Keisuke Steven Iwamoto

Title(s)Adjunct Professor, Radiation Oncology
SchoolMedicine
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    Collapse Research 
    Collapse Research Activities and Funding
    Exploiting multidrug resistance mechanisms to counter radiation toxicity
    NIH R01AI128739Aug 7, 2017 - Jul 31, 2022
    Role: Principal Investigator

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Low-dose mepolizumab is effective as an add-on therapy for treating long-lasting peripheral neuropathy in patients with eosinophilic granulomatosis with polyangiitis. Mod Rheumatol. 2022 Feb 28; 32(2):387-395. Nakamura Y, Fukutomi Y, Sekiya K, Kajiwara K, Kawasaki Y, Fujita N, Nagayama K, Iwata M, Iwamoto K, Yano K, Hamada Y, Watai K, Ryu K, Hayashi H, Kamide Y, Taniguchi M. PMID: 34910206.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    2. Classes of Drugs that Mitigate Radiation Syndromes. Front Pharmacol. 2021; 12:666776. Micewicz ED, Damoiseaux RD, Deng G, Gomez A, Iwamoto KS, Jung ME, Nguyen C, Norris AJ, Ratikan JA, Ruchala P, Sayre JW, Schaue D, Whitelegge JP, McBride WH. PMID: 34084139; PMCID: PMC8167044.
      View in: PubMed   Mentions:
    3. Autologous transplantation of multilayered fibroblast sheets prevents postoperative pancreatic fistula by regulating fibrosis and angiogenesis. Am J Transl Res. 2021; 13(3):1257-1268. Iwamoto K, Saito T, Takemoto Y, Ueno K, Yanagihara M, Furuya-Kondo T, Kurazumi H, Tanaka Y, Taura Y, Harada E, Hamano K. PMID: 33841654; PMCID: PMC8014429.
      View in: PubMed   Mentions: 3  
    4. Weak Magnetic Fields Enhance the Efficacy of Radiation Therapy. Adv Radiat Oncol. 2021 May-Jun; 6(3):100645. Iwamoto KS, Sandstrom RE, Bryan M, Liu Y, Elgart SR, Sheng K, Steinberg ML, McBride WH, Low DA. PMID: 33748547; PMCID: PMC7966835.
      View in: PubMed   Mentions:
    5. Identification of miRNA signatures associated with radiation-induced late lung injury in mice. PLoS One. 2020; 15(5):e0232411. Rogers CJ, Lukaszewicz AI, Yamada-Hanff J, Micewicz ED, Ratikan JA, Starbird MA, Miller TA, Nguyen C, Lee JT, Olafsen T, Iwamoto KS, McBride WH, Schaue D, Menon N. PMID: 32392259; PMCID: PMC7213687.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansAnimalsPHPublic Health
    6. University of California Replacement of Cesium Irradiators with Alternative Technologies. Health Phys. 2020 02; 118(2):209-214. MacKenzie C, Iwamoto KS, Smith K. PMID: 31869317.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    7. Pulmonary nocardiosis caused by Nocardia blacklokiae in an immunocompetent patient. Respir Med Case Rep. 2020; 29:101005. Ito Y, Tanigawa M, Yaguchi T, Toyoshima H, Iwamoto K, Nigi A, Itani H, Kondo S, Tokui T, Sasano H. PMID: 32025483; PMCID: PMC6997618.
      View in: PubMed   Mentions: 1  
    8. Patent foramen ovale and the platypnea-orthodeoxia syndrome detected by transesophageal echocardiography. J Echocardiogr. 2021 09; 19(3):179-180. Mori T, Takamura T, Yamagishi H, Iwamoto K, Unno K, Seko T, Kasai A. PMID: 31845159.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    9. Interstitial pneumonitis associated with dasatinib: two case reports and literature review. Respir Investig. 2019 Sep; 57(5):506-509. Ito Y, Tanigawa M, Iwamoto K, Nigi A, Itani H, Kondo S, Tokui T, Usui E, Tamaki S. PMID: 31311724.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    10. Association between Long-Term Second Malignancy Risk and Radiation: A Comprehensive Analysis of the Entire Surveillance, Epidemiology, and End Results Database (1973-2014). Adv Radiat Oncol. 2019 Oct-Dec; 4(4):738-747. Wang C, Kishan AU, Yu JB, Raldow A, King CR, Iwamoto KS, Chu FI, Steinberg ML, Kupelian PA. PMID: 31673667; PMCID: PMC6817555.
