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Characteristics of a CCL21-gene modified dendritic cell vaccine utilized for a clinical trial in non-small cell lung cancer. Mol Cancer Ther. 2024 Nov 19.
Oh MS, Dumitras C, Salehi-Rad R, Tran LM, Krysan K, Lim RJ, Jing Z, Tappuni S, Lisberg A, Garon EB, Dubinett SM, Liu B. PMID: 39559833.
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PubMed Mentions: Fields:
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Premalignant Progression in the Lung: Knowledge Gaps and Novel Opportunities for Interception of Non-Small Cell Lung Cancer. An Official American Thoracic Society Research Statement. Am J Respir Crit Care Med. 2024 Sep 01; 210(5):548-571.
Moghaddam SJ, Savai R, Salehi-Rad R, Sengupta S, Kammer MN, Massion P, Beane JE, Ostrin EJ, Priolo C, Tennis MA, Stabile LP, Bauer AK, Sears CR, Szabo E, Rivera MP, Powell CA, Kadara H, Jenkins BJ, Dubinett SM, Houghton AM, Kim CF, Keith RL. PMID: 39115548; PMCID: PMC11389570.
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PubMed Mentions: Fields:
Translation:
Humans
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Noninvasive Lung Cancer Subtype Classification Using Tumor-Derived Signatures and cfDNA Methylome. Cancer Res Commun. 2024 Jul 01; 4(7):1738-1747.
Li S, Li W, Liu B, Krysan K, Dubinett SM. PMID: 38856716; PMCID: PMC11249519.
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PubMed Mentions: Fields:
Translation:
HumansCells
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Expression of Concern: Durable Suppression of Acquired MEK Inhibitor Resistance in Cancer by Sequestering MEK from ERK and Promoting Antitumor T-cell Immunity. Cancer Discov. 2024 07 01; 14(7):1357.
Hong A, Piva M, Liu S, Hugo W, Lomeli SH, Zoete V, Randolph CE, Yang Z, Wang Y, Lee JJ, Lo SJ, Sun L, Vega-Crespo A, Garcia AJ, Shackelford DB, Dubinett SM, Scumpia PO, Byrum SD, Tackett AJ, Donahue TR, Michielin O, Holmen SL, Ribas A, Moriceau G, Lo RS. PMID: 38946326.
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PubMed Mentions: Fields:
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Single-stranded pre-methylated 5mC adapters uncover the methylation profile of plasma ultrashort Single-stranded cell-free DNA. Nucleic Acids Res. 2024 Jun 24; 52(11):e50.
Cheng JC, Swarup N, Morselli M, Huang WL, Aziz M, Caggiano C, Kordi M, Patel AA, Chia D, Kim Y, Li F, Wei F, Zaitlen N, Krysan K, Dubinett S, Pellegrini M, Wong DTW. PMID: 38797520; PMCID: PMC11194076.
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PubMed Mentions:
1 Fields:
Translation:
HumansCells
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Opposing tumor-cell-intrinsic and -extrinsic roles of the IRF1 transcription factor in antitumor immunity. Cell Rep. 2024 Jun 25; 43(6):114289.
Purbey PK, Seo J, Paul MK, Iwamoto KS, Daly AE, Feng AC, Champhekar AS, Langerman J, Campbell KM, Schaue D, McBride WH, Dubinett SM, Ribas A, Smale ST, Scumpia PO. PMID: 38833371; PMCID: PMC11315447.
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PubMed Mentions:
3 Fields:
Translation:
HumansAnimalsCells
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The evolution of lung adenocarcinoma precursors is associated with chromosomal instability and transition from innate to adaptive immune response/evasion. Res Sq. 2024 May 15.
Hu X, Zhu B, Vokes N, Fujimoto J, Rojas Alvarez FR, Heeke S, Moreira AL, Solis LM, Haymaker C, Velcheti V, Sterman DH, Pass HI, Cheng C, Lee JJ, Zhang J, Wei Z, Wu J, Le X, Ostrin E, Toumazis I, Gibbons D, Su D, Fukuoka J, Antonoff MB, Gerber DE, Li C, Kadara H, Wang L, Davis M, Heymach JV, Hannash S, Wistuba I, Dubinett S, Alexandrov L, Lippman S, Spira A, Futreal AP, Reuben A, Zhang J. PMID: 38798564; PMCID: PMC11118701.
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PubMed Mentions:
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Author Correction: Cost-effective methylome sequencing of cell-free DNA for accurately detecting and locating cancer. Nat Commun. 2024 May 01; 15(1):3693.
Stackpole ML, Zeng W, Li S, Liu CC, Zhou Y, He S, Yeh A, Wang Z, Sun F, Li Q, Yuan Z, Yildirim A, Chen PJ, Winograd P, Tran B, Lee YT, Li PS, Noor Z, Yokomizo M, Ahuja P, Zhu Y, Tseng HR, Tomlinson JS, Garon E, French S, Magyar CE, Dry S, Lajonchere C, Geschwind D, Choi G, Saab S, Alber F, Wong WH, Dubinett SM, Aberle DR, Agopian V, Han SB, Ni X, Li W, Zhou XJ. PMID: 38693151; PMCID: PMC11063198.
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PubMed Mentions: Fields:
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Author Correction: An atlas of epithelial cell states and plasticity in lung adenocarcinoma. Nature. 2024 Apr; 628(8006):E1.
Han G, Sinjab A, Rahal Z, Lynch AM, Treekitkarnmongkol W, Liu Y, Serrano AG, Feng J, Liang K, Khan K, Lu W, Hernandez SD, Liu Y, Cao X, Dai E, Pei G, Hu J, Abaya C, Gomez-Bolanos LI, Peng F, Chen M, Parra ER, Cascone T, Sepesi B, Moghaddam SJ, Scheet P, Negrao MV, Heymach JV, Li M, Dubinett SM, Stevenson CS, Spira AE, Fujimoto J, Solis LM, Wistuba II, Chen J, Wang L, Kadara H. PMID: 38499683; PMCID: PMC10990920.
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PubMed Mentions: Fields:
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CXCL9/10-engineered dendritic cells promote T cell activation and enhance immune checkpoint blockade for lung cancer. Cell Rep Med. 2024 Apr 16; 5(4):101479.
Lim RJ, Salehi-Rad R, Tran LM, Oh MS, Dumitras C, Crosson WP, Li R, Patel TS, Man S, Yean CE, Abascal J, Huang Z, Ong SL, Krysan K, Dubinett SM, Liu B. PMID: 38518770; PMCID: PMC11031384.
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PubMed Mentions:
5 Fields:
Translation:
HumansAnimalsCells
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An atlas of epithelial cell states and plasticity in lung adenocarcinoma. Nature. 2024 Mar; 627(8004):656-663.
Han G, Sinjab A, Rahal Z, Lynch AM, Treekitkarnmongkol W, Liu Y, Serrano AG, Feng J, Liang K, Khan K, Lu W, Hernandez SD, Liu Y, Cao X, Dai E, Pei G, Hu J, Abaya C, Gomez-Bolanos LI, Peng F, Chen M, Parra ER, Cascone T, Sepesi B, Moghaddam SJ, Scheet P, Negrao MV, Heymach JV, Li M, Dubinett SM, Stevenson CS, Spira AE, Fujimoto J, Solis LM, Wistuba II, Chen J, Wang L, Kadara H. PMID: 38418883; PMCID: PMC10954546.
View in:
PubMed Mentions:
18 Fields:
Translation:
HumansAnimalsCells
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Glucose Deprivation Promotes Pseudohypoxia and Dedifferentiation in Lung Adenocarcinoma. Cancer Res. 2024 01 16; 84(2):305-327.
Saggese P, Pandey A, Alcaraz M, Fung E, Hall A, Yanagawa J, Rodriguez EF, Grogan TR, Giurato G, Nassa G, Salvati A, Shirihai OS, Weisz A, Dubinett SM, Scafoglio C. PMID: 37934116; PMCID: PMC10790128.
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PubMed Mentions:
2 Fields:
Translation:
HumansAnimals
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Dendritic Cell Vaccination in Non-Small Cell Lung Cancer: Remodeling the Tumor Immune Microenvironment. Cells. 2023 10 04; 12(19).
Abascal J, Oh MS, Liclican EL, Dubinett SM, Salehi-Rad R, Liu B. PMID: 37830618; PMCID: PMC10571973.
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PubMed Mentions:
4 Fields:
Translation:
HumansCellsPHPublic Health
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Single-Cell Characterization of Pulmonary Nodules Implicates Suppression of Immunosurveillance across Early Stages of Lung Adenocarcinoma. Cancer Res. 2023 10 02; 83(19):3305-3319.
Yanagawa J, Tran LM, Salehi-Rad R, Lim RJ, Dumitras C, Fung E, Wallace WD, Prosper AE, Fishbein G, Shea C, Hong R, Kahangi B, Deng JJ, Gower AC, Liu B, Campbell JD, Mazzilli SA, Beane JE, Kadara H, Lenburg ME, Spira AE, Aberle DR, Krysan K, Dubinett SM. PMID: 37477508; PMCID: PMC10544016.
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PubMed Mentions:
5 Fields:
Translation:
Humans
-
CCL21-DC in situ vaccination in murine NSCLC overcomes resistance to immunotherapy and generates systemic tumor-specific immunity. J Immunother Cancer. 2023 09; 11(9).
Salehi-Rad R, Lim RJ, Du Y, Tran LM, Li R, Ong SL, Ling Huang Z, Dumitras C, Zhang T, Park SJ, Crosson W, Kahangi B, Abascal J, Seet C, Oh M, Shabihkhani M, Paul M, Krysan K, Lisberg AE, Garon EB, Liu B, Dubinett SM. PMID: 37730274; PMCID: PMC10510892.
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PubMed Mentions:
3 Fields:
Translation:
HumansAnimals
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Comprehensive tissue deconvolution of cell-free DNA by deep learning for disease diagnosis and monitoring. Proc Natl Acad Sci U S A. 2023 07 11; 120(28):e2305236120.
Li S, Zeng W, Ni X, Liu Q, Li W, Stackpole ML, Zhou Y, Gower A, Krysan K, Ahuja P, Lu DS, Raman SS, Hsu W, Aberle DR, Magyar CE, French SW, Han SB, Garon EB, Agopian VG, Wong WH, Dubinett SM, Zhou XJ. PMID: 37399400; PMCID: PMC10334733.
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PubMed Mentions:
10 Fields:
Translation:
HumansCells
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Multi-organ landscape of therapy-resistant melanoma. Nat Med. 2023 05; 29(5):1123-1134.
Liu S, Dharanipragada P, Lomeli SH, Wang Y, Zhang X, Yang Z, Lim RJ, Dumitras C, Scumpia PO, Dubinett SM, Moriceau G, Johnson DB, Moschos SJ, Lo RS. PMID: 37106167; PMCID: PMC10202813.
View in:
PubMed Mentions:
9 Fields:
Translation:
HumansCells
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Tumor heterogeneity in VHL drives metastasis in clear cell renal cell carcinoma. Signal Transduct Target Ther. 2023 04 17; 8(1):155.
Hu J, Tan P, Ishihara M, Bayley NA, Schokrpur S, Reynoso JG, Zhang Y, Lim RJ, Dumitras C, Yang L, Dubinett SM, Jat PS, Van Snick J, Huang J, Chin AI, Prins RM, Graeber TG, Xu H, Wu L. PMID: 37069149; PMCID: PMC10110583.
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PubMed Mentions:
13 Fields:
Translation:
Humans
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Tumoral Densities of T-Cells and Mast Cells Are Associated With Recurrence in Early-Stage Lung Adenocarcinoma. JTO Clin Res Rep. 2023 Sep; 4(9):100504.
Kammer MN, Mori H, Rowe DJ, Chen SC, Vasiukov G, Atwater T, Senosain MF, Antic S, Zou Y, Chen H, Peikert T, Deppen S, Grogan EL, Massion PP, Dubinett S, Lenburg M, Borowsky A, Maldonado F. PMID: 37674811; PMCID: PMC10477685.
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PubMed Mentions:
1
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Spatial mapping of mitochondrial networks and bioenergetics in lung cancer. Nature. 2023 03; 615(7953):712-719.
Han M, Bushong EA, Segawa M, Tiard A, Wong A, Brady MR, Momcilovic M, Wolf DM, Zhang R, Petcherski A, Madany M, Xu S, Lee JT, Poyurovsky MV, Olszewski K, Holloway T, Gomez A, John MS, Dubinett SM, Koehler CM, Shirihai OS, Stiles L, Lisberg A, Soatto S, Sadeghi S, Ellisman MH, Shackelford DB. PMID: 36922590; PMCID: PMC10033418.
View in:
PubMed Mentions:
33 Fields:
Translation:
HumansCells
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Glucose deprivation promotes pseudo-hypoxia and de-differentiation in lung adenocarcinoma. bioRxiv. 2023 Feb 01.
Saggese P, Pandey A, Fung E, Hall A, Yanagawa J, Rodriguez EF, Grogan TR, Giurato G, Nassa G, Salvati A, Weisz A, Dubinett SM, Scafoglio C. PMID: 36778362; PMCID: PMC9915520.
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PubMed Mentions:
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The Single-Cell Immunogenomic Landscape of B and Plasma Cells in Early-Stage Lung Adenocarcinoma. Cancer Discov. 2022 11 02; 12(11):2626-2645.
Hao D, Han G, Sinjab A, Gomez-Bolanos LI, Lazcano R, Serrano A, Hernandez SD, Dai E, Cao X, Hu J, Dang M, Wang R, Chu Y, Song X, Zhang J, Parra ER, Wargo JA, Swisher SG, Cascone T, Sepesi B, Futreal AP, Li M, Dubinett SM, Fujimoto J, Solis Soto LM, Wistuba II, Stevenson CS, Spira A, Shalapour S, Kadara H, Wang L. PMID: 36098652; PMCID: PMC9633381.
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PubMed Mentions:
31 Fields:
Translation:
HumansCells
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Cost-effective methylome sequencing of cell-free DNA for accurately detecting and locating cancer. Nat Commun. 2022 09 29; 13(1):5566.
Stackpole ML, Zeng W, Li S, Liu CC, Zhou Y, He S, Yeh A, Wang Z, Sun F, Li Q, Yuan Z, Yildirim A, Chen PJ, Winograd P, Tran B, Lee YT, Li PS, Noor Z, Yokomizo M, Ahuja P, Zhu Y, Tseng HR, Tomlinson JS, Garon E, French S, Magyar CE, Dry S, Lajonchere C, Geschwind D, Choi G, Saab S, Alber F, Wong WH, Dubinett SM, Aberle DR, Agopian V, Han SB, Ni X, Li W, Zhou XJ. PMID: 36175411; PMCID: PMC9522828.
View in:
PubMed Mentions:
26 Fields:
Translation:
Humans
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Targeting EZH2 to overcome the resistance to immunotherapy in lung cancer. Semin Oncol. 2022 Jun; 49(3-4):306-318.
Shin DS, Park K, Garon E, Dubinett S. PMID: 35851153.
