Gregory A Brent

Title(s)Department Vice Chair, Medicine Dept.
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    Other Positions
    Title(s)Professor, Medicine

    Title(s)Professor, Physiology

    Collapse Research 
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    Thyroid Hormone Receptor Isoform-Specific Actions
    NIH R01DK098576May 1, 2014 - Feb 28, 2019
    Role: Principal Investigator
    Thyroid Hormone and Neuronal Protection
    NIH I01BX001966Jan 1, 2014 - Mar 31, 2023
    Role: Principal Investigator
    Thyroid Hormone Receptor Isoform-Specific Actions
    NIH R01DK067233Mar 1, 2004 - Feb 28, 2010
    Role: Principal Investigator
    Regulation of the Sodium/Iodide Symporter in Breast
    NIH R01CA089364Jan 12, 2001 - Apr 30, 2013
    Role: Principal Investigator
    NIH R01DK043714Feb 1, 1992 - Apr 30, 2001
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. A New Twist on a Classic: Enhancing Radioiodine Uptake in Advanced Thyroid Cancer. Clin Cancer Res. 2024 Apr 01; 30(7):1220-1222. Lechner MG, Brent GA. PMID: 38197869; PMCID: PMC10984766.
      View in: PubMed   Mentions:    Fields:    
    2. Weighing in on Thyroid Signaling in the Hypothalamus: Mechanisms and Interface with Metabolic Regulators. Thyroid. 2024 Feb; 34(2):141-143. Milanesi A, Brent GA. PMID: 38269429.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    3. Impact of Thyroid Status on Incident Kidney Dysfunction and Chronic Kidney Disease Progression in a Nationally Representative Cohort. Mayo Clin Proc. 2024 Jan; 99(1):39-56. You AS, Kalantar-Zadeh K, Brent GA, Narasaki Y, Daza A, Sim JJ, Kovesdy CP, Nguyen DV, Rhee CM. PMID: 38176833; PMCID: PMC10795379.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    4. Pregnancy - Does Promotion of Growth Extend to Thyroid Cancer? J Clin Endocrinol Metab. 2023 Dec 02. Leung AM, Brent GA. PMID: 38041866.
      View in: PubMed   Mentions:    Fields:    
    5. Development and Validation of a Prediction Model for Incident Hypothyroidism in a National Chronic Kidney Disease Cohort. J Clin Endocrinol Metab. 2023 10 18; 108(11):e1374-e1383. Rhee CM, You AS, Narasaki Y, Brent GA, Sim JJ, Kovesdy CP, Kalantar-Zadeh K, Nguyen DV. PMID: 37186674; PMCID: PMC11009786.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    6. A Historical Reflection on Scientific Advances in Understanding Thyroid Hormone Action. Thyroid. 2023 Oct; 33(10):1140-1149. Brent GA. PMID: 37594753.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimals
    7. Approach to the Patient With a Suppressed TSH. J Clin Endocrinol Metab. 2023 01 17; 108(2):472-482. Praw SS, Brent GA. PMID: 36329632.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    8. Thyroid Hormone-mediated Histone Modification Protects Cortical Neurons From the Toxic Effects of Hypoxic Injury. J Endocr Soc. 2022 Oct 11; 6(11):bvac139. Abe K, Li J, Liu YY, Brent GA. PMID: 36817622; PMCID: PMC9562813.
      View in: PubMed   Mentions: 3  
    9. Serum Thyrotropin Elevation and Coronary Artery Calcification in Hemodialysis Patients. Cardiorenal Med. 2022; 12(3):106-116. Rhee CM, Budoff M, Brent G, You AS, Stenvinkel P, Novoa A, Flores F, Hamal S, Dailing C, Kinninger A, Nakata T, Kovesdy CP, Nguyen DV, Kalantar-Zadeh K. PMID: 35551382; PMCID: PMC9452456.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    10. Serum Thyroglobulin Measurement Following Surgery Without Radioactive Iodine for Differentiated Thyroid Cancer: A Systematic Review. Thyroid. 2022 06; 32(6):613-639. Chou R, Dana T, Brent GA, Goldner W, Haymart M, Leung AM, Ringel MD, Sosa JA. PMID: 35412871.
