon EB, Lu S, Goto Y, De Marchi P, Paz-Ares L, Spigel DR, Thomas M, Yang JC, Ardizzoni A, Barlesi F, Orlov S, Yoshioka H, Mountzios G, Khanna S, Bossen C, Carbini M, Turri S, Myers A, Cho BC. PMID: 37788412.
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PubMed Mentions:
12 Fields:
Translation:
HumansCTClinical Trials
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Highlights in non-small cell lung cancer from the IASLC 2023 World Conference on Lung Cancer: commentary. Clin Adv Hematol Oncol. 2023 Oct; 21 Suppl 5(10):13-16.
Garon EB. PMID: 38307619.
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PubMed Mentions: Fields:
Translation:
Humans
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Clinical outcomes of ramucirumab plus docetaxel in the treatment of patients with non-small cell lung cancer after immunotherapy: a systematic literature review. Front Oncol. 2023; 13:1247879.
Garon EB, Visseren-Grul C, Rizzo MT, Puri T, Chenji S, Reck M. PMID: 37731641; PMCID: PMC10507469.
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PubMed Mentions:
3
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CCL21-DC in situ vaccination in murine NSCLC overcomes resistance to immunotherapy and generates systemic tumor-specific immunity. J Immunother Cancer. 2023 09; 11(9).
Salehi-Rad R, Lim RJ, Du Y, Tran LM, Li R, Ong SL, Ling Huang Z, Dumitras C, Zhang T, Park SJ, Crosson W, Kahangi B, Abascal J, Seet C, Oh M, Shabihkhani M, Paul M, Krysan K, Lisberg AE, Garon EB, Liu B, Dubinett SM. PMID: 37730274; PMCID: PMC10510892.
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PubMed Mentions:
3 Fields:
Translation:
HumansAnimals
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Bintrafusp Alfa Versus Pembrolizumab in Patients With Treatment-Naive, Programmed Death-Ligand 1-High Advanced NSCLC: A Randomized, Open-Label, Phase 3 Trial. J Thorac Oncol. 2023 12; 18(12):1731-1742.
Cho BC, Lee JS, Wu YL, Cicin I, Dols MC, Ahn MJ, Cuppens K, Veillon R, Nadal E, Dias JM, Martin C, Reck M, Garon EB, Felip E, Paz-Ares L, Mornex F, Vokes EE, Adjei AA, Robinson C, Sato M, Vugmeyster Y, Machl A, Audhuy F, Chaudhary S, Barlesi F. PMID: 37597750.
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PubMed Mentions:
17 Fields:
Translation:
HumansCTClinical Trials
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Consent document translation expense hinders inclusive clinical trial enrolment. Nature. 2023 Aug; 620(7975):855-862.
Velez MA, Glenn BA, Garcia-Jimenez M, Cummings AL, Lisberg A, Nañez A, Radwan Y, Lind-Lebuffe JP, Brodrick PM, Li DY, Fernandez-Turizo MJ, Gower A, Lindenbaum M, Hegde M, Brook J, Grogan T, Elashoff D, Teitell MA, Garon EB. PMID: 37532930; PMCID: PMC11046417.
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PubMed Mentions:
1 Fields:
Translation:
Humans
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Corrigendum to "Safety of pemetrexed plus platinum in combination with pembrolizumab for metastatic nonsquamous non-small cell lung cancer: A post hoc analysis of KEYNOTE-189" [Lung Cancer 155 (2021) 53-60]. Lung Cancer. 2023 Sep; 183:107285.
Garon EB, Aerts J, Kim JS, Muehlenbein CE, Peterson P, Rizzo MT, Gadgeel SM. PMID: 37460344.
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PubMed Mentions: Fields:
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Biomarker-directed, pembrolizumab-based combination therapy in non-small cell lung cancer: phase 2 KEYNOTE-495/KeyImPaCT trial interim results. Nat Med. 2023 07; 29(7):1718-1727.
Gutierrez M, Lam WS, Hellmann MD, Gubens MA, Aggarwal C, Tan DSW, Felip E, Chiu JWY, Lee JS, Yang JC, Garon EB, Finocchiaro G, Ahn MJ, Luft A, Landers GA, Basso A, Ma H, Kobie J, Palcza J, Cristescu R, Fong L, Snyder A, Yuan J, Herbst RS. PMID: 37429923.
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PubMed Mentions:
10 Fields:
Translation:
HumansCTClinical Trials
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Comprehensive tissue deconvolution of cell-free DNA by deep learning for disease diagnosis and monitoring. Proc Natl Acad Sci U S A. 2023 07 11; 120(28):e2305236120.
Li S, Zeng W, Ni X, Liu Q, Li W, Stackpole ML, Zhou Y, Gower A, Krysan K, Ahuja P, Lu DS, Raman SS, Hsu W, Aberle DR, Magyar CE, French SW, Han SB, Garon EB, Agopian VG, Wong WH, Dubinett SM, Zhou XJ. PMID: 37399400; PMCID: PMC10334733.
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PubMed Mentions:
13 Fields:
Translation:
HumansCells
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Ramucirumab plus erlotinib versus placebo plus erlotinib in previously untreated EGFR-mutated metastatic non-small-cell lung cancer (RELAY): exploratory analysis of next-generation sequencing results. ESMO Open. 2023 08; 8(4):101580.
Garon EB, Reck M, Nishio K, Heymach JV, Nishio M, Novello S, Paz-Ares L, Popat S, Aix SP, Graham H, Butts BD, Visseren-Grul C, Nakagawa K, RELAY study investigators. PMID: 37390764; PMCID: PMC10485403.
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PubMed Mentions:
8 Translation:
Humans
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First-in-Human, Phase I Dose-Escalation and Dose-Expansion Study of Trophoblast Cell-Surface Antigen 2-Directed Antibody-Drug Conjugate Datopotamab Deruxtecan in Non-Small-Cell Lung Cancer: TROPION-PanTumor01. J Clin Oncol. 2023 10 10; 41(29):4678-4687.
Shimizu T, Sands J, Yoh K, Spira A, Garon EB, Kitazono S, Johnson ML, Meric-Bernstam F, Tolcher AW, Yamamoto N, Greenberg J, Kawasaki Y, Zebger-Gong H, Kobayashi F, Phillips P, Lisberg AE, Heist RS. PMID: 37327461; PMCID: PMC10564307.
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PubMed Mentions:
21 Fields:
Translation:
HumansCellsCTClinical Trials
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Brief Report: Safety and Antitumor Activity of Durvalumab Plus Tremelimumab in Programmed Cell Death-(Ligand)1-Monotherapy Pretreated, Advanced NSCLC: Results From a Phase 1b Clinical Trial. J Thorac Oncol. 2023 08; 18(8):1094-1102.
Garon EB, Spira AI, Goldberg SB, Chaft JE, Papadimitrakopoulou V, Cascone T, Antonia SJ, Brahmer JR, Camidge DR, Powderly JD, Wozniak AJ, Felip E, Wu S, Ascierto ML, Elgeioushi N, Awad MM. PMID: 37146752.
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PubMed Mentions: Fields:
Translation:
HumansCTClinical Trials
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Safety and Efficacy Results From iSABR, a Phase 1 Study of Stereotactic ABlative Radiotherapy in Combination With Durvalumab for Early-Stage Medically Inoperable Non-Small Cell Lung Cancer. Int J Radiat Oncol Biol Phys. 2023 09 01; 117(1):118-122.
Wu TC, Stube A, Felix C, Oseguera D, Romero T, Goldman J, Garon EB, Lee JM, Glaspy J, Lisberg AE, Rusthoven CG, Camidge DR, Siva S, Solomon B, Lee A, Tenn SE, Shaverdian N, Steinberg ML, Raldow AC, Lee P. PMID: 37023987.
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PubMed Mentions:
6 Fields:
Translation:
HumansCTClinical Trials
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RELAY, Ramucirumab Plus Erlotinib (RAM+ERL) in Untreated Metastatic EGFR-Mutant NSCLC (EGFR+ NSCLC): Association Between TP53 Status and Clinical Outcome. Clin Lung Cancer. 2023 07; 24(5):415-428.
Nishio M, Paz-Ares L, Reck M, Nakagawa K, Garon EB, Popat S, Ceccarelli M, Graham HT, Visseren-Grul C, Novello S. PMID: 37076395.
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PubMed Mentions:
11 Fields:
Translation:
HumansCTClinical Trials
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MRTX-500 Phase 2 Trial: Sitravatinib With Nivolumab in Patients With Nonsquamous NSCLC Progressing On or After Checkpoint Inhibitor Therapy or Chemotherapy. J Thorac Oncol. 2023 07; 18(7):907-921.
He K, Berz D, Gadgeel SM, Iams WT, Bruno DS, Blakely CM, Spira AI, Patel MR, Waterhouse DM, Richards DA, Pham A, Jotte R, Hong DS, Garon EB, Traynor A, Olson P, Latven L, Yan X, Shazer R, Leal TA. PMID: 36842467; PMCID: PMC10330304.
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PubMed Mentions:
9 Fields:
Translation:
HumansCTClinical Trials
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Pembrolizumab Plus Pemetrexed and Platinum in Nonsquamous Non-Small-Cell Lung Cancer: 5-Year Outcomes From the Phase 3 KEYNOTE-189 Study. J Clin Oncol. 2023 04 10; 41(11):1992-1998.
Garassino MC, Gadgeel S, Speranza G, Felip E, Esteban E, Dómine M, Hochmair MJ, Powell SF, Bischoff HG, Peled N, Grossi F, Jennens RR, Reck M, Hui R, Garon EB, Kurata T, Gray JE, Schwarzenberger P, Jensen E, Pietanza MC, Rodríguez-Abreu D. PMID: 36809080; PMCID: PMC10082311.
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PubMed Mentions:
127 Fields:
Translation:
Humans
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Is There a Place for Temozolomide plus Nivolumab among Neuroendocrine Neoplasms? Clin Cancer Res. 2023 02 16; 29(4):691-693.
Velez MA, Garon EB. PMID: 36520037.
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PubMed Mentions: Fields:
Translation:
Humans
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Mocetinostat in Combination With Durvalumab for Patients With Advanced NSCLC: Results From a Phase I/II Study. Clin Lung Cancer. 2023 05; 24(3):218-227.
Johnson ML, Strauss J, Patel MR, Garon EB, Eaton KD, Neskorik T, Morin J, Chao R, Halmos B. PMID: 36890020.
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PubMed Mentions:
2 Fields:
Translation:
HumansCTClinical Trials
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View in:
PubMed Mentions:
2
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Patient-reported outcomes in capmatinib-treated patients with METex14-mutated advanced NSCLC: Results from the GEOMETRY mono-1 study. Eur J Cancer. 2023 04; 183:98-108.
Wolf J, Garon EB, Groen HJM, Tan DSW, Gilloteau I, Le Mouhaer S, Hampe M, Cai C, Chassot-Agostinho A, Reynolds M, Sherif B, Heist RS. PMID: 36822130.
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PubMed Mentions:
4 Fields:
Translation:
Humans
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Pembrolizumab in advanced non-small cell lung cancer: safety implications of dose adjustments. Transl Cancer Res. 2022 Dec; 11(12):4479-4481.
Gower A, Garon EB. PMID: 36644181; PMCID: PMC9834586.
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PubMed Mentions:
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Mass Cytometry Reveals Classical Monocytes, NK Cells, and ICOS+ CD4+ T Cells Associated with Pembrolizumab Efficacy in Patients with Lung Cancer. Clin Cancer Res. 2022 12 01; 28(23):5136-5148.
Rochigneux P, Lisberg A, Garcia A, Granjeaud S, Madroszyk A, Fattori S, Gonçalves A, Devillier R, Maby P, Salem N, Gorvel L, Chanez B, Gukasyan J, Carroll J, Goldman J, Chretien AS, Olive D, Garon EB. PMID: 36166003; PMCID: PMC10085054.
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PubMed Mentions:
12 Fields:
Translation:
HumansCells
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Associations of Tissue Tumor Mutational Burden and Mutational Status With Clinical Outcomes With Pembrolizumab Plus Chemotherapy Versus Chemotherapy For Metastatic NSCLC. JTO Clin Res Rep. 2023 Jan; 4(1):100431.
Garassino MC, Gadgeel S, Novello S, Halmos B, Felip E, Speranza G, Hui R, Garon EB, Horinouchi H, Sugawara S, Rodriguez-Abreu D, Reck M, Cristescu R, Aurora-Garg D, Loboda A, Lunceford J, Kobie J, Ayers M, Piperdi B, Pietanza MC, Paz-Ares L. PMID: 36793385; PMCID: PMC9923193.