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PubMed Mentions:
5 Fields:
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cfTrack: A Method of Exome-Wide Mutation Analysis of Cell-free DNA to Simultaneously Monitor the Full Spectrum of Cancer Treatment Outcomes Including MRD, Recurrence, and Evolution. Clin Cancer Res. 2022 05 02; 28(9):1841-1853.
Li S, Zeng W, Ni X, Zhou Y, Stackpole ML, Noor ZS, Yuan Z, Neal A, Memarzadeh S, Garon EB, Dubinett SM, Li W, Zhou XJ. PMID: 35149536; PMCID: PMC9126584.
View in:
PubMed Mentions:
4 Fields:
Translation:
Humans
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Statistical parametrization of cell cytoskeleton reveals lung cancer cytoskeletal phenotype with partial EMT signature. Commun Biol. 2022 05 02; 5(1):407.
Basu A, Paul MK, Alioscha-Perez M, Grosberg A, Sahli H, Dubinett SM, Weiss S. PMID: 35501466; PMCID: PMC9061773.
View in:
PubMed Mentions:
7 Translation:
HumansCells
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Society for Immunotherapy of Cancer (SITC) clinical practice guideline on immunotherapy for the treatment of lung cancer and mesothelioma. J Immunother Cancer. 2022 05; 10(5).
Govindan R, Aggarwal C, Antonia SJ, Davies M, Dubinett SM, Ferris A, Forde PM, Garon EB, Goldberg SB, Hassan R, Hellmann MD, Hirsch FR, Johnson ML, Malik S, Morgensztern D, Neal JW, Patel JD, Rimm DL, Sagorsky S, Schwartz LH, Sepesi B, Herbst RS. PMID: 35640927; PMCID: PMC9157337.
View in:
PubMed Mentions:
14 Fields:
Translation:
Humans
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Response and recurrence correlates in individuals treated with neoadjuvant anti-PD-1 therapy for resectable oral cavity squamous cell carcinoma. Cell Rep Med. 2021 10 19; 2(10):100411.
Liu S, Knochelmann HM, Lomeli SH, Hong A, Richardson M, Yang Z, Lim RJ, Wang Y, Dumitras C, Krysan K, Timmers C, Romeo MJ, Krieg C, O'Quinn EC, Horton JD, Dubinett SM, Paulos CM, Neskey DM, Lo RS. PMID: 34755131; PMCID: PMC8561238.
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PubMed Mentions:
20 Fields:
Translation:
HumansCellsCTClinical Trials
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Technical Feasibility and Safety of Repeated Computed Tomography-Guided Transthoracic Intratumoral Injection of Gene-Modified Cellular Immunotherapy in Metastatic NSCLC. JTO Clin Res Rep. 2021 Nov; 2(11):100242.
Shahrouki P, Lee JM, Barclay J, Khan SN, Genshaft S, Abtin F, Dubinett SM, Lisberg A, Sharma S, Garon EB, Suh R. PMID: 34806054; PMCID: PMC8581369.
View in:
PubMed Mentions:
1
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Early Diagnosis and Screening for Lung Cancer. Cold Spring Harb Perspect Med. 2021 09 01; 11(9).
Kadara H, Tran LM, Liu B, Vachani A, Li S, Sinjab A, Zhou XJ, Dubinett SM, Krysan K. PMID: 34001525; PMCID: PMC8415293.
View in:
PubMed Mentions:
15 Fields:
Translation:
HumansCellsPHPublic Health
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COVID-19 Vaccine Decision-making Factors in Racial and Ethnic Minority Communities in Los Angeles, California. JAMA Netw Open. 2021 09 01; 4(9):e2127582.
Carson SL, Casillas A, Castellon-Lopez Y, Mansfield LN, Morris D, Barron J, Ntekume E, Landovitz R, Vassar SD, Norris KC, Dubinett SM, Garrison NA, Brown AF. PMID: 34591103; PMCID: PMC8485164.
View in:
PubMed Mentions:
83 Fields:
Translation:
Humans
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Genotoxic Treatment Enhances Immune Response in a Genetic Model of Lung Cancer. Cancers (Basel). 2021 Jul 18; 13(14).
Saggese P, Martinez CA, Tran LM, Lim R, Dumitras C, Grogan T, Elashoff D, Ramin SR, Dubinett SM, Liu B, Scafoglio C. PMID: 34298808; PMCID: PMC8307650.
View in:
PubMed Mentions:
1
-
Sensitive detection of tumor mutations from blood and its application to immunotherapy prognosis. Nat Commun. 2021 07 07; 12(1):4172.
Li S, Noor ZS, Zeng W, Stackpole ML, Ni X, Zhou Y, Yuan Z, Wong WH, Agopian VG, Dubinett SM, Alber F, Li W, Garon EB, Zhou XJ. PMID: 34234141; PMCID: PMC8263778.
View in:
PubMed Mentions:
15 Fields:
Translation:
HumansCTClinical Trials
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Immune evasion in HPV- head and neck precancer-cancer transition is driven by an aneuploid switch involving chromosome 9p loss. Proc Natl Acad Sci U S A. 2021 05 11; 118(19).
William WN, Zhao X, Bianchi JJ, Lin HY, Cheng P, Lee JJ, Carter H, Alexandrov LB, Abraham JP, Spetzler DB, Dubinett SM, Cleveland DW, Cavenee W, Davoli T, Lippman SM. PMID: 33952700; PMCID: PMC8126856.
View in:
PubMed Mentions:
33 Fields:
Translation:
HumansCells
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Resolving the Spatial and Cellular Architecture of Lung Adenocarcinoma by Multiregion Single-Cell Sequencing. Cancer Discov. 2021 10; 11(10):2506-2523.
Sinjab A, Han G, Treekitkarnmongkol W, Hara K, Brennan PM, Dang M, Hao D, Wang R, Dai E, Dejima H, Zhang J, Bogatenkova E, Sanchez-Espiridion B, Chang K, Little DR, Bazzi S, Tran LM, Krysan K, Behrens C, Duose DY, Parra ER, Raso MG, Solis LM, Fukuoka J, Zhang J, Sepesi B, Cascone T, Byers LA, Gibbons DL, Chen J, Moghaddam SJ, Ostrin EJ, Rosen D, Heymach JV, Scheet P, Dubinett SM, Fujimoto J, Wistuba II, Stevenson CS, Spira A, Wang L, Kadara H. PMID: 33972311; PMCID: PMC8487926.
View in:
PubMed Mentions:
51 Fields:
Translation:
HumansCells
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Inhibition of Granulocytic Myeloid-Derived Suppressor Cells Overcomes Resistance to Immune Checkpoint Inhibition in LKB1-Deficient Non-Small Cell Lung Cancer. Cancer Res. 2021 06 15; 81(12):3295-3308.
Li R, Salehi-Rad R, Crosson W, Momcilovic M, Lim RJ, Ong SL, Huang ZL, Zhang T, Abascal J, Dumitras C, Jing Z, Park SJ, Krysan K, Shackelford DB, Tran LM, Liu B, Dubinett SM. PMID: 33853830; PMCID: PMC8776246.
View in:
PubMed Mentions:
43 Fields:
Translation:
HumansAnimalsCells
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Challenges and lessons learned for institutional review board procedures during the COVID-19 pandemic. J Clin Transl Sci. 2021 Mar 16; 5(1):e107.
Ford DE, Johnson A, Nichols JJ, Rothwell E, Dubinett S, Naeim A. PMID: 34192061; PMCID: PMC8220014.
View in:
PubMed Mentions:
7
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Single-Cell Expression Landscape of SARS-CoV-2 Receptor ACE2 and Host Proteases in Normal and Malignant Lung Tissues from Pulmonary Adenocarcinoma Patients. Cancers (Basel). 2021 Mar 12; 13(6).
Han G, Sinjab A, Hara K, Treekitkarnmongkol W, Brennan P, Chang K, Bogatenkova E, Sanchez-Espiridion B, Behrens C, Solis LM, Gao B, Girard L, Zhang J, Sepesi B, Cascone T, Byers LA, Gibbons DL, Chen J, Moghaddam SJ, Ostrin EJ, Scheet P, Fujimoto J, Shay J, Heymach JV, Minna JD, Dubinett S, Wistuba II, Stevenson CS, Spira AE, Wang L, Kadara H. PMID: 33809063; PMCID: PMC7998226.
View in:
PubMed Mentions:
4
-
Investigation of Combination Treatment With an Aromatase Inhibitor Exemestane and Carboplatin-Based Therapy for Postmenopausal Women With Advanced NSCLC. JTO Clin Res Rep. 2021 Apr; 2(4):100150.
Young PA, Márquez-Garbán DC, Noor ZS, Moatamed N, Elashoff D, Grogan T, Romero T, Sasano H, Saito R, Rausch R, Hamilton N, Dubinett SM, Garon EB, Pietras RJ. PMID: 34590007; PMCID: PMC8474426.
View in:
PubMed Mentions:
3
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Novel Kras-mutant murine models of non-small cell lung cancer possessing co-occurring oncogenic mutations and increased tumor mutational burden. Cancer Immunol Immunother. 2021 Aug; 70(8):2389-2400.
Salehi-Rad R, Li R, Tran LM, Lim RJ, Abascal J, Momcilovic M, Park SJ, Ong SL, Shabihkhani M, Huang ZL, Paul M, Shackelford DB, Krysan K, Liu B, Dubinett SM. PMID: 33507343; PMCID: PMC8289771.
View in:
PubMed Mentions:
12 Fields:
Translation:
AnimalsCells
-
Durable Suppression of Acquired MEK Inhibitor Resistance in Cancer by Sequestering MEK from ERK and Promoting Antitumor T-cell Immunity. Cancer Discov. 2021 03; 11(3):714-735.
Hong A, Piva M, Liu S, Hugo W, Lomeli SH, Zoete V, Randolph CE, Yang Z, Wang Y, Lee JJ, Lo SJ, Sun L, Vega-Crespo A, Garcia AJ, Shackelford DB, Dubinett SM, Scumpia PO, Byrum SD, Tackett AJ, Donahue TR, Michielin O, Holmen SL, Ribas A, Moriceau G, Lo RS. PMID: 33318037; PMCID: PMC7933113.
View in:
PubMed Mentions:
31 Fields:
Translation:
HumansAnimalsCells
-
Mutational landscape influences immunotherapy outcomes among patients with non-small-cell lung cancer with human leukocyte antigen supertype B44. Nat Cancer. 2020 12; 1(12):1167-1175.
Cummings AL, Gukasyan J, Lu HY, Grogan T, Sunga G, Fares CM, Hornstein N, Zaretsky J, Carroll J, Bachrach B, Akingbemi WO, Li D, Noor Z, Lisberg A, Goldman JW, Elashoff D, Bui AAT, Ribas A, Dubinett SM, Rossetti M, Garon EB. PMID: 35121931.
View in:
PubMed Mentions:
18 Fields:
Translation:
Humans
-
Immunosurveillance and Regression in the Context of Squamous Pulmonary Premalignancy. Cancer Discov. 2020 10; 10(10):1442-1444.
Krysan K, Tran LM, Dubinett SM. PMID: 33004476; PMCID: PMC8396076.
View in:
PubMed Mentions:
2 Fields:
Translation:
HumansCells
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Occult Colonic Perforation in a Patient With Coronavirus Disease 2019 After Interleukin-6 Receptor Antagonist Therapy. Open Forum Infect Dis. 2020 Nov; 7(11):ofaa424.
Schwab K, Hamidi S, Chung A, Lim RJ, Khanlou N, Hoesterey D, Dumitras C, Adeyiga OB, Phan-Tang M, Wang TS, Saggar R, Goldstein J, Belperio JA, Dubinett SM, Kim JT, Salehi-Rad R. PMID: 33204749; PMCID: PMC7543619.
View in:
PubMed Mentions:
4
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Organoids Model Transcriptional Hallmarks of Oncogenic KRAS Activation in Lung Epithelial Progenitor Cells. Cell Stem Cell. 2020 10 01; 27(4):663-678.e8.
Dost AFM, Moye AL, Vedaie M, Tran LM, Fung E, Heinze D, Villacorta-Martin C, Huang J, Hekman R, Kwan JH, Blum BC, Louie SM, Rowbotham SP, Sainz de Aja J, Piper ME, Bhetariya PJ, Bronson RT, Emili A, Mostoslavsky G, Fishbein GA, Wallace WD, Krysan K, Dubinett SM, Yanagawa J, Kotton DN, Kim CF. PMID: 32891189; PMCID: PMC7541765.
View in:
PubMed Mentions:
68 Fields:
Translation:
HumansAnimalsCells
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Lung Cancer and Immunity Markers. Cancer Epidemiol Biomarkers Prev. 2020 12; 29(12):2423-2430.
Lim RJ, Liu B, Krysan K, Dubinett SM. PMID: 32856614; PMCID: PMC8294063.
View in:
PubMed Mentions:
6 Fields:
Translation:
Humans
-
Readmission Rates for Chronic Obstructive Pulmonary Disease Under the Hospital Readmissions Reduction Program: an Interrupted Time Series Analysis. J Gen Intern Med. 2020 12; 35(12):3581-3590.
Buhr RG, Jackson NJ, Kominski GF, Dubinett SM, Mangione CM, Ong MK. PMID: 32556878; PMCID: PMC7728926.
View in:
PubMed Mentions:
7 Fields:
Translation:
Humans
-
Author Correction: Chronic IL-1β-induced inflammation regulates epithelial-to-mesenchymal transition memory phenotypes via epigenetic modifications in non-small cell lung cancer. Sci Rep. 2020 Mar 04; 10(1):4386.
Li R, Ong SL, Tran LM, Jing Z, Liu B, Park SJ, Huang ZL, Walser TC, Heinrich EL, Lee G, Salehi-Rad R, Crosson WP, Pagano PC, Paul MK, Xu S, Herschman H, Krysan K, Dubinett S. PMID: 32127587; PMCID: PMC7054550.
View in:
PubMed Mentions:
4 Fields:
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The Biology of Lung Cancer: Development of More Effective Methods for Prevention, Diagnosis, and Treatment. Clin Chest Med. 2020 03; 41(1):25-38.
Salehi-Rad R, Li R, Paul MK, Dubinett SM, Liu B. PMID: 32008627.
View in:
PubMed Mentions:
35 Fields:
Translation:
Humans
-
FRA1 contributes to MEK-ERK pathway-dependent PD-L1 upregulation by KRAS mutation in premalignant human bronchial epithelial cells. Am J Transl Res. 2020; 12(2):409-427.
Lee MH, Yanagawa J, Tran L, Walser TC, Bisht B, Fung E, Park SJ, Zeng G, Krysan K, Wallace WD, Paul MK, Girard L, Gao B, Minna JD, Dubinett SM, Lee JM. PMID: 32194893; PMCID: PMC7061839.
View in:
PubMed Mentions:
11
-
The Role of Interleukin 1β in the Pathogenesis of Lung Cancer. JTO Clin Res Rep. 2020 Mar; 1(1):100001.
