Soban Umar

Title(s)Associate Professor-in-Residence, Anesthesiology
SchoolMedicine
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    Collapse Biography 
    Collapse Awards and Honors
    American Thoracic Society (ATS)2021Assembly on Pulmonary Circulation Early Career Research Achievement Award
    UCLA Department of Anesthesiology and Perioperative Medicine2019Dillon Award For outstanding performance as an Assistant Professor
    Association of University Anesthesiologists (AUA)2017Junior Faculty Research Award
    UCLA2023Thomas M. Grove Chair in Anesthesiology

    Collapse Overview 
    Collapse Websites

    Collapse Research 
    Collapse Research Activities and Funding
    Investigating the molecular mechanisms of right ventricular failure in pulmonary hypertension
    NIH 1R01HL161038-01A1Sep 1, 2022 - Jun 30, 2027
    Role: Principal Investigator
    Role of the Novel MicroRNA-125b in Pulmonary Hypertension Associated with Pulmonary Fibrosis
    NIH K08HL141995May 1, 2019 - Apr 30, 2024
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Integrative Multiomics in the Lung Reveals a Protective Role of Asporin in Pulmonary Arterial Hypertension. Circulation. 2024 Oct 15; 150(16):1268-1287. Hong J, Medzikovic L, Sun W, Wong B, Ruffenach G, Rhodes CJ, Brownstein A, Liang LL, Aryan L, Li M, Vadgama A, Kurt Z, Schwantes-An TH, Mickler EA, Gräf S, Eyries M, Lutz KA, Pauciulo MW, Trembath RC, Perros F, Montani D, Morrell NW, Soubrier F, Wilkins MR, Nichols WC, Aldred MA, Desai AA, Trégouët DA, Umar S, Saggar R, Channick R, Tuder RM, Geraci MW, Stearman RS, Yang X, Eghbali M. PMID: 39167456; PMCID: PMC11473243.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    2. Dissecting the lung transcriptome of pulmonary fibrosis-associated pulmonary hypertension. Am J Physiol Lung Cell Mol Physiol. 2024 Oct 01; 327(4):L520-L534. Brownstein AJ, Mura M, Ruffenach G, Channick RN, Saggar R, Kim A, Umar S, Eghbali M, Yang X, Hong J. PMID: 39137526; PMCID: PMC11482468.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    3. Cardiac function is regulated by the sodium-dependent inhibition of the sodium-calcium exchanger NCX1. Nat Commun. 2024 May 07; 15(1):3831. Scranton K, John S, Angelini M, Steccanella F, Umar S, Zhang R, Goldhaber JI, Olcese R, Ottolia M. PMID: 38714663; PMCID: PMC11076594.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    4. RV-specific Targeting of Snai1 Rescues Pulmonary Hypertension-induced Right Ventricular Failure by Inhibiting EndMT and Fibrosis via LOXL2 Mediated Mechanism. bioRxiv. 2024 May 03. Banerjee S, Onwunyi VRC, Hong J, Martineau S, Fishbein GA, Bonnet SB, Provencher S, Bonnet S, Umar S. PMID: 38746200; PMCID: PMC11092652.
      View in: PubMed   Mentions:
    5. Effects of activity levels on aortic calcification in hyperlipidemic mice as measured by microPETmicroCT. Atherosclerosis. 2023 09; 380:117198. Hon A, Hsu JJ, Zambrano A, Xia Y, Lu M, Echeverri D, Kalanski S, Umar S, Demer LL, Tintut Y. PMID: 37579593; PMCID: PMC11146201.
      View in: PubMed   Mentions:    Fields:    Translation:Animals
    6. Ventilation and Complications after Lung Resection: Comment. Anesthesiology. 2023 06 01; 138(6):664-665. Hoftman N, Umar S. PMID: 36787157.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    7. Thoracic Spinal Cord Neuroinflammation as a Novel Therapeutic Target in Pulmonary Hypertension. Hypertension. 2023 06; 80(6):1297-1310. Razee A, Banerjee S, Hong J, Magaki S, Fishbein G, Ajijola OA, Umar S. PMID: 37092338; PMCID: PMC10192067.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimals
    8. Tm4sf1-marked Endothelial Subpopulation Is Dysregulated in Pulmonary Arterial Hypertension. Am J Respir Cell Mol Biol. 2023 04; 68(4):381-394. Hong J, Wong B, Huynh C, Tang B, Ruffenach G, Li M, Umar S, Yang X, Eghbali M. PMID: 36252184; PMCID: PMC10112423.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimalsCells
    9. A novel negative pressure isolation device reduces aerosol exposure: A randomized controlled trial. Trends Anaesth Crit Care. 2023 Apr; 49:101229. Shin JS, Niu M, Chen H, Grogan T, Lee JS, Liew EC, Umar S, Shin DH, Zhu Y, Hoftman NN. PMID: 38621006; PMCID: PMC9986117.