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PubMed Mentions:
14
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Durvalumab With or Without Tremelimumab in Combination With Chemotherapy as First-Line Therapy for Metastatic Non-Small-Cell Lung Cancer: The Phase III POSEIDON Study. J Clin Oncol. 2023 02 20; 41(6):1213-1227.
Johnson ML, Cho BC, Luft A, Alatorre-Alexander J, Geater SL, Laktionov K, Kim SW, Ursol G, Hussein M, Lim FL, Yang CT, Araujo LH, Saito H, Reinmuth N, Shi X, Poole L, Peters S, Garon EB, Mok T, POSEIDON investigators. PMID: 36327426; PMCID: PMC9937097.
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PubMed Mentions:
106 Fields:
Translation:
Humans
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Surgical results of the Lung Cancer Mutation Consortium 3 trial: A phase II multicenter single-arm study to investigate the efficacy and safety of atezolizumab as neoadjuvant therapy in patients with stages IB-select IIIB resectable non-small cell lung cancer. J Thorac Cardiovasc Surg. 2023 03; 165(3):828-839.e5.
Rusch VW, Nicholas A, Patterson GA, Waqar SN, Toloza EM, Haura EB, Raz DJ, Reckamp KL, Merritt RE, Owen DH, Finley DJ, McNamee CJ, Blasberg JD, Garon EB, Mitchell JD, Doebele RC, Baciewicz F, Nagasaka M, Pass HI, Schulze K, Johnson A, Bunn PA, Johnson BE, Kris MG, Kwiatkowski DJ, Wistuba II, Chaft JE, Carbone DP, Lee JM. PMID: 36369159; PMCID: PMC10288861.
View in:
PubMed Mentions:
5 Fields:
Translation:
HumansCTClinical Trials
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Cost-effective methylome sequencing of cell-free DNA for accurately detecting and locating cancer. Nat Commun. 2022 09 29; 13(1):5566.
Stackpole ML, Zeng W, Li S, Liu CC, Zhou Y, He S, Yeh A, Wang Z, Sun F, Li Q, Yuan Z, Yildirim A, Chen PJ, Winograd P, Tran B, Lee YT, Li PS, Noor Z, Yokomizo M, Ahuja P, Zhu Y, Tseng HR, Tomlinson JS, Garon E, French S, Magyar CE, Dry S, Lajonchere C, Geschwind D, Choi G, Saab S, Alber F, Wong WH, Dubinett SM, Aberle DR, Agopian V, Han SB, Ni X, Li W, Zhou XJ. PMID: 36175411; PMCID: PMC9522828.
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PubMed Mentions:
28 Fields:
Translation:
Humans
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Personalized neoantigen vaccine NEO-PV-01 with chemotherapy and anti-PD-1 as first-line treatment for non-squamous non-small cell lung cancer. Cancer Cell. 2022 09 12; 40(9):1010-1026.e11.
Awad MM, Govindan R, Balogh KN, Spigel DR, Garon EB, Bushway ME, Poran A, Sheen JH, Kohler V, Esaulova E, Srouji J, Ramesh S, Vyasamneni R, Karki B, Sciuto TE, Sethi H, Dong JZ, Moles MA, Manson K, Rooney MS, Khondker ZS, DeMario M, Gaynor RB, Srinivasan L. PMID: 36027916.
View in:
PubMed Mentions:
64 Fields:
Translation:
HumansCellsCTClinical Trials
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Comparison of the tumor immune microenvironment and checkpoint blockade biomarkers between stage III and IV non-small cell lung cancer. Cancer Immunol Immunother. 2023 Feb; 72(2):339-350.
Gao Y, Stein MM, Kase M, Cummings AL, Bharanikumar R, Lau D, Garon EB, Patel SP. PMID: 35881197; PMCID: PMC9870967.
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PubMed Mentions:
5 Fields:
Translation:
Humans
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RELAY, ramucirumab plus erlotinib versus placebo plus erlotinib in untreated EGFR-mutated metastatic non-small cell lung cancer: exposure-response relationship. Cancer Chemother Pharmacol. 2022 08; 90(2):137-148.
Nakagawa K, Garon EB, Gao L, Callies S, Zimmermann A, Walgren R, Visseren-Grul C, Reck M. PMID: 35841410; PMCID: PMC9360106.
View in:
PubMed Mentions:
2 Fields:
Translation:
Humans
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Targeting EZH2 to overcome the resistance to immunotherapy in lung cancer. Semin Oncol. 2022 Jun; 49(3-4):306-318.
Shin DS, Park K, Garon E, Dubinett S. PMID: 35851153.
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PubMed Mentions:
5 Fields:
-
cfTrack: A Method of Exome-Wide Mutation Analysis of Cell-free DNA to Simultaneously Monitor the Full Spectrum of Cancer Treatment Outcomes Including MRD, Recurrence, and Evolution. Clin Cancer Res. 2022 05 02; 28(9):1841-1853.
Li S, Zeng W, Ni X, Zhou Y, Stackpole ML, Noor ZS, Yuan Z, Neal A, Memarzadeh S, Garon EB, Dubinett SM, Li W, Zhou XJ. PMID: 35149536; PMCID: PMC9126584.
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PubMed Mentions:
4 Fields:
Translation:
Humans
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Society for Immunotherapy of Cancer (SITC) clinical practice guideline on immunotherapy for the treatment of lung cancer and mesothelioma. J Immunother Cancer. 2022 05; 10(5).
Govindan R, Aggarwal C, Antonia SJ, Davies M, Dubinett SM, Ferris A, Forde PM, Garon EB, Goldberg SB, Hassan R, Hellmann MD, Hirsch FR, Johnson ML, Malik S, Morgensztern D, Neal JW, Patel JD, Rimm DL, Sagorsky S, Schwartz LH, Sepesi B, Herbst RS. PMID: 35640927; PMCID: PMC9157337.
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PubMed Mentions:
14 Fields:
Translation:
Humans
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Facets of stigma, self-compassion, and health-related adjustment to lung cancer: A longitudinal study. Health Psychol. 2022 Apr; 41(4):301-310.
Williamson TJ, Garon EB, Shapiro JR, Chavira DA, Goldman JW, Stanton AL. PMID: 35324247; PMCID: PMC9030259.
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PubMed Mentions:
6 Fields:
Translation:
Humans
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ANtiangiogenic Second-line Lung cancer Meta-Analysis on individual patient data in non-small cell lung cancer: ANSELMA. Eur J Cancer. 2022 05; 166:112-125.
Remon J, Lacas B, Herbst R, Reck M, Garon EB, Scagliotti GV, Ramlau R, Hanna N, Vansteenkiste J, Yoh K, Groen HJM, Heymach JV, Mandrekar SJ, Okamoto I, Neal JW, Heist RS, Planchard D, Pignon JP, Besse B, ANSELMA collaborative group. PMID: 35286903.
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PubMed Mentions:
2 Fields:
Translation:
Humans
-
RELAY+: Exploratory Study of Ramucirumab Plus Gefitinib in Untreated Patients With EGFR-Mutated Metastatic NSCLC. JTO Clin Res Rep. 2022 Apr; 3(4):100303.
Nishio M, Nishio K, Reck M, Garon EB, Imamura F, Kawaguchi T, Yamaguchi H, Ikeda S, Hirano K, Visseren-Grul C, Ceccarelli M, Wijayawardana SR, Zimmermann A, Matsui T, Enatsu S, Nakagawa K. PMID: 35369607; PMCID: PMC8966141.
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PubMed Mentions:
1
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What is the current role of immunotherapy in EGFR mutant advanced NSCLC? Lung Cancer. 2022 04; 166:253-254.
Velez MA, Tsai HHC, Shackelford DB, Garon EB, Lisberg A. PMID: 35031176.
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PubMed Mentions: Fields:
Translation:
Humans
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RELAY, Ramucirumab Plus Erlotinib Versus Placebo Plus Erlotinib in Patients with Untreated, Epidermal Growth Factor Receptor Mutation-Positive, Metastatic Non-Small-Cell Lung Cancer: Safety Profile and Manageability. Drug Saf. 2022 01; 45(1):45-64.
Nadal E, Horinouchi H, Shih JY, Nakagawa K, Reck M, Garon EB, Wei YF, Kollmeier J, Frimodt-Moller B, Barrett E, Lipkovich O, Visseren-Grul C, Novello S. PMID: 34928484; PMCID: PMC8763844.
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PubMed Mentions:
4 Fields:
Translation:
Humans
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Defining comprehensive biomarker-related testing and treatment practices for advanced non-small-cell lung cancer: Results of a survey of U.S. oncologists. Cancer Med. 2022 01; 11(2):530-538.
Mileham KF, Schenkel C, Bruinooge SS, Freeman-Daily J, Basu Roy U, Moore A, Smith RA, Garrett-Mayer E, Rosenthal L, Garon EB, Johnson BE, Osarogiagbon RU, Jalal S, Virani S, Weber Redman M, Silvestri GA. PMID: 34921524; PMCID: PMC8729042.
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PubMed Mentions:
18 Fields:
Translation:
Humans
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Targeting more precisely: Improving sensitivity to EGFR inhibitors in NSCLC. Med. 2021 11 12; 2(11):1201-1202.
Gower A, Garon EB. PMID: 35590196.
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PubMed Mentions:
1 Fields:
Translation:
Humans
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Overall Survival and Safety With Pemetrexed/Platinum ± Anti-VEGF Followed by Pemetrexed ± Anti-VEGF Maintenance in Advanced Nonsquamous Non-Small-Cell Lung Cancer: A Pooled Analysis of 4 Randomized Studies. Clin Lung Cancer. 2022 May; 23(3):253-263.
Garon EB, Peterson P, Rizzo MT, Kim JS. PMID: 34852947.
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PubMed Mentions: Fields:
Translation:
Humans
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Technical Feasibility and Safety of Repeated Computed Tomography-Guided Transthoracic Intratumoral Injection of Gene-Modified Cellular Immunotherapy in Metastatic NSCLC. JTO Clin Res Rep. 2021 Nov; 2(11):100242.
Shahrouki P, Lee JM, Barclay J, Khan SN, Genshaft S, Abtin F, Dubinett SM, Lisberg A, Sharma S, Garon EB, Suh R. PMID: 34806054; PMCID: PMC8581369.
View in:
PubMed Mentions:
1
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RELAY Subgroup Analyses by EGFR Ex19del and Ex21L858R Mutations for Ramucirumab Plus Erlotinib in Metastatic Non-Small Cell Lung Cancer. Clin Cancer Res. 2021 10 01; 27(19):5258-5271.
Nakagawa K, Nadal E, Garon EB, Nishio M, Seto T, Yamamoto N, Park K, Shih JY, Paz-Ares L, Frimodt-Moller B, Zimmermann AH, Wijayawardana S, Visseren-Grul C, Reck M. PMID: 34301751; PMCID: PMC9662911.
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PubMed Mentions:
23 Fields:
Translation:
Humans
-
Immune checkpoint inhibitor induced thyroid dysfunction is a frequent event post-treatment in NSCLC. Lung Cancer. 2021 11; 161:34-41.
Zhou N, Velez MA, Bachrach B, Gukasyan J, Fares CM, Cummings AL, Lind-Lebuffe JP, Akingbemi WO, Li DY, Brodrick PM, Yessuf NM, Rettinger S, Grogan T, Rochigneux P, Goldman JW, Garon EB, Lisberg A. PMID: 34507111; PMCID: PMC8923054.
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PubMed Mentions:
6 Fields:
Translation:
Humans
-
Sensitive detection of tumor mutations from blood and its application to immunotherapy prognosis. Nat Commun. 2021 07 07; 12(1):4172.
Li S, Noor ZS, Zeng W, Stackpole ML, Ni X, Zhou Y, Yuan Z, Wong WH, Agopian VG, Dubinett SM, Alber F, Li W, Garon EB, Zhou XJ. PMID: 34234141; PMCID: PMC8263778.
View in:
PubMed Mentions:
15 Fields:
Translation:
HumansCTClinical Trials
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Outcomes With Pembrolizumab Monotherapy in Patients With Programmed Death-Ligand 1-Positive NSCLC With Brain Metastases: Pooled Analysis of KEYNOTE-001, 010, 024, and 042. JTO Clin Res Rep. 2021 Aug; 2(8):100205.
Mansfield AS, Herbst RS, de Castro G, Hui R, Peled N, Kim DW, Novello S, Satouchi M, Wu YL, Garon EB, Reck M, Robinson AG, Samkari A, Piperdi B, Ebiana V, Lin J, Mok TSK. PMID: 34590048; PMCID: PMC8474394.
