Yin Tintut

Title(s)Adjunct Professor, Medicine
SchoolMedicine
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    Other Positions
    Title(s)Adjunct Professor, Orthopaedic Surgery

    Title(s)Adjunct Professor, Physiology


    Collapse Research 
    Collapse Research Activities and Funding
    Role of intermittent activation of parathyroid hormone receptor in exercise-induced vascular calcification
    NIH R01HL151391Jan 1, 2021 - Dec 31, 2024
    Role: Co-Principal Investigator
    Serotonin receptor contribution to inflammation-induced calcific aortic valve disease
    NIH R01HL137647Apr 1, 2019 - Mar 31, 2023
    Role: Co-Principal Investigator
    Does aging transform calcific vasculopathy into a plaque stabilizing process?
    NIH R21AG061586Jan 15, 2019 - Nov 30, 2021
    Role: Co-Principal Investigator
    Mechanisms of intermittent parathyroid hormone effects on calcific aortic disease
    NIH R01HL121019Mar 15, 2015 - Feb 28, 2019
    Role: Co-Principal Investigator
    Role of Inhibitory SMADs in Calcific Aortic Valve Disease
    NIH R01HL114709Aug 23, 2012 - Jun 30, 2017
    Role: Co-Principal Investigator
    Role of Lymphatic Clearance in Lipid-Induced Calcific Vasculopathy and Bone Loss
    NIH R21HL109628Aug 1, 2011 - Jun 30, 2014
    Role: Co-Principal Investigator
    Regulation of PTH-induced Osteoanabolism by Inflammatory Lipids
    NIH R01DK081346May 8, 2009 - Mar 31, 2015
    Role: Principal Investigator
    REGULATION OF PTH-INDUCED BONE ANABOLISM BY INFLAMMATORY LIPIDS
    NIH R21DK076009Aug 17, 2006 - Jul 31, 2009
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Collagen VIII in vascular diseases. Matrix Biol. 2024 Nov; 133:64-76. Li Q, Tintut Y, Demer LL, Vazquez-Padron RI, Bendeck MP, Hsu JJ. PMID: 39154854; PMCID: PMC11473120.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    2. Complex actions of sodium glucose transporter-2 inhibitors on lipids, calcific atherosclerosis, and bone density. Curr Opin Lipidol. 2024 Oct 01; 35(5):253-257. Pradhan S, Kalanski S, Tintut Y, Demer LL. PMID: 39052539.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimals
    3. Effects of Empagliflozin on Vascular and Skeletal Mineralization in Hyperlipidemic Mice. Vascul Pharmacol. 2024 Jun; 155:107376. Kalanski S, Pradhan S, Hon A, Xia Y, Safvati N, Rivera JC, Lu M, Demer LL, Tintut Y. PMID: 38692418.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    4. Effects of LP533401 on vascular and bone calcification in hyperlipidemic mice. Biochem Biophys Res Commun. 2024 05 28; 710:149854. Pradhan S, Hon A, Xia Y, Kalanski S, Safvati N, Lu M, Demer LL, Tintut Y. PMID: 38581947.
      View in: PubMed   Mentions:    Fields:    Translation:Animals
    5. Effects of activity levels on aortic calcification in hyperlipidemic mice as measured by microPETmicroCT. Atherosclerosis. 2023 09; 380:117198. Hon A, Hsu JJ, Zambrano A, Xia Y, Lu M, Echeverri D, Kalanski S, Umar S, Demer LL, Tintut Y. PMID: 37579593; PMCID: PMC11146201.
      View in: PubMed   Mentions:    Fields:    Translation:Animals
    6. Potential mechanisms linking high-volume exercise with coronary artery calcification. Heart. 2023 07 12; 109(15):1139-1145. Zambrano A, Tintut Y, Demer LL, Hsu JJ. PMID: 36702539; PMCID: PMC10356745.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    7. A Potential New Link Between Inflammation and Vascular Calcification. J Am Heart Assoc. 2023 01 03; 12(1):e028358. Cai X, Tintut Y, Demer LL. PMID: 36537336; PMCID: PMC9973574.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCells
    8. Regulation of cardiovascular calcification by lipids and lipoproteins. Curr Opin Lipidol. 2022 10 01; 33(5):289-294. Hsu JJ, Tintut Y, Demer LL. PMID: 35979985; PMCID: PMC9474571.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    9. Microarchitectural Changes of Cardiovascular Calcification in Response to In Vivo Interventions Using Deep-Learning Segmentation and Computed Tomography Radiomics. Arterioscler Thromb Vasc Biol. 2022 08; 42(8):e228-e241. Patel NR, Setya K, Pradhan S, Lu M, Demer LL, Tintut Y. PMID: 35708025; PMCID: PMC9339530.
      View in: PubMed   Mentions: 3     Fields:    Translation:Animals
    10. Biomolecules Orchestrating Cardiovascular Calcification. Biomolecules. 2021 10 07; 11(10). Tintut Y, Honda HM, Demer LL. PMID: 34680115; PMCID: PMC8533507.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimals
    11. Lipids and cardiovascular calcification: contributions to plaque vulnerability. Curr Opin Lipidol. 2021 10 01; 32(5):308-314. Hsu JJ, Tintut Y, Demer LL. PMID: 34320564; PMCID: PMC8416796.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimals
    12. The Mechanobiology of Endothelial-to-Mesenchymal Transition in Cardiovascular Disease. Front Physiol. 2021; 12:734215. Islam S, Boström KI, Di Carlo D, Simmons CA, Tintut Y, Yao Y, Hsu JJ. PMID: 34566697; PMCID: PMC8458763.
      View in: PubMed   Mentions: 18  
    13. A biomarker for vascular calcification: shedding light on an unfinished story? Cardiovasc Res. 2021 07 07; 117(8):1809-1810. Hsu JJ, Tintut Y, Demer LL. PMID: 33751037; PMCID: PMC8262638.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    14. Hearts of Stone: Calcific Aortic Stenosis and Antiresorptive Agents for Osteoporosis. Circulation. 2021 06 22; 143(25):2428-2430. Demer LL, Tintut Y. PMID: 34152795; PMCID: PMC8221117.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    15. Potential impact of the steroid hormone, vitamin D, on the vasculature. Am Heart J. 2021 09; 239:147-153. Tintut Y, Demer LL. PMID: 34051171; PMCID: PMC8425762.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    16. Statin Effects on Vascular Calcification: Microarchitectural Changes in Aortic Calcium Deposits in Aged Hyperlipidemic Mice. Arterioscler Thromb Vasc Biol. 2021 04; 41(4):e185-e192. Xian JZ, Lu M, Fong F, Qiao R, Patel NR, Abeydeera D, Iriana S, Demer LL, Tintut Y. PMID: 33472400; PMCID: PMC7990692.
      View in: PubMed   Mentions: 15     Fields:    Translation:Animals
    17. Serotonin receptor type 2B activation augments TNF-α-induced matrix mineralization in murine valvular interstitial cells. J Cell Biochem. 2021 02; 122(2):249-258. Fong F, Xian J, Demer LL, Tintut Y. PMID: 32901992; PMCID: PMC7770058.
      View in: PubMed   Mentions: 7     Fields:    Translation:AnimalsCells
    18. Changes in microarchitecture of atherosclerotic calcification assessed by 18F-NaF PET and CT after a progressive exercise regimen in hyperlipidemic mice. J Nucl Cardiol. 2021 10; 28(5):2207-2214. Hsu JJ, Fong F, Patel R, Qiao R, Lo K, Soundia A, Chang CC, Le V, Tseng CH, Demer LL, Tintut Y. PMID: 31897996; PMCID: PMC7329622.
      View in: PubMed   Mentions: 18     Fields:    Translation:Animals
    19. Regulation of calcific vascular and valvular disease by nuclear receptors. Curr Opin Lipidol. 2019 10; 30(5):357-363. Sallam T, Tintut Y, Demer LL. PMID: 31369409; PMCID: PMC6719701.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    20. Interactive and Multifactorial Mechanisms of Calcific Vascular and Valvular Disease. Trends Endocrinol Metab. 2019 09; 30(9):646-657. Demer LL, Tintut Y. PMID: 31279666; PMCID: PMC6708492.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansAnimals
    21. Contractile and hemodynamic forces coordinate Notch1b-mediated outflow tract valve formation. JCI Insight. 2019 04 11; 5. Hsu JJ, Vedula V, Baek KI, Chen C, Chen J, Chou MI, Lam J, Subhedar S, Wang J, Ding Y, Chang CC, Lee J, Demer LL, Tintut Y, Marsden AL, Hsiai TK. PMID: 30973827; PMCID: PMC6542601.
      View in: PubMed   Mentions: 23     Fields:    Translation:AnimalsCells
    22. Lipoproteins in Cardiovascular Calcification: Potential Targets and Challenges. Front Cardiovasc Med. 2018; 5:172. Tintut Y, Hsu JJ, Demer LL. PMID: 30533416; PMCID: PMC6265366.
      View in: PubMed   Mentions: 18  
    23. Multiscale light-sheet for rapid imaging of cardiopulmonary system. JCI Insight. 2018 08 23; 3(16). Ding Y, Ma J, Langenbacher AD, Baek KI, Lee J, Chang CC, Hsu JJ, Kulkarni RP, Belperio J, Shi W, Ranjbarvaziri S, Ardehali R, Tintut Y, Demer LL, Chen JN, Fei P, Packard RRS, Hsiai TK. PMID: 30135307; PMCID: PMC6141183.
      View in: PubMed   Mentions: 23     Fields:    Translation:Animals
    24. Steroid Hormone Vitamin D: Implications for Cardiovascular Disease. Circ Res. 2018 05 25; 122(11):1576-1585. Demer LL, Hsu JJ, Tintut Y. PMID: 29798901; PMCID: PMC6122607.
      View in: PubMed   Mentions: 39     Fields:    Translation:HumansCells
    25. Effects of teriparatide on morphology of aortic calcification in aged hyperlipidemic mice. Am J Physiol Heart Circ Physiol. 2018 06 01; 314(6):H1203-H1213. Hsu JJ, Lu J, Umar S, Lee JT, Kulkarni RP, Ding Y, Chang CC, Hsiai TK, Hokugo A, Gkouveris I, Tetradis S, Nishimura I, Demer LL, Tintut Y. PMID: 29451816; PMCID: PMC6032086.
      View in: PubMed   Mentions: 16     Fields:    Translation:Animals
    26. Rigor and Reproducibility in Analysis of Vascular Calcification. Circ Res. 2017 04 14; 120(8):1240-1242. Demer LL, Tintut Y, Nguyen KL, Hsiai T, Lee JT. PMID: 28408452; PMCID: PMC5407390.
      View in: PubMed   Mentions: 12     Fields:    Translation:Humans
    27. Activating transcription factor-4 promotes mineralization in vascular smooth muscle cells. JCI Insight. 2016 11 03; 1(18):e88646. Masuda M, Miyazaki-Anzai S, Keenan AL, Shiozaki Y, Okamura K, Chick WS, Williams K, Zhao X, Rahman SM, Tintut Y, Adams CM, Miyazaki M. PMID: 27812542; PMCID: PMC5085604.
      View in: PubMed   Mentions: 22     Fields:    Translation:HumansAnimalsCells
    28. Cell-matrix mechanics and pattern formation in inflammatory cardiovascular calcification. Heart. 2016 11 01; 102(21):1710-1715. Hsu JJ, Lim J, Tintut Y, Demer LL. PMID: 27406839; PMCID: PMC5069068.
      View in: PubMed   Mentions: 23     Fields:    Translation:HumansAnimalsCells
    29. COMP-lex Mechanics: Matricrine Signaling. Circ Res. 2016 07 08; 119(2):184-6. Tintut Y, Demer LL. PMID: 27390328; PMCID: PMC4940136.
      View in: PubMed   Mentions: 1     Fields:    Translation:Cells
    30. Reply: Evolutionary approach sheds light on the significance of vascular calcification. Trends Cardiovasc Med. 2017 01; 27(1):72. Demer LL, Tintut Y. PMID: 27499040; PMCID: PMC5167644.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    31. Inflammation Drives Retraction, Stiffening, and Nodule Formation via Cytoskeletal Machinery in a Three-Dimensional Culture Model of Aortic Stenosis. Am J Pathol. 2016 09; 186(9):2378-89. Lim J, Ehsanipour A, Hsu JJ, Lu J, Pedego T, Wu A, Walthers CM, Demer LL, Seidlits SK, Tintut Y. PMID: 27392969; PMCID: PMC5012467.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansAnimalsCells
    32. Protective Role of Smad6 in Inflammation-Induced Valvular Cell Calcification. J Cell Biochem. 2015 Oct; 116(10):2354-64. Li X, Lim J, Lu J, Pedego TM, Demer L, Tintut Y. PMID: 25864564; PMCID: PMC5003537.
      View in: PubMed   Mentions: 23     Fields:    Translation:HumansAnimalsCells
    33. Exosomes: nanosized cellular messages. Circ Res. 2015 Apr 10; 116(8):1281-3. Tintut Y, Demer LL. PMID: 25858057; PMCID: PMC5127443.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCells
    34. The leading edge of vascular calcification. Trends Cardiovasc Med. 2015 May; 25(4):275-7. Demer LL, Tintut Y. PMID: 25572012; PMCID: PMC4414923.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    35. Hyperlipidemia affects multiscale structure and strength of murine femur. J Biomech. 2014 Jul 18; 47(10):2436-43. Ascenzi MG, Lutz A, Du X, Klimecky L, Kawas N, Hourany T, Jahng J, Chin J, Tintut Y, Nackenhors U, Keyak J. PMID: 24795172; PMCID: PMC4141538.
      View in: PubMed   Mentions: 8     Fields:    Translation:Animals
    36. Inflammatory, metabolic, and genetic mechanisms of vascular calcification. Arterioscler Thromb Vasc Biol. 2014 Apr; 34(4):715-23. Demer LL, Tintut Y. PMID: 24665125; PMCID: PMC3975044.
      View in: PubMed   Mentions: 133     Fields:    Translation:HumansAnimals
    37. FGF23 protein expression in coronary arteries is associated with impaired kidney function. Nephrol Dial Transplant. 2014 Aug; 29(8):1525-32. van Venrooij NA, Pereira RC, Tintut Y, Fishbein MC, Tumber N, Demer LL, Salusky IB, Wesseling-Perry K. PMID: 24459137; PMCID: PMC4118139.
      View in: PubMed   Mentions: 29     Fields:    Translation:Humans
    38. Roles of parathyroid hormone (PTH) receptor and reactive oxygen species in hyperlipidemia-induced PTH resistance in preosteoblasts. J Cell Biochem. 2014 Jan; 115(1):179-88. Li X, Garcia J, Lu J, Iriana S, Kalajzic I, Rowe D, Demer LL, Tintut Y. PMID: 24038594; PMCID: PMC3889484.
      View in: PubMed   Mentions: 6     Fields:    Translation:AnimalsCells
    39. The effects of hyperlipidemia on implant osseointegration in the mouse femur. J Oral Implantol. 2015 Apr; 41(2):e7-e11. Keuroghlian A, Barroso AD, Kirikian G, Bezouglaia O, Tintut Y, Tetradis S, Moy P, Pirih F, Aghaloo T. PMID: 24295508; PMCID: PMC4465368.
      View in: PubMed   Mentions: 19     Fields:    Translation:Animals
    40. Effects of bioactive lipids and lipoproteins on bone. Trends Endocrinol Metab. 2014 Feb; 25(2):53-9. Tintut Y, Demer LL. PMID: 24183940; PMCID: PMC3946677.
      View in: PubMed   Mentions: 35     Fields:    Translation:HumansAnimalsCells
    41. Role of paraoxonase-1 in bone anabolic effects of parathyroid hormone in hyperlipidemic mice. Biochem Biophys Res Commun. 2013 Feb 01; 431(1):19-24. Lu J, Cheng H, Atti E, Shih DM, Demer LL, Tintut Y. PMID: 23291186; PMCID: PMC3563775.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimalsCells
    42. Regulatory circuits controlling vascular cell calcification. Cell Mol Life Sci. 2013 Sep; 70(17):3187-97. Sallam T, Cheng H, Demer LL, Tintut Y. PMID: 23269436; PMCID: PMC3638052.
      View in: PubMed   Mentions: 13     Fields:    Translation:Humans
    43. Atmospheric ultrafine particles promote vascular calcification via the NF-κB signaling pathway. Am J Physiol Cell Physiol. 2013 Feb 15; 304(4):C362-9. Li R, Mittelstein D, Kam W, Pakbin P, Du Y, Tintut Y, Navab M, Sioutas C, Hsiai T. PMID: 23242187; PMCID: PMC3566535.
      View in: PubMed   Mentions: 19     Fields:    Translation:AnimalsCells
    44. Preferred mitotic orientation in pattern formation by vascular mesenchymal cells. Am J Physiol Heart Circ Physiol. 2012 Dec 15; 303(12):H1411-7. Wong MN, Nguyen TP, Chen TH, Hsu JJ, Zeng X, Saw A, Demer EM, Zhao X, Tintut Y, Demer LL. PMID: 23064835; PMCID: PMC3532532.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    45. Enhanced mineralization potential of vascular cells from SM22α-Rankl (tg) mice. Calcif Tissue Int. 2012 Dec; 91(6):379-86. Morony S, Sage AP, Corbin T, Lu J, Tintut Y, Demer LL. PMID: 23052229; PMCID: PMC3523707.
      View in: PubMed   Mentions: 7     Fields:    Translation:AnimalsCells
    46. Directing tissue morphogenesis via self-assembly of vascular mesenchymal cells. Biomaterials. 2012 Dec; 33(35):9019-26. Chen TH, Zhu X, Pan L, Zeng X, Garfinkel A, Tintut Y, Demer LL, Zhao X, Ho CM. PMID: 23010575; PMCID: PMC3466383.
      View in: PubMed   Mentions: 12     Fields:    Translation:AnimalsCells
    47. Focal high cell density generates a gradient of patterns in self-organizing vascular mesenchymal cells. J Vasc Res. 2012; 49(5):441-6. Cheng H, Reddy A, Sage A, Lu J, Garfinkel A, Tintut Y, Demer LL. PMID: 22797747; PMCID: PMC3478883.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    48. Patterns of periodic holes created by increased cell motility. Interface Focus. 2012 Aug 06; 2(4):457-64. Chen TH, Guo C, Zhao X, Yao Y, Boström KI, Wong MN, Tintut Y, Demer LL, Ho CM, Garfinkel A. PMID: 22649581; PMCID: PMC3363038.
      View in: PubMed   Mentions: 5  
    49. Adverse effects of hyperlipidemia on bone regeneration and strength. J Bone Miner Res. 2012 Feb; 27(2):309-18. Pirih F, Lu J, Ye F, Bezouglaia O, Atti E, Ascenzi MG, Tetradis S, Demer L, Aghaloo T, Tintut Y. PMID: 21987408; PMCID: PMC3274629.
      View in: PubMed   Mentions: 49     Fields:    Translation:Animals
    50. Left-right symmetry breaking in tissue morphogenesis via cytoskeletal mechanics. Circ Res. 2012 Feb 17; 110(4):551-9. Chen TH, Hsu JJ, Zhao X, Guo C, Wong MN, Huang Y, Li Z, Garfinkel A, Ho CM, Tintut Y, Demer LL. PMID: 22223355; PMCID: PMC3288887.
      View in: PubMed   Mentions: 46     Fields:    Translation:AnimalsCells
    51. A dynamic model of calcific nodule destabilization in response to monocyte- and oxidized lipid-induced matrix metalloproteinases. Am J Physiol Cell Physiol. 2012 Feb 15; 302(4):C658-65. Li R, Mittelstein D, Lee J, Fang K, Majumdar R, Tintut Y, Demer LL, Hsiai TK. PMID: 22031601; PMCID: PMC3287359.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansAnimalsCells
    52. Role of cellular cholesterol metabolism in vascular cell calcification. J Biol Chem. 2011 Sep 23; 286(38):33701-6. Geng Y, Hsu JJ, Lu J, Ting TC, Miyazaki M, Demer LL, Tintut Y. PMID: 21835914; PMCID: PMC3190941.
      View in: PubMed   Mentions: 19     Fields:    Translation:AnimalsCells
    53. The roles of lipid oxidation products and receptor activator of nuclear factor-κB signaling in atherosclerotic calcification. Circ Res. 2011 Jun 10; 108(12):1482-93. Demer L, Tintut Y. PMID: 21659652; PMCID: PMC3128471.
      View in: PubMed   Mentions: 28     Fields:    Translation:HumansAnimalsCells
    54. Hyperlipidemia induces resistance to PTH bone anabolism in mice via oxidized lipids. J Bone Miner Res. 2011 Jun; 26(6):1197-206. Sage AP, Lu J, Atti E, Tetradis S, Ascenzi MG, Adams DJ, Demer LL, Tintut Y. PMID: 21611962; PMCID: PMC3312754.
      View in: PubMed   Mentions: 38     Fields:    Translation:HumansAnimalsCells
    55. Increased lipogenesis and stearate accelerate vascular calcification in calcifying vascular cells. J Biol Chem. 2011 Jul 08; 286(27):23938-49. Ting TC, Miyazaki-Anzai S, Masuda M, Levi M, Demer LL, Tintut Y, Miyazaki M. PMID: 21596756; PMCID: PMC3129175.
      View in: PubMed   Mentions: 29     Fields:    Translation:AnimalsCells
    56. The hemosteoblast: friend or foe? Circ Res. 2011 Apr 29; 108(9):1038-9. Tintut Y, Demer L. PMID: 21527740; PMCID: PMC3099550.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    57. Runx2-upregulated receptor activator of nuclear factor κB ligand in calcifying smooth muscle cells promotes migration and osteoclastic differentiation of macrophages. Arterioscler Thromb Vasc Biol. 2011 Jun; 31(6):1387-96. Byon CH, Sun Y, Chen J, Yuan K, Mao X, Heath JM, Anderson PG, Tintut Y, Demer LL, Wang D, Chen Y. PMID: 21454810; PMCID: PMC3098301.
      View in: PubMed   Mentions: 88     Fields:    Translation:AnimalsCells
    58. Bone density and hyperlipidemia: the T-lymphocyte connection. J Bone Miner Res. 2010 Nov; 25(11):2460-9. Graham LS, Tintut Y, Parhami F, Kitchen CM, Ivanov Y, Tetradis S, Effros RB. PMID: 20533376; PMCID: PMC3179287.
      View in: PubMed   Mentions: 23     Fields:    Translation:AnimalsCells
    59. Hyperphosphatemia-induced nanocrystals upregulate the expression of bone morphogenetic protein-2 and osteopontin genes in mouse smooth muscle cells in vitro. Kidney Int. 2011 Feb; 79(4):414-22. Sage AP, Lu J, Tintut Y, Demer LL. PMID: 20944546; PMCID: PMC3198856.
      View in: PubMed   Mentions: 98     Fields:    Translation:AnimalsCells
    60. PKA-induced receptor activator of NF-kappaB ligand (RANKL) expression in vascular cells mediates osteoclastogenesis but not matrix calcification. J Biol Chem. 2010 Sep 24; 285(39):29925-31. Tseng W, Graham LS, Geng Y, Reddy A, Lu J, Effros RB, Demer L, Tintut Y. PMID: 20663885; PMCID: PMC2943298.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansAnimalsCells
    61. Regulatory mechanisms in vascular calcification. Nat Rev Cardiol. 2010 Sep; 7(9):528-36. Sage AP, Tintut Y, Demer LL. PMID: 20664518; PMCID: PMC3014092.
      View in: PubMed   Mentions: 211     Fields:    Translation:HumansCells
    62. The bone-vascular axis in chronic kidney disease. Curr Opin Nephrol Hypertens. 2010 Jul; 19(4):349-53. Demer L, Tintut Y. PMID: 20508522; PMCID: PMC3001327.
      View in: PubMed   Mentions: 23     Fields:    Translation:HumansAnimals
    63. Regulation of interleukin-6 expression in osteoblasts by oxidized phospholipids. J Lipid Res. 2010 May; 51(5):1010-6. Tseng W, Lu J, Bishop GA, Watson AD, Sage AP, Demer L, Tintut Y. PMID: 19965598; PMCID: PMC2853427.
      View in: PubMed   Mentions: 10     Fields:    Translation:AnimalsCells
    64. Oxidized lipids enhance RANKL production by T lymphocytes: implications for lipid-induced bone loss. Clin Immunol. 2009 Nov; 133(2):265-75. Graham LS, Parhami F, Tintut Y, Kitchen CM, Demer LL, Effros RB. PMID: 19699688; PMCID: PMC2805272.
      View in: PubMed   Mentions: 35     Fields:    Translation:HumansAnimalsCells
    65. Mechanisms linking osteoporosis with cardiovascular calcification. Curr Osteoporos Rep. 2009 Jul; 7(2):42-6. Demer LL, Tintut Y. PMID: 19631027; PMCID: PMC4422187.
      View in: PubMed   Mentions: 12     Fields:    Translation:Humans
    66. Mechanical stress analysis of a rigid inclusion in distensible material: a model of atherosclerotic calcification and plaque vulnerability. Am J Physiol Heart Circ Physiol. 2009 Aug; 297(2):H802-10. Hoshino T, Chow LA, Hsu JJ, Perlowski AA, Abedin M, Tobis J, Tintut Y, Mal AK, Klug WS, Demer LL. PMID: 19542489; PMCID: PMC2724207.
      View in: PubMed   Mentions: 44     Fields:    Translation:Humans
    67. Systems biology of vascular calcification. Trends Cardiovasc Med. 2009 May; 19(4):118-23. Sage A, Tintut Y, Garfinkel A, Demer L. PMID: 19818947; PMCID: PMC2824648.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCells
    68. T0901317, an LXR agonist, augments PKA-induced vascular cell calcification. FEBS Lett. 2009 Apr 17; 583(8):1344-8. Hsu JJ, Lu J, Huang MS, Geng Y, Sage AP, Bradley MN, Tontonoz P, Demer LL, Tintut Y. PMID: 19327357; PMCID: PMC2692939.
      View in: PubMed   Mentions: 13     Fields:    Translation:AnimalsCells
    69. Nanoscale architecture in atherosclerotic calcification. Arterioscler Thromb Vasc Biol. 2008 Nov; 28(11):1882-4. Demer LL, Sage AP, Tintut Y. PMID: 18946051; PMCID: PMC4426492.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimalsCells
    70. Hyperlipidemia impairs osteoanabolic effects of PTH. J Bone Miner Res. 2008 Oct; 23(10):1672-9. Huang MS, Lu J, Ivanov Y, Sage AP, Tseng W, Demer LL, Tintut Y. PMID: 18505371; PMCID: PMC2576281.
      View in: PubMed   Mentions: 23     Fields:    Translation:AnimalsCells
    71. Phosphate and pyrophosphate mediate PKA-induced vascular cell calcification. Biochem Biophys Res Commun. 2008 Sep 26; 374(3):553-8. Huang MS, Sage AP, Lu J, Demer LL, Tintut Y. PMID: 18655772; PMCID: PMC2570192.
      View in: PubMed   Mentions: 28     Fields:    Translation:AnimalsCells
    72. Vitamin D and osteogenic differentiation in the artery wall. Clin J Am Soc Nephrol. 2008 Sep; 3(5):1542-7. Hsu JJ, Tintut Y, Demer LL. PMID: 18562594; PMCID: PMC4571147.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansAnimalsCells
    73. Vascular calcification: pathobiology of a multifaceted disease. Circulation. 2008 Jun 03; 117(22):2938-48. Demer LL, Tintut Y. PMID: 18519861; PMCID: PMC4431628.
      View in: PubMed   Mentions: 426     Fields:    Translation:Humans
    74. Murine models of atherosclerotic calcification. Curr Drug Targets. 2008 Mar; 9(3):224-8. Hsu JJ, Tintut Y, Demer LL. PMID: 18336241.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimals
    75. Osteoprotegerin inhibits vascular calcification without affecting atherosclerosis in ldlr(-/-) mice. Circulation. 2008 Jan 22; 117(3):411-20. Morony S, Tintut Y, Zhang Z, Cattley RC, Van G, Dwyer D, Stolina M, Kostenuik PJ, Demer LL. PMID: 18172035; PMCID: PMC2680735.
      View in: PubMed   Mentions: 99     Fields:    Translation:Animals
    76. A matter of degree: a commentary on "Influence of oxidized low-density lipoproteins (LDL) on the viability of osteoblastic cells". Free Radic Biol Med. 2008 Feb 15; 44(4):504-5. Demer LL, Tintut Y. PMID: 18005672.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    77. Vascular calcification. J Musculoskelet Neuronal Interact. 2007 Oct-Dec; 7(4):346. Tintut Y, Huang M, Lu J, Tseng W, Garfinkel A, Demer LL. PMID: 18094506.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    78. Atherogenic phospholipids attenuate osteogenic signaling by BMP-2 and parathyroid hormone in osteoblasts. J Biol Chem. 2007 Jul 20; 282(29):21237-43. Huang MS, Morony S, Lu J, Zhang Z, Bezouglaia O, Tseng W, Tetradis S, Demer LL, Tintut Y. PMID: 17522049; PMCID: PMC3001330.
      View in: PubMed   Mentions: 29     Fields:    Translation:AnimalsCells
    79. Mineralocorticoid receptor activation promotes vascular cell calcification. Arterioscler Thromb Vasc Biol. 2007 Apr; 27(4):799-805. Jaffe IZ, Tintut Y, Newfell BG, Demer LL, Mendelsohn ME. PMID: 17234727.
      View in: PubMed   Mentions: 56     Fields:    Translation:HumansAnimalsCells
    80. Role of osteoprotegerin and its ligands and competing receptors in atherosclerotic calcification. J Investig Med. 2006 Nov; 54(7):395-401. Tintut Y, Demer L. PMID: 17169261.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansAnimals
    81. Mechanical response of a calcified plaque model to fluid shear force. Ann Biomed Eng. 2006 Oct; 34(10):1535-41. Lin TC, Tintut Y, Lyman A, Mack W, Demer LL, Hsiai TK. PMID: 17006755.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansCells
    82. Pitting phosphate transport inhibitors against vascular calcification. Circ Res. 2006 Apr 14; 98(7):857-9. Demer LL, Tintut Y. PMID: 16614308.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimals
    83. N-3 fatty acids inhibit vascular calcification via the p38-mitogen-activated protein kinase and peroxisome proliferator-activated receptor-gamma pathways. Circ Res. 2006 Mar 31; 98(6):727-9. Abedin M, Lim J, Tang TB, Park D, Demer LL, Tintut Y. PMID: 16514067.
      View in: PubMed   Mentions: 44     Fields:    Translation:AnimalsCells
    84. Regulation of RANKL-induced osteoclastic differentiation by vascular cells. J Mol Cell Cardiol. 2005 Aug; 39(2):389-93. Tintut Y, Abedin M, Cho J, Choe A, Lim J, Demer LL. PMID: 15893766.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansAnimalsCells
    85. Return to ectopia: stem cells in the artery wall. Arterioscler Thromb Vasc Biol. 2005 Jul; 25(7):1307-8. Demer LL, Tintut Y. PMID: 15980267.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimalsCells
    86. Insulin-like growth factor-I regulates proliferation and osteoblastic differentiation of calcifying vascular cells via extracellular signal-regulated protein kinase and phosphatidylinositol 3-kinase pathways. Circ Res. 2005 Mar 04; 96(4):398-400. Radcliff K, Tang TB, Lim J, Zhang Z, Abedin M, Demer LL, Tintut Y. PMID: 15692088.
      View in: PubMed   Mentions: 40     Fields:    Translation:HumansAnimalsCells
    87. Mesenchymal stem cells and the artery wall. Circ Res. 2004 Oct 01; 95(7):671-6. Abedin M, Tintut Y, Demer LL. PMID: 15459088.
      View in: PubMed   Mentions: 63     Fields:    Translation:HumansAnimalsCells
    88. Pattern formation by vascular mesenchymal cells. Proc Natl Acad Sci U S A. 2004 Jun 22; 101(25):9247-50. Garfinkel A, Tintut Y, Petrasek D, Boström K, Demer LL. PMID: 15197273; PMCID: PMC438961.
      View in: PubMed   Mentions: 47     Fields:    Translation:Animals
    89. Vascular calcification: mechanisms and clinical ramifications. Arterioscler Thromb Vasc Biol. 2004 Jul; 24(7):1161-70. Abedin M, Tintut Y, Demer LL. PMID: 15155384.
      View in: PubMed   Mentions: 282     Fields:    Translation:HumansAnimals
    90. Hyperlipidemia promotes osteoclastic potential of bone marrow cells ex vivo. Arterioscler Thromb Vasc Biol. 2004 Feb; 24(2):e6-10. Tintut Y, Morony S, Demer LL. PMID: 14670933.
      View in: PubMed   Mentions: 81     Fields:    Translation:AnimalsCells
    91. Multilineage potential of cells from the artery wall. Circulation. 2003 Nov 18; 108(20):2505-10. Tintut Y, Alfonso Z, Saini T, Radcliff K, Watson K, Boström K, Demer LL. PMID: 14581408.
      View in: PubMed   Mentions: 113     Fields:    Translation:AnimalsCells
    92. Mineral exploration: search for the mechanism of vascular calcification and beyond: the 2003 Jeffrey M. Hoeg Award lecture. Arterioscler Thromb Vasc Biol. 2003 Oct 01; 23(10):1739-43. Demer LL, Tintut Y. PMID: 12958041.
      View in: PubMed   Mentions: 37     Fields:    Translation:AnimalsCells
    93. Vascular calcification and its relation to bone calcification: possible underlying mechanisms. J Nucl Cardiol. 2003 Mar-Apr; 10(2):177-83. Mody N, Tintut Y, Radcliff K, Demer LL. PMID: 12673183.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansAnimals
    94. Role of the cholesterol biosynthetic pathway in osteoblastic differentiation of marrow stromal cells. J Bone Miner Res. 2002 Nov; 17(11):1997-2003. Parhami F, Mody N, Gharavi N, Ballard AJ, Tintut Y, Demer LL. PMID: 12412807.
      View in: PubMed   Mentions: 24     Fields:    Translation:HumansAnimalsCells
    95. High-density lipoprotein regulates calcification of vascular cells. Circ Res. 2002 Oct 04; 91(7):570-6. Parhami F, Basseri B, Hwang J, Tintut Y, Demer LL. PMID: 12364384.
      View in: PubMed   Mentions: 61     Fields:    Translation:AnimalsCells
    96. Novel mechanisms in accelerated vascular calcification in renal disease patients. Curr Opin Nephrol Hypertens. 2002 Jul; 11(4):437-43. Demer LL, Tintut Y, Parhami F. PMID: 12105395.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansAnimals
    97. Monocyte/macrophage regulation of vascular calcification in vitro. Circulation. 2002 Feb 05; 105(5):650-5. Tintut Y, Patel J, Territo M, Saini T, Parhami F, Demer LL. PMID: 11827934.
