-
HJV mutations causing hemochromatosis: variable phenotypic expression in a pair of twins. Haematologica. 2024 08 01; 109(8):2741-2744.
Vadivelan A, Zhang S, Srole DN, Marcus EA, Neto GC, Nemeth E, Ganz T, De Oliveira S. PMID: 38450514; PMCID: PMC11290577.
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PubMed Mentions: Fields:
Translation:
Humans
-
Maternal prolactin or estrogen signaling in hepatocytes does not regulate iron homeostasis during pregnancy. Haematologica. 2024 Aug 01.
Zhang V, Fisher AL, Hewitt MS, Ganz T, Nemeth E, Sangkhae V. PMID: 39086305.
View in:
PubMed Mentions: Fields:
-
N-Myristoytransferase Inhibition Causes Mitochondrial Iron Overload and Parthanatos in TIM17A-Dependent Aggressive Lung Carcinoma. Cancer Res Commun. 2024 Jul 01; 4(7):1815-1833.
Geroyska S, Mejia I, Chan AA, Navarrete M, Pandey V, Kharpatin S, Noguti J, Wang F, Srole D, Chou TF, Wohlschlegel J, Nemeth E, Damoiseaux R, Shackelford DB, Lee DJ, Díaz B. PMID: 38949950; PMCID: PMC11270646.
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PubMed Mentions: Fields:
Translation:
HumansAnimalsCells
-
Targeting PKCα alleviates iron overload in diabetes and hemochromatosis through the inhibition of ferroportin Blood. 2024 06 11.
Banerjee S, Lu S, Jain A, Wang I, Tao H, Srinivasan S, Nemeth E, He P. PMID: 38861671.
View in:
PubMed Mentions:
1 Fields:
Translation:
HumansAnimalsCells
-
Multiple Infections, Nutrient Deficiencies, and Inflammation as Determinants of Anemia and Iron Status during Pregnancy: The MINDI Cohort. Nutrients. 2024 Jun 02; 16(11).
González-Fernández D, Nemeth E, Pons EDC, Rueda D, Sinisterra OT, Murillo E, Sangkhae V, Starr L, Scott ME, Koski KG. PMID: 38892681; PMCID: PMC11174717.
View in:
PubMed Mentions: Fields:
Translation:
Humans
-
View in:
PubMed Mentions: Fields:
Translation:
Humans
-
The hepatokine FGL1 regulates hepcidin and iron metabolism during anemia in mice by antagonizing BMP signaling. Blood. 2024 Mar 28; 143(13):1282-1292.
Sardo U, Perrier P, Cormier K, Sotin M, Personnaz J, Medjbeur T, Desquesnes A, Cannizzo L, Ruiz-Martinez M, Thevenin J, Billoré B, Jung G, Abboud E, Peyssonnaux C, Nemeth E, Ginzburg YZ, Ganz T, Kautz L. PMID: 38232308; PMCID: PMC11103088.
View in:
PubMed Mentions:
2 Fields:
Translation:
Animals
-
Anemia in Pregnancy With CKD. Kidney Int Rep. 2024 May; 9(5):1183-1197.
de Jong MFC, Nemeth E, Rawee P, Bramham K, Eisenga MF. PMID: 38707831; PMCID: PMC11069017.
View in:
PubMed Mentions:
-
Targeting PKC alleviates iron overload in diabetes and hemochromatosis. bioRxiv. 2023 Nov 29.
Banerjee S, Lu S, Jain A, Wang I, Tao H, Srinivasan S, Nemeth E, He P. PMID: 38076948; PMCID: PMC10705472.
View in:
PubMed Mentions:
-
Placental ferroportin protein abundance is associated with neonatal erythropoietic activity and iron status in newborns at high risk for iron deficiency and anemia. Am J Clin Nutr. 2024 01; 119(1):76-86.
Barad A, Guillet R, Pressman EK, Katzman PJ, Ganz T, Nemeth E, O'Brien KO. PMID: 37890671; PMCID: PMC10808842.
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PubMed Mentions: Fields:
Translation:
HumansAnimals
-
Characterization of erythroferrone structural domains relevant to its iron-regulatory function. J Biol Chem. 2023 Dec; 299(12):105374.
Srole DN, Jung G, Waring AJ, Nemeth E, Ganz T. PMID: 37866631; PMCID: PMC10692919.
View in:
PubMed Mentions:
2 Fields:
Translation:
HumansCells
-
The complex relationship between iron status and anemia in pregnant and postpartum women in India: Analysis of two Indian study cohorts of uncomplicated pregnancies. Am J Hematol. 2023 11; 98(11):1721-1731.
Nair M, Choudhury SS, Rani A, Solomi C, Kakoty SD, Medhi R, Rao S, Mahanta P, Zahir F, Roy I, Chhabra S, Deka G, Minz B, Deka R, Opondo C, Churchill D, Lakhal-Littleton S, Nemeth E, MaatHRI collaboration. PMID: 37651649; PMCID: PMC11441206.
View in:
PubMed Mentions:
3 Fields:
Translation:
Humans
-
Erythroferrone exacerbates iron overload and ineffective extramedullary erythropoiesis in a mouse model of β-thalassemia. Blood Adv. 2023 07 25; 7(14):3339-3349.
Olivera J, Zhang V, Nemeth E, Ganz T. PMID: 36995275; PMCID: PMC10345853.
View in:
PubMed Mentions:
3 Fields:
Translation:
HumansAnimals
-
Fetal factors disrupt placental and maternal iron homeostasis in murine β-thalassemia. Blood. 2023 07 13; 142(2):185-196.
Yu Y, Woloshun RR, Lee JK, Ebea PO, Zhu S, Nemeth E, Garrick LM, Garrick MD, Collins JF. PMID: 37146247; PMCID: PMC10352602.
View in:
PubMed Mentions:
2 Fields:
Translation:
HumansAnimals
-
Hypoferremia of inflammation: Innate host defense against infections. Blood Cells Mol Dis. 2024 01; 104:102777.
Ganz T, Nemeth E. PMID: 37391347.
View in:
PubMed Mentions:
3 Fields:
Translation:
Animals
-
Iron Homeostasis During Pregnancy: Maternal, Placental, and Fetal Regulatory Mechanisms. Annu Rev Nutr. 2023 08 21; 43:279-300.
Sangkhae V, Fisher AL, Ganz T, Nemeth E. PMID: 37253681; PMCID: PMC10723031.
View in:
PubMed Mentions:
9 Fields:
Translation:
HumansAnimals
-
Placental Erythroferrone and Erythropoietin mRNA Expression is not Associated with Maternal or Neonatal Iron Status in Adolescents Carrying Singletons and Adult Women Carrying Multiples. J Nutr. 2023 07; 153(7):1950-1958.
Delaney KM, Barad A, Castillo LF, Hasund CM, Guillet R, Pressman EK, Katzman PJ, Ganz T, Nemeth E, O'Brien KO. PMID: 37253412; PMCID: PMC10375499.
View in:
PubMed Mentions:
2 Fields:
Translation:
Humans
-
Iron is a modifier of the phenotypes of JAK2-mutant myeloproliferative neoplasms. Blood. 2023 04 27; 141(17):2127-2140.
Stetka J, Usart M, Kubovcakova L, Rai S, Rao TN, Sutter J, Hao-Shen H, Dirnhofer S, Geier F, Bader MS, Passweg JR, Manolova V, Dürrenberger F, Ahmed N, Schroeder T, Ganz T, Nemeth E, Silvestri L, Nai A, Camaschella C, Skoda RC. PMID: 36758212.
View in:
PubMed Mentions:
4 Fields:
Translation:
Animals
-
A mouse model characterizes the roles of ZIP8 in systemic iron recycling and lung inflammation and infection. Blood Adv. 2023 04 11; 7(7):1336-1349.
Zhang V, Jenkitkasemwong S, Liu Q, Ganz T, Nemeth E, Knutson MD, Kim A. PMID: 36260707; PMCID: PMC10119600.
View in:
PubMed Mentions:
5 Fields:
Translation:
Animals
-
The hepatokine FGL1 regulates hepcidin and iron metabolism during the recovery from hemorrhage-induced anemia in mice. bioRxiv. 2023 Apr 06.
Sardo U, Perrier P, Cormier K, Sotin M, Desquesnes A, Cannizzo L, Ruiz-Martinez M, Thevenin J, Billoré B, Jung G, Abboud E, Peyssonnaux C, Nemeth E, Ginzburg YZ, Ganz T, Kautz L. PMID: 37066218; PMCID: PMC10104156.
View in:
PubMed Mentions:
-
Pathogenic Mechanisms in Thalassemia II: Iron Overload. Hematol Oncol Clin North Am. 2023 04; 37(2):353-363.
Ganz T, Nemeth E. PMID: 36907608.
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PubMed Mentions: Fields:
Translation:
Humans
-
Comparative analysis of the functional properties of human and mouse ferroportin. Am J Physiol Cell Physiol. 2023 05 01; 324(5):C1110-C1118.
Azucenas CR, Ruwe TA, Bonamer JP, Qiao B, Ganz T, Jormakka M, Nemeth E, Mackenzie B. PMID: 36939203; PMCID: PMC10191125.
View in:
PubMed Mentions:
2 Fields:
Translation:
HumansAnimalsCells
-
TMPRSS6 as a Therapeutic Target for Disorders of Erythropoiesis and Iron Homeostasis. Adv Ther. 2023 04; 40(4):1317-1333.
Ganz T, Nemeth E, Rivella S, Goldberg P, Dibble AR, McCaleb ML, Guo S, Monia BP, Barrett TD. PMID: 36690839; PMCID: PMC10070284.
View in:
PubMed Mentions:
6 Fields:
Translation:
HumansAnimals
-
Bmpr2 mutant mice are an inadequate model for studying iron deficiency in pulmonary hypertension. Pulm Circ. 2022 Oct; 12(4):e12151.
Zhang V, Ganz T, Nemeth E, Umar S, Kim A. PMID: 36568690; PMCID: PMC9768458.
View in:
PubMed Mentions:
2
-
Multiple Indicators of Undernutrition, Infection, and Inflammation in Lactating Women Are Associated with Maternal Iron Status and Infant Anthropometry in Panama: The MINDI Cohort. Nutrients. 2022 Aug 25; 14(17).