      View in: PubMed   Mentions: 12     Fields:    Translation:Humans
    11. Thyroid hormone receptor alpha sumoylation modulates white adipose tissue stores. Sci Rep. 2021 12 16; 11(1):24105. Liu YY, Jiang J, Ke S, Milanesi A, Abe K, Gastelum G, Li J, Brent GA. PMID: 34916557; PMCID: PMC8677787.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    12. Thyroid hormone receptor β sumoylation is required for thyrotropin regulation and thyroid hormone production. JCI Insight. 2021 08 23; 6(16). Ke S, Liu YY, Karthikraj R, Kannan K, Jiang J, Abe K, Milanesi A, Brent GA. PMID: 34237030; PMCID: PMC8410017.
      View in: PubMed   Mentions: 4     Fields:    Translation:AnimalsCells
    13. Elevated serum thyrotropin levels and endothelial dysfunction in a prospective hemodialysis cohort. Hemodial Int. 2022 01; 26(1):57-65. You AS, Budoff M, Zeb I, Ahmadi N, Novoa A, Flores F, Hamal S, Kinninger A, Dailing C, Nakata T, Kovesdy CP, Nguyen DV, Brent GA, Kalantar-Zadeh K, Rhee CM. PMID: 34231302; PMCID: PMC10753993.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    14. The Role of Thyroid Hormone in Neuronal Protection. Compr Physiol. 2021 06 01; 11(3):2075-2095. Liu YY, Brent GA. PMID: 34061976.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansAnimals
    15. Persistent COUP-TFII expression underlies the myopathy and impaired muscle regeneration observed in resistance to thyroid hormone-alpha. Sci Rep. 2021 02 25; 11(1):4601. Aguiari P, Liu YY, Petrosyan A, Cheng SY, Brent GA, Perin L, Milanesi A. PMID: 33633251; PMCID: PMC7907286.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    16. Association of Subclinical Hypothyroidism and Cardiovascular Disease With Mortality. JAMA Netw Open. 2020 02 05; 3(2):e1920745. Inoue K, Ritz B, Brent GA, Ebrahimi R, Rhee CM, Leung AM. PMID: 32031647.
      View in: PubMed   Mentions: 43     Fields:    Translation:Humans
    17. Association of thyroid status prior to transition to end-stage renal disease with early dialysis mortality. Nephrol Dial Transplant. 2019 12 01; 34(12):2095-2104. You AS, Sim JJ, Kovesdy CP, Streja E, Nguyen DV, Brent GA, Kalantar-Zadeh K, Rhee CM. PMID: 30299498; PMCID: PMC6887739.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
    18. Thyroid Hormone Protects Primary Cortical Neurons Exposed to Hypoxia by Reducing DNA Methylation and Apoptosis. Endocrinology. 2019 10 01; 160(10):2243-2256. Li J, Abe K, Milanesi A, Liu YY, Brent GA. PMID: 31095291.
      View in: PubMed   Mentions: 15     Fields:    Translation:AnimalsCells
    19. Older Adults with Cognitive Impairment Have Sex: More Evidence Against the Medical Myth of Sexless Aging. J Am Geriatr Soc. 2018 10; 66(10):1870-1871. Granville L, Brent GA, Pregler J. PMID: 30207596.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    20. Thyroid Status and Death Risk in US Veterans With Chronic Kidney Disease. Mayo Clin Proc. 2018 05; 93(5):573-585. Rhee CM, Kalantar-Zadeh K, Ravel V, Streja E, You AS, Brunelli SM, Nguyen DV, Brent GA, Kovesdy CP. PMID: 29728200; PMCID: PMC6049829.
      View in: PubMed   Mentions: 12     Fields:    Translation:Humans
    21. Thyroid hormone and the brain: Mechanisms of action in development and role in protection and promotion of recovery after brain injury. Pharmacol Ther. 2018 06; 186:176-185. Liu YY, Brent GA. PMID: 29378220; PMCID: PMC5962384.
      View in: PubMed   Mentions: 30     Fields:    Translation:HumansAnimalsCells
    22. COUP-TF1 Modulates Thyroid Hormone Action in an Embryonic Stem-Cell Model of Cortical Pyramidal Neuronal Differentiation. Thyroid. 2018 05; 28(5):667-678. Teng X, Liu YY, Teng W, Brent GA. PMID: 29205104; PMCID: PMC5952340.
      View in: PubMed   Mentions: 6     Fields:    Translation:AnimalsCells
    23. Posttranslational Modification of Thyroid Hormone Nuclear Receptor by Sumoylation. Methods Mol Biol. 2018; 1801:47-59. Liu YY, Brent GA. PMID: 29892816.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansAnimalsCells
    24. Posttranslational Modification of Thyroid Hormone Nuclear Receptor by Phosphorylation. Methods Mol Biol. 2018; 1801:39-46. Liu YY, Brent GA. PMID: 29892815.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansAnimalsCells
    25. Thyroid Hormone Receptor Alpha is Essential to Maintain the Satellite Cell Niche During Skeletal Muscle Injury and Sarcopenia of Aging. Thyroid. 2017 10; 27(10):1316-1322. Milanesi A, Lee JW, Yang A, Liu YY, Sedrakyan S, Cheng SY, Perin L, Brent GA. PMID: 28847239; PMCID: PMC5649408.
      View in: PubMed   Mentions: 18     Fields:    Translation:AnimalsCells
    26. Thyroid Status, Quality of Life, and Mental Health in Patients on Hemodialysis. Clin J Am Soc Nephrol. 2017 Aug 07; 12(8):1274-1283. Rhee CM, Chen Y, You AS, Brunelli SM, Kovesdy CP, Budoff MJ, Brent GA, Kalantar-Zadeh K, Nguyen DV. PMID: 28705886; PMCID: PMC5544520.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansCells
    27. Association of Glycemic Status During Progression of Chronic Kidney Disease With Early Dialysis Mortality in Patients With Diabetes. Diabetes Care. 2017 08; 40(8):1050-1057. Rhee CM, Kovesdy CP, Ravel VA, Streja E, Brunelli SM, Soohoo M, Sumida K, Molnar MZ, Brent GA, Nguyen DV, Kalantar-Zadeh K. PMID: 28592525; PMCID: PMC5521972.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
    28. Thyroid hormone treatment activates protective pathways in both in vivo and in vitro models of neuronal injury. Mol Cell Endocrinol. 2017 09 05; 452:120-130. Li J, Donangelo I, Abe K, Scremin O, Ke S, Li F, Milanesi A, Liu YY, Brent GA. PMID: 28549992.
      View in: PubMed   Mentions: 22     Fields:    Translation:HumansAnimalsCells
    29. Thyroid Status and Mortality in a Prospective Hemodialysis Cohort. J Clin Endocrinol Metab. 2017 05 01; 102(5):1568-1577. Rhee CM, You AS, Nguyen DV, Brunelli SM, Budoff MJ, Streja E, Nakata T, Kovesdy CP, Brent GA, Kalantar-Zadeh K. PMID: 28324018; PMCID: PMC5443328.
      View in: PubMed   Mentions: 20     Fields:    Translation:Humans
    30. Beam Me In: Thyroid Hormone Analog Targets Alternative Transporter in Mouse Model of X-Linked Adrenoleukodystrophy Endocrinology. 2017 04 29; 158(5):1116-1119. Milanesi A, Brent GA. PMID: 28609836; PMCID: PMC5460838.
      View in: PubMed   Mentions: 1     Fields:    
    31. 2017 Guidelines of the American Thyroid Association for the Diagnosis and Management of Thyroid Disease During Pregnancy and the Postpartum. Thyroid. 2017 03; 27(3):315-389. Alexander EK, Pearce EN, Brent GA, Brown RS, Chen H, Dosiou C, Grobman WA, Laurberg P, Lazarus JH, Mandel SJ, Peeters RP, Sullivan S. PMID: 28056690.
      View in: PubMed   Mentions: 699     Fields:    Translation:Humans
    32. Thyroid Functional Disease and Mortality in a National Peritoneal Dialysis Cohort. J Clin Endocrinol Metab. 2016 11; 101(11):4054-4061. Rhee CM, Ravel VA, Streja E, Mehrotra R, Kim S, Wang J, Nguyen DV, Kovesdy CP, Brent GA, Kalantar-Zadeh K. PMID: 27525529; PMCID: PMC5095247.
