Amiya P Sinha-Hikim

Title(s)Professor-in-Residence, Medicine
SchoolMedicine
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Hepatic steatosis induced by nicotine plus Coca-Cola™ is prevented by nicotinamide riboside (NR). Front Endocrinol (Lausanne). 2024; 15:1282231. Rivera JC, Espinoza-Derout J, Hasan KM, Molina-Mancio J, Martínez J, Lao CJ, Lee ML, Lee DL, Wilson J, Sinha-Hikim AP, Friedman TC. PMID: 38756999; PMCID: PMC11097688.
      View in: PubMed   Mentions:    Fields:    Translation:Animals
    2. The lipolysis inhibitor acipimox reverses the cardiac phenotype induced by electronic cigarettes. Sci Rep. 2023 10 25; 13(1):18239. Espinoza-Derout J, Arambulo JML, Ramirez-Trillo W, Rivera JC, Hasan KM, Lao CJ, Jordan MC, Shao XM, Roos KP, Sinha-Hikim AP, Friedman TC. PMID: 37880325; PMCID: PMC10600141.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    3. Fatty Acid Excess Dysregulates CARF to Initiate the Development of Hepatic Steatosis. Cells. 2023 04 01; 12(7). Hasan KM, Parveen M, Pena A, Bautista F, Rivera JC, Huerta RR, Martinez E, Espinoza-Derout J, Sinha-Hikim AP, Friedman TC. PMID: 37048142; PMCID: PMC10093423.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    4. Electronic Cigarette Use and the Risk of Cardiovascular Diseases. Front Cardiovasc Med. 2022; 9:879726. Espinoza-Derout J, Shao XM, Lao CJ, Hasan KM, Rivera JC, Jordan MC, Echeverria V, Roos KP, Sinha-Hikim AP, Friedman TC. PMID: 35463745; PMCID: PMC9021536.
      View in: PubMed   Mentions: 23  
    5. Unhealthy Lifestyle and Gut Dysbiosis: A Better Understanding of the Effects of Poor Diet and Nicotine on the Intestinal Microbiome. Front Endocrinol (Lausanne). 2021; 12:667066. Martinez JE, Kahana DD, Ghuman S, Wilson HP, Wilson J, Kim SCJ, Lagishetty V, Jacobs JP, Sinha-Hikim AP, Friedman TC. PMID: 34168615; PMCID: PMC8218903.
      View in: PubMed   Mentions: 67     Fields:    Translation:Humans
    6. Adverse effects of fetal exposure of electronic-cigarettes and high-fat diet on male neonatal hearts. Exp Mol Pathol. 2021 02; 118:104573. Hasan KM, Munoz A, Tumoyan H, Parveen M, Espinoza-Derout J, Shao XM, Mahata SK, Friedman TC, Sinha-Hikim AP. PMID: 33212125; PMCID: PMC8501912.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    7. Electronic cigarettes cause alteration in cardiac structure and function in diet-induced obese mice. PLoS One. 2020; 15(10):e0239671. Hasan KM, Friedman TC, Parveen M, Espinoza-Derout J, Bautista F, Razipour MM, Shao XM, Jordan MC, Roos KP, Mahata SK, Sinha-Hikim AP. PMID: 33002059; PMCID: PMC7529198.
      View in: PubMed   Mentions: 10     Fields:    Translation:Animals
    8. A mouse model for chronic intermittent electronic cigarette exposure exhibits nicotine pharmacokinetics resembling human vapers. J Neurosci Methods. 2019 10 01; 326:108376. Shao XM, Lopez B, Nathan D, Wilson J, Bankole E, Tumoyan H, Munoz A, Espinoza-Derout J, Hasan KM, Chang S, Du C, Sinha-Hikim AP, Lutfy K, Friedman TC. PMID: 31361999; PMCID: PMC6717674.
      View in: PubMed   Mentions: 24     Fields:    Translation:Animals
    9. Chronic intermittent electronic cigarette exposure induces cardiac dysfunction and atherosclerosis in apolipoprotein-E knockout mice. Am J Physiol Heart Circ Physiol. 2019 08 01; 317(2):H445-H459. Espinoza-Derout J, Hasan KM, Shao XM, Jordan MC, Sims C, Lee DL, Sinha S, Simmons Z, Mtume N, Liu Y, Roos KP, Sinha-Hikim AP, Friedman TC. PMID: 31172811; PMCID: PMC6732484.
