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Hokugo, Akishige

Title(s)Assistant Adjunct Professor, Surgery
SchoolPlastic
Phone44737
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Bakshi R, Hokugo A, Zhou S, Zhang Z, Wang L, Rezzadeh K, Segovia LA, Jarrahy R. Application of Hydroxycholesterols for Alveolar Cleft Osteoplasty in a Rodent Model. Plast Reconstr Surg. 2019 05; 143(5):1385-1395. PMID: 30789479.
      View in: PubMed
    2. Zhou S, Hokugo A, McClendon M, Zhang Z, Bakshi R, Wang L, Segovia LA, Rezzadeh K, Stupp SI, Jarrahy R. Bioactive peptide amphiphile nanofiber gels enhance burn wound healing. Burns. 2019 08; 45(5):1112-1121. PMID: 31043333.
      View in: PubMed
    3. Hokugo A, Kanayama K, Sun S, Morinaga K, Sun Y, Wu Q, Sasaki H, Okawa H, Evans C, Ebetino FH, Lundy MW, Sadrerafi K, McKenna CE, Nishimura I. Rescue bisphosphonate treatment of alveolar bone improves extraction socket healing and reduces osteonecrosis in zoledronate-treated mice. Bone. 2019 06; 123:115-128. PMID: 30926440.
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    4. Sasaki H, Hokugo A, Wang L, Morinaga K, Ngo JT, Okawa H, Nishimura I. Neuronal PAS Domain 2 (Npas2)-Deficient Fibroblasts Accelerate Skin Wound Healing and Dermal Collagen Reconstruction. Anat Rec (Hoboken). 2019 Mar 09. PMID: 30851151.
      View in: PubMed
    5. Morinaga K, Sasaki H, Park S, Hokugo A, Okawa H, Tahara Y, Colwell CS, Nishimura I. Neuronal PAS domain 2 (Npas2) facilitated osseointegration of titanium implant with rough surface through a neuroskeletal mechanism. Biomaterials. 2019 02; 192:62-74. PMID: 30428407.
      View in: PubMed
    6. Hsu JJ, Lu J, Umar S, Lee JT, Kulkarni RP, Ding Y, Chang CC, Hsiai TK, Hokugo A, Gkouveris I, Tetradis S, Nishimura I, Demer LL, Tintut Y. Effects of teriparatide on morphology of aortic calcification in aged hyperlipidemic mice. Am J Physiol Heart Circ Physiol. 2018 06 01; 314(6):H1203-H1213. PMID: 29451816.
      View in: PubMed
    7. Hassan N, McCarville K, Morinaga K, Mengatto CM, Langfelder P, Hokugo A, Tahara Y, Colwell CS, Nishimura I. Titanium biomaterials with complex surfaces induced aberrant peripheral circadian rhythms in bone marrow mesenchymal stromal cells. PLoS One. 2017; 12(8):e0183359. PMID: 28817668.
      View in: PubMed
    8. Subbiah N, Campagna J, Spilman P, Alam MP, Sharma S, Hokugo A, Nishimura I, John V. Deformable Nanovesicles Synthesized through an Adaptable Microfluidic Platform for Enhanced Localized Transdermal Drug Delivery. J Drug Deliv. 2017; 2017:4759839. PMID: 28480080.
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    9. Sun Y, Kaur K, Kanayama K, Morinaga K, Park S, Hokugo A, Kozlowska A, McBride WH, Li J, Jewett A, Nishimura I. Plasticity of Myeloid Cells during Oral Barrier Wound Healing and the Development of Bisphosphonate-related Osteonecrosis of the Jaw. J Biol Chem. 2016 09 23; 291(39):20602-16. PMID: 27514746.
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    10. Rezzadeh KS, Hokugo A, Jewett A, Kozlowska A, Segovia LA, Zuk P, Jarrahy R. Natural Killer Cells Differentiate Human Adipose-Derived Stem Cells and Modulate Their Adipogenic Potential. Plast Reconstr Surg. 2015 Sep; 136(3):503-10. PMID: 26313823.
      View in: PubMed
    11. Li A, Hokugo A, Segovia LA, Yalom A, Rezzadeh K, Zhou S, Zhang Z, Parhami F, Stappenbeck F, Jarrahy R. Oxy133, a novel osteogenic agent, promotes bone regeneration in an intramembranous bone-healing model. J Tissue Eng Regen Med. 2017 05; 11(5):1490-1499. PMID: 26073881.
