Theodore C Friedman

Title(s)Professor-in-Residence, Medicine
SchoolMedicine
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    Collapse Research 
    Collapse Research Activities and Funding
    The Next Generation Substance Abuse Research Training at Charles R. Drew University (CDU) and UCLA (NGSART-CU)
    NIH R25DA050723Apr 1, 2020 - Mar 31, 2025
    Role: Principal Investigator
    Novel pathways in the pathogenesis and pathophysiology of NAFLD in Hispanics
    NIH R01MD012579Mar 12, 2019 - Nov 30, 2023
    Role: Co-Principal Investigator
    The mechanisms of the nicotine-induction of insulin resistance
    NIH R21DA022342Sep 30, 2007 - Aug 31, 2010
    Role: Principal Investigator
    CDU Diversity-promoting Institutions Drug Abuse Research Development Program
    NIH R24DA017298Sep 1, 2003 - Mar 31, 2021
    Role: Principal Investigator
    THE BIOLOGIC EFFECTS OF ANDROGENS IN MEN AND WOMEN
    NIH U54HD041748Aug 15, 2003 - Oct 31, 2010
    Role: Principal Investigator
    Support of Competitive Research (SCORE) Institutional Development Award at Drew
    NIH S06GM068510Aug 1, 2003 - Aug 31, 2012
    Role: Co-Principal Investigator
    Chronic Nicotine's Activation of the HPA Axis
    NIH R21DA016867Jul 20, 2003 - May 31, 2007
    Role: Principal Investigator
    HPA Axis Activation and Nicotine Use
    NIH R21DA015466Jun 5, 2003 - Feb 29, 2008
    Role: Principal Investigator
    Genes and Proteins Leading to Addiction
    NIH R01DA014659Aug 1, 2002 - Jul 31, 2010
    Role: Principal Investigator
    STRUCTURAL DETERMINANTS IN REGULATION OF POMC PROCESSING
    NIH K21DA000276Jul 1, 1995 - Apr 30, 2001
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Hepatic steatosis induced by nicotine plus Coca-Cola™ is prevented by nicotinamide riboside (NR). Front Endocrinol (Lausanne). 2024; 15:1282231. Rivera JC, Espinoza-Derout J, Hasan KM, Molina-Mancio J, Martínez J, Lao CJ, Lee ML, Lee DL, Wilson J, Sinha-Hikim AP, Friedman TC. PMID: 38756999; PMCID: PMC11097688.
      View in: PubMed   Mentions:    Fields:    Translation:Animals
    2. Neuroendocrine mechanisms in the links between early life stress, affect, and youth substance use: A conceptual model for the study of sex and gender differences. Front Neuroendocrinol. 2024 Apr; 73:101121. Donovan A, Assari S, Grella C, Shaheen M, Richter L, Friedman TC. PMID: 38253240; PMCID: PMC11088508.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    3. The lipolysis inhibitor acipimox reverses the cardiac phenotype induced by electronic cigarettes. Sci Rep. 2023 10 25; 13(1):18239. Espinoza-Derout J, Arambulo JML, Ramirez-Trillo W, Rivera JC, Hasan KM, Lao CJ, Jordan MC, Shao XM, Roos KP, Sinha-Hikim AP, Friedman TC. PMID: 37880325; PMCID: PMC10600141.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    4. Implementation of Specialty Tobacco Use Disorder Services in a Community Health Setting: Support for Enhanced Prescription Practices. J Addict Med. 2023 Nov-Dec 01; 17(6):677-684. Meredith LR, Hurley B, Friedman TC, Lee ML, Rodriguez L, Lopez B, Mtume N, Dixon T, Belani HK, Hsieh S, Ray LA. PMID: 37934530.
      View in: PubMed   Mentions:    Fields:    Translation:HumansPHPublic Health
    5. The role of Neurochemicals, Stress Hormones and Immune System in the Positive Feedback Loops between Diabetes, Obesity and Depression. Front Endocrinol (Lausanne). 2023; 14:1224612. Wilson JB, Epstein M, Lopez B, Brown AK, Lutfy K, Friedman TC. PMID: 37664841; PMCID: PMC10470111.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    6. Fatty Acid Excess Dysregulates CARF to Initiate the Development of Hepatic Steatosis. Cells. 2023 04 01; 12(7). Hasan KM, Parveen M, Pena A, Bautista F, Rivera JC, Huerta RR, Martinez E, Espinoza-Derout J, Sinha-Hikim AP, Friedman TC. PMID: 37048142; PMCID: PMC10093423.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    7. Racial/ethnic and gender disparity in the severity of NAFLD among people with diabetes or prediabetes. Front Physiol. 2023; 14:1076730. Shaheen M, Schrode KM, Tedlos M, Pan D, Najjar SM, Friedman TC. PMID: 36891143; PMCID: PMC9986441.