Garon EB, Chih-Hsin Yang J, Dubinett SM. PMID: 34589908; PMCID: PMC8474414.
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PubMed Mentions:
29
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Factors Associated with Differential Readmission Diagnoses Following Acute Exacerbations of Chronic Obstructive Pulmonary Disease. J Hosp Med. 2020 04 01; 15(4):219-227.
Buhr RG, Jackson NJ, Dubinett SM, Kominski GF, Mangione CM, Ong MK. PMID: 32118572; PMCID: PMC7153488.
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PubMed Mentions:
11 Fields:
Translation:
Humans
-
Chronic IL-1β-induced inflammation regulates epithelial-to-mesenchymal transition memory phenotypes via epigenetic modifications in non-small cell lung cancer. Sci Rep. 2020 01 15; 10(1):377.
Li R, Ong SL, Tran LM, Jing Z, Liu B, Park SJ, Huang ZL, Walser TC, Heinrich EL, Lee G, Salehi-Rad R, Crosson WP, Pagano PC, Paul MK, Xu S, Herschman H, Krysan K, Dubinett S. PMID: 31941995; PMCID: PMC6962381.
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PubMed Mentions:
43 Fields:
Translation:
HumansCells
-
Publisher Correction: In vivo imaging of mitochondrial membrane potential in non-small-cell lung cancer. Nature. 2020 01; 577(7791):E7.
Momcilovic M, Jones A, Bailey ST, Waldmann CM, Li R, Lee JT, Abdelhady G, Gomez A, Holloway T, Schmid E, Stout D, Fishbein MC, Stiles L, Dabir DV, Dubinett SM, Christofk H, Shirihai O, Koehler CM, Sadeghi S, Shackelford DB. PMID: 31896820.
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PubMed Mentions: Fields:
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CCL21 Programs Immune Activity in Tumor Microenvironment. Adv Exp Med Biol. 2020; 1231:67-78.
Sharma S, Kadam P, Dubinett S. PMID: 32060847.
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PubMed Mentions:
11 Fields:
Translation:
HumansAnimalsCells
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Myeloid-derived suppressor cell-dependent inhibition of B cell responses in non-small cell lung cancer. Transl Lung Cancer Res. 2019 Dec; 8(Suppl 4):S331-S333.
Li R, Dubinett SM. PMID: 32038908; PMCID: PMC6987369.
View in:
PubMed Mentions:
2
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In vivo imaging of mitochondrial membrane potential in non-small-cell lung cancer. Nature. 2019 11; 575(7782):380-384.
Momcilovic M, Jones A, Bailey ST, Waldmann CM, Li R, Lee JT, Abdelhady G, Gomez A, Holloway T, Schmid E, Stout D, Fishbein MC, Stiles L, Dabir DV, Dubinett SM, Christofk H, Shirihai O, Koehler CM, Sadeghi S, Shackelford DB. PMID: 31666695; PMCID: PMC7328016.
View in:
PubMed Mentions:
91 Fields:
Translation:
HumansAnimalsCells
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Comorbidity and thirty-day hospital readmission odds in chronic obstructive pulmonary disease: a comparison of the Charlson and Elixhauser comorbidity indices. BMC Health Serv Res. 2019 Oct 15; 19(1):701.
Buhr RG, Jackson NJ, Kominski GF, Dubinett SM, Ong MK, Mangione CM. PMID: 31615508; PMCID: PMC6794890.
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PubMed Mentions:
18 Fields:
Translation:
Humans
-
Driver Mutations in Normal Airway Epithelium Elucidate Spatiotemporal Resolution of Lung Cancer. Am J Respir Crit Care Med. 2019 09 15; 200(6):742-750.
Kadara H, Sivakumar S, Jakubek Y, San Lucas FA, Lang W, McDowell T, Weber Z, Behrens C, Davies GE, Kalhor N, Moran C, El-Zein R, Mehran R, Swisher SG, Wang J, Zhang J, Fujimoto J, Fowler J, Heymach JV, Dubinett S, Spira AE, Ehli EA, Wistuba II, Scheet P. PMID: 30896962; PMCID: PMC6775870.
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PubMed Mentions:
15 Fields:
Translation:
Humans
-
Gene Expression Alterations in the Bronchial Epithelium of e-Cigarette Users. Chest. 2019 10; 156(4):764-773.
Corbett SE, Nitzberg M, Moses E, Kleerup E, Wang T, Perdomo C, Perdomo C, Liu G, Xiao X, Liu H, Elashoff DA, Brooks DR, O'Connor GT, Dubinett SM, Spira A, Lenburg ME. PMID: 31233743; PMCID: PMC6859252.
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PubMed Mentions:
9 Fields:
Translation:
HumansCells
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The Immune Contexture Associates with the Genomic Landscape in Lung Adenomatous Premalignancy. Cancer Res. 2019 Oct 01; 79(19):5022-5033.
Krysan K, Tran LM, Grimes BS, Fishbein GA, Seki A, Gardner BK, Walser TC, Salehi-Rad R, Yanagawa J, Lee JM, Sharma S, Aberle DR, Spira AE, Elashoff DA, Wallace WD, Fishbein MC, Dubinett SM. PMID: 31142513; PMCID: PMC6774823.
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PubMed Mentions:
31 Fields:
Translation:
Humans
-
Tumor Characteristics Associated with Benefit from Pembrolizumab in Advanced Non-Small Cell Lung Cancer. Clin Cancer Res. 2019 08 15; 25(16):5061-5068.
Hu-Lieskovan S, Lisberg A, Zaretsky JM, Grogan TR, Rizvi H, Wells DK, Carroll J, Cummings A, Madrigal J, Jones B, Gukasyan J, Shintaku IP, Slamon D, Dubinett S, Goldman JW, Elashoff D, Hellmann MD, Ribas A, Garon EB. PMID: 31113840; PMCID: PMC6901027.
View in:
PubMed Mentions:
40 Fields:
Translation:
Humans
-
Molecular subtyping reveals immune alterations associated with progression of bronchial premalignant lesions. Nat Commun. 2019 04 23; 10(1):1856.
Beane JE, Mazzilli SA, Campbell JD, Duclos G, Krysan K, Moy C, Perdomo C, Schaffer M, Liu G, Zhang S, Liu H, Vick J, Dhillon SS, Platero SJ, Dubinett SM, Stevenson C, Reid ME, Lenburg ME, Spira AE. PMID: 31015447; PMCID: PMC6478943.
View in:
PubMed Mentions:
51 Fields:
Translation:
HumansCellsPHPublic Health
-
Understanding the mechanisms of immune-evasion by lung cancer in the context of chronic inflammation in emphysema. J Thorac Dis. 2019 Feb; 11(2):382-385.
Salehi-Rad R, Dubinett SM. PMID: 30962980; PMCID: PMC6409254.
View in:
PubMed Mentions:
3
-
Sodium-glucose transporter 2 is a diagnostic and therapeutic target for early-stage lung adenocarcinoma. Sci Transl Med. 2018 11 14; 10(467).
Scafoglio CR, Villegas B, Abdelhady G, Bailey ST, Liu J, Shirali AS, Wallace WD, Magyar CE, Grogan TR, Elashoff D, Walser T, Yanagawa J, Aberle DR, Barrio JR, Dubinett SM, Shackelford DB. PMID: 30429355; PMCID: PMC6428683.
View in:
PubMed Mentions:
71 Fields:
Translation:
HumansAnimals
-
Understanding the Hurdles in Lung Cancer Immunotherapy in the Context of Chronic Obstructive Pulmonary Disease. Am J Respir Crit Care Med. 2018 10 01; 198(7):835-837.
Salehi-Rad R, Dubinett SM. PMID: 29589957.
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PubMed Mentions: Fields:
Translation:
HumansCells
-
Functional profiling of circulating tumor cells with an integrated vortex capture and single-cell protease activity assay. Proc Natl Acad Sci U S A. 2018 10 02; 115(40):9986-9991.
Dhar M, Lam JN, Walser T, Dubinett SM, Rettig MB, Di Carlo D. PMID: 30224472; PMCID: PMC6176626.
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PubMed Mentions:
42 Fields:
Translation:
HumansCells
-
The Society for Immunotherapy of Cancer consensus statement on immunotherapy for the treatment of non-small cell lung cancer (NSCLC). J Immunother Cancer. 2018 07 17; 6(1):75.
Brahmer JR, Govindan R, Anders RA, Antonia SJ, Sagorsky S, Davies MJ, Dubinett SM, Ferris A, Gandhi L, Garon EB, Hellmann MD, Hirsch FR, Malik S, Neal JW, Papadimitrakopoulou VA, Rimm DL, Schwartz LH, Sepesi B, Yeap BY, Rizvi NA, Herbst RS. PMID: 30012210; PMCID: PMC6048854.
View in:
PubMed Mentions:
135 Fields:
Translation:
Humans
-
Randomized phase II study of fulvestrant and erlotinib compared with erlotinib alone in patients with advanced or metastatic non-small cell lung cancer. Lung Cancer. 2018 09; 123:91-98.
Garon EB, Siegfried JM, Stabile LP, Young PA, Marquez-Garban DC, Park DJ, Patel R, Hu EH, Sadeghi S, Parikh RJ, Reckamp KL, Adams B, Elashoff RM, Elashoff D, Grogan T, Wang HJ, Dacic S, Brennan M, Valdes Y, Davenport S, Dubinett SM, Press MF, Slamon DJ, Pietras RJ. PMID: 30089602; PMCID: PMC6118115.
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PubMed Mentions:
25 Fields:
Translation:
HumansCTClinical Trials
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Treating the Intestine with Oral ApoA-I Mimetic Tg6F Reduces Tumor Burden in Mouse Models of Metastatic Lung Cancer. Sci Rep. 2018 06 13; 8(1):9032.
Chattopadhyay A, Yang X, Mukherjee P, Sulaiman D, Fogelman HR, Grijalva V, Dubinett S, Wasler TC, Paul MK, Salehi-Rad R, Mack JJ, Iruela-Arispe ML, Navab M, Fogelman AM, Reddy ST. PMID: 29899427; PMCID: PMC5998131.
View in:
PubMed Mentions:
20 Fields:
Translation:
AnimalsCells
-
The GSK3 Signaling Axis Regulates Adaptive Glutamine Metabolism in Lung Squamous Cell Carcinoma. Cancer Cell. 2018 05 14; 33(5):905-921.e5.
Momcilovic M, Bailey ST, Lee JT, Fishbein MC, Braas D, Go J, Graeber TG, Parlati F, Demo S, Li R, Walser TC, Gricowski M, Shuman R, Ibarra J, Fridman D, Phelps ME, Badran K, St John M, Bernthal NM, Federman N, Yanagawa J, Dubinett SM, Sadeghi S, Christofk HR, Shackelford DB. PMID: 29763624; PMCID: PMC6451645.
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PubMed Mentions:
89 Fields:
Translation:
HumansAnimalsCells
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Summarizing performance for genome scale measurement of miRNA: reference samples and metrics. BMC Genomics. 2018 03 06; 19(1):180.
Pine PS, Lund SP, Parsons JR, Vang LK, Mahabal AA, Cinquini L, Kelly SC, Kincaid H, Crichton DJ, Spira A, Liu G, Gower AC, Pass HI, Goparaju C, Dubinett SM, Krysan K, Stass SA, Kukuruga D, Van Keuren-Jensen K, Courtright-Lim A, Thompson KL, Rosenzweig BA, Sorbara L, Srivastava S, Salit ML. PMID: 29510677; PMCID: PMC5838960.
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PubMed Mentions:
3 Fields:
Translation:
Humans
-
Silencing the Snail-Dependent RNA Splice Regulator ESRP1 Drives Malignant Transformation of Human Pulmonary Epithelial Cells. Cancer Res. 2018 04 15; 78(8):1986-1999.
Walser TC, Jing Z, Tran LM, Lin YQ, Yakobian N, Wang G, Krysan K, Zhu LX, Sharma S, Lee MH, Belperio JA, Ooi AT, Gomperts BN, Shay JW, Larsen JE, Minna JD, Hong LS, Fishbein MC, Dubinett SM. PMID: 29431637; PMCID: PMC5899686.
View in:
PubMed Mentions:
8 Fields:
Translation:
HumansAnimalsCells
-
Impact of Chronic Obstructive Pulmonary Disease on Immune-based Treatment for Lung Cancer. Moving toward Disease Interception. Am J Respir Crit Care Med. 2018 02 01; 197(3):278-280.
Dubinett SM, Spira AE. PMID: 29072842.
View in:
PubMed Mentions:
4 Fields:
Translation:
Humans
-
Serum Monitoring and Phenotype Identification of Stage I Non-Small Cell Lung Cancer Patients. Cancer Invest. 2017 Oct 21; 35(9):573-585.
Hocker JR, Deb SJ, Li M, Lerner MR, Lightfoot SA, Quillet AA, Hanas RJ, Reinersman M, Thompson JL, Vu NT, Kupiec TC, Brackett DJ, Peyton MD, Dubinett SM, Burkhart HM, Postier RG, Hanas JS. PMID: 28949774.
View in:
PubMed Mentions:
11 Fields:
Translation:
HumansCells
-
Genomic Landscape of Atypical Adenomatous Hyperplasia Reveals Divergent Modes to Lung Adenocarcinoma. Cancer Res. 2017 11 15; 77(22):6119-6130.
Sivakumar S, Lucas FAS, McDowell TL, Lang W, Xu L, Fujimoto J, Zhang J, Futreal PA, Fukuoka J, Yatabe Y, Dubinett SM, Spira AE, Fowler J, Hawk ET, Wistuba II, Scheet P, Kadara H. PMID: 28951454; PMCID: PMC5774855.
View in:
PubMed Mentions:
61 Fields:
Translation:
Humans
-
Use of a Novel Polymer in an Animal Model of Head and Neck Squamous Cell Carcinoma. Otolaryngol Head Neck Surg. 2018 01; 158(1):110-117.
Pellionisz PA, Lin Y, Mallen-St Clair J, Luo J, Suwarnasarn A, Schaue D, Elashoff DA, Palma-Diaz F, Dubinett SM, Sharma S, Wu B, St John MA. PMID: 28895464.
View in:
PubMed Mentions:
5 Fields:
Translation:
Animals
-
Alterations in Bronchial Airway miRNA Expression for Lung Cancer Detection. Cancer Prev Res (Phila). 2017 Nov; 10(11):651-659.
Pavel AB, Campbell JD, Liu G, Elashoff D, Dubinett S, Smith K, Whitney D, Lenburg ME, Spira A, AEGIS Study Team. PMID: 28877936; PMCID: PMC6758560.
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PubMed Mentions:
23 Fields:
Translation:
HumansCellsCTClinical Trials
-
Identification of a Human Airway Epithelial Cell Subpopulation with Altered Biophysical, Molecular, and Metastatic Properties. Cancer Prev Res (Phila). 2017 Sep; 10(9):514-524.