      View in: PubMed
    12. Hokugo A, Li A, Segovia LA, Yalom A, Rezzadeh K, Zhou S, Zhang Z, Zuk PA, Jarrahy R. Development of chemotactic smart scaffold for use in tissue regeneration. Plast Reconstr Surg. 2015 May; 135(5):877e-884e. PMID: 25919270.
      View in: PubMed
    13. Yamamoto M, Hokugo A, Takahashi Y, Nakano T, Hiraoka M, Tabata Y. Combination of BMP-2-releasing gelatin/ß-TCP sponges with autologous bone marrow for bone regeneration of X-ray-irradiated rabbit ulnar defects. Biomaterials. 2015 Jul; 56:18-25. PMID: 25934275.
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    14. Yalom A, Hokugo A, Sorice S, Li A, Segovia Aguilar LA, Zuk P, Jarrahy R. In vitro osteoinductive effects of hydroxycholesterol on human adipose-derived stem cells are mediated through the hedgehog signaling pathway. Plast Reconstr Surg. 2014 Nov; 134(5):960-8. PMID: 25347631.
      View in: PubMed
    15. Montgomery SR, Nargizyan T, Meliton V, Nachtergaele S, Rohatgi R, Stappenbeck F, Jung ME, Johnson JS, Aghdasi B, Tian H, Weintraub G, Inoue H, Atti E, Tetradis S, Pereira RC, Hokugo A, Alobaidaan R, Tan Y, Hahn TJ, Wang JC, Parhami F. A novel osteogenic oxysterol compound for therapeutic development to promote bone growth: activation of hedgehog signaling and osteogenesis through smoothened binding. J Bone Miner Res. 2014 Aug; 29(8):1872-85. PMID: 24591126.
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    16. Li A, Hokugo A, Yalom A, Berns EJ, Stephanopoulos N, McClendon MT, Segovia LA, Spigelman I, Stupp SI, Jarrahy R. A bioengineered peripheral nerve construct using aligned peptide amphiphile nanofibers. Biomaterials. 2014 Oct; 35(31):8780-8790. PMID: 25064803.
      View in: PubMed
    17. Hokugo A, Saito T, Li A, Sato K, Tabata Y, Jarrahy R. Stimulation of bone regeneration following the controlled release of water-insoluble oxysterol from biodegradable hydrogel. Biomaterials. 2014 Jul; 35(21):5565-71. PMID: 24731715.
      View in: PubMed
    18. Hokugo A, Sorice S, Parhami F, Yalom A, Li A, Zuk P, Jarrahy R. A novel oxysterol promotes bone regeneration in rabbit cranial bone defects. J Tissue Eng Regen Med. 2016 07; 10(7):591-9. PMID: 23997014.
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    19. Hokugo A, Sorice S, Yalom A, Lee JC, Li A, Zuk P, Jarrahy R. In vitro study of a novel oxysterol for osteogenic differentiation on rabbit bone marrow stromal cells. Plast Reconstr Surg. 2013 Jul; 132(1):70e-80e. PMID: 23806956.
      View in: PubMed
    20. Hokugo A, Sun S, Park S, McKenna CE, Nishimura I. Equilibrium-dependent bisphosphonate interaction with crystalline bone mineral explains anti-resorptive pharmacokinetics and prevalence of osteonecrosis of the jaw in rats. Bone. 2013 Mar; 53(1):59-68. PMID: 23219943.
      View in: PubMed
    21. Armin BB, Hokugo A, Nishimura I, Tamplen M, Beumer J, Steinberg ML, Abemayor E, Nabili V. Brachytherapy-mediated bone damage in a rat model investigating maxillary osteoradionecrosis. Arch Otolaryngol Head Neck Surg. 2012 Feb; 138(2):167-71. PMID: 22351863.
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    22. Hokugo A. [Vitamin D and bisphosphonate-related osteonecrosis of the jaw (BRONJ) ]. Clin Calcium. 2012 Jan; 22(1):83-90. PMID: 22201103.
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    23. Sawada Y, Hokugo A, Yang Y, Kamitani M, Matsuda S, Mao T, Lei D, Chen F, Iseki T, Morita S. A novel hydroxyapatite ceramic bone substitute transformed by ostrich cancellous bone: characterization and evaluations of bone regeneration activity. J Biomed Mater Res B Appl Biomater. 2011 Aug; 98(2):217-22. PMID: 21681951.
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    24. Reilly MJ, Cohen M, Hokugo A, Keller GS. Molecular effects of fractional carbon dioxide laser resurfacing on photodamaged human skin. Arch Facial Plast Surg. 2010 Sep-Oct; 12(5):321-5. PMID: 20855774.