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PubMed Mentions:
37
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A Phase Ib Open-Label, Multicenter Study of Inhaled DV281, a TLR9 Agonist, in Combination with Nivolumab in Patients with Advanced or Metastatic Non-small Cell Lung Cancer. Clin Cancer Res. 2021 08 15; 27(16):4566-4573.
Garon EB, Spira AI, Johnson M, Bazhenova L, Leach J, Cummings AL, Candia A, Coffman RL, Janatpour MJ, Janssen R, Gamelin E, Chow LQM. PMID: 34108179.
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PubMed Mentions:
9 Fields:
Translation:
HumansCTClinical Trials
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Five Year Survival Update From KEYNOTE-010: Pembrolizumab Versus Docetaxel for Previously Treated, Programmed Death-Ligand 1-Positive Advanced NSCLC. J Thorac Oncol. 2021 10; 16(10):1718-1732.
Herbst RS, Garon EB, Kim DW, Cho BC, Gervais R, Perez-Gracia JL, Han JY, Majem M, Forster MD, Monnet I, Novello S, Gubens MA, Boyer M, Su WC, Samkari A, Jensen EH, Kobie J, Piperdi B, Baas P. PMID: 34048946.
View in:
PubMed Mentions:
118 Fields:
Translation:
Humans
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Ramucirumab Plus Erlotinib Versus Placebo Plus Erlotinib in Patients With Untreated Metastatic EGFR-Mutated NSCLC: RELAY Japanese Subset. JTO Clin Res Rep. 2021 Jun; 2(6):100171.
Nishio K, Seto T, Nishio M, Reck M, Garon EB, Sakai K, Goto K, Kato T, Nakanishi Y, Takahashi T, Yamamoto N, Kiura K, Ohe Y, Tamura T, Visseren-Grul C, Frimodt-Moller B, Hozak RR, Wijayawardana SR, Zimmermann A, Homma G, Enatsu S, Nakagawa K. PMID: 34590023; PMCID: PMC8474372.
View in:
PubMed Mentions:
6
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Severity of COVID-19 in patients with lung cancer: evidence and challenges. J Immunother Cancer. 2021 03; 9(3).
Passaro A, Bestvina C, Velez Velez M, Garassino MC, Garon E, Peters S. PMID: 33737345; PMCID: PMC7978268.
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PubMed Mentions:
57 Fields:
Translation:
HumansCells
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Targeted Therapy Approaches for MET Abnormalities in Non-Small Cell Lung Cancer. Drugs. 2021 Apr; 81(5):547-554.
Garon EB, Brodrick P. PMID: 33638808.
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PubMed Mentions:
11 Fields:
Translation:
Humans
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Safety of pemetrexed plus platinum in combination with pembrolizumab for metastatic nonsquamous non-small cell lung cancer: A post hoc analysis of KEYNOTE-189. Lung Cancer. 2021 05; 155:53-60.
Garon EB, Aerts J, Kim JS, Muehlenbein CE, Peterson P, Rizzo MT, Gadgeel SM. PMID: 33730652.
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PubMed Mentions:
5 Fields:
Translation:
Humans
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Patient-Reported Outcomes with Durvalumab With or Without Tremelimumab Versus Standard Chemotherapy as First-Line Treatment of Metastatic Non-Small-Cell Lung Cancer (MYSTIC). Clin Lung Cancer. 2021 07; 22(4):301-312.e8.
Garon EB, Cho BC, Reinmuth N, Lee KH, Luft A, Ahn MJ, Robinet G, Le Moulec S, Natale R, Schneider J, Shepherd FA, Garassino MC, Geater SL, Szekely ZP, Van Ngoc T, Liu F, Scheuring U, Patel N, Peters S, Rizvi NA. PMID: 33775558.
View in:
PubMed Mentions:
9 Fields:
Translation:
HumansCTClinical Trials
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Investigation of Combination Treatment With an Aromatase Inhibitor Exemestane and Carboplatin-Based Therapy for Postmenopausal Women With Advanced NSCLC. JTO Clin Res Rep. 2021 Apr; 2(4):100150.
Young PA, Márquez-Garbán DC, Noor ZS, Moatamed N, Elashoff D, Grogan T, Romero T, Sasano H, Saito R, Rausch R, Hamilton N, Dubinett SM, Garon EB, Pietras RJ. PMID: 34590007; PMCID: PMC8474426.
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PubMed Mentions:
3
-
Osimertinib plus Ramucirumab: The Best of Both Worlds? Clin Cancer Res. 2021 02 15; 27(4):905-907.
Garon EB. PMID: 33334907; PMCID: PMC7887048.
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PubMed Mentions: Fields:
Translation:
Humans
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Pemetrexed maintenance with or without pembrolizumab in non-squamous non-small cell lung cancer: A cross-trial comparison of KEYNOTE-189 versus PARAMOUNT, PRONOUNCE, and JVBL. Lung Cancer. 2021 01; 151:25-29.
Garon EB, Kim JS, Govindan R. PMID: 33285468.
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PubMed Mentions:
3 Fields:
Translation:
Humans
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Mutational landscape influences immunotherapy outcomes among patients with non-small-cell lung cancer with human leukocyte antigen supertype B44. Nat Cancer. 2020 12; 1(12):1167-1175.
Cummings AL, Gukasyan J, Lu HY, Grogan T, Sunga G, Fares CM, Hornstein N, Zaretsky J, Carroll J, Bachrach B, Akingbemi WO, Li D, Noor Z, Lisberg A, Goldman JW, Elashoff D, Bui AAT, Ribas A, Dubinett SM, Rossetti M, Garon EB. PMID: 35121931.
View in:
PubMed Mentions:
18 Fields:
Translation:
Humans
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What Is on the Horizon for Novel Immunotherapies in Lung Cancer? Cancer J. 2020 Nov/Dec; 26(6):555-560.
Garon EB, Li DY. PMID: 33298728.
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PubMed Mentions: Fields:
Translation:
Humans
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Dual EGFR-VEGF Pathway Inhibition: A Promising Strategy for Patients With EGFR-Mutant NSCLC. J Thorac Oncol. 2021 02; 16(2):205-215.
Le X, Nilsson M, Goldman J, Reck M, Nakagawa K, Kato T, Ares LP, Frimodt-Moller B, Wolff K, Visseren-Grul C, Heymach JV, Garon EB. PMID: 33096270.
View in:
PubMed Mentions:
111 Fields:
Translation:
Humans
-
Ramucirumab or placebo plus erlotinib in EGFR-mutated, metastatic non-small-cell lung cancer: East Asian subset of RELAY. Cancer Sci. 2020 Dec; 111(12):4510-4525.
Nishio M, Seto T, Reck M, Garon EB, Chiu CH, Yoh K, Imamura F, Park K, Shih JY, Visseren-Grul C, Frimodt-Moller B, Zimmermann A, Homma G, Enatsu S, Nakagawa K, RELAY Study Investigators. PMID: 32954593; PMCID: PMC7734014.
View in:
PubMed Mentions:
15 Fields:
Translation:
HumansCTClinical Trials
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Detection of EGFR Mutations in cfDNA and CTCs, and Comparison to Tumor Tissue in Non-Small-Cell-Lung-Cancer (NSCLC) Patients. Front Oncol. 2020; 10:572895.
Liu HE, Vuppalapaty M, Wilkerson C, Renier C, Chiu M, Lemaire C, Che J, Matsumoto M, Carroll J, Crouse S, Hanft VR, Jeffrey SS, Di Carlo D, Garon EB, Goldman J, Sollier E. PMID: 33117705; PMCID: PMC7578230.
View in:
PubMed Mentions:
27
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Continuous Versus 1-Year Fixed-Duration Nivolumab in Previously Treated Advanced Non-Small-Cell Lung Cancer: CheckMate 153. J Clin Oncol. 2020 11 20; 38(33):3863-3873.
Waterhouse DM, Garon EB, Chandler J, McCleod M, Hussein M, Jotte R, Horn L, Daniel DB, Keogh G, Creelan B, Einhorn LH, Baker J, Kasbari S, Nikolinakos P, Babu S, Couture F, Leighl NB, Reynolds C, Blumenschein G, Gunuganti V, Li A, Aanur N, Spigel DR. PMID: 32910710; PMCID: PMC7676888.
View in:
PubMed Mentions:
82 Fields:
Translation:
HumansCTClinical Trials
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Capmatinib in MET Exon 14-Mutated or MET-Amplified Non-Small-Cell Lung Cancer. N Engl J Med. 2020 09 03; 383(10):944-957.
Wolf J, Seto T, Han JY, Reguart N, Garon EB, Groen HJM, Tan DSW, Hida T, de Jonge M, Orlov SV, Smit EF, Souquet PJ, Vansteenkiste J, Hochmair M, Felip E, Nishio M, Thomas M, Ohashi K, Toyozawa R, Overbeck TR, de Marinis F, Kim TM, Laack E, Robeva A, Le Mouhaer S, Waldron-Lynch M, Sankaran B, Balbin OA, Cui X, Giovannini M, Akimov M, Heist RS, GEOMETRY mono-1 Investigators. PMID: 32877583.
View in:
PubMed Mentions:
383 Fields:
Translation:
HumansCTClinical Trials
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Patient-reported outcomes in RELAY, a phase 3 trial of ramucirumab plus erlotinib versus placebo plus erlotinib in untreated EGFR-mutated metastatic non-small-cell lung cancer. Curr Med Res Opin. 2020 10; 36(10):1667-1675.
Yoh K, Atagi S, Reck M, Garon EB, Ponce Aix S, Moro-Sibilot D, Winfree KB, Frimodt-Moller B, Zimmermann A, Visseren-Grul C, Nakagawa K, RELAY investigators. PMID: 32780643.
View in:
PubMed Mentions:
3 Fields:
Translation:
HumansCTClinical Trials
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Medical Treatment of Lung Cancer: Can Immune Cells Predict the Response? A Systematic Review. Front Immunol. 2020; 11:1036.
Rochigneux P, Garcia AJ, Chanez B, Madroszyk A, Olive D, Garon EB. PMID: 32670271; PMCID: PMC7327092.
View in:
PubMed Mentions:
9 Fields:
Translation:
Humans
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Is there hope in improving 5-year overall survival?-review of 5-year overall survival data from KEYNOTE-001. Ann Transl Med. 2020 Jun; 8(11):728.
Akingbemi W, Garon E. PMID: 32617347; PMCID: PMC7327376.
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PubMed Mentions:
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Durvalumab With or Without Tremelimumab vs Standard Chemotherapy in First-line Treatment of Metastatic Non-Small Cell Lung Cancer: The MYSTIC Phase 3 Randomized Clinical Trial. JAMA Oncol. 2020 05 01; 6(5):661-674.
Rizvi NA, Cho BC, Reinmuth N, Lee KH, Luft A, Ahn MJ, van den Heuvel MM, Cobo M, Vicente D, Smolin A, Moiseyenko V, Antonia SJ, Le Moulec S, Robinet G, Natale R, Schneider J, Shepherd FA, Geater SL, Garon EB, Kim ES, Goldberg SB, Nakagawa K, Raja R, Higgs BW, Boothman AM, Zhao L, Scheuring U, Stockman PK, Chand VK, Peters S, MYSTIC Investigators. PMID: 32271377; PMCID: PMC7146551.
View in:
PubMed Mentions:
287 Fields:
Translation:
HumansCTClinical Trials
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Healthcare resource utilization in advanced non-small-cell lung cancer: post hoc analysis of the randomized phase 3 REVEL study. Support Care Cancer. 2021 Jan; 29(1):117-125.
Garon EB, Winfree KB, Molife C, Cui ZL, Arriola E, Levy B, Mekhail T, Pérol M. PMID: 32318871; PMCID: PMC7686169.
View in:
PubMed Mentions:
2 Fields:
Translation:
Humans
-
Immune Checkpoint Inhibitors in Thoracic Malignancies: Review of the Existing Evidence by an IASLC Expert Panel and Recommendations. J Thorac Oncol. 2020 06; 15(6):914-947.
Remon J, Passiglia F, Ahn MJ, Barlesi F, Forde PM, Garon EB, Gettinger S, Goldberg SB, Herbst RS, Horn L, Kubota K, Lu S, Mezquita L, Paz-Ares L, Popat S, Schalper KA, Skoulidis F, Reck M, Adjei AA, Scagliotti GV. PMID: 32179179.
View in:
PubMed Mentions:
92 Fields:
Translation:
Humans
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Updated Analysis From KEYNOTE-189: Pembrolizumab or Placebo Plus Pemetrexed and Platinum for Previously Untreated Metastatic Nonsquamous Non-Small-Cell Lung Cancer. J Clin Oncol. 2020 05 10; 38(14):1505-1517.