      View in: PubMed   Mentions: 44     Fields:    Translation:AnimalsCellsPHPublic Health
    10. Hepatic DNA Damage Induced by Electronic Cigarette Exposure Is Associated With the Modulation of NAD+/PARP1/SIRT1 Axis. Front Endocrinol (Lausanne). 2019; 10:320. Espinoza-Derout J, Shao XM, Bankole E, Hasan KM, Mtume N, Liu Y, Sinha-Hikim AP, Friedman TC. PMID: 31214115; PMCID: PMC6558099.
      View in: PubMed   Mentions: 15     Fields:    
    11. E-cigarettes and Western Diet: Important Metabolic Risk Factors for Hepatic Diseases. Hepatology. 2019 06; 69(6):2442-2454. Hasan KM, Friedman TC, Shao X, Parveen M, Sims C, Lee DL, Espinoza-Derout J, Sinha-Hikim I, Sinha-Hikim AP. PMID: 30664268; PMCID: PMC6636679.
      View in: PubMed   Mentions: 23     Fields:    Translation:HumansAnimals
    12. α7-Nicotinic Acetylcholine Receptor Agonist Ameliorates Nicotine Plus High-Fat Diet-Induced Hepatic Steatosis in Male Mice by Inhibiting Oxidative Stress and Stimulating AMPK Signaling. Endocrinology. 2018 02 01; 159(2):931-944. Hasan MK, Friedman TC, Sims C, Lee DL, Espinoza-Derout J, Ume A, Chalfant V, Lee ML, Sinha-Hikim I, Lutfy K, Liu Y, Mahata SK, Sinha-Hikim AP. PMID: 29272360; PMCID: PMC5776480.
      View in: PubMed   Mentions: 14     Fields:    Translation:AnimalsCells
    13. Editorial: Obesity, Smoking, and Fatty Liver Disease. Front Endocrinol (Lausanne). 2018; 9:1. Sinha-Hikim AP, Mahata SK. PMID: 29403440; PMCID: PMC5778120.
      View in: PubMed   Mentions: 1     Fields:    
    14. Connection of Nicotine to Diet-Induced Obesity and Non-Alcoholic Fatty Liver Disease: Cellular and Mechanistic Insights. Front Endocrinol (Lausanne). 2017; 8:23. Sinha-Hikim AP, Sinha-Hikim I, Friedman TC. PMID: 28239368; PMCID: PMC5300964.
      View in: PubMed   Mentions: 21     Fields:    
    15. Nicotine plus a high-fat diet triggers cardiomyocyte apoptosis. Cell Tissue Res. 2017 04; 368(1):159-170. Sinha-Hikim I, Friedman TC, Falz M, Chalfant V, Hasan MK, Espinoza-Derout J, Lee DL, Sims C, Tran P, Mahata SK, Sinha-Hikim AP. PMID: 27917437; PMCID: PMC5813800.
      View in: PubMed   Mentions: 14     Fields:    Translation:AnimalsCells
    16. Muscle injury, impaired muscle function and insulin resistance in Chromogranin A-knockout mice. J Endocrinol. 2017 02; 232(2):137-153. Tang K, Pasqua T, Biswas A, Mahata S, Tang J, Tang A, Bandyopadhyay GK, Sinha-Hikim AP, Chi NW, Webster NJ, Corti A, Mahata SK. PMID: 27799464; PMCID: PMC5287349.
      View in: PubMed   Mentions: 5     Fields:    Translation:AnimalsCells
    17. Erratum to: Impact of Chromogranin A deficiency on catecholamine storage, catecholamine granule morphology and chromaffin cell energy metabolism in vivo. Cell Tissue Res. 2016 Mar; 363(3):823. Pasqua T, Mahata S, Bandyopadhyay GK, Biswas A, Perkins GA, Sinha-Hikim AP, Goldstein DS, Eiden LE, Mahata SK. PMID: 26809511; PMCID: PMC5585018.