      View in: PubMed   Mentions: 14     Fields:    Translation:Humans
    33. Exposure to Thyroid-Disrupting Chemicals: A Transatlantic Call for Action. Thyroid. 2016 Apr; 26(4):479-80. Leung AM, Korevaar TI, Peeters RP, Zoeller RT, Köhrle J, Duntas LH, Brent GA, Demeneix BA. PMID: 26906244; PMCID: PMC4827314.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansPHPublic Health
    34. Thyroid Hormone Receptor α Plays an Essential Role in Male Skeletal Muscle Myoblast Proliferation, Differentiation, and Response to Injury. Endocrinology. 2016 Jan; 157(1):4-15. Milanesi A, Lee JW, Kim NH, Liu YY, Yang A, Sedrakyan S, Kahng A, Cervantes V, Tripuraneni N, Cheng SY, Perin L, Brent GA. PMID: 26451739; PMCID: PMC4701883.
      View in: PubMed   Mentions: 26     Fields:    Translation:AnimalsCells
    35. A Patient With a Thyrotropin-Secreting Microadenoma and Resistance to Thyroid Hormone (P453T). J Clin Endocrinol Metab. 2015 Jul; 100(7):2511-4. Teng X, Jin T, Brent GA, Wu A, Teng W, Shan Z. PMID: 25867808; PMCID: PMC5393528.
      View in: PubMed   Mentions: 20     Fields:    Translation:Humans
    36. Association of Adiponectin With Body Composition and Mortality in Hemodialysis Patients. Am J Kidney Dis. 2015 Aug; 66(2):313-21. Rhee CM, Nguyen DV, Moradi H, Brunelli SM, Dukkipati R, Jing J, Nakata T, Kovesdy CP, Brent GA, Kalantar-Zadeh K. PMID: 25824125; PMCID: PMC4516594.
      View in: PubMed   Mentions: 29     Fields:    Translation:Humans
    37. Association of thyroid functional disease with mortality in a national cohort of incident hemodialysis patients. J Clin Endocrinol Metab. 2015 Apr; 100(4):1386-95. Rhee CM, Kim S, Gillen DL, Oztan T, Wang J, Mehrotra R, Kuttykrishnan S, Nguyen DV, Brunelli SM, Kovesdy CP, Brent GA, Kalantar-Zadeh K. PMID: 25632971; PMCID: PMC4399303.
      View in: PubMed   Mentions: 32     Fields:    Translation:Humans
    38. Thyroid hormone receptor sumoylation is required for preadipocyte differentiation and proliferation. J Biol Chem. 2015 Mar 20; 290(12):7402-15. Liu YY, Ayers S, Milanesi A, Teng X, Rabi S, Akiba Y, Brent GA. PMID: 25572392; PMCID: PMC4367250.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansCells
    39. Thyrotoxicosis of Pregnancy. J Clin Transl Endocrinol. 2014 Dec 01; 1(4):140-144. Labadzhyan A, Brent GA, Hershman JM, Leung AM. PMID: 25243108; PMCID: PMC4166486.
      View in: PubMed   Mentions: 8  
    40. A review: Radiographic iodinated contrast media-induced thyroid dysfunction. J Clin Endocrinol Metab. 2015 Feb; 100(2):376-83. Lee SY, Rhee CM, Leung AM, Braverman LE, Brent GA, Pearce EN. PMID: 25375985; PMCID: PMC4318903.
      View in: PubMed   Mentions: 60     Fields:    Translation:Humans
    41. Perchlorate exposure in pregnancy and cognitive outcomes in children: it's not your mother's thyroid. J Clin Endocrinol Metab. 2014 Nov; 99(11):4066-8. Brent GA. PMID: 25372124; PMCID: PMC4223440.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    42. Thyroid hormone regulation of metabolism. Physiol Rev. 2014 Apr; 94(2):355-82. Mullur R, Liu YY, Brent GA. PMID: 24692351; PMCID: PMC4044302.