Gadgeel S, Rodríguez-Abreu D, Speranza G, Esteban E, Felip E, Dómine M, Hui R, Hochmair MJ, Clingan P, Powell SF, Cheng SY, Bischoff HG, Peled N, Grossi F, Jennens RR, Reck M, Garon EB, Novello S, Rubio-Viqueira B, Boyer M, Kurata T, Gray JE, Yang J, Bas T, Pietanza MC, Garassino MC. PMID: 32150489.
View in:
PubMed Mentions:
475 Fields:
Translation:
Humans
-
Long-Term Outcomes and Retreatment Among Patients With Previously Treated, Programmed Death-Ligand 1‒Positive, Advanced Non‒Small-Cell Lung Cancer in the KEYNOTE-010 Study. J Clin Oncol. 2020 05 10; 38(14):1580-1590.
Herbst RS, Garon EB, Kim DW, Cho BC, Perez-Gracia JL, Han JY, Arvis CD, Majem M, Forster MD, Monnet I, Novello S, Szalai Z, Gubens MA, Su WC, Ceresoli GL, Samkari A, Jensen EH, Lubiniecki GM, Baas P. PMID: 32078391.
View in:
PubMed Mentions:
121 Fields:
Translation:
Humans
-
The Role of Interleukin 1β in the Pathogenesis of Lung Cancer. JTO Clin Res Rep. 2020 Mar; 1(1):100001.
Garon EB, Chih-Hsin Yang J, Dubinett SM. PMID: 34589908; PMCID: PMC8474414.
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PubMed Mentions:
29
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Patient-reported outcomes following pembrolizumab or placebo plus pemetrexed and platinum in patients with previously untreated, metastatic, non-squamous non-small-cell lung cancer (KEYNOTE-189): a multicentre, double-blind, randomised, placebo-controlled, phase 3 trial. Lancet Oncol. 2020 03; 21(3):387-397.
Garassino MC, Gadgeel S, Esteban E, Felip E, Speranza G, Domine M, Hochmair MJ, Powell S, Cheng SY, Bischoff HG, Peled N, Reck M, Hui R, Garon EB, Boyer M, Wei Z, Burke T, Pietanza MC, Rodríguez-Abreu D. PMID: 32035514.
View in:
PubMed Mentions:
88 Fields:
Translation:
HumansCTClinical Trials
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Exploratory analysis of front-line therapies in REVEL: a randomised phase 3 study of ramucirumab plus docetaxel versus docetaxel for the treatment of stage IV non-small-cell lung cancer after disease progression on platinum-based therapy. ESMO Open. 2020 01; 5(1).
Garon EB, Scagliotti GV, Gautschi O, Reck M, Thomas M, Iglesias Docampo L, Kalofonos H, Kim JH, Gans S, Brustugun OT, Orlov SV, Cuyun Carter G, Zimmermann AH, Oton AB, Alexandris E, Lee P, Wolff K, Stefaniak VJ, Socinski MA, Pérol M. PMID: 31958290; PMCID: PMC7003392.
View in:
PubMed Mentions:
6 Translation:
HumansCTClinical Trials
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KEYNOTE-042 rolls back programmed cell death ligand 1 threshold for non-small cell lung cancer pembrolizumab monotherapy without new insight into those deriving benefit. Transl Lung Cancer Res. 2019 Dec; 8(Suppl 4):S403-S406.
Cummings AL, Garon EB. PMID: 32038925; PMCID: PMC6987348.
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PubMed Mentions:
2
-
Ramucirumab plus erlotinib in patients with untreated, EGFR-mutated, advanced non-small-cell lung cancer (RELAY): a randomised, double-blind, placebo-controlled, phase 3 trial. Lancet Oncol. 2019 12; 20(12):1655-1669.
Nakagawa K, Garon EB, Seto T, Nishio M, Ponce Aix S, Paz-Ares L, Chiu CH, Park K, Novello S, Nadal E, Imamura F, Yoh K, Shih JY, Au KH, Moro-Sibilot D, Enatsu S, Zimmermann A, Frimodt-Moller B, Visseren-Grul C, Reck M, RELAY Study Investigators. PMID: 31591063.
View in:
PubMed Mentions:
267 Fields:
Translation:
HumansCTClinical Trials
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Pegilodecakin combined with pembrolizumab or nivolumab for patients with advanced solid tumours (IVY): a multicentre, multicohort, open-label, phase 1b trial. Lancet Oncol. 2019 11; 20(11):1544-1555.
Naing A, Wong DJ, Infante JR, Korn WM, Aljumaily R, Papadopoulos KP, Autio KA, Pant S, Bauer TM, Drakaki A, Daver NG, Hung A, Ratti N, McCauley S, Van Vlasselaer P, Verma R, Ferry D, Oft M, Diab A, Garon EB, Tannir NM. PMID: 31563517; PMCID: PMC8436252.
View in:
PubMed Mentions:
63 Fields:
Translation:
HumansCTClinical Trials
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Knowledge Gaps and Research Priorities in Immune Checkpoint Inhibitor-related Pneumonitis. An Official American Thoracic Society Research Statement. Am J Respir Crit Care Med. 2019 09 15; 200(6):e31-e43.
Sears CR, Peikert T, Possick JD, Naidoo J, Nishino M, Patel SP, Camus P, Gaga M, Garon EB, Gould MK, Limper AH, Montgrain PR, Travis WD, Rivera MP. PMID: 31518182; PMCID: PMC6775885.
View in:
PubMed Mentions:
58 Fields:
Translation:
Humans
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Five-Year Overall Survival for Patients With Advanced Non‒Small-Cell Lung Cancer Treated With Pembrolizumab: Results From the Phase I KEYNOTE-001 Study. J Clin Oncol. 2019 10 01; 37(28):2518-2527.
Garon EB, Hellmann MD, Rizvi NA, Carcereny E, Leighl NB, Ahn MJ, Eder JP, Balmanoukian AS, Aggarwal C, Horn L, Patnaik A, Gubens M, Ramalingam SS, Felip E, Goldman JW, Scalzo C, Jensen E, Kush DA, Hui R. PMID: 31154919; PMCID: PMC6768611.
View in:
PubMed Mentions:
525 Fields:
Translation:
HumansCTClinical Trials
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Luminespib plus pemetrexed in patients with non-squamous non-small cell lung cancer. Lung Cancer. 2019 09; 135:104-109.
Noor ZS, Goldman JW, Lawler WE, Telivala B, Braiteh F, DiCarlo BA, Kennedy K, Adams B, Wang X, Jones B, Slamon DJ, Garon EB. PMID: 31446981.
View in:
PubMed Mentions:
4 Fields:
Translation:
Humans
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Tumor Characteristics Associated with Benefit from Pembrolizumab in Advanced Non-Small Cell Lung Cancer. Clin Cancer Res. 2019 08 15; 25(16):5061-5068.
Hu-Lieskovan S, Lisberg A, Zaretsky JM, Grogan TR, Rizvi H, Wells DK, Carroll J, Cummings A, Madrigal J, Jones B, Gukasyan J, Shintaku IP, Slamon D, Dubinett S, Goldman JW, Elashoff D, Hellmann MD, Ribas A, Garon EB. PMID: 31113840; PMCID: PMC6901027.
View in:
PubMed Mentions:
40 Fields:
Translation:
Humans
-
Safety, Efficacy, and Patient-Reported Health-Related Quality of Life and Symptom Burden with Nivolumab in Patients with Advanced Non-Small Cell Lung Cancer, Including Patients Aged 70 Years or Older or with Poor Performance Status (CheckMate 153). J Thorac Oncol. 2019 09; 14(9):1628-1639.
Spigel DR, McCleod M, Jotte RM, Einhorn L, Horn L, Waterhouse DM, Creelan B, Babu S, Leighl NB, Chandler JC, Couture F, Keogh G, Goss G, Daniel DB, Garon EB, Schwartzberg LS, Sen R, Korytowsky B, Li A, Aanur N, Hussein MA. PMID: 31121324.
View in:
PubMed Mentions:
82 Fields:
Translation:
Humans
-
Lack of clearly defined role for anti-programmed death-(ligand) 1 therapy in epidermal growth factor receptor mutated non-small cell lung cancer. Transl Lung Cancer Res. 2019 Apr; 8(2):195-197.
Lisberg A, Garon EB. PMID: 31106131; PMCID: PMC6504648.
View in:
PubMed Mentions:
2
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Pembrolizumab in patients with advanced non-small-cell lung cancer (KEYNOTE-001): 3-year results from an open-label, phase 1 study. Lancet Respir Med. 2019 04; 7(4):347-357.
Leighl NB, Hellmann MD, Hui R, Carcereny E, Felip E, Ahn MJ, Eder JP, Balmanoukian AS, Aggarwal C, Horn L, Patnaik A, Gubens M, Ramalingam SS, Lubiniecki GM, Zhang J, Piperdi B, Garon EB. PMID: 30876831.
View in:
PubMed Mentions:
99 Fields:
Translation:
HumansCTClinical Trials
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Management of common adverse events related to first-line dacomitinib use in EGFR mutation-positive non-small-cell lung cancer: a pooled safety analysis. Future Oncol. 2019 May; 15(13):1481-1491.
Zhou Q, Wu YL, Corral J, Nakagawa K, Garon EB, Sbar EI, Wang T, Sandin R, Noonan K, Gernhardt D, Mok TS. PMID: 30839234.
View in:
PubMed Mentions:
4 Fields:
Translation:
Humans
-
Association of baseline symptom burden with efficacy outcomes: Exploratory analysis from the randomized phase III REVEL study in advanced non-small-cell lung cancer. Lung Cancer. 2019 05; 131:6-13.
Pérol M, Winfree KB, Cuyun Carter G, Lin Cui Z, Bowman L, Garon EB. PMID: 31027699.
View in:
PubMed Mentions:
6 Fields:
Translation:
HumansCTClinical Trials
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Nivolumab in Previously Treated SCLC: Encouraging, but Still Awaiting the Complete Story. J Thorac Oncol. 2019 02; 14(2):160-162.
Goldman JW, Garon EB. PMID: 30683290.
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PubMed Mentions: Fields:
Translation:
Humans
-
Health-Related Quality of Life in KEYNOTE-010: a Phase II/III Study of Pembrolizumab Versus Docetaxel in Patients With Previously Treated Advanced, Programmed Death Ligand 1-Expressing NSCLC. J Thorac Oncol. 2019 05; 14(5):793-801.
Barlesi F, Garon EB, Kim DW, Felip E, Han JY, Kim JH, Ahn MJ, Fidler MJ, Gubens MA, de Castro G, Surmont V, Li Q, Deitz AC, Lubiniecki GM, Herbst RS. PMID: 30711649.
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PubMed Mentions:
33 Fields:
Translation:
HumansCTClinical Trials
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Does Platinum-Based Chemotherapy Still Have a Role in First-Line Treatment of Advanced Non-Small-Cell Lung Cancer? J Clin Oncol. 2019 03 01; 37(7):529-536.
Lisberg A, Garon EB. PMID: 30676857.
View in:
PubMed Mentions:
4 Fields:
Translation:
Humans
-
Low Concordance of Patient-Reported Outcomes With Clinical and Clinical Trial Documentation. JCO Clin Cancer Inform. 2018 12; 2:1-12.
Fares CM, Williamson TJ, Theisen MK, Cummings A, Bornazyan K, Carroll J, Spiegel ML, Stanton AL, Garon EB. PMID: 30652613; PMCID: PMC6724714.
View in:
PubMed Mentions:
10 Fields:
Translation:
Humans
-
Are lung adenocarcinoma mutations shaping the immune microenvironment? Transl Cancer Res. 2018 Aug; 7(Suppl 7):S740-S742.
Rochigneux P, Garon EB. PMID: 30906701; PMCID: PMC6430579.
View in:
PubMed Mentions:
2
-
Torsades de pointes with pseudo-T wave alternans during rociletinib therapy: A novel manifestation of a rare side effect. HeartRhythm Case Rep. 2018 Oct; 4(10):490-493.
Teng AE, Share M, Hsu JJ, Rettinger SR, Garon E, Goldman J, Yang EH, Tung R. PMID: 30364475; PMCID: PMC6197170.
View in:
PubMed Mentions:
1
-
The Society for Immunotherapy of Cancer consensus statement on immunotherapy for the treatment of non-small cell lung cancer (NSCLC). J Immunother Cancer. 2018 07 17; 6(1):75.