Pagano PC, Tran LM, Bendris N, O'Byrne S, Tse HT, Sharma S, Hoech JW, Park SJ, Liclican EL, Jing Z, Li R, Krysan K, Paul MK, Fontebasso Y, Larsen JE, Hakimi S, Seki A, Fishbein MC, Gimzewski JK, Carlo DD, Minna JD, Walser TC, Dubinett SM. PMID: 28754664; PMCID: PMC5584580.
View in:
PubMed Mentions:
6 Fields:
Translation:
HumansAnimalsCells
-
Phase I Trial of Intratumoral Injection of CCL21 Gene-Modified Dendritic Cells in Lung Cancer Elicits Tumor-Specific Immune Responses and CD8+ T-cell Infiltration. Clin Cancer Res. 2017 Aug 15; 23(16):4556-4568.
Lee JM, Lee MH, Garon E, Goldman JW, Salehi-Rad R, Baratelli FE, Schaue D, Wang G, Rosen F, Yanagawa J, Walser TC, Lin Y, Park SJ, Adams S, Marincola FM, Tumeh PC, Abtin F, Suh R, Reckamp KL, Lee G, Wallace WD, Lee S, Zeng G, Elashoff DA, Sharma S, Dubinett SM. PMID: 28468947; PMCID: PMC5599263.
View in:
PubMed Mentions:
110 Fields:
Translation:
HumansCellsCTClinical Trials
-
CancerLocator: non-invasive cancer diagnosis and tissue-of-origin prediction using methylation profiles of cell-free DNA. Genome Biol. 2017 03 24; 18(1):53.
Kang S, Li Q, Chen Q, Zhou Y, Park S, Lee G, Grimes B, Krysan K, Yu M, Wang W, Alber F, Sun F, Dubinett SM, Li W, Zhou XJ. PMID: 28335812; PMCID: PMC5364586.
View in:
PubMed Mentions:
113 Fields:
Translation:
HumansCells
-
Targeted Inhibition of EGFR and Glutaminase Induces Metabolic Crisis in EGFR Mutant Lung Cancer. Cell Rep. 2017 01 17; 18(3):601-610.
Momcilovic M, Bailey ST, Lee JT, Fishbein MC, Magyar C, Braas D, Graeber T, Jackson NJ, Czernin J, Emberley E, Gross M, Janes J, Mackinnon A, Pan A, Rodriguez M, Works M, Zhang W, Parlati F, Demo S, Garon E, Krysan K, Walser TC, Dubinett SM, Sadeghi S, Christofk HR, Shackelford DB. PMID: 28099841; PMCID: PMC5260616.
View in:
PubMed Mentions:
79 Fields:
Translation:
HumansAnimalsCells
-
Assessing Researcher Needs for a Virtual Biobank. Biopreserv Biobank. 2017 Jun; 15(3):203-210.
van Draanen J, Davidson P, Bour-Jordan H, Bowman-Carpio L, Boyle D, Dubinett S, Gardner B, Gardner J, McFall C, Mercola D, Nakazono T, Soares S, Stoppler H, Tempero M, Vandenberg S, Wan YJ, Dry S. PMID: 27929677; PMCID: PMC5749588.
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PubMed Mentions:
8 Fields:
Translation:
Humans
-
Lung Cancer: Evolving Concepts in Management. Semin Respir Crit Care Med. 2016 10; 37(5):647-648.
Arenberg D, Dubinett SM. PMID: 27732986.
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PubMed Mentions: Fields:
Translation:
Humans
-
Molecular Impact of Electronic Cigarette Aerosol Exposure in Human Bronchial Epithelium. Toxicol Sci. 2017 01; 155(1):248-257.
Moses E, Wang T, Corbett S, Jackson GR, Drizik E, Perdomo C, Perdomo C, Kleerup E, Brooks D, O'Connor G, Dubinett S, Hayden P, Lenburg ME, Spira A. PMID: 27701119; PMCID: PMC5216655.
View in:
PubMed Mentions:
35 Fields:
Translation:
Humans
-
p38 MAPK mediates epithelial-mesenchymal transition by regulating p38IP and Snail in head and neck squamous cell carcinoma. Oral Oncol. 2016 09; 60:81-9.
Lin Y, Mallen-St Clair J, Wang G, Luo J, Palma-Diaz F, Lai C, Elashoff DA, Sharma S, Dubinett SM, St John M. PMID: 27531877.
View in:
PubMed Mentions:
18 Fields:
Translation:
HumansCells
-
MCT1 Modulates Cancer Cell Pyruvate Export and Growth of Tumors that Co-express MCT1 and MCT4. Cell Rep. 2016 Feb 23; 14(7):1590-1601.
Hong CS, Graham NA, Gu W, Espindola Camacho C, Mah V, Maresh EL, Alavi M, Bagryanova L, Krotee PAL, Gardner BK, Behbahan IS, Horvath S, Chia D, Mellinghoff IK, Hurvitz SA, Dubinett SM, Critchlow SE, Kurdistani SK, Goodglick L, Braas D, Graeber TG, Christofk HR. PMID: 26876179; PMCID: PMC4816454.
View in:
PubMed Mentions:
116 Fields:
Translation:
HumansAnimalsCells
-
Heightening Energetic Stress Selectively Targets LKB1-Deficient Non-Small Cell Lung Cancers. Cancer Res. 2015 Nov 15; 75(22):4910-22.
Momcilovic M, McMickle R, Abt E, Seki A, Simko SA, Magyar C, Stout DB, Fishbein MC, Walser TC, Dubinett SM, Shackelford DB. PMID: 26574479; PMCID: PMC4654699.
View in:
PubMed Mentions:
29 Fields:
Translation:
HumansAnimalsCells
-
p53 modulates NF-κB mediated epithelial-to-mesenchymal transition in head and neck squamous cell carcinoma. Oral Oncol. 2015 Oct; 51(10):921-8.
Lin Y, Mallen-St Clair J, Luo J, Sharma S, Dubinett S, St John M. PMID: 26306422.
View in:
PubMed Mentions:
9 Fields:
Translation:
HumansCells
-
Randomized phase 2 trial of erlotinib in combination with high-dose celecoxib or placebo in patients with advanced non-small cell lung cancer. Cancer. 2015 Sep 15; 121(18):3298-306.
Reckamp KL, Koczywas M, Cristea MC, Dowell JE, Wang HJ, Gardner BK, Milne GL, Figlin RA, Fishbein MC, Elashoff RM, Dubinett SM. PMID: 26033830; PMCID: PMC4864011.
View in:
PubMed Mentions:
21 Fields:
Translation:
HumansCTClinical Trials
-
GITR agonist enhances vaccination responses in lung cancer. Oncoimmunology. 2015 Apr; 4(4):e992237.
Zhu LX, Davoodi M, Srivastava MK, Kachroo P, Lee JM, St John M, Harris-White M, Huang M, Strieter RM, Dubinett S, Sharma S. PMID: 26137407; PMCID: PMC4485739.
View in:
PubMed Mentions:
10 Fields:
-
Drug Development for Metastasis Prevention. Crit Rev Oncog. 2015; 20(5-6):449-73.
Fontebasso Y, Dubinett SM. PMID: 27279241; PMCID: PMC6497172.
View in:
PubMed Mentions:
22 Fields:
Translation:
HumansAnimals
-
Combination Treatment with Apricoxib and IL-27 Enhances Inhibition of Epithelial-Mesenchymal Transition in Human Lung Cancer Cells through a STAT1 Dominant Pathway. J Cancer Sci Ther. 2014 Nov; 6(11):468-477.
Lee MH, Kachroo P, Pagano PC, Yanagawa J, Wang G, Walser TC, Krysan K, Sharma S, John MS, Dubinett SM, Lee JM. PMID: 26523208; PMCID: PMC4624255.
View in:
PubMed Mentions:
7
-
Loss of miR125a expression in a model of K-ras-dependent pulmonary premalignancy. Cancer Prev Res (Phila). 2014 Aug; 7(8):845-55.
Liclican EL, Walser TC, Hazra S, Krysan K, Park SJ, Pagano PC, Gardner BK, Larsen JE, Minna JD, Dubinett SM. PMID: 24913817; PMCID: PMC4125465.
View in:
PubMed Mentions:
2 Fields:
Translation:
HumansCells
-
A cytokine-delivering polymer is effective in reducing tumor burden in a head and neck squamous cell carcinoma murine model. Otolaryngol Head Neck Surg. 2014 Sep; 151(3):447-53.
Lin Y, Luo J, Zhu WE, Srivastava M, Schaue D, Elashoff DA, Dubinett SM, Sharma S, Wu B, St John MA. PMID: 24825873; PMCID: PMC4167678.
View in:
PubMed Mentions:
2 Fields:
Translation:
Animals
-
Molecular profiling of premalignant lesions in lung squamous cell carcinomas identifies mechanisms involved in stepwise carcinogenesis. Cancer Prev Res (Phila). 2014 May; 7(5):487-95.
Ooi AT, Gower AC, Zhang KX, Vick JL, Hong L, Nagao B, Wallace WD, Elashoff DA, Walser TC, Dubinett SM, Pellegrini M, Lenburg ME, Spira A, Gomperts BN. PMID: 24618292; PMCID: PMC4059064.
View in:
PubMed Mentions:
51 Fields:
Translation:
Humans
-
Distinguishing patients with stage I lung cancer versus control individuals using serum mass profiling. Cancer Invest. 2014 May; 32(4):136-43.
Hanas JS, Peyton MD, Lerner MR, Lightfoot SA, Deb SJ, Hanas RJ, Vu NT, Kupiec TC, Stowell DE, Brackett DJ, Dubinett SM, Hocker JR. PMID: 24579933.
View in:
PubMed Mentions:
2 Fields:
Translation:
Humans
-
PGE2-driven expression of c-Myc and oncomiR-17-92 contributes to apoptosis resistance in NSCLC. Mol Cancer Res. 2014 May; 12(5):765-74.
Krysan K, Kusko R, Grogan T, O'Hearn J, Reckamp KL, Walser TC, Garon EB, Lenburg ME, Sharma S, Spira AE, Elashoff D, Dubinett SM. PMID: 24469837; PMCID: PMC4020971.
View in:
PubMed Mentions:
14 Fields:
Translation:
HumansCells
-
Dichloroacetate should be considered with platinum-based chemotherapy in hypoxic tumors rather than as a single agent in advanced non-small cell lung cancer. J Cancer Res Clin Oncol. 2014 Mar; 140(3):443-52.
Garon EB, Christofk HR, Hosmer W, Britten CD, Bahng A, Crabtree MJ, Hong CS, Kamranpour N, Pitts S, Kabbinavar F, Patel C, von Euw E, Black A, Michelakis ED, Dubinett SM, Slamon DJ. PMID: 24442098; PMCID: PMC3939783.
View in:
PubMed Mentions:
64 Fields:
Translation:
HumansCellsCTClinical Trials
-
IL-27 inhibits epithelial-mesenchymal transition and angiogenic factor production in a STAT1-dominant pathway in human non-small cell lung cancer. J Exp Clin Cancer Res. 2013 Nov 25; 32:97.
Kachroo P, Lee MH, Zhang L, Baratelli F, Lee G, Srivastava MK, Wang G, Walser TC, Krysan K, Sharma S, Dubinett SM, Lee JM. PMID: 24274066; PMCID: PMC3906956.
View in:
PubMed Mentions:
46 Fields:
Translation:
HumansCells
-
A novel molecular pathway for Snail-dependent, SPARC-mediated invasion in non-small cell lung cancer pathogenesis. Cancer Prev Res (Phila). 2014 Jan; 7(1):150-60.
Grant JL, Fishbein MC, Hong LS, Krysan K, Minna JD, Shay JW, Walser TC, Dubinett SM. PMID: 24253315; PMCID: PMC3919444.
View in:
PubMed Mentions:
19 Fields:
Translation:
HumansCells
-
MicroRNA 4423 is a primate-specific regulator of airway epithelial cell differentiation and lung carcinogenesis. Proc Natl Acad Sci U S A. 2013 Nov 19; 110(47):18946-51.
Perdomo C, Campbell JD, Gerrein J, Tellez CS, Garrison CB, Walser TC, Drizik E, Si H, Gower AC, Vick J, Anderlind C, Jackson GR, Mankus C, Schembri F, O'Hara C, Gomperts BN, Dubinett SM, Hayden P, Belinsky SA, Lenburg ME, Spira A. PMID: 24158479; PMCID: PMC3839685.
View in:
PubMed Mentions:
34 Fields:
Translation:
HumansAnimals
-
Models of interinstitutional partnerships between research intensive universities and minority serving institutions (MSI) across the Clinical Translational Science Award (CTSA) consortium. Clin Transl Sci. 2013 Dec; 6(6):435-43.
Ofili EO, Fair A, Norris K, Verbalis JG, Poland R, Bernard G, Stephens DS, Dubinett SM, Imperato-McGinley J, Dottin RP, Pulley J, West A, Brown A, Mellman TA. PMID: 24119157; PMCID: PMC4038384.
View in:
PubMed Mentions:
20 Fields:
Translation:
Humans
-
Challenge and opportunity of targeted lung cancer chemoprevention. J Clin Oncol. 2013 Nov 20; 31(33):4169-71.
Dubinett SM, Spira A. PMID: 24002497.
View in:
PubMed Mentions:
4 Fields:
Translation:
Humans
-
Elevated neutrophil gelatinase-associated lipocalin contributes to erlotinib resistance in non-small cell lung cancer. Am J Transl Res. 2013; 5(5):481-96.
Krysan K, Cui X, Gardner BK, Reckamp KL, Wang X, Hong L, Walser TC, Rodriguez NL, Pagano PC, Garon EB, Brothers JF, Elashoff D, Lee JM, Spira AE, Sharma S, Fishbein MC, Dubinett SM. PMID: 23977408; PMCID: PMC3745436.
View in:
PubMed Mentions:
13
-
Effect of epigenetic histone modifications on E-cadherin splicing and expression in lung cancer. Am J Cancer Res. 2013; 3(4):374-89.
Liao W, Jordaan G, Srivastava MK, Dubinett S, Sharma S, Sharma S. PMID: 23977447; PMCID: PMC3744017.
View in:
PubMed Mentions:
15
-
Characteristics of lung cancers harboring NRAS mutations. Clin Cancer Res. 2013 May 01; 19(9):2584-91.
Ohashi K, Sequist LV, Arcila ME, Lovly CM, Chen X, Rudin CM, Moran T, Camidge DR, Vnencak-Jones CL, Berry L, Pan Y, Sasaki H, Engelman JA, Garon EB, Dubinett SM, Franklin WA, Riely GJ, Sos ML, Kris MG, Dias-Santagata D, Ladanyi M, Bunn PA, Pao W. PMID: 23515407; PMCID: PMC3643999.
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PubMed Mentions:
66 Fields:
Translation:
HumansCells
-
TLR3 agonists and proinflammatory antitumor activities. Expert Opin Ther Targets. 2013 May; 17(5):481-3.