      View in: PubMed   Mentions: 636     Fields:    Translation:HumansAnimalsCells
    43. Classification and proposed nomenclature for inherited defects of thyroid hormone action, cell transport, and metabolism. Eur Thyroid J. 2014 Mar; 3(1):7-9. Refetoff S, Bassett JH, Beck-Peccoz P, Bernal J, Brent G, Chatterjee K, De Groot LJ, Dumitrescu AM, Jameson JL, Kopp PA, Murata Y, Persani L, Samarut J, Weiss RE, Williams GR, Yen PM. PMID: 24847459; PMCID: PMC4005262.
      View in: PubMed   Mentions: 11  
    44. Classification and proposed nomenclature for inherited defects of thyroid hormone action, cell transport, and metabolism. Thyroid. 2014 Mar; 24(3):407-9. Refetoff S, Bassett JH, Beck-Peccoz P, Bernal J, Brent G, Chatterjee K, De Groot LJ, Dumitrescu AM, Jameson JL, Kopp PA, Murata Y, Persani L, Samarut J, Weiss RE, Williams GR, Yen PM. PMID: 24588711; PMCID: PMC3950730.
      View in: PubMed   Mentions: 15     Fields:    Translation:Humans
    45. Classification and proposed nomenclature for inherited defects of thyroid hormone action, cell transport, and metabolism. J Clin Endocrinol Metab. 2014 Mar; 99(3):768-70. Refetoff S, Bassett JH, Beck-Peccoz P, Bernal J, Brent G, Chatterjee K, De Groot LJ, Dumitrescu AM, Jameson JL, Kopp PA, Murata Y, Persani L, Samarut J, Weiss RE, Williams GR, Yen PM. PMID: 24823702; PMCID: PMC3942236.
      View in: PubMed   Mentions: 20     Fields:    Translation:Humans
    46. Updates on the management of diabetes in dialysis patients. Semin Dial. 2014 Mar; 27(2):135-45. Rhee CM, Leung AM, Kovesdy CP, Lynch KE, Brent GA, Kalantar-Zadeh K. PMID: 24588802; PMCID: PMC3960718.
      View in: PubMed   Mentions: 42     Fields:    Translation:Humans
    47. Thyroid functional disease: an under-recognized cardiovascular risk factor in kidney disease patients. Nephrol Dial Transplant. 2015 May; 30(5):724-37. Rhee CM, Brent GA, Kovesdy CP, Soldin OP, Nguyen D, Budoff MJ, Brunelli SM, Kalantar-Zadeh K. PMID: 24574542; PMCID: PMC4425477.
      View in: PubMed   Mentions: 45     Fields:    Translation:HumansAnimals
    48. Commentary on: "American Thyroid Association Guide to investigating thyroid hormone economy and action in rodent and cell models," Bianco et al. Thyroid. 2014 Jan; 24(1):1-2. Brent GA. PMID: 24303889; PMCID: PMC3887401.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimals
    49. Children of mothers with iodine deficiency during pregnancy are more likely to have lower verbal IQ and reading scores at 8-9 years of age. Evid Based Nurs. 2014 Jul; 17(3):86. Leung AM, Brent GA. PMID: 24336752; PMCID: PMC4055540.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    50. Cancer: Novel target to enhance radioiodine uptake in thyroid cancer. Nat Rev Endocrinol. 2013 Sep; 9(9):508-9. Brent GA, Kogai T. PMID: 23817292.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimalsCells
    51. Mechanisms of thyroid hormone action. J Clin Invest. 2012 Sep; 122(9):3035-43. Brent GA. PMID: 22945636; PMCID: PMC3433956.
      View in: PubMed   Mentions: 356     Fields:    Translation:HumansAnimalsCells
    52. Thyroid hormone receptor isoform-specific modification by small ubiquitin-like modifier (SUMO) modulates thyroid hormone-dependent gene regulation. J Biol Chem. 2012 Oct 19; 287(43):36499-508. Liu YY, Kogai T, Schultz JJ, Mody K, Brent GA. PMID: 22930759; PMCID: PMC3476315.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansAnimalsCells
    53. The sodium iodide symporter (NIS): regulation and approaches to targeting for cancer therapeutics. Pharmacol Ther. 2012 Sep; 135(3):355-70. Kogai T, Brent GA. PMID: 22750642; PMCID: PMC3408573.
      View in: PubMed   Mentions: 78     Fields:    Translation:HumansAnimalsCells
    54. The debate over thyroid-function screening in pregnancy. N Engl J Med. 2012 Feb 09; 366(6):562-3. Brent GA. PMID: 22316450.
      View in: PubMed   Mentions: 14     Fields:    Translation:Humans
    55. Regulation of sodium iodide symporter gene expression by Rac1/p38β mitogen-activated protein kinase signaling pathway in MCF-7 breast cancer cells. J Biol Chem. 2012 Jan 27; 287(5):3292-300. Kogai T, Liu YY, Mody K, Shamsian DV, Brent GA. PMID: 22157753; PMCID: PMC3270984.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansAnimalsCells
    56. Management of hypothyroidism in pregnancy. Curr Opin Endocrinol Diabetes Obes. 2011 Oct; 18(5):304-9. Milanesi A, Brent GA. PMID: 21841481.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    57. Publication of industry-sponsored medical research: guidelines from the Consortium of Laboratory Medicine Journal Editors. Thyroid. 2011 Jul; 21(7):693. Soldin OP, Brent GA, Kloos RT. PMID: 21707435.
      View in: PubMed   Mentions:    Fields:    
    58. Thyroid hormone and COUP-TF1 regulate kallikrein-binding protein (KBP) gene expression. Endocrinology. 2011 Mar; 152(3):1143-53. Liu YY, Nakatani T, Kogai T, Mody K, Brent GA. PMID: 21266512; PMCID: PMC3040047.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimalsCells
    59. The impact of perchlorate exposure in early pregnancy: is it safe to drink the water? J Clin Endocrinol Metab. 2010 Jul; 95(7):3154-7. Brent GA. PMID: 20610607; PMCID: PMC2928898.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansPHPublic Health
    60. Environmental exposures and autoimmune thyroid disease. Thyroid. 2010 Jul; 20(7):755-61. Brent GA. PMID: 20578899; PMCID: PMC2935336.
      View in: PubMed   Mentions: 46     Fields:    Translation:HumansAnimalsPHPublic Health
    61. Retinoic acid induces expression of the thyroid hormone transporter, monocarboxylate transporter 8 (Mct8). J Biol Chem. 2010 Aug 27; 285(35):27279-27288. Kogai T, Liu YY, Richter LL, Mody K, Kagechika H, Brent GA. PMID: 20573951; PMCID: PMC2930727.
      View in: PubMed   Mentions: 15     Fields:    Translation:AnimalsCells
    62. Thyroid hormone crosstalk with nuclear receptor signaling in metabolic regulation. Trends Endocrinol Metab. 2010 Mar; 21(3):166-73. Liu YY, Brent GA. PMID: 20015660; PMCID: PMC2831161.
      View in: PubMed   Mentions: 73     Fields:    Translation:HumansAnimalsCells
    63. Expression of uncoupling protein 1 in mouse brown adipose tissue is thyroid hormone receptor-beta isoform specific and required for adaptive thermogenesis. Endocrinology. 2010 Jan; 151(1):432-40. Ribeiro MO, Bianco SD, Kaneshige M, Schultz JJ, Cheng SY, Bianco AC, Brent GA. PMID: 19906816; PMCID: PMC2817565.
      View in: PubMed   Mentions: 52     Fields:    Translation:AnimalsCells
    64. Activation of the PI3 kinase pathway by retinoic acid mediates sodium/iodide symporter induction and iodide transport in MCF-7 breast cancer cells. Cancer Res. 2009 Apr 15; 69(8):3443-50. Ohashi E, Kogai T, Kagechika H, Brent GA. PMID: 19351850; PMCID: PMC2852426.
      View in: PubMed   Mentions: 21     Fields:    Translation:HumansAnimalsCells
    65. Phosphoinositide-3-kinase inhibition induces sodium/iodide symporter expression in rat thyroid cells and human papillary thyroid cancer cells. J Endocrinol. 2008 Nov; 199(2):243-52. Kogai T, Sajid-Crockett S, Newmarch LS, Liu YY, Brent GA. PMID: 18762555.