González-Fernández D, Nemeth E, Pons EDC, Sinisterra OT, Rueda D, Starr L, Sangkhae V, Murillo E, Scott ME, Koski KG. PMID: 36079755; PMCID: PMC9460351.
View in:
PubMed Mentions:
7 Fields:
Translation:
Humans
-
Erythroferrone contributes to iron mobilization for embryo erythropoiesis in iron-deficient mouse pregnancies. Am J Hematol. 2022 10; 97(10):1348-1358.
Sangkhae V, Yu V, Coffey R, O'Brien KO, Ganz T, Nemeth E. PMID: 36071577; PMCID: PMC9462668.
View in:
PubMed Mentions:
4 Fields:
Translation:
Animals
-
Hepcidin and Iron in Health and Disease. Annu Rev Med. 2023 01 27; 74:261-277.
Nemeth E, Ganz T. PMID: 35905974; PMCID: PMC9943683.
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PubMed Mentions:
66 Fields:
Translation:
Humans
-
Quantitating Iron Transport across the Mouse Placenta In Vivo using Nonradioactive Iron Isotopes. J Vis Exp. 2022 05 10; (183).
Sangkhae V, Nemeth E. PMID: 35635455; PMCID: PMC9927870.
View in:
PubMed Mentions:
2 Fields:
Translation:
Animals
-
Hepcidin and Erythroferrone Complement the Athlete Biological Passport in the Detection of Autologous Blood Transfusion. Med Sci Sports Exerc. 2022 09 01; 54(9):1604-1616.
Breenfeldt Andersen A, Bejder J, Bonne TC, Sørensen H, Sørensen H, Jung G, Ganz T, Nemeth E, Secher NH, Johansson PI, Nordsborg NB. PMID: 35482790.
View in:
PubMed Mentions:
5 Fields:
Translation:
HumansCells
-
Human defensin-inspired discovery of peptidomimetic antibiotics. Proc Natl Acad Sci U S A. 2022 03 08; 119(10):e2117283119.
Luo G, Zhang J, Wang H, Sun Y, Cheng B, Xu Z, Zhang Y, Li H, Lu W, Nemeth E, Ganz T, Fang X. PMID: 35238683; PMCID: PMC8916014.
View in:
PubMed Mentions:
7 Fields:
Translation:
HumansCells
-
Hepcidin is elevated in primary and secondary myelofibrosis and remains elevated in patients treated with ruxolitinib. Br J Haematol. 2022 05; 197(4):e49-e52.
Zhou A, Kong T, Fowles JS, Jung CL, Allen MJ, Fisher DAC, Fulbright M, Nemeth E, Ganz T, Oh ST. PMID: 35128632; PMCID: PMC11223714.
View in:
PubMed Mentions:
10 Fields:
Translation:
Humans
-
Erythroid overproduction of erythroferrone causes iron overload and developmental abnormalities in mice. Blood. 2022 01 20; 139(3):439-451.
Coffey R, Jung G, Olivera JD, Karin G, Pereira RC, Nemeth E, Ganz T. PMID: 34614145; PMCID: PMC8777203.
View in:
PubMed Mentions:
16 Fields:
Translation:
AnimalsCells
-
Enteral ferric citrate absorption is dependent on the iron transport protein ferroportin. Kidney Int. 2022 04; 101(4):711-719.
Hanudel MR, Czaya B, Wong S, Rappaport M, Namjoshi S, Chua K, Jung G, Gabayan V, Qiao B, Nemeth E, Ganz T. PMID: 34838540; PMCID: PMC8940695.
View in:
PubMed Mentions:
6 Fields:
Translation:
HumansAnimals
-
Umbilical Cord Erythroferrone Is Inversely Associated with Hepcidin, but Does Not Capture the Most Variability in Iron Status of Neonates Born to Teens Carrying Singletons and Women Carrying Multiples. J Nutr. 2021 09 04; 151(9):2590-2600.
Delaney KM, Guillet R, Pressman EK, Ganz T, Nemeth E, O'Brien KO. PMID: 34236433; PMCID: PMC8417932.
View in:
PubMed Mentions:
6 Fields:
Translation:
Humans
-
Prepregnancy Obesity Does Not Impact Placental Iron Trafficking. J Nutr. 2021 09 04; 151(9):2646-2654.
Tussing-Humphreys L, LaBomascus B, O'Brien K, Nemeth E, Sangkhae V, Steffen AD, Castellanos K, DeMartelly V, Ruchob R, Welke L, Hemphill NO, Pezley L, McLeod A, Hirsch B, Elam G, Ferrans CE, Koenig MD. PMID: 34132349; PMCID: PMC8417928.
View in:
PubMed Mentions:
5 Fields:
Translation:
Humans
-
Iron loading induces cholesterol synthesis and sensitizes endothelial cells to TNFα-mediated apoptosis. J Biol Chem. 2021 10; 297(4):101156.
Fisher AL, Srole DN, Palaskas NJ, Meriwether D, Reddy ST, Ganz T, Nemeth E. PMID: 34480898; PMCID: PMC8463868.
View in:
PubMed Mentions:
8 Fields:
Translation:
HumansCells
-
Vaccine efficacy and iron deficiency: an intertwined pair? Lancet Haematol. 2021 Sep; 8(9):e666-e669.
Drakesmith H, Pasricha SR, Cabantchik I, Hershko C, Weiss G, Girelli D, Stoffel N, Muckenthaler MU, Nemeth E, Camaschella C, Klenerman P, Zimmermann MB. PMID: 34450104; PMCID: PMC8384343.
View in:
PubMed Mentions:
23 Fields:
Translation:
HumansCellsPHPublic Health
-
Serum Erythroferrone During Pregnancy Is Related to Erythropoietin but Does Not Predict the Risk of Anemia. J Nutr. 2021 07 01; 151(7):1824-1833.
Delaney KM, Guillet R, Pressman EK, Ganz T, Nemeth E, O'Brien KO. PMID: 33982118; PMCID: PMC8245876.
View in:
PubMed Mentions:
6 Fields:
Translation:
Humans
-
Iron-dependent apoptosis causes embryotoxicity in inflamed and obese pregnancy. Nat Commun. 2021 06 29; 12(1):4026.
Fisher AL, Sangkhae V, Balušíková K, Palaskas NJ, Ganz T, Nemeth E. PMID: 34188052; PMCID: PMC8242011.
View in:
PubMed Mentions:
11 Fields:
Translation:
HumansAnimalsCells
-
Effects of altitude and recombinant human erythropoietin on iron metabolism: a randomized controlled trial. Am J Physiol Regul Integr Comp Physiol. 2021 08 01; 321(2):R152-R161.
Breenfeldt Andersen A, Bonne TC, Bejder J, Jung G, Ganz T, Nemeth E, Olsen NV, Huertas JR, Nordsborg NB. PMID: 34160288; PMCID: PMC8887998.
View in:
PubMed Mentions:
3 Fields:
Translation:
Humans
-
Hepcidin-Ferroportin Interaction Controls Systemic Iron Homeostasis. Int J Mol Sci. 2021 Jun 17; 22(12).
Nemeth E, Ganz T. PMID: 34204327; PMCID: PMC8235187.
View in:
PubMed Mentions:
135 Fields:
Translation:
HumansAnimalsCells
-
The hepcidin regulator erythroferrone is a new member of the erythropoiesis-iron-bone circuitry. Elife. 2021 05 18; 10.
Castro-Mollo M, Gera S, Ruiz-Martinez M, Feola M, Gumerova A, Planoutene M, Clementelli C, Sangkhae V, Casu C, Kim SM, Ostland V, Han H, Nemeth E, Fleming R, Rivella S, Lizneva D, Yuen T, Zaidi M, Ginzburg Y. PMID: 34002695; PMCID: PMC8205482.
View in:
PubMed Mentions:
6 Fields:
Translation:
AnimalsCells
-
INTERGROWTH-21 Identifies High Prevalence of Low Symphysis-Fundal Height in Indigenous Pregnant Women Experiencing Multiple Infections, Nutrient Deficiencies, and Inflammation: The Maternal Infections, Nutrient Deficiencies, and Inflammation (MINDI) Cohort. Curr Dev Nutr. 2021 Apr; 5(4):nzab012.
González-Fernández D, Nemeth E, Pons EDC, Rueda D, Sinisterra OT, Murillo E, Sangkhae V, Starr LM, Scott ME, Koski KG. PMID: 33898918; PMCID: PMC8053398.
View in:
PubMed Mentions:
5
-
Pursuing Orally Bioavailable Hepcidin Analogues via Cyclic N-Methylated Mini-Hepcidins. Biomedicines. 2021 Feb 08; 9(2).
Goncalves Monteiro D, van Dijk JWA, Aliyanto R, Fung E, Nemeth E, Ganz T, Rosengren J, Clark RJ. PMID: 33567510; PMCID: PMC7915682.
View in:
PubMed Mentions:
2
-
Isolation and thermal stabilization of mouse ferroportin. FEBS Open Bio. 2021 01; 11(1):26-34.
Deshpande CN, Azucenas CR, Qiao B, Nomura N, Xin V, Font J, Iwata S, Ganz T, Nemeth E, Mackenzie B, Jormakka M. PMID: 33190422; PMCID: PMC7780100.
View in:
PubMed Mentions: Fields:
Translation:
Animals
-
Maternal hepcidin determines embryo iron homeostasis in mice. Blood. 2020 11 05; 136(19):2206-2216.
Sangkhae V, Fisher AL, Chua KJ, Ruchala P, Ganz T, Nemeth E. PMID: 32584957; PMCID: PMC7645983.
View in:
PubMed Mentions:
23 Fields:
Translation:
HumansAnimals
-
Lung Iron Overload Does Not Exacerbate the Fibrotic Response to Bleomycin in a Mouse Model of Pulmonary Fibrosis. Am J Respir Cell Mol Biol. 2020 11; 63(5):713-716.
Zhang V, Nemeth E, Kim A. PMID: 33124901; PMCID: PMC7605158.
View in:
PubMed Mentions:
1 Fields:
Translation:
Animals
-
Prognostic associations of plasma hepcidin in women with early breast cancer. Breast Cancer Res Treat. 2020 Dec; 184(3):927-935.