Brahmer JR, Govindan R, Anders RA, Antonia SJ, Sagorsky S, Davies MJ, Dubinett SM, Ferris A, Gandhi L, Garon EB, Hellmann MD, Hirsch FR, Malik S, Neal JW, Papadimitrakopoulou VA, Rimm DL, Schwartz LH, Sepesi B, Yeap BY, Rizvi NA, Herbst RS. PMID: 30012210; PMCID: PMC6048854.
View in:
PubMed Mentions:
136 Fields:
Translation:
Humans
-
A Longitudinal Investigation of Internalized Stigma, Constrained Disclosure, and Quality of Life Across 12 Weeks in Lung Cancer Patients on Active Oncologic Treatment. J Thorac Oncol. 2018 09; 13(9):1284-1293.
Williamson TJ, Choi AK, Kim JC, Garon EB, Shapiro JR, Irwin MR, Goldman JW, Bornyazan K, Carroll JM, Stanton AL. PMID: 29981926; PMCID: PMC6291203.
View in:
PubMed Mentions:
19 Fields:
Translation:
Humans
-
The Italian Nivolumab Expanded Access Program Confirms the Limitations of Single-Agent PD-1 Inhibition in EGFR-Mutant and Never-Smoking Patients with NSCLC. J Thorac Oncol. 2018 08; 13(8):1058-1059.
Lisberg A, Garon EB. PMID: 30056858.
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PubMed Mentions:
4 Fields:
Translation:
Humans
-
Randomized phase II study of fulvestrant and erlotinib compared with erlotinib alone in patients with advanced or metastatic non-small cell lung cancer. Lung Cancer. 2018 09; 123:91-98.
Garon EB, Siegfried JM, Stabile LP, Young PA, Marquez-Garban DC, Park DJ, Patel R, Hu EH, Sadeghi S, Parikh RJ, Reckamp KL, Adams B, Elashoff RM, Elashoff D, Grogan T, Wang HJ, Dacic S, Brennan M, Valdes Y, Davenport S, Dubinett SM, Press MF, Slamon DJ, Pietras RJ. PMID: 30089602; PMCID: PMC6118115.
View in:
PubMed Mentions:
25 Fields:
Translation:
HumansCTClinical Trials
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Pembrolizumab Exposure-Response Assessments Challenged by Association of Cancer Cachexia and Catabolic Clearance. Clin Cancer Res. 2018 12 01; 24(23):5841-5849.
Turner DC, Kondic AG, Anderson KM, Robinson AG, Garon EB, Riess JW, Jain L, Mayawala K, Kang J, Ebbinghaus SW, Sinha V, de Alwis DP, Stone JA. PMID: 29891725.
View in:
PubMed Mentions:
102 Fields:
Translation:
Humans
-
A Phase II Study of Pembrolizumab in EGFR-Mutant, PD-L1+, Tyrosine Kinase Inhibitor Naïve Patients With Advanced NSCLC. J Thorac Oncol. 2018 08; 13(8):1138-1145.
Lisberg A, Cummings A, Goldman JW, Bornazyan K, Reese N, Wang T, Coluzzi P, Ledezma B, Mendenhall M, Hunt J, Wolf B, Jones B, Madrigal J, Horton J, Spiegel M, Carroll J, Gukasyan J, Williams T, Sauer L, Wells C, Hardy A, Linares P, Lim C, Ma L, Adame C, Garon EB. PMID: 29874546; PMCID: PMC6063769.
View in:
PubMed Mentions:
266 Fields:
Translation:
HumansCTClinical Trials
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Exposure-response relationship for ramucirumab from the randomized, double-blind, phase 3 REVEL trial (docetaxel versus docetaxel plus ramucirumab) in second-line treatment of metastatic non-small cell lung cancer. Cancer Chemother Pharmacol. 2018 07; 82(1):77-86.
Smit EF, Garon EB, Reck M, Cappuzzo F, Bidoli P, Cohen RB, Gao L, O'Brien LM, Lee P, Zimmermann A, Ferry DR, Melemed AS, Pérol M. PMID: 29721850.
View in:
PubMed Mentions:
6 Fields:
Translation:
HumansCTClinical Trials
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Pembrolizumab plus Chemotherapy in Metastatic Non-Small-Cell Lung Cancer. N Engl J Med. 2018 May 31; 378(22):2078-2092.
Gandhi L, Rodríguez-Abreu D, Gadgeel S, Esteban E, Felip E, De Angelis F, Domine M, Clingan P, Hochmair MJ, Powell SF, Cheng SY, Bischoff HG, Peled N, Grossi F, Jennens RR, Reck M, Hui R, Garon EB, Boyer M, Rubio-Viqueira B, Novello S, Kurata T, Gray JE, Vida J, Wei Z, Yang J, Raftopoulos H, Pietanza MC, Garassino MC, KEYNOTE-189 Investigators. PMID: 29658856.
View in:
PubMed Mentions:
2864 Fields:
Translation:
HumansCTClinical Trials
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Antiangiogenic therapy for patients with aggressive or refractory advanced non-small cell lung cancer in the second-line setting. Lung Cancer. 2018 06; 120:62-69.
Reck M, Garassino MC, Imbimbo M, Shepherd FA, Socinski MA, Shih JY, Tsao A, Lee P, Winfree KB, Sashegyi A, Cheng R, Varea R, Levy B, Garon E. PMID: 29748017.
View in:
PubMed Mentions:
20 Fields:
Translation:
HumansAnimals
-
A Prospective Phase 2 Study Evaluating Safety and Efficacy of Combining Stereotactic Body Radiation Therapy With Heat-based Ablation for Centrally Located Lung Tumors. Int J Radiat Oncol Biol Phys. 2018 07 01; 101(3):564-573.
Sandler KA, Abtin F, Suh R, Cook RR, Felix C, Lee JM, Garon EB, Wu J, Luterstein EM, Agazaryan N, Tenn SE, Lee C, Steinberg ML, Lee P. PMID: 29893274.
View in:
PubMed Mentions:
7 Fields:
Translation:
HumansCTClinical Trials
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Phase 1/2 Study of the Safety and Tolerability of Nivolumab Plus Crizotinib for the First-Line Treatment of Anaplastic Lymphoma Kinase Translocation - Positive Advanced Non-Small Cell Lung Cancer (CheckMate 370). J Thorac Oncol. 2018 05; 13(5):682-688.
Spigel DR, Reynolds C, Waterhouse D, Garon EB, Chandler J, Babu S, Thurmes P, Spira A, Jotte R, Zhu J, Lin WH, Blumenschein G. PMID: 29518553.
View in:
PubMed Mentions:
117 Fields:
Translation:
HumansCTClinical Trials
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Evaluation of PD-L1 expression on vortex-isolated circulating tumor cells in metastatic lung cancer. Sci Rep. 2018 02 07; 8(1):2592.
Dhar M, Wong J, Che J, Matsumoto M, Grogan T, Elashoff D, Garon EB, Goldman JW, Sollier Christen E, Di Carlo D, Kulkarni RP. PMID: 29416054; PMCID: PMC5803213.
View in:
PubMed Mentions:
54 Fields:
Translation:
HumansCells
-
High-profile studies frequently and repetitively present data on the same patients, particularly in immunotherapy studies. J Thorac Dis. 2018 Feb; 10(Suppl 3):S397-S403.
Ellis-Caleo T, Lisberg A, Tucker DA, Garon EB. PMID: 29593885; PMCID: PMC5861271.
View in:
PubMed Mentions:
1
-
Treatment-Related Adverse Events Predict Improved Clinical Outcome in NSCLC Patients on KEYNOTE-001 at a Single Center. Cancer Immunol Res. 2018 03; 6(3):288-294.
Lisberg A, Tucker DA, Goldman JW, Wolf B, Carroll J, Hardy A, Morris K, Linares P, Adame C, Spiegel ML, Wells C, McKenzie J, Ledezma B, Mendenhall M, Abarca P, Bornazyan K, Hunt J, Moghadam N, Chong N, Nameth D, Marx C, Madrigal J, Vangala S, Shaverdian N, Elashoff D, Garon EB. PMID: 29382669; PMCID: PMC6066474.
View in:
PubMed Mentions:
51 Fields:
Translation:
HumansCTClinical Trials
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Efficacy and Safety of Ramucirumab With Docetaxel Versus Placebo With Docetaxel as Second-Line Treatment of Advanced Non-Small-Cell Lung Cancer: A Subgroup Analysis According to Patient Age in the REVEL Trial. Clin Lung Cancer. 2018 05; 19(3):270-279.e3.
Ramalingam SS, Pérol M, Reck M, Kowalyszyn RD, Gautschi O, Kimmich M, Cho EK, Czyzewicz G, Grigorescu A, Karaseva N, Dakhil S, Lee P, Zimmerman A, Sashegyi A, Alexandris E, Carter GC, Winfree KB, Garon EB. PMID: 29373274.
View in:
PubMed Mentions:
5 Fields:
Translation:
HumansCTClinical Trials
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Phase 2 Study of the HSP-90 Inhibitor AUY922 in Previously Treated and Molecularly Defined Patients with Advanced Non-Small Cell Lung Cancer. J Thorac Oncol. 2018 04; 13(4):576-584.
Felip E, Barlesi F, Besse B, Chu Q, Gandhi L, Kim SW, Carcereny E, Sequist LV, Brunsvig P, Chouaid C, Smit EF, Groen HJM, Kim DW, Park K, Avsar E, Szpakowski S, Akimov M, Garon EB. PMID: 29247830.
View in:
PubMed Mentions:
28 Fields:
Translation:
HumansCTClinical Trials
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Feasibility and Safety of Intrathoracic Biopsy and Repeat Biopsy for Evaluation of Programmed Cell Death Ligand-1 Expression for Immunotherapy in Non-Small Cell Lung Cancer. Radiology. 2018 04; 287(1):326-332.
Tsai EB, Pomykala K, Ruchalski K, Genshaft S, Abtin F, Gutierrez A, Kim HJ, Li A, Adame C, Jalalian A, Wolf B, Garon EB, Goldman JW, Suh R. PMID: 29232184; PMCID: PMC6276060.
View in:
PubMed Mentions:
12 Fields:
Translation:
Humans
-
Patient HLA class I genotype influences cancer response to checkpoint blockade immunotherapy. Science. 2018 02 02; 359(6375):582-587.
Chowell D, Morris LGT, Grigg CM, Weber JK, Samstein RM, Makarov V, Kuo F, Kendall SM, Requena D, Riaz N, Greenbaum B, Carroll J, Garon E, Hyman DM, Zehir A, Solit D, Berger M, Zhou R, Rizvi NA, Chan TA. PMID: 29217585; PMCID: PMC6057471.
View in:
PubMed Mentions:
541 Fields:
Translation:
HumansCells
-
The Impact of Smoking and TP53 Mutations in Lung Adenocarcinoma Patients with Targetable Mutations-The Lung Cancer Mutation Consortium (LCMC2). Clin Cancer Res. 2018 03 01; 24(5):1038-1047.
Aisner DL, Sholl LM, Berry LD, Rossi MR, Chen H, Fujimoto J, Moreira AL, Ramalingam SS, Villaruz LC, Otterson GA, Haura E, Politi K, Glisson B, Cetnar J, Garon EB, Schiller J, Waqar SN, Sequist LV, Brahmer J, Shyr Y, Kugler K, Wistuba II, Johnson BE, Minna JD, Kris MG, Bunn PA, Kwiatkowski DJ, LCMC2 investigators. PMID: 29217530; PMCID: PMC7008001.
View in:
PubMed Mentions:
86 Fields:
Translation:
Humans
-
Epidermal growth factor tyrosine kinase inhibitor therapy inferior to second-line chemotherapy in EGFR wild-type non-small cell lung cancer patients: results of French nationwide observational study. Transl Lung Cancer Res. 2017 Dec; 6(Suppl 1):S39-S40.
Lisberg A, Garon EB. PMID: 29299407; PMCID: PMC5750165.
View in:
PubMed Mentions:
5
-
Randomized, Double-Blind Phase Ib/III Study of Erlotinib With Ramucirumab or Placebo in Previously Untreated EGFR-Mutant Metastatic Non-Small-Cell Lung Cancer (RELAY): Phase Ib Results. Clin Lung Cancer. 2018 05; 19(3):213-220.e4.
Reck M, Garon EB, Paz-Ares L, Ponce S, Jaime JC, Juan O, Nadal E, Kiura K, Widau RC, He S, Dalal R, Lee P, Nakagawa K. PMID: 29317191.
View in:
PubMed Mentions:
6 Fields:
Translation:
HumansCTClinical Trials
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Non-small cell lung cancer clinical trials requiring biopsies with biomarker-specific results for enrollment provide unique challenges. Cancer. 2017 Dec 15; 123(24):4800-4807.