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    25. Cohen M, Nishimura I, Tamplen M, Hokugo A, Beumer J, Steinberg ML, Suh JD, Abemayor E, Nabili V. Animal model of radiogenic bone damage to study mandibular osteoradionecrosis. Am J Otolaryngol. 2011 Jul-Aug; 32(4):291-300. PMID: 20719407.
      View in: PubMed
    26. Lin A, Hokugo A, Nishimura I. Wound closure and wound management: A new therapeutic molecular target. Cell Adh Migr. 2010 Jul-Sep; 4(3):396-9. PMID: 20448469.
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    27. Hokugo A, Christensen R, Chung EM, Sung EC, Felsenfeld AL, Sayre JW, Garrett N, Adams JS, Nishimura I. Increased prevalence of bisphosphonate-related osteonecrosis of the jaw with vitamin D deficiency in rats. J Bone Miner Res. 2010 Jun; 25(6):1337-49. PMID: 20200938.
      View in: PubMed
    28. Lin A, Hokugo A, Choi J, Nishimura I. Small cytoskeleton-associated molecule, fibroblast growth factor receptor 1 oncogene partner 2/wound inducible transcript-3.0 (FGFR1OP2/wit3.0), facilitates fibroblast-driven wound closure. Am J Pathol. 2010 Jan; 176(1):108-21. PMID: 19959814.
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    29. Sawada Y, Hokugo A, Nishiura A, Hokugo R, Matsumoto N, Morita S, Tabata Y. A trial of alveolar cleft bone regeneration by controlled release of bone morphogenetic protein: an experimental study in rabbits. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2009 Dec; 108(6):812-20. PMID: 19782619.
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    30. Wang CJ, Iida K, Egusa H, Hokugo A, Jewett A, Nishimura I. Trabecular bone deterioration in col9a1+/- mice associated with enlarged osteoclasts adhered to collagen IX-deficient bone. J Bone Miner Res. 2008 Jun; 23(6):837-49. PMID: 18251701.
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    31. Kimura Y, Hokugo A, Takamoto T, Tabata Y, Kurosawa H. Regeneration of anterior cruciate ligament by biodegradable scaffold combined with local controlled release of basic fibroblast growth factor and collagen wrapping. Tissue Eng Part C Methods. 2008 Mar; 14(1):47-57. PMID: 18454645.
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    32. Ishida K, Kuroda R, Miwa M, Tabata Y, Hokugo A, Kawamoto T, Sasaki K, Doita M, Kurosaka M. The regenerative effects of platelet-rich plasma on meniscal cells in vitro and its in vivo application with biodegradable gelatin hydrogel. Tissue Eng. 2007 May; 13(5):1103-12. PMID: 17348798.
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    33. Hokugo A, Sawada Y, Hokugo R, Iwamura H, Kobuchi M, Kambara T, Morita S, Tabata Y. Controlled release of platelet growth factors enhances bone regeneration at rabbit calvaria. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2007 Jul; 104(1):44-8. PMID: 17376715.
      View in: PubMed
    34. Hokugo A, Sawada Y, Sugimoto K, Fukuda A, Mushimoto K, Morita S, Tabata Y. Preparation of prefabricated vascularized bone graft with neoangiogenesis by combination of autologous tissue and biodegradable materials. Int J Oral Maxillofac Surg. 2006 Nov; 35(11):1034-40. PMID: 16965895.
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    35. Takaba K, Jiang C, Nemoto S, Saji Y, Ikeda T, Urayama S, Azuma T, Hokugo A, Tsutsumi S, Tabata Y, Komeda M. A combination of omental flap and growth factor therapy induces arteriogenesis and increases myocardial perfusion in chronic myocardial ischemia: evolving concept of biologic coronary artery bypass grafting. J Thorac Cardiovasc Surg. 2006 Oct; 132(4):891-99. PMID: 17000302.
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    36. Hokugo A, Takamoto T, Tabata Y. Preparation of hybrid scaffold from fibrin and biodegradable polymer fiber. Biomaterials. 2006 Jan; 27(1):61-7. PMID: 16000222.
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    37. Hokugo A, Ozeki M, Kawakami O, Sugimoto K, Mushimoto K, Morita S, Tabata Y. Augmented bone regeneration activity of platelet-rich plasma by biodegradable gelatin hydrogel. Tissue Eng. 2005 Jul-Aug; 11(7-8):1224-33. PMID: 16144458.
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    38. Hokugo A, Kubo Y, Takahashi Y, Fukuda A, Horiuchi K, Mushimoto K, Morita S, Tabata Y. Prefabrication of vascularized bone graft using guided bone regeneration. Tissue Eng. 2004 Jul-Aug; 10(7-8):978-86. PMID: 15363155.
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