      View in: PubMed   Mentions: 109     Fields:    Translation:HumansAnimalsCells
    98. 8-Isoprostaglandin E2 enhances receptor-activated NFkappa B ligand (RANKL)-dependent osteoclastic potential of marrow hematopoietic precursors via the cAMP pathway. J Biol Chem. 2002 Apr 19; 277(16):14221-6. Tintut Y, Parhami F, Tsingotjidou A, Tetradis S, Territo M, Demer LL. PMID: 11827970.
      View in: PubMed   Mentions: 54     Fields:    Translation:AnimalsCells
    99. Recent advances in multifactorial regulation of vascular calcification. Curr Opin Lipidol. 2001 Oct; 12(5):555-60. Tintut Y, Demer LL. PMID: 11561176.
      View in: PubMed   Mentions: 31     Fields:    Translation:HumansAnimals
    100. Leptin enhances the calcification of vascular cells: artery wall as a target of leptin. Circ Res. 2001 May 11; 88(9):954-60. Parhami F, Tintut Y, Ballard A, Fogelman AM, Demer LL. PMID: 11349006.
      View in: PubMed   Mentions: 66     Fields:    Translation:AnimalsCells
    101. Regulation of vascular calcification in atherosclerosis. Z Kardiol. 2001; 90 Suppl 3:27-30. Parhami F, Tintut Y, Patel JK, Mody N, Hemmat A, Demer LL. PMID: 11374029.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    102. Atherogenic high-fat diet reduces bone mineralization in mice. J Bone Miner Res. 2001 Jan; 16(1):182-8. Parhami F, Tintut Y, Beamer WG, Gharavi N, Goodman W, Demer LL. PMID: 11149483.
      View in: PubMed   Mentions: 104     Fields:    Translation:AnimalsCells
    103. Tumor necrosis factor-alpha promotes in vitro calcification of vascular cells via the cAMP pathway. Circulation. 2000 Nov 21; 102(21):2636-42. Tintut Y, Patel J, Parhami F, Demer LL. PMID: 11085968.
      View in: PubMed   Mentions: 180     Fields:    Translation:AnimalsCells
    104. HOXB7 overexpression promotes differentiation of C3H10T1/2 cells to smooth muscle cells. J Cell Biochem. 2000 May; 78(2):210-21. Boström K, Tintut Y, Kao SC, Stanford WP, Demer LL. PMID: 10842316.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansAnimalsCells
    105. Atherogenic diet and minimally oxidized low density lipoprotein inhibit osteogenic and promote adipogenic differentiation of marrow stromal cells. J Bone Miner Res. 1999 Dec; 14(12):2067-78. Parhami F, Jackson SM, Tintut Y, Le V, Balucan JP, Territo M, Demer LL. PMID: 10620066.
      View in: PubMed   Mentions: 81     Fields:    Translation:HumansAnimalsCells
    106. Inhibition of osteoblast-specific transcription factor Cbfa1 by the cAMP pathway in osteoblastic cells. Ubiquitin/proteasome-dependent regulation. J Biol Chem. 1999 Oct 08; 274(41):28875-9. Tintut Y, Parhami F, Le V, Karsenty G, Demer LL. PMID: 10506130.
      View in: PubMed   Mentions: 35     Fields:    Translation:AnimalsCells
    107. Osteopontin. Between a rock and a hard plaque. Circ Res. 1999 Feb 05; 84(2):250-2. Demer LL, Tintut Y. PMID: 9933258.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    108. cAMP stimulates osteoblast-like differentiation of calcifying vascular cells. Potential signaling pathway for vascular calcification. J Biol Chem. 1998 Mar 27; 273(13):7547-53. Tintut Y, Parhami F, Boström K, Jackson SM, Demer LL. PMID: 9516456.
      View in: PubMed   Mentions: 55     Fields:    Translation:AnimalsCells
    109. Lipid oxidation products have opposite effects on calcifying vascular cell and bone cell differentiation. A possible explanation for the paradox of arterial calcification in osteoporotic patients. Arterioscler Thromb Vasc Biol. 1997 Apr; 17(4):680-7. Parhami F, Morrow AD, Balucan J, Leitinger N, Watson AD, Tintut Y, Berliner JA, Demer LL. PMID: 9108780.
      View in: PubMed   Mentions: 186     Fields:    Translation:AnimalsCells
    110. Abortive cycling and the release of polymerase for elongation at the sigma 54-dependent glnAp2 promoter. J Biol Chem. 1995 Oct 13; 270(41):24392-8. Tintut Y, Wang JT, Gralla JD. PMID: 7592652.
      View in: PubMed   Mentions: 5     Fields:    Translation:Cells
    111. PCR mutagenesis identifies a polymerase-binding sequence of sigma 54 that includes a sigma 70 homology region. J Bacteriol. 1995 Oct; 177(20):5818-25. Tintut Y, Gralla JD. PMID: 7592329; PMCID: PMC177404.
      View in: PubMed   Mentions: 18     Fields:    Translation:Cells
    112. A novel bacterial transcription cycle involving sigma 54. Genes Dev. 1995 Sep 15; 9(18):2305-13. Tintut Y, Wang JT, Gralla JD. PMID: 7557383.
      View in: PubMed   Mentions: 17     Fields:    Translation:Cells
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