      View in: PubMed   Mentions: 51     Fields:    Translation:HumansAnimalsCells
    66. Clinical practice. Graves' disease. N Engl J Med. 2008 Jun 12; 358(24):2594-605. Brent GA. PMID: 18550875.
      View in: PubMed   Mentions: 170     Fields:    Translation:Humans
    67. Stealth sequences in reporter gene vectors confound studies of T3-regulated negative gene expression. Thyroid. 2008 Jun; 18(6):593-5. Liu YY, Brent GA. PMID: 18578606.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimalsCells
    68. Retinoic acid stimulation of the sodium/iodide symporter in MCF-7 breast cancer cells is mediated by the insulin growth factor-I/phosphatidylinositol 3-kinase and p38 mitogen-activated protein kinase signaling pathways. J Clin Endocrinol Metab. 2008 May; 93(5):1884-92. Kogai T, Ohashi E, Jacobs MS, Sajid-Crockett S, Fisher ML, Kanamoto Y, Brent GA. PMID: 18319322; PMCID: PMC2386284.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansCells
    69. Thyroid health and the environment. Thyroid. 2007 Sep; 17(9):807-9. Brent GA, Braverman LE, Zoeller RT. PMID: 17956154.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansPHPublic Health
    70. Diagnosing thyroid dysfunction in pregnant women: Is case finding enough? J Clin Endocrinol Metab. 2007 Jan; 92(1):39-41. Brent GA. PMID: 17209222.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    71. Thyroid hormone regulates endogenous amyloid-beta precursor protein gene expression and processing in both in vitro and in vivo models. Thyroid. 2006 Dec; 16(12):1207-13. O'Barr SA, Oh JS, Ma C, Brent GA, Schultz JJ. PMID: 17199430.
      View in: PubMed   Mentions: 23     Fields:    Translation:HumansAnimalsCells
    72. A mutant thyroid hormone receptor alpha antagonizes peroxisome proliferator-activated receptor alpha signaling in vivo and impairs fatty acid oxidation. Endocrinology. 2007 Mar; 148(3):1206-17. Liu YY, Heymann RS, Moatamed F, Schultz JJ, Sobel D, Brent GA. PMID: 17122078.
      View in: PubMed   Mentions: 33     Fields:    Translation:AnimalsCells
    73. Anaplastic thyroid carcinoma with thyrotoxicosis and hypoparathyroidism. Endocr Pract. 2005 Jul-Aug; 11(4):281-4. Heymann RS, Brent GA, Hershman JM. PMID: 16006301.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    74. Differential regulation of sodium/iodide symporter gene expression by nuclear receptor ligands in MCF-7 breast cancer cells. Endocrinology. 2005 Jul; 146(7):3059-69. Kogai T, Kanamoto Y, Li AI, Che LH, Ohashi E, Taki K, Chandraratna RA, Saito T, Brent GA. PMID: 15817668.
      View in: PubMed   Mentions: 21     Fields:    Translation:HumansCells
    75. Rapid progression from subclinical to symptomatic overt hypothyroidism. Endocr Pract. 2005 Mar-Apr; 11(2):115-9. Heymann R, Brent GA. PMID: 15901527.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    76. Resistance to thyroid hormone in Hashimoto's thyroiditis. N Engl J Med. 2005 Feb 03; 352(5):517-8. Fukata S, Brent GA, Sugawara M. PMID: 15689599.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    77. Thyroid function inside and outside of pregnancy: what do we know and what don't we know? Thyroid. 2005 Jan; 15(1):54-9. Smallridge RC, Glinoer D, Hollowell JG, Brent G. PMID: 15687824.
      View in: PubMed   Mentions: 15     Fields:    Translation:Humans
    78. Introduction. The impact of maternal thyroid diseases on the developing fetus: implications for diagnosis, treatment, and screening. Summary of proceedings, workshop organization, program, and participants. Thyroid. 2005 Jan; 15(1):36-40. Brent G, Boyle CA. PMID: 15687821.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    79. Regulation of regional expression in rat brain PC2 by thyroid hormone/characterization of novel negative thyroid hormone response elements in the PC2 promoter. Am J Physiol Endocrinol Metab. 2005 Jan; 288(1):E236-45. Shen X, Li QL, Brent GA, Friedman TC. PMID: 15585599.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    80. Thyroid hormone-dependent gene expression in differentiated embryonic stem cells and embryonal carcinoma cells: identification of novel thyroid hormone target genes by deoxyribonucleic acid microarray analysis. Endocrinology. 2005 Feb; 146(2):776-83. Liu YY, Brent GA. PMID: 15550503.