      View in: PubMed   Mentions: 1  
    8. Electronic Cigarette Use and the Risk of Cardiovascular Diseases. Front Cardiovasc Med. 2022; 9:879726. Espinoza-Derout J, Shao XM, Lao CJ, Hasan KM, Rivera JC, Jordan MC, Echeverria V, Roos KP, Sinha-Hikim AP, Friedman TC. PMID: 35463745; PMCID: PMC9021536.
      View in: PubMed   Mentions: 23  
    9. A New Ingenious Enemy: Heat-Not-Burn Products. Tob Use Insights. 2022; 15:1179173X221076419. Kim SC, Friedman TC. PMID: 35237081; PMCID: PMC8883376.
      View in: PubMed   Mentions: 9  
    10. Embedding comprehensive smoking cessation programs into community clinics: study protocol for a cluster-randomized controlled trial. Trials. 2022 Feb 03; 23(1):109. Baskerville WA, Friedman TC, Hurley B, Hsieh S, Dixon T, Mtume N, Lee ML, Rodriguez L, Lopez B, Ray LA. PMID: 35115017; PMCID: PMC8811740.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCTClinical Trials
    11. Sex-Specific Differences in the Association Between Race/Ethnicity and NAFLD Among US Population. Front Med (Lausanne). 2021; 8:795421. Shaheen M, Schrode KM, Pan D, Kermah D, Puri V, Zarrinpar A, Elisha D, Najjar SM, Friedman TC. PMID: 34926533; PMCID: PMC8674562.
      View in: PubMed   Mentions: 11  
    12. US Tobacco 21 is Paving the Way for a Tobacco Endgame. Tob Use Insights. 2021; 14:1179173X211050396. Kim SCJ, Martinez JE, Liu Y, Friedman TC. PMID: 34866950; PMCID: PMC8637783.
      View in: PubMed   Mentions: 3  
    13. Safety Net Provider Attitudes Toward Smoking Cessation Treatment. Front Psychiatry. 2021; 12:744816. Meredith LR, Baskerville WA, Friedman TC, Hurley B, Dixon T, Mtume N, Rodriguez L, Lopez B, Hsieh S, Ray LA. PMID: 34650457; PMCID: PMC8505698.
      View in: PubMed   Mentions:
    14. Reassessment of the Hispanic Disparity: Hepatic Steatosis Is More Prevalent in Mexican Americans Than Other Hispanics. Hepatol Commun. 2021 12; 5(12):2068-2079. Shaheen M, Pan D, Schrode KM, Kermah D, Puri V, Zarrinpar A, Elisha D, Najjar SM, Friedman TC. PMID: 34558824; PMCID: PMC8631095.
      View in: PubMed   Mentions: 11     Fields:    Translation:Humans
    15. Supporting "Bleeders" and "Billers": How Safety-Net Administrators Mitigate Provider Burnout During the COVID-19 Pandemic and Beyond. J Ambul Care Manage. 2021 Jul-Sep 01; 44(3):172-183. Martinez-Hollingsworth A, Kim L, Richardson TG, Angulo M, Liu R, Friedman T, Choi K. PMID: 34016846; PMCID: PMC8174579.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCellsPHPublic Health
    16. Unhealthy Lifestyle and Gut Dysbiosis: A Better Understanding of the Effects of Poor Diet and Nicotine on the Intestinal Microbiome. Front Endocrinol (Lausanne). 2021; 12:667066. Martinez JE, Kahana DD, Ghuman S, Wilson HP, Wilson J, Kim SCJ, Lagishetty V, Jacobs JP, Sinha-Hikim AP, Friedman TC. PMID: 34168615; PMCID: PMC8218903.
      View in: PubMed   Mentions: 67     Fields:    Translation:Humans
    17. Implementing texting programs in the P.O.W.E.R. (preventing obesity with eating right) medical group visit for weight loss. Obes Sci Pract. 2021 Oct; 7(5):583-590. Saldivar P, Mira V, Duran P, Moldovan C, Ang G, Parikh N, Lee ML, Friedman TC. PMID: 34631136; PMCID: PMC8488446.