Spiegel ML, Goldman JW, Wolf BR, Nameth DJ, Grogan TR, Lisberg AE, Wong DJL, Ledezma BA, Mendenhall MA, Genshaft SJ, Gutierrez AJ, Abtin F, Wallace WD, Adame CR, McKenzie JR, Abarca PA, Li AJ, Strunck JL, Famenini S, Carroll JM, Tucker DA, Sauer LM, Moghadam NM, Elashoff DA, Abaya CD, Brennan MB, Garon EB. PMID: 29125624; PMCID: PMC6263029.
View in:
PubMed Mentions:
10 Fields:
Translation:
Humans
-
Evaluating Casama: Contextualized semantic maps for summarization of lung cancer studies. Comput Biol Med. 2018 01 01; 92:55-63.
Garcia-Gathright JI, Matiasz NJ, Adame C, Sarma KV, Sauer L, Smedley NF, Spiegel ML, Strunck J, Garon EB, Taira RK, Aberle DR, Bui AAT. PMID: 29149658; PMCID: PMC5762403.
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PubMed Mentions: Fields:
Translation:
Humans
-
The ascent of immune checkpoint inhibitors: is the understudy ready for a leading role? Cancer Biol Med. 2017 Nov; 14(4):341-347.
Cummings AL, Garon EB. PMID: 29372100; PMCID: PMC5785166.
View in:
PubMed Mentions:
2 Fields:
-
Cancer Immunotherapy Trials Not Immune from Imprecise Selection of Patients. N Engl J Med. 2017 06 22; 376(25):2483-2485.
Garon EB. PMID: 28636845.
View in:
PubMed Mentions:
22 Fields:
Translation:
Humans
-
Clinical Implications of the T790M Mutation in Disease Characteristics and Treatment Response in Patients With Epidermal Growth Factor Receptor (EGFR)-Mutated Non-Small-Cell Lung Cancer (NSCLC). Clin Lung Cancer. 2018 01; 19(1):e19-e28.
Gaut D, Sim MS, Yue Y, Wolf BR, Abarca PA, Carroll JM, Goldman JW, Garon EB. PMID: 28712979; PMCID: PMC5761337.
View in:
PubMed Mentions:
10 Fields:
Translation:
Humans
-
Treatment outcomes by histology in REVEL: A randomized phase III trial of Ramucirumab plus docetaxel for advanced non-small cell lung cancer. Lung Cancer. 2017 10; 112:126-133.
Paz-Ares LG, Pérol M, Ciuleanu TE, Kowalyszyn RD, Reck M, Lewanski CR, Syrigos K, Arrieta O, Prabhash K, Park K, Pikiel J, Göksel T, Lee P, Zimmermann A, Carter GC, Alexandris E, Garon EB. PMID: 29191585.
View in:
PubMed Mentions:
6 Fields:
Translation:
HumansCTClinical Trials
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Previous radiotherapy and the clinical activity and toxicity of pembrolizumab in the treatment of non-small-cell lung cancer: a secondary analysis of the KEYNOTE-001 phase 1 trial. Lancet Oncol. 2017 07; 18(7):895-903.
Shaverdian N, Lisberg AE, Bornazyan K, Veruttipong D, Goldman JW, Formenti SC, Garon EB, Lee P. PMID: 28551359; PMCID: PMC5538772.
View in:
PubMed Mentions:
518 Fields:
Translation:
HumansCTClinical Trials
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Phase I Trial of Intratumoral Injection of CCL21 Gene-Modified Dendritic Cells in Lung Cancer Elicits Tumor-Specific Immune Responses and CD8+ T-cell Infiltration. Clin Cancer Res. 2017 Aug 15; 23(16):4556-4568.
Lee JM, Lee MH, Garon E, Goldman JW, Salehi-Rad R, Baratelli FE, Schaue D, Wang G, Rosen F, Yanagawa J, Walser TC, Lin Y, Park SJ, Adams S, Marincola FM, Tumeh PC, Abtin F, Suh R, Reckamp KL, Lee G, Wallace WD, Lee S, Zeng G, Elashoff DA, Sharma S, Dubinett SM. PMID: 28468947; PMCID: PMC5599263.
View in:
PubMed Mentions:
113 Fields:
Translation:
HumansCellsCTClinical Trials
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Liver Metastasis and Treatment Outcome with Anti-PD-1 Monoclonal Antibody in Patients with Melanoma and NSCLC. Cancer Immunol Res. 2017 05; 5(5):417-424.
Tumeh PC, Hellmann MD, Hamid O, Tsai KK, Loo KL, Gubens MA, Rosenblum M, Harview CL, Taube JM, Handley N, Khurana N, Nosrati A, Krummel MF, Tucker A, Sosa EV, Sanchez PJ, Banayan N, Osorio JC, Nguyen-Kim DL, Chang J, Shintaku IP, Boasberg PD, Taylor EJ, Munster PN, Algazi AP, Chmielowski B, Dummer R, Grogan TR, Elashoff D, Hwang J, Goldinger SM, Garon EB, Pierce RH, Daud A. PMID: 28411193; PMCID: PMC5749922.
View in:
PubMed Mentions:
308 Fields:
Translation:
HumansCellsCTClinical Trials
-
Biophysical isolation and identification of circulating tumor cells. Lab Chip. 2017 04 11; 17(8):1452-1461.
Che J, Yu V, Garon EB, Goldman JW, Di Carlo D. PMID: 28352869; PMCID: PMC5507599.
View in:
PubMed Mentions:
34 Fields:
Translation:
HumansCells
-
Impact of a planned dose interruption of dacomitinib in the treatment of advanced non-small-cell lung cancer (ARCHER 1042). Lung Cancer. 2017 04; 106:76-82.
Kim DW, Garon EB, Jatoi A, Keefe DM, Lacouture ME, Sonis S, Gernhardt D, Wang T, Giri N, Doherty JP, Nadanaciva S, O'Connell J, Sbar E, Cho BC. PMID: 28285698; PMCID: PMC5552055.
View in:
PubMed Mentions:
3 Fields:
Translation:
HumansCTClinical Trials
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Targeted Inhibition of EGFR and Glutaminase Induces Metabolic Crisis in EGFR Mutant Lung Cancer. Cell Rep. 2017 01 17; 18(3):601-610.
Momcilovic M, Bailey ST, Lee JT, Fishbein MC, Magyar C, Braas D, Graeber T, Jackson NJ, Czernin J, Emberley E, Gross M, Janes J, Mackinnon A, Pan A, Rodriguez M, Works M, Zhang W, Parlati F, Demo S, Garon E, Krysan K, Walser TC, Dubinett SM, Sadeghi S, Christofk HR, Shackelford DB. PMID: 28099841; PMCID: PMC5260616.
View in:
PubMed Mentions:
80 Fields:
Translation:
HumansAnimalsCells
-
A randomized Phase II trial of the tumor vascular disrupting agent CA4P (fosbretabulin tromethamine) with carboplatin, paclitaxel, and bevacizumab in advanced nonsquamous non-small-cell lung cancer. Onco Targets Ther. 2016; 9:7275-7283.
Garon EB, Neidhart JD, Gabrail NY, de Oliveira MR, Balkissoon J, Kabbinavar F. PMID: 27942221; PMCID: PMC5138047.
View in:
PubMed Mentions:
26
-
Label-free enumeration, collection and downstream cytological and cytogenetic analysis of circulating tumor cells. Sci Rep. 2016 10 14; 6:35474.
Dhar M, Pao E, Renier C, Go DE, Che J, Montoya R, Conrad R, Matsumoto M, Heirich K, Triboulet M, Rao J, Jeffrey SS, Garon EB, Goldman J, Rao NP, Kulkarni R, Sollier-Christen E, Di Carlo D. PMID: 27739521; PMCID: PMC5064381.
View in:
PubMed Mentions:
29 Fields:
Translation:
HumansCells
-
Immunotherapy of non-small cell lung cancer: report from an international experts panel meeting of the Italian association of thoracic oncology. Expert Opin Biol Ther. 2016 12; 16(12):1479-1489.
Gridelli C, Ascierto PA, Barberis MC, Felip E, Garon EB, O'brien M, Senan S, Casaluce F, Sgambato A, Papadimitrakopoulou V, De Marinis F. PMID: 27650132.
View in:
PubMed Mentions:
7 Fields:
Translation:
Humans
-
Treatment Rationale and Study Design for the RELAY Study: A Multicenter, Randomized, Double-Blind Study of Erlotinib With Ramucirumab or Placebo in Patients With Epidermal Growth Factor Receptor Mutation-Positive Metastatic Non-Small-Cell Lung Cancer. Clin Lung Cancer. 2017 01; 18(1):96-99.
Garon EB, Reck M, Paz-Ares L, Ponce S, Jaime JC, Juan O, Nadal E, Lee P, Dalal R, Liu J, He S, Treat J, Nakagawa K. PMID: 27894601.
View in:
PubMed Mentions:
5 Fields:
Translation:
HumansCTClinical Trials
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The Value of PD-L1 Testing in Non-Small-Cell Lung Cancer. JAMA Oncol. 2016 May 01; 2(5):571-572.
Lisberg A, Garon EB. PMID: 26986923.
View in:
PubMed Mentions:
8 Fields:
-
Toward patient-tailored summarization of lung cancer literature. IEEE EMBS Int Conf Biomed Health Inform. 2016 Feb; 2016:449-452.
Garcia-Gathright JI, Matiasz NJ, Garon EB, Aberle DR, Taira RK, Bui AAT. PMID: 28721401; PMCID: PMC5511748.
View in:
PubMed Mentions:
1
-
Classification of large circulating tumor cells isolated with ultra-high throughput microfluidic Vortex technology. Oncotarget. 2016 Mar 15; 7(11):12748-60.
Che J, Yu V, Dhar M, Renier C, Matsumoto M, Heirich K, Garon EB, Goldman J, Rao J, Sledge GW, Pegram MD, Sheth S, Jeffrey SS, Kulkarni RP, Sollier E, Di Carlo D. PMID: 26863573; PMCID: PMC4914319.
View in:
PubMed Mentions:
77 Fields:
Translation:
HumansCells
-
The race for combined checkpoint inhibition in NSCLC. Lancet Oncol. 2016 Mar; 17(3):259-260.
Garon EB. PMID: 26858123.
View in:
PubMed Mentions:
4 Fields:
Translation:
Humans
-
Quality of life results from the phase 3 REVEL randomized clinical trial of ramucirumab-plus-docetaxel versus placebo-plus-docetaxel in advanced/metastatic non-small cell lung cancer patients with progression after platinum-based chemotherapy. Lung Cancer. 2016 Mar; 93:95-103.
Pérol M, Ciuleanu TE, Arrieta O, Prabhash K, Syrigos KN, Goksel T, Park K, Kowalyszyn RD, Pikiel J, Lewanski CR, Thomas M, Dakhil S, Kim JH, Karaseva N, Yurasov S, Zimmermann A, Lee P, Carter GC, Reck M, Cappuzzo F, Garon EB. PMID: 26898621.
View in:
PubMed Mentions:
16 Fields:
Translation:
HumansCTClinical Trials
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Role of race in oncogenic driver prevalence and outcomes in lung adenocarcinoma: Results from the Lung Cancer Mutation Consortium. Cancer. 2016 Mar 01; 122(5):766-72.
Steuer CE, Behera M, Berry L, Kim S, Rossi M, Sica G, Owonikoko TK, Johnson BE, Kris MG, Bunn PA, Khuri FR, Garon EB, Ramalingam SS. PMID: 26695526; PMCID: PMC5038591.
View in:
PubMed Mentions:
52 Fields:
Translation:
Humans
-
Pembrolizumab versus docetaxel for previously treated, PD-L1-positive, advanced non-small-cell lung cancer (KEYNOTE-010): a randomised controlled trial. Lancet. 2016 Apr 09; 387(10027):1540-1550.
Herbst RS, Baas P, Kim DW, Felip E, Pérez-Gracia JL, Han JY, Molina J, Kim JH, Arvis CD, Ahn MJ, Majem M, Fidler MJ, de Castro G, Garrido M, Lubiniecki GM, Shentu Y, Im E, Dolled-Filhart M, Garon EB. PMID: 26712084.
View in:
PubMed Mentions:
3076 Fields:
Translation:
Humans
-
High efficiency vortex trapping of circulating tumor cells. Biomicrofluidics. 2015 Nov; 9(6):064116.
Dhar M, Wong J, Karimi A, Che J, Renier C, Matsumoto M, Triboulet M, Garon EB, Goldman JW, Rettig MB, Jeffrey SS, Kulkarni RP, Sollier E, Di Carlo D. PMID: 26697126; PMCID: PMC4684572.
