Dorthe Schaue

Title(s)Adjunct Professor, Radiation Oncology
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    Acute radiation injury alters microRNA profiles that predict late tissue-specific damage
    NIH U01AI148322Feb 1, 2020 - Jan 31, 2025
    Role: Principal Investigator
    Visualizing radiation-induced tumor immune responses
    NIH R21CA228542Apr 5, 2019 - Mar 31, 2021
    Role: Co-Principal Investigator
    Myeloid reprogramming in response to acute radiation tissue damage
    NIH R01CA226875Mar 1, 2019 - Feb 29, 2024
    Role: Principal Investigator
    Radiotherapy-induced tumor immunity
    NIH R01CA191234Jul 1, 2015 - Jun 30, 2020
    Role: Principal Investigator

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. M2 isoform of pyruvate kinase rewires glucose metabolism during radiation therapy to promote an antioxidant response and glioblastoma radioresistance. Neuro Oncol. 2023 11 02; 25(11):1989-2000. Bailleul J, Ruan Y, Abdulrahman L, Scott AJ, Yazal T, Sung D, Park K, Hoang H, Nathaniel J, Chu FI, Palomera D, Sehgal A, Tsang JE, Nathanson DA, Xu S, Park JO, Ten Hoeve J, Bhat K, Qi N, Kornblum HI, Schaue D, McBride WH, Lyssiotis CA, Wahl DR, Vlashi E. PMID: 37279645; PMCID: PMC10628945.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    2. Total marrow irradiation reduces organ damage and enhances tissue repair with the potential to increase the targeted dose of bone marrow in both young and old mice. Front Oncol. 2022; 12:1045016. Lim JE, Sargur Madabushi S, Vishwasrao P, Song JY, Abdelhamid AMH, Ghimire H, Vanishree VL, Lamba JK, Dandapani S, Salhotra A, Lemecha M, Pierini A, Zhao D, Storme G, Holtan S, Aristei C, Schaue D, Al Malki M, Hui SK. PMID: 36439420; PMCID: PMC9686437.
      View in: PubMed   Mentions:
    3. Significant changes in macrophage and CD8 T cell densities in primary prostate tumors 2 weeks after SBRT. Prostate Cancer Prostatic Dis. 2023 03; 26(1):207-209. Kane N, Romero T, Diaz-Perez S, Rettig MB, Steinberg ML, Kishan AU, Schaue D, Reiter RE, Knudsen BS, Nickols NG. PMID: 35058580; PMCID: PMC10023555.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCells
    4. Use of constitutive and inducible oncogene-containing iPSCs as surrogates for transgenic mice to study breast oncogenesis. Stem Cell Res Ther. 2021 05 27; 12(1):301. Nguyen C, Nguyen JPT, Modi AP, Ahmad I, Petrova SC, Ferrell SD, Wilhelm SR, Ye Y, Schaue D, Barsky SH. PMID: 34044885; PMCID: PMC8162012.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    5. Phase 1 Trial of Stereotactic Body Radiation Therapy Neoadjuvant to Radical Prostatectomy for Patients With High-Risk Prostate Cancer. Int J Radiat Oncol Biol Phys. 2020 11 15; 108(4):930-935. Parikh NR, Kishan AU, Kane N, Diaz-Perez S, Ganapathy E, Nazarian R, Felix C, Mathis C, Bradley M, Sachdeva A, Wyatt B, Basehart V, Zomorodian N, Lin L, King CR, Kupelian PA, Rettig MB, Steinberg ML, Cao M, Knudsen BS, Elashoff D, Schaue D, Reiter RE, Nickols NG. PMID: 32562839; PMCID: PMC8261839.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCTClinical Trials
    6. Irradiation to Improve the Response to Immunotherapeutic Agents in Glioblastomas. Adv Radiat Oncol. 2019 Apr-Jun; 4(2):268-282. Nesseler JP, Schaue D, McBride WH, Lee MH, Kaprealian T, Niclou SP, Nickers P. PMID: 31011672; PMCID: PMC6460102.
      View in: PubMed   Mentions: 9  
    7. [Inflammatory and immune biomarkers of radiation response]. Cancer Radiother. 2018 Apr; 22(2):180-192. Nesseler JP, Schaue D, McBride WH, Nickers P. PMID: 29650389.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    8. Use of a Novel Polymer in an Animal Model of Head and Neck Squamous Cell Carcinoma. Otolaryngol Head Neck Surg. 2018 01; 158(1):110-117. Pellionisz PA, Lin Y, Mallen-St Clair J, Luo J, Suwarnasarn A, Schaue D, Elashoff DA, Palma-Diaz F, Dubinett SM, Sharma S, Wu B, St John MA. PMID: 28895464.