Jerzak KJ, Lohmann AE, Ennis M, Nemeth E, Ganz T, Goodwin PJ. PMID: 32960376; PMCID: PMC7883934.
View in:
PubMed Mentions:
4 Fields:
Translation:
Humans
-
Clinical Immunoassay for Human Hepcidin Predicts Iron Deficiency in First-Time Blood Donors. J Appl Lab Med. 2020 09 01; 5(5):943-953.
Gutschow P, Han H, Olbina G, Westerman K, Nemeth E, Ganz T, Copeland K, Westerman M, Ostland V. PMID: 32674118; PMCID: PMC7497288.
View in:
PubMed Mentions:
3 Fields:
Translation:
Humans
-
Iron overload causes a mild and transient increase in acute lung injury. Physiol Rep. 2020 06; 8(12):e14470.
Zhang V, Ganz T, Nemeth E, Kim A. PMID: 32596989; PMCID: PMC7322498.
View in:
PubMed Mentions:
7 Fields:
Translation:
Animals
-
Author Correction: Identification of erythroferrone as an erythroid regulator of iron metabolism. Nat Genet. 2020 Apr; 52(4):463.
Kautz L, Jung G, Valore EV, Rivella S, Nemeth E, Ganz T. PMID: 32107478.
View in:
PubMed Mentions:
2 Fields:
-
Fetal and amniotic fluid iron homeostasis in healthy and complicated murine, macaque, and human pregnancy. JCI Insight. 2020 02 27; 5(4).
Fisher AL, Sangkhae V, Presicce P, Chougnet CA, Jobe AH, Kallapur SG, Tabbah S, Buhimschi CS, Buhimschi IA, Ganz T, Nemeth E. PMID: 31990688; PMCID: PMC7101151.
View in:
PubMed Mentions:
16 Fields:
Translation:
HumansAnimals
-
Regulation of iron homeostasis through the erythroferrone-hepcidin axis in sickle cell disease. Br J Haematol. 2020 06; 189(6):1204-1209.
Mangaonkar AA, Thawer F, Son J, Ajebo G, Xu H, Barrett NJ, Wells LG, Bowman L, Clair B, Patel N, Bora P, Jung G, Nemeth E, Kutlar A. PMID: 32030737; PMCID: PMC8011855.
View in:
PubMed Mentions:
13 Fields:
Translation:
HumansCTClinical Trials
-
Effects of maternal iron status on placental and fetal iron homeostasis. J Clin Invest. 2020 02 03; 130(2):625-640.
Sangkhae V, Fisher AL, Wong S, Koenig MD, Tussing-Humphreys L, Chu A, Lelic M, Ganz T, Nemeth E. PMID: 31661462; PMCID: PMC6994143.
View in:
PubMed Mentions:
74 Fields:
Translation:
HumansAnimalsCells
-
Effects of erythropoietin on fibroblast growth factor 23 in mice and humans. Nephrol Dial Transplant. 2019 12 01; 34(12):2057-2065.
Hanudel MR, Eisenga MF, Rappaport M, Chua K, Qiao B, Jung G, Gabayan V, Gales B, Ramos G, de Jong MA, van Zanden JJ, de Borst MH, Bakker SJL, Nemeth E, Salusky IB, Gaillard CAJM, Ganz T. PMID: 30007314; PMCID: PMC6888066.
View in:
PubMed Mentions:
55 Fields:
Translation:
HumansAnimals
-
A variant erythroferrone disrupts iron homeostasis in SF3B1-mutated myelodysplastic syndrome. Sci Transl Med. 2019 07 10; 11(500).
Bondu S, Alary AS, Lefèvre C, Houy A, Jung G, Lefebvre T, Rombaut D, Boussaid I, Bousta A, Guillonneau F, Perrier P, Alsafadi S, Wassef M, Margueron R, Rousseau A, Droin N, Cagnard N, Kaltenbach S, Winter S, Kubasch AS, Bouscary D, Santini V, Toma A, Hunault M, Stamatoullas A, Gyan E, Cluzeau T, Platzbecker U, Adès L, Puy H, Stern MH, Karim Z, Mayeux P, Nemeth E, Park S, Ganz T, Kautz L, Kosmider O, Fontenay M. PMID: 31292266; PMCID: PMC8005358.
-
To induce or not to induce: the fight over hepcidin regulation. Haematologica. 2019 06; 104(6):1093-1095.
Sangkhae V, Nemeth E. PMID: 31152085; PMCID: PMC6545853.
View in:
PubMed Mentions:
4 Fields:
Translation:
Humans
-
Single versus Split Dose of Iron Optimizes Hemoglobin Mass Gains at 2106 m Altitude. Med Sci Sports Exerc. 2019 04; 51(4):751-759.
Hall R, Peeling P, Nemeth E, Bergland D, McCluskey WTP, Stellingwerff T. PMID: 30882751; PMCID: PMC8882001.
View in:
PubMed Mentions:
13 Fields:
Translation:
Humans
-
Umbilical Cord Serum Ferritin Concentration is Inversely Associated with Umbilical Cord Hemoglobin in Neonates Born to Adolescents Carrying Singletons and Women Carrying Multiples. J Nutr. 2019 03 01; 149(3):406-415.
Delaney KM, Guillet R, Fleming RE, Ru Y, Pressman EK, Vermeylen F, Nemeth E, O'Brien KO. PMID: 30770543; PMCID: PMC6398393.
View in:
PubMed Mentions:
10 Fields:
Translation:
Humans
-
Iron in Lung Pathology. Pharmaceuticals (Basel). 2019 Feb 15; 12(1).
Zhang V, Nemeth E, Kim A. PMID: 30781366; PMCID: PMC6469192.
View in:
PubMed Mentions:
22
-
The Aftermath of Surviving Acute Radiation Hematopoietic Syndrome and its Mitigation. Radiat Res. 2019 04; 191(4):323-334.
Micewicz ED, Iwamoto KS, Ratikan JA, Nguyen C, Xie MW, Cheng G, Boxx GM, Deriu E, Damoiseaux RD, Whitelegge JP, Ruchala PP, Avetisyan R, Jung ME, Lawson G, Nemeth E, Ganz T, Sayre JW, McBride WH, Schaue D. PMID: 30730284; PMCID: PMC6482953.
View in:
PubMed Mentions:
13 Fields:
Translation:
AnimalsPHPublic Health
-
Increased gene copy number of DEFA1/DEFA3 worsens sepsis by inducing endothelial pyroptosis. Proc Natl Acad Sci U S A. 2019 02 19; 116(8):3161-3170.
Chen Q, Yang Y, Hou J, Shu Q, Yin Y, Fu W, Han F, Hou T, Zeng C, Nemeth E, Linzmeier R, Ganz T, Fang X. PMID: 30718392; PMCID: PMC6386704.
View in:
PubMed Mentions:
31 Fields:
Translation:
HumansAnimalsCells
-
Hepatic hepcidin/intestinal HIF-2α axis maintains iron absorption during iron deficiency and overload. J Clin Invest. 2019 01 02; 129(1):336-348.
Schwartz AJ, Das NK, Ramakrishnan SK, Jain C, Jurkovic MT, Wu J, Nemeth E, Lakhal-Littleton S, Colacino JA, Shah YM. PMID: 30352047; PMCID: PMC6307944.
View in:
PubMed Mentions:
79 Fields:
Translation:
HumansAnimalsCells
-
Iron homeostasis in pregnancy and spontaneous abortion. Am J Hematol. 2019 02; 94(2):184-188.
Guo Y, Zhang N, Zhang D, Ren Q, Ganz T, Liu S, Nemeth E. PMID: 30394565; PMCID: PMC6687303.
View in:
PubMed Mentions:
13 Fields:
Translation:
Humans
-
Mechanisms responsible for reduced erythropoiesis during androgen deprivation therapy in men with prostate cancer. Am J Physiol Endocrinol Metab. 2018 12 01; 315(6):E1185-E1193.
Gagliano-Jucá T, Pencina KM, Ganz T, Travison TG, Kantoff PW, Nguyen PL, Taplin ME, Kibel AS, Li Z, Huang G, Edwards RR, Nemeth E, Basaria S. PMID: 30325657; PMCID: PMC6336960.
View in:
PubMed Mentions:
10 Fields:
Translation:
Humans
-
Erythroferrone is not required for the glucoregulatory and hematologic effects of chronic erythropoietin treatment in mice. Physiol Rep. 2018 09; 6(19):e13890.
Coffey R, Sardo U, Kautz L, Gabayan V, Nemeth E, Ganz T. PMID: 30315639; PMCID: PMC6185995.
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PubMed Mentions:
18 Fields:
Translation:
Animals
-
Calcium is an essential cofactor for metal efflux by the ferroportin transporter family. Nat Commun. 2018 08 06; 9(1):3075.
Deshpande CN, Ruwe TA, Shawki A, Xin V, Vieth KR, Valore EV, Qiao B, Ganz T, Nemeth E, Mackenzie B, Jormakka M. PMID: 30082682; PMCID: PMC6079014.
View in:
PubMed Mentions:
24 Fields:
Translation:
HumansAnimalsCells
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Intravenous Iron Does Not Augment the Hemoglobin Mass Response to Simulated Hypoxia. Med Sci Sports Exerc. 2018 08; 50(8):1669-1678.
Garvican-Lewis LA, Vuong VL, Govus AD, Peeling P, Jung G, Nemeth E, Hughes D, Lovell G, Eichner D, Gore CJ. PMID: 29538179.
View in:
PubMed Mentions:
14 Fields:
Translation:
Humans
-
Placental iron transport: The mechanism and regulatory circuits. Free Radic Biol Med. 2019 03; 133:254-261.
Sangkhae V, Nemeth E. PMID: 29981833; PMCID: PMC7059975.
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PubMed Mentions:
42 Fields:
Translation:
HumansAnimals
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Hepcidin Protects against Lethal Escherichia coli Sepsis in Mice Inoculated with Isolates from Septic Patients. Infect Immun. 2018 07; 86(7).
Stefanova D, Raychev A, Deville J, Humphries R, Campeau S, Ruchala P, Nemeth E, Ganz T, Bulut Y. PMID: 29735522; PMCID: PMC6013672.