View in:
PubMed Mentions:
20
-
Current Perspectives in Immunotherapy for Non-Small Cell Lung Cancer. Semin Oncol. 2015 Oct; 42 Suppl 2:S11-8.
Garon EB. PMID: 26477470.
View in:
PubMed Mentions:
31 Fields:
Translation:
Humans
-
Selecting patients for immune checkpoint inhibition in lung cancer. Clin Adv Hematol Oncol. 2015 Aug; 13(8):490-2.
Garon EB. PMID: 26351808.
View in:
PubMed Mentions:
1 Fields:
Translation:
Humans
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Patient Portal Preferences: Perspectives on Imaging Information. J Assoc Inf Sci Technol. 2015 Aug 01; 66(8):1606-1615.
McNamara M, Arnold C, Sarma K, Aberle D, Garon E, Bui AA. PMID: 26191535; PMCID: PMC4504683.
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PubMed Mentions:
10
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Rociletinib in EGFR-mutated non-small-cell lung cancer. N Engl J Med. 2015 Apr 30; 372(18):1700-9.
Sequist LV, Soria JC, Goldman JW, Wakelee HA, Gadgeel SM, Varga A, Papadimitrakopoulou V, Solomon BJ, Oxnard GR, Dziadziuszko R, Aisner DL, Doebele RC, Galasso C, Garon EB, Heist RS, Logan J, Neal JW, Mendenhall MA, Nichols S, Piotrowska Z, Wozniak AJ, Raponi M, Karlovich CA, Jaw-Tsai S, Isaacson J, Despain D, Matheny SL, Rolfe L, Allen AR, Camidge DR. PMID: 25923550.
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PubMed Mentions:
269 Fields:
Translation:
HumansCTClinical Trials
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Pembrolizumab for the treatment of non-small-cell lung cancer. N Engl J Med. 2015 May 21; 372(21):2018-28.
Garon EB, Rizvi NA, Hui R, Leighl N, Balmanoukian AS, Eder JP, Patnaik A, Aggarwal C, Gubens M, Horn L, Carcereny E, Ahn MJ, Felip E, Lee JS, Hellmann MD, Hamid O, Goldman JW, Soria JC, Dolled-Filhart M, Rutledge RZ, Zhang J, Lunceford JK, Rangwala R, Lubiniecki GM, Roach C, Emancipator K, Gandhi L, KEYNOTE-001 Investigators. PMID: 25891174.
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PubMed Mentions:
3057 Fields:
Translation:
HumansCTClinical Trials
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Cancer immunology. Mutational landscape determines sensitivity to PD-1 blockade in non-small cell lung cancer. Science. 2015 Apr 03; 348(6230):124-8.
Rizvi NA, Hellmann MD, Snyder A, Kvistborg P, Makarov V, Havel JJ, Lee W, Yuan J, Wong P, Ho TS, Miller ML, Rekhtman N, Moreira AL, Ibrahim F, Bruggeman C, Gasmi B, Zappasodi R, Maeda Y, Sander C, Garon EB, Merghoub T, Wolchok JD, Schumacher TN, Chan TA. PMID: 25765070; PMCID: PMC4993154.
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PubMed Mentions:
4191 Fields:
Translation:
HumansCells
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Quality of life analyses from the randomized, open-label, phase III PointBreak study of pemetrexed-carboplatin-bevacizumab followed by maintenance pemetrexed-bevacizumab versus paclitaxel-carboplatin-bevacizumab followed by maintenance bevacizumab in patients with stage IIIB or IV nonsquamous non-small-cell lung cancer. J Thorac Oncol. 2015 Feb; 10(2):353-9.
Spigel DR, Patel JD, Reynolds CH, Garon EB, Hermann RC, Govindan R, Olsen MR, Winfree KB, Chen J, Liu J, Guba SC, Socinski MA, Bonomi P. PMID: 25611228.
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PubMed Mentions:
13 Fields:
Translation:
HumansCTClinical Trials
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Representing and extracting lung cancer study metadata: study objective and study design. Comput Biol Med. 2015 Mar; 58:63-72.
Garcia-Gathright JI, Oh A, Abarca PA, Han M, Sago W, Spiegel ML, Wolf B, Garon EB, Bui AA, Aberle DR. PMID: 25618216; PMCID: PMC4331232.
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PubMed Mentions:
2 Fields:
Translation:
Humans
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Alectinib induces a durable (>15 months) complete response in an ALK-positive non-small cell lung cancer patient who progressed on crizotinib with diffuse leptomeningeal carcinomatosis. Oncologist. 2015 Feb; 20(2):224-6.
Ou SH, Sommers KR, Azada MC, Garon EB. PMID: 25568147; PMCID: PMC4319629.
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PubMed Mentions:
22 Fields:
Translation:
Humans
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Estrogen Receptor-β and the Insulin-Like Growth Factor Axis as Potential Therapeutic Targets for Triple-Negative Breast Cancer. Crit Rev Oncog. 2015; 20(5-6):373-90.
Hamilton N, Marquez-Garban D, Mah VH, Elshimali Y, Elashoff D, Garon EB, Vadgama J, Pietras R. PMID: 27279236; PMCID: PMC5495464.
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PubMed Mentions:
5 Fields:
Translation:
Humans
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Molecularly targeted therapies in non-small-cell lung cancer annual update 2014. J Thorac Oncol. 2015 Jan; 10(1 Suppl 1):S1-63.
Morgensztern D, Campo MJ, Dahlberg SE, Doebele RC, Garon E, Gerber DE, Goldberg SB, Hammerman PS, Heist RS, Hensing T, Horn L, Ramalingam SS, Rudin CM, Salgia R, Sequist LV, Shaw AT, Simon GR, Somaiah N, Spigel DR, Wrangle J, Johnson D, Herbst RS, Bunn P, Govindan R. PMID: 25535693; PMCID: PMC4346098.
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PubMed Mentions:
60 Fields:
Translation:
Humans
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Clinical Trials in Non-Small Cell Lung Cancer with Biomarker-Driven Treatment Allocation: Ready or Not, Here We Come. Crit Rev Oncog. 2015; 20(5-6):339-47.
Garon EB, Abarca PA, Strunck JL, Nameth D, Neumann C, Wolf B, Kim KY, Marx C, Elashoff RM. PMID: 27279233; PMCID: PMC5273860.
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PubMed Mentions:
1 Fields:
Translation:
Humans
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Exploratory Subset Analysis of African Americans From the PointBreak Study: Pemetrexed-Carboplatin-Bevacizumab Followed by Maintenance Pemetrexed-Bevacizumab Versus Paclitaxel-Carboplatin-Bevacizumab Followed by Maintenance Bevacizumab in Patients With Stage IIIB/IV Nonsquamous Non-Small-Cell Lung Cancer. Clin Lung Cancer. 2015 May; 16(3):200-8.
Reynolds CH, Patel JD, Garon EB, Olsen MR, Bonomi P, Govindan R, Pennella EJ, Liu J, Guba SC, Li S, Spigel DR, Hermann RC, Socinski MA, Obasaju CK. PMID: 25516338.
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PubMed Mentions:
4 Fields:
Translation:
HumansCTClinical Trials
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Ramucirumab plus docetaxel versus placebo plus docetaxel for second-line treatment of stage IV non-small-cell lung cancer after disease progression on platinum-based therapy (REVEL): a multicentre, double-blind, randomised phase 3 trial. Lancet. 2014 Aug 23; 384(9944):665-73.
Garon EB, Ciuleanu TE, Arrieta O, Prabhash K, Syrigos KN, Goksel T, Park K, Gorbunova V, Kowalyszyn RD, Pikiel J, Czyzewicz G, Orlov SV, Lewanski CR, Thomas M, Bidoli P, Dakhil S, Gans S, Kim JH, Grigorescu A, Karaseva N, Reck M, Cappuzzo F, Alexandris E, Sashegyi A, Yurasov S, Pérol M. PMID: 24933332.
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PubMed Mentions:
547 Fields:
Translation:
HumansCTClinical Trials
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Using multiplexed assays of oncogenic drivers in lung cancers to select targeted drugs. JAMA. 2014 May 21; 311(19):1998-2006.
Kris MG, Johnson BE, Berry LD, Kwiatkowski DJ, Iafrate AJ, Wistuba II, Varella-Garcia M, Franklin WA, Aronson SL, Su PF, Shyr Y, Camidge DR, Sequist LV, Glisson BS, Khuri FR, Garon EB, Pao W, Rudin C, Schiller J, Haura EB, Socinski M, Shirai K, Chen H, Giaccone G, Ladanyi M, Kugler K, Minna JD, Bunn PA. PMID: 24846037; PMCID: PMC4163053.
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PubMed Mentions:
831 Fields:
Translation:
HumansCTClinical Trials
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Incidental mediastinal dose does not explain low mediastinal node recurrence rates in patients with early-stage NSCLC treated with stereotactic body radiotherapy. Clin Lung Cancer. 2014 Jul; 15(4):287-93.
Rwigema JC, Chen AM, Wang PC, Lee JM, Garon E, Lee P. PMID: 24594401.
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PubMed Mentions:
8 Fields:
Translation:
Humans
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PGE2-driven expression of c-Myc and oncomiR-17-92 contributes to apoptosis resistance in NSCLC. Mol Cancer Res. 2014 May; 12(5):765-74.
Krysan K, Kusko R, Grogan T, O'Hearn J, Reckamp KL, Walser TC, Garon EB, Lenburg ME, Sharma S, Spira AE, Elashoff D, Dubinett SM. PMID: 24469837; PMCID: PMC4020971.
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PubMed Mentions:
14 Fields:
Translation:
HumansCells
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Dichloroacetate should be considered with platinum-based chemotherapy in hypoxic tumors rather than as a single agent in advanced non-small cell lung cancer. J Cancer Res Clin Oncol. 2014 Mar; 140(3):443-52.
Garon EB, Christofk HR, Hosmer W, Britten CD, Bahng A, Crabtree MJ, Hong CS, Kamranpour N, Pitts S, Kabbinavar F, Patel C, von Euw E, Black A, Michelakis ED, Dubinett SM, Slamon DJ. PMID: 24442098; PMCID: PMC3939783.
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PubMed Mentions:
64 Fields:
Translation:
HumansCellsCTClinical Trials
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PointBreak: a randomized phase III study of pemetrexed plus carboplatin and bevacizumab followed by maintenance pemetrexed and bevacizumab versus paclitaxel plus carboplatin and bevacizumab followed by maintenance bevacizumab in patients with stage IIIB or IV nonsquamous non-small-cell lung cancer. J Clin Oncol. 2013 Dec 01; 31(34):4349-57.
Patel JD, Socinski MA, Garon EB, Reynolds CH, Spigel DR, Olsen MR, Hermann RC, Jotte RM, Beck T, Richards DA, Guba SC, Liu J, Frimodt-Moller B, John WJ, Obasaju CK, Pennella EJ, Bonomi P, Govindan R. PMID: 24145346; PMCID: PMC4881367.
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PubMed Mentions:
165 Fields:
Translation:
HumansCTClinical Trials
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Phase 2 study of pemetrexed plus carboplatin, or pemetrexed plus cisplatin with concurrent radiation therapy followed by pemetrexed consolidation in patients with favorable-prognosis inoperable stage IIIA/B non-small-cell lung cancer. J Thorac Oncol. 2013 Oct; 8(10):1308-16.
Choy H, Schwartzberg LS, Dakhil SR, Garon EB, Gerber DE, Choksi JK, Govindan R, Peng G, Koustenis A, Treat J, Obasaju C. PMID: 23981966; PMCID: PMC4715866.
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PubMed Mentions:
14 Fields:
Translation:
HumansCTClinical Trials
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Elevated neutrophil gelatinase-associated lipocalin contributes to erlotinib resistance in non-small cell lung cancer. Am J Transl Res. 2013; 5(5):481-96.
Krysan K, Cui X, Gardner BK, Reckamp KL, Wang X, Hong L, Walser TC, Rodriguez NL, Pagano PC, Garon EB, Brothers JF, Elashoff D, Lee JM, Spira AE, Sharma S, Fishbein MC, Dubinett SM. PMID: 23977408; PMCID: PMC3745436.
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PubMed Mentions:
13
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Characteristics of lung cancers harboring NRAS mutations. Clin Cancer Res. 2013 May 01; 19(9):2584-91.