      View in: PubMed   Mentions: 2  
    18. Decreased 11β-Hydroxysteroid Dehydrogenase Type 2 Expression in the Kidney May Contribute to Nicotine/Smoking-Induced Blood Pressure Elevation in Mice. Hypertension. 2021 06; 77(6):1940-1952. Wang Y, Wang J, Yang R, Wang P, Porche R, Kim S, Lutfy K, Liu L, Friedman TC, Jiang M, Liu Y. PMID: 33813843; PMCID: PMC8119334.
      View in: PubMed   Mentions: 5     Fields:    Translation:AnimalsCells
    19. The Combination of High-Fat Diet and Oral Marijuana Promotes the Development of Fibrosis in the Mouse Corpora Cavernosa. Sex Med. 2021 Apr; 9(2):100312. Nguyen S, Mangubat M, Eleswarapu S, Wilson JB, Molina J, Abraham A, Artaza JN, Friedman TC, Ferrini MG. PMID: 33540365; PMCID: PMC8072182.
      View in: PubMed   Mentions: 2  
    20. Metabolic parameters in smokers undergoing smoking reduction. J Clin Transl Endocrinol. 2021 Mar; 23:100249. Hsia SH, Nisis ML, Lee ML, Goldstein C, Friedman TC. PMID: 33717989; PMCID: PMC7933731.
      View in: PubMed   Mentions:
    21. Prevalence and Predictors of Nonalcoholic Steatohepatitis Using Multiple Non-Invasive Methods: Data from NHANES III. J Liver. 2020; 9(3). Shaheen M, Schrode KM, Kermah D, Pan D, Puri V, Zarrinpar A, Elisha D, Najjar SM, Friedman TC. PMID: 37786752; PMCID: PMC10544753.
      View in: PubMed   Mentions: 1  
    22. Nicotine Synergizes with High-Fat Diet to Induce an Anti-Inflammatory Microenvironment to Promote Breast Tumor Growth. Mediators Inflamm. 2020; 2020:5239419. Jimenez T, Friedman T, Vadgama J, Singh V, Tucker A, Collazo J, Sinha S, Hikim AS, Singh R, Pervin S. PMID: 33414685; PMCID: PMC7752272.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimalsCells
    23. Adverse effects of fetal exposure of electronic-cigarettes and high-fat diet on male neonatal hearts. Exp Mol Pathol. 2021 02; 118:104573. Hasan KM, Munoz A, Tumoyan H, Parveen M, Espinoza-Derout J, Shao XM, Mahata SK, Friedman TC, Sinha-Hikim AP. PMID: 33212125; PMCID: PMC8501912.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    24. High Prevalence of Adrenal Remnant Tissue in Patients Undergoing Bilateral Adrenalectomy for Cushing's Disease. Horm Metab Res. 2021 Mar; 53(3):161-168. Wilson JB, Zopey M, Augustine J, Schaffer R, Chiang M, Friedman TC. PMID: 33091942; PMCID: PMC8570053.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    25. Electronic cigarettes cause alteration in cardiac structure and function in diet-induced obese mice. PLoS One. 2020; 15(10):e0239671. Hasan KM, Friedman TC, Parveen M, Espinoza-Derout J, Bautista F, Razipour MM, Shao XM, Jordan MC, Roos KP, Mahata SK, Sinha-Hikim AP. PMID: 33002059; PMCID: PMC7529198.
      View in: PubMed   Mentions: 10     Fields:    Translation:Animals
    26. Last Word on Viewpoint: pH Buffer capacity and pharmacokinetics: two remaining questions. J Appl Physiol (1985). 2020 04 01; 128(4):1063-1064. Shao XM, Friedman TC. PMID: 32284007; PMCID: PMC7276929.
      View in: PubMed   Mentions: 1     Fields:    
    27. Pod-mod vs. conventional e-cigarettes: nicotine chemistry, pH, and health effects. J Appl Physiol (1985). 2020 04 01; 128(4):1056-1058. Shao XM, Friedman TC. PMID: 31854246; PMCID: PMC7191502.
      View in: PubMed   Mentions: 34     Fields:    
    28. Lack of adipose-specific hexose-6-phosphate dehydrogenase causes inactivation of adipose glucocorticoids and improves metabolic phenotype in mice. Clin Sci (Lond). 2019 11 15; 133(21):2189-2202. Wang J, Wang Y, Liu L, Lutfy K, Friedman TC, Liu Y, Jiang M, Liu Y. PMID: 31696216; PMCID: PMC7493827.