Sharma S, Zhu L, Davoodi M, Harris-White M, Lee JM, St John M, Salgia R, Dubinett S. PMID: 23506058; PMCID: PMC3758767.
View in:
PubMed Mentions:
12 Fields:
Translation:
HumansAnimals
-
The HSP90 inhibitor NVP-AUY922 potently inhibits non-small cell lung cancer growth. Mol Cancer Ther. 2013 Jun; 12(6):890-900.
Garon EB, Finn RS, Hamidi H, Dering J, Pitts S, Kamranpour N, Desai AJ, Hosmer W, Ide S, Avsar E, Jensen MR, Quadt C, Liu M, Dubinett SM, Slamon DJ. PMID: 23493311; PMCID: PMC3681857.
View in:
PubMed Mentions:
36 Fields:
Translation:
HumansCells
-
Antiestrogen fulvestrant enhances the antiproliferative effects of epidermal growth factor receptor inhibitors in human non-small-cell lung cancer. J Thorac Oncol. 2013 Mar; 8(3):270-8.
Garon EB, Pietras RJ, Finn RS, Kamranpour N, Pitts S, Márquez-Garbán DC, Desai AJ, Dering J, Hosmer W, von Euw EM, Dubinett SM, Slamon DJ. PMID: 23399957; PMCID: PMC3573351.
View in:
PubMed Mentions:
30 Fields:
Translation:
HumansCells
-
CCL21 Chemokine Therapy for Lung Cancer. Int Trends Immun. 2013 Jan; 1(1):10-15.
Sharma S, Zhu L, Srivastava MK, Harris-White M, Huang M, Lee JM, Rosen F, Lee G, Wang G, Kickhoefer V, Rome LH, Baratelli F, St John M, Reckamp K, Chul-Yang S, Hillinger S, Strieter R, Dubinett S. PMID: 25264541; PMCID: PMC4175527.
View in:
PubMed Mentions:
9
-
Enriching the molecular definition of the airway "field of cancerization:" establishing new paradigms for the patient at risk for lung cancer. Cancer Prev Res (Phila). 2013 Jan; 6(1):4-7.
Gomperts BN, Walser TC, Spira A, Dubinett SM. PMID: 23233734; PMCID: PMC3717378.
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PubMed Mentions:
16 Fields:
Translation:
Humans
-
Targeting MDSCs enhance therapeutic vaccination responses against lung cancer. Oncoimmunology. 2012 Dec 01; 1(9):1650-1651.
Srivastava MK, Dubinett S, Sharma S. PMID: 23264925; PMCID: PMC3525634.
View in:
PubMed Mentions:
14 Fields:
-
CD14(+)S100A9(+) myeloid-derived suppressor cells portend decreased survival in patients with advanced lung cancer. Am J Respir Crit Care Med. 2012 Nov 15; 186(10):940-1.
Sharma S, Dubinett S, Salgia R. PMID: 23155211; PMCID: PMC4249776.
View in:
PubMed Mentions:
2 Fields:
Translation:
HumansCells
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Green tea inhibits cycolooxygenase-2 in non-small cell lung cancer cells through the induction of Annexin-1. Biochem Biophys Res Commun. 2012 Nov 02; 427(4):725-30.
Lu QY, Jin Y, Mao JT, Zhang ZF, Heber D, Dubinett SM, Rao J. PMID: 23036202; PMCID: PMC3490045.
View in:
PubMed Mentions:
8 Fields:
Translation:
HumansAnimalsCells
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Targeting myeloid-derived suppressor cells augments antitumor activity against lung cancer. Immunotargets Ther. 2012 Oct 01; 2012(1):7-12.
Srivastava MK, Zhu L, Harris-White M, Huang M, St John M, Lee JM, Salgia R, Cameron RB, Strieter R, Dubinett S, Sharma S. PMID: 24791250; PMCID: PMC4004632.
View in:
PubMed Mentions:
15
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Apricoxib upregulates 15-PGDH and PGT in tobacco-related epithelial malignancies. Br J Cancer. 2012 Aug 07; 107(4):707-12.
St John MA, Wang G, Luo J, Dohadwala M, Hu D, Lin Y, Dennis M, Lee JM, Elashoff D, Lawhon T, Zaknoen SL, Burrows FJ, Dubinett SM. PMID: 22828609; PMCID: PMC3419945.
View in:
PubMed Mentions:
4 Fields:
Translation:
HumansCells
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Myeloid suppressor cell depletion augments antitumor activity in lung cancer. PLoS One. 2012; 7(7):e40677.
Srivastava MK, Zhu L, Harris-White M, Kar UK, Kar U, Huang M, Johnson MF, Lee JM, Elashoff D, Strieter R, Dubinett S, Sharma S. PMID: 22815789; PMCID: PMC3398024.
View in:
PubMed Mentions:
123 Fields:
Translation:
AnimalsCellsPHPublic Health
-
Snail controls the mesenchymal phenotype and drives erlotinib resistance in oral epithelial and head and neck squamous cell carcinoma cells. Otolaryngol Head Neck Surg. 2012 Oct; 147(4):726-32.
Dennis M, Wang G, Luo J, Lin Y, Dohadwala M, Abemayor E, Elashoff DA, Sharma S, Dubinett SM, St John MA. PMID: 22568942; PMCID: PMC4167686.
View in:
PubMed Mentions:
15 Fields:
Translation:
HumansCells
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A novel modular polymer platform for the treatment of head and neck squamous cell carcinoma in an animal model. Arch Otolaryngol Head Neck Surg. 2012 Apr; 138(4):412-7.
Hu D, Lau OD, Wang L, Wang G, Schaue D, Zhu L, Huang M, Lin Y, Dennis M, Abemayor E, Elashoff DA, Dubinett SM, McBride WH, Sharma S, Wu B, St John MA. PMID: 22508626; PMCID: PMC4167672.
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PubMed Mentions:
6 Fields:
Translation:
Animals
-
Preparedness of the CTSA's structural and scientific assets to support the mission of the National Center for Advancing Translational Sciences (NCATS). Clin Transl Sci. 2012 Apr; 5(2):121-9.
CTSA Principal Investigators, Shamoon H, Center D, Davis P, Tuchman M, Ginsberg H, Califf R, Stephens D, Mellman T, Verbalis J, Nadler L, Shekhar A, Ford D, Rizza R, Shaker R, Brady K, Murphy B, Cronstein B, Hochman J, Greenland P, Orwoll E, Sinoway L, Greenberg H, Jackson R, Coller B, Topol E, Guay-Woodford L, Runge M, Clark R, McClain D, Selker H, Lowery C, Dubinett S, Berglund L, Cooper D, Firestein G, Johnston SC, Solway J, Heubi J, Sokol R, Nelson D, Tobacman L, Rosenthal G, Aaronson L, Barohn R, Kern P, Sullivan J, Shanley T, Blazar B, Larson R, FitzGerald G, Reis S, Pearson T, Buchanan T, McPherson D, Brasier A, Toto R, Disis M, Drezner M, Bernard G, Clore J, Evanoff B, Imperato-McGinley J, Sherwin R, Pulley J. PMID: 22507116; PMCID: PMC3335735.
View in:
PubMed Mentions:
13 Fields:
Translation:
HumansAnimals
-
Myeloid suppressor cells and immune modulation in lung cancer. Immunotherapy. 2012 Mar; 4(3):291-304.
Srivastava MK, Andersson Å, Zhu L, Harris-White M, Lee JM, Dubinett S, Sharma S. PMID: 22401635; PMCID: PMC3324285.
View in:
PubMed Mentions:
46 Fields:
Translation:
HumansAnimalsCells
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Na,K-ATPase is a target of cigarette smoke and reduced expression predicts poor patient outcome of smokers with lung cancer. Am J Physiol Lung Cell Mol Physiol. 2012 Jun 01; 302(11):L1150-8.
Huynh TP, Mah V, Sampson VB, Chia D, Fishbein MC, Horvath S, Alavi M, Wu DC, Harper J, Sarafian T, Dubinett SM, Langhans SA, Goodglick L, Rajasekaran AK. PMID: 22345575; PMCID: PMC3379038.
View in:
PubMed Mentions:
5 Fields:
Translation:
HumansAnimalsCells
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Mitotic inhibitors. J Thorac Oncol. 2011 Nov; 6(11 Suppl 4):S1791-2.
Garon EB, Dubinett SM. PMID: 22005532; PMCID: PMC3812544.
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PubMed Mentions: Fields:
Translation:
Humans
-
The inflammatory tumor microenvironment, epithelial mesenchymal transition and lung carcinogenesis. Cancer Microenviron. 2012 Apr; 5(1):5-18.
Heinrich EL, Walser TC, Krysan K, Liclican EL, Grant JL, Rodriguez NL, Dubinett SM. PMID: 21922183; PMCID: PMC3343201.
View in:
PubMed Mentions:
37
-
MUC1 peptide vaccine mediated antitumor activity in non-small cell lung cancer. Expert Opin Biol Ther. 2011 Aug; 11(8):987-90.
Sharma S, Srivastava MK, Harris-White M, Lee JM, Dubinett S. PMID: 21711210; PMCID: PMC3132083.
View in:
PubMed Mentions:
8 Fields:
Translation:
Humans
-
Mast cells and histamine enhance the proliferation of non-small cell lung cancer cells. Lung Cancer. 2012 Jan; 75(1):38-44.
Stoyanov E, Uddin M, Mankuta D, Dubinett SM, Levi-Schaffer F. PMID: 21733595.
View in:
PubMed Mentions:
37 Fields:
Translation:
HumansAnimalsCells
-
Lung cancer chemoprevention with celecoxib in former smokers. Cancer Prev Res (Phila). 2011 Jul; 4(7):984-93.
Mao JT, Roth MD, Fishbein MC, Aberle DR, Zhang ZF, Rao JY, Tashkin DP, Goodglick L, Holmes EC, Cameron RB, Dubinett SM, Elashoff R, Szabo E, Elashoff D. PMID: 21733822; PMCID: PMC3153413.
View in:
PubMed Mentions:
41 Fields:
Translation:
HumansCTClinical Trials
-
Reduced lung-cancer mortality with low-dose computed tomographic screening. N Engl J Med. 2011 Aug 04; 365(5):395-409.
National Lung Screening Trial Research Team, Aberle DR, Adams AM, Berg CD, Black WC, Clapp JD, Fagerstrom RM, Gareen IF, Gatsonis C, Marcus PM, Sicks JD. PMID: 21714641; PMCID: PMC4356534.
View in:
PubMed Mentions:
3991 Fields:
Translation:
Humans
-
Role of CXCR3 ligands in IL-7/IL-7R alpha-Fc-mediated antitumor activity in lung cancer. Clin Cancer Res. 2011 Jun 01; 17(11):3660-72.
Andersson A, Srivastava MK, Harris-White M, Huang M, Zhu L, Elashoff D, Strieter RM, Dubinett SM, Sharma S. PMID: 21636553; PMCID: PMC3118413.
View in:
PubMed Mentions:
28 Fields:
Translation:
AnimalsCells
-
Systematic quantitative characterization of cellular responses induced by multiple signals. BMC Syst Biol. 2011 May 30; 5:88.
Al-Shyoukh I, Yu F, Feng J, Yan K, Dubinett S, Ho CM, Shamma JS, Sun R. PMID: 21624115; PMCID: PMC3138445.
View in:
PubMed Mentions:
32 Fields:
Translation:
HumansCells
-
Novel CCL21-vault nanocapsule intratumoral delivery inhibits lung cancer growth. PLoS One. 2011 May 03; 6(5):e18758.
Kar UK, Srivastava MK, Andersson A, Baratelli F, Huang M, Kickhoefer VA, Dubinett SM, Rome LH, Sharma S. PMID: 21559281; PMCID: PMC3086906.
View in:
PubMed Mentions:
50 Fields:
Translation:
HumansAnimalsCells
-
Evolving concepts in lung carcinogenesis. Semin Respir Crit Care Med. 2011 Feb; 32(1):32-43.
Gomperts BN, Spira A, Massion PP, Walser TC, Wistuba II, Minna JD, Dubinett SM. PMID: 21500122; PMCID: PMC3423907.
View in:
PubMed Mentions:
37 Fields:
Translation:
HumansAnimalsCells
-
Elevated levels of CXC chemokine connective tissue activating peptide (CTAP)-III in lung cancer patients. Am J Transl Res. 2011 May 15; 3(3):226-33.
Lee G, Gardner BK, Elashoff DA, Purcell CM, Sandha HS, Mao JT, Krysan K, Lee JM, Dubinett SM. PMID: 21654877; PMCID: PMC3102566.
View in:
PubMed Mentions:
5
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Snail as a novel marker for regional metastasis in head and neck squamous cell carcinoma. Am J Otolaryngol. 2012 Jan-Feb; 33(1):6-13.
Mendelsohn AH, Lai CK, Shintaku IP, Fishbein MC, Brugman K, Elashoff DA, Abemayor E, Dubinett SM, St John MA. PMID: 21439681; PMCID: PMC5875698.
View in:
PubMed Mentions:
17 Fields:
Translation:
Humans
-
c-Crk proto-oncogene contributes to transcriptional repression of p120-catenin in non-small cell lung cancer cells. Clin Exp Metastasis. 2011 Apr; 28(4):391-404.
Mortazavi F, Dubinett S, Rettig M. PMID: 21336985; PMCID: PMC3081060.
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PubMed Mentions:
9 Fields:
Translation:
HumansCells
-
Novel drugs--miscellaneous category. J Thorac Oncol. 2010 Dec; 5(12 Suppl 6):S468-9.
Hosmer WD, Dubinett SM, Garon EB. PMID: 21102242.
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PubMed Mentions: Fields:
Translation:
Humans
-
Poly(ADP-ribose) polymerase inhibitors. J Thorac Oncol. 2010 Dec; 5(12 Suppl 6):S455-6.
Garon EB, Dubinett SM. PMID: 21102236.
View in:
PubMed Mentions:
1 Fields:
Translation:
Humans
-
National Lung Cancer Screening Trial American College of Radiology Imaging Network Specimen Biorepository originating from the Contemporary Screening for the Detection of Lung Cancer Trial (NLST, ACRIN 6654): design, intent, and availability of specimens for validation of lung cancer biomarkers. J Thorac Oncol. 2010 Oct; 5(10):1502-6.
Patz EF, Caporaso NE, Dubinett SM, Massion PP, Hirsch FR, Minna JD, Gatsonis C, Duan F, Adams A, Apgar C, Medina RM, Aberle DR. PMID: 20871260; PMCID: PMC2963472.
View in:
PubMed Mentions:
16 Fields:
Translation:
Humans
-
Histopathologic findings of HPV and p16 positive HNSCC. Laryngoscope. 2010 Sep; 120(9):1788-94.
Mendelsohn AH, Lai CK, Shintaku IP, Elashoff DA, Dubinett SM, Abemayor E, St John MA. PMID: 20803740.
View in:
PubMed Mentions:
39 Fields:
Translation:
Humans
-
Presence of a putative tumor-initiating progenitor cell population predicts poor prognosis in smokers with non-small cell lung cancer. Cancer Res. 2010 Aug 15; 70(16):6639-48.
