Gregory A Brent

Title(s)Department Vice Chair, Medicine Dept.
SchoolMedicine
Emailgbrent@mednet.ucla.edu
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    Other Positions
    Title(s)Professor, Medicine

    Title(s)Professor, Physiology


    Collapse Research 
    Collapse Research Activities and Funding
    Thyroid Hormone Receptor Isoform-Specific Actions
    NIH R01DK098576May 1, 2014 - Feb 28, 2019
    Role: Principal Investigator
    Thyroid Hormone and Neuronal Protection
    NIH I01BX001966Jan 1, 2014 - Mar 31, 2023
    Role: Principal Investigator
    Thyroid Hormone Receptor Isoform-Specific Actions
    NIH R01DK067233Mar 1, 2004 - Feb 28, 2010
    Role: Principal Investigator
    Regulation of the Sodium/Iodide Symporter in Breast
    NIH R01CA089364Jan 12, 2001 - Apr 30, 2013
    Role: Principal Investigator
    ANIMAL AND CELLULAR MODELS OF THYROID HORMONE RESISTANCE
    NIH R01DK043714Feb 1, 1992 - Apr 30, 2001
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    1. Weighing in on Thyroid Signaling in the Hypothalamus: Mechanisms and Interface with Metabolic Regulators. Thyroid. 2024 Jan 25. Milanesi A, Brent GA. PMID: 38269429.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    2. A New Twist on a Classic: Enhancing Radioiodine Uptake in Advanced Thyroid Cancer. Clin Cancer Res. 2024 Jan 10. Lechner MG, Brent GA. PMID: 38197869.
      View in: PubMed   Mentions:    Fields:    
    3. Impact of Thyroid Status on Incident Kidney Dysfunction and Chronic Kidney Disease Progression in a Nationally Representative Cohort. Mayo Clin Proc. 2024 Jan; 99(1):39-56. You AS, Kalantar-Zadeh K, Brent GA, Narasaki Y, Daza A, Sim JJ, Kovesdy CP, Nguyen DV, Rhee CM. PMID: 38176833; PMCID: PMC10795379.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    4. Pregnancy - Does Promotion of Growth Extend to Thyroid Cancer? J Clin Endocrinol Metab. 2023 Dec 02. Leung AM, Brent GA. PMID: 38041866.
      View in: PubMed   Mentions:    Fields:    
    5. Development and Validation of a Prediction Model for Incident Hypothyroidism in a National Chronic Kidney Disease Cohort. J Clin Endocrinol Metab. 2023 10 18; 108(11):e1374-e1383. Rhee CM, You AS, Narasaki Y, Brent GA, Sim JJ, Kovesdy CP, Kalantar-Zadeh K, Nguyen DV. PMID: 37186674.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    6. A Historical Reflection on Scientific Advances in Understanding Thyroid Hormone Action. Thyroid. 2023 Oct; 33(10):1140-1149. Brent GA. PMID: 37594753.
      View in: PubMed   Mentions:    Fields:    
    7. Approach to the Patient With a Suppressed TSH. J Clin Endocrinol Metab. 2023 01 17; 108(2):472-482. Praw SS, Brent GA. PMID: 36329632.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    8. Thyroid Hormone-mediated Histone Modification Protects Cortical Neurons From the Toxic Effects of Hypoxic Injury. J Endocr Soc. 2022 Oct 11; 6(11):bvac139. Abe K, Li J, Liu YY, Brent GA. PMID: 36817622; PMCID: PMC9562813.
      View in: PubMed   Mentions: 2  
    9. Serum Thyrotropin Elevation and Coronary Artery Calcification in Hemodialysis Patients. Cardiorenal Med. 2022; 12(3):106-116. Rhee CM, Budoff M, Brent G, You AS, Stenvinkel P, Novoa A, Flores F, Hamal S, Dailing C, Kinninger A, Nakata T, Kovesdy CP, Nguyen DV, Kalantar-Zadeh K. PMID: 35551382; PMCID: PMC9452456.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    10. Serum Thyroglobulin Measurement Following Surgery Without Radioactive Iodine for Differentiated Thyroid Cancer: A Systematic Review. Thyroid. 2022 06; 32(6):613-639. Chou R, Dana T, Brent GA, Goldner W, Haymart M, Leung AM, Ringel MD, Sosa JA. PMID: 35412871.