      View in: PubMed   Mentions: 2     Fields:    Translation:Animals
    29. A mouse model for chronic intermittent electronic cigarette exposure exhibits nicotine pharmacokinetics resembling human vapers. J Neurosci Methods. 2019 10 01; 326:108376. Shao XM, Lopez B, Nathan D, Wilson J, Bankole E, Tumoyan H, Munoz A, Espinoza-Derout J, Hasan KM, Chang S, Du C, Sinha-Hikim AP, Lutfy K, Friedman TC. PMID: 31361999; PMCID: PMC6717674.
      View in: PubMed   Mentions: 24     Fields:    Translation:Animals
    30. Chronic intermittent electronic cigarette exposure induces cardiac dysfunction and atherosclerosis in apolipoprotein-E knockout mice. Am J Physiol Heart Circ Physiol. 2019 08 01; 317(2):H445-H459. Espinoza-Derout J, Hasan KM, Shao XM, Jordan MC, Sims C, Lee DL, Sinha S, Simmons Z, Mtume N, Liu Y, Roos KP, Sinha-Hikim AP, Friedman TC. PMID: 31172811; PMCID: PMC6732484.
      View in: PubMed   Mentions: 44     Fields:    Translation:AnimalsCellsPHPublic Health
    31. Hepatic DNA Damage Induced by Electronic Cigarette Exposure Is Associated With the Modulation of NAD+/PARP1/SIRT1 Axis. Front Endocrinol (Lausanne). 2019; 10:320. Espinoza-Derout J, Shao XM, Bankole E, Hasan KM, Mtume N, Liu Y, Sinha-Hikim AP, Friedman TC. PMID: 31214115; PMCID: PMC6558099.
      View in: PubMed   Mentions: 15     Fields:    
    32. E-cigarettes and Western Diet: Important Metabolic Risk Factors for Hepatic Diseases. Hepatology. 2019 06; 69(6):2442-2454. Hasan KM, Friedman TC, Shao X, Parveen M, Sims C, Lee DL, Espinoza-Derout J, Sinha-Hikim I, Sinha-Hikim AP. PMID: 30664268; PMCID: PMC6636679.
      View in: PubMed   Mentions: 23     Fields:    Translation:HumansAnimals
    33. Low-Dose and Standard Overnight and Low Dose-Two Day Dexamethasone Suppression Tests in Patients with Mild and/or Episodic Hypercortisolism. Horm Metab Res. 2018 Jun; 50(6):453-461. Mojtahedzadeh M, Shaesteh N, Haykani M, Tran JLA, Mangubat M, Shahinian HK, Nachnani R, Zopey M, Saidian J, Thomas A, Lee ML, McCutcheon IE, Friedman TC. PMID: 29719879; PMCID: PMC6502760.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    34. Enhanced hexose-6-phosphate dehydrogenase expression in adipose tissue may contribute to diet-induced visceral adiposity. Int J Obes (Lond). 2018 12; 42(12):1999-2011. Liu L, Wang Y, Wang J, Dong Y, Chang S, Liu X, Lutfy K, Chen H, Friedman TC, Jiang M, Liu Y. PMID: 29568102; PMCID: PMC6105561.
      View in: PubMed   Mentions: 4     Fields:    Translation:AnimalsCells
    35. α7-Nicotinic Acetylcholine Receptor Agonist Ameliorates Nicotine Plus High-Fat Diet-Induced Hepatic Steatosis in Male Mice by Inhibiting Oxidative Stress and Stimulating AMPK Signaling. Endocrinology. 2018 02 01; 159(2):931-944. Hasan MK, Friedman TC, Sims C, Lee DL, Espinoza-Derout J, Ume A, Chalfant V, Lee ML, Sinha-Hikim I, Lutfy K, Liu Y, Mahata SK, Sinha-Hikim AP. PMID: 29272360; PMCID: PMC5776480.
      View in: PubMed   Mentions: 14     Fields:    Translation:AnimalsCells
    36. Association between secondhand smoke and obesity and glucose abnormalities: data from the National Health and Nutrition Examination Survey (NHANES 1999-2010). BMJ Open Diabetes Res Care. 2017; 5(1):e000324. Kermah D, Shaheen M, Pan D, Friedman TC. PMID: 28405342; PMCID: PMC5372029.
      View in: PubMed   Mentions: 14  
    37. Connection of Nicotine to Diet-Induced Obesity and Non-Alcoholic Fatty Liver Disease: Cellular and Mechanistic Insights. Front Endocrinol (Lausanne). 2017; 8:23. Sinha-Hikim AP, Sinha-Hikim I, Friedman TC. PMID: 28239368; PMCID: PMC5300964.
      View in: PubMed   Mentions: 21     Fields:    
    38. Nicotine plus a high-fat diet triggers cardiomyocyte apoptosis. Cell Tissue Res. 2017 04; 368(1):159-170. Sinha-Hikim I, Friedman TC, Falz M, Chalfant V, Hasan MK, Espinoza-Derout J, Lee DL, Sims C, Tran P, Mahata SK, Sinha-Hikim AP. PMID: 27917437; PMCID: PMC5813800.
      View in: PubMed   Mentions: 14     Fields:    Translation:AnimalsCells
    39. Metabolic effects of smoking cessation. Nat Rev Endocrinol. 2016 11; 12(11):684. Harris KK, Zopey M, Friedman TC. PMID: 27688045.
      View in: PubMed   Mentions: 14     Fields:    
    40. Metabolic effects of smoking cessation. Nat Rev Endocrinol. 2016 May; 12(5):299-308. Harris KK, Zopey M, Friedman TC. PMID: 26939981; PMCID: PMC5021526.
      View in: PubMed   Mentions: 65     Fields:    Translation:Humans
    41. Continuation or discontinuation of pioglitazone when starting bedtime insulin in patients with poorly controlled type 2 diabetes in an inner-city population. J Diabetes Complications. 2015 Nov-Dec; 29(8):1248-52. Mojtahedzadeh M, Lee ML, Friedman TC. PMID: 26215435; PMCID: PMC5014540.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    42. 11β-Hydroxysteroid dehydrogenase type 1 shRNA ameliorates glucocorticoid-induced insulin resistance and lipolysis in mouse abdominal adipose tissue. Am J Physiol Endocrinol Metab. 2015 Jan 01; 308(1):E84-95. Wang Y, Yan C, Liu L, Wang W, Du H, Fan W, Lutfy K, Jiang M, Friedman TC, Liu Y. PMID: 25389364; PMCID: PMC4281684.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansAnimalsCells
    43. Testosterone dose-response relationships in hysterectomized women with or without oophorectomy: effects on sexual function, body composition, muscle performance and physical function in a randomized trial. Menopause. 2014 Jun; 21(6):612-23. Huang G, Basaria S, Travison TG, Ho MH, Davda M, Mazer NA, Miciek R, Knapp PE, Zhang A, Collins L, Ursino M, Appleman E, Dzekov C, Stroh H, Ouellette M, Rundell T, Baby M, Bhatia NN, Khorram O, Friedman T, Storer TW, Bhasin S. PMID: 24281237; PMCID: PMC4701202.
      View in: PubMed   Mentions: 35     Fields:    Translation:Humans
    44. Nicotine in combination with a high-fat diet causes intramyocellular mitochondrial abnormalities in male mice. Endocrinology. 2014 Mar; 155(3):865-72. Sinha-Hikim I, Friedman TC, Shin CS, Lee D, Ivey R, Sinha-Hikim AP. PMID: 24424058; PMCID: PMC3929732.
      View in: PubMed   Mentions: 17     Fields:    Translation:AnimalsCells
    45. Transgenic overexpression of hexose-6-phosphate dehydrogenase in adipose tissue causes local glucocorticoid amplification and lipolysis in male mice. Am J Physiol Endocrinol Metab. 2014 Mar 01; 306(5):E543-51. Wang Y, Liu L, Du H, Nagaoka Y, Fan W, Lutfy K, Friedman TC, Jiang M, Liu Y. PMID: 24381005; PMCID: PMC3948972.
      View in: PubMed   Mentions: 7     Fields:    Translation:AnimalsCells
    46. Adolescence is a period of development characterized by short- and long-term vulnerability to the rewarding effects of nicotine and reduced sensitivity to the anorectic effects of this drug. Behav Brain Res. 2013 Nov 15; 257:275-85. Natividad LA, Torres OV, Friedman TC, O'Dell LE. PMID: 24120402; PMCID: PMC3965174.
      View in: PubMed   Mentions: 24     Fields:    Translation:Animals
    47. Mutations in KCNJ11 are associated with the development of autosomal dominant, early-onset type 2 diabetes. Diabetologia. 2013 Dec; 56(12):2609-18. Liu L, Nagashima K, Yasuda T, Liu Y, Hu HR, He G, Feng B, Zhao M, Zhuang L, Zheng T, Friedman TC, Xiang K. PMID: 24018988; PMCID: PMC5333983.
      View in: PubMed   Mentions: 17     Fields:    Translation:Humans
    48. Alterations in phosphorylated CREB expression in different brain regions following short- and long-term morphine exposure: relationship to food intake. J Obes. 2013; 2013:764742. Ren X, Lutfy K, Mangubat M, Ferrini MG, Lee ML, Liu Y, Friedman TC. PMID: 24073333; PMCID: PMC3773431.
      View in: PubMed   Mentions: 11     Fields:    Translation:AnimalsCells
    49. Morphine treatment selectively regulates expression of rat pituitary POMC and the prohormone convertases PC1/3 and PC2. Peptides. 2013 Sep; 47:99-109. Nie Y, Ferrini MG, Liu Y, Anghel A, Paez Espinosa EV, Stuart RC, Lutfy K, Nillni EA, Friedman TC. PMID: 23891651; PMCID: PMC3787842.
      View in: PubMed   Mentions: 2     Fields:    Translation:Animals
    50. Enhanced nicotine self-administration and suppressed dopaminergic systems in a rat model of diabetes. Addict Biol. 2014 Nov; 19(6):1006-19. O'Dell LE, Natividad LA, Pipkin JA, Roman F, Torres I, Jurado J, Torres OV, Friedman TC, Tenayuca JM, Nazarian A. PMID: 23834715; PMCID: PMC3842417.
      View in: PubMed   Mentions: 21     Fields:    Translation:Animals
    51. Specific reduction of G6PT may contribute to downregulation of hepatic 11β-HSD1 in diabetic mice. J Mol Endocrinol. 2013 Apr; 50(2):167-78. Du H, Liu L, Wang Y, Nakagawa Y, Lyzlov A, Lutfy K, Friedman TC, Peng X, Liu Y. PMID: 23267038; PMCID: PMC3763023.
      View in: PubMed   Mentions: 7     Fields:    Translation:AnimalsCells
    52. A Review of Programs, Components and Outcomes in Biomedical Research Faculty Development. Int J Univ Teach Fac Dev. 2013; 4(4):223-236. Teruya SA, Bazargan-Hejazi S, Mojtahedzadeh M, Doshi M, Russell K, Parker-Kelly D, Friedman TC. PMID: 26120379; PMCID: PMC4479301.
      View in: PubMed   Mentions: 3  
    53. Additive effects of nicotine and high-fat diet on hepatic steatosis in male mice. Endocrinology. 2012 Dec; 153(12):5809-20. Friedman TC, Sinha-Hikim I, Parveen M, Najjar SM, Liu Y, Mangubat M, Shin CS, Lyzlov A, Ivey R, Shaheen M, French SW, Sinha-Hikim AP. PMID: 23093702; PMCID: PMC3512067.
      View in: PubMed   Mentions: 32     Fields:    Translation:AnimalsCells
    54. High-dose vitamin D supplementation in people with prediabetes and hypovitaminosis D. Diabetes Care. 2013 Feb; 36(2):260-6. Davidson MB, Duran P, Lee ML, Friedman TC. PMID: 23033239; PMCID: PMC3554269.
      View in: PubMed   Mentions: 89     Fields:    Translation:Humans
    55. The rewarding action of acute cocaine is reduced in β-endorphin deficient but not in μ opioid receptor knockout mice. Eur J Pharmacol. 2012 Jul 05; 686(1-3):50-4. Nguyen AT, Marquez P, Hamid A, Kieffer B, Friedman TC, Lutfy K. PMID: 22575525; PMCID: PMC3367137.
      View in: PubMed   Mentions: 16     Fields:    Translation:Animals
    56. The endocrine effects of nicotine and cigarette smoke. Trends Endocrinol Metab. 2012 Jul; 23(7):334-42. Tweed JO, Hsia SH, Lutfy K, Friedman TC. PMID: 22561025; PMCID: PMC3389568.
      View in: PubMed   Mentions: 72     Fields:    Translation:HumansAnimals
    57. Decreased prevalence of diabetes in marijuana users: cross-sectional data from the National Health and Nutrition Examination Survey (NHANES) III. BMJ Open. 2012; 2:e000494. Rajavashisth TB, Shaheen M, Norris KC, Pan D, Sinha SK, Ortega J, Friedman TC. PMID: 22368296; PMCID: PMC3289985.
      View in: PubMed   Mentions: 66     Fields:    
    58. Nicotine stimulates secretion of corticosterone via both CRH and AVP receptors. J Neurochem. 2012 Mar; 120(6):1108-16. Lutfy K, Aimiuwu O, Mangubat M, Shin CS, Nerio N, Gomez R, Liu Y, Friedman TC. PMID: 22191943; PMCID: PMC3296864.
      View in: PubMed   Mentions: 18     Fields:    Translation:Animals
    59. Effect of nicotine on body composition in mice. J Endocrinol. 2012 Mar; 212(3):317-26. Mangubat M, Lutfy K, Lee ML, Pulido L, Stout D, Davis R, Shin CS, Shahbazian M, Seasholtz S, Sinha-Hikim A, Sinha-Hikim I, O'Dell LE, Lyzlov A, Liu Y, Friedman TC. PMID: 22138237; PMCID: PMC3444240.
      View in: PubMed   Mentions: 33     Fields:    Translation:Animals
    60. Vitamin D supplementation to prevent the progression of prediabetes to diabetes: getting closer to a recommendation. Transl Res. 2011 Nov; 158(5):273-5. Friedman TC. PMID: 22005266; PMCID: PMC3918469.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    61. Stress-induced analgesia and endogenous opioid peptides: the importance of stress duration. Eur J Pharmacol. 2011 Jan 15; 650(2-3):563-7. Parikh D, Hamid A, Friedman TC, Nguyen K, Tseng A, Marquez P, Lutfy K. PMID: 21044625; PMCID: PMC3033575.
      View in: PubMed   Mentions: 32     Fields:    Translation:AnimalsCells
    62. Intraislet production of GLP-1 by activation of prohormone convertase 1/3 in pancreatic α-cells in mouse models of ß-cell regeneration. Islets. 2010 May-Jun; 2(3):149-55. Kilimnik G, Kim A, Steiner DF, Friedman TC, Hara M. PMID: 20657753; PMCID: PMC2908328.
      View in: PubMed   Mentions: 71     Fields:    Translation:AnimalsCells
    63. The Behavioral and Pharmacological Actions of NMDA Receptor Antagonism are Conserved in Zebrafish Larvae. Int J Comp Psychol. 2010; 23(1):82-90. Chen J, Patel R, Friedman TC, Jones KS. PMID: 21278812; PMCID: PMC3027073.
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    64. The effects of opioids and opioid analogs on animal and human endocrine systems. Endocr Rev. 2010 Feb; 31(1):98-132. Vuong C, Van Uum SH, O'Dell LE, Lutfy K, Friedman TC. PMID: 19903933; PMCID: PMC2852206.
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    65. Reduction of hepatic glucocorticoid receptor and hexose-6-phosphate dehydrogenase expression ameliorates diet-induced obesity and insulin resistance in mice. J Mol Endocrinol. 2008 Aug; 41(2):53-64. Liu Y, Nakagawa Y, Wang Y, Liu L, Du H, Wang W, Ren X, Lutfy K, Friedman TC. PMID: 18524870; PMCID: PMC2954685.
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    66. Prevalence of GH and other anterior pituitary hormone deficiencies in adults with nonsecreting pituitary microadenomas and normal serum IGF-1 levels. Clin Endocrinol (Oxf). 2008 Aug; 69(2):292-8. Yuen KC, Cook DM, Sahasranam P, Patel P, Ghods DE, Shahinian HK, Friedman TC. PMID: 18221393; PMCID: PMC2953553.
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    67. Multiglandular parathyroid carcinoma: a case report and brief review. South Med J. 2007 Aug; 100(8):841-4. Sahasranam P, Tran MT, Mohamed H, Friedman TC. PMID: 17713315.
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    68. Repeated stress alters the ability of nicotine to activate the hypothalamic-pituitary-adrenal axis. J Neurochem. 2006 Dec; 99(5):1321-7. Lutfy K, Brown MC, Nerio N, Aimiuwu O, Tran B, Anghel A, Friedman TC. PMID: 17064351.
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    69. Cellular colocalization and coregulation between hypothalamic pro-TRH and prohormone convertases in hypothyroidism. Am J Physiol Endocrinol Metab. 2007 Jan; 292(1):E175-86. Espinosa VP, Ferrini M, Shen X, Lutfy K, Nillni EA, Friedman TC. PMID: 16926379.
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    70. Liver X receptor agonist T0901317 inhibition of glucocorticoid receptor expression in hepatocytes may contribute to the amelioration of diabetic syndrome in db/db mice. Endocrinology. 2006 Nov; 147(11):5061-8. Liu Y, Yan C, Wang Y, Nakagawa Y, Nerio N, Anghel A, Lutfy K, Friedman TC. PMID: 16873540.
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    71. Thyroid hormones selectively regulate the posttranslational processing of prothyrotropin-releasing hormone in the paraventricular nucleus of the hypothalamus. Endocrinology. 2006 Jun; 147(6):2705-16. Perello M, Friedman T, Paez-Espinosa V, Shen X, Stuart RC, Nillni EA. PMID: 16497799.
