Yucheng Yao

Title(s)Professor-in-Residence, Medicine
SchoolMedicine
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    Switch of Osteogenesis in Vascular Calcification
    NIH R01HL139675Jul 1, 2018 - Jun 30, 2022
    Role: Principal Investigator
    BMP and Notch crosstalk in cerebral arteriovenous malformations
    NIH R01NS079353Jun 1, 2012 - May 31, 2022
    Role: Principal Investigator

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. The Mechanobiology of Endothelial-to-Mesenchymal Transition in Cardiovascular Disease. Front Physiol. 2021; 12:734215. Islam S, Boström KI, Di Carlo D, Simmons CA, Tintut Y, Yao Y, Hsu JJ. PMID: 34566697; PMCID: PMC8458763.
      View in: PubMed   Mentions:
    2. Shifting osteogenesis in vascular calcification. JCI Insight. 2021 May 24; 6(10). Yao J, Wu X, Qiao X, Zhang D, Zhang L, Ma JA, Cai X, Boström KI, Yao Y. PMID: 33848269.
      View in: PubMed   Mentions:    Fields:    
    3. Contributions of the Endothelium to Vascular Calcification. Front Cell Dev Biol. 2021; 9:620882. Zhang L, Yao J, Yao Y, Boström KI. PMID: 34079793.
      View in: PubMed   Mentions:
    4. Pronethalol Reduces Sox2 (SRY [Sex-Determining Region Y]-Box 2) to Ameliorate Vascular Calcification. Arterioscler Thromb Vasc Biol. 2021 02; 41(2):931-933. Zhang D, Qiao X, Yao J, Zhang L, Wu X, Ma J, Cai X, Bostrom KI, Yao Y. PMID: 33297753.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    5. Shaping Waves of Bone Morphogenetic Protein Inhibition During Vascular Growth. Circ Res. 2020 10 23; 127(10):1288-1305. Guihard PJ, Guo Y, Wu X, Zhang L, Yao J, Jumabay M, Yao Y, Garfinkel A, Boström KI. PMID: 32854559.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimals
    6. Pronethalol decreases RBPJκ to reduce Sox2 in cerebral arteriovenous malformation. Vasc Med. 2020 12; 25(6):569-571. Qiao X, Zhang D, Zhang L, Yao J, Wu X, Cai X, Boström KI, Yao Y. PMID: 32833597.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    7. Options for COVID-19 Entry into Pulmonary Cells. Biomed J Sci Tech Res. 2020 Aug; 29(2):22337-22338. Boström KI, Yao Y. PMID: 33283173.
      View in: PubMed   Mentions:
    8. Homeobox D3, A Novel Link Between Bone Morphogenetic Protein 9 and Transforming Growth Factor Beta 1 Signaling. J Mol Biol. 2020 03 27; 432(7):2030-2041. Wang L, Yao J, Yu T, Zhang D, Qiao X, Yao Z, Wu X, Zhang L, Boström KI, Yao Y. PMID: 32061928.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    9. Skip is essential for Notch signaling to induce Sox2 in cerebral arteriovenous malformations. Cell Signal. 2020 04; 68:109537. Zhang D, Qiao X, Wang L, Zhang L, Yao J, Wu X, Yu T, Boström KI, Yao Y. PMID: 31927035.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    10. Elevated endothelial Sox2 causes lumen disruption and cerebral arteriovenous malformations. J Clin Invest. 2019 06 24; 129(8):3121-3133. Yao J, Wu X, Zhang D, Wang L, Zhang L, Reynolds EX, Hernandez C, Boström KI, Yao Y. PMID: 31232700.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansAnimalsCells
    11. Crosstalk between BMP and Notch Induces Sox2 in Cerebral Endothelial Cells. Cells. 2019 06 06; 8(6). Wu X, Yao J, Wang L, Zhang D, Zhang L, Reynolds EX, Yu T, Boström KI, Yao Y. PMID: 31174355.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimalsCells
    12. Noggin depletion in adipocytes promotes obesity in mice. Mol Metab. 2019 07; 25:50-63. Blázquez-Medela AM, Jumabay M, Rajbhandari P, Sallam T, Guo Y, Yao J, Vergnes L, Reue K, Zhang L, Yao Y, Fogelman AM, Tontonoz P, Lusis AJ, Wu X, Boström KI. PMID: 31027994.