      View in: PubMed   Mentions: 12     Fields:    Translation:Humans
    11. Thyroid hormone receptor alpha sumoylation modulates white adipose tissue stores. Sci Rep. 2021 12 16; 11(1):24105. Liu YY, Jiang J, Ke S, Milanesi A, Abe K, Gastelum G, Li J, Brent GA. PMID: 34916557; PMCID: PMC8677787.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    12. Thyroid hormone receptor β sumoylation is required for thyrotropin regulation and thyroid hormone production. JCI Insight. 2021 08 23; 6(16). Ke S, Liu YY, Karthikraj R, Kannan K, Jiang J, Abe K, Milanesi A, Brent GA. PMID: 34237030; PMCID: PMC8410017.
      View in: PubMed   Mentions: 4     Fields:    Translation:AnimalsCells
    13. Elevated serum thyrotropin levels and endothelial dysfunction in a prospective hemodialysis cohort. Hemodial Int. 2022 01; 26(1):57-65. You AS, Budoff M, Zeb I, Ahmadi N, Novoa A, Flores F, Hamal S, Kinninger A, Dailing C, Nakata T, Kovesdy CP, Nguyen DV, Brent GA, Kalantar-Zadeh K, Rhee CM. PMID: 34231302; PMCID: PMC10753993.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    14. The Role of Thyroid Hormone in Neuronal Protection. Compr Physiol. 2021 06 01; 11(3):2075-2095. Liu YY, Brent GA. PMID: 34061976.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimals
    15. Persistent COUP-TFII expression underlies the myopathy and impaired muscle regeneration observed in resistance to thyroid hormone-alpha. Sci Rep. 2021 02 25; 11(1):4601. Aguiari P, Liu YY, Petrosyan A, Cheng SY, Brent GA, Perin L, Milanesi A. PMID: 33633251; PMCID: PMC7907286.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    16. Association of Subclinical Hypothyroidism and Cardiovascular Disease With Mortality. JAMA Netw Open. 2020 02 05; 3(2):e1920745. Inoue K, Ritz B, Brent GA, Ebrahimi R, Rhee CM, Leung AM. PMID: 32031647.
      View in: PubMed   Mentions: 41     Fields:    Translation:Humans
    17. Association of thyroid status prior to transition to end-stage renal disease with early dialysis mortality. Nephrol Dial Transplant. 2019 12 01; 34(12):2095-2104. You AS, Sim JJ, Kovesdy CP, Streja E, Nguyen DV, Brent GA, Kalantar-Zadeh K, Rhee CM. PMID: 30299498; PMCID: PMC6887739.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
    18. Thyroid Hormone Protects Primary Cortical Neurons Exposed to Hypoxia by Reducing DNA Methylation and Apoptosis. Endocrinology. 2019 10 01; 160(10):2243-2256. Li J, Abe K, Milanesi A, Liu YY, Brent GA. PMID: 31095291.
      View in: PubMed   Mentions: 14     Fields:    Translation:AnimalsCells
    19. Older Adults with Cognitive Impairment Have Sex: More Evidence Against the Medical Myth of Sexless Aging. J Am Geriatr Soc. 2018 10; 66(10):1870-1871. Granville L, Brent GA, Pregler J. PMID: 30207596.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    20. Thyroid Status and Death Risk in US Veterans With Chronic Kidney Disease. Mayo Clin Proc. 2018 05; 93(5):573-585. Rhee CM, Kalantar-Zadeh K, Ravel V, Streja E, You AS, Brunelli SM, Nguyen DV, Brent GA, Kovesdy CP. PMID: 29728200; PMCID: PMC6049829.
      View in: PubMed   Mentions: 12     Fields:    Translation:Humans
    21. Thyroid hormone and the brain: Mechanisms of action in development and role in protection and promotion of recovery after brain injury. Pharmacol Ther. 2018 06; 186:176-185. Liu YY, Brent GA. PMID: 29378220; PMCID: PMC5962384.
      View in: PubMed   Mentions: 31     Fields:    Translation:HumansAnimalsCells
    22. COUP-TF1 Modulates Thyroid Hormone Action in an Embryonic Stem-Cell Model of Cortical Pyramidal Neuronal Differentiation. Thyroid. 2018 05; 28(5):667-678. Teng X, Liu YY, Teng W, Brent GA. PMID: 29205104; PMCID: PMC5952340.
      View in: PubMed   Mentions: 5     Fields:    Translation:AnimalsCells
    23. Posttranslational Modification of Thyroid Hormone Nuclear Receptor by Phosphorylation. Methods Mol Biol. 2018; 1801:39-46. Liu YY, Brent GA. PMID: 29892815.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansAnimalsCells
    24. Posttranslational Modification of Thyroid Hormone Nuclear Receptor by Sumoylation. Methods Mol Biol. 2018; 1801:47-59. Liu YY, Brent GA. PMID: 29892816.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansAnimalsCells
    25. Thyroid Hormone Receptor Alpha is Essential to Maintain the Satellite Cell Niche During Skeletal Muscle Injury and Sarcopenia of Aging. Thyroid. 2017 10; 27(10):1316-1322. Milanesi A, Lee JW, Yang A, Liu YY, Sedrakyan S, Cheng SY, Perin L, Brent GA. PMID: 28847239; PMCID: PMC5649408.
      View in: PubMed   Mentions: 18     Fields:    Translation:AnimalsCells
    26. Thyroid Status, Quality of Life, and Mental Health in Patients on Hemodialysis. Clin J Am Soc Nephrol. 2017 Aug 07; 12(8):1274-1283. Rhee CM, Chen Y, You AS, Brunelli SM, Kovesdy CP, Budoff MJ, Brent GA, Kalantar-Zadeh K, Nguyen DV. PMID: 28705886; PMCID: PMC5544520.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansCells
    27. Association of Glycemic Status During Progression of Chronic Kidney Disease With Early Dialysis Mortality in Patients With Diabetes. Diabetes Care. 2017 08; 40(8):1050-1057. Rhee CM, Kovesdy CP, Ravel VA, Streja E, Brunelli SM, Soohoo M, Sumida K, Molnar MZ, Brent GA, Nguyen DV, Kalantar-Zadeh K. PMID: 28592525; PMCID: PMC5521972.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
    28. Thyroid hormone treatment activates protective pathways in both in vivo and in vitro models of neuronal injury. Mol Cell Endocrinol. 2017 09 05; 452:120-130. Li J, Donangelo I, Abe K, Scremin O, Ke S, Li F, Milanesi A, Liu YY, Brent GA. PMID: 28549992.
      View in: PubMed   Mentions: 22     Fields:    Translation:HumansAnimalsCells
    29. Thyroid Status and Mortality in a Prospective Hemodialysis Cohort. J Clin Endocrinol Metab. 2017 05 01; 102(5):1568-1577. Rhee CM, You AS, Nguyen DV, Brunelli SM, Budoff MJ, Streja E, Nakata T, Kovesdy CP, Brent GA, Kalantar-Zadeh K. PMID: 28324018; PMCID: PMC5443328.
      View in: PubMed   Mentions: 19     Fields:    Translation:Humans
    30. Beam Me In: Thyroid Hormone Analog Targets Alternative Transporter in Mouse Model of X-Linked Adrenoleukodystrophy Endocrinology. 2017 04 29; 158(5):1116-1119. Milanesi A, Brent GA. PMID: 28609836; PMCID: PMC5460838.
      View in: PubMed   Mentions: 1     Fields:    
    31. 2017 Guidelines of the American Thyroid Association for the Diagnosis and Management of Thyroid Disease During Pregnancy and the Postpartum. Thyroid. 2017 03; 27(3):315-389. Alexander EK, Pearce EN, Brent GA, Brown RS, Chen H, Dosiou C, Grobman WA, Laurberg P, Lazarus JH, Mandel SJ, Peeters RP, Sullivan S. PMID: 28056690.