View in:
PubMed Mentions:
27 Fields:
Translation:
HumansAnimals
-
Therapeutic recommendations in HFE hemochromatosis for p.Cys282Tyr (C282Y/C282Y) homozygous genotype. Hepatol Int. 2018 Mar; 12(2):83-86.
Adams P, Altes A, Brissot P, Butzeck B, Cabantchik I, Cançado R, Distante S, Evans P, Evans R, Ganz T, Girelli D, Hultcrantz R, McLaren G, Marris B, Milman N, Nemeth E, Nielsen P, Pineau B, Piperno A, Porto G, Prince D, Ryan J, Sanchez M, Santos P, Swinkels D, Teixeira E, Toska K, Vanclooster A, White D, Contributors and Hemochromatosis International Taskforce. PMID: 29589198; PMCID: PMC5904234.
View in:
PubMed Mentions:
24 Fields:
Translation:
Humans
-
Fetal presentation of congenital dyserythropoietic anemia type 1 with novel compound heterozygous CDAN1 mutations. Blood Cells Mol Dis. 2018 07; 71:63-66.
Meznarich JA, Draper L, Christensen RD, Yaish HM, Luem ND, Pysher TJ, Jung G, Nemeth E, Ganz T, Ward DM. PMID: 29599085; PMCID: PMC5947870.
View in:
PubMed Mentions:
4 Fields:
Translation:
Humans
-
Hepcidin agonists as therapeutic tools. Blood. 2018 04 19; 131(16):1790-1794.
Casu C, Nemeth E, Rivella S. PMID: 29523504; PMCID: PMC5909761.
View in:
PubMed Mentions:
59 Fields:
Translation:
HumansAnimals
-
Levels of the erythropoietin-responsive hormone erythroferrone in mice and humans with chronic kidney disease. Haematologica. 2018 04; 103(4):e141-e142.
Hanudel MR, Rappaport M, Chua K, Gabayan V, Qiao B, Jung G, Salusky IB, Ganz T, Nemeth E. PMID: 29419424; PMCID: PMC5865435.
View in:
PubMed Mentions:
21 Fields:
Translation:
HumansAnimals
-
Structure-function analysis of ferroportin defines the binding site and an alternative mechanism of action of hepcidin. Blood. 2018 02 22; 131(8):899-910.
Aschemeyer S, Qiao B, Stefanova D, Valore EV, Sek AC, Ruwe TA, Vieth KR, Jung G, Casu C, Rivella S, Jormakka M, Mackenzie B, Ganz T, Nemeth E. PMID: 29237594; PMCID: PMC5824336.
View in:
PubMed Mentions:
143 Fields:
Translation:
HumansAnimalsCells
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Iron homeostasis during pregnancy. Am J Clin Nutr. 2017 Dec; 106(Suppl 6):1567S-1574S.
Fisher AL, Nemeth E. PMID: 29070542; PMCID: PMC5701706.
View in:
PubMed Mentions:
130 Fields:
Translation:
HumansAnimals
-
In a Mouse Model of Sepsis, Hepcidin Ablation Ameliorates Anemia More Effectively than Iron and Erythropoietin Treatment. Shock. 2017 10; 48(4):490-497.
Khorramian E, Fung E, Chua K, Gabayan V, Ganz T, Nemeth E, Kim A. PMID: 28452907; PMCID: PMC5603371.
View in:
PubMed Mentions:
8 Fields:
Translation:
Animals
-
Erythropoietin stimulates murine and human fibroblast growth factor-23, revealing novel roles for bone and bone marrow. Haematologica. 2017 11; 102(11):e427-e430.
Clinkenbeard EL, Hanudel MR, Stayrook KR, Appaiah HN, Farrow EG, Cass TA, Summers LJ, Ip CS, Hum JM, Thomas JC, Ivan M, Richine BM, Chan RJ, Clemens TL, Schipani E, Sabbagh Y, Xu L, Srour EF, Alvarez MB, Kacena MA, Salusky IB, Ganz T, Nemeth E, White KE. PMID: 28818868; PMCID: PMC5664401.
View in:
PubMed Mentions:
72 Fields:
Translation:
HumansAnimalsCells
-
Hamp1 mRNA and plasma hepcidin levels are influenced by sex and strain but do not predict tissue iron levels in inbred mice. Am J Physiol Gastrointest Liver Physiol. 2017 Nov 01; 313(5):G511-G523.
McLachlan S, Page KE, Lee SM, Loguinov A, Valore E, Hui ST, Jung G, Zhou J, Lusis AJ, Fuqua B, Ganz T, Nemeth E, Vulpe CD. PMID: 28798083; PMCID: PMC5792216.
View in:
PubMed Mentions:
8 Fields:
Translation:
Animals
-
Immunoassay for human serum erythroferrone. Blood. 2017 09 07; 130(10):1243-1246.
Ganz T, Jung G, Naeim A, Ginzburg Y, Pakbaz Z, Walter PB, Kautz L, Nemeth E. PMID: 28739636; PMCID: PMC5606005.
View in:
PubMed Mentions:
61 Fields:
Translation:
Humans
-
Endogenous hepcidin and its agonist mediate resistance to selected infections by clearing non-transferrin-bound iron. Blood. 2017 07 20; 130(3):245-257.
Stefanova D, Raychev A, Arezes J, Ruchala P, Gabayan V, Skurnik M, Dillon BJ, Horwitz MA, Ganz T, Bulut Y, Nemeth E. PMID: 28465342; PMCID: PMC5520472.
View in:
PubMed Mentions:
63 Fields:
Translation:
HumansAnimalsCells
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Hepcidin-mediated iron sequestration protects against bacterial dissemination during pneumonia. JCI Insight. 2017 03 23; 2(6):e92002.
Michels KR, Zhang Z, Bettina AM, Cagnina RE, Stefanova D, Burdick MD, Vaulont S, Nemeth E, Ganz T, Mehrad B. PMID: 28352667; PMCID: PMC5358492.
View in:
PubMed Mentions:
45 Fields:
Translation:
HumansAnimalsCells
-
Erythroferrone and matriptase-2 independently regulate hepcidin expression. Am J Hematol. 2017 05; 92(5):E61-E63.
Aschemeyer S, Gabayan V, Ganz T, Nemeth E, Kautz L. PMID: 28187515; PMCID: PMC5389904.
View in:
PubMed Mentions:
18 Fields:
Translation:
Animals
-
Regulation of the Iron Homeostatic Hormone Hepcidin. Adv Nutr. 2017 01; 8(1):126-136.
Sangkhae V, Nemeth E. PMID: 28096133; PMCID: PMC5227985.
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PubMed Mentions:
171 Fields:
Translation:
HumansAnimalsCells
-
Increased serum hepcidin contributes to the anemia of chronic kidney disease in a murine model. Haematologica. 2017 03; 102(3):e85-e88.
Hanudel MR, Rappaport M, Gabayan V, Jung G, Salusky IB, Nemeth E, Ganz T, Zaritsky J. PMID: 27884972; PMCID: PMC5394962.
View in:
PubMed Mentions:
9 Fields:
Translation:
HumansAnimals
-
Iron Metabolism in African American Women in the Second and Third Trimesters of High-Risk Pregnancies. J Obstet Gynecol Neonatal Nurs. 2017 Jan - Feb; 46(1):148-158.
Welke L, Koenig MD, Thomson JL, Nemeth E, White-Traut R, McFarlin BL, Giurgescu C, Engeland CG, Kominiarek MA, Tussing-Humphreys L. PMID: 27836659; PMCID: PMC6459009.
View in:
PubMed Mentions:
2 Fields:
Translation:
Humans
-
Effects of dietary iron intake and chronic kidney disease on fibroblast growth factor 23 metabolism in wild-type and hepcidin knockout mice. Am J Physiol Renal Physiol. 2016 12 01; 311(6):F1369-F1377.
Hanudel MR, Chua K, Rappaport M, Gabayan V, Valore E, Goltzman D, Ganz T, Nemeth E, Salusky IB. PMID: 27733366; PMCID: PMC5210202.
View in:
PubMed Mentions:
41 Fields:
Translation:
Animals
-
Minihepcidin peptides as disease modifiers in mice affected by β-thalassemia and polycythemia vera. Blood. 2016 07 14; 128(2):265-76.
Casu C, Oikonomidou PR, Chen H, Nandi V, Ginzburg Y, Prasad P, Fleming RE, Shah YM, Valore EV, Nemeth E, Ganz T, MacDonald B, Rivella S. PMID: 27154187; PMCID: PMC4946204.
View in:
PubMed Mentions:
68 Fields:
Translation:
Animals
-
Hepcidin in the diagnosis of iron disorders. Blood. 2016 06 09; 127(23):2809-13.
Girelli D, Nemeth E, Swinkels DW. PMID: 27044621; PMCID: PMC4956612.
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PubMed Mentions:
140 Fields:
Translation:
HumansAnimals
-
Iron Balance and the Role of Hepcidin in Chronic Kidney Disease. Semin Nephrol. 2016 03; 36(2):87-93.
Ganz T, Nemeth E. PMID: 27236128; PMCID: PMC4884601.
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PubMed Mentions:
68 Fields:
Translation:
HumansCells
-
Ironing out Ferroportin. Cell Metab. 2015 Nov 03; 22(5):777-87.
Drakesmith H, Nemeth E, Ganz T. PMID: 26437604; PMCID: PMC4635047.
View in:
PubMed Mentions:
277 Fields:
Translation:
HumansAnimalsCells
-
Isocitrate treatment of acute anemia of inflammation in a mouse model. Blood Cells Mol Dis. 2016 Jan; 56(1):31-6.
Kim A, Fung E, Parikh SG, Gabayan V, Nemeth E, Ganz T. PMID: 26603720; PMCID: PMC4660302.
View in:
PubMed Mentions:
7 Fields:
Translation:
AnimalsCells
-
Hepcidin and Host Defense against Infectious Diseases. PLoS Pathog. 2015 Aug; 11(8):e1004998.
Michels K, Nemeth E, Ganz T, Mehrad B. PMID: 26291319; PMCID: PMC4546197.
View in:
PubMed Mentions:
82 Fields:
Translation:
HumansAnimals
-
Erythroferrone contributes to hepcidin suppression and iron overload in a mouse model of β-thalassemia. Blood. 2015 Oct 22; 126(17):2031-7.