Ooi AT, Mah V, Nickerson DW, Gilbert JL, Ha VL, Hegab AE, Horvath S, Alavi M, Maresh EL, Chia D, Gower AC, Lenburg ME, Spira A, Solis LM, Wistuba II, Walser TC, Wallace WD, Dubinett SM, Goodglick L, Gomperts BN. PMID: 20710044; PMCID: PMC2924777.
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PubMed Mentions:
36 Fields:
Translation:
HumansAnimalsCells
-
Chemokines: can effector cells be redirected to the site of the tumor? Cancer J. 2010 Jul-Aug; 16(4):325-35.
Dubinett SM, Lee JM, Sharma S, Mulé JJ. PMID: 20693843; PMCID: PMC3076643.
View in:
PubMed Mentions:
23 Fields:
Translation:
HumansAnimals
-
PGE(2) contributes to TGF-beta induced T regulatory cell function in human non-small cell lung cancer. Am J Transl Res. 2010 Jun 30; 2(4):356-67.
Baratelli F, Lee JM, Hazra S, Lin Y, Walser TC, Schaue D, Pak PS, Elashoff D, Reckamp K, Zhang L, Fishbein MC, Sharma S, Dubinett SM. PMID: 20733946; PMCID: PMC2923860.
View in:
PubMed Mentions:
31
-
p120-catenin is transcriptionally downregulated by FOXC2 in non-small cell lung cancer cells. Mol Cancer Res. 2010 May; 8(5):762-74.
Mortazavi F, An J, Dubinett S, Rettig M. PMID: 20460685.
View in:
PubMed Mentions:
30 Fields:
Translation:
HumansCells
-
The role of ZEB1 in the inflammation-induced promotion of EMT in HNSCC. Otolaryngol Head Neck Surg. 2010 May; 142(5):753-9.
Dohadwala M, Wang G, Heinrich E, Luo J, Lau O, Shih H, Munaim Q, Lee G, Hong L, Lai C, Abemayor E, Fishbein MC, Elashoff DA, Dubinett SM, St John MA. PMID: 20416468.
View in:
PubMed Mentions:
23 Fields:
Translation:
HumansCells
-
Cancer and inflammation: promise for biologic therapy. J Immunother. 2010 May; 33(4):335-51.
Demaria S, Pikarsky E, Karin M, Coussens LM, Chen YC, El-Omar EM, Trinchieri G, Dubinett SM, Mao JT, Szabo E, Krieg A, Weiner GJ, Fox BA, Coukos G, Wang E, Abraham RT, Carbone M, Lotze MT. PMID: 20386472; PMCID: PMC2941912.
View in:
PubMed Mentions:
133 Fields:
Translation:
HumansAnimals
-
Lung cancer biomarkers: FISHing in the sputum for risk assessment and early detection. Cancer Prev Res (Phila). 2010 Apr; 3(4):420-3.
Gomperts BN, Spira A, Elashoff DE, Dubinett SM. PMID: 20332300.
View in:
PubMed Mentions:
3 Fields:
Translation:
Humans
-
Snail promotes CXCR2 ligand-dependent tumor progression in non-small cell lung carcinoma. Clin Cancer Res. 2009 Nov 15; 15(22):6820-9.
Yanagawa J, Walser TC, Zhu LX, Hong L, Fishbein MC, Mah V, Chia D, Goodglick L, Elashoff DA, Luo J, Magyar CE, Dohadwala M, Lee JM, St John MA, Strieter RM, Sharma S, Dubinett SM. PMID: 19887480; PMCID: PMC2783274.
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PubMed Mentions:
68 Fields:
Translation:
HumansAnimalsCells
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Intracellular signaling molecules. J Thorac Oncol. 2009 Nov; 4(11 Suppl 3):S1057-8.
Garon EB, Dubinett SM. PMID: 19861915.
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PubMed Mentions: Fields:
Translation:
HumansCells
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Proinflammatory mediators upregulate snail in head and neck squamous cell carcinoma. Clin Cancer Res. 2009 Oct 01; 15(19):6018-27.
St John MA, Dohadwala M, Luo J, Wang G, Lee G, Shih H, Heinrich E, Krysan K, Walser T, Hazra S, Zhu L, Lai C, Abemayor E, Fishbein M, Elashoff DA, Sharma S, Dubinett SM. PMID: 19789323; PMCID: PMC2782528.
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PubMed Mentions:
44 Fields:
Translation:
HumansAnimalsCells
-
Regression of recurrent respiratory papillomatosis with celecoxib and erlotinib combination therapy. Chest. 2009 Sep; 136(3):924-926.
Limsukon A, Susanto I, Soo Hoo GW, Dubinett SM, Batra RK. PMID: 19736197.
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PubMed Mentions:
14 Fields:
Translation:
Humans
-
Towards effective immunotherapy for lung cancer: simultaneous targeting of tumor-initiating cells and immune pathways in the tumor microenvironment. Immunotherapy. 2009 Sep; 1(5):721-5.
Dubinett S, Sharma S. PMID: 20636013.
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PubMed Mentions:
6 Fields:
Translation:
HumansAnimalsCells
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The launch of the american journal of translational research. Am J Transl Res. 2009 Sep 01; 1(1):i.
Lee WH, Hung MC, Iczkowski KA, Languino LR, Dubinett SM, Wang D. PMID: 19966932; PMCID: PMC2776285.
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PubMed Mentions:
1
-
Chronic inflammation, chronic obstructive pulmonary disease, and lung cancer. Curr Opin Pulm Med. 2009 Jul; 15(4):303-7.
Lee G, Walser TC, Dubinett SM. PMID: 19417670.
View in:
PubMed Mentions:
74 Fields:
Translation:
Humans
-
CXCR4 expression on circulating pan-cytokeratin positive cells is associated with survival in patients with advanced non-small cell lung cancer. BMC Cancer. 2009 Jun 29; 9:213.
Reckamp KL, Figlin RA, Burdick MD, Dubinett SM, Elashoff RM, Strieter RM. PMID: 19563666; PMCID: PMC2708193.
View in:
PubMed Mentions:
21 Fields:
Translation:
HumansCells
-
IL-7 promotes CXCR3 ligand-dependent T cell antitumor reactivity in lung cancer. J Immunol. 2009 Jun 01; 182(11):6951-8.
Andersson A, Yang SC, Huang M, Zhu L, Kar UK, Batra RK, Elashoff D, Strieter RM, Dubinett SM, Sharma S. PMID: 19454692.
View in:
PubMed Mentions:
56 Fields:
Translation:
AnimalsCells
-
Lung cancer and chronic obstructive pulmonary disease: needs and opportunities for integrated research. J Natl Cancer Inst. 2009 Apr 15; 101(8):554-9.
Punturieri A, Szabo E, Croxton TL, Shapiro SD, Dubinett SM. PMID: 19351920; PMCID: PMC2669099.
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PubMed Mentions:
83 Fields:
Translation:
Humans
-
Effects of green tea extract on lung cancer A549 cells: proteomic identification of proteins associated with cell migration. Proteomics. 2009 Feb; 9(3):757-67.
Lu QY, Yang Y, Jin YS, Zhang ZF, Heber D, Li FP, Dubinett SM, Sondej MA, Loo JA, Rao JY. PMID: 19137550; PMCID: PMC2775082.
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PubMed Mentions:
12 Fields:
Translation:
HumansCells
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Smoking and lung cancer: the role of inflammation. Proc Am Thorac Soc. 2008 Dec 01; 5(8):811-5.
Walser T, Cui X, Yanagawa J, Lee JM, Heinrich E, Lee G, Sharma S, Dubinett SM. PMID: 19017734; PMCID: PMC4080902.
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PubMed Mentions:
131 Fields:
Translation:
Humans
-
The partners--airflow obstruction, emphysema, and lung cancer. Am J Respir Crit Care Med. 2008 Oct 01; 178(7):665-6.
Dubinett SM, Aberle DR, Tashkin DP, Mao JT. PMID: 18796652.
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PubMed Mentions:
1 Fields:
Translation:
Humans
-
Focusing downstream in lung cancer prevention: 15-hydroxyprostaglandin dehydrogenase. Cancer Prev Res (Phila). 2008 Sep; 1(4):223-5.
Dubinett SM, Mao JT, Hazra S. PMID: 19138963.
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PubMed Mentions:
4 Fields:
Translation:
HumansCells
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Pre-clinical characterization of GMP grade CCL21-gene modified dendritic cells for application in a phase I trial in non-small cell lung cancer. J Transl Med. 2008 Jul 22; 6:38.
Baratelli F, Takedatsu H, Hazra S, Peebles K, Luo J, Kurimoto PS, Zeng G, Batra RK, Sharma S, Dubinett SM, Lee JM. PMID: 18644162; PMCID: PMC2507704.
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PubMed Mentions:
17 Fields:
Translation:
HumansCells
-
Summary report 7th Annual Targeted Therapies of the Treatment of Lung Cancer. J Thorac Oncol. 2008 May; 3(5):545-55.
Einhorn LH, Bonomi P, Bunn PA, Camidge DR, Carbone DP, Choy H, Dubinett SM, Gandara DR, Gaspar LE, Govindan R, Johnson DH, Minna JD, Scagliotti G, West HJ, Herbst RS. PMID: 18449013; PMCID: PMC3374724.
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PubMed Mentions:
2 Fields:
Translation:
HumansCells
-
Inflammation in lung carcinogenesis: new targets for lung cancer chemoprevention and treatment. Crit Rev Oncol Hematol. 2008 Jun; 66(3):208-17.
Lee JM, Yanagawa J, Peebles KA, Sharma S, Mao JT, Dubinett SM. PMID: 18304833; PMCID: PMC2483429.
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PubMed Mentions:
56 Fields:
Translation:
HumansCells
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Inflammation, epithelial to mesenchymal transition, and epidermal growth factor receptor tyrosine kinase inhibitor resistance. J Thorac Oncol. 2008 Feb; 3(2):107-10.
Krysan K, Lee JM, Dohadwala M, Gardner BK, Reckamp KL, Garon E, St John M, Sharma S, Dubinett SM. PMID: 18303428.
View in:
PubMed Mentions:
21 Fields:
Translation:
HumansCells
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Tumor response to combination celecoxib and erlotinib therapy in non-small cell lung cancer is associated with a low baseline matrix metalloproteinase-9 and a decline in serum-soluble E-cadherin. J Thorac Oncol. 2008 Feb; 3(2):117-24.
Reckamp KL, Gardner BK, Figlin RA, Elashoff D, Krysan K, Dohadwala M, Mao J, Sharma S, Inge L, Rajasekaran A, Dubinett SM. PMID: 18303430.
View in:
PubMed Mentions:
23 Fields:
Translation:
HumansCTClinical Trials
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Evaluation of [(18)F]gefitinib as a molecular imaging probe for the assessment of the epidermal growth factor receptor status in malignant tumors. Eur J Nucl Med Mol Imaging. 2008 Jun; 35(6):1089-99.
Su H, Seimbille Y, Ferl GZ, Bodenstein C, Fueger B, Kim KJ, Hsu YT, Dubinett SM, Phelps ME, Czernin J, Weber WA. PMID: 18239919.
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PubMed Mentions:
48 Fields:
Translation:
AnimalsCells
-
The Role of PPARgamma in the Cyclooxygenase Pathway in Lung Cancer. PPAR Res. 2008; 2008:790568.
Hazra S, Peebles KA, Sharma S, Mao JT, Dubinett SM. PMID: 18769553; PMCID: PMC2526169.
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PubMed Mentions:
14
-
Inflammation and lung carcinogenesis: applying findings in prevention and treatment. Expert Rev Anticancer Ther. 2007 Oct; 7(10):1405-21.
Peebles KA, Lee JM, Mao JT, Hazra S, Reckamp KL, Krysan K, Dohadwala M, Heinrich EL, Walser TC, Cui X, Baratelli FE, Garon E, Sharma S, Dubinett SM. PMID: 17944566.
View in:
PubMed Mentions:
36 Fields:
Translation:
HumansAnimals
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Ciglitazone mediates COX-2 dependent suppression of PGE2 in human non-small cell lung cancer cells. Prostaglandins Leukot Essent Fatty Acids. 2007 Jul; 77(1):51-8.
Hazra S, Dubinett SM. PMID: 17697767; PMCID: PMC2045645.
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PubMed Mentions:
15 Fields:
Translation:
HumansCells
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EGFR signaling is required for TGF-beta 1 mediated COX-2 induction in human bronchial epithelial cells. Am J Respir Cell Mol Biol. 2007 Nov; 37(5):578-88.
Liu M, Yang SC, Sharma S, Luo J, Cui X, Peebles KA, Huang M, Sato M, Ramirez RD, Shay JW, Minna JD, Dubinett SM. PMID: 17600311; PMCID: PMC2048680.
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PubMed Mentions:
20 Fields:
Translation:
HumansCells
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Pioglitazone and rosiglitazone decrease prostaglandin E2 in non-small-cell lung cancer cells by up-regulating 15-hydroxyprostaglandin dehydrogenase. Mol Pharmacol. 2007 Jun; 71(6):1715-20.
Hazra S, Batra RK, Tai HH, Sharma S, Cui X, Dubinett SM. PMID: 17412838.
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PubMed Mentions:
40 Fields:
Translation:
HumansCells
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Significance of cyclooxygenase-2 in prognosis, targeted therapy and chemoprevention of NSCLC. Future Oncol. 2007 Apr; 3(2):149-53.
Lee JM, Mao JT, Krysan K, Dubinett SM. PMID: 17381414.
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PubMed Mentions:
7 Fields:
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Green tea induces annexin-I expression in human lung adenocarcinoma A549 cells: involvement of annexin-I in actin remodeling. Lab Invest. 2007 May; 87(5):456-65.
Lu QY, Jin YS, Zhang ZF, Le AD, Heber D, Li FP, Dubinett SM, Rao JY. PMID: 17351649.
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PubMed Mentions:
8 Fields:
Translation:
HumansAnimalsCells
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Monitoring tumor glucose utilization by positron emission tomography for the prediction of treatment response to epidermal growth factor receptor kinase inhibitors. Clin Cancer Res. 2006 Oct 01; 12(19):5659-67.
Su H, Bodenstein C, Dumont RA, Seimbille Y, Dubinett S, Phelps ME, Herschman H, Czernin J, Weber W. PMID: 17020967.
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PubMed Mentions:
82 Fields:
Translation:
HumansAnimalsCells
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Mixed metastatic lung cancer lesions in bone are inhibited by noggin overexpression and Rank:Fc administration. J Bone Miner Res. 2006 Oct; 21(10):1571-80.
Feeley BT, Liu NQ, Conduah AH, Krenek L, Roth K, Dougall WC, Huard J, Dubinett S, Lieberman JR. PMID: 16995812.
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PubMed Mentions:
43 Fields:
Translation:
HumansAnimalsCells
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Dendritic cell surface calreticulin is a receptor for NY-ESO-1: direct interactions between tumor-associated antigen and the innate immune system. J Immunol. 2006 Sep 15; 177(6):3582-9.