      View in: PubMed   Mentions: 691     Fields:    Translation:Humans
    32. Thyroid Functional Disease and Mortality in a National Peritoneal Dialysis Cohort. J Clin Endocrinol Metab. 2016 11; 101(11):4054-4061. Rhee CM, Ravel VA, Streja E, Mehrotra R, Kim S, Wang J, Nguyen DV, Kovesdy CP, Brent GA, Kalantar-Zadeh K. PMID: 27525529; PMCID: PMC5095247.
      View in: PubMed   Mentions: 14     Fields:    Translation:Humans
    33. Exposure to Thyroid-Disrupting Chemicals: A Transatlantic Call for Action. Thyroid. 2016 Apr; 26(4):479-80. Leung AM, Korevaar TI, Peeters RP, Zoeller RT, Köhrle J, Duntas LH, Brent GA, Demeneix BA. PMID: 26906244; PMCID: PMC4827314.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansPHPublic Health
    34. Thyroid Hormone Receptor α Plays an Essential Role in Male Skeletal Muscle Myoblast Proliferation, Differentiation, and Response to Injury. Endocrinology. 2016 Jan; 157(1):4-15. Milanesi A, Lee JW, Kim NH, Liu YY, Yang A, Sedrakyan S, Kahng A, Cervantes V, Tripuraneni N, Cheng SY, Perin L, Brent GA. PMID: 26451739; PMCID: PMC4701883.
      View in: PubMed   Mentions: 26     Fields:    Translation:AnimalsCells
    35. A Patient With a Thyrotropin-Secreting Microadenoma and Resistance to Thyroid Hormone (P453T). J Clin Endocrinol Metab. 2015 Jul; 100(7):2511-4. Teng X, Jin T, Brent GA, Wu A, Teng W, Shan Z. PMID: 25867808; PMCID: PMC5393528.
      View in: PubMed   Mentions: 18     Fields:    Translation:Humans
    36. Association of Adiponectin With Body Composition and Mortality in Hemodialysis Patients. Am J Kidney Dis. 2015 Aug; 66(2):313-21. Rhee CM, Nguyen DV, Moradi H, Brunelli SM, Dukkipati R, Jing J, Nakata T, Kovesdy CP, Brent GA, Kalantar-Zadeh K. PMID: 25824125; PMCID: PMC4516594.
      View in: PubMed   Mentions: 28     Fields:    Translation:Humans
    37. Association of thyroid functional disease with mortality in a national cohort of incident hemodialysis patients. J Clin Endocrinol Metab. 2015 Apr; 100(4):1386-95. Rhee CM, Kim S, Gillen DL, Oztan T, Wang J, Mehrotra R, Kuttykrishnan S, Nguyen DV, Brunelli SM, Kovesdy CP, Brent GA, Kalantar-Zadeh K. PMID: 25632971; PMCID: PMC4399303.
      View in: PubMed   Mentions: 32     Fields:    Translation:Humans
    38. Thyroid hormone receptor sumoylation is required for preadipocyte differentiation and proliferation. J Biol Chem. 2015 Mar 20; 290(12):7402-15. Liu YY, Ayers S, Milanesi A, Teng X, Rabi S, Akiba Y, Brent GA. PMID: 25572392; PMCID: PMC4367250.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansCells
    39. Thyrotoxicosis of Pregnancy. J Clin Transl Endocrinol. 2014 Dec 01; 1(4):140-144. Labadzhyan A, Brent GA, Hershman JM, Leung AM. PMID: 25243108; PMCID: PMC4166486.
      View in: PubMed   Mentions: 9  
    40. A review: Radiographic iodinated contrast media-induced thyroid dysfunction. J Clin Endocrinol Metab. 2015 Feb; 100(2):376-83. Lee SY, Rhee CM, Leung AM, Braverman LE, Brent GA, Pearce EN. PMID: 25375985; PMCID: PMC4318903.
      View in: PubMed   Mentions: 57     Fields:    Translation:Humans
    41. Perchlorate exposure in pregnancy and cognitive outcomes in children: it's not your mother's thyroid. J Clin Endocrinol Metab. 2014 Nov; 99(11):4066-8. Brent GA. PMID: 25372124; PMCID: PMC4223440.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    42. Thyroid hormone regulation of metabolism. Physiol Rev. 2014 Apr; 94(2):355-82. Mullur R, Liu YY, Brent GA. PMID: 24692351; PMCID: PMC4044302.
      View in: PubMed   Mentions: 627     Fields:    Translation:HumansAnimalsCells
    43. Classification and proposed nomenclature for inherited defects of thyroid hormone action, cell transport, and metabolism. Eur Thyroid J. 2014 Mar; 3(1):7-9. Refetoff S, Bassett JH, Beck-Peccoz P, Bernal J, Brent G, Chatterjee K, De Groot LJ, Dumitrescu AM, Jameson JL, Kopp PA, Murata Y, Persani L, Samarut J, Weiss RE, Williams GR, Yen PM. PMID: 24847459; PMCID: PMC4005262.
      View in: PubMed   Mentions: 11  
    44. Classification and proposed nomenclature for inherited defects of thyroid hormone action, cell transport, and metabolism. Thyroid. 2014 Mar; 24(3):407-9. Refetoff S, Bassett JH, Beck-Peccoz P, Bernal J, Brent G, Chatterjee K, De Groot LJ, Dumitrescu AM, Jameson JL, Kopp PA, Murata Y, Persani L, Samarut J, Weiss RE, Williams GR, Yen PM. PMID: 24588711; PMCID: PMC3950730.
      View in: PubMed   Mentions: 15     Fields:    Translation:Humans
    45. Updates on the management of diabetes in dialysis patients. Semin Dial. 2014 Mar; 27(2):135-45. Rhee CM, Leung AM, Kovesdy CP, Lynch KE, Brent GA, Kalantar-Zadeh K. PMID: 24588802; PMCID: PMC3960718.
      View in: PubMed   Mentions: 45     Fields:    Translation:Humans
    46. Classification and proposed nomenclature for inherited defects of thyroid hormone action, cell transport, and metabolism. J Clin Endocrinol Metab. 2014 Mar; 99(3):768-70. Refetoff S, Bassett JH, Beck-Peccoz P, Bernal J, Brent G, Chatterjee K, De Groot LJ, Dumitrescu AM, Jameson JL, Kopp PA, Murata Y, Persani L, Samarut J, Weiss RE, Williams GR, Yen PM. PMID: 24823702; PMCID: PMC3942236.
      View in: PubMed   Mentions: 21     Fields:    Translation:Humans
    47. Thyroid functional disease: an under-recognized cardiovascular risk factor in kidney disease patients. Nephrol Dial Transplant. 2015 May; 30(5):724-37. Rhee CM, Brent GA, Kovesdy CP, Soldin OP, Nguyen D, Budoff MJ, Brunelli SM, Kalantar-Zadeh K. PMID: 24574542; PMCID: PMC4425477.
      View in: PubMed   Mentions: 44     Fields:    Translation:HumansAnimals
    48. Commentary on: "American Thyroid Association Guide to investigating thyroid hormone economy and action in rodent and cell models," Bianco et al. Thyroid. 2014 Jan; 24(1):1-2. Brent GA. PMID: 24303889; PMCID: PMC3887401.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimals
    49. Children of mothers with iodine deficiency during pregnancy are more likely to have lower verbal IQ and reading scores at 8-9 years of age. Evid Based Nurs. 2014 Jul; 17(3):86. Leung AM, Brent GA. PMID: 24336752; PMCID: PMC4055540.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    50. Cancer: Novel target to enhance radioiodine uptake in thyroid cancer. Nat Rev Endocrinol. 2013 Sep; 9(9):508-9. Brent GA, Kogai T. PMID: 23817292.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimalsCells
    51. Mechanisms of thyroid hormone action. J Clin Invest. 2012 Sep; 122(9):3035-43. Brent GA. PMID: 22945636; PMCID: PMC3433956.
      View in: PubMed   Mentions: 351     Fields:    Translation:HumansAnimalsCells
    52. Thyroid hormone receptor isoform-specific modification by small ubiquitin-like modifier (SUMO) modulates thyroid hormone-dependent gene regulation. J Biol Chem. 2012 Oct 19; 287(43):36499-508. Liu YY, Kogai T, Schultz JJ, Mody K, Brent GA. PMID: 22930759; PMCID: PMC3476315.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansAnimalsCells
    53. The sodium iodide symporter (NIS): regulation and approaches to targeting for cancer therapeutics. Pharmacol Ther. 2012 Sep; 135(3):355-70. Kogai T, Brent GA. PMID: 22750642; PMCID: PMC3408573.
      View in: PubMed   Mentions: 79     Fields:    Translation:HumansAnimalsCells
    54. The debate over thyroid-function screening in pregnancy. N Engl J Med. 2012 Feb 09; 366(6):562-3. Brent GA. PMID: 22316450.
      View in: PubMed   Mentions: 14     Fields:    Translation:Humans
    55. Regulation of sodium iodide symporter gene expression by Rac1/p38β mitogen-activated protein kinase signaling pathway in MCF-7 breast cancer cells. J Biol Chem. 2012 Jan 27; 287(5):3292-300. Kogai T, Liu YY, Mody K, Shamsian DV, Brent GA. PMID: 22157753; PMCID: PMC3270984.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansAnimalsCells
    56. Management of hypothyroidism in pregnancy. Curr Opin Endocrinol Diabetes Obes. 2011 Oct; 18(5):304-9. Milanesi A, Brent GA. PMID: 21841481.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    57. Publication of industry-sponsored medical research: guidelines from the Consortium of Laboratory Medicine Journal Editors. Thyroid. 2011 Jul; 21(7):693. Soldin OP, Brent GA, Kloos RT. PMID: 21707435.
      View in: PubMed   Mentions:    Fields:    
    58. Thyroid hormone and COUP-TF1 regulate kallikrein-binding protein (KBP) gene expression. Endocrinology. 2011 Mar; 152(3):1143-53. Liu YY, Nakatani T, Kogai T, Mody K, Brent GA. PMID: 21266512; PMCID: PMC3040047.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimalsCells
    59. Environmental exposures and autoimmune thyroid disease. Thyroid. 2010 Jul; 20(7):755-61. Brent GA. PMID: 20578899; PMCID: PMC2935336.
      View in: PubMed   Mentions: 46     Fields:    Translation:HumansAnimalsPHPublic Health
    60. The impact of perchlorate exposure in early pregnancy: is it safe to drink the water? J Clin Endocrinol Metab. 2010 Jul; 95(7):3154-7. Brent GA. PMID: 20610607; PMCID: PMC2928898.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansPHPublic Health
    61. Retinoic acid induces expression of the thyroid hormone transporter, monocarboxylate transporter 8 (Mct8). J Biol Chem. 2010 Aug 27; 285(35):27279-27288. Kogai T, Liu YY, Richter LL, Mody K, Kagechika H, Brent GA. PMID: 20573951; PMCID: PMC2930727.
      View in: PubMed   Mentions: 15     Fields:    Translation:AnimalsCells
    62. Thyroid hormone crosstalk with nuclear receptor signaling in metabolic regulation. Trends Endocrinol Metab. 2010 Mar; 21(3):166-73. Liu YY, Brent GA. PMID: 20015660; PMCID: PMC2831161.
      View in: PubMed   Mentions: 72     Fields:    Translation:HumansAnimalsCells
    63. Expression of uncoupling protein 1 in mouse brown adipose tissue is thyroid hormone receptor-beta isoform specific and required for adaptive thermogenesis. Endocrinology. 2010 Jan; 151(1):432-40. Ribeiro MO, Bianco SD, Kaneshige M, Schultz JJ, Cheng SY, Bianco AC, Brent GA. PMID: 19906816; PMCID: PMC2817565.
      View in: PubMed   Mentions: 52     Fields:    Translation:AnimalsCells
    64. Activation of the PI3 kinase pathway by retinoic acid mediates sodium/iodide symporter induction and iodide transport in MCF-7 breast cancer cells. Cancer Res. 2009 Apr 15; 69(8):3443-50. Ohashi E, Kogai T, Kagechika H, Brent GA. PMID: 19351850; PMCID: PMC2852426.
      View in: PubMed   Mentions: 21     Fields:    Translation:HumansAnimalsCells
    65. Phosphoinositide-3-kinase inhibition induces sodium/iodide symporter expression in rat thyroid cells and human papillary thyroid cancer cells. J Endocrinol. 2008 Nov; 199(2):243-52. Kogai T, Sajid-Crockett S, Newmarch LS, Liu YY, Brent GA. PMID: 18762555.
      View in: PubMed   Mentions: 51     Fields:    Translation:HumansAnimalsCells
    66. Clinical practice. Graves' disease. N Engl J Med. 2008 Jun 12; 358(24):2594-605. Brent GA. PMID: 18550875.
      View in: PubMed   Mentions: 169     Fields:    Translation:Humans
    67. Stealth sequences in reporter gene vectors confound studies of T3-regulated negative gene expression. Thyroid. 2008 Jun; 18(6):593-5. Liu YY, Brent GA. PMID: 18578606.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimalsCells
    68. Retinoic acid stimulation of the sodium/iodide symporter in MCF-7 breast cancer cells is mediated by the insulin growth factor-I/phosphatidylinositol 3-kinase and p38 mitogen-activated protein kinase signaling pathways. J Clin Endocrinol Metab. 2008 May; 93(5):1884-92. Kogai T, Ohashi E, Jacobs MS, Sajid-Crockett S, Fisher ML, Kanamoto Y, Brent GA. PMID: 18319322; PMCID: PMC2386284.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansCells
    69. Thyroid health and the environment. Thyroid. 2007 Sep; 17(9):807-9. Brent GA, Braverman LE, Zoeller RT. PMID: 17956154.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansPHPublic Health
    70. Diagnosing thyroid dysfunction in pregnant women: Is case finding enough? J Clin Endocrinol Metab. 2007 Jan; 92(1):39-41. Brent GA. PMID: 17209222.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    71. Thyroid hormone regulates endogenous amyloid-beta precursor protein gene expression and processing in both in vitro and in vivo models. Thyroid. 2006 Dec; 16(12):1207-13. O'Barr SA, Oh JS, Ma C, Brent GA, Schultz JJ. PMID: 17199430.
      View in: PubMed   Mentions: 22     Fields:    Translation:HumansAnimalsCells
    72. A mutant thyroid hormone receptor alpha antagonizes peroxisome proliferator-activated receptor alpha signaling in vivo and impairs fatty acid oxidation. Endocrinology. 2007 Mar; 148(3):1206-17. Liu YY, Heymann RS, Moatamed F, Schultz JJ, Sobel D, Brent GA. PMID: 17122078.
      View in: PubMed   Mentions: 33     Fields:    Translation:AnimalsCells
    73. Anaplastic thyroid carcinoma with thyrotoxicosis and hypoparathyroidism. Endocr Pract. 2005 Jul-Aug; 11(4):281-4. Heymann RS, Brent GA, Hershman JM. PMID: 16006301.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    74. Differential regulation of sodium/iodide symporter gene expression by nuclear receptor ligands in MCF-7 breast cancer cells. Endocrinology. 2005 Jul; 146(7):3059-69. Kogai T, Kanamoto Y, Li AI, Che LH, Ohashi E, Taki K, Chandraratna RA, Saito T, Brent GA. PMID: 15817668.
      View in: PubMed   Mentions: 21     Fields:    Translation:HumansCells
    75. Rapid progression from subclinical to symptomatic overt hypothyroidism. Endocr Pract. 2005 Mar-Apr; 11(2):115-9. Heymann R, Brent GA. PMID: 15901527.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    76. Resistance to thyroid hormone in Hashimoto's thyroiditis. N Engl J Med. 2005 Feb 03; 352(5):517-8. Fukata S, Brent GA, Sugawara M. PMID: 15689599.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    77. Introduction. The impact of maternal thyroid diseases on the developing fetus: implications for diagnosis, treatment, and screening. Summary of proceedings, workshop organization, program, and participants. Thyroid. 2005 Jan; 15(1):36-40. Brent G, Boyle CA. PMID: 15687821.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    78. Regulation of regional expression in rat brain PC2 by thyroid hormone/characterization of novel negative thyroid hormone response elements in the PC2 promoter. Am J Physiol Endocrinol Metab. 2005 Jan; 288(1):E236-45. Shen X, Li QL, Brent GA, Friedman TC. PMID: 15585599.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    79. Thyroid function inside and outside of pregnancy: what do we know and what don't we know? Thyroid. 2005 Jan; 15(1):54-9. Smallridge RC, Glinoer D, Hollowell JG, Brent G. PMID: 15687824.
      View in: PubMed   Mentions: 15     Fields:    Translation:Humans
    80. Thyroid hormone-dependent gene expression in differentiated embryonic stem cells and embryonal carcinoma cells: identification of novel thyroid hormone target genes by deoxyribonucleic acid microarray analysis. Endocrinology. 2005 Feb; 146(2):776-83. Liu YY, Brent GA. PMID: 15550503.
      View in: PubMed   Mentions: 7     Fields:    Translation:AnimalsCells
    81. Systemic retinoic acid treatment induces sodium/iodide symporter expression and radioiodide uptake in mouse breast cancer models. Cancer Res. 2004 Jan 01; 64(1):415-22. Kogai T, Kanamoto Y, Che LH, Taki K, Moatamed F, Schultz JJ, Brent GA. PMID: 14729653.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansAnimalsCells
    82. Enhanced expression of nicotinamide N-methyltransferase in human papillary thyroid carcinoma cells. J Clin Endocrinol Metab. 2003 Oct; 88(10):4990-6. Xu J, Moatamed F, Caldwell JS, Walker JR, Kraiem Z, Taki K, Brent GA, Hershman JM. PMID: 14557485.
      View in: PubMed   Mentions: 34     Fields:    Translation:HumansCells
    83. Spared bone mass in rats treated with thyroid hormone receptor TR beta-selective compound GC-1. Am J Physiol Endocrinol Metab. 2003 Nov; 285(5):E1135-41. Freitas FR, Moriscot AS, Jorgetti V, Soares AG, Passarelli M, Scanlan TS, Brent GA, Bianco AC, Gouveia CH. PMID: 12965872.
      View in: PubMed   Mentions: 22     Fields:    Translation:Animals
    84. Follow-up of newborns with elevated screening T4 concentrations. J Pediatr. 2003 Sep; 143(3):296-301. Lafranchi SH, Snyder DB, Sesser DE, Skeels MR, Singh N, Brent GA, Nelson JC. PMID: 14517508.
      View in: PubMed   Mentions: 44     Fields:    Translation:HumansPHPublic Health
    85. Nonradioactive iodide effectively induces apoptosis in genetically modified lung cancer cells. Cancer Res. 2003 Aug 15; 63(16):5065-72. Zhang L, Sharma S, Zhu LX, Kogai T, Hershman JM, Brent GA, Dubinett SM, Huang M. PMID: 12941836.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansAnimalsCells
    86. A thyroid hormone receptor alpha gene mutation (P398H) is associated with visceral adiposity and impaired catecholamine-stimulated lipolysis in mice. J Biol Chem. 2003 Oct 03; 278(40):38913-20. Liu YY, Schultz JJ, Brent GA. PMID: 12869545.
      View in: PubMed   Mentions: 50     Fields:    Translation:AnimalsCells
    87. The modified firefly luciferase reporter gene (luc+) but not Renilla luciferase is induced by all-trans retinoic acid in MCF-7 breast cancer cells. Breast Cancer Res Treat. 2003 Mar; 78(1):119-26. Kogai T, Kanamoto Y, Brent GA. PMID: 12611464.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansAnimalsCells
    88. Thyroid hormone gene targets in ROS 17/2.8 osteoblast-like cells identified by differential display analysis. Thyroid. 2002 Aug; 12(8):663-71. Gouveia CH, Schultz JJ, Jackson DJ, Williams GR, Brent GA. PMID: 12225634.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    89. A GC box in the human sodium iodide symporter gene promoter is essential for full activity. Thyroid. 2002 Feb; 12(2):107-14. Xu J, Kogai T, Brent GA, Hershman JM. PMID: 11916279.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimalsCells
    90. The Kaposi sarcoma-associated herpesvirus (KSHV) induces cellular interleukin 6 expression: role of the KSHV latency-associated nuclear antigen and the AP1 response element. Blood. 2002 Jan 15; 99(2):649-54. An J, Lichtenstein AK, Brent G, Rettig MB. PMID: 11781250.
      View in: PubMed   Mentions: 49     Fields:    Translation:HumansCells
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