      View in: PubMed   Mentions:
    10. Electrical Remodeling in Right Ventricular Failure Due to Pulmonary Hypertension: Unraveling Novel Therapeutic Targets. Int J Mol Sci. 2023 Feb 27; 24(5). Park JF, Liang J, Umar S. PMID: 36902065; PMCID: PMC10003421.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    11. Intralipid® improves left ventricular function in rats with lipopolysaccharide-induced endotoxaemia by a Src-STAT3-mediated mechanism. Br J Anaesth. 2023 02; 130(2):e183-e187. Banerjee S, Zargari M, Medzikovic L, Russino H, Mikhael M, Koons N, Grogan T, Rahman S, Eghbali M, Umar S. PMID: 36462942; PMCID: PMC10170391.
      View in: PubMed   Mentions:    Fields:    Translation:Animals
    12. Bmpr2 mutant mice are an inadequate model for studying iron deficiency in pulmonary hypertension. Pulm Circ. 2022 Oct; 12(4):e12151. Zhang V, Ganz T, Nemeth E, Umar S, Kim A. PMID: 36568690; PMCID: PMC9768458.
      View in: PubMed   Mentions: 2  
    13. Comparative analysis of right ventricular metabolic reprogramming in pre-clinical rat models of severe pulmonary hypertension-induced right ventricular failure. Front Cardiovasc Med. 2022; 9:935423. Banerjee S, Hong J, Umar S. PMID: 36158812; PMCID: PMC9500217.
      View in: PubMed   Mentions: 2  
    14. Intralipid fails to rescue bupivacaine-induced cardiotoxicity in late-pregnant rats. Front Med (Lausanne). 2022; 9:899036. Sherman C, Koons N, Zargari M, Cha C, Hirsch J, Hong R, Eghbali M, Umar S. PMID: 36035396; PMCID: PMC9411664.
      View in: PubMed   Mentions:
    15. Y-Chromosome Gene, Uty, Protects Against Pulmonary Hypertension by Reducing Proinflammatory Chemokines. Am J Respir Crit Care Med. 2022 07 15; 206(2):186-196. Cunningham CM, Li M, Ruffenach G, Doshi M, Aryan L, Hong J, Park J, Hrncir H, Medzikovic L, Umar S, Arnold AP, Eghbali M. PMID: 35504005; PMCID: PMC9887415.
      View in: PubMed   Mentions: 21     Fields:    Translation:HumansAnimalsCells
    16. Response by Park et al to Letter Regarding Article, "Transcriptomic Analysis of Right Ventricular Remodeling in Two Rat Models of Pulmonary Hypertension: Identification and Validation of Epithelial-to-Mesenchymal Transition in Human Right Ventricular Failure". Circ Heart Fail. 2022 07; 15(7):e008632. Park J, Banerjee S, Hong J, Umar S. PMID: 35766030; PMCID: PMC9348824.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    17. Needlestick injuries among anesthesia providers from a large US academic center: A 10-year retrospective analysis. J Clin Anesth. 2022 09; 80:110885. Borna R, Rahimian R, Natalie Koons BS, Grogan TR, Umar S, Turner J. PMID: 35644082.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    18. Recent advancements in pulmonary arterial hypertension and right heart failure research: overview of selected abstracts from ATS2020 and emerging COVID-19 research. Pulm Circ. 2021 Jul-Sep; 11(3):20458940211037274. Potus F, Frump AL, Umar S, R Vanderpool R, Al Ghouleh I, Lai YC. PMID: 34434543; PMCID: PMC8381443.