      View in: PubMed   Mentions: 8     Fields:    Translation:AnimalsCells
    81. Systemic retinoic acid treatment induces sodium/iodide symporter expression and radioiodide uptake in mouse breast cancer models. Cancer Res. 2004 Jan 01; 64(1):415-22. Kogai T, Kanamoto Y, Che LH, Taki K, Moatamed F, Schultz JJ, Brent GA. PMID: 14729653.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansAnimalsCells
    82. Enhanced expression of nicotinamide N-methyltransferase in human papillary thyroid carcinoma cells. J Clin Endocrinol Metab. 2003 Oct; 88(10):4990-6. Xu J, Moatamed F, Caldwell JS, Walker JR, Kraiem Z, Taki K, Brent GA, Hershman JM. PMID: 14557485.
      View in: PubMed   Mentions: 34     Fields:    Translation:HumansCells
    83. Spared bone mass in rats treated with thyroid hormone receptor TR beta-selective compound GC-1. Am J Physiol Endocrinol Metab. 2003 Nov; 285(5):E1135-41. Freitas FR, Moriscot AS, Jorgetti V, Soares AG, Passarelli M, Scanlan TS, Brent GA, Bianco AC, Gouveia CH. PMID: 12965872.
      View in: PubMed   Mentions: 22     Fields:    Translation:Animals
    84. Follow-up of newborns with elevated screening T4 concentrations. J Pediatr. 2003 Sep; 143(3):296-301. Lafranchi SH, Snyder DB, Sesser DE, Skeels MR, Singh N, Brent GA, Nelson JC. PMID: 14517508.
      View in: PubMed   Mentions: 44     Fields:    Translation:HumansPHPublic Health
    85. Nonradioactive iodide effectively induces apoptosis in genetically modified lung cancer cells. Cancer Res. 2003 Aug 15; 63(16):5065-72. Zhang L, Sharma S, Zhu LX, Kogai T, Hershman JM, Brent GA, Dubinett SM, Huang M. PMID: 12941836.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansAnimalsCells
    86. A thyroid hormone receptor alpha gene mutation (P398H) is associated with visceral adiposity and impaired catecholamine-stimulated lipolysis in mice. J Biol Chem. 2003 Oct 03; 278(40):38913-20. Liu YY, Schultz JJ, Brent GA. PMID: 12869545.
      View in: PubMed   Mentions: 49     Fields:    Translation:AnimalsCells
    87. The modified firefly luciferase reporter gene (luc+) but not Renilla luciferase is induced by all-trans retinoic acid in MCF-7 breast cancer cells. Breast Cancer Res Treat. 2003 Mar; 78(1):119-26. Kogai T, Kanamoto Y, Brent GA. PMID: 12611464.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansAnimalsCells
    88. Thyroid hormone gene targets in ROS 17/2.8 osteoblast-like cells identified by differential display analysis. Thyroid. 2002 Aug; 12(8):663-71. Gouveia CH, Schultz JJ, Jackson DJ, Williams GR, Brent GA. PMID: 12225634.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    89. A GC box in the human sodium iodide symporter gene promoter is essential for full activity. Thyroid. 2002 Feb; 12(2):107-14. Xu J, Kogai T, Brent GA, Hershman JM. PMID: 11916279.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimalsCells
    90. The Kaposi sarcoma-associated herpesvirus (KSHV) induces cellular interleukin 6 expression: role of the KSHV latency-associated nuclear antigen and the AP1 response element. Blood. 2002 Jan 15; 99(2):649-54. An J, Lichtenstein AK, Brent G, Rettig MB. PMID: 11781250.
      View in: PubMed   Mentions: 49     Fields:    Translation:HumansCells
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