Zeng G, Aldridge ME, Tian X, Seiler D, Zhang X, Jin Y, Rao J, Li W, Chen D, Langford MP, Duggan C, Belldegrun AS, Dubinett SM. PMID: 16951317.
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PubMed Mentions:
26 Fields:
Translation:
HumansCells
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Progress in chemoprevention drug development: the promise of molecular biomarkers for prevention of intraepithelial neoplasia and cancer--a plan to move forward. Clin Cancer Res. 2006 Jun 15; 12(12):3661-97.
Kelloff GJ, Lippman SM, Dannenberg AJ, Sigman CC, Pearce HL, Reid BJ, Szabo E, Jordan VC, Spitz MR, Mills GB, Papadimitrakopoulou VA, Lotan R, Aggarwal BB, Bresalier RS, Kim J, Arun B, Lu KH, Thomas ME, Rhodes HE, Brewer MA, Follen M, Shin DM, Parnes HL, Siegfried JM, Evans AA, Blot WJ, Chow WH, Blount PL, Maley CC, Wang KK, Lam S, Lee JJ, Dubinett SM, Engstrom PF, Meyskens FL, O'Shaughnessy J, Hawk ET, Levin B, Nelson WG, Hong WK, AACR Task Force on Cancer Prevention. PMID: 16778094.
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PubMed Mentions:
90 Fields:
Translation:
HumansCells
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A phase I trial to determine the optimal biological dose of celecoxib when combined with erlotinib in advanced non-small cell lung cancer. Clin Cancer Res. 2006 Jun 01; 12(11 Pt 1):3381-8.
Reckamp KL, Krysan K, Morrow JD, Milne GL, Newman RA, Tucker C, Elashoff RM, Dubinett SM, Figlin RA. PMID: 16740761.
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PubMed Mentions:
38 Fields:
Translation:
HumansCTClinical Trials
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Cyclooxygenase-2-dependent regulation of E-cadherin: prostaglandin E(2) induces transcriptional repressors ZEB1 and snail in non-small cell lung cancer. Cancer Res. 2006 May 15; 66(10):5338-45.
Dohadwala M, Yang SC, Luo J, Sharma S, Batra RK, Huang M, Lin Y, Goodglick L, Krysan K, Fishbein MC, Hong L, Lai C, Cameron RB, Gemmill RM, Drabkin HA, Dubinett SM. PMID: 16707460.
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PubMed Mentions:
132 Fields:
Translation:
HumansCells
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The potential and rationale for COX-2 inhibitors in lung cancer. Anticancer Agents Med Chem. 2006 May; 6(3):209-20.
Krysan K, Reckamp KL, Sharma S, Dubinett SM. PMID: 16712449.
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PubMed Mentions:
31 Fields:
Translation:
HumansAnimals
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IL-4 regulates COX-2 and PGE2 production in human non-small cell lung cancer. Biochem Biophys Res Commun. 2006 May 19; 343(4):995-1001.
Cui X, Yang SC, Sharma S, Heuze-Vourc'h N, Dubinett SM. PMID: 16574063.
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PubMed Mentions:
10 Fields:
Translation:
HumansCells
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Intrapulmonary administration of CCL21 gene-modified dendritic cells reduces tumor burden in spontaneous murine bronchoalveolar cell carcinoma. Cancer Res. 2006 Mar 15; 66(6):3205-13.
Yang SC, Batra RK, Hillinger S, Reckamp KL, Strieter RM, Dubinett SM, Sharma S. PMID: 16540672.
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PubMed Mentions:
43 Fields:
Translation:
AnimalsCells
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Oncogenic RAS mutations in myeloma cells selectively induce cox-2 expression, which participates in enhanced adhesion to fibronectin and chemoresistance. Blood. 2006 Jun 01; 107(11):4484-90.
Hoang B, Zhu L, Shi Y, Frost P, Yan H, Sharma S, Sharma S, Goodglick L, Dubinett S, Lichtenstein A. PMID: 16497971; PMCID: PMC1895799.
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PubMed Mentions:
15 Fields:
Translation:
HumansCells
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CXCR3/CXCR3 ligand biological axis impairs RENCA tumor growth by a mechanism of immunoangiostasis. J Immunol. 2006 Feb 01; 176(3):1456-64.
Pan J, Burdick MD, Belperio JA, Xue YY, Gerard C, Sharma S, Dubinett SM, Strieter RM. PMID: 16424173.
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PubMed Mentions:
53 Fields:
Translation:
AnimalsCells
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Celecoxib decreases Ki-67 proliferative index in active smokers. Clin Cancer Res. 2006 Jan 01; 12(1):314-20.
Mao JT, Fishbein MC, Adams B, Roth MD, Goodglick L, Hong L, Burdick M, Strieter ER, Holmes C, Tashkin DP, Dubinett SM. PMID: 16397057.
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PubMed Mentions:
18 Fields:
Translation:
HumansCTClinical Trials
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Aromatase inhibitors in human lung cancer therapy. Cancer Res. 2005 Dec 15; 65(24):11287-91.
Weinberg OK, Marquez-Garban DC, Fishbein MC, Goodglick L, Garban HJ, Dubinett SM, Pietras RJ. PMID: 16357134.
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PubMed Mentions:
81 Fields:
Translation:
HumansAnimals
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Cyclooxygenase-2-dependent activation of signal transducer and activator of transcription 3 by interleukin-6 in non-small cell lung cancer. Clin Cancer Res. 2005 Nov 01; 11(21):7674-82.
Dalwadi H, Krysan K, Heuze-Vourc'h N, Dohadwala M, Elashoff D, Sharma S, Cacalano N, Lichtenstein A, Dubinett S. PMID: 16278387.
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PubMed Mentions:
54 Fields:
Translation:
HumansCells
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COX-2 inhibition affects growth rate of Chlamydia muridarum within epithelial cells. Microbes Infect. 2006 Feb; 8(2):478-86.
Liu W, Dubinett S, Patterson SL, Kelly KA. PMID: 16297651.
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PubMed Mentions:
12 Fields:
Translation:
HumansAnimalsCells
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Arginase I in myeloid suppressor cells is induced by COX-2 in lung carcinoma. J Exp Med. 2005 Oct 03; 202(7):931-9.
Rodriguez PC, Hernandez CP, Quiceno D, Dubinett SM, Zabaleta J, Ochoa JB, Gilbert J, Ochoa AC. PMID: 16186186; PMCID: PMC2213169.
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PubMed Mentions:
280 Fields:
Translation:
AnimalsCells
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Prostaglandin E2 induces FOXP3 gene expression and T regulatory cell function in human CD4+ T cells. J Immunol. 2005 Aug 01; 175(3):1483-90.
Baratelli F, Lin Y, Zhu L, Yang SC, Heuzé-Vourc'h N, Zeng G, Reckamp K, Dohadwala M, Sharma S, Dubinett SM. PMID: 16034085.
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PubMed Mentions:
222 Fields:
Translation:
HumansCells
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IL-20, an anti-angiogenic cytokine that inhibits COX-2 expression. Biochem Biophys Res Commun. 2005 Jul 29; 333(2):470-5.
Heuzé-Vourc'h N, Liu M, Dalwadi H, Baratelli FE, Zhu L, Goodglick L, Põld M, Sharma S, Ramirez RD, Shay JW, Minna JD, Strieter RM, Dubinett SM. PMID: 15950941.
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PubMed Mentions:
12 Fields:
Translation:
HumansCells
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Prostaglandin E2 activates mitogen-activated protein kinase/Erk pathway signaling and cell proliferation in non-small cell lung cancer cells in an epidermal growth factor receptor-independent manner. Cancer Res. 2005 Jul 15; 65(14):6275-81.
Krysan K, Reckamp KL, Dalwadi H, Sharma S, Rozengurt E, Dohadwala M, Dubinett SM. PMID: 16024629.
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PubMed Mentions:
92 Fields:
Translation:
HumansCells
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Cyclooxygenase 2 inhibition promotes IFN-gamma-dependent enhancement of antitumor responses. J Immunol. 2005 Jul 15; 175(2):813-9.
Sharma S, Zhu L, Yang SC, Zhang L, Lin J, Hillinger S, Gardner B, Reckamp K, Strieter RM, Huang M, Batra RK, Dubinett SM. PMID: 16002678.
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PubMed Mentions:
18 Fields:
Translation:
AnimalsCells
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Chemoprevention strategies with cyclooxygenase-2 inhibitors for lung cancer. Clin Lung Cancer. 2005 Jul; 7(1):30-9.
Mao JT, Cui X, Reckamp K, Liu M, Krysan K, Dalwadi H, Sharma S, Hazra S, Strieter R, Gardner B, Dubinett SM. PMID: 16098242.
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PubMed Mentions:
16 Fields:
Translation:
HumansCells
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Tumor cyclooxygenase-2/prostaglandin E2-dependent promotion of FOXP3 expression and CD4+ CD25+ T regulatory cell activities in lung cancer. Cancer Res. 2005 Jun 15; 65(12):5211-20.
Sharma S, Yang SC, Zhu L, Reckamp K, Gardner B, Baratelli F, Huang M, Batra RK, Dubinett SM. PMID: 15958566.
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PubMed Mentions:
197 Fields:
Translation:
AnimalsCells
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PGE2 confers survivin-dependent apoptosis resistance in human monocyte-derived dendritic cells. J Leukoc Biol. 2005 Aug; 78(2):555-64.
Baratelli F, Krysan K, Heuzé-Vourc'h N, Zhu L, Escuadro B, Sharma S, Reckamp K, Dohadwala M, Dubinett SM. PMID: 15908458.
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PubMed Mentions:
21 Fields:
Translation:
HumansCells
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Dominant B cell epitope from NY-ESO-1 recognized by sera from a wide spectrum of cancer patients: implications as a potential biomarker. Int J Cancer. 2005 Mar 20; 114(2):268-73.
Zeng G, Aldridge ME, Wang Y, Pantuck AJ, Wang AY, Liu YX, Han Y, Yuan YH, Robbins PF, Dubinett SM, deKernion JB, Belldegrun AS. PMID: 15540228.
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PubMed Mentions:
16 Fields:
Translation:
HumansCells
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The effect of cyclooxygenase-2 (COX-2) inhibition on human prostate cancer induced osteoblastic and osteolytic lesions in bone. Anticancer Res. 2005 Jan-Feb; 25(1A):107-15.
Gamradt SC, Feeley BT, Liu NQ, Roostaeian J, Lin YQ, Zhu LX, Sharma S, Dubinett SM, Lieberman JR. PMID: 15816526.
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PubMed Mentions:
6 Fields:
Translation:
HumansAnimalsCells
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CXC chemokines: angiogenesis, immunoangiostasis, and metastases in lung cancer. Ann N Y Acad Sci. 2004 Dec; 1028:351-60.
Strieter RM, Belperio JA, Burdick MD, Sharma S, Dubinett SM, Keane MP. PMID: 15650260.
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PubMed Mentions:
40 Fields:
Translation:
HumansAnimalsCells
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Prostaglandin E2-dependent enhancement of tissue inhibitors of metalloproteinases-1 production limits dendritic cell migration through extracellular matrix. J Immunol. 2004 Nov 01; 173(9):5458-66.
Baratelli FE, Heuzé-Vourc'h N, Krysan K, Dohadwala M, Riedl K, Sharma S, Dubinett SM. PMID: 15494493.
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PubMed Mentions:
22 Fields:
Translation:
HumansCells
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Modulation of pulmonary leukotriene B4 production by cyclooxygenase-2 inhibitors and lipopolysaccharide. Clin Cancer Res. 2004 Oct 15; 10(20):6872-8.
Mao JT, Tsu IH, Dubinett SM, Adams B, Sarafian T, Baratelli F, Roth MD, Serio KJ. PMID: 15501964.
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PubMed Mentions:
17 Fields:
Translation:
HumansCellsCTClinical Trials
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Cyclooxygenase 2-dependent expression of survivin is critical for apoptosis resistance in non-small cell lung cancer. Cancer Res. 2004 Sep 15; 64(18):6359-62.
Krysan K, Dalwadi H, Sharma S, Põld M, Dubinett S. PMID: 15374938.
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PubMed Mentions:
39 Fields:
Translation:
HumansCells
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Cyclooxygenase-2 modulates the insulin-like growth factor axis in non-small-cell lung cancer. Cancer Res. 2004 Sep 15; 64(18):6549-55.
Põld M, Krysan K, Põld A, Dohadwala M, Heuze-Vourc'h N, Mao JT, Riedl KL, Sharma S, Dubinett SM. PMID: 15374967.
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PubMed Mentions:
16 Fields:
Translation:
HumansCells
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Assessing prognosis in non-small-cell lung cancer: avenues to a more complete picture? J Clin Oncol. 2004 Aug 15; 22(16):3209-11.
Dubinett SM, Elashoff D, Meyerson M. PMID: 15249586.
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PubMed Mentions:
1 Fields:
Translation:
Humans
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Multifaceted roles of cyclooxygenase-2 in lung cancer. Drug Resist Updat. 2004 Jun; 7(3):169-84.
Riedl K, Krysan K, Põld M, Dalwadi H, Heuze-Vourc'h N, Dohadwala M, Liu M, Cui X, Figlin R, Mao JT, Strieter R, Sharma S, Dubinett SM. PMID: 15296859.
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PubMed Mentions:
33 Fields:
Translation:
HumansCells
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Interleukin-7 and transforming growth factor-beta play counter-regulatory roles in protein kinase C-delta-dependent control of fibroblast collagen synthesis in pulmonary fibrosis. J Biol Chem. 2004 Jul 02; 279(27):28315-9.
Zhang L, Keane MP, Zhu LX, Sharma S, Rozengurt E, Strieter RM, Dubinett SM, Huang M. PMID: 15133032.
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PubMed Mentions:
19 Fields:
Translation:
HumansCells
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Cyclooxygenase-2-dependent expression of survivin in non-small cell lung cancer. Chest. 2004 May; 125(5 Suppl):140S.
Krysan K, Dohadwala M, Luo J, Lin Y, Zhu L, Heuze-Vourc'h N, Goodglick L, Merchant F, Seligson D, Pold M, Strieter R, Sharma S, Dubinett S. PMID: 15136466.
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PubMed Mentions:
1 Fields:
Translation:
HumansAnimalsCells
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Intratumoral administration of dendritic cells overexpressing CCL21 generates systemic antitumor responses and confers tumor immunity. Clin Cancer Res. 2004 Apr 15; 10(8):2891-901.
Yang SC, Hillinger S, Riedl K, Zhang L, Zhu L, Huang M, Atianzar K, Kuo BY, Gardner B, Batra RK, Strieter RM, Dubinett SM, Sharma S. PMID: 15102698.
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PubMed Mentions:
57 Fields:
Translation:
AnimalsCells
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COX-2 inhibition and lung cancer. Semin Oncol. 2004 Apr; 31(2 Suppl 7):45-52.