      View in: PubMed   Mentions: 3  
    19. Single-Cell Study of Two Rat Models of Pulmonary Arterial Hypertension Reveals Connections to Human Pathobiology and Drug Repositioning. Am J Respir Crit Care Med. 2021 04 15; 203(8):1006-1022. Hong J, Arneson D, Umar S, Ruffenach G, Cunningham CM, Ahn IS, Diamante G, Bhetraratana M, Park JF, Said E, Huynh C, Le T, Medzikovic L, Humbert M, Soubrier F, Montani D, Girerd B, Trégouët DA, Channick R, Saggar R, Eghbali M, Yang X. PMID: 33021809; PMCID: PMC8048757.
      View in: PubMed   Mentions: 32     Fields:    Translation:HumansAnimalsCells
    20. Transcriptomic Analysis of Right Ventricular Remodeling in Two Rat Models of Pulmonary Hypertension: Identification and Validation of Epithelial-to-Mesenchymal Transition in Human Right Ventricular Failure. Circ Heart Fail. 2021 02; 14(2):e007058. Park JF, Clark VR, Banerjee S, Hong J, Razee A, Williams T, Fishbein G, Saddic L, Umar S. PMID: 33541093; PMCID: PMC7887079.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansAnimalsCells
    21. A Novel Negative Pressure Isolation Device for Aerosol Transmissible COVID-19. Anesth Analg. 2020 09; 131(3):664-668. Seger CD, Wang L, Dong X, Tebon P, Kwon S, Liew EC, Marijic J, Umar S, Hoftman NN. PMID: 32541251; PMCID: PMC7302060.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCellsPHPublic Health
    22. Oral 15-Hydroxyeicosatetraenoic Acid Induces Pulmonary Hypertension in Mice by Triggering T Cell-Dependent Endothelial Cell Apoptosis. Hypertension. 2020 09; 76(3):985-996. Ruffenach G, O'Connor E, Vaillancourt M, Hong J, Cao N, Sarji S, Moazeni S, Papesh J, Grijalva V, Cunningham CM, Shu L, Chattopadhyay A, Tiwari S, Mercier O, Perros F, Umar S, Yang X, Gomes AV, Fogelman AM, Reddy ST, Eghbali M. PMID: 32713273; PMCID: PMC8008496.
      View in: PubMed   Mentions: 11     Fields:    Translation:AnimalsCells
    23. Angiotensin Converting Enzyme Inhibitor and Angiotensin II Receptor Blocker Use Among Outpatients Diagnosed With COVID-19. Am J Cardiol. 2020 10 01; 132:150-157. Bae DJ, Tehrani DM, Rabadia SV, Frost M, Parikh RV, Calfon-Press M, Aksoy O, Umar S, Ardehali R, Rabbani A, Bokhoor P, Nsair A, Currier J, Tobis J, Fonarow GC, Dave R, Rafique AM. PMID: 32819683; PMCID: PMC7354276.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansCellsPHPublic Health
    24. In the eye of the storm: the right ventricle in COVID-19. Pulm Circ. 2020 Jul-Sep; 10(3):2045894020936660. Park JF, Banerjee S, Umar S. PMID: 32655856; PMCID: PMC7333504.
      View in: PubMed   Mentions: 41  
    25. The Role of Estrogen Receptors in Cardiovascular Disease. Int J Mol Sci. 2020 Jun 17; 21(12). Aryan L, Younessi D, Zargari M, Banerjee S, Agopian J, Rahman S, Borna R, Ruffenach G, Umar S, Eghbali M. PMID: 32560398; PMCID: PMC7352426.
      View in: PubMed   Mentions: 57     Fields:    Translation:HumansAnimalsCells
    26. Medical education in the COVID-19 era: Impact on anesthesiology trainees. J Clin Anesth. 2020 11; 66:109949. Anwar A, Seger C, Tollefson A, Diachun CAB, Tanaka P, Umar S. PMID: 32504968; PMCID: PMC7262539.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansPHPublic Health
    27. Editorial Commentary: Pulmonary Artery Denervation for Pulmonary Hypertension: Recent Updates and Future Perspectives. Trends Cardiovasc Med. 2021 05; 31(4):261-263. Razee A, Umar S. PMID: 32434044.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    28. Pregnancy-associated cardiac dysfunction and the regulatory role of microRNAs. Biol Sex Differ. 2020 04 06; 11(1):14. Aryan L, Medzikovic L, Umar S, Eghbali M. PMID: 32252821; PMCID: PMC7137306.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansAnimals
    29. Involvement of Low-Density Lipoprotein Receptor in the Pathogenesis of Pulmonary Hypertension. J Am Heart Assoc. 2020 01 21; 9(2):e012063. Umar S, Ruffenach G, Moazeni S, Vaillancourt M, Hong J, Cunningham C, Cao N, Navab S, Sarji S, Li M, Lee L, Fishbein G, Ardehali A, Navab M, Reddy ST, Eghbali M. PMID: 31914876; PMCID: PMC7033825.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansAnimalsCells
    30. Oxidative Stress and Its Implications in the Right Ventricular Remodeling Secondary to Pulmonary Hypertension. Front Physiol. 2019; 10:1233. Mikhael M, Makar C, Wissa A, Le T, Eghbali M, Umar S. PMID: 31607955; PMCID: PMC6769067.
      View in: PubMed   Mentions: 14  
    31. Experimental Pulmonary Hypertension Is Associated With Neuroinflammation in the Spinal Cord. Front Physiol. 2019; 10:1186. Vaillancourt M, Chia P, Medzikovic L, Cao N, Ruffenach G, Younessi D, Umar S. PMID: 31616310; PMCID: PMC6764190.
      View in: PubMed   Mentions: 5  
    32. Histological hallmarks and role of Slug/PIP axis in pulmonary hypertension secondary to pulmonary fibrosis. EMBO Mol Med. 2019 09; 11(9):e10061. Ruffenach G, Umar S, Vaillancourt M, Hong J, Cao N, Sarji S, Moazeni S, Cunningham CM, Ardehali A, Reddy ST, Saggar R, Fishbein G, Eghbali M. PMID: 31468711; PMCID: PMC6728601.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansAnimalsCells
    33. Pulmonary artery denervation: a novel treatment modality for pulmonary hypertension. J Thorac Dis. 2019 Apr; 11(4):1094-1096. Le T, Makar C, Morway P, Hoftman N, Umar S. PMID: 31179049; PMCID: PMC6531721.
      View in: PubMed   Mentions: 4  
    34. In Reply. Anesthesiology. 2019 03; 130(3):519-521. Umar S, Eghbali M. PMID: 30762648.
      View in: PubMed   Mentions:    Fields:    
    35. Estrogen rescues heart failure through estrogen receptor Beta activation. Biol Sex Differ. 2018 10 30; 9(1):48. Iorga A, Umar S, Ruffenach G, Aryan L, Li J, Sharma S, Motayagheni N, Nadadur RD, Bopassa JC, Eghbali M. PMID: 30376877; PMCID: PMC6208048.
      View in: PubMed   Mentions: 29     Fields:    Translation:AnimalsCells
    36. Free Fatty Acid Receptor G-protein-coupled Receptor 40 Mediates Lipid Emulsion-induced Cardioprotection. Anesthesiology. 2018 07; 129(1):154-162. Umar S, Li J, Hannabass K, Vaillancourt M, Cunningham CM, Moazeni S, Mahajan A, Eghbali M. PMID: 29620570; PMCID: PMC6084795.
      View in: PubMed   Mentions: 7     Fields:    Translation:AnimalsCells
    37. The Y Chromosome Plays a Protective Role in Experimental Hypoxic Pulmonary Hypertension. Am J Respir Crit Care Med. 2018 04 01; 197(7):952-955. Umar S, Cunningham CM, Itoh Y, Moazeni S, Vaillancourt M, Sarji S, Centala A, Arnold AP, Eghbali M. PMID: 28934553; PMCID: PMC6020406.
      View in: PubMed   Mentions: 38     Fields:    Translation:AnimalsCells
    38. Effects of teriparatide on morphology of aortic calcification in aged hyperlipidemic mice. Am J Physiol Heart Circ Physiol. 2018 06 01; 314(6):H1203-H1213. Hsu JJ, Lu J, Umar S, Lee JT, Kulkarni RP, Ding Y, Chang CC, Hsiai TK, Hokugo A, Gkouveris I, Tetradis S, Nishimura I, Demer LL, Tintut Y. PMID: 29451816; PMCID: PMC6032086.
      View in: PubMed   Mentions: 16     Fields:    Translation:Animals
    39. Autonomic nervous system involvement in pulmonary arterial hypertension. Respir Res. 2017 12 04; 18(1):201. Vaillancourt M, Chia P, Sarji S, Nguyen J, Hoftman N, Ruffenach G, Eghbali M, Mahajan A, Umar S. PMID: 29202826; PMCID: PMC5715548.
      View in: PubMed   Mentions: 50     Fields:    Translation:HumansAnimals
    40. The protective role of estrogen and estrogen receptors in cardiovascular disease and the controversial use of estrogen therapy. Biol Sex Differ. 2017 10 24; 8(1):33. Iorga A, Cunningham CM, Moazeni S, Ruffenach G, Umar S, Eghbali M. PMID: 29065927; PMCID: PMC5655818.
      View in: PubMed   Mentions: 303     Fields:    Translation:HumansAnimals
    41. Severe pulmonary hypertension in aging female apolipoprotein E-deficient mice is rescued by estrogen replacement therapy. Biol Sex Differ. 2017; 8:9. Umar S, Partow-Navid R, Ruffenach G, Iorga A, Moazeni S, Eghbali M. PMID: 28344760; PMCID: PMC5360087.
      View in: PubMed   Mentions: 7     Fields:    Translation:Animals
    42. Intralipid protects the heart in late pregnancy against ischemia/reperfusion injury via Caveolin2/STAT3/GSK-3β pathway. J Mol Cell Cardiol. 2017 01; 102:108-116. Li J, Ruffenach G, Kararigas G, Cunningham CM, Motayagheni N, Barakai N, Umar S, Regitz-Zagrosek V, Eghbali M. PMID: 27847332; PMCID: PMC5831539.
      View in: PubMed   Mentions: 17     Fields:    Translation:AnimalsCells
    43. Role of oxidized lipids in pulmonary arterial hypertension. Pulm Circ. 2016 Sep; 6(3):261-73. Sharma S, Ruffenach G, Umar S, Motayagheni N, Reddy ST, Eghbali M. PMID: 27683603; PMCID: PMC5019079.
      View in: PubMed   Mentions: 22  
    44. Novel biomarkers for pulmonary arterial hypertension. Respir Res. 2016 07 20; 17(1):88. Anwar A, Ruffenach G, Mahajan A, Eghbali M, Umar S. PMID: 27439993; PMCID: PMC4955255.
      View in: PubMed   Mentions: 25     Fields:    Translation:HumansAnimals
    45. Rescue of Pressure Overload-Induced Heart Failure by Estrogen Therapy. J Am Heart Assoc. 2016 Jan 22; 5(1). Iorga A, Li J, Sharma S, Umar S, Bopassa JC, Nadadur RD, Centala A, Ren S, Saito T, Toro L, Wang Y, Stefani E, Eghbali M. PMID: 26802104; PMCID: PMC4859364.
      View in: PubMed   Mentions: 36     Fields:    Translation:AnimalsCells
    46. Role of miR206 in genistein-induced rescue of pulmonary hypertension in monocrotaline model. J Appl Physiol (1985). 2015 Dec 15; 119(12):1374-82. Sharma S, Umar S, Centala A, Eghbali M. PMID: 26472874; PMCID: PMC4683348.
      View in: PubMed   Mentions: 7     Fields:    Translation:Animals
    47. Involvement of Opioid Receptors in the Lipid Rescue of Bupivacaine-Induced Cardiotoxicity. Anesth Analg. 2015 Aug; 121(2):340-7. Partownavid P, Sharma S, Li J, Umar S, Rahman S, Eghbali M. PMID: 25993392.
      View in: PubMed   Mentions: 8     Fields:    Translation:AnimalsCells
    48. Stem and progenitor cell therapy for pulmonary arterial hypertension: effects on the right ventricle (2013 Grover Conference Series). Pulm Circ. 2015 Mar; 5(1):73-80. van der Laarse A, Cobbaert CM, Umar S. PMID: 25992272; PMCID: PMC4405720.
      View in: PubMed   Mentions: 6  
    49. Apolipoprotein A-I mimetic peptide 4F rescues pulmonary hypertension by inducing microRNA-193-3p. Circulation. 2014 Aug 26; 130(9):776-85. Sharma S, Umar S, Potus F, Iorga A, Wong G, Meriwether D, Breuils-Bonnet S, Mai D, Navab K, Ross D, Navab M, Provencher S, Fogelman AM, Bonnet S, Reddy ST, Eghbali M. PMID: 24963038; PMCID: PMC4194270.
      View in: PubMed   Mentions: 49     Fields:    Translation:HumansAnimalsCells
    50. The number of X chromosomes influences protection from cardiac ischaemia/reperfusion injury in mice: one X is better than two. Cardiovasc Res. 2014 Jun 01; 102(3):375-84. Li J, Chen X, McClusky R, Ruiz-Sundstrom M, Itoh Y, Umar S, Arnold AP, Eghbali M. PMID: 24654234; PMCID: PMC4030514.
      View in: PubMed   Mentions: 55     Fields:    Translation:AnimalsCells
    51. Depolarization-induced automaticity in rat ventricular cardiomyocytes is based on the gating properties of L-type calcium and slow Kv channels. Eur Biophys J. 2013 Apr; 42(4):241-55. Ypey DL, van Meerwijk WP, Umar S, Pijnappels DA, Schalij MJ, van der Laarse A. PMID: 23089919.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    52. Intralipid, a clinically safe compound, protects the heart against ischemia-reperfusion injury more efficiently than cyclosporine-A. Anesthesiology. 2012 Oct; 117(4):836-46. Li J, Iorga A, Sharma S, Youn JY, Partow-Navid R, Umar S, Cai H, Rahman S, Eghbali M. PMID: 22814384; PMCID: PMC3769111.
      View in: PubMed   Mentions: 37     Fields:    Translation:AnimalsCells
    53. Cardiac structural and hemodynamic changes associated with physiological heart hypertrophy of pregnancy are reversed postpartum. J Appl Physiol (1985). 2012 Oct 15; 113(8):1253-9. Umar S, Nadadur R, Iorga A, Amjedi M, Matori H, Eghbali M. PMID: 22923507; PMCID: PMC3472485.
      View in: PubMed   Mentions: 33     Fields:    Translation:AnimalsCells
    54. Fatty-acid oxidation and calcium homeostasis are involved in the rescue of bupivacaine-induced cardiotoxicity by lipid emulsion in rats. Crit Care Med. 2012 Aug; 40(8):2431-7. Partownavid P, Umar S, Li J, Rahman S, Eghbali M. PMID: 22647409; PMCID: PMC3401289.
      View in: PubMed   Mentions: 38     Fields:    Translation:AnimalsCells
    55. New frontiers in heart hypertrophy during pregnancy. Am J Cardiovasc Dis. 2012; 2(3):192-207. Li J, Umar S, Amjedi M, Iorga A, Sharma S, Nadadur RD, Regitz-Zagrosek V, Eghbali M. PMID: 22937489; PMCID: PMC3427979.
      View in: PubMed   Mentions: 36  
    56. Genistein, a soy phytoestrogen, reverses severe pulmonary hypertension and prevents right heart failure in rats. Hypertension. 2012 Aug; 60(2):425-30. Matori H, Umar S, Nadadur RD, Sharma S, Partow-Navid R, Afkhami M, Amjedi M, Eghbali M. PMID: 22753213; PMCID: PMC4252152.
      View in: PubMed   Mentions: 37     Fields:    Translation:HumansAnimalsCells
    57. Cardiac vulnerability to ischemia/reperfusion injury drastically increases in late pregnancy. Basic Res Cardiol. 2012 Jul; 107(4):271. Li J, Umar S, Iorga A, Youn JY, Wang Y, Regitz-Zagrosek V, Cai H, Eghbali M. PMID: 22648276; PMCID: PMC3769136.
      View in: PubMed   Mentions: 16     Fields:    Translation:AnimalsCells
    58. Reverse right ventricular structural and extracellular matrix remodeling by estrogen in severe pulmonary hypertension. J Appl Physiol (1985). 2012 Jul; 113(1):149-58. Nadadur RD, Umar S, Wong G, Eghbali M, Iorga A, Matori H, Partow-Navid R, Eghbali M. PMID: 22628376; PMCID: PMC3404831.
      View in: PubMed   Mentions: 36     Fields:    Translation:AnimalsCells
    59. Estrogen paradox in pulmonary hypertension: current controversies and future perspectives. Am J Respir Crit Care Med. 2012 Jul 15; 186(2):125-31. Umar S, Rabinovitch M, Eghbali M. PMID: 22561960; PMCID: PMC3406082.
      View in: PubMed   Mentions: 37     Fields:    Translation:HumansAnimals
    60. Spontaneous ventricular fibrillation in right ventricular failure secondary to chronic pulmonary hypertension. Circ Arrhythm Electrophysiol. 2012 Feb; 5(1):181-90. Umar S, Lee JH, de Lange E, Iorga A, Partow-Navid R, Bapat A, van der Laarse A, Saggar R, Saggar R, Ypey DL, Karagueuzian HS, Eghbali M. PMID: 22199010; PMCID: PMC3319685.
      View in: PubMed   Mentions: 34     Fields:    Translation:Animals
    61. Phosphorylation of GSK-3β mediates intralipid-induced cardioprotection against ischemia/reperfusion injury. Anesthesiology. 2011 Aug; 115(2):242-53. Rahman S, Li J, Bopassa JC, Umar S, Iorga A, Partownavid P, Eghbali M. PMID: 21691195; PMCID: PMC3322241.
      View in: PubMed   Mentions: 62     Fields:    Translation:AnimalsCells
    62. Intralipid prevents and rescues fatal pulmonary arterial hypertension and right ventricular failure in rats. Hypertension. 2011 Sep; 58(3):512-8. Umar S, Nadadur RD, Li J, Maltese F, Partownavid P, van der Laarse A, Eghbali M. PMID: 21747043; PMCID: PMC3339261.
      View in: PubMed   Mentions: 11     Fields:    Translation:Animals
    63. Estrogen rescues preexisting severe pulmonary hypertension in rats. Am J Respir Crit Care Med. 2011 Sep 15; 184(6):715-23. Umar S, Iorga A, Matori H, Nadadur RD, Li J, Maltese F, van der Laarse A, Eghbali M. PMID: 21700911; PMCID: PMC3208600.
      View in: PubMed   Mentions: 79     Fields:    Translation:Animals
    64. Integrin stimulation favors uptake of macromolecules by cardiomyocytes in vitro. Cell Physiol Biochem. 2010; 26(6):999-1010. Swildens J, de Vries AA, Li Z, Umar S, Atsma DE, Schalij MJ, van der Laarse A. PMID: 21220931.
      View in: PubMed   Mentions: 6     Fields:    Translation:AnimalsCells
    65. Allogenic stem cell therapy improves right ventricular function by improving lung pathology in rats with pulmonary hypertension. Am J Physiol Heart Circ Physiol. 2009 Nov; 297(5):H1606-16. Umar S, de Visser YP, Steendijk P, Schutte CI, Laghmani el H, Wagenaar GT, Bax WH, Mantikou E, Pijnappels DA, Atsma DE, Schalij MJ, van der Wall EE, van der Laarse A. PMID: 19783775.
      View in: PubMed   Mentions: 51     Fields:    Translation:AnimalsCells
    66. Nitric oxide and nitric oxide synthase isoforms in the normal, hypertrophic, and failing heart. Mol Cell Biochem. 2010 Jan; 333(1-2):191-201. Umar S, van der Laarse A. PMID: 19618122.
      View in: PubMed   Mentions: 74     Fields:    
    67. Myocardial collagen metabolism in failing hearts before and during cardiac resynchronization therapy. Eur J Heart Fail. 2008 Sep; 10(9):878-83. Umar S, Bax JJ, Klok M, van Bommel RJ, Hessel MH, den Adel B, Bleeker GB, Henneman MM, Atsma DE, van der Wall EE, Schalij MJ, van der Laarse A. PMID: 18768351.
      View in: PubMed   Mentions: 11     Fields:    Translation:Humans
    68. Activation of signaling molecules and matrix metalloproteinases in right ventricular myocardium of rats with pulmonary hypertension. Pathol Res Pract. 2007; 203(12):863-72. Umar S, Hessel M, Steendijk P, Bax W, Schutte C, Schalij M, van der Wall E, Atsma D, van der Laarse A. PMID: 17913382.
      View in: PubMed   Mentions: 17     Fields:    Translation:AnimalsCells
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