      View in: PubMed   Mentions: 4     Fields:    Translation:Animals
    9. Pro-inflammatory State Portends Poor Outcomes with Stereotactic Radiosurgery for Brain Metastases. Anticancer Res. 2016 10; 36(10):5333-5337. Shaverdian N, Wang J, Levin-Epstein R, Schaue D, Kupelian P, Lee P, Yang I, Kaprealian T. PMID: 27798896.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansCells
    10. Changes in Imaging and Cognition in Juvenile Rats After Whole-Brain Irradiation. Int J Radiat Oncol Biol Phys. 2016 10 01; 96(2):470-478. Brown RJ, Jun BJ, Cushman JD, Nguyen C, Beighley AH, Blanchard J, Iwamoto K, Schaue D, Harris NG, Jentsch JD, Bluml S, McBride WH. PMID: 27478168; PMCID: PMC5563160.
      View in: PubMed   Mentions: 2     Fields:    Translation:Animals
    11. Pretreatment Immune Parameters Predict for Overall Survival and Toxicity in Early-Stage Non-Small-Cell Lung Cancer Patients Treated With Stereotactic Body Radiation Therapy. Clin Lung Cancer. 2016 Jan; 17(1):39-46. Shaverdian N, Veruttipong D, Wang J, Schaue D, Kupelian P, Lee P. PMID: 26372098.
      View in: PubMed   Mentions: 31     Fields:    Translation:HumansCells
    12. A cytokine-delivering polymer is effective in reducing tumor burden in a head and neck squamous cell carcinoma murine model. Otolaryngol Head Neck Surg. 2014 Sep; 151(3):447-53. Lin Y, Luo J, Zhu WE, Srivastava M, Schaue D, Elashoff DA, Dubinett SM, Sharma S, Wu B, St John MA. PMID: 24825873; PMCID: PMC4167678.
      View in: PubMed   Mentions: 2     Fields:    Translation:Animals
    13. Cytokines in radiobiological responses: a review. Radiat Res. 2012 Dec; 178(6):505-23. Schaue D, Kachikwu EL, McBride WH. PMID: 23106210; PMCID: PMC3723384.
      View in: PubMed   Mentions: 166     Fields:    Translation:HumansAnimals
    14. A novel modular polymer platform for the treatment of head and neck squamous cell carcinoma in an animal model. Arch Otolaryngol Head Neck Surg. 2012 Apr; 138(4):412-7. Hu D, Lau OD, Wang L, Wang G, Schaue D, Zhu L, Huang M, Lin Y, Dennis M, Abemayor E, Elashoff DA, Dubinett SM, McBride WH, Sharma S, Wu B, St John MA. PMID: 22508626; PMCID: PMC4167672.
      View in: PubMed   Mentions: 6     Fields:    Translation:Animals
    15. Maximizing tumor immunity with fractionated radiation. Int J Radiat Oncol Biol Phys. 2012 Jul 15; 83(4):1306-10. Schaue D, Ratikan JA, Iwamoto KS, McBride WH. PMID: 22208977; PMCID: PMC3337972.
      View in: PubMed   Mentions: 276     Fields:    Translation:AnimalsCells
    16. PGE(2) contributes to TGF-beta induced T regulatory cell function in human non-small cell lung cancer. Am J Transl Res. 2010 Jun 30; 2(4):356-67. Baratelli F, Lee JM, Hazra S, Lin Y, Walser TC, Schaue D, Pak PS, Elashoff D, Reckamp K, Zhang L, Fishbein MC, Sharma S, Dubinett SM. PMID: 20733946; PMCID: PMC2923860.
      View in: PubMed   Mentions: 31  
    17. FLT-PET imaging of radiation responses in murine tumors. Mol Imaging Biol. 2008 Nov-Dec; 10(6):325-34. Pan MH, Huang SC, Liao YP, Schaue D, Wang CC, Stout DB, Barrio JR, McBride WH. PMID: 18670825; PMCID: PMC2696488.
      View in: PubMed   Mentions: 9     Fields:    Translation:AnimalsCells
    18. Modification of the tumor microenvironment to enhance immunity. Front Biosci. 2007 May 01; 12:3576-600. Liao YP, Schaue D, McBride WH. PMID: 17485323.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansAnimalsCells
    19. Counteracting tumor radioresistance by targeting DNA repair. Mol Cancer Ther. 2005 Oct; 4(10):1548-50. Schaue D, McBride WH. PMID: 16227404.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansCells
    20. Radiation treatment of acute inflammation in mice. Int J Radiat Biol. 2005 Sep; 81(9):657-67. Schaue D, Jahns J, Hildebrandt G, Trott KR. PMID: 16368644.
      View in: PubMed   Mentions: 34     Fields:    Translation:Animals
    21. The effects of low-dose X-irradiation on the oxidative burst in stimulated macrophages. Int J Radiat Biol. 2002 Jul; 78(7):567-76. Schaue D, Marples B, Trott KR. PMID: 12079535.
      View in: PubMed   Mentions: 32     Fields:    Translation:AnimalsCells
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