Sandler AB, Dubinett SM. PMID: 15179623.
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PubMed Mentions:
45 Fields:
Translation:
HumansAnimals
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Cyclooxygenase-2-dependent expression of angiogenic CXC chemokines ENA-78/CXC Ligand (CXCL) 5 and interleukin-8/CXCL8 in human non-small cell lung cancer. Cancer Res. 2004 Mar 01; 64(5):1853-60.
Põld M, Zhu LX, Sharma S, Burdick MD, Lin Y, Lee PP, Põld A, Luo J, Krysan K, Dohadwala M, Mao JT, Batra RK, Strieter RM, Dubinett SM. PMID: 14996749.
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PubMed Mentions:
50 Fields:
Translation:
HumansAnimalsCells
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Cocaine modulates cytokine and enhances tumor growth through sigma receptors. J Neuroimmunol. 2004 Feb; 147(1-2):95-8.
Gardner B, Zhu LX, Roth MD, Tashkin DP, Dubinett SM, Sharma S. PMID: 14741436.
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PubMed Mentions:
19 Fields:
Translation:
AnimalsCells
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EBV-induced molecule 1 ligand chemokine (ELC/CCL19) promotes IFN-gamma-dependent antitumor responses in a lung cancer model. J Immunol. 2003 Dec 15; 171(12):6457-65.
Hillinger S, Yang SC, Zhu L, Huang M, Duckett R, Atianzar K, Batra RK, Strieter RM, Dubinett SM, Sharma S. PMID: 14662845.
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PubMed Mentions:
29 Fields:
Translation:
AnimalsCells
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Celecoxib modulates the capacity for prostaglandin E2 and interleukin-10 production in alveolar macrophages from active smokers. Clin Cancer Res. 2003 Dec 01; 9(16 Pt 1):5835-41.
Mao JT, Roth MD, Serio KJ, Baratelli F, Zhu L, Holmes EC, Strieter RM, Dubinett SM. PMID: 14676104.
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PubMed Mentions:
9 Fields:
Translation:
HumansCells
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COX-2-dependent stabilization of survivin in non-small cell lung cancer. FASEB J. 2004 Jan; 18(1):206-8.
Krysan K, Merchant FH, Zhu L, Dohadwala M, Luo J, Lin Y, Heuze-Vourc'h N, Põld M, Seligson D, Chia D, Goodglick L, Wang H, Strieter R, Sharma S, Dubinett S. PMID: 14597555.
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PubMed Mentions:
48 Fields:
Translation:
HumansAnimalsCells
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Overexpression of CCL-21/secondary lymphoid tissue chemokine in human dendritic cells augments chemotactic activities for lymphocytes and antigen presenting cells. Mol Cancer. 2003 Nov 02; 2:35.
Riedl K, Baratelli F, Batra RK, Yang SC, Luo J, Escuadro B, Figlin R, Strieter R, Sharma S, Dubinett S. PMID: 14613584; PMCID: PMC270078.
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PubMed Mentions:
14 Fields:
Translation:
HumansCells
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Interleukin-7 gene-modified dendritic cells reduce pulmonary tumor burden in spontaneous murine bronchoalveolar cell carcinoma. Hum Gene Ther. 2003 Nov 01; 14(16):1511-24.
Sharma S, Batra RK, Yang SC, Hillinger S, Zhu L, Atianzar K, Strieter RM, Riedl K, Huang M, Dubinett SM. PMID: 14577913; PMCID: PMC1471881.
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PubMed Mentions:
16 Fields:
Translation:
AnimalsCells
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Methanandamide increases COX-2 expression and tumor growth in murine lung cancer. FASEB J. 2003 Nov; 17(14):2157-9.
Gardner B, Zhu LX, Sharma S, Tashkin DP, Dubinett SM. PMID: 12958151.
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PubMed Mentions:
15 Fields:
Translation:
Animals
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Nonradioactive iodide effectively induces apoptosis in genetically modified lung cancer cells. Cancer Res. 2003 Aug 15; 63(16):5065-72.
Zhang L, Sharma S, Zhu LX, Kogai T, Hershman JM, Brent GA, Dubinett SM, Huang M. PMID: 12941836.
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PubMed Mentions:
13 Fields:
Translation:
HumansAnimalsCells
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SLC/CCL21-mediated anti-tumor responses require IFNgamma, MIG/CXCL9 and IP-10/CXCL10. Mol Cancer. 2003 Apr 15; 2:22.
Sharma S, Yang SC, Hillinger S, Zhu LX, Huang M, Batra RK, Lin JF, Burdick MD, Strieter RM, Dubinett SM. PMID: 12740040; PMCID: PMC155639.
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PubMed Mentions:
36 Fields:
Translation:
AnimalsCells
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IL-10 mediates sigma 1 receptor-dependent suppression of antitumor immunity. J Immunol. 2003 Apr 01; 170(7):3585-91.
Zhu LX, Sharma S, Gardner B, Escuadro B, Atianzar K, Tashkin DP, Dubinett SM. PMID: 12646621.
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PubMed Mentions:
22 Fields:
Translation:
AnimalsCells
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Tumor cyclooxygenase 2-dependent suppression of dendritic cell function. Clin Cancer Res. 2003 Mar; 9(3):961-8.
Sharma S, Stolina M, Yang SC, Baratelli F, Lin JF, Atianzar K, Luo J, Zhu L, Lin Y, Huang M, Dohadwala M, Batra RK, Dubinett SM. PMID: 12631593.
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PubMed Mentions:
76 Fields:
Translation:
AnimalsCells
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Abnormal interleukin 10Ralpha expression contributes to the maintenance of elevated cyclooxygenase-2 in non-small cell lung cancer cells. Cancer Res. 2003 Feb 15; 63(4):766-70.
Heuze-Vourc'h N, Zhu L, Krysan K, Batra RK, Sharma S, Dubinett SM. PMID: 12591723.
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PubMed Mentions:
6 Fields:
Translation:
HumansCells
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Non-small cell lung cancer-derived soluble mediators enhance apoptosis in activated T lymphocytes through an I kappa B kinase-dependent mechanism. Cancer Res. 2003 Feb 01; 63(3):642-6.
Batra RK, Lin Y, Sharma S, Dohadwala M, Luo J, Pold M, Dubinett SM. PMID: 12566308.
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PubMed Mentions:
7 Fields:
Translation:
HumansCells
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Intratumoral therapy with cytokine gene-modified dendritic cells in murine lung cancer models. Methods Mol Med. 2003; 75:711-22.
Sharma S, Yang SC, Batra RK, Dubinett SM. PMID: 12407774.
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PubMed Mentions:
2 Fields:
Translation:
AnimalsCells
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Cyclooxygenase 2-dependent regulation of antitumor immunity in lung cancer. Methods Mol Med. 2003; 75:723-36.
Sharma S, Huang M, Dohadwala M, Pold M, Batra RK, Dubinett SM. PMID: 12407775.
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PubMed Mentions:
1 Fields:
Translation:
AnimalsCells
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Cyclooxygenase-2 in lung cancer. Prog Exp Tumor Res. 2003; 37:138-62.
Dubinett SM, Sharma S, Huang M, Dohadwala M, Pold M, Mao JT. PMID: 12795053.
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PubMed Mentions:
9 Fields:
Translation:
HumansAnimalsCells
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Respiratory and immunologic consequences of marijuana smoking. J Clin Pharmacol. 2002 11; 42(S1):71S-81S.
Tashkin DP, Baldwin GC, Sarafian T, Dubinett S, Roth MD. PMID: 12412839.
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PubMed Mentions:
65 Fields:
Translation:
HumansCells
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Autocrine/paracrine prostaglandin E2 production by non-small cell lung cancer cells regulates matrix metalloproteinase-2 and CD44 in cyclooxygenase-2-dependent invasion. J Biol Chem. 2002 Dec 27; 277(52):50828-33.
Dohadwala M, Batra RK, Luo J, Lin Y, Krysan K, Pold M, Sharma S, Dubinett SM. PMID: 12393872; PMCID: PMC1471886.
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PubMed Mentions:
76 Fields:
Translation:
HumansCells
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Soluble coxsackievirus adenovirus receptor is a putative inhibitor of adenoviral gene transfer in the tumor milieu. Clin Cancer Res. 2002 Jun; 8(6):1915-23.
Bernal RM, Sharma S, Gardner BK, Douglas JT, Bergelson JM, Dubinett SM, Batra RK. PMID: 12060636.
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PubMed Mentions:
8 Fields:
Translation:
HumansAnimalsCells
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Increased dendritic cell number and function following continuous in vivo infusion of granulocyte macrophage-colony-stimulating factor and interleukin-4. Blood. 2002 Apr 15; 99(8):2869-79.
Basak SK, Harui A, Stolina M, Sharma S, Mitani K, Dubinett SM, Roth MD. PMID: 11929777.
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PubMed Mentions:
17 Fields:
Translation:
AnimalsCells
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IL-7 inhibits fibroblast TGF-beta production and signaling in pulmonary fibrosis. J Clin Invest. 2002 Apr; 109(7):931-7.
Huang M, Sharma S, Zhu LX, Keane MP, Luo J, Zhang L, Burdick MD, Lin YQ, Dohadwala M, Gardner B, Batra RK, Strieter RM, Dubinett SM. PMID: 11927620; PMCID: PMC150933.
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PubMed Mentions:
70 Fields:
Translation:
HumansAnimalsCells
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Autocrine and paracrine regulation of lymphocyte CB2 receptor expression by TGF-beta. Biochem Biophys Res Commun. 2002 Jan 11; 290(1):91-6.
Gardner B, Zu LX, Sharma S, Liu Q, Makriyannis A, Tashkin DP, Dubinett SM. PMID: 11779138.
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PubMed Mentions:
22 Fields:
Translation:
HumansCells
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Intratumoral administration of adenoviral interleukin 7 gene-modified dendritic cells augments specific antitumor immunity and achieves tumor eradication. Hum Gene Ther. 2000 Jan 01; 11(1):53-65.
Miller PW, Sharma S, Stolina M, Butterfield LH, Luo J, Lin Y, Dohadwala M, Batra RK, Wu L, Economou JS, Dubinett SM. PMID: 10646639.
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PubMed Mentions:
30 Fields:
Translation:
AnimalsCells
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A comparison of gene transfer methods in human dendritic cells. Cancer Gene Ther. 1997 Jan-Feb; 4(1):17-25.
Arthur JF, Butterfield LH, Roth MD, Bui LA, Kiertscher SM, Lau R, Dubinett S, Glaspy J, McBride WH, Economou JS. PMID: 9012447.
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PubMed Mentions:
45 Fields:
Translation:
HumansCells
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Interleukin-7 gene transfer in non-small-cell lung cancer decreases tumor proliferation, modifies cell surface molecule expression, and enhances antitumor reactivity. Cancer Gene Ther. 1996 Sep-Oct; 3(5):302-13.
Sharma S, Wang J, Huang M, Paul RW, Lee P, McBride WH, Economou JS, Roth MD, Kiertscher SM, Dubinett SM. PMID: 8894249.
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PubMed Mentions:
6 Fields:
Translation:
HumansCells
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Down-regulation of murine fibrosarcoma transforming growth factor-beta 1 expression by interleukin 7. J Natl Cancer Inst. 1995 Apr 19; 87(8):593-7.
Dubinett SM, Huang M, Dhanani S, Economou JS, Wang J, Lee P, Sharma S, Dougherty GJ, McBride WH. PMID: 7752257.
View in:
PubMed Mentions:
10 Fields:
Translation:
AnimalsCells
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Cytokine immunotherapy of non-small cell lung cancer. Reg Immunol. 1993 May-Aug; 5(3-4):232-43.
Dubinett SM, Kradin RL. PMID: 8240940.
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PubMed Mentions:
1 Fields:
Translation:
HumansCells
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Interleukin-2-responsive wound-infiltrating lymphocytes in surgical adjuvant cancer immunotherapy. Immunol Invest. 1993 Feb; 22(1):13-23.
Dubinett SM, Patrone L, Huang M, Markowitz J, McBride WH, Economou JS, Tobias J, Kelley D, Yan D, Seelig M. PMID: 8440522.
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Effects of tumor necrosis factor-alpha on peroxidation of plasma lipoprotein lipids in experimental animals and patients. Blood. 1992 Dec 15; 80(12):3217-26.
McDonagh J, Fossel ET, Kradin RL, Dubinett SM, Laposata M, Hallaq YA. PMID: 1467525.
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Genetic modification of a murine fibrosarcoma to produce interleukin 7 stimulates host cell infiltration and tumor immunity. Cancer Res. 1992 Jul 15; 52(14):3931-7.
McBride WH, Thacker JD, Comora S, Economou JS, Kelley D, Hogge D, Dubinett SM, Dougherty GJ. PMID: 1617669.
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Cytokine administration alters the distribution of activated lymphocytes to the lung. Pathobiology. 1991; 59(6):372-7.
Dubinett SM, Callahan RJ, Xia WJ, Ahmad M, Strauss HW, Kradin RL. PMID: 1930689.
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Adoptive immunotherapy of murine pulmonary metastases with interleukin 2 and interferon-gamma. Am J Respir Cell Mol Biol. 1989 Nov; 1(5):361-9.
Dubinett SM, Kurnick JT, Kradin RL. PMID: 2517774.
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Efficacy of adjuvant interleukin-2 after excision of BALB/c fibrosarcomas. Surgery. 1989 Aug; 106(2):120-5.
Gallagher WJ, Dubinett SM, Hoover HC, Kradin RL. PMID: 2788315.
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Animals
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Tumour-infiltrating lymphocytes and interleukin-2 in treatment of advanced cancer. Lancet. 1989 Mar 18; 1(8638):577-80.
Kradin RL, Kurnick JT, Lazarus DS, Preffer FI, Dubinett SM, Pinto CE, Gifford J, Davidson E, Grove B, Callahan RJ, et al. PMID: 2564111.
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HumansCellsCTClinical Trials
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Adoptive immunotherapy with IL-2 results in the loss of delayed-type hypersensitivity responses and the development of immediate hypersensitivity to recall antigens. Clin Immunol Immunopathol. 1989 Feb; 50(2):184-95.
Kradin RL, Kurnick JT, Preffer FI, Dubinett SM, Dickersin GR, Pinto C. PMID: 2783665.
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3 Fields:
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Treatment of patients with advanced cancer using tumor-infiltrating lymphocytes and interleukin 2. Transplant Proc. 1988 Apr; 20(2):336-8.
Kradin R, Dubinett S, Mullin J, Boyle L, Strauss HW, Bourgoin PM, Preffer FI, Kurnick J. PMID: 3259036.
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4 Fields:
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Tumor-derived interleukin-2-dependent lymphocytes in adoptive immunotherapy of lung cancer. Cancer Immunol Immunother. 1987; 24(1):76-85.
Kradin RL, Boyle LA, Preffer FI, Callahan RJ, Barlai-Kovach M, Strauss HW, Dubinett S, Kurnick JT. PMID: 3493073; PMCID: PMC11038966.
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