      View in: PubMed   Mentions:    Fields:    
    18. Impact of Chromogranin A deficiency on catecholamine storage, catecholamine granule morphology and chromaffin cell energy metabolism in vivo. Cell Tissue Res. 2016 Mar; 363(3):693-712. Pasqua T, Mahata S, Bandyopadhyay GK, Biswas A, Perkins GA, Sinha-Hikim AP, Goldstein DS, Eiden LE, Mahata SK. PMID: 26572539; PMCID: PMC5529139.
      View in: PubMed   Mentions: 23     Fields:    Translation:HumansAnimalsCells
    19. Testosterone is essential for skeletal muscle growth in aged mice in a heterochronic parabiosis model. Cell Tissue Res. 2014 Sep; 357(3):815-21. Sinha I, Sinha-Hikim AP, Wagers AJ, Sinha-Hikim I. PMID: 24859218; PMCID: PMC4149819.
      View in: PubMed   Mentions: 23     Fields:    Translation:AnimalsCells
    20. Additive effects of nicotine and high-fat diet on hepatocellular apoptosis in mice: involvement of caspase 2 and inducible nitric oxide synthase-mediated intrinsic pathway signaling. Horm Metab Res. 2014 Jul; 46(8):568-73. Ivey R, Desai M, Green K, Sinha-Hikim I, Friedman TC, Sinha-Hikim AP. PMID: 24830635; PMCID: PMC4327908.
      View in: PubMed   Mentions: 13     Fields:    Translation:AnimalsCells
    21. Nicotine in combination with a high-fat diet causes intramyocellular mitochondrial abnormalities in male mice. Endocrinology. 2014 Mar; 155(3):865-72. Sinha-Hikim I, Friedman TC, Shin CS, Lee D, Ivey R, Sinha-Hikim AP. PMID: 24424058; PMCID: PMC3929732.
      View in: PubMed   Mentions: 17     Fields:    Translation:AnimalsCells
    22. Long-term supplementation with a cystine-based antioxidant delays loss of muscle mass in aging. J Gerontol A Biol Sci Med Sci. 2013 Jul; 68(7):749-59. Sinha-Hikim I, Sinha-Hikim AP, Parveen M, Shen R, Goswami R, Tran P, Crum A, Norris KC. PMID: 23459206; PMCID: PMC3674717.
      View in: PubMed   Mentions: 28     Fields:    Translation:Animals
    23. Additive effects of nicotine and high-fat diet on hepatic steatosis in male mice. Endocrinology. 2012 Dec; 153(12):5809-20. Friedman TC, Sinha-Hikim I, Parveen M, Najjar SM, Liu Y, Mangubat M, Shin CS, Lyzlov A, Ivey R, Shaheen M, French SW, Sinha-Hikim AP. PMID: 23093702; PMCID: PMC3512067.
      View in: PubMed   Mentions: 32     Fields:    Translation:AnimalsCells
    24. Interaction between microRNAs and actin-associated protein Arpc5 regulates translational suppression during male germ cell differentiation. Proc Natl Acad Sci U S A. 2012 Apr 10; 109(15):5750-5. Chang YF, Lee-Chang JS, Imam JS, Buddavarapu KC, Subaran SS, Sinha-Hikim AP, Gorospe M, Rao MK. PMID: 22447776; PMCID: PMC3326518.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansAnimalsCells
    25. Effect of nicotine on body composition in mice. J Endocrinol. 2012 Mar; 212(3):317-26. Mangubat M, Lutfy K, Lee ML, Pulido L, Stout D, Davis R, Shin CS, Shahbazian M, Seasholtz S, Sinha-Hikim A, Sinha-Hikim I, O'Dell LE, Lyzlov A, Liu Y, Friedman TC. PMID: 22138237; PMCID: PMC3444240.
      View in: PubMed   Mentions: 33     Fields:    Translation:Animals
    26. Role of β-catenin in post-meiotic male germ cell differentiation. PLoS One. 2011; 6(11):e28039. Chang YF, Lee-Chang JS, Harris KY, Sinha-Hikim AP, Rao MK. PMID: 22125654; PMCID: PMC3220672.
      View in: PubMed   Mentions: 18     Fields:    Translation:AnimalsCells
    27. Minocycline suppresses oxidative stress and attenuates fetal cardiac myocyte apoptosis triggered by in utero cocaine exposure. Apoptosis. 2011 Jun; 16(6):563-73. Sinha-Hikim I, Shen R, Nzenwa I, Gelfand R, Mahata SK, Sinha-Hikim AP. PMID: 21424555; PMCID: PMC4701037.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansAnimalsCellsPHPublic Health
    28. A novel cystine based antioxidant attenuates oxidative stress and hepatic steatosis in diet-induced obese mice. Exp Mol Pathol. 2011 Aug; 91(1):419-28. Sinha-Hikim I, Sinha-Hikim AP, Shen R, Kim HJ, Kim H, French SW, Vaziri ND, Vaziri ND, Crum AC, Crum A, Rajavashisth TB, Norris KC. PMID: 21570964; PMCID: PMC3191382.
      View in: PubMed   Mentions: 24     Fields:    Translation:AnimalsCells
    29. Mitogen-activated protein kinase signaling in male germ cell apoptosis in the rat. Biol Reprod. 2009 Apr; 80(4):771-80. Jia Y, Castellanos J, Wang C, Sinha-Hikim I, Lue Y, Swerdloff RS, Sinha-Hikim AP. PMID: 19109224; PMCID: PMC2804830.
      View in: PubMed   Mentions: 23     Fields:    Translation:AnimalsCells
    30. Tissue-specific RNAi reveals that WT1 expression in nurse cells controls germ cell survival and spermatogenesis. Genes Dev. 2006 Jan 15; 20(2):147-52. Rao MK, Pham J, Imam JS, MacLean JA, Murali D, Furuta Y, Sinha-Hikim AP, Wilkinson MF. PMID: 16418481; PMCID: PMC1356106.
      View in: PubMed   Mentions: 50     Fields:    Translation:AnimalsCells
    31. Mouse model of male germ cell apoptosis in response to a lack of hormonal stimulation. Indian J Exp Biol. 2005 Nov; 43(11):1048-57. Hikim AP, Vera Y, Elhag RI, Lue Y, Cui YG, Pope V, Leung A, Atienza V, Wang C, Swerdloff RS. PMID: 16315394.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    32. Mitochondrial-dependent apoptosis in experimental rodent abdominal aortic aneurysms. Surgery. 2005 Oct; 138(4):806-11. Sinha I, Sinha-Hikim AP, Hannawa KK, Henke PK, Eagleton MJ, Stanley JC, Upchurch GR. PMID: 16269312.
      View in: PubMed   Mentions: 12     Fields:    Translation:AnimalsCells
    33. In the male brown-Norway (BN) male rat, reproductive aging is associated with decreased LH-pulse amplitude and area. J Androl. 1997 Jul-Aug; 18(4):359-65. Bonavera JJ, Swerdloff RS, Leung A, Lue YH, Baravarian S, Superlano L, Sinha-Hikim AP, Wang C. PMID: 9283947.
      View in: PubMed   Mentions: 12     Fields:    Translation:Animals
    34. The anti-progestin CDB 2914 has no antifertility effect in male rats. Contraception. 1995 Mar; 51(3):215-8. Wang C, Sinha-Hikim A, Leung A. PMID: 7621692.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    35. Reproductive aging in the male brown-Norway rat: a model for the human. Endocrinology. 1993 Dec; 133(6):2773-81. Wang C, Leung A, Sinha-Hikim AP. PMID: 8243304.
      View in: PubMed   Mentions: 40     Fields:    Translation:AnimalsCells
    36. Temporal and stage-specific changes in spermatogenesis of rat after gonadotropin deprivation by a potent gonadotropin-releasing hormone antagonist treatment. Endocrinology. 1993 Nov; 133(5):2161-70. Sinha-Hikim AP, Swerdloff RS. PMID: 8404667.
      View in: PubMed   Mentions: 13     Fields:    Translation:AnimalsCells
    37. Further observations of stage-specific effects seen after short-term hypophysectomy in the rat. Tissue Cell. 1991; 23(5):613-30. Ghosh S, Sinha-Hikim AP, Russell LD. PMID: 1776153.
      View in: PubMed   Mentions: 8     Fields:    Translation:AnimalsCells
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