      View in: PubMed   Mentions: 5     Fields:    Translation:AnimalsCells
    13. SOX Transcription Factors in Endothelial Differentiation and Endothelial-Mesenchymal Transitions. Front Cardiovasc Med. 2019; 6:30. Yao Y, Yao J, Boström KI. PMID: 30984768.
      View in: PubMed   Mentions:
    14. Endothelial Cells May Have Tissue-Specific Origins. J Cell Biol Histol. 2018 Jun; 1(1). Boström KI, Yao J, Wu X, Yao Y. PMID: 29974893.
      View in: PubMed   Mentions:
    15. Vascular endothelium plays a key role in directing pulmonary epithelial cell differentiation. J Cell Biol. 2017 10 02; 216(10):3369-3385. Yao J, Guihard PJ, Wu X, Blazquez-Medela AM, Spencer MJ, Jumabay M, Tontonoz P, Fogelman AM, Boström KI, Yao Y. PMID: 28838957.
      View in: PubMed   Mentions: 8     Fields:    Translation:AnimalsCells
    16. Combined effects of bone morphogenetic protein 10 and crossveinless-2 on cardiomyocyte differentiation in mouse adipocyte-derived stem cells. J Cell Physiol. 2018 Mar; 233(3):1812-1822. Jumabay M, Zhumabai J, Mansurov N, Niklason KC, Guihard PJ, Cubberly MR, Fogelman AM, Iruela-Arispe L, Yao Y, Saparov A, Boström KI. PMID: 28464239.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    17. Endothelial-Mesenchymal Transition in Vascular Calcification of Ins2Akita/+ Mice. PLoS One. 2016; 11(12):e0167936. Guihard PJ, Yao J, Blazquez-Medela AM, Iruela-Arispe L, Boström KI, Yao Y. PMID: 27936229.
      View in: PubMed   Mentions: 9     Fields:    Translation:AnimalsCells
    18. Endothelial-mesenchymal transition in atherosclerotic lesion calcification. Atherosclerosis. 2016 10; 253:124-127. Boström KI, Yao J, Guihard PJ, Blazquez-Medela AM, Yao Y. PMID: 27615595.
      View in: PubMed   Mentions: 21     Fields:    Translation:HumansAnimalsCells
    19. Matrix Gla protein regulates differentiation of endothelial cells derived from mouse embryonic stem cells. Angiogenesis. 2016 Jan; 19(1):1-7. Yao J, Guihard PJ, Blazquez-Medela AM, Guo Y, Liu T, Boström KI, Yao Y. PMID: 26364300.
      View in: PubMed   Mentions: 9     Fields:    Translation:AnimalsCells
    20. Serine Protease Activation Essential for Endothelial-Mesenchymal Transition in Vascular Calcification. Circ Res. 2015 Oct 09; 117(9):758-69. Yao J, Guihard PJ, Blazquez-Medela AM, Guo Y, Moon JH, Jumabay M, Boström KI, Yao Y. PMID: 26265629.
      View in: PubMed   Mentions: 39     Fields:    Translation:HumansAnimalsCells
    21. ABCC6 deficiency is associated with activation of BMP signaling in liver and kidney. FEBS Open Bio. 2015; 5:257-63. Blazquez-Medela AM, Guihard PJ, Yao J, Jumabay M, Lusis AJ, Boström KI, Yao Y. PMID: 25893161.
      View in: PubMed   Mentions: 3     Fields:    
    22. Matrix Gla protein limits pulmonary arteriovenous malformations in ALK1 deficiency. Eur Respir J. 2015 Mar; 45(3):849-52. Boström KI, Guihard P, Blazquez Medela AM, Yao J, Moon JH, Penton A, Yao Y. PMID: 25614167.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimals
    23. Pluripotent stem cells derived from mouse and human white mature adipocytes. Stem Cells Transl Med. 2014 Feb; 3(2):161-71. Jumabay M, Abdmaulen R, Ly A, Cubberly MR, Shahmirian LJ, Heydarkhan-Hagvall S, Dumesic DA, Yao Y, Boström KI. PMID: 24396033.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansAnimalsCells
    24. Reducing Jagged 1 and 2 levels prevents cerebral arteriovenous malformations in matrix Gla protein deficiency. Proc Natl Acad Sci U S A. 2013 Nov 19; 110(47):19071-6. Yao Y, Yao J, Radparvar M, Blazquez-Medela AM, Guihard PJ, Jumabay M, Boström KI. PMID: 24191040.
      View in: PubMed   Mentions: 26     Fields:    Translation:AnimalsCells
    25. A role for the endothelium in vascular calcification. Circ Res. 2013 Aug 16; 113(5):495-504. Yao Y, Jumabay M, Ly A, Radparvar M, Cubberly MR, Boström KI. PMID: 23852538.
      View in: PubMed   Mentions: 84     Fields:    Translation:HumansAnimalsCells
    26. Endothelial differentiation in multipotent cells derived from mouse and human white mature adipocytes. J Mol Cell Cardiol. 2012 Dec; 53(6):790-800. Jumabay M, Abdmaulen R, Urs S, Heydarkhan-Hagvall S, Chazenbalk GD, Jordan MC, Roos KP, Yao Y, Boström KI. PMID: 22999861.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansAnimalsCells
    27. Crossveinless 2 regulates bone morphogenetic protein 9 in human and mouse vascular endothelium. Blood. 2012 May 24; 119(21):5037-47. Yao Y, Jumabay M, Ly A, Radparvar M, Wang AH, Abdmaulen R, Boström KI. PMID: 22474252.
      View in: PubMed   Mentions: 33     Fields:    Translation:HumansAnimalsCells
    28. Patterns of periodic holes created by increased cell motility. Interface Focus. 2012 Aug 06; 2(4):457-64. Chen TH, Guo C, Zhao X, Yao Y, Boström KI, Wong MN, Tintut Y, Demer LL, Ho CM, Garfinkel A. PMID: 22649581.
      View in: PubMed   Mentions:
    29. Concise review: applying stem cell biology to vascular structures. Stem Cells. 2012 Mar; 30(3):386-91. Boström KI, Garfinkel A, Yao Y, Jumabay M. PMID: 22232064.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimalsCells
    30. Abcc6 deficiency causes increased infarct size and apoptosis in a mouse cardiac ischemia-reperfusion model. Arterioscler Thromb Vasc Biol. 2011 Dec; 31(12):2806-12. Mungrue IN, Zhao P, Yao Y, Meng H, Rau C, Havel JV, Gorgels TG, Bergen AA, MacLellan WR, Drake TA, Boström KI, Lusis AJ. PMID: 21979437.
      View in: PubMed   Mentions: 24     Fields:    Translation:AnimalsCells
    31. Matrix Gla protein deficiency causes arteriovenous malformations in mice. J Clin Invest. 2011 Aug; 121(8):2993-3004. Yao Y, Jumabay M, Wang A, Boström KI. PMID: 21765215.
      View in: PubMed   Mentions: 43     Fields:    Translation:HumansAnimalsCells
    32. Activation of vascular bone morphogenetic protein signaling in diabetes mellitus. Circ Res. 2011 Feb 18; 108(4):446-57. Boström KI, Jumabay M, Matveyenko A, Nicholas SB, Yao Y. PMID: 21193740.
      View in: PubMed   Mentions: 84     Fields:    Translation:HumansAnimalsCells
    33. Inhibition of bone morphogenetic proteins protects against atherosclerosis and vascular calcification. Circ Res. 2010 Aug 20; 107(4):485-94. Yao Y, Bennett BJ, Wang X, Rosenfeld ME, Giachelli C, Lusis AJ, Boström KI. PMID: 20576934.
      View in: PubMed   Mentions: 106     Fields:    Translation:Animals
    34. Spontaneously beating cardiomyocytes derived from white mature adipocytes. Cardiovasc Res. 2010 Jan 01; 85(1):17-27. Jumabay M, Zhang R, Yao Y, Goldhaber JI, Boström KI. PMID: 19643806.
      View in: PubMed   Mentions: 30     Fields:    Translation:AnimalsCells
    35. Heat shock protein 70 enhances vascular bone morphogenetic protein-4 signaling by binding matrix Gla protein. Circ Res. 2009 Sep 11; 105(6):575-84. Yao Y, Watson AD, Ji S, Boström KI. PMID: 19661459.
      View in: PubMed   Mentions: 38     Fields:    Translation:HumansAnimalsCells
    36. Expression of vascular endothelial growth factor is coordinately regulated by the activin-like kinase receptors 1 and 5 in endothelial cells. Blood. 2009 Sep 03; 114(10):2197-206. Shao ES, Lin L, Yao Y, Boström KI. PMID: 19506300.
      View in: PubMed   Mentions: 58     Fields:    Translation:HumansAnimalsCells
    37. High-density lipoproteins affect endothelial BMP-signaling by modulating expression of the activin-like kinase receptor 1 and 2. Arterioscler Thromb Vasc Biol. 2008 Dec; 28(12):2266-74. Yao Y, Shao ES, Jumabay M, Shahbazian A, Ji S, Boström KI. PMID: 18948634.
      View in: PubMed   Mentions: 26     Fields:    Translation:HumansAnimalsCells
    38. Proline and gamma-carboxylated glutamate residues in matrix Gla protein are critical for binding of bone morphogenetic protein-4. Circ Res. 2008 May 09; 102(9):1065-74. Yao Y, Shahbazian A, Boström KI. PMID: 18369157.
      View in: PubMed   Mentions: 37     Fields:    Translation:HumansAnimalsCells
    39. Matrix GLA protein, an inhibitory morphogen in pulmonary vascular development. J Biol Chem. 2007 Oct 12; 282(41):30131-42. Yao Y, Nowak S, Yochelis A, Garfinkel A, Boström KI. PMID: 17670744.
      View in: PubMed   Mentions: 30     Fields:    Translation:HumansAnimals
    40. Activin-like kinase receptor 1 (ALK1) in atherosclerotic lesions and vascular mesenchymal cells. Cardiovasc Res. 2007 May 01; 74(2):279-89. Yao Y, Zebboudj AF, Torres A, Shao E, Boström K. PMID: 17074310.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansAnimalsCells
    41. Regulation of bone morphogenetic protein-4 by matrix GLA protein in vascular endothelial cells involves activin-like kinase receptor 1. J Biol Chem. 2006 Nov 10; 281(45):33921-30. Yao Y, Zebboudj AF, Shao E, Perez M, Boström K. PMID: 16950789.
      View in: PubMed   Mentions: 52     Fields:    Translation:HumansAnimalsCells
    42. Matrix GLA protein stimulates VEGF expression through increased transforming growth factor-beta1 activity in endothelial cells. J Biol Chem. 2004 Dec 17; 279(51):52904-13. Boström K, Zebboudj AF, Yao Y, Lin TS, Torres A. PMID: 15456771.
      View in: PubMed   Mentions: 46     Fields:    Translation:HumansAnimalsCells
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