Ohashi K, Sequist LV, Arcila ME, Lovly CM, Chen X, Rudin CM, Moran T, Camidge DR, Vnencak-Jones CL, Berry L, Pan Y, Sasaki H, Engelman JA, Garon EB, Dubinett SM, Franklin WA, Riely GJ, Sos ML, Kris MG, Dias-Santagata D, Ladanyi M, Bunn PA, Pao W. PMID: 23515407; PMCID: PMC3643999.
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PubMed Mentions:
66 Fields:
Translation:
HumansCells
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The HSP90 inhibitor NVP-AUY922 potently inhibits non-small cell lung cancer growth. Mol Cancer Ther. 2013 Jun; 12(6):890-900.
Garon EB, Finn RS, Hamidi H, Dering J, Pitts S, Kamranpour N, Desai AJ, Hosmer W, Ide S, Avsar E, Jensen MR, Quadt C, Liu M, Dubinett SM, Slamon DJ. PMID: 23493311; PMCID: PMC3681857.
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PubMed Mentions:
36 Fields:
Translation:
HumansCells
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Antiestrogen fulvestrant enhances the antiproliferative effects of epidermal growth factor receptor inhibitors in human non-small-cell lung cancer. J Thorac Oncol. 2013 Mar; 8(3):270-8.
Garon EB, Pietras RJ, Finn RS, Kamranpour N, Pitts S, Márquez-Garbán DC, Desai AJ, Dering J, Hosmer W, von Euw EM, Dubinett SM, Slamon DJ. PMID: 23399957; PMCID: PMC3573351.
View in:
PubMed Mentions:
29 Fields:
Translation:
HumansCells
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Targeting MEK for the treatment of non-small-cell lung cancer. J Thorac Oncol. 2012 Dec; 7(16 Suppl 5):S377-8.
Goldman JW, Garon EB. PMID: 23160324; PMCID: PMC3741037.
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PubMed Mentions:
8 Fields:
Translation:
Humans
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Expanding options for EGFR targeting in lung cancer. Transl Lung Cancer Res. 2012 Dec; 1(4):287-8.
Chou T, Finn RS, Garon EB. PMID: 25806196; PMCID: PMC4367554.
View in:
PubMed Mentions:
2
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The role of estrogen, progesterone and aromatase in human non-small-cell lung cancer. Lung Cancer Manag. 2012 Dec; 1(4):259-272.
Kazmi N, Márquez-Garbán DC, Aivazyan L, Hamilton N, Garon EB, Goodglick L, Pietras RJ. PMID: 23650476; PMCID: PMC3643508.
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PubMed Mentions:
16
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Multicenter trial of EC145 in advanced, folate-receptor positive adenocarcinoma of the lung. J Thorac Oncol. 2012 Oct; 7(10):1618-21.
Edelman MJ, Harb WA, Pal SE, Boccia RV, Kraut MJ, Bonomi P, Conley BA, Rogers JS, Messmann RA, Garon EB. PMID: 22982661.
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PubMed Mentions:
17 Fields:
Translation:
Humans
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Uncertainty and psychological adjustment in patients with lung cancer. Psychooncology. 2013 Jun; 22(6):1396-401.
Kurita K, Garon EB, Stanton AL, Meyerowitz BE. PMID: 22887017; PMCID: PMC4036804.
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PubMed Mentions:
38 Fields:
Translation:
Humans
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A randomized, double-blind, phase III study of Docetaxel and Ramucirumab versus Docetaxel and placebo in the treatment of stage IV non-small-cell lung cancer after disease progression after 1 previous platinum-based therapy (REVEL): treatment rationale and study design. Clin Lung Cancer. 2012 Nov; 13(6):505-9.
Garon EB, Cao D, Alexandris E, John WJ, Yurasov S, Perol M. PMID: 22853980.
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PubMed Mentions:
17 Fields:
Translation:
HumansCTClinical Trials
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Issues surrounding clinical trial endpoints in solid malignancies with a focus on metastatic non-small cell lung cancer. Lung Cancer. 2012 Sep; 77(3):475-81.
Garon EB. PMID: 22795702; PMCID: PMC3737740.
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PubMed Mentions:
8 Fields:
Translation:
Humans
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Development of transcriptomic biomarker signature in human saliva to detect lung cancer. Cell Mol Life Sci. 2012 Oct; 69(19):3341-3350.
Zhang L, Xiao H, Zhou H, Santiago S, Lee JM, Garon EB, Yang J, Brinkmann O, Yan X, Akin D, Chia D, Elashoff D, Park NH, Wong DTW. PMID: 22689099; PMCID: PMC4121486.
View in:
PubMed Mentions:
81 Fields:
Translation:
HumansCells
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Phase II study of single-agent navitoclax (ABT-263) and biomarker correlates in patients with relapsed small cell lung cancer. Clin Cancer Res. 2012 Jun 01; 18(11):3163-9.
Rudin CM, Hann CL, Garon EB, Ribeiro de Oliveira M, Bonomi PD, Camidge DR, Chu Q, Giaccone G, Khaira D, Ramalingam SS, Ranson MR, Dive C, McKeegan EM, Chyla BJ, Dowell BL, Chakravartty A, Nolan CE, Rudersdorf N, Busman TA, Mabry MH, Krivoshik AP, Humerickhouse RA, Shapiro GI, Gandhi L. PMID: 22496272; PMCID: PMC3715059.
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PubMed Mentions:
275 Fields:
Translation:
HumansCTClinical Trials
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Proteomic analysis of human saliva from lung cancer patients using two-dimensional difference gel electrophoresis and mass spectrometry. Mol Cell Proteomics. 2012 Feb; 11(2):M111.012112.
Xiao H, Zhang L, Zhou H, Lee JM, Garon EB, Wong DT. PMID: 22096114; PMCID: PMC3277759.
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PubMed Mentions:
74 Fields:
Translation:
HumansCells
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(18)F-FDG PET/CT for monitoring treatment responses to the epidermal growth factor receptor inhibitor erlotinib. J Nucl Med. 2011 Nov; 52(11):1684-1689.
Benz MR, Herrmann K, Walter F, Garon EB, Reckamp KL, Figlin R, Phelps ME, Weber WA, Czernin J, Allen-Auerbach MS. PMID: 22045706; PMCID: PMC5021512.
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PubMed Mentions:
40 Fields:
Translation:
HumansCTClinical Trials
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Mitotic inhibitors. J Thorac Oncol. 2011 Nov; 6(11 Suppl 4):S1791-2.
Garon EB, Dubinett SM. PMID: 22005532; PMCID: PMC3812544.
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PubMed Mentions: Fields:
Translation:
Humans
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Downstaging chemotherapy and alteration in the classic computed tomography/magnetic resonance imaging signs of vascular involvement in patients with pancreaticobiliary malignant tumors: influence on patient selection for surgery. Arch Surg. 2011 Jul; 146(7):836-43.
Donahue TR, Isacoff WH, Hines OJ, Tomlinson JS, Farrell JJ, Bhat YM, Garon E, Clerkin B, Reber HA. PMID: 21768431.
View in:
PubMed Mentions:
27 Fields:
Translation:
Humans
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Progesterone and estrogen receptor expression and activity in human non-small cell lung cancer. Steroids. 2011 Aug; 76(9):910-20.
Marquez-Garban DC, Mah V, Alavi M, Maresh EL, Chen HW, Bagryanova L, Horvath S, Chia D, Garon E, Goodglick L, Pietras RJ. PMID: 21600232; PMCID: PMC3129425.
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PubMed Mentions:
40 Fields:
Translation:
HumansAnimalsCells
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The new staging system for lung cancer: imaging and clinical implications. J Thorac Imaging. 2011 May; 26(2):119-31.
Greaves SM, Brown K, Garon EB, Garon BL. PMID: 21508734.
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PubMed Mentions:
4 Fields:
Translation:
Humans
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High prevalence of lung cancer in a surgical cohort of lung cancer patients a decade after smoking cessation. J Cardiothorac Surg. 2011 Feb 25; 6:19.
Mong C, Garon EB, Fuller C, Mahtabifard A, Mirocha J, Mosenifar Z, McKenna R. PMID: 21352550; PMCID: PMC3056729.
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PubMed Mentions:
7 Fields:
Translation:
Humans
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Phase I dose-escalation study of the pan-HER inhibitor, PF299804, in patients with advanced malignant solid tumors. Clin Cancer Res. 2011 Mar 01; 17(5):1131-9.
Jänne PA, Boss DS, Camidge DR, Britten CD, Engelman JA, Garon EB, Guo F, Wong S, Liang J, Letrent S, Millham R, Taylor I, Eckhardt SG, Schellens JH. PMID: 21220471; PMCID: PMC3048920.
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PubMed Mentions:
82 Fields:
Translation:
HumansCellsCTClinical Trials
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Poly(ADP-ribose) polymerase inhibitors. J Thorac Oncol. 2010 Dec; 5(12 Suppl 6):S455-6.
Garon EB, Dubinett SM. PMID: 21102236.
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PubMed Mentions:
1 Fields:
Translation:
Humans
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Novel drugs--miscellaneous category. J Thorac Oncol. 2010 Dec; 5(12 Suppl 6):S468-9.
Hosmer WD, Dubinett SM, Garon EB. PMID: 21102242.
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PubMed Mentions: Fields:
Translation:
Humans
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Proapoptotic agents in lung cancer. J Thorac Oncol. 2010 Dec; 5(12 Suppl 6):S480-1.
Ujhazy P, Garon EB. PMID: 21102248.
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PubMed Mentions: Fields:
Translation:
Humans
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Management of small-cell lung cancer: time to move forward. Oncology (Williston Park). 2010 Oct; 24(11):1043, 1046-7.
Pollock J, Garon EB. PMID: 21155456.
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PubMed Mentions: Fields:
Translation:
Humans
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Identification of common predictive markers of in vitro response to the Mek inhibitor selumetinib (AZD6244; ARRY-142886) in human breast cancer and non-small cell lung cancer cell lines. Mol Cancer Ther. 2010 Jul; 9(7):1985-94.
Garon EB, Finn RS, Hosmer W, Dering J, Ginther C, Adhami S, Kamranpour N, Pitts S, Desai A, Elashoff D, French T, Smith P, Slamon DJ. PMID: 20587667; PMCID: PMC2939826.
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PubMed Mentions:
35 Fields:
Translation:
HumansCells
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Intracellular signaling molecules. J Thorac Oncol. 2009 Nov; 4(11 Suppl 3):S1057-8.
Garon EB, Dubinett SM. PMID: 19861915.
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PubMed Mentions: Fields:
Translation:
HumansCells
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Inflammation, epithelial to mesenchymal transition, and epidermal growth factor receptor tyrosine kinase inhibitor resistance. J Thorac Oncol. 2008 Feb; 3(2):107-10.
Krysan K, Lee JM, Dohadwala M, Gardner BK, Reckamp KL, Garon E, St John M, Sharma S, Dubinett SM. PMID: 18303428.
View in:
PubMed Mentions:
21 Fields:
Translation:
HumansCells
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Inflammation and lung carcinogenesis: applying findings in prevention and treatment. Expert Rev Anticancer Ther. 2007 Oct; 7(10):1405-21.
Peebles KA, Lee JM, Mao JT, Hazra S, Reckamp KL, Krysan K, Dohadwala M, Heinrich EL, Walser TC, Cui X, Baratelli FE, Garon E, Sharma S, Dubinett SM. PMID: 17944566.
View in:
PubMed Mentions:
36 Fields:
Translation:
HumansAnimals
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In vitro and in vivo evaluation and a case report of intense nanosecond pulsed electric field as a local therapy for human malignancies. Int J Cancer. 2007 Aug 01; 121(3):675-82.
Garon EB, Sawcer D, Vernier PT, Tang T, Sun Y, Marcu L, Gundersen MA, Koeffler HP. PMID: 17417774.
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PubMed Mentions:
52 Fields:
Translation:
HumansAnimalsCells
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Quantum dot labeling and tracking of human leukemic, bone marrow and cord blood cells. Leuk Res. 2007 May; 31(5):643-51.
Garon EB, Marcu L, Luong Q, Tcherniantchouk O, Crooks GM, Koeffler HP. PMID: 17027955; PMCID: PMC8761484.
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PubMed Mentions:
6 Fields:
Translation:
HumansCells
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Nanoelectropulse intracellular perturbation and electropermeabilization technology: phospholipid translocation, calcium bursts, chromatin rearrangement, cardiomyocyte activation, and tumor cell sensitivity. Conf Proc IEEE Eng Med Biol Soc. 2005; 2005:5850-3.
Vernier PT, Sun Y, Wang J, Thu MM, Garon E, Valderrabano M, Marcu L, Koeffler HP, Gundersen MA. PMID: 17281590.
View in:
PubMed Mentions:
8 Fields: