Our site is slower due to heavy traffic from automated ’bots’ and AI crawlers. We’re working to fix this. Read more here.

Gregory A Brent

Title(s)Professor, Medicine
SchoolMedicine
vCardDownload vCard

    Collapse Research 
    Collapse research activities and funding
    Thyroid Hormone Receptor Isoform-Specific Actions
    NIH R01DK098576May 1, 2014 - Feb 28, 2019
    Role: Principal Investigator
    Thyroid Hormone and Neuronal Protection
    NIH I01BX001966Jan 1, 2014 - Mar 31, 2023
    Role: Principal Investigator
    Thyroid Hormone Receptor Isoform-Specific Actions
    NIH R01DK067233Mar 1, 2004 - Feb 28, 2010
    Role: Principal Investigator
    Regulation of the Sodium/Iodide Symporter in Breast
    NIH R01CA089364Jan 12, 2001 - Apr 30, 2013
    Role: Principal Investigator
    ANIMAL AND CELLULAR MODELS OF THYROID HORMONE RESISTANCE
    NIH R01DK043714Feb 1, 1992 - Apr 30, 2001
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
    Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Thyroxine Treatment after Traumatic Brain Injury Suppresses Astrogliosis and Enhances Neuronal Recovery in Mice. Thyroid. 2025 Sep; 35(9):1083-1094. Liu YY, Chen W, Aguiari P, Abe K, Milanesi A, Brent GA. PMID: 40853072.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    2. 2025 American Thyroid Association Management Guidelines for Adult Patients with Differentiated Thyroid Cancer. Thyroid. 2025 Aug; 35(8):841-985. Ringel MD, Sosa JA, Baloch Z, Bischoff L, Bloom G, Brent GA, Brock PL, Chou R, Flavell RR, Goldner W, Grubbs EG, Haymart M, Larson SM, Leung AM, Osborne J, Ridge JA, Robinson B, Steward DL, Tufano RP, Wirth LJ. PMID: 40844370.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    3. Autoimmune Thyroid Disease in the United States: Population Prevalence, Diagnosis Rates, and Trends. J Endocr Soc. 2025 Oct; 9(10):bvaf120. Dillon CF, Weisman MH, Leung AM, Brent GA, Miller FW. PMID: 40980542; PMCID: PMC12449141.
      View in: PubMed   Mentions:
    4. Phosphate Binder Impairs Levothyroxine Absorption in a Hypothyroid Patient With End-Stage Renal Disease. Cureus. 2024 Oct; 16(10):e71551. Ko M, Barai R, Brent G. PMID: 39544577; PMCID: PMC11563566.
      View in: PubMed   Mentions:
    5. Pregnancy-Does Promotion of Growth Extend to Thyroid Cancer? J Clin Endocrinol Metab. 2024 Jun 17; 109(7):e1552-e1553. Leung AM, Brent GA. PMID: 38041866.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    6. A New Twist on a Classic: Enhancing Radioiodine Uptake in Advanced Thyroid Cancer. Clin Cancer Res. 2024 04 01; 30(7):1220-1222. Lechner MG, Brent GA. PMID: 38197869; PMCID: PMC10984766.
      View in: PubMed   Mentions:    Fields:    Translation:Animals
    7. Weighing in on Thyroid Signaling in the Hypothalamus: Mechanisms and Interface with Metabolic Regulators. Thyroid. 2024 02; 34(2):141-143. Milanesi A, Brent GA. PMID: 38269429.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    8. Impact of Thyroid Status on Incident Kidney Dysfunction and Chronic Kidney Disease Progression in a Nationally Representative Cohort. Mayo Clin Proc. 2024 Jan; 99(1):39-56. You AS, Kalantar-Zadeh K, Brent GA, Narasaki Y, Daza A, Sim JJ, Kovesdy CP, Nguyen DV, Rhee CM. PMID: 38176833; PMCID: PMC10795379.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    9. Development and Validation of a Prediction Model for Incident Hypothyroidism in a National Chronic Kidney Disease Cohort. J Clin Endocrinol Metab. 2023 10 18; 108(11):e1374-e1383. Rhee CM, You AS, Narasaki Y, Brent GA, Sim JJ, Kovesdy CP, Kalantar-Zadeh K, Nguyen DV. PMID: 37186674; PMCID: PMC11009786.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    10. A Historical Reflection on Scientific Advances in Understanding Thyroid Hormone Action. Thyroid. 2023 10; 33(10):1140-1149. Brent GA. PMID: 37594753.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimals
    11. Approach to the Patient With a Suppressed TSH. J Clin Endocrinol Metab. 2023 01 17; 108(2):472-482. Praw SS, Brent GA. PMID: 36329632.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    12. Thyroid Hormone-mediated Histone Modification Protects Cortical Neurons From the Toxic Effects of Hypoxic Injury. J Endocr Soc. 2022 Oct 11; 6(11):bvac139. Abe K, Li J, Liu YY, Brent GA. PMID: 36817622; PMCID: PMC9562813.
      View in: PubMed   Mentions: 5  
    13. Serum Thyrotropin Elevation and Coronary Artery Calcification in Hemodialysis Patients. Cardiorenal Med. 2022; 12(3):106-116. Rhee CM, Budoff M, Brent G, You AS, Stenvinkel P, Novoa A, Flores F, Hamal S, Dailing C, Kinninger A, Nakata T, Kovesdy CP, Nguyen DV, Kalantar-Zadeh K. PMID: 35551382; PMCID: PMC9452456.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    14. Serum Thyroglobulin Measurement Following Surgery Without Radioactive Iodine for Differentiated Thyroid Cancer: A Systematic Review. Thyroid. 2022 06; 32(6):613-639. Chou R, Dana T, Brent GA, Goldner W, Haymart M, Leung AM, Ringel MD, Sosa JA. PMID: 35412871; PMCID: PMC11265617.
      View in: PubMed   Mentions: 25     Fields:    Translation:Humans
    15. Thyroid hormone receptor alpha sumoylation modulates white adipose tissue stores. Sci Rep. 2021 12 16; 11(1):24105. Liu YY, Jiang J, Ke S, Milanesi A, Abe K, Gastelum G, Li J, Brent GA. PMID: 34916557; PMCID: PMC8677787.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimalsCells
    16. Thyroid hormone receptor β sumoylation is required for thyrotropin regulation and thyroid hormone production. JCI Insight. 2021 08 23; 6(16). Ke S, Liu YY, Karthikraj R, Kannan K, Jiang J, Abe K, Milanesi A, Brent GA. PMID: 34237030; PMCID: PMC8410017.
      View in: PubMed   Mentions: 4     Fields:    Translation:AnimalsCells
    17. Elevated serum thyrotropin levels and endothelial dysfunction in a prospective hemodialysis cohort. Hemodial Int. 2022 01; 26(1):57-65. You AS, Budoff M, Zeb I, Ahmadi N, Novoa A, Flores F, Hamal S, Kinninger A, Dailing C, Nakata T, Kovesdy CP, Nguyen DV, Brent GA, Kalantar-Zadeh K, Rhee CM. PMID: 34231302; PMCID: PMC10753993.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    18. The Role of Thyroid Hormone in Neuronal Protection. Compr Physiol. 2021 06 01; 11(3):2075-2095. Liu YY, Brent GA. PMID: 34061976.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansAnimals
    19. Persistent COUP-TFII expression underlies the myopathy and impaired muscle regeneration observed in resistance to thyroid hormone-alpha. Sci Rep. 2021 02 25; 11(1):4601. Aguiari P, Liu YY, Petrosyan A, Cheng SY, Brent GA, Perin L, Milanesi A. PMID: 33633251; PMCID: PMC7907286.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    20. Association of Subclinical Hypothyroidism and Cardiovascular Disease With Mortality. JAMA Netw Open. 2020 02 05; 3(2):e1920745. Inoue K, Ritz B, Brent GA, Ebrahimi R, Rhee CM, Leung AM. PMID: 32031647; PMCID: PMC12064075.
      View in: PubMed   Mentions: 87     Fields:    Translation:Humans
    21. Association of thyroid status prior to transition to end-stage renal disease with early dialysis mortality. Nephrol Dial Transplant. 2019 12 01; 34(12):2095-2104. You AS, Sim JJ, Kovesdy CP, Streja E, Nguyen DV, Brent GA, Kalantar-Zadeh K, Rhee CM. PMID: 30299498; PMCID: PMC6887739.
      View in: PubMed   Mentions: 11     Fields:    Translation:Humans
    22. Thyroid Hormone Protects Primary Cortical Neurons Exposed to Hypoxia by Reducing DNA Methylation and Apoptosis. Endocrinology. 2019 10 01; 160(10):2243-2256. Li J, Abe K, Milanesi A, Liu YY, Brent GA. PMID: 31095291.
      View in: PubMed   Mentions: 17     Fields:    Translation:AnimalsCells
    23. Older Adults with Cognitive Impairment Have Sex: More Evidence Against the Medical Myth of Sexless Aging. J Am Geriatr Soc. 2018 10; 66(10):1870-1871. Granville L, Brent GA, Pregler J. PMID: 30207596.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    24. Thyroid Status and Death Risk in US Veterans With Chronic Kidney Disease. Mayo Clin Proc. 2018 05; 93(5):573-585. Rhee CM, Kalantar-Zadeh K, Ravel V, Streja E, You AS, Brunelli SM, Nguyen DV, Brent GA, Kovesdy CP. PMID: 29728200; PMCID: PMC6049829.
      View in: PubMed   Mentions: 17     Fields:    Translation:Humans
    25. Thyroid hormone and the brain: Mechanisms of action in development and role in protection and promotion of recovery after brain injury. Pharmacol Ther. 2018 06; 186:176-185. Liu YY, Brent GA. PMID: 29378220; PMCID: PMC5962384.
      View in: PubMed   Mentions: 41     Fields:    Translation:HumansAnimalsCells
    26. COUP-TF1 Modulates Thyroid Hormone Action in an Embryonic Stem-Cell Model of Cortical Pyramidal Neuronal Differentiation. Thyroid. 2018 05; 28(5):667-678. Teng X, Liu YY, Teng W, Brent GA. PMID: 29205104; PMCID: PMC5952340.
      View in: PubMed   Mentions: 7     Fields:    Translation:AnimalsCells
    27. Posttranslational Modification of Thyroid Hormone Nuclear Receptor by Phosphorylation. Methods Mol Biol. 2018; 1801:39-46. Liu YY, Brent GA. PMID: 29892815.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansAnimalsCells
    28. Posttranslational Modification of Thyroid Hormone Nuclear Receptor by Sumoylation. Methods Mol Biol. 2018; 1801:47-59. Liu YY, Brent GA. PMID: 29892816.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansAnimalsCells
    29. Thyroid Hormone Receptor Alpha is Essential to Maintain the Satellite Cell Niche During Skeletal Muscle Injury and Sarcopenia of Aging. Thyroid. 2017 10; 27(10):1316-1322. Milanesi A, Lee JW, Yang A, Liu YY, Sedrakyan S, Cheng SY, Perin L, Brent GA. PMID: 28847239; PMCID: PMC5649408.
      View in: PubMed   Mentions: 20     Fields:    Translation:AnimalsCells
    30. Thyroid Status, Quality of Life, and Mental Health in Patients on Hemodialysis. Clin J Am Soc Nephrol. 2017 Aug 07; 12(8):1274-1283. Rhee CM, Chen Y, You AS, Brunelli SM, Kovesdy CP, Budoff MJ, Brent GA, Kalantar-Zadeh K, Nguyen DV. PMID: 28705886; PMCID: PMC5544520.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansCells
    31. Association of Glycemic Status During Progression of Chronic Kidney Disease With Early Dialysis Mortality in Patients With Diabetes. Diabetes Care. 2017 08; 40(8):1050-1057. Rhee CM, Kovesdy CP, Ravel VA, Streja E, Brunelli SM, Soohoo M, Sumida K, Molnar MZ, Brent GA, Nguyen DV, Kalantar-Zadeh K. PMID: 28592525; PMCID: PMC5521972.
      View in: PubMed   Mentions: 13     Fields:    Translation:Humans
    32. Thyroid hormone treatment activates protective pathways in both in vivo and in vitro models of neuronal injury. Mol Cell Endocrinol. 2017 09 05; 452:120-130. Li J, Donangelo I, Abe K, Scremin O, Ke S, Li F, Milanesi A, Liu YY, Brent GA. PMID: 28549992.
      View in: PubMed   Mentions: 26     Fields:    Translation:HumansAnimalsCells
    33. Thyroid Status and Mortality in a Prospective Hemodialysis Cohort. J Clin Endocrinol Metab. 2017 05 01; 102(5):1568-1577. Rhee CM, You AS, Nguyen DV, Brunelli SM, Budoff MJ, Streja E, Nakata T, Kovesdy CP, Brent GA, Kalantar-Zadeh K. PMID: 28324018; PMCID: PMC5443328.
      View in: PubMed   Mentions: 25     Fields:    Translation:Humans
    34. Beam Me In: Thyroid Hormone Analog Targets Alternative Transporter in Mouse Model of X-Linked Adrenoleukodystrophy Endocrinology. 2017 04 29; 158(5):1116-1119. Milanesi A, Brent GA. PMID: 28609836; PMCID: PMC5460838.
      View in: PubMed   Mentions: 1     Fields:    
    35. 2017 Guidelines of the American Thyroid Association for the Diagnosis and Management of Thyroid Disease During Pregnancy and the Postpartum. Thyroid. 2017 03; 27(3):315-389. Alexander EK, Pearce EN, Brent GA, Brown RS, Chen H, Dosiou C, Grobman WA, Laurberg P, Lazarus JH, Mandel SJ, Peeters RP, Sullivan S. PMID: 28056690.
      View in: PubMed   Mentions: 891     Fields:    Translation:Humans
    36. Thyroid Functional Disease and Mortality in a National Peritoneal Dialysis Cohort. J Clin Endocrinol Metab. 2016 11; 101(11):4054-4061. Rhee CM, Ravel VA, Streja E, Mehrotra R, Kim S, Wang J, Nguyen DV, Kovesdy CP, Brent GA, Kalantar-Zadeh K. PMID: 27525529; PMCID: PMC5095247.
      View in: PubMed   Mentions: 19     Fields:    Translation:Humans
    37. Exposure to Thyroid-Disrupting Chemicals: A Transatlantic Call for Action. Thyroid. 2016 Apr; 26(4):479-80. Leung AM, Korevaar TI, Peeters RP, Zoeller RT, Köhrle J, Duntas LH, Brent GA, Demeneix BA. PMID: 26906244; PMCID: PMC4827314.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansPHPublic Health
    38. Thyroid Hormone Receptor α Plays an Essential Role in Male Skeletal Muscle Myoblast Proliferation, Differentiation, and Response to Injury. Endocrinology. 2016 Jan; 157(1):4-15. Milanesi A, Lee JW, Kim NH, Liu YY, Yang A, Sedrakyan S, Kahng A, Cervantes V, Tripuraneni N, Cheng SY, Perin L, Brent GA. PMID: 26451739; PMCID: PMC4701883.
      View in: PubMed   Mentions: 30     Fields:    Translation:AnimalsCells
    39. A Patient With a Thyrotropin-Secreting Microadenoma and Resistance to Thyroid Hormone (P453T). J Clin Endocrinol Metab. 2015 Jul; 100(7):2511-4. Teng X, Jin T, Brent GA, Wu A, Teng W, Shan Z. PMID: 25867808; PMCID: PMC5393528.
      View in: PubMed   Mentions: 25     Fields:    Translation:Humans
    40. Association of Adiponectin With Body Composition and Mortality in Hemodialysis Patients. Am J Kidney Dis. 2015 Aug; 66(2):313-21. Rhee CM, Nguyen DV, Moradi H, Brunelli SM, Dukkipati R, Jing J, Nakata T, Kovesdy CP, Brent GA, Kalantar-Zadeh K. PMID: 25824125; PMCID: PMC4516594.
      View in: PubMed   Mentions: 33     Fields:    Translation:Humans
    41. Association of thyroid functional disease with mortality in a national cohort of incident hemodialysis patients. J Clin Endocrinol Metab. 2015 Apr; 100(4):1386-95. Rhee CM, Kim S, Gillen DL, Oztan T, Wang J, Mehrotra R, Kuttykrishnan S, Nguyen DV, Brunelli SM, Kovesdy CP, Brent GA, Kalantar-Zadeh K. PMID: 25632971; PMCID: PMC4399303.
      View in: PubMed   Mentions: 39     Fields:    Translation:Humans
    42. Thyroid hormone receptor sumoylation is required for preadipocyte differentiation and proliferation. J Biol Chem. 2015 Mar 20; 290(12):7402-15. Liu YY, Ayers S, Milanesi A, Teng X, Rabi S, Akiba Y, Brent GA. PMID: 25572392; PMCID: PMC4367250.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansCells
    43. Thyrotoxicosis of Pregnancy. J Clin Transl Endocrinol. 2014 Dec 01; 1(4):140-144. Labadzhyan A, Brent GA, Hershman JM, Leung AM. PMID: 25243108; PMCID: PMC4166486.
      View in: PubMed   Mentions: 10  
    44. A review: Radiographic iodinated contrast media-induced thyroid dysfunction. J Clin Endocrinol Metab. 2015 Feb; 100(2):376-83. Lee SY, Rhee CM, Leung AM, Braverman LE, Brent GA, Pearce EN. PMID: 25375985; PMCID: PMC4318903.
      View in: PubMed   Mentions: 80     Fields:    Translation:Humans
    45. Perchlorate exposure in pregnancy and cognitive outcomes in children: it's not your mother's thyroid. J Clin Endocrinol Metab. 2014 Nov; 99(11):4066-8. Brent GA. PMID: 25372124; PMCID: PMC4223440.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    46. Thyroid hormone regulation of metabolism. Physiol Rev. 2014 Apr; 94(2):355-82. Mullur R, Liu YY, Brent GA. PMID: 24692351; PMCID: PMC4044302.
      View in: PubMed   Mentions: 857     Fields:    Translation:HumansAnimalsCells
    47. Classification and proposed nomenclature for inherited defects of thyroid hormone action, cell transport, and metabolism. Eur Thyroid J. 2014 Mar; 3(1):7-9. Refetoff S, Bassett JH, Beck-Peccoz P, Bernal J, Brent G, Chatterjee K, De Groot LJ, Dumitrescu AM, Jameson JL, Kopp PA, Murata Y, Persani L, Samarut J, Weiss RE, Williams GR, Yen PM. PMID: 24847459; PMCID: PMC4005262.
      View in: PubMed   Mentions: 13     Fields:    
    48. Classification and proposed nomenclature for inherited defects of thyroid hormone action, cell transport, and metabolism. Thyroid. 2014 Mar; 24(3):407-9. Refetoff S, Bassett JH, Beck-Peccoz P, Bernal J, Brent G, Chatterjee K, De Groot LJ, Dumitrescu AM, Jameson JL, Kopp PA, Murata Y, Persani L, Samarut J, Weiss RE, Williams GR, Yen PM. PMID: 24588711; PMCID: PMC3950730.
      View in: PubMed   Mentions: 16     Fields:    Translation:Humans
    49. Updates on the management of diabetes in dialysis patients. Semin Dial. 2014 Mar; 27(2):135-45. Rhee CM, Leung AM, Kovesdy CP, Lynch KE, Brent GA, Kalantar-Zadeh K. PMID: 24588802; PMCID: PMC3960718.
      View in: PubMed   Mentions: 54     Fields:    Translation:Humans
    50. Classification and proposed nomenclature for inherited defects of thyroid hormone action, cell transport, and metabolism. J Clin Endocrinol Metab. 2014 Mar; 99(3):768-70. Refetoff S, Bassett JH, Beck-Peccoz P, Bernal J, Brent G, Chatterjee K, De Groot LJ, Dumitrescu AM, Jameson JL, Kopp PA, Murata Y, Persani L, Samarut J, Weiss RE, Williams GR, Yen PM. PMID: 24823702; PMCID: PMC3942236.
      View in: PubMed   Mentions: 24     Fields:    Translation:Humans
    51. Thyroid functional disease: an under-recognized cardiovascular risk factor in kidney disease patients. Nephrol Dial Transplant. 2015 May; 30(5):724-37. Rhee CM, Brent GA, Kovesdy CP, Soldin OP, Nguyen D, Budoff MJ, Brunelli SM, Kalantar-Zadeh K. PMID: 24574542; PMCID: PMC4425477.
      View in: PubMed   Mentions: 50     Fields:    Translation:HumansAnimals
    52. Commentary on: "American Thyroid Association Guide to investigating thyroid hormone economy and action in rodent and cell models," Bianco et al. Thyroid. 2014 Jan; 24(1):1-2. Brent GA. PMID: 24303889; PMCID: PMC3887401.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimals
    53. Children of mothers with iodine deficiency during pregnancy are more likely to have lower verbal IQ and reading scores at 8-9 years of age. Evid Based Nurs. 2014 Jul; 17(3):86. Leung AM, Brent GA. PMID: 24336752; PMCID: PMC4055540.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    54. Cancer: Novel target to enhance radioiodine uptake in thyroid cancer. Nat Rev Endocrinol. 2013 Sep; 9(9):508-9. Brent GA, Kogai T. PMID: 23817292.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimalsCells
    55. Mechanisms of thyroid hormone action. J Clin Invest. 2012 Sep; 122(9):3035-43. Brent GA. PMID: 22945636; PMCID: PMC3433956.
      View in: PubMed   Mentions: 451     Fields:    Translation:HumansAnimalsCells
    56. Thyroid hormone receptor isoform-specific modification by small ubiquitin-like modifier (SUMO) modulates thyroid hormone-dependent gene regulation. J Biol Chem. 2012 Oct 19; 287(43):36499-508. Liu YY, Kogai T, Schultz JJ, Mody K, Brent GA. PMID: 22930759; PMCID: PMC3476315.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansAnimalsCells
    57. The sodium iodide symporter (NIS): regulation and approaches to targeting for cancer therapeutics. Pharmacol Ther. 2012 Sep; 135(3):355-70. Kogai T, Brent GA. PMID: 22750642; PMCID: PMC3408573.
      View in: PubMed   Mentions: 88     Fields:    Translation:HumansAnimalsCells
    58. The debate over thyroid-function screening in pregnancy. N Engl J Med. 2012 Feb 09; 366(6):562-3. Brent GA. PMID: 22316450.
      View in: PubMed   Mentions: 17     Fields:    Translation:Humans
    59. Regulation of sodium iodide symporter gene expression by Rac1/p38β mitogen-activated protein kinase signaling pathway in MCF-7 breast cancer cells. J Biol Chem. 2012 Jan 27; 287(5):3292-300. Kogai T, Liu YY, Mody K, Shamsian DV, Brent GA. PMID: 22157753; PMCID: PMC3270984.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansAnimalsCells
    60. Management of hypothyroidism in pregnancy. Curr Opin Endocrinol Diabetes Obes. 2011 Oct; 18(5):304-9. Milanesi A, Brent GA. PMID: 21841481.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    61. Publication of industry-sponsored medical research: guidelines from the Consortium of Laboratory Medicine Journal Editors. Thyroid. 2011 Jul; 21(7):693. Soldin OP, Brent GA, Kloos RT. PMID: 21707435.
      View in: PubMed   Mentions:    Fields:    
    62. Thyroid hormone and COUP-TF1 regulate kallikrein-binding protein (KBP) gene expression. Endocrinology. 2011 Mar; 152(3):1143-53. Liu YY, Nakatani T, Kogai T, Mody K, Brent GA. PMID: 21266512; PMCID: PMC3040047.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimalsCells
    63. Environmental exposures and autoimmune thyroid disease. Thyroid. 2010 Jul; 20(7):755-61. Brent GA. PMID: 20578899; PMCID: PMC2935336.
      View in: PubMed   Mentions: 55     Fields:    Translation:HumansAnimalsPHPublic Health
    64. The impact of perchlorate exposure in early pregnancy: is it safe to drink the water? J Clin Endocrinol Metab. 2010 Jul; 95(7):3154-7. Brent GA. PMID: 20610607; PMCID: PMC2928898.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansPHPublic Health
    65. Retinoic acid induces expression of the thyroid hormone transporter, monocarboxylate transporter 8 (Mct8). J Biol Chem. 2010 Aug 27; 285(35):27279-27288. Kogai T, Liu YY, Richter LL, Mody K, Kagechika H, Brent GA. PMID: 20573951; PMCID: PMC2930727.
      View in: PubMed   Mentions: 16     Fields:    Translation:AnimalsCells
    66. Thyroid hormone crosstalk with nuclear receptor signaling in metabolic regulation. Trends Endocrinol Metab. 2010 Mar; 21(3):166-73. Liu YY, Brent GA. PMID: 20015660; PMCID: PMC2831161.
      View in: PubMed   Mentions: 85     Fields:    Translation:HumansAnimalsCells
    67. Expression of uncoupling protein 1 in mouse brown adipose tissue is thyroid hormone receptor-beta isoform specific and required for adaptive thermogenesis. Endocrinology. 2010 Jan; 151(1):432-40. Ribeiro MO, Bianco SD, Kaneshige M, Schultz JJ, Cheng SY, Bianco AC, Brent GA. PMID: 19906816; PMCID: PMC2817565.
      View in: PubMed   Mentions: 54     Fields:    Translation:AnimalsCells
    68. Activation of the PI3 kinase pathway by retinoic acid mediates sodium/iodide symporter induction and iodide transport in MCF-7 breast cancer cells. Cancer Res. 2009 Apr 15; 69(8):3443-50. Ohashi E, Kogai T, Kagechika H, Brent GA. PMID: 19351850; PMCID: PMC2852426.
      View in: PubMed   Mentions: 21     Fields:    Translation:HumansAnimalsCells
    69. Phosphoinositide-3-kinase inhibition induces sodium/iodide symporter expression in rat thyroid cells and human papillary thyroid cancer cells. J Endocrinol. 2008 Nov; 199(2):243-52. Kogai T, Sajid-Crockett S, Newmarch LS, Liu YY, Brent GA. PMID: 18762555.
      View in: PubMed   Mentions: 54     Fields:    Translation:HumansAnimalsCells
    70. Clinical practice. Graves' disease. N Engl J Med. 2008 Jun 12; 358(24):2594-605. Brent GA. PMID: 18550875.
      View in: PubMed   Mentions: 188     Fields:    Translation:Humans
    71. Stealth sequences in reporter gene vectors confound studies of T3-regulated negative gene expression. Thyroid. 2008 Jun; 18(6):593-5. Liu YY, Brent GA. PMID: 18578606.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimalsCells
    72. Retinoic acid stimulation of the sodium/iodide symporter in MCF-7 breast cancer cells is mediated by the insulin growth factor-I/phosphatidylinositol 3-kinase and p38 mitogen-activated protein kinase signaling pathways. J Clin Endocrinol Metab. 2008 May; 93(5):1884-92. Kogai T, Ohashi E, Jacobs MS, Sajid-Crockett S, Fisher ML, Kanamoto Y, Brent GA. PMID: 18319322; PMCID: PMC2386284.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansCells
    73. Thyroid health and the environment. Thyroid. 2007 Sep; 17(9):807-9. Brent GA, Braverman LE, Zoeller RT. PMID: 17956154.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansPHPublic Health
    74. Diagnosing thyroid dysfunction in pregnant women: Is case finding enough? J Clin Endocrinol Metab. 2007 Jan; 92(1):39-41. Brent GA. PMID: 17209222.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    75. Thyroid hormone regulates endogenous amyloid-beta precursor protein gene expression and processing in both in vitro and in vivo models. Thyroid. 2006 Dec; 16(12):1207-13. O'Barr SA, Oh JS, Ma C, Brent GA, Schultz JJ. PMID: 17199430.
      View in: PubMed   Mentions: 24     Fields:    Translation:HumansAnimalsCells
    76. A mutant thyroid hormone receptor alpha antagonizes peroxisome proliferator-activated receptor alpha signaling in vivo and impairs fatty acid oxidation. Endocrinology. 2007 Mar; 148(3):1206-17. Liu YY, Heymann RS, Moatamed F, Schultz JJ, Sobel D, Brent GA. PMID: 17122078.
      View in: PubMed   Mentions: 36     Fields:    Translation:AnimalsCells
    77. Anaplastic thyroid carcinoma with thyrotoxicosis and hypoparathyroidism. Endocr Pract. 2005 Jul-Aug; 11(4):281-4. Heymann RS, Brent GA, Hershman JM. PMID: 16006301.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    78. Differential regulation of sodium/iodide symporter gene expression by nuclear receptor ligands in MCF-7 breast cancer cells. Endocrinology. 2005 Jul; 146(7):3059-69. Kogai T, Kanamoto Y, Li AI, Che LH, Ohashi E, Taki K, Chandraratna RA, Saito T, Brent GA. PMID: 15817668.
      View in: PubMed   Mentions: 22     Fields:    Translation:HumansCells
    79. Rapid progression from subclinical to symptomatic overt hypothyroidism. Endocr Pract. 2005 Mar-Apr; 11(2):115-9. Heymann R, Brent GA. PMID: 15901527.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    80. Resistance to thyroid hormone in Hashimoto's thyroiditis. N Engl J Med. 2005 Feb 03; 352(5):517-8. Fukata S, Brent GA, Sugawara M. PMID: 15689599.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    81. Introduction. The impact of maternal thyroid diseases on the developing fetus: implications for diagnosis, treatment, and screening. Summary of proceedings, workshop organization, program, and participants. Thyroid. 2005 Jan; 15(1):36-40. Brent G, Boyle CA. PMID: 15687821.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    82. Regulation of regional expression in rat brain PC2 by thyroid hormone/characterization of novel negative thyroid hormone response elements in the PC2 promoter. Am J Physiol Endocrinol Metab. 2005 Jan; 288(1):E236-45. Shen X, Li QL, Brent GA, Friedman TC. PMID: 15585599.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    83. Thyroid function inside and outside of pregnancy: what do we know and what don't we know? Thyroid. 2005 Jan; 15(1):54-9. Smallridge RC, Glinoer D, Hollowell JG, Brent G. PMID: 15687824.
      View in: PubMed   Mentions: 17     Fields:    Translation:Humans
    84. Thyroid hormone-dependent gene expression in differentiated embryonic stem cells and embryonal carcinoma cells: identification of novel thyroid hormone target genes by deoxyribonucleic acid microarray analysis. Endocrinology. 2005 Feb; 146(2):776-83. Liu YY, Brent GA. PMID: 15550503.
      View in: PubMed   Mentions: 8     Fields:    Translation:AnimalsCells
    85. Systemic retinoic acid treatment induces sodium/iodide symporter expression and radioiodide uptake in mouse breast cancer models. Cancer Res. 2004 Jan 01; 64(1):415-22. Kogai T, Kanamoto Y, Che LH, Taki K, Moatamed F, Schultz JJ, Brent GA. PMID: 14729653.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansAnimalsCells
    86. Enhanced expression of nicotinamide N-methyltransferase in human papillary thyroid carcinoma cells. J Clin Endocrinol Metab. 2003 Oct; 88(10):4990-6. Xu J, Moatamed F, Caldwell JS, Walker JR, Kraiem Z, Taki K, Brent GA, Hershman JM. PMID: 14557485.
      View in: PubMed   Mentions: 37     Fields:    Translation:HumansCells
    87. Spared bone mass in rats treated with thyroid hormone receptor TR beta-selective compound GC-1. Am J Physiol Endocrinol Metab. 2003 Nov; 285(5):E1135-41. Freitas FR, Moriscot AS, Jorgetti V, Soares AG, Passarelli M, Scanlan TS, Brent GA, Bianco AC, Gouveia CH. PMID: 12965872.
      View in: PubMed   Mentions: 23     Fields:    Translation:Animals
    88. Follow-up of newborns with elevated screening T4 concentrations. J Pediatr. 2003 Sep; 143(3):296-301. Lafranchi SH, Snyder DB, Sesser DE, Skeels MR, Singh N, Brent GA, Nelson JC. PMID: 14517508.