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    72. Differential involvement of enkephalins in analgesic tolerance, locomotor sensitization, and conditioned place preference induced by morphine. Behav Neurosci. 2006 Feb; 120(1):10-5. Marquez P, Baliram R, Gajawada N, Friedman TC, Lutfy K. PMID: 16492112; PMCID: PMC2268890.
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    73. Glucose dependence of the regulated secretory pathway in alphaTC1-6 cells. Endocrinology. 2005 Oct; 146(10):4514-23. McGirr R, Ejbick CE, Carter DE, Andrews JD, Nie Y, Friedman TC, Dhanvantari S. PMID: 15994347.
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    74. Endocrinomic profile of neurointermediate lobe pituitary prohormone processing in PC1/3- and PC2-Null mice using SELDI-TOF mass spectrometry. J Mol Endocrinol. 2005 Jun; 34(3):739-51. Hardiman A, Friedman TC, Grunwald WC, Furuta M, Zhu Z, Steiner DF, Cool DR. PMID: 15956344; PMCID: PMC4422198.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansAnimalsCells
    75. Regulation of regional expression in rat brain PC2 by thyroid hormone/characterization of novel negative thyroid hormone response elements in the PC2 promoter. Am J Physiol Endocrinol Metab. 2005 Jan; 288(1):E236-45. Shen X, Li QL, Brent GA, Friedman TC. PMID: 15585599.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    76. Increased glucocorticoid receptor and 11{beta}-hydroxysteroid dehydrogenase type 1 expression in hepatocytes may contribute to the phenotype of type 2 diabetes in db/db mice. Diabetes. 2005 Jan; 54(1):32-40. Liu Y, Nakagawa Y, Wang Y, Sakurai R, Tripathi PV, Lutfy K, Friedman TC. PMID: 15616008.
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    77. Regulation of hypothalamic prohormone convertases 1 and 2 and effects on processing of prothyrotropin-releasing hormone. J Clin Invest. 2004 Aug; 114(3):357-69. Sanchez VC, Goldstein J, Stuart RC, Hovanesian V, Huo L, Munzberg H, Friedman TC, Bjorbaek C, Nillni EA. PMID: 15286802; PMCID: PMC484982.
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    78. New testosterone buccal system (Striant) delivers physiological testosterone levels: pharmacokinetics study in hypogonadal men. J Clin Endocrinol Metab. 2004 Aug; 89(8):3821-9. Wang C, Swerdloff R, Kipnes M, Matsumoto AM, Dobs AS, Cunningham G, Katznelson L, Weber TJ, Friedman TC, Snyder P, Levine HL. PMID: 15292312.
      View in: PubMed   Mentions: 22     Fields:    Translation:HumansCTClinical Trials
    79. Prolactinomas. N Engl J Med. 2004 Mar 04; 350(10):1054-7; author reply 1054-7. Friedman TC. PMID: 14999121.
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    80. Bilateral cerebral aneurysms impinging on the pituitary. Pituitary. 2004; 7(3):193-194. Friedman TC, Shahinian H. PMID: 16328569.
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    81. Acute chagas' disease presenting with a suprasellar mass and panhypopituitarism. Pituitary. 2004; 7(2):111-4. Choi HJ, Cornford M, Wang L, Sun J, Friedman TC. PMID: 15761661.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimals
    82. Leptin activation of corticosterone production in hepatocytes may contribute to the reversal of obesity and hyperglycemia in leptin-deficient ob/ob mice. Diabetes. 2003 Jun; 52(6):1409-16. Liu Y, Nakagawa Y, Wang Y, Li R, Li X, Ohzeki T, Friedman TC. PMID: 12765951.
      View in: PubMed   Mentions: 21     Fields:    Translation:AnimalsCells
    83. Prohormone convertase 2 enzymatic activity and its regulation in neuro-endocrine cells and tissues. Regul Pept. 2003 Feb 28; 110(3):197-205. Li QL, Naqvi S, Shen X, Liu YJ, Lindberg I, Friedman TC. PMID: 12573800.
      View in: PubMed   Mentions: 5     Fields:    Translation:AnimalsCells
    84. The role of vitamin D in mild to moderate chronic kidney disease. Trends Endocrinol Metab. 2002 Jul; 13(5):189-94. Friedman TC, Norris KC. PMID: 12185664.
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    85. Androgen supplementation in older women: too much hype, not enough data. J Am Geriatr Soc. 2002 Jun; 50(6):1131-40. Padero MC, Bhasin S, Friedman TC. PMID: 12110078.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
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