Kautz L, Jung G, Du X, Gabayan V, Chapman J, Nasoff M, Nemeth E, Ganz T. PMID: 26276665; PMCID: PMC4616236.
View in:
PubMed Mentions:
141 Fields:
Translation:
Animals
-
Iron homeostasis in host defence and inflammation. Nat Rev Immunol. 2015 Aug; 15(8):500-10.
Ganz T, Nemeth E. PMID: 26160612; PMCID: PMC4801113.
View in:
PubMed Mentions:
332 Fields:
Translation:
HumansAnimalsCells
-
New insights into iron regulation and erythropoiesis. Curr Opin Hematol. 2015 May; 22(3):199-205.
Kim A, Nemeth E. PMID: 25710710; PMCID: PMC4509743.
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PubMed Mentions:
74 Fields:
Translation:
Humans
-
Evidence that the expression of transferrin receptor 1 on erythroid marrow cells mediates hepcidin suppression in the liver. Exp Hematol. 2015 Jun; 43(6):469-78.e6.
Keel SB, Doty R, Liu L, Nemeth E, Cherian S, Ganz T, Abkowitz JL. PMID: 25782630; PMCID: PMC4771411.
View in:
PubMed Mentions:
14 Fields:
Translation:
AnimalsCells
-
Small cyclic agonists of iron regulatory hormone hepcidin. Bioorg Med Chem Lett. 2015 Nov 01; 25(21):4961-4969.
Chua K, Fung E, Micewicz ED, Ganz T, Nemeth E, Ruchala P. PMID: 25813158; PMCID: PMC4567957.
View in:
PubMed Mentions:
16 Fields:
Translation:
HumansCells
-
Hepcidin-induced hypoferremia is a critical host defense mechanism against the siderophilic bacterium Vibrio vulnificus. Cell Host Microbe. 2015 Jan 14; 17(1):47-57.
Arezes J, Jung G, Gabayan V, Valore E, Ruchala P, Gulig PA, Ganz T, Nemeth E, Bulut Y. PMID: 25590758; PMCID: PMC4296238.
View in:
PubMed Mentions:
121 Fields:
Translation:
AnimalsCells
-
Thiol-derivatized minihepcidins retain biological activity. Bioorg Med Chem Lett. 2015 Feb 15; 25(4):763-6.
Fung E, Chua K, Ganz T, Nemeth E, Ruchala P. PMID: 25599838; PMCID: PMC4318710.
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PubMed Mentions:
13 Fields:
-
A competitive enzyme-linked immunosorbent assay specific for murine hepcidin-1: correlation with hepatic mRNA expression in established and novel models of dysregulated iron homeostasis. Haematologica. 2015 Feb; 100(2):167-77.
Gutschow P, Schmidt PJ, Han H, Ostland V, Bartnikas TB, Pettiglio MA, Herrera C, Butler JS, Nemeth E, Ganz T, Fleming MD, Westerman M. PMID: 25425686; PMCID: PMC4803145.
View in:
PubMed Mentions:
17 Fields:
Translation:
HumansAnimalsCells
-
Erythroferrone contributes to recovery from anemia of inflammation. Blood. 2014 Oct 16; 124(16):2569-74.
Kautz L, Jung G, Nemeth E, Ganz T. PMID: 25193872; PMCID: PMC4199959.
View in:
PubMed Mentions:
66 Fields:
Translation:
AnimalsCells
-
Hepcidin and iron homeostasis during pregnancy. Nutrients. 2014 Aug 04; 6(8):3062-83.
Koenig MD, Tussing-Humphreys L, Day J, Cadwell B, Nemeth E. PMID: 25093277; PMCID: PMC4145295.
View in:
PubMed Mentions:
71 Fields:
Translation:
HumansAnimals
-
Disordered hepcidin-ferroportin signaling promotes breast cancer growth. Cell Signal. 2014 Nov; 26(11):2539-50.
Zhang S, Chen Y, Guo W, Yuan L, Zhang D, Xu Y, Nemeth E, Ganz T, Liu S. PMID: 25093806.
View in:
PubMed Mentions:
55 Fields:
Translation:
HumansCells
-
Identification of erythroferrone as an erythroid regulator of iron metabolism. Nat Genet. 2014 Jul; 46(7):678-84.
Kautz L, Jung G, Valore EV, Rivella S, Nemeth E, Ganz T. PMID: 24880340; PMCID: PMC4104984.
View in:
PubMed Mentions:
448 Fields:
Translation:
Animals
-
Molecular liaisons between erythropoiesis and iron metabolism. Blood. 2014 Jul 24; 124(4):479-82.
Kautz L, Nemeth E. PMID: 24876565; PMCID: PMC4110655.
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PubMed Mentions:
53 Fields:
Translation:
HumansAnimals
-
Anemia of inflammation. Hematol Oncol Clin North Am. 2014 Aug; 28(4):671-81, vi.
Nemeth E, Ganz T. PMID: 25064707; PMCID: PMC4115203.
View in:
PubMed Mentions:
158 Fields:
Translation:
Humans
-
Systemic and tumor level iron regulation in men with colorectal cancer: a case control study. Nutr Metab (Lond). 2014; 11:21.
Pusatcioglu CK, Nemeth E, Fantuzzi G, Llor X, Freels S, Tussing-Humphreys L, Cabay RJ, Linzmeier R, Ng D, Clark J, Braunschweig C. PMID: 24872837; PMCID: PMC4037273.
View in:
PubMed Mentions:
6
-
Mouse models of anemia of cancer. PLoS One. 2014; 9(3):e93283.
Kim A, Rivera S, Shprung D, Limbrick D, Gabayan V, Nemeth E, Ganz T. PMID: 24681760; PMCID: PMC3969362.
View in:
PubMed Mentions:
14 Fields:
Translation:
AnimalsCells
-
The pathophysiology and pharmacology of hepcidin. Trends Pharmacol Sci. 2014 Mar; 35(3):155-61.
Ruchala P, Nemeth E. PMID: 24552640; PMCID: PMC3978192.
View in:
PubMed Mentions:
59 Fields:
Translation:
HumansAnimals
-
Total synthesis of human hepcidin through regioselective disulfide-bond formation by using the safety-catch cysteine protecting group 4,4'-dimethylsulfinylbenzhydryl. Angew Chem Int Ed Engl. 2014 Mar 10; 53(11):2931-4.
Dekan Z, Mobli M, Pennington MW, Fung E, Nemeth E, Alewood PF. PMID: 24604812.
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PubMed Mentions:
5 Fields:
Translation:
HumansCells
-
A mouse model of anemia of inflammation: complex pathogenesis with partial dependence on hepcidin. Blood. 2014 Feb 20; 123(8):1129-36.
Kim A, Fung E, Parikh SG, Valore EV, Gabayan V, Nemeth E, Ganz T. PMID: 24357728; PMCID: PMC9632791.
View in:
PubMed Mentions:
78 Fields:
Translation:
HumansAnimalsCells
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Testing the iron hypothesis in a mouse model of atherosclerosis. Cell Rep. 2013 Dec 12; 5(5):1436-42.
Kautz L, Gabayan V, Wang X, Wu J, Onwuzurike J, Jung G, Qiao B, Lusis AJ, Ganz T, Nemeth E. PMID: 24316081; PMCID: PMC3880128.
View in:
PubMed Mentions:
24 Fields:
Translation:
AnimalsCells
-
Functional properties of human ferroportin, a cellular iron exporter reactive also with cobalt and zinc. Am J Physiol Cell Physiol. 2014 Mar 01; 306(5):C450-9.
Mitchell CJ, Shawki A, Ganz T, Nemeth E, Mackenzie B. PMID: 24304836; PMCID: PMC4042619.
View in:
PubMed Mentions:
57 Fields:
Translation:
HumansAnimalsCells
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Hepcidin induction by pathogens and pathogen-derived molecules is strongly dependent on interleukin-6. Infect Immun. 2014 Feb; 82(2):745-52.
Rodriguez R, Jung CL, Gabayan V, Deng JC, Ganz T, Nemeth E, Bulut Y. PMID: 24478088; PMCID: PMC3911381.
View in:
PubMed Mentions:
56 Fields:
Translation:
HumansAnimalsCells
-
Manipulation of the hepcidin pathway for therapeutic purposes. Haematologica. 2013 Nov; 98(11):1667-76.
Fung E, Nemeth E. PMID: 24186312; PMCID: PMC3815165.
View in:
PubMed Mentions:
51 Fields:
Translation:
HumansAnimalsCells
-
Anti-hepcidin therapy for iron-restricted anemias. Blood. 2013 Oct 24; 122(17):2929-31.
Nemeth E. PMID: 24159166; PMCID: PMC8940288.
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PubMed Mentions:
6 Fields:
Translation:
HumansAnimalsCells
-
Design, synthesis, and characterization of cyclic analogues of the iron regulatory peptide hormone hepcidin. Biopolymers. 2013 Sep; 100(5):519-26.
Clark RJ, Preza GC, Tan CC, van Dijk JW, Fung E, Nemeth E, Ganz T, Craik DJ. PMID: 23897622.
View in:
PubMed Mentions:
4 Fields:
Translation:
HumansAnimalsCells
-
Hepcidin and β-thalassemia major. Blood. 2013 Jul 04; 122(1):3-4.
Nemeth E. PMID: 23828883.
View in:
PubMed Mentions:
13 Fields:
Translation:
Humans
-
Cellular catabolism of the iron-regulatory peptide hormone hepcidin. PLoS One. 2013; 8(3):e58934.
Preza GC, Pinon R, Ganz T, Nemeth E. PMID: 23536837; PMCID: PMC3594189.
View in:
PubMed Mentions:
18 Fields:
Translation:
HumansCells
-
Testosterone administration inhibits hepcidin transcription and is associated with increased iron incorporation into red blood cells. Aging Cell. 2013 Apr; 12(2):280-91.
Guo W, Bachman E, Li M, Roy CN, Blusztajn J, Wong S, Chan SY, Serra C, Jasuja R, Travison TG, Muckenthaler MU, Nemeth E, Bhasin S. PMID: 23399021; PMCID: PMC3602280.
View in:
PubMed Mentions:
65 Fields:
Translation:
HumansAnimalsCells
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Hepcidin level predicts hemoglobin concentration in individuals undergoing repeated phlebotomy. Haematologica. 2013 Aug; 98(8):1324-30.
Mast AE, Schlumpf KS, Wright DJ, Johnson B, Glynn SA, Busch MP, Olbina G, Westerman M, Nemeth E, Ganz T, NHLBI Retrovirus Epidemiology Donor Study-II (REDS-II). PMID: 23445875; PMCID: PMC3729915.
View in:
PubMed Mentions:
10 Fields:
Translation:
HumansCTClinical Trials
-
High-throughput screening of small molecules identifies hepcidin antagonists. Mol Pharmacol. 2013 Mar; 83(3):681-90.
Fung E, Sugianto P, Hsu J, Damoiseaux R, Ganz T, Nemeth E. PMID: 23292796; PMCID: PMC3583499.
View in:
PubMed Mentions:
35 Fields:
Translation:
HumansAnimalsCells
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Hepcidin is a key mediator of anemia of inflammation in Crohn's disease. J Crohns Colitis. 2013 Sep; 7(8):e286-91.
Basseri RJ, Nemeth E, Vassilaki ME, Basseri B, Enayati P, Shaye O, Bourikas LA, Ganz T, Papadakis KA. PMID: 23219355.
View in:
PubMed Mentions:
31 Fields:
Translation:
Humans
-
Minihepcidins prevent iron overload in a hepcidin-deficient mouse model of severe hemochromatosis. Blood. 2012 Nov 01; 120(18):3829-36.
Ramos E, Ruchala P, Goodnough JB, Kautz L, Preza GC, Nemeth E, Ganz T. PMID: 22990014; PMCID: PMC3488893.
View in:
PubMed Mentions:
96 Fields:
Translation:
Animals
-
Iron homeostasis and its disorders in mice and men: potential lessons for rhinos. J Zoo Wildl Med. 2012 Sep; 43(3 Suppl):S19-26.
Ganz T, Nemeth E. PMID: 23156702.
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PubMed Mentions:
4 Fields:
Translation:
HumansAnimals
-
IOD in rhinos--immunity group report: report from the Immunity, Genetics and Toxicology Working Group of the International Workshop on Iron Overload Disorder in Browsing Rhinoceros (February 2011). J Zoo Wildl Med. 2012 Sep; 43(3 Suppl):S117-9.
Ganz T, Goff J, Klasing K, Nemeth E, Roth T. PMID: 23156715.
View in:
PubMed Mentions:
3 Fields:
Translation:
AnimalsCells
-
Inhibition of hepcidin transcription by growth factors. Hepatology. 2012 Jul; 56(1):291-9.
Goodnough JB, Ramos E, Nemeth E, Ganz T. PMID: 22278715; PMCID: PMC3362690.
View in:
PubMed Mentions:
51 Fields:
Translation:
HumansAnimalsCells
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Molecular mechanism of hepcidin-mediated ferroportin internalization requires ferroportin lysines, not tyrosines or JAK-STAT. Cell Metab. 2012 Jun 06; 15(6):905-17.
Ross SL, Tran L, Winters A, Lee KJ, Plewa C, Foltz I, King C, Miranda LP, Allen J, Beckman H, Cooke KS, Moody G, Sasu BJ, Nemeth E, Ganz T, Molineux G, Arvedson TL. PMID: 22682226.
View in:
PubMed Mentions:
66 Fields:
Translation:
HumansCells
-
Hepcidin-induced endocytosis of ferroportin is dependent on ferroportin ubiquitination. Cell Metab. 2012 Jun 06; 15(6):918-24.
Qiao B, Sugianto P, Fung E, Del-Castillo-Rueda A, Moran-Jimenez MJ, Ganz T, Nemeth E. PMID: 22682227; PMCID: PMC3372862.
View in:
PubMed Mentions:
146 Fields:
Translation:
HumansCells
-
Iron metabolism: interactions with normal and disordered erythropoiesis. Cold Spring Harb Perspect Med. 2012 May; 2(5):a011668.
Ganz T, Nemeth E. PMID: 22553501; PMCID: PMC3331689.
View in:
PubMed Mentions:
56 Fields:
Translation:
HumansCells
-
Rethinking iron regulation and assessment in iron deficiency, anemia of chronic disease, and obesity: introducing hepcidin. J Acad Nutr Diet. 2012 Mar; 112(3):391-400.
Tussing-Humphreys L, Pusatcioglu C, Pustacioglu C, Nemeth E, Braunschweig C. PMID: 22717199; PMCID: PMC3381289.
View in:
PubMed Mentions:
67 Fields:
Translation:
HumansPHPublic Health
-
Hepcidin and iron homeostasis. Biochim Biophys Acta. 2012 Sep; 1823(9):1434-43.
Ganz T, Nemeth E. PMID: 22306005; PMCID: PMC4048856.
View in:
PubMed Mentions:
509 Fields:
Translation:
HumansAnimalsCells
-
Minihepcidins are rationally designed small peptides that mimic hepcidin activity in mice and may be useful for the treatment of iron overload. J Clin Invest. 2011 Dec; 121(12):4880-8.
Preza GC, Ruchala P, Pinon R, Ramos E, Qiao B, Peralta MA, Sharma S, Waring A, Ganz T, Nemeth E. PMID: 22045566; PMCID: PMC3225996.
View in:
PubMed Mentions:
107 Fields:
Translation:
HumansAnimalsCells
-
Subcutaneous adipose tissue from obese and lean adults does not release hepcidin in vivo. ScientificWorldJournal. 2011; 11:2197-206.
Tussing-Humphreys L, Frayn KN, Smith SR, Westerman M, Dennis AL, Nemeth E, Thomson J, Pusatcioglu C. PMID: 22125467; PMCID: PMC3217603.
View in:
PubMed Mentions:
8 Fields:
Translation:
Humans
-
Serum hepcidin as a diagnostic test of iron deficiency in premenopausal female blood donors. Haematologica. 2011 Aug; 96(8):1099-105.
Pasricha SR, McQuilten Z, Westerman M, Keller A, Nemeth E, Ganz T, Wood E. PMID: 21508121; PMCID: PMC3148902.
View in:
PubMed Mentions:
38 Fields:
Translation:
Humans
-
Hepcidin response to acute iron intake and chronic iron loading in dysmetabolic iron overload syndrome. Liver Int. 2011 Aug; 31(7):994-1000.
Trombini P, Paolini V, Pelucchi S, Mariani R, Nemeth E, Ganz T, Piperno A. PMID: 21733088; PMCID: PMC4048852.
View in:
PubMed Mentions:
10 Fields:
Translation:
Humans
-
Evidence for distinct pathways of hepcidin regulation by acute and chronic iron loading in mice. Hepatology. 2011 Apr; 53(4):1333-41.
Ramos E, Kautz L, Rodriguez R, Hansen M, Gabayan V, Ginzburg Y, Roth MP, Nemeth E, Ganz T. PMID: 21480335; PMCID: PMC3074982.
View in:
PubMed Mentions:
116 Fields:
Translation:
Animals
-
Understanding the structure/activity relationships of the iron regulatory peptide hepcidin. Chem Biol. 2011 Mar 25; 18(3):336-43.
Clark RJ, Tan CC, Preza GC, Nemeth E, Ganz T, Craik DJ. PMID: 21439478; PMCID: PMC3073735.
View in:
PubMed Mentions:
13 Fields:
Translation:
HumansCells
-
Intestinal ferroportin expression in pediatric Crohn's disease. Inflamm Bowel Dis. 2011 Feb; 17(2):524-31.
Burpee T, Mitchell P, Fishman D, Islam S, Nemeth E, Westerman M, Wessling-Resnick M, Grand RJ. PMID: 20564534; PMCID: PMC3733087.
View in:
PubMed Mentions:
3 Fields:
Translation:
Humans
-
Hepcidin and disorders of iron metabolism. Annu Rev Med. 2011; 62:347-60.
Ganz T, Nemeth E. PMID: 20887198.
View in:
PubMed Mentions:
189 Fields:
Translation:
HumansAnimalsCells
-
The hepcidin-ferroportin system as a therapeutic target in anemias and iron overload disorders. Hematology Am Soc Hematol Educ Program. 2011; 2011:538-42.
Ganz T, Nemeth E. PMID: 22160086; PMCID: PMC4034574.
View in:
PubMed Mentions:
49 Fields:
Translation:
Humans
-
A time course of hepcidin response to iron challenge in patients with HFE and TFR2 hemochromatosis. Haematologica. 2011 Apr; 96(4):500-6.
Girelli D, Trombini P, Busti F, Campostrini N, Sandri M, Pelucchi S, Westerman M, Ganz T, Nemeth E, Piperno A, Camaschella C. PMID: 21173098; PMCID: PMC3069225.
View in:
PubMed Mentions:
30 Fields:
Translation:
Humans
-
Novel tools for the evaluation of iron metabolism. Haematologica. 2010 Dec; 95(12):1989-91.
Kautz L, Nemeth E. PMID: 21123438; PMCID: PMC2995554.
View in:
PubMed Mentions:
2 Fields:
Translation:
Humans
-
Hepcidin as a therapeutic tool to limit iron overload and improve anemia in β-thalassemic mice. J Clin Invest. 2010 Dec; 120(12):4466-77.
Gardenghi S, Ramos P, Marongiu MF, Melchiori L, Breda L, Guy E, Muirhead K, Rao N, Roy CN, Andrews NC, Nemeth E, Follenzi A, An X, Mohandas N, Ginzburg Y, Rachmilewitz EA, Giardina PJ, Grady RW, Rivella S. PMID: 21099112; PMCID: PMC2993583.
View in:
PubMed Mentions:
123 Fields:
Translation:
HumansAnimalsCells
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Detection, evaluation, and management of iron-restricted erythropoiesis. Blood. 2010 Dec 02; 116(23):4754-61.
Goodnough LT, Nemeth E, Ganz T. PMID: 20826717.
View in:
PubMed Mentions:
148 Fields:
Translation:
Humans
-
Crosstalk between Erythropoiesis and Iron Metabolism. Adv Hematol. 2010; 2010.
Rivella S, Nemeth E, Miller JL. PMID: 20862206; PMCID: PMC2938435.