      View in: PubMed   Mentions: 2  
    11. Chronic Nodular Pulmonary Aspergillosis in a Patient with Rheumatoid Arthritis. Intern Med. 2019; 58(7):979-984. Ito Y, Tanigawa M, Takemura T, Iwamoto K, Nigi A, Sasano H, Itani H, Kondo S, Tokui T, Nakamura S, Miyazaki Y. PMID: 30930349; PMCID: PMC6478981.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimals
    12. The Aftermath of Surviving Acute Radiation Hematopoietic Syndrome and its Mitigation. Radiat Res. 2019 04; 191(4):323-334. Micewicz ED, Iwamoto KS, Ratikan JA, Nguyen C, Xie MW, Cheng G, Boxx GM, Deriu E, Damoiseaux RD, Whitelegge JP, Ruchala PP, Avetisyan R, Jung ME, Lawson G, Nemeth E, Ganz T, Sayre JW, McBride WH, Schaue D. PMID: 30730284; PMCID: PMC6482953.
      View in: PubMed   Mentions: 7     Fields:    Translation:AnimalsPHPublic Health
    13. Ovarian Metastases from ALK-rearranged Lung Adenocarcinoma: A Case Report and Literature Review. Intern Med. 2018 Nov 15; 57(22):3271-3275. Sasano H, Sekine A, Hirata T, Iwamoto K, Itou Y, Itani H, Kondou S, Tokui T, Tanigawa M. PMID: 29984766; PMCID: PMC6287983.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    14. Lung abscess caused by Streptococcus pneumoniae serotype 6B. Respir Med Case Rep. 2018; 23:71-73. Ito Y, Toyoshima H, Suzuki T, Iwamoto K, Sasano H, Itani H, Kondo S, Tanigawa M. PMID: 29487787; PMCID: PMC5805848.
      View in: PubMed   Mentions: 1  
    15. Defined Sensing Mechanisms and Signaling Pathways Contribute to the Global Inflammatory Gene Expression Output Elicited by Ionizing Radiation. Immunity. 2017 09 19; 47(3):421-434.e3. Purbey PK, Scumpia PO, Kim PJ, Tong AJ, Iwamoto KS, McBride WH, Smale ST. PMID: 28930658; PMCID: PMC5661954.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansAnimalsCells
    16. 4-(Nitrophenylsulfonyl)piperazines mitigate radiation damage to multiple tissues. PLoS One. 2017; 12(7):e0181577. Micewicz ED, Kim K, Iwamoto KS, Ratikan JA, Cheng G, Boxx GM, Damoiseaux RD, Whitelegge JP, Ruchala P, Nguyen C, Purbey P, Loo J, Deng G, Jung ME, Sayre JW, Norris AJ, Schaue D, McBride WH. PMID: 28732024; PMCID: PMC5521796.
      View in: PubMed   Mentions: 7     Fields:    Translation:AnimalsCellsPHPublic Health
    17. The relative accuracy of 4D dose accumulation for lung radiotherapy using rigid dose projection versus dose recalculation on every breathing phase. Med Phys. 2017 Mar; 44(3):1120-1127. Valdes G, Lee C, Tenn S, Lee P, Robinson C, Iwamoto K, Low D, Lamb JM. PMID: 28019649.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    18. Pattern of solid and hematopoietic second malignancy after local therapy for prostate cancer. Radiother Oncol. 2017 04; 123(1):133-138. Wang C, King CR, Kamrava M, Iwamoto KS, Chen AM, Low D, Kupelian PA, Steinberg ML. PMID: 28187996.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    19. Changes in Imaging and Cognition in Juvenile Rats After Whole-Brain Irradiation. Int J Radiat Oncol Biol Phys. 2016 10 01; 96(2):470-478. Brown RJ, Jun BJ, Cushman JD, Nguyen C, Beighley AH, Blanchard J, Iwamoto K, Schaue D, Harris NG, Jentsch JD, Bluml S, McBride WH. PMID: 27478168; PMCID: PMC5563160.
      View in: PubMed   Mentions: 2     Fields:    Translation:Animals
    20. Investigation of DNA Damage Dose-Response Kinetics after Ionizing Radiation Schemes Similar to CT Protocols. Radiat Res. 2015 Jun; 183(6):701-7. Elgart SR, Bostani M, Mok KC, Adibi A, Ruehm S, Enzmann D, McNitt-Gray M, Iwamoto KS. PMID: 25950819.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimalsCells
    21. Tumor control probability and the utility of 4D vs 3D dose calculations for stereotactic body radiotherapy for lung cancer. Med Dosim. 2015; 40(1):64-9. Valdes G, Robinson C, Lee P, Morel D, Low D, Iwamoto KS, Lamb JM. PMID: 25542785.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    22. Enrichment rescues contextual discrimination deficit associated with immediate shock. Hippocampus. 2015 Mar; 25(3):385-92. Clemenson GD, Lee SW, Deng W, Barrera VR, Iwamoto KS, Fanselow MS, Gage FH. PMID: 25330953; PMCID: PMC4398310.
      View in: PubMed   Mentions: 22     Fields:    Translation:AnimalsCells
    23. Radiosensitization of gliomas by intracellular generation of 5-fluorouracil potentiates prodrug activator gene therapy with a retroviral replicating vector. Cancer Gene Ther. 2014 Oct; 21(10):405-410. Takahashi M, Valdes G, Hiraoka K, Inagaki A, Kamijima S, Micewicz E, Gruber HE, Robbins JM, Jolly DJ, McBride WH, Iwamoto KS, Kasahara N. PMID: 25301172; PMCID: PMC4246057.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansAnimalsCells
    24. The high-affinity maltose switch MBP317-347 has low affinity for glucose: implications for targeting tumors with metabolically directed enzyme prodrug therapy. Chem Biol Drug Des. 2014 Mar; 83(3):266-71. Valdes G, Schulte RW, Ostermeier M, Iwamoto KS. PMID: 24131788.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    25. Factors affecting tumor (18) F-FDG uptake in longitudinal mouse PET studies. EJNMMI Res. 2013; 3:51. Sha W, Ye H, Iwamoto KS, Wong KP, Wilks MQ, Stout D, McBride W, Huang SC. PMID: 23841937; PMCID: PMC3718724.
      View in: PubMed   Mentions: 7  
    26. Re-evaluation of cellular radiosensitization by 5-fluorouracil: high-dose, pulsed administration is effective and preferable to conventional low-dose, chronic administration. Int J Radiat Biol. 2013 Oct; 89(10):851-62. Valdes G, Iwamoto KS. PMID: 23607451.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCells
    27. Young dentate granule cells mediate pattern separation, whereas old granule cells facilitate pattern completion. Cell. 2012 Mar 30; 149(1):188-201. Nakashiba T, Cushman JD, Pelkey KA, Renaudineau S, Buhl DL, McHugh TJ, Rodriguez Barrera V, Chittajallu R, Iwamoto KS, McBain CJ, Fanselow MS, Tonegawa S. PMID: 22365813; PMCID: PMC3319279.
      View in: PubMed   Mentions: 374     Fields:    Translation:Animals
    28. Cellular autofluorescence following ionizing radiation. PLoS One. 2012; 7(2):e32062. Schaue D, Ratikan JA, Iwamoto KS. PMID: 22384140; PMCID: PMC3284545.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansAnimalsCells
    29. Maximizing tumor immunity with fractionated radiation. Int J Radiat Oncol Biol Phys. 2012 Jul 15; 83(4):1306-10. Schaue D, Ratikan JA, Iwamoto KS, McBride WH. PMID: 22208977; PMCID: PMC3337972.
      View in: PubMed   Mentions: 227     Fields:    Translation:AnimalsCells
    30. Radiation enhances regulatory T cell representation. Int J Radiat Oncol Biol Phys. 2011 Nov 15; 81(4):1128-35. Kachikwu EL, Iwamoto KS, Liao YP, DeMarco JJ, Agazaryan N, Economou JS, McBride WH, Schaue D. PMID: 21093169; PMCID: PMC3117954.
      View in: PubMed   Mentions: 156     Fields:    Translation:AnimalsCells
    31. High-throughput screening identifies two classes of antibiotics as radioprotectors: tetracyclines and fluoroquinolones. Clin Cancer Res. 2009 Dec 01; 15(23):7238-45. Kim K, Pollard JM, Norris AJ, McDonald JT, Sun Y, Micewicz E, Pettijohn K, Damoiseaux R, Iwamoto KS, Sayre JW, Price BD, Gatti RA, McBride WH. PMID: 19920105; PMCID: PMC2787903.
      View in: PubMed   Mentions: 25     Fields:    Translation:HumansAnimalsCells
    32. Imaging of radiation effects on cellular 26S proteasome function in situ. Int J Radiat Biol. 2009 Jun; 85(6):483-94. Brush JM, Kim K, Sayre JW, McBride WH, Iwamoto KS. PMID: 19401903; PMCID: PMC2775098.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    33. Local irradiation of murine melanoma affects the development of tumour-specific immunity. Immunology. 2009 Sep; 128(1 Suppl):e797-804. Liao YP, Wang CC, Schaue D, Iwamoto KS, McBride WH. PMID: 19740341; PMCID: PMC2753951.
      View in: PubMed   Mentions: 8     Fields:    Translation:AnimalsCells
    34. Refinement of the dichlorofluorescein assay for flow cytometric measurement of reactive oxygen species in irradiated and bystander cell populations. Radiat Res. 2008 Apr; 169(4):460-8. Hafer K, Iwamoto KS, Schiestl RH. PMID: 18363435.
      View in: PubMed   Mentions: 27     Fields:    Translation:AnimalsCells
    35. Epidermal growth factor receptor vIII expression in U87 glioblastoma cells alters their proteasome composition, function, and response to irradiation. Mol Cancer Res. 2008 Mar; 6(3):426-34. Kim K, Brush JM, Watson PA, Cacalano NA, Iwamoto KS, McBride WH. PMID: 18337449; PMCID: PMC2877368.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansCells
    36. Antiproton radiotherapy. Radiother Oncol. 2008 Jan; 86(1):14-9. Bassler N, Alsner J, Beyer G, DeMarco JJ, Doser M, Hajdukovic D, Hartley O, Iwamoto KS, Jäkel O, Knudsen HV, Kovacevic S, Møller SP, Overgaard J, Petersen JB, Solberg TD, Sørensen BS, Vranjes S, Wouters BG, Holzscheiter MH. PMID: 18158194.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimalsCells
    37. Adaptive response to gamma radiation in mammalian cells proficient and deficient in components of nucleotide excision repair. Radiat Res. 2007 Aug; 168(2):168-74. Hafer K, Iwamoto KS, Iwamoto KK, Scuric Z, Schiestl RH. PMID: 17638404.