      View in: PubMed   Mentions: 50     Fields:    Translation:HumansPHPublic Health
    89. Nonradioactive iodide effectively induces apoptosis in genetically modified lung cancer cells. Cancer Res. 2003 Aug 15; 63(16):5065-72. Zhang L, Sharma S, Zhu LX, Kogai T, Hershman JM, Brent GA, Dubinett SM, Huang M. PMID: 12941836.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansAnimalsCells
    90. A thyroid hormone receptor alpha gene mutation (P398H) is associated with visceral adiposity and impaired catecholamine-stimulated lipolysis in mice. J Biol Chem. 2003 Oct 03; 278(40):38913-20. Liu YY, Schultz JJ, Brent GA. PMID: 12869545.
      View in: PubMed   Mentions: 53     Fields:    Translation:AnimalsCells
    91. The modified firefly luciferase reporter gene (luc+) but not Renilla luciferase is induced by all-trans retinoic acid in MCF-7 breast cancer cells. Breast Cancer Res Treat. 2003 Mar; 78(1):119-26. Kogai T, Kanamoto Y, Brent GA. PMID: 12611464.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansAnimalsCells
    92. A complex deoxyribonucleic acid response element in the rat Ca(2+)/calmodulin-dependent protein kinase IV gene 5'-flanking region mediates thyroid hormone induction and chicken ovalbumin upstream promoter transcription factor 1 repression. Mol Endocrinol. 2002 Nov; 16(11):2439-51. Liu YY, Brent GA. PMID: 12403833.
      View in: PubMed   Mentions: 16     Fields:    Translation:AnimalsCells
    93. A thyroid-specific far-upstream enhancer in the human sodium/iodide symporter gene requires Pax-8 binding and cyclic adenosine 3',5'-monophosphate response element-like sequence binding proteins for full activity and is differentially regulated in normal and thyroid cancer cells. Mol Endocrinol. 2002 Oct; 16(10):2266-82. Taki K, Kogai T, Kanamoto Y, Hershman JM, Brent GA. PMID: 12351692.
      View in: PubMed   Mentions: 36     Fields:    Translation:HumansAnimalsCells
    94. Thyroid hormone gene targets in ROS 17/2.8 osteoblast-like cells identified by differential display analysis. Thyroid. 2002 Aug; 12(8):663-71. Gouveia CH, Schultz JJ, Jackson DJ, Williams GR, Brent GA. PMID: 12225634.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    95. A targeted thyroid hormone receptor alpha gene dominant-negative mutation (P398H) selectively impairs gene expression in differentiated embryonic stem cells. Endocrinology. 2002 Jul; 143(7):2664-72. Liu YY, Tachiki KH, Brent GA. PMID: 12072400.
      View in: PubMed   Mentions: 13     Fields:    Translation:AnimalsCells
    96. Nonthyroidal illness syndrome: evaluation of thyroid function in sick patients. Endocrinol Metab Clin North Am. 2002 Mar; 31(1):159-72. Langton JE, Brent GA. PMID: 12055987.
      View in: PubMed   Mentions: 21     Fields:    Translation:Humans
    97. A GC box in the human sodium iodide symporter gene promoter is essential for full activity. Thyroid. 2002 Feb; 12(2):107-14. Xu J, Kogai T, Brent GA, Hershman JM. PMID: 11916279.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimalsCells
    98. The Kaposi sarcoma-associated herpesvirus (KSHV) induces cellular interleukin 6 expression: role of the KSHV latency-associated nuclear antigen and the AP1 response element. Blood. 2002 Jan 15; 99(2):649-54. An J, Lichtenstein AK, Brent G, Rettig MB. PMID: 11781250.
      View in: PubMed   Mentions: 52     Fields:    Translation:HumansCells
    Gregory's Networks
    Concepts (445)
    Derived automatically from this person's publications.
    Explore
    _
    Co-Authors (25)
    People in Profiles who have published with this person.
    Explore
    _
    Similar People (60)
    People who share similar concepts with this person.
    Explore
    _
    Same Department
    Search Department
    _

    UCLA Profiles is managed by the UCSF Clinical and Translational Science Institute (CTSI), part of the Clinical and Translational Science Award program funded by the National Center for Advancing Translational Sciences (Grant Number UL1 TR000004) at the National Institutes of Health (NIH).
    This site is running Profiles RNS version UCSF-v3.1.0-16-gff1bd585 on PROFILES-PWEB03. We use cookies to operate our website. We also use cookies to analyze our site’s performance and improve your experience on our site. For more information about how we use cookies, please see our Website Terms of Use.

    Copyright © The Regents of the University of California