View in:
PubMed Mentions:
2
-
In anemia of multiple myeloma, hepcidin is induced by increased bone morphogenetic protein 2. Blood. 2010 Nov 04; 116(18):3635-44.
Maes K, Nemeth E, Roodman GD, Huston A, Esteve F, Freytes C, Callander N, Katodritou E, Tussing-Humphreys L, Rivera S, Vanderkerken K, Lichtenstein A, Ganz T. PMID: 20679527; PMCID: PMC2981483.
View in:
PubMed Mentions:
54 Fields:
Translation:
HumansCells
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Hepcidin in beta-thalassemia. Ann N Y Acad Sci. 2010 Aug; 1202:31-5.
Nemeth E. PMID: 20712769; PMCID: PMC2924878.
View in:
PubMed Mentions:
32 Fields:
Translation:
Humans
-
Alpha 1-acid glycoprotein, hepcidin, C-reactive protein, and serum ferritin are correlated in anemic schoolchildren with Schistosoma haematobium. Am J Clin Nutr. 2010 Jun; 91(6):1784-90.
Ayoya MA, Spiekermann-Brouwer GM, Stoltzfus RJ, Nemeth E, Habicht JP, Ganz T, Rawat R, Traoré AK, Garza C. PMID: 20410090.
View in:
PubMed Mentions:
19 Fields:
Translation:
HumansAnimals
-
Hepcidin biology and therapeutic applications. Expert Rev Hematol. 2010 Apr; 3(2):153-5.
Nemeth E. PMID: 21083458.
View in:
PubMed Mentions:
6 Fields:
Translation:
Humans
-
Reduction of serum hepcidin by hemodialysis in pediatric and adult patients. Clin J Am Soc Nephrol. 2010 Jun; 5(6):1010-4.
Zaritsky J, Young B, Gales B, Wang HJ, Rastogi A, Westerman M, Nemeth E, Ganz T, Salusky IB. PMID: 20299375; PMCID: PMC2879302.
View in:
PubMed Mentions:
33 Fields:
Translation:
HumansCells
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Proinflammatory state, hepcidin, and anemia in older persons. Blood. 2010 May 06; 115(18):3810-6.
Ferrucci L, Semba RD, Guralnik JM, Ershler WB, Bandinelli S, Patel KV, Sun K, Woodman RC, Andrews NC, Cotter RJ, Ganz T, Nemeth E, Longo DL. PMID: 20081092; PMCID: PMC2865871.
View in:
PubMed Mentions:
87 Fields:
Translation:
Humans
-
Decreased serum hepcidin and improved functional iron status 6 months after restrictive bariatric surgery. Obesity (Silver Spring). 2010 Oct; 18(10):2010-6.
Tussing-Humphreys LM, Nemeth E, Fantuzzi G, Freels S, Holterman AX, Galvani C, Ayloo S, Vitello J, Braunschweig C. PMID: 20075851.
View in:
PubMed Mentions:
34 Fields:
Translation:
Humans
-
Targeting the hepcidin-ferroportin axis in the diagnosis and treatment of anemias. Adv Hematol. 2010; 2010:750643.
Nemeth E. PMID: 20066043; PMCID: PMC2798567.
View in:
PubMed Mentions:
25
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The role of hepcidin in iron metabolism. Acta Haematol. 2009; 122(2-3):78-86.
Nemeth E, Ganz T. PMID: 19907144; PMCID: PMC2855274.
View in:
PubMed Mentions:
191 Fields:
Translation:
HumansCells
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Elevated systemic hepcidin and iron depletion in obese premenopausal females. Obesity (Silver Spring). 2010 Jul; 18(7):1449-56.
Tussing-Humphreys LM, Nemeth E, Fantuzzi G, Freels S, Guzman G, Holterman AX, Braunschweig C. PMID: 19816411.
View in:
PubMed Mentions:
55 Fields:
Translation:
Humans
-
Iron sequestration and anemia of inflammation. Semin Hematol. 2009 Oct; 46(4):387-93.
Ganz T, Nemeth E. PMID: 19786207; PMCID: PMC2755591.
View in:
PubMed Mentions:
135 Fields:
Translation:
HumansCells
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Reduced serum hepcidin levels in patients with chronic hepatitis C. J Hepatol. 2009 Nov; 51(5):845-52.
Girelli D, Pasino M, Goodnough JB, Nemeth E, Guido M, Castagna A, Busti F, Campostrini N, Martinelli N, Vantini I, Corrocher R, Ganz T, Fattovich G. PMID: 19729219; PMCID: PMC2761995.
View in:
PubMed Mentions:
69 Fields:
Translation:
HumansAnimals
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Hereditary hemochromatosis due to resistance to hepcidin: high hepcidin concentrations in a family with C326S ferroportin mutation. Blood. 2009 Jul 09; 114(2):493-4.
Sham RL, Phatak PD, Nemeth E, Ganz T. PMID: 19589941; PMCID: PMC2714220.
View in:
PubMed Mentions:
27 Fields:
Translation:
Humans
-
Hepcidin--a potential novel biomarker for iron status in chronic kidney disease. Clin J Am Soc Nephrol. 2009 Jun; 4(6):1051-6.
Zaritsky J, Young B, Wang HJ, Westerman M, Olbina G, Nemeth E, Ganz T, Rivera S, Nissenson AR, Salusky IB. PMID: 19406957; PMCID: PMC2689881.
View in:
PubMed Mentions:
126 Fields:
Translation:
HumansCTClinical Trials
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The molecular basis of hepcidin-resistant hereditary hemochromatosis. Blood. 2009 Jul 09; 114(2):437-43.
Fernandes A, Preza GC, Phung Y, De Domenico I, Kaplan J, Ganz T, Nemeth E. PMID: 19383972; PMCID: PMC2714214.
View in:
PubMed Mentions:
59 Fields:
Translation:
HumansCells
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Iron absorption in dysmetabolic iron overload syndrome is decreased and correlates with increased plasma hepcidin. J Hepatol. 2009 Jun; 50(6):1219-25.
Ruivard M, Lainé F, Ganz T, Olbina G, Westerman M, Nemeth E, Rambeau M, Mazur A, Gerbaud L, Tournilhac V, Abergel A, Philippe P, Deugnier Y, Coudray C. PMID: 19398238.
View in:
PubMed Mentions:
20 Fields:
Translation:
Humans
-
Daily regulation of serum and urinary hepcidin is not influenced by submaximal cycling exercise in humans with normal iron metabolism. Eur J Appl Physiol. 2009 Jun; 106(3):435-43.
Troadec MB, Lainé F, Daniel V, Rochcongar P, Ropert M, Cabillic F, Perrin M, Morcet J, Loréal O, Olbina G, Westerman M, Nemeth E, Ganz T, Brissot P. PMID: 19306018.
View in:
PubMed Mentions:
11 Fields:
Translation:
Humans
-
Excess adiposity, inflammation, and iron-deficiency in female adolescents. J Am Diet Assoc. 2009 Feb; 109(2):297-302.
Tussing-Humphreys LM, Liang H, Nemeth E, Freels S, Braunschweig CA. PMID: 19167957.
View in:
PubMed Mentions:
43 Fields:
Translation:
Humans
-
Immunoassay for human serum hepcidin. Blood. 2008 Nov 15; 112(10):4292-7.
Ganz T, Olbina G, Girelli D, Nemeth E, Westerman M. PMID: 18689548.
View in:
PubMed Mentions:
269 Fields:
Translation:
Humans
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The hepcidin-binding site on ferroportin is evolutionarily conserved. Cell Metab. 2008 Aug; 8(2):146-56.
De Domenico I, Nemeth E, Nelson JM, Phillips JD, Ajioka RS, Kay MS, Kushner JP, Ganz T, Ward DM, Kaplan J. PMID: 18680715; PMCID: PMC2660598.
View in:
PubMed Mentions:
56 Fields:
Translation:
HumansAnimalsCells
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Involvement of hepcidin in the anemia of multiple myeloma. Clin Cancer Res. 2008 Jun 01; 14(11):3262-7.
Sharma S, Nemeth E, Chen YH, Goodnough J, Huston A, Roodman GD, Ganz T, Lichtenstein A. PMID: 18519751.
View in:
PubMed Mentions:
45 Fields:
Translation:
HumansCells
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Urinary hepcidin excretion in patients with myelodysplastic syndrome and myelofibrosis. Br J Haematol. 2008 Aug; 142(4):669-71.
Winder A, Lefkowitz R, Ghoti H, Leiba M, Ganz T, Nemeth E, Rachmilewitz EA. PMID: 18498424.
View in:
PubMed Mentions:
8 Fields:
Translation:
Humans
-
Iron regulation and erythropoiesis. Curr Opin Hematol. 2008 May; 15(3):169-75.
Nemeth E. PMID: 18391780.
View in:
PubMed Mentions:
61 Fields:
Translation:
Humans
-
Hepcidin and iron-related gene expression in subjects with Dysmetabolic Hepatic Iron Overload. J Hepatol. 2008 Jul; 49(1):123-33.
Barisani D, Pelucchi S, Mariani R, Galimberti S, Trombini P, Fumagalli D, Meneveri R, Nemeth E, Ganz T, Piperno A. PMID: 18462824.
View in:
PubMed Mentions:
33 Fields:
Translation:
Humans
-
Measurement of urinary hepcidin levels by SELDI-TOF-MS in HFE-hemochromatosis. Blood Cells Mol Dis. 2008 May-Jun; 40(3):347-52.
Bozzini C, Campostrini N, Trombini P, Nemeth E, Castagna A, Tenuti I, Corrocher R, Camaschella C, Ganz T, Olivieri O, Piperno A, Girelli D. PMID: 18164223.
View in:
PubMed Mentions:
18 Fields:
Translation:
Humans
-
Effects of plasma transfusion on hepcidin production in human congenital hypotransferrinemia. Haematologica. 2007 Oct; 92(10):1407-10.
Trombini P, Coliva T, Nemeth E, Mariani R, Ganz T, Biondi A, Piperno A. PMID: 17768112.
View in:
PubMed Mentions:
19 Fields:
Translation:
Humans
-
Soluble hemojuvelin is released by proprotein convertase-mediated cleavage at a conserved polybasic RNRR site. Blood Cells Mol Dis. 2008 Jan-Feb; 40(1):122-31.
Lin L, Nemeth E, Goodnough JB, Thapa DR, Gabayan V, Ganz T. PMID: 17869549; PMCID: PMC2211380.
View in:
PubMed Mentions:
43 Fields:
Translation:
HumansAnimalsCells
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Blunted hepcidin response to oral iron challenge in HFE-related hemochromatosis. Blood. 2007 Dec 01; 110(12):4096-100.
Piperno A, Girelli D, Nemeth E, Trombini P, Bozzini C, Poggiali E, Phung Y, Ganz T, Camaschella C. PMID: 17724144.
View in:
PubMed Mentions:
58 Fields:
Translation:
Humans
-
Iron transferrin regulates hepcidin synthesis in primary hepatocyte culture through hemojuvelin and BMP2/4. Blood. 2007 Sep 15; 110(6):2182-9.
Lin L, Valore EV, Nemeth E, Goodnough JB, Gabayan V, Ganz T. PMID: 17540841; PMCID: PMC1976373.
View in:
PubMed Mentions:
111 Fields:
Translation:
HumansAnimalsCells
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The molecular mechanism of hepcidin-mediated ferroportin down-regulation. Mol Biol Cell. 2007 Jul; 18(7):2569-78.
De Domenico I, Ward DM, Langelier C, Vaughn MB, Nemeth E, Sundquist WI, Ganz T, Musci G, Kaplan J. PMID: 17475779; PMCID: PMC1924807.
View in:
PubMed Mentions:
158 Fields:
Translation:
HumansAnimalsCells
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Liver iron concentrations and urinary hepcidin in beta-thalassemia. Haematologica. 2007 May; 92(5):583-8.
Origa R, Galanello R, Ganz T, Giagu N, Maccioni L, Faa G, Nemeth E. PMID: 17488680.
View in:
PubMed Mentions:
136 Fields:
Translation:
HumansCells
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Urinary hepcidin in congenital chronic anemias. Pediatr Blood Cancer. 2007 Jan; 48(1):57-63.
Kearney SL, Nemeth E, Neufeld EJ, Thapa D, Ganz T, Weinstein DA, Cunningham MJ. PMID: 16220548.
View in:
PubMed Mentions:
60 Fields:
Translation:
HumansCTClinical Trials
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Impaired intestinal iron absorption in Crohn's disease correlates with disease activity and markers of inflammation. Inflamm Bowel Dis. 2006 Dec; 12(12):1101-6.
Semrin G, Fishman DS, Bousvaros A, Zholudev A, Saunders AC, Correia CE, Nemeth E, Grand RJ, Weinstein DA. PMID: 17119383; PMCID: PMC2788427.
View in:
PubMed Mentions:
63 Fields:
Translation:
Humans
-
Molecular and clinical correlates in iron overload associated with mutations in ferroportin. Haematologica. 2006 Aug; 91(8):1092-5.
De Domenico I, McVey Ward D, Nemeth E, Ganz T, Corradini E, Ferrara F, Musci G, Pietrangelo A, Kaplan J. PMID: 16885049; PMCID: PMC3718284.
View in:
PubMed Mentions:
19 Fields:
Translation:
Humans
-
DMT1 mutation: response of anemia to darbepoetin administration and implications for iron homeostasis. Blood. 2006 Jul 01; 108(1):404-5.
Pospisilova D, Mims MP, Nemeth E, Ganz T, Prchal JT. PMID: 16790587; PMCID: PMC1895846.
View in:
PubMed Mentions:
5 Fields:
Translation:
Humans
-
Hepcidin and iron-loading anemias. Haematologica. 2006 Jun; 91(6):727-32.
Nemeth E, Ganz T. PMID: 16769573.
View in:
PubMed Mentions:
40 Fields:
Translation:
Humans
-
Regulation of iron acquisition and iron distribution in mammals. Biochim Biophys Acta. 2006 Jul; 1763(7):690-9.
Ganz T, Nemeth E. PMID: 16790283.
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PubMed Mentions:
83 Fields:
Translation:
AnimalsCells
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Iron imports. IV. Hepcidin and regulation of body iron metabolism. Am J Physiol Gastrointest Liver Physiol. 2006 Feb; 290(2):G199-203.
Ganz T, Nemeth E. PMID: 16407589.
View in:
PubMed Mentions:
101 Fields:
Translation:
HumansAnimalsCells
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Regulation of iron metabolism by hepcidin. Annu Rev Nutr. 2006; 26:323-42.
Nemeth E, Ganz T. PMID: 16848710.
View in:
PubMed Mentions:
247 Fields:
Translation:
Humans
-
The N-terminus of hepcidin is essential for its interaction with ferroportin: structure-function study. Blood. 2006 Jan 01; 107(1):328-33.
Nemeth E, Preza GC, Jung CL, Kaplan J, Waring AJ, Ganz T. PMID: 16141345; PMCID: PMC1895343.
View in:
PubMed Mentions:
75 Fields:
Translation:
AnimalsCells
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Primary iron overload with inappropriate hepcidin expression in V162del ferroportin disease. Hepatology. 2005 Aug; 42(2):466-72.
Zoller H, McFarlane I, Theurl I, Stadlmann S, Nemeth E, Oxley D, Ganz T, Halsall DJ, Cox TM, Vogel W. PMID: 15986403.
View in:
PubMed Mentions:
19 Fields:
Translation:
Humans
-
Novel urine hepcidin assay by mass spectrometry. Blood. 2005 Nov 01; 106(9):3268-70.
Kemna E, Tjalsma H, Laarakkers C, Nemeth E, Willems H, Swinkels D. PMID: 16030189.
View in:
PubMed Mentions:
35 Fields:
Translation:
Humans
-
The molecular basis of ferroportin-linked hemochromatosis. Proc Natl Acad Sci U S A. 2005 Jun 21; 102(25):8955-60.
De Domenico I, Ward DM, Nemeth E, Vaughn MB, Musci G, Ganz T, Kaplan J. PMID: 15956209; PMCID: PMC1157058.
View in:
PubMed Mentions:
72 Fields:
Translation:
HumansAnimalsCells
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Synthetic hepcidin causes rapid dose-dependent hypoferremia and is concentrated in ferroportin-containing organs. Blood. 2005 Sep 15; 106(6):2196-9.
Rivera S, Nemeth E, Gabayan V, Lopez MA, Farshidi D, Ganz T. PMID: 15933050; PMCID: PMC1895137.
View in:
PubMed Mentions:
97 Fields:
Translation:
HumansAnimalsCells
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Time-course analysis of hepcidin, serum iron, and plasma cytokine levels in humans injected with LPS. Blood. 2005 Sep 01; 106(5):1864-6.
Kemna E, Pickkers P, Nemeth E, van der Hoeven H, Swinkels D. PMID: 15886319.
View in:
PubMed Mentions:
158 Fields:
Translation:
Humans
-
Hepcidin levels in humans are correlated with hepatic iron stores, hemoglobin levels, and hepatic function. Blood. 2005 Jul 15; 106(2):746-8.
Détivaud L, Nemeth E, Boudjema K, Turlin B, Troadec MB, Leroyer P, Ropert M, Jacquelinet S, Courselaud B, Ganz T, Brissot P, Loréal O. PMID: 15797999.
View in:
PubMed Mentions:
52 Fields:
Translation:
HumansCells
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Hepcidin in iron overload disorders. Blood. 2005 May 15; 105(10):4103-5.
Papanikolaou G, Tzilianos M, Christakis JI, Bogdanos D, Tsimirika K, MacFarlane J, Goldberg YP, Sakellaropoulos N, Ganz T, Nemeth E. PMID: 15671438; PMCID: PMC1895089.
View in:
PubMed Mentions:
132 Fields:
Translation:
Humans
-
Hepcidin regulates cellular iron efflux by binding to ferroportin and inducing its internalization. Science. 2004 Dec 17; 306(5704):2090-3.
Nemeth E, Tuttle MS, Powelson J, Vaughn MB, Donovan A, Ward DM, Ganz T, Kaplan J. PMID: 15514116.
View in:
PubMed Mentions:
1835 Fields:
Translation:
HumansAnimalsCells
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Hepcidin is decreased in TFR2 hemochromatosis. Blood. 2005 Feb 15; 105(4):1803-6.
Nemeth E, Roetto A, Garozzo G, Ganz T, Camaschella C. PMID: 15486069.
View in:
PubMed Mentions:
143 Fields:
Translation:
Humans
-
Hepcidin excess induces the sequestration of iron and exacerbates tumor-associated anemia. Blood. 2005 Feb 15; 105(4):1797-802.
Rivera S, Liu L, Nemeth E, Gabayan V, Sorensen OE, Ganz T. PMID: 15479721.
View in:
PubMed Mentions:
53 Fields:
Translation:
HumansAnimalsCells
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IL-6 mediates hypoferremia of inflammation by inducing the synthesis of the iron regulatory hormone hepcidin. J Clin Invest. 2004 May; 113(9):1271-6.
Nemeth E, Rivera S, Gabayan V, Keller C, Taudorf S, Pedersen BK, Ganz T. PMID: 15124018; PMCID: PMC398432.
View in:
PubMed Mentions:
909 Fields:
Translation:
HumansAnimalsCells
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Mutations in HFE2 cause iron overload in chromosome 1q-linked juvenile hemochromatosis. Nat Genet. 2004 Jan; 36(1):77-82.
Papanikolaou G, Samuels ME, Ludwig EH, MacDonald ML, Franchini PL, Dubé MP, Andres L, MacFarlane J, Sakellaropoulos N, Politou M, Nemeth E, Thompson J, Risler JK, Zaborowska C, Babakaiff R, Radomski CC, Pape TD, Davidas O, Christakis J, Brissot P, Lockitch G, Ganz T, Hayden MR, Goldberg YP. PMID: 14647275.
View in:
PubMed Mentions:
297 Fields:
Translation:
HumansCells
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Hepcidin, a putative mediator of anemia of inflammation, is a type II acute-phase protein. Blood. 2003 Apr 01; 101(7):2461-3.
Nemeth E, Valore EV, Territo M, Schiller G, Lichtenstein A, Ganz T. PMID: 12433676.
View in:
PubMed Mentions:
446 Fields:
Translation:
HumansCells