      View in: PubMed   Mentions: 11     Fields:    Translation:AnimalsCells
    38. Radiation-induced posttranscriptional control of M6P/IGF2r expression in breast cancer cell lines. Mol Carcinog. 2007 Jul; 46(7):497-502. Iwamoto KS, Barber CL. PMID: 17295243.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    39. A dose-dependent decrease in the fraction of cases harboring M6P/IGF2R mutations in hepatocellular carcinomas from the atomic bomb survivors. Radiat Res. 2006 Dec; 166(6):870-6. Iwamoto KS, Yano S, Barber CL, MacPhee DG, Tokuoka S. PMID: 17149973.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansPHPublic Health
    40. The biological effectiveness of antiproton irradiation. Radiother Oncol. 2006 Dec; 81(3):233-42. Holzscheiter MH, Bassler N, Agazaryan N, Beyer G, Blackmore E, DeMarco JJ, Doser M, Durand RE, Hartley O, Iwamoto KS, Knudsen HV, Landua R, Maggiore C, McBride WH, Møller SP, Petersen J, Skarsgard LD, Smathers JB, Solberg TD, Uggerhøj UI, Vranjes S, Withers HR, Wong M, Wouters BG. PMID: 17069916.
      View in: PubMed   Mentions: 7     Fields:    Translation:AnimalsCells
    41. HDJ-2 as a target for radiosensitization of glioblastoma multiforme cells by the farnesyltransferase inhibitor R115777 and the role of the p53/p21 pathway. Cancer Res. 2006 Jul 01; 66(13):6756-62. Wang CC, Liao YP, Mischel PS, Iwamoto KS, Cacalano NA, McBride WH. PMID: 16818651.
      View in: PubMed   Mentions: 23     Fields:    Translation:HumansCells
    42. Molecular basis of basal cell carcinogenesis in the atomic-bomb survivor population: p53 and PTCH gene alterations. Carcinogenesis. 2006 Nov; 27(11):2286-94. Mizuno T, Tokuoka S, Kishikawa M, Nakashima E, Mabuchi K, Iwamoto KS. PMID: 16777989.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    43. Point-source irradiation with eccentric rotation causes inhomogeneous dose distribution. Radiat Res. 2006 May; 165(5):616-20. Hafer K, Scuric Z, Iwamoto KS, Schiestl RH. PMID: 16669744.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    44. Proteasome structures affected by ionizing radiation. Mol Cancer Res. 2005 Jul; 3(7):381-90. Pervan M, Iwamoto KS, McBride WH. PMID: 16046549.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansCells
    45. Ionizing radiation affects human MART-1 melanoma antigen processing and presentation by dendritic cells. J Immunol. 2004 Aug 15; 173(4):2462-9. Liao YP, Wang CC, Butterfield LH, Economou JS, Ribas A, Meng WS, Iwamoto KS, McBride WH. PMID: 15294960.
      View in: PubMed   Mentions: 50     Fields:    Translation:HumansAnimalsCells
    46. A sense of danger from radiation. Radiat Res. 2004 Jul; 162(1):1-19. McBride WH, Chiang CS, Olson JL, Wang CC, Hong JH, Pajonk F, Dougherty GJ, Iwamoto KS, Pervan M, Liao YP. PMID: 15222781.
      View in: PubMed   Mentions: 129     Fields:    Translation:HumansAnimalsPHPublic Health
    47. The role of the ubiquitin/proteasome system in cellular responses to radiation. Oncogene. 2003 Sep 01; 22(37):5755-73. McBride WH, Iwamoto KS, Syljuasen R, Pervan M, Pajonk F. PMID: 12947384.
      View in: PubMed   Mentions: 35     Fields:    Translation:HumansAnimals
    48. Tracking the errant cell after the atomic bombings: what went wrong? Health Phys. 2003 Jul; 85(1):81-3. Iwamoto KS. PMID: 12852474.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    49. Induction of radioprotective peroxiredoxin-I by ionizing irradiation. J Neurosci Res. 2002 Dec 15; 70(6):794-8. Chen WC, McBride WH, Iwamoto KS, Barber CL, Wang CC, Oh YT, Liao YP, Hong JH, de Vellis J, Shau H. PMID: 12444601